383 Matching Annotations
  1. Jul 2021
  2. www.sciencedirect.com www.sciencedirect.com
    Protein phosphatase 1 acts as a RIF1 effector to suppress DSB resection prior to Shieldin action
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      DOI: 10.1016/j.celrep.2021.109383

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    sciencedirect.com/science/article/pii/S2211124721007816
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    The RAS GTPase RIT1 compromises mitotic fidelity through spindle assembly checkpoint suppression
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    sciencedirect.com/science/article/pii/S0960982221008253
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CYRI-A limits invasive migration through macropinosome formation and integrin uptake regulation
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      DOI: 10.1083/jcb.202012114

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    ncbi.nlm.nih.gov/pmc/articles/PMC8236918/
  5. elifesciences.org elifesciences.org
    Protein-based condensation mechanisms drive the assembly of RNA-rich P granules
    1
    1. scibot 03 Jul 2021
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      DOI: 10.7554/eLife.63698

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    elifesciences.org/articles/63698
  6. Jun 2021
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    Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
    1
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    sciencedirect.com/science/article/pii/S2211124721006628
  8. www.jneurosci.org www.jneurosci.org
    Cereblon regulates the proteotoxicity of tau by tuning the chaperone activity of DNAJA1
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      DOI: 10.1523/JNEUROSCI.2494-20.2021

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    jneurosci.org/content/41/24/5138
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model
    1
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      DOI: 10.7554/eLife.62718

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    ncbi.nlm.nih.gov/pmc/articles/PMC8221807/
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    Budding epithelial morphogenesis driven by cell-matrix versus cell-cell adhesion
    1
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      DOI: 10.1016/j.cell.2021.05.015

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    sciencedirect.com/science/article/pii/S0092867421006322
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    Desmosomes polarize and integrate chemical and mechanical signaling to govern epidermal tissue form and function
    1
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    sciencedirect.com/science/article/pii/S0960982221006801
  12. May 2021
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DIAPH3 deficiency links microtubules to mitotic errors, defective neurogenesis, and brain dysfunction
    1
    1. scibot 13 May 2021
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      DOI: 10.7554/eLife.61974

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    ncbi.nlm.nih.gov/pmc/articles/PMC8102060/
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    PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay
    1
    1. scibot 13 May 2021
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      DOI: 10.1016/j.devcel.2021.04.019

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    sciencedirect.com/science/article/pii/S1534580721003579
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    Overcoming Intrinsic H3K27me3 Imprinting Barriers Improves Post-implantation Development after Somatic Cell Nuclear Transfer
    1
    1. scibot 09 May 2021
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      DOI: 10.1016/j.stem.2020.05.014

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    sciencedirect.com/science/article/pii/S1934590920302125
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    Androgen affects the dynamics of intrinsic plasticity of pyramidal neurons in the CA1 hippocampal subfield in adolescent male rats
    1
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    sciencedirect.com/science/article/pii/S0306452220303195
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    Piezo1-Mediated Ca2+ Activities Regulate Brain Vascular Pathfinding during Development
    1
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      DOI: 10.1016/j.neuron.2020.07.025

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    sciencedirect.com/science/article/pii/S0896627320305699
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    A Membrane-Tethered Ubiquitination Pathway Regulates Hedgehog Signaling and Heart Development
    1
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      DOI: 10.1016/j.devcel.2020.08.012

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    sciencedirect.com/science/article/pii/S1534580720306705
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    Distinct Cation Gradients Power Cholesterol Transport at Different Key Points in the Hedgehog Signaling Pathway
    1
    1. scibot 05 May 2021
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      DOI: 10.1016/j.devcel.2020.08.002

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    sciencedirect.com/science/article/pii/S1534580720306006
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    Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling
    1
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      DOI: 10.1016/j.devcel.2020.06.034

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    sciencedirect.com/science/article/pii/S1534580720305426
  21. Apr 2021
  22. www.sciencedirect.com www.sciencedirect.com
    Convergence of mammalian RQC and C-end rule proteolytic pathways via alanine tailing
    1
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      DOI: 10.1016/j.molcel.2021.03.004

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    sciencedirect.com/science/article/pii/S1097276521001726
  23. www.sciencedirect.com www.sciencedirect.com
    Donor cell memory confers a metastable state of directly converted cells
    1
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      DOI: 10.1016/j.stem.2021.02.023

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    sciencedirect.com/science/article/pii/S1934590921000746
  24. europepmc.org europepmc.org
    http://biorxiv.org/cgi/content/short/2020.11.11.379099
    1
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      DOI: 10.1101/2020.11.11.379099

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    europepmc.org/articles/PMC7668735/
  25. www.sciencedirect.com www.sciencedirect.com
    Capturing human trophoblast development with naive pluripotent stem cells in vitro
    1
    1. scibot 09 Apr 2021
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      DOI: 10.1016/j.stem.2021.03.013

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    sciencedirect.com/science/article/pii/S1934590921001193
  26. www.jneurosci.org www.jneurosci.org
    Pathogenic GRM7 mutations associated with neurodevelopmental disorders impair axon outgrowth and presynaptic terminal development
    1
    1. scibot 08 Apr 2021
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      DOI: 10.1523/JNEUROSCI.2108-20.2021

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    jneurosci.org/content/41/11/2344
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in Drosophila
    1
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      DOI: 10.7554/eLife.58565

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    ncbi.nlm.nih.gov/pmc/articles/PMC8007214/
  28. www.nature.com www.nature.com
    Neddylation is required for presynaptic clustering of mGlu7 and maturation of presynaptic terminals
    1
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      DOI: 10.1038/s12276-021-00585-z

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    nature.com/articles/s12276-021-00585-z
  29. Mar 2021
  30. www.sciencedirect.com www.sciencedirect.com
    High dietary salt amplifies osmoresponsiveness in vasopressin-releasing neurons
    1
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      DOI: 10.1016/j.celrep.2021.108866

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    sciencedirect.com/science/article/pii/S2211124721001807
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    Mauve/LYST limits fusion of lysosome-related organelles and promotes centrosomal recruitment of microtubule nucleating proteins
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      DOI: 10.1016/j.devcel.2021.02.019

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    sciencedirect.com/science/article/pii/S1534580721001593
  32. www.embopress.org www.embopress.org
    Plasmodium transcription repressor AP2‐O3 regulates sex‐specific identity of gene expression in female gametocytes
    1
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      DOI: 10.15252/embr.202051660

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    embopress.org/doi/abs/10.15252/embr.202051660
  33. www.sciencedirect.com www.sciencedirect.com
    The Oncogenic Helicase ALC1 Regulates PARP Inhibitor Potency by Trapping PARP2 at DNA Breaks
    1
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    sciencedirect.com/science/article/pii/S1097276520306924
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    The BRCT domains of ECT2 have distinct functions during cytokinesis
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    sciencedirect.com/science/article/pii/S2211124721001194
  35. Feb 2021
  36. www.nature.com www.nature.com
    Metabolic conditioning of CD8 + effector T cells for adoptive cell therapy
    1
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      DOI: 10.1038/s42255-020-0256-z

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    nature.com/articles/s42255-020-0256-z
  37. www.sciencedirect.com www.sciencedirect.com
    Quantification of Proteins and Histone Marks in Drosophila Embryos Reveals Stoichiometric Relationships Impacting Chromatin Regulation
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    sciencedirect.com/science/article/pii/S1534580719307671
  38. www.cell.com www.cell.com
    Destabilization of Long Astral Microtubules via Cdk1-Dependent Removal of GTSE1 from Their Plus Ends Facilitates Prometaphase Spindle Orientation
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    cell.com/current-biology/abstract/S0960-9822(20)31752-8
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    5’ValCAC tRNA fragment generated as part of a protective angiogenin response provides prognostic value in amyotrophic lateral sclerosis
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      DOI: 10.1093/braincomms/fcaa138

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    Predicting protein condensate formation using machine learning
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  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Magnesium efflux from Drosophila Kenyon cells is critical for normal and diet-enhanced long-term memory
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      DOI: 10.7554/eLife.61339

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    ncbi.nlm.nih.gov/pmc/articles/PMC7843133/
  42. Jan 2021
  43. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Homogentisic acid induces cytoskeleton and extracellular matrix alteration in alkaptonuric cartilage
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      DOI: 10.1002/jcp.30284

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    onlinelibrary.wiley.com/doi/10.1002/jcp.30284
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinesin-4 KIF21B limits microtubule growth to allow rapid centrosome polarization in T cells
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      DOI: 10.7554/eLife.62876

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    ncbi.nlm.nih.gov/pmc/articles/PMC7817182/
  45. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cilium Axoneme Internalization and Degradation in Chytrid Fungi
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      DOI: 10.1002/cm.21637

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    onlinelibrary.wiley.com/doi/10.1002/cm.21637
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    Piwil1 Regulates Glioma Stem Cell Maintenance and Glioblastoma Progression
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    sciencedirect.com/science/article/pii/S2211124720315114
  47. elifesciences.org elifesciences.org
    chTOG is a conserved mitotic error correction factor
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      DOI: 10.7554/eLife.61773

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  48. Dec 2020
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    The Aurora-A/TPX2 Axis Directs Spindle Orientation in Adherent Human Cells by Regulating NuMA and Microtubule Stability
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    Hedgehog Pathway Activation Requires Coreceptor-Catalyzed, Lipid-Dependent Relay of the Sonic Hedgehog Ligand
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    Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS
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    Rotenone inhibits axonogenesis via an Lfc/RhoA/ROCK pathway in cultured hippocampal neurons
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    Dynamic UTR Usage Regulates Alternative Translation to Modulate Gap Junction Formation during Stress and Aging
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    Distribution of HAP1-immunoreactive Cells in the Retrosplenial–retrohippocampal Area of Adult Rat Brain and Its Application to a Refined Neuroanatomical Understanding of the Region
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    A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression
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    The THO Complex Coordinates Transcripts for Synapse Development and Dopamine Neuron Survival
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    Polarity of Neuronal Membrane Traffic Requires Sorting of Kinesin Motor Cargo during Entry into Dendrites by a Microtubule-Associated Septin
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    Nek9 Phosphorylation Defines a New Role for TPX2 in Eg5-Dependent Centrosome Separation before Nuclear Envelope Breakdown
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    Male Brown Fat–Specific Double Knockout of IGFIR/IR: Atrophy, Mitochondrial Fission Failure, Impaired Thermogenesis, and Obesity
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    NuMA recruits dynein activity to microtubule minus-ends at mitosis
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    Heavy Alcohol Consumption Effects on Blood Pressure and on Kidney Structure Persist After Long-Term Withdrawal
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      RRID:AB_477583

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      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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    academic.oup.com/jes/article/1/7/965/3861375
  175. www.sciencedirect.com www.sciencedirect.com
    Dynamic Control of X Chromosome Conformation and Repression by a Histone H4K20 Demethylase
    1
    1. scibot 08 Nov 2017
      RRID:AB_477583

      Curator: @Jmenke

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      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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      RRID:AB_477583 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867417308772
  176. academic.oup.com academic.oup.com
    Untitled document
    1
    1. scibot 08 Nov 2017
      RRID:AB_477583

      Curator: @patriciaelyse_

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      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

      SciCrunch record: RRID:AB_477583

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      RRID:AB_477583 RRIDCUR:Validated
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    academic.oup.com/jes/article/1/7/965/3861375/17-Estradiol-Promotes-Islet-Cell-Proliferation-in
  177. www.sciencedirect.com www.sciencedirect.com
    An RNAi Screen in a Novel Model of Oriented Divisions Identifies the Actin-Capping Protein Z β as an Essential Regulator of Spindle Orientation
    1
    1. scibot 08 Nov 2017
      RRID:AB_477583

      Curator: @Jmenke

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      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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      RRID:AB_477583 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0960982217307923
  178. www.sciencedirect.com www.sciencedirect.com
    Golgi-Resident Gαo Promotes Protrusive Membrane Dynamics
    1
    1. scibot 08 Nov 2017
      RRID:AB_477583

      Curator: @patriciaelyse_

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      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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      RRID:AB_477583 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S009286741730822X
  179. www.sciencedirect.com www.sciencedirect.com
    The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines
    1
    1. scibot 08 Nov 2017
      RRID:AB_477583

      Curator: @Jmenke

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      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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    sciencedirect.com/science/article/pii/S2451945617302337
  180. www.sciencedirect.com www.sciencedirect.com
    Drosophila Histone Demethylase KDM4A Has Enzymatic and Non-enzymatic Roles in Controlling Heterochromatin Integrity
    1
    1. scibot 08 Nov 2017
      RRID:AB_477583

      Curator: @chewbeccax

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      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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      RRID:AB_477583 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1534580717305026
  181. www.sciencedirect.com www.sciencedirect.com
    GCL and CUL3 Control the Switch between Cell Lineages by Mediating Localized Degradation of an RTK
    1
    1. scibot 08 Nov 2017
      RRID:AB_477583

      Curator: @chewbeccax

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      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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      RRID:AB_477583 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1534580717305105
  182. www.sciencedirect.com www.sciencedirect.com
    Regulatory Expansion in Mammals of Multivalent hnRNP Assemblies that Globally Control Alternative Splicing
    1
    1. scibot 08 Nov 2017
      AB_477583

      Curator: @chewbeccax

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      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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      RRID:AB_477583 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867417307560
  183. www.sciencedirect.com www.sciencedirect.com
    Mapping Load-Bearing in the Mammalian Spindle Reveals Local Kinetochore Fiber Anchorage that Provides Mechanical Isolation and Redundancy
    1
    1. scibot 08 Nov 2017
      AB_477583

      Curator: @chewbeccax

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      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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      RRID:AB_477583 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0960982217307200
  184. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The HDAC6 Inhibitor Tubacin Induces Release of CD133+ Extracellular Vesicles from Cancer Cells
    1
    1. scibot 08 Nov 2017
      AB_477583

      Curator: @chewbeccax

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      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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    onlinelibrary.wiley.com/doi/10.1002/jcb.26095/full
  185. www.sciencedirect.com www.sciencedirect.com
    Structure of the ACF7 EF-Hand-GAR Module and Delineation of Microtubule Binding Determinants
    1
    1. scibot 08 Nov 2017
      AB_477583

      Curator: @chewbeccax

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      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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      RRID:AB_477583 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0969212617301405
  186. www.sciencedirect.com www.sciencedirect.com
    Lck/Hck/Fgr-Mediated Tyrosine Phosphorylation Negatively Regulates TBK1 to Restrain Innate Antiviral Responses
    1
    1. scibot 08 Nov 2017
      AB_477583

      Curator: @chewbeccax

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      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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      RRID:AB_477583 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1931312817302032
  187. www.sciencedirect.com www.sciencedirect.com
    Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated
    1
    1. scibot 08 Nov 2017
      AB_477583

      Curator: @chewbeccax

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      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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      RRID:AB_477583 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867417305858
  188. www.sciencedirect.com www.sciencedirect.com
    Hec1 Tail Phosphorylation Differentially Regulates Mammalian Kinetochore Coupling to Polymerizing and Depolymerizing Microtubules
    1
    1. scibot 08 Nov 2017
      AB_477583

      Curator: @Zeljana_Babic

      Resource used:

      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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      RRID:AB_477583 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0960982217305031
  189. www.sciencedirect.com www.sciencedirect.com
    Large Cytoplasm Is Linked to the Error-Prone Nature of Oocytes
    1
    1. scibot 08 Nov 2017
      AB_477583

      Curator: @gabimpine

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      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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      RRID:AB_477583 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1534580717303027
  190. www.cell.com www.cell.com
    Mutation of the Human Circadian Clock Gene CRY1 in Familial Delayed Sleep Phase Disorder
    1
    1. scibot 08 Nov 2017
      AB_477583

      Curator: @Zeljana_Babic

      Resource used:

      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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      RRID:AB_477583 RRIDCUR:Validated
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    cell.com/action/showMethods
  191. www.sciencedirect.com www.sciencedirect.com
    Mutation of the Human Circadian Clock Gene CRY1 in Familial Delayed Sleep Phase Disorder
    1
    1. scibot 08 Nov 2017
      AB_477583

      Curator: @gabimpine

      Resource used:

      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

      SciCrunch record: RRID:AB_477583

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      RRID:AB_477583 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S009286741730346X
  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The BLOC-1 Subunit Pallidin Facilitates Activity-Dependent Synaptic Vesicle Recycling
    1
    1. scibot 08 Nov 2017
      mouse anti-α-tubulin 1:2000 (T6199, Sigma-Aldrich)

      Curator: @chewbeccax

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      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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      RRID:AB_477583 RRIDCUR:Missing
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    ncbi.nlm.nih.gov/pmc/articles/PMC5356223/
  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Filamin, a synaptic organizer in Drosophila, determines glutamate receptor composition and membrane growth
    1
    1. scibot 08 Nov 2017
      AB_477583

      Resource used:

      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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    ncbi.nlm.nih.gov/pmc/articles/PMC5173320/
  194. www.sciencedirect.com www.sciencedirect.com
    Immunohistochemical analysis of huntingtin-associated protein 1 in adult rat spinal cord and its regional relationship with androgen receptor
    1
    1. scibot 08 Nov 2017
      AB_477583

      Curator: @gabimpine

      Resource used:

      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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      RRID:AB_477583 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0306452216305930
  195. www.sciencedirect.com www.sciencedirect.com
    A Portrait of the Human Organelle Proteome In Space and Time during Cytomegalovirus Infection
    1
    1. scibot 08 Nov 2017
      AB_477583

      Resource used:

      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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    sciencedirect.com/science/article/pii/S2405471216302897
  196. www.sciencedirect.com www.sciencedirect.com
    The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes
    1
    1. scibot 08 Nov 2017
      RIID: AB_477583

      Curator: @jcabotaj

      Curator note: "RRID" spelled wrong

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      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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      RRID:AB_477583
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    sciencedirect.com/science/article/pii/S0969996114001727
  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Granulin Knock Out Zebrafish Lack Frontotemporal Lobar Degeneration and Neuronal Ceroid Lipofuscinosis Pathology
    1
    1. scibot 08 Nov 2017
      AB_477583

      Curator: @gabimpine

      Resource used:

      (Sigma-Aldrich Cat# T6199, RRID:AB_477583)

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      RRID:AB_477583 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC4365039/