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  1. Jan 2020
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    Calorie-Restriction-Induced Insulin Sensitivity Is Mediated by Adipose mTORC2 and Not Required for Lifespan Extension
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    p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas
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    Mass Cytometry Reveals Global Immune Remodeling with Multi-lineage Hypersensitivity to Type I Interferon in Down Syndrome
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    NOX1-Dependent mTORC1 Activation via S100A9 Oxidation in Cancer Stem-like Cells Leads to Colon Cancer Progression
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    Mechanical loading stimulates hypertrophy in tissue‐engineered skeletal muscle: Molecular and phenotypic responses
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    Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb
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    Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy
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    mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux
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    Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs
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    Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells
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    The GATOR complex regulates an essential response to meiotic double-stranded breaks in Drosophila
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    Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer
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    Tumor Heterogeneity Underlies Differential Cisplatin Sensitivity in Mouse Models of Small-Cell Lung Cancer
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    Lysosome Positioning Influences mTORC2 and AKT Signaling
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    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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    Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer
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    New Noonan syndrome model mice with RIT1 mutation exhibit cardiac hypertrophy and susceptibility to β-adrenergic stimulation-induced cardiac fibrosis
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    MicroRNA-29 enhances autophagy and cleanses exogenous mutant αB-crystallin in retinal pigment epithelial cells
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      DOI: 10.1002/hipo.23068

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  34. Nov 2018
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    Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC
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    TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy
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    The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment
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    Protein Kinase C Epsilon Deletion in Adipose Tissue, but Not in Liver, Improves Glucose Tolerance
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    mTOR Regulates Phase Separation of PGL Granules to Modulate Their Autophagic Degradation
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    Autocrine Mfge8 Signaling Prevents Developmental Exhaustion of the Adult Neural Stem Cell Pool
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    Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
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    mTORC1 Activation during Repeated Regeneration Impairs Somatic Stem Cell Maintenance
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    Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy
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    Adipocyte p62/SQSTM1 Suppresses Tumorigenesis through Opposite Regulations of Metabolism in Adipose Tissue and Tumor
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    mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma
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    Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations
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    mTORC1 Inactivation Promotes Colitis-Induced Colorectal Cancer but Protects from APC Loss-Dependent Tumorigenesis
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  49. Nov 2017
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    The Kinase mTORC1 Promotes the Generation and Suppressive Function of Follicular Regulatory T Cells
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    mTOR Inhibition Restores Amino Acid Balance in Cells Dependent on Catabolism of Extracellular Protein
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  52. www.jneurosci.org www.jneurosci.org
    PTEN Loss Increases the Connectivity of Fast Synaptic Motifs and Functional Connectivity in a Developing Hippocampal Network
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  53. elifesciences.org elifesciences.org
    Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system
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    Prosapip1-Dependent Synaptic Adaptations in the Nucleus Accumbens Drive Alcohol Intake, Seeking, and Reward
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    A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice
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    Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism
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    TREM2 Maintains Microglial Metabolic Fitness in Alzheimer’s Disease
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    Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase
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    LARP1 functions as a molecular switch for mTORC1-mediated translation of an essential class of mRNAs
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    mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT
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    Time-Resolved Proteomics Extends Ribosome Profiling-Based Measurements of Protein Synthesis Dynamics
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    An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice
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  63. elifesciences.org elifesciences.org
    SF-1 expression in the hypothalamus is required for beneficial metabolic effects of exercise
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  64. elifesciences.org elifesciences.org
    Dynamics of mTORC1 activation in response to amino acids
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    L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity
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  66. elifesciences.org elifesciences.org
    Insulin signaling controls neurotransmission via the 4eBP-dependent modification of the exocytotic machinery
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic analysis of BRAFV600E melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis
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