402 Matching Annotations
  1. Apr 2022
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitigating Effect of Estrogen in Alzheimer’s Disease-Mimicking Cerebral Organoid
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    ncbi.nlm.nih.gov/pmc/articles/PMC8990972/
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    Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma
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    sciencedirect.com/science/article/pii/S2211124722003898
  4. Mar 2022
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The L467F-F508del Complex Allele Hampers Pharmacological Rescue of Mutant CFTR by Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis Patients: The Value of the Ex Vivo Nasal Epithelial Model to Address Non-Responders to CFTR-Modulating Drugs
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    ncbi.nlm.nih.gov/pmc/articles/PMC8952007/
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    Pathogen size alters C-type lectin receptor signaling in dendritic cells to influence CD4 Th9 cell differentiation
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    sciencedirect.com/science/article/pii/S2211124722003114
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    Postnatal regulation of B-1a cell development and survival by the CIC-PER2-BHLHE41 axis
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    sciencedirect.com/science/article/pii/S2211124722001073
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    Abi1 mediates airway smooth muscle cell proliferation and airway remodeling via Jak2/STAT3 signaling
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    sciencedirect.com/science/article/pii/S2589004222001031
  9. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Aggravation of pulmonary fibrosis after knocking down the aryl hydrocarbon receptor in the insulin-like growth factor 1 receptor pathway
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15806
  10. Feb 2022
  11. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Coronin 1A facilitates calcium mobilization and promotes astrocyte reactivity in HIV-1 neuropathogenesis
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fba.2021-00109
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemogenetic manipulation of microglia inhibits neuroinflammation and neuropathic pain in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC7897256/
  13. academic.oup.com academic.oup.com
    Growth hormone-induced STAT5B regulates Star gene expression through a cooperation with cJUN in mouse MA-10 Leydig cells
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    academic.oup.com/endo/article/163/2/bqab267/6490116
  14. Jan 2022
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone Acetylation Defects in Brain Precursor Cells: A Potential Pathogenic Mechanism Causing Proliferation and Differentiation Dysfunctions in Mitochondrial Aspartate-Glutamate Carrier Isoform 1 Deficiency
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    ncbi.nlm.nih.gov/pmc/articles/PMC8790092/
  16. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A new therapeutic effect of fenofibrate in Duchenne muscular dystrophy: The promotion of myostatin degradation
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15678
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    Cas11 enables genome engineering in human cells with compact CRISPR-Cas3 systems
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    sciencedirect.com/science/article/pii/S1097276521011370
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of a dihydropyridine scaffold that blocks ryanodine receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC8760560/
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    Lipid droplet dynamics regulate adult muscle stem cell fate
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    sciencedirect.com/science/article/pii/S2211124721017794
  20. Dec 2021
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Artemisinin Mediates Its Tumor-Suppressive Activity in Hepatocellular Carcinoma Through Targeted Inhibition of FoxM1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8652299/
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    GFAT2 mediates cardiac hypertrophy through HBP-O-GlcNAcylation-Akt pathway
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    sciencedirect.com/science/article/pii/S2589004221014887
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    Methods to separate nuclear soluble fractions reflecting localizations in living cells
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    sciencedirect.com/science/article/pii/S2589004221014747
  24. Nov 2021
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states
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    ncbi.nlm.nih.gov/pmc/articles/PMC8555985/
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    SdhA blocks disruption of the Legionella-containing vacuole by hijacking the OCRL phosphatase
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    sciencedirect.com/science/article/pii/S2211124721013644
  27. Oct 2021
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    Homeostatic plasticity induced by increased acetylcholine release at the mouse neuromuscular junction.
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    sciencedirect.com/science/article/pii/S0197458021003225
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    Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2
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    sciencedirect.com/science/article/pii/S2589004221011640
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    ABL allosteric inhibitors synergize with statins to enhance apoptosis of metastatic lung cancer cells
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    sciencedirect.com/science/article/pii/S2211124721013504
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    Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress
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    Cancer cell immune mimicry delineates onco-immunologic modulation
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  33. Sep 2021
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FKBP51 Affects TNF-Related Apoptosis Inducing Ligand Response in Melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC8473884/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Complement Factor B Mediates Ocular Angiogenesis through Regulating the VEGF Signaling Pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC8431595/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens
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    ncbi.nlm.nih.gov/pmc/articles/PMC8423448/
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    Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species
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    sciencedirect.com/science/article/pii/S0092867421010023
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    Activating a collaborative innate-adaptive immune response to control metastasis
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    sciencedirect.com/science/article/pii/S1535610821004451
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    FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington’s disease
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    sciencedirect.com/science/article/pii/S2211124721010925
  40. Aug 2021
  41. www.sciencedirect.com www.sciencedirect.com
    Metabolic plasticity drives development during mammalian embryogenesis
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  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma
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    ncbi.nlm.nih.gov/pmc/articles/PMC7887036/
  43. academic.oup.com academic.oup.com
    Identification of novel genes and pathways regulated by the orphan nuclear receptor COUP-TFII in mouse MA-10 Leydig cells†
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    academic.oup.com/biolreprod/advance-article/doi/10.1093/biolre/ioab131/6315292
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    Decreased Activity of the Ghrhr and Gh Promoters Causes Dominantly Inherited GH Deficiency in Humanized GH1 Mouse Models
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    academic.oup.com/endo/article/160/11/2673/5552702
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  47. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fisetin provides antidepressant effects by activating the TrkB signal pathway in mice
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14226/full
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    onlinelibrary.wiley.com/doi/abs/10.1002/cne.23691
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    Acetylation of Cytidine in mRNA Promotes Translation Efficiency
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    sciencedirect.com/science/article/pii/S0092867418313837
  50. Jul 2021
  51. elifesciences.org elifesciences.org
    KSHV-encoded vCyclin can modulate HIF1α levels to promote DNA replication in hypoxia
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    elifesciences.org/articles/57436
  52. www.mdpi.com www.mdpi.com
    Characterizing CDK8/19 Inhibitors through a NFκB-Dependent Cell-Based Assay
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    mdpi.com/2073-4409/8/10/1208/htm
  53. elifesciences.org elifesciences.org
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    elifesciences.org/articles/39380
  54. elifesciences.org elifesciences.org
    The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins
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    elifesciences.org/articles/48469
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14604
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    Regulation of Glucose-Dependent Golgi-Derived Microtubules by cAMP/EPAC2 Promotes Secretory Vesicle Biogenesis in Pancreatic β Cells
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    Inhibition of Hsp70 Suppresses Neuronal Hyperexcitability and Attenuates Epilepsy by Enhancing A-Type Potassium Current
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    sciencedirect.com/science/article/pii/S2211124718319624
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    Oral administration of a new HRI activator as a new strategy to improve high‐fat‐diet‐induced glucose intolerance, hepatic steatosis, and hypertriglyceridaemia through FGF21
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14678
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    academic.oup.com/endo/article/158/9/3004/3869384
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    Treprostinil reduces mitochondrial injury during rat renal ischemia-reperfusion injury
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    sciencedirect.com/science/article/pii/S0753332221006946
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    Morphological profiling of human T and NK lymphocytes by high-content cell imaging
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    sciencedirect.com/science/article/pii/S221112472100694X
  63. Jun 2021
  64. link.springer.com link.springer.com
    The voltage-gated proton channel Hv1 promotes microglia-astrocyte communication and neuropathic pain after peripheral nerve injury
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    link.springer.com/article/10.1186/s13041-021-00812-8
  65. www.frontiersin.org www.frontiersin.org
    Treponema denticola-Induced RASA4 Upregulation Mediates Cytoskeletal Dysfunction and MMP-2 Activity in Periodontal Fibroblasts
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    frontiersin.org/article/10.3389/fcimb.2021.671968/full
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    The CD44/COL17A1 pathway promotes the formation of multilayered, transformed epithelia
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    sciencedirect.com/science/article/pii/S0960982221006254
  67. www.mdpi.com www.mdpi.com
    Partial Rescue of F508del-CFTR Stability and Trafficking Defects by Double Corrector Treatment
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    mdpi.com/1422-0067/22/10/5262
  68. May 2021
  69. www.sciencedirect.com www.sciencedirect.com
    Membraneless condensates by Rapsn phase separation as a platform for neuromuscular junction formation
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    sciencedirect.com/science/article/pii/S0896627321002877
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Limited inhibition of multiple nodes in a driver network blocks metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8128439/
  71. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Noise-induced hippocampal oxidative imbalance and aminoacidergic neurotransmitters alterations in developing male rats: Influence of enriched environment during adolescence
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    onlinelibrary.wiley.com/doi/10.1002/dneu.22806
  72. www.sciencedirect.com www.sciencedirect.com
    Human telomerase is directly regulated by non-telomeric TRF2-G-quadruplex interaction
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    sciencedirect.com/science/article/pii/S2211124721004964
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    The E3 ligase TRAF4 Promotes IGF Signaling by Mediating Atypical Ubiquitination of IRS-1
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    sciencedirect.com/science/article/pii/S0021925821005287
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    Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation
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  75. journals.physiology.org journals.physiology.org
    Increased cholinergic activity under conditions of low estrogen leads to adverse cardiac remodeling
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    journals.physiology.org/doi/abs/10.1152/ajpcell.00142.2020
  76. www.sciencedirect.com www.sciencedirect.com
    Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells
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    A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade
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    sciencedirect.com/science/article/pii/S1097276520306122
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    Epigenetic Regulation of DNA Repair Pathway Choice by MacroH2A1 Splice Variants Ensures Genome Stability
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  79. Apr 2021
  80. www.sciencedirect.com www.sciencedirect.com
    NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion
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    sciencedirect.com/science/article/pii/S1550413120305544
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    A Method for Conditional Regulation of Protein Stability in Native or Near-Native Form
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    sciencedirect.com/science/article/pii/S2451945620303767
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    Mechanistic Studies of the Multiple Myeloma and Melanoma Cell-Selective Toxicity of the Rpn13-Binding Peptoid KDT-11
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    sciencedirect.com/science/article/pii/S2451945620303056
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    Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190
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    ATP Synthase c-Subunit Leak Causes Aberrant Cellular Metabolism in Fragile X Syndrome
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    sciencedirect.com/science/article/pii/S0092867420308734
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endoplasmic reticulum oxidoreductase 1 alpha modulates prostate cancer hallmarks
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    ncbi.nlm.nih.gov/pmc/articles/PMC8039598/
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    A selective p53 activator and anticancer agent to improve colorectal cancer therapy
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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optogenetic activation of spinal microglia triggers chronic pain in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC8011727/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC7968844/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alamandine enhances cardiomyocyte contractility in hypertensive rats through a nitric oxide-dependent activation of CaMKII
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    ncbi.nlm.nih.gov/pmc/articles/PMC7191420/
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    RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesis
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    sciencedirect.com/science/article/pii/S1534580721002033
  91. Mar 2021
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    A genome-wide CRISPR screen identifies UFMylation and TRAMP-like complexes as host factors required for hepatitis A virus infection
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    sciencedirect.com/science/article/pii/S221112472100173X
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    Itaconate confers tolerance to late NLRP3 inflammasome activation
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    Alternative lengthening of telomeres is a self-perpetuating process in ALT-associated PML bodies
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    sciencedirect.com/science/article/pii/S1097276520309515
  95. Feb 2021
  96. link.springer.com link.springer.com
    Selective targeting of the androgen receptor-DNA binding domain by the novel antiandrogen SBF-1 and inhibition of the growth of prostate cancer cells
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    link.springer.com/article/10.1007/s10637-020-01050-w
  97. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14887
  98. Jan 2021
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    FOS licenses early events in stem cell activation driving skeletal muscle regeneration
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    sciencedirect.com/science/article/pii/S2211124720316454
  100. Dec 2020
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    Intronic Determinants Coordinate Charme lncRNA Nuclear Activity through the Interaction with MATR3 and PTBP1
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  102. www.cell.com www.cell.com
    Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses
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    cell.com/cell/abstract/S0092-8674(20)31626-3
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    Nuclear cGAS Functions Non-canonically to Enhance Antiviral Immunity via Recruiting Methyltransferase Prmt5
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  104. www.cell.com www.cell.com
    The Aurora-A/TPX2 Axis Directs Spindle Orientation in Adherent Human Cells by Regulating NuMA and Microtubule Stability
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