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Jan 2022
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Borna disease virus docks on neuronal DNA double-strand breaks to replicate and dampens neuronal activity

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1. scibot 12 Jan 2022
  
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  DOI: 10.1016/j.isci.2021.103621
  
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sciencedirect.com/science/article/pii/S2589004221015911
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CXCL4 drives fibrosis by promoting several key cellular and molecular processes

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1. scibot 05 Jan 2022
  
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  DOI: 10.1016/j.celrep.2021.110189
  
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sciencedirect.com/science/article/pii/S2211124721016909
Dec 2021
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Association of RanGAP to nuclear pore complex component, RanBP2/Nup358, is required for pupal development in Drosophila

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1. scibot 29 Dec 2021
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11166264/
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CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism

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1. scibot 11 Dec 2021
  
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  DOI: 10.1016/j.isci.2021.103538
  
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STING regulates peripheral nerve regeneration and colony stimulating factor 1 receptor (CSF1R) processing in microglia

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1. scibot 11 Dec 2021
  
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  DOI: 10.1016/j.isci.2021.103434
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8633968/
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The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability

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1. scibot 09 Dec 2021
  
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  DOI: 10.1016/j.celrep.2021.110080
  
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Association of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 With Angiotensin II Type 1 Receptor Impacts Mitochondrial Quality Control, Offering Promise for the Treatment of Vascular Senescence

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1. scibot 04 Dec 2021
  
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  DOI: 10.3389/fcvm.2021.788655
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8637926/
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Glutamine deprivation triggers NAGK-dependent hexosamine salvage

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1. scibot 04 Dec 2021
  
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  DOI: 10.7554/eLife.62644
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8631944/
Nov 2021
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EGFR-mediated epidermal stem cell motility drives skin regeneration through COL17A1 proteolysis

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1. scibot 18 Nov 2021
  
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  DOI: 10.1083/jcb.202012073
  
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rupress.org/jcb/article/220/11/e202012073/212656/EGFR-mediated-epidermal-stem-cell-motility-drives
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TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change

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1. scibot 10 Nov 2021
  
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sciencedirect.com/science/article/pii/S2211124721014583
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A functional genetic toolbox for human tissue-derived organoids

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1. scibot 05 Nov 2021
  
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  DOI: 10.7554/eLife.67886
  
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elifesciences.org/articles/67886
Oct 2021
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p38-mediated cell growth and survival drive rapid embryonic wound repair

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1. scibot 22 Oct 2021
  
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  DOI: 10.1016/j.celrep.2021.109874
  
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sciencedirect.com/science/article/pii/S2211124721013413
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CLIP-170S is a microtubule +TIP variant that confers resistance to taxanes by impairing drug-target engagement

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1. scibot 21 Oct 2021
  
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  DOI: 10.1016/j.devcel.2021.09.023
  
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sciencedirect.com/science/article/pii/S153458072100767X
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Immunohistochemical expression and neurochemical phenotypes of huntingtin-associated protein 1 in the myenteric plexus of mouse gastrointestinal tract

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1. scibot 20 Oct 2021
  
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  DOI: 10.1007/s00441-021-03542-4
  
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link.springer.com/article/10.1007/s00441-021-03542-4
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Plastin and spectrin cooperate to stabilize the actomyosin cortex during cytokinesis

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1. scibot 19 Oct 2021
  
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  DOI: 10.1016/j.cub.2021.09.055
  
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sciencedirect.com/science/article/pii/S0960982221012951
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Opposing motors provide mechanical and functional robustness in the human spindle

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1. scibot 06 Oct 2021
  
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  DOI: 10.1016/j.devcel.2021.09.011
  
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sciencedirect.com/science/article/pii/S1534580721007292
Sep 2021
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Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity

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1. scibot 30 Sep 2021
  
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  DOI: 10.1016/j.cmet.2021.09.003
  
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sciencedirect.com/science/article/pii/S1550413121004228
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Cyclical phosphorylation of LRAP35a and CLASP2 by GSK3β and CK1δ regulates EB1-dependent MT dynamics in cell migration

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1. scibot 16 Sep 2021
  
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  DOI: 10.1016/j.celrep.2021.109687
  
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sciencedirect.com/science/article/pii/S2211124721011347
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TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells

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1. scibot 14 Sep 2021
  
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  DOI: 10.7554/eLife.67259
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8410071/
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Negative charge in the RACK1 loop broadens the translational capacity of the human ribosome

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  DOI: 10.1016/j.celrep.2021.109663
  
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sciencedirect.com/science/article/pii/S2211124721011074
Aug 2021
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Ciliary and extraciliary Gpr161 pools repress hedgehog signaling in a tissue-specific manner

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1. scibot 25 Aug 2021
  
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  DOI: 10.7554/eLife.67121
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8378848/
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Stabilization of Motin family proteins in NF2-deficient cells prevents full activation of YAP/TAZ and rapid tumorigenesis

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1. scibot 25 Aug 2021
  
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  DOI: 10.1016/j.celrep.2021.109596
  
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sciencedirect.com/science/article/pii/S2211124721010342
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LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice

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1. scibot 17 Aug 2021
  
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  DOI: 10.7554/eLife.68227
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8360648/
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Fat body Ire1 regulates lipid homeostasis through the Xbp1s-FoxO axis in Drosophila

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1. scibot 16 Aug 2021
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8333185/
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Rewiring of the ubiquitinated proteome determines ageing in C. elegans

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1. scibot 15 Aug 2021
  
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  DOI: 10.1038/s41586-021-03781-z
  
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nature.com/articles/s41586-021-03781-z
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Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis

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1. scibot 15 Aug 2021
  
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A photo-cross-linking GlcNAc analog enables covalent capture of N-linked glycoprotein-binding partners on the cell surface

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1. scibot 15 Aug 2021
  
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  DOI: 10.1016/j.chembiol.2021.07.007
  
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sciencedirect.com/science/article/pii/S2451945621003470
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Separase cleaves the kinetochore protein Meikin at the meiosis I/II transition

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1. scibot 15 Aug 2021
  
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  DOI: 10.1016/j.devcel.2021.06.019
  
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sciencedirect.com/science/article/pii/S1534580721005268
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miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to impact proteotoxicity and muscle function during aging

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1. scibot 15 Aug 2021
  
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  DOI: 10.7554/eLife.66768
  
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elifesciences.org/articles/66768
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Glycosylphosphatidylinositol biosynthesis and remodeling are required for neural tube closure, heart development, and cranial neural crest cell survival

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1. scibot 14 Aug 2021
  
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  DOI: 10.7554/eLife.45248
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6611694/
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Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females

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1. scibot 13 Aug 2021
  
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sciencedirect.com/science/article/pii/S2211124719306023
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BAG3 is a negative regulator of ciliogenesis in glioblastoma and triple-negative breast cancer cells

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1. scibot 12 Aug 2021
  
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  DOI: 10.1002/jcb.30073
  
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onlinelibrary.wiley.com/doi/10.1002/jcb.30073
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Untitled document

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1. scibot 09 Aug 2021
  
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  DOI: 10.1016/j.celrep.2018.11.002
  
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sciencedirect.com/science/article/pii/S2211124718317315
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Untitled document

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1. scibot 06 Aug 2021
  
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  DOI: 10.1016/j.cub.2018.08.056
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6224608/
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Glucose Sensing by Skeletal Myocytes Couples Nutrient Signaling to Systemic Homeostasis

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1. scibot 06 Aug 2021
  
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  DOI: 10.1016/j.molcel.2017.04.007
  
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sciencedirect.com/science/article/pii/S109727651730237X
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Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation

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1. scibot 03 Aug 2021
  
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  DOI: 10.1016/j.cmet.2018.07.019
  
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cindr, the Drosophila Homolog of the CD2AP Alzheimer’s Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis

1
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  mouse anti-Tubulin Clone DM1A
  
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Cdc42 and its BORG2 and BORG3 effectors control the subcellular localization of septins between actin stress fibers and microtubules

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Quantification of Proteins and Histone Marks in Drosophila Embryos Reveals Stoichiometric Relationships Impacting Chromatin Regulation

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RAB6 and microtubules restrict protein secretion to focal adhesions

1
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  anti–α-tubulin
  
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Translation of CircRNAs

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Protein phosphatase 1 acts as a RIF1 effector to suppress DSB resection prior to Shieldin action

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The RAS GTPase RIT1 compromises mitotic fidelity through spindle assembly checkpoint suppression

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CYRI-A limits invasive migration through macropinosome formation and integrin uptake regulation

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  RRID:AB_477583
  
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Protein-based condensation mechanisms drive the assembly of RNA-rich P granules

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Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition

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Cereblon regulates the proteotoxicity of tau by tuning the chaperone activity of DNAJA1

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Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model

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  DOI: 10.7554/eLife.62718
  
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Budding epithelial morphogenesis driven by cell-matrix versus cell-cell adhesion

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  DOI: 10.1016/j.cell.2021.05.015
  
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Desmosomes polarize and integrate chemical and mechanical signaling to govern epidermal tissue form and function

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DIAPH3 deficiency links microtubules to mitotic errors, defective neurogenesis, and brain dysfunction

1
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PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay

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Overcoming Intrinsic H3K27me3 Imprinting Barriers Improves Post-implantation Development after Somatic Cell Nuclear Transfer

1
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Androgen affects the dynamics of intrinsic plasticity of pyramidal neurons in the CA1 hippocampal subfield in adolescent male rats

1
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Piezo1-Mediated Ca2+ Activities Regulate Brain Vascular Pathfinding during Development

1
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  DOI: 10.1016/j.neuron.2020.07.025
  
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A Membrane-Tethered Ubiquitination Pathway Regulates Hedgehog Signaling and Heart Development

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Distinct Cation Gradients Power Cholesterol Transport at Different Key Points in the Hedgehog Signaling Pathway

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Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling

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Convergence of mammalian RQC and C-end rule proteolytic pathways via alanine tailing

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Donor cell memory confers a metastable state of directly converted cells

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http://biorxiv.org/cgi/content/short/2020.11.11.379099

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Capturing human trophoblast development with naive pluripotent stem cells in vitro

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Pathogenic GRM7 mutations associated with neurodevelopmental disorders impair axon outgrowth and presynaptic terminal development

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Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in Drosophila

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  DOI: 10.7554/eLife.58565
  
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Neddylation is required for presynaptic clustering of mGlu7 and maturation of presynaptic terminals

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  DOI: 10.1038/s12276-021-00585-z
  
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Mar 2021
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High dietary salt amplifies osmoresponsiveness in vasopressin-releasing neurons

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  DOI: 10.1016/j.celrep.2021.108866
  
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Mauve/LYST limits fusion of lysosome-related organelles and promotes centrosomal recruitment of microtubule nucleating proteins

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Plasmodium transcription repressor AP2‐O3 regulates sex‐specific identity of gene expression in female gametocytes

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  DOI: 10.15252/embr.202051660
  
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The Oncogenic Helicase ALC1 Regulates PARP Inhibitor Potency by Trapping PARP2 at DNA Breaks

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The BRCT domains of ECT2 have distinct functions during cytokinesis

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Metabolic conditioning of CD8 + effector T cells for adoptive cell therapy

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Quantification of Proteins and Histone Marks in Drosophila Embryos Reveals Stoichiometric Relationships Impacting Chromatin Regulation

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Destabilization of Long Astral Microtubules via Cdk1-Dependent Removal of GTSE1 from Their Plus Ends Facilitates Prometaphase Spindle Orientation

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5’ValCAC tRNA fragment generated as part of a protective angiogenin response provides prognostic value in amyotrophic lateral sclerosis

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Predicting protein condensate formation using machine learning

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Magnesium efflux from Drosophila Kenyon cells is critical for normal and diet-enhanced long-term memory

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Homogentisic acid induces cytoskeleton and extracellular matrix alteration in alkaptonuric cartilage

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Kinesin-4 KIF21B limits microtubule growth to allow rapid centrosome polarization in T cells

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Cilium Axoneme Internalization and Degradation in Chytrid Fungi

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Piwil1 Regulates Glioma Stem Cell Maintenance and Glioblastoma Progression

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chTOG is a conserved mitotic error correction factor

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Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q

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Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD

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The Aurora-A/TPX2 Axis Directs Spindle Orientation in Adherent Human Cells by Regulating NuMA and Microtubule Stability

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Doubling the resolution of a confocal spinning-disk microscope using image scanning microscopy

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Hedgehog Pathway Activation Requires Coreceptor-Catalyzed, Lipid-Dependent Relay of the Sonic Hedgehog Ligand

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An Acquired and Endogenous Glycocalyx Forms a Bidirectional “Don’t Eat” and “Don’t Eat Me” Barrier to Phagocytosis

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The Perinuclear ER Scales Nuclear Size Independently of Cell Size in Early Embryos

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Expression of huntingtin-associated protein 1 in adult mouse dorsal root ganglia and its neurochemical characterization in reference to sensory neuron subpopulations

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Ordered dephosphorylation initiated by the selective proteolysis of cyclin B drives mitotic exit

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Mechanistic Target of Rapamycin Regulates the Oligodendrocyte Cytoskeleton during Myelination

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A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV

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SpiCee: A Genetic Tool for Subcellular and Cell-Specific Calcium Manipulation

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The Lamin B receptor is essential for cholesterol synthesis and perturbed by disease-causing mutations

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N‐linked glycosylation of the mGlu7 receptor regulates the forward trafficking and transsynaptic interaction with Elfn1

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Naive Pluripotent Stem Cells Exhibit Phenotypic Variability that Is Driven by Genetic Variation

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The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency

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Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis

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Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells

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Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

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The Mitochondrial Protein MAVS Stabilizes p53 to Suppress Tumorigenesis

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Egfr Signaling Is a Major Regulator of Ecdysone Biosynthesis in the Drosophila Prothoracic Gland

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Antagonistic control of Caenorhabditis elegans germline stem cell proliferation and differentiation by PUF proteins FBF-1 and FBF-2

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MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation

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Microneedle manipulation of the mammalian spindle reveals specialized, short-lived reinforcement near chromosomes

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RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

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The membrane periodic skeleton is an actomyosin network that regulates axonal diameter and conduction

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Quantitative immunoblotting analyses reveal that the abundance of actin, tubulin, synaptophysin and EEA1 proteins is altered in the brains of aged mice

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Male meiotic spindle features that efficiently segregate paired and lagging chromosomes

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HLH-30/TFEB Is a Master Regulator of Reproductive Quiescence

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Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas

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Pathogenic DDX3X Mutations Impair RNA Metabolism and Neurogenesis during Fetal Cortical Development

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Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age- and combination-specific phenotypic profiles in Drosophila

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CCDC57 Cooperates with Microtubules and Microcephaly Protein CEP63 and Regulates Centriole Duplication and Mitotic Progression

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MYC Dysregulates Mitosis, Revealing Cancer Vulnerabilities

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Ribosome Recycling by ABCE1 Links Lysosomal Function and Iron Homeostasis to 3ʹ UTR-Directed Regulation and Nonsense-Mediated Decay

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Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain

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A FLCN-TFE3 Feedback Loop Prevents Excessive Glycogenesis and Phagocyte Activation by Regulating Lysosome Activity

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High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening

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Cryo-EM structure of VASH1-SVBP bound to microtubules

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Suppression of Ribosomal Pausing by eIF5A Is Necessary to Maintain the Fidelity of Start Codon Selection

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Molecular Strategies of Meiotic Cheating by Selfish Centromeres

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Ghrelin-Induced Sodium Reabsorption is Mediated by PKA and Microtubule-Dependent αE Na C Translocation In Female Rats

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Dynamic Polarization of the Multiciliated Planarian Epidermis between Body Plan Landmarks

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FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy

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Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration

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MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition

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Identification of a Paracrine Signaling Mechanism Linking CD34high Progenitors to the Regulation of Visceral Fat Expansion and Remodeling

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Alternative Translation Initiation Generates a Functionally Distinct Isoform of the Stress-Activated Protein Kinase MK2

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CCDC84 Acetylation Oscillation Regulates Centrosome Duplication by Modulating HsSAS-6 Degradation

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Differences in Mitotic Spindle Architecture in Mammalian Neural Stem Cells Influence Mitotic Accuracy during Brain Development

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Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform

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P Granules Protect RNA Interference Genes from Silencing by piRNAs

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A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate

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Nedd4 E3 ligase and beta-arrestins regulate ubiquitination, trafficking, and stability of the mGlu7 receptor

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The transcription factor odd-paired regulates temporal identity in transit-amplifying neural progenitors via an incoherent feed-forward loop

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SponGee: A Genetic Tool for Subcellular and Cell-Specific cGMP Manipulation

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Planar Cell Polarity Effector Proteins Inturned and Fuzzy Form a Rab23 GEF Complex

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Naa10p Inhibits Beige Adipocyte-Mediated Thermogenesis through N-α-acetylation of Pgc1α

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Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis

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Sustained GRK2-dependent CREB activation is essential for α2-adrenergic receptor-induced PC12 neuronal differentiation

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The HSPG Glypican Regulates Experience-Dependent Synaptic and Behavioral Plasticity by Modulating the Non-Canonical BMP Pathway

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A Septin Double Ring Controls the Spatiotemporal Organization of the ESCRT Machinery in Cytokinetic Abscission

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Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation

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N-WASP Control of LPAR1 Trafficking Establishes Response to Self-Generated LPA Gradients to Promote Pancreatic Cancer Cell Metastasis

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OLFR734 Mediates Glucose Metabolism as a Receptor of Asprosin

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Miro1 Marks Parkinson’s Disease Subset and Miro1 Reducer Rescues Neuron Loss in Parkinson’s Models

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Mediation of the Acute Stress Response by the Skeleton

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Memo1-Mediated Tiling of Radial Glial Cells Facilitates Cerebral Cortical Development

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Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B

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The p97–Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8

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Non-enzymatic Activity of the α-Tubulin Acetyltransferase αTAT Limits Synaptic Bouton Growth in Neurons

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Compromised Mitochondrial Protein Import Acts as a Signal for UPRmt

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Pathology of white matter integrity in three major white matter fasciculi: A post‐mortem study of schizophrenia and treatment status

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Plk4 Regulates Centriole Asymmetry and Spindle Orientation in Neural Stem Cells

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Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS

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Oxidative Stress Orchestrates Cell Polarity to Promote Embryonic Wound Healing

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Retrograde transport of γ‐secretase from endosomes to the trans‐Golgi network regulates Aβ42 production

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Rotenone inhibits axonogenesis via an Lfc/RhoA/ROCK pathway in cultured hippocampal neurons

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Dynamic UTR Usage Regulates Alternative Translation to Modulate Gap Junction Formation during Stress and Aging

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Microtubule End-Clustering Maintains a Steady-State Spindle Shape

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Distribution of HAP1-immunoreactive Cells in the Retrosplenial–retrohippocampal Area of Adult Rat Brain and Its Application to a Refined Neuroanatomical Understanding of the Region

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Alpha-Amino-Beta-Carboxy-Muconate-Semialdehyde Decarboxylase Controls Dietary Niacin Requirements for NAD+ Synthesis

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A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression

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Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction

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Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration

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The THO Complex Coordinates Transcripts for Synapse Development and Dopamine Neuron Survival

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Presynaptic Inhibition Selectively Gates Auditory Transmission to the Brainstem Startle Circuit

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Astrocyte-derived Jagged-1 mitigates deleterious Notch signaling in amyotrophic lateral sclerosis

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Polarity of Neuronal Membrane Traffic Requires Sorting of Kinesin Motor Cargo during Entry into Dendrites by a Microtubule-Associated Septin

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Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1.

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Nek9 Phosphorylation Defines a New Role for TPX2 in Eg5-Dependent Centrosome Separation before Nuclear Envelope Breakdown

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Esrrb Unlocks Silenced Enhancers for Reprogramming to Naive Pluripotency

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The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation

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Human LINE-1 retrotransposition requires a metastable coiled coil and a positively charged N-terminus in L1ORF1p

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Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy

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PINK1 Phosphorylates MIC60/Mitofilin to Control Structural Plasticity of Mitochondrial Crista Junctions

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Impairing L-Threonine Catabolism Promotes Healthspan through Methylglyoxal-Mediated Proteohormesis

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The HCMV Assembly Compartment Is a Dynamic Golgi-Derived MTOC that Controls Nuclear Rotation and Virus Spread

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https://www.ncbi.nlm.nih.gov/pubmed/29290584

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Hyperinnervation improves Xenopus laevis limb regeneration

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Male Brown Fat–Specific Double Knockout of IGFIR/IR: Atrophy, Mitochondrial Fission Failure, Impaired Thermogenesis, and Obesity

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