367 Matching Annotations
  1. Sep 2021
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    FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington’s disease
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    sciencedirect.com/science/article/pii/S2211124721010925
  3. Aug 2021
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    Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity
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    sciencedirect.com/science/article/pii/S1097276521006249
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    Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility
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    sciencedirect.com/science/article/pii/S1534580721005980
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    Molecular and cellular basis of hyperassembly and protein aggregation driven by a rare pathogenic mutation in DDX3X
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    ncbi.nlm.nih.gov/pmc/articles/PMC8335631/
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    UbiB proteins regulate cellular CoQ distribution in Saccharomyces cerevisiae
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    nature.com/articles/s41467-021-25084-7
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    elifesciences.org/articles/37881
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    ncbi.nlm.nih.gov/pmc/articles/PMC6310992/
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    Investigation of Ldb19/Art1 localization and function at the late Golgi
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    ncbi.nlm.nih.gov/pmc/articles/PMC6221343/
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    GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils
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    jneurosci.org/content/37/47/11485
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    O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
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  15. Jul 2021
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    KSHV-encoded vCyclin can modulate HIF1α levels to promote DNA replication in hypoxia
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    elifesciences.org/articles/57436
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    cindr, the Drosophila Homolog of the CD2AP Alzheimer’s Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis
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    Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore Expansion
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    sciencedirect.com/science/article/pii/S0960982218313356
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    Proline-arginine poly-dipeptide encoded by the C9orf72 repeat expansion inhibits adenosine deaminase acting on RNA
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    Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling
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    The Mammalian Malonyl-CoA Synthetase ACSF3 Is Required for Mitochondrial Protein Malonylation and Metabolic Efficiency
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    GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils
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    A Viral Receptor Complementation Strategy to Overcome CAV-2 Tropism for Efficient Retrograde Targeting of Neurons
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    Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation
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    Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity
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    The optineurin/TIA1 pathway inhibits aberrant stress granule formation and reduces ubiquitinated TDP-43
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  32. Jun 2021
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    ASPM promotes homologous recombination-mediated DNA repair by safeguarding BRCA1 stability
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  34. May 2021
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    UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model
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    Carbonic anhydrase 8 (Car8) negatively regulates GLP-1 secretion from enteroendocrine cells in response to long-chain fatty acids
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    TBK1-Mediated DRP1 Targeting Confers Nucleic Acid Sensing to Reprogram Mitochondrial Dynamics and Physiology
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    Proline Hydroxylation Primes Protein Kinases for Autophosphorylation and Activation
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    Ectosomal PKM2 Promotes HCC by Inducing Macrophage Differentiation and Remodeling the Tumor Microenvironment
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    A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation
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    The USP7-TRIM27 axis mediates non-canonical PRC1.1 function and is a druggable target in leukemia
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    TMPRSS11a is a novel age‐altered, tissue specific regulator of migration and wound healing
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    Tyrosine Phosphorylation of the Myosin Regulatory Light Chain Controls Non-muscle Myosin II Assembly and Function in Migrating Cells
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    SAS-6 Association with γ-Tubulin Ring Complex Is Required for Centriole Duplication in Human Cells
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  45. Apr 2021
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    Di-methylation of CD147-K234 Promotes the Progression of NSCLC by Enhancing Lactate Export
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    Revealing the Activity of Trimeric G-proteins in Live Cells with a Versatile Biosensor Design
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    Mutant p53 suppresses innate immune signaling to promote tumorigenesis
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    Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer
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    A protocol for in vivo analysis of liver tumorigenesis in mice using sleeping beauty transposon system
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    cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing
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    Diverse nitrogen signals activate convergent ROP2-TOR signaling in Arabidopsis
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  53. Mar 2021
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    Purification of micronuclei from cultured cells by flow cytometry
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    DSB repair pathway choice is regulated by recruitment of 53BP1 through cell cycle-dependent regulation of Sp1
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  56. aocs.onlinelibrary.wiley.com aocs.onlinelibrary.wiley.com
    Diacylglycerol Kinase η Activity in Cells Using Protein Myristoylation and Cellular Phosphatidic Acid Sensor
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    aocs.onlinelibrary.wiley.com/doi/10.1002/lipd.12301
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    The tumor suppressor LATS2 reduces v‐Src‐induced membrane blebs in a kinase activity‐independent manner
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    ER-directed TREX1 limits cGAS activation at micronuclei
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  59. Feb 2021
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    Expression of p11 and Heteromeric TASK Channels in Rat Carotid Body Glomus Cells and Nerve Growth Factor–differentiated PC12 Cells - Hidetada Matsuoka, Mieczyslaw Pokorski, Keita Harada, Reiji Yoshimura, Masumi Inoue, 2020
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  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ttm50 facilitates calpain activation by anchoring it to calcium stores and increasing its sensitivity to calcium
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    ncbi.nlm.nih.gov/pmc/articles/PMC8115179/
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    Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins
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    Srsf10 and the minor spliceosome control tissue-specific and dynamic SR protein expression
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    Phase separation-mediated condensation of Whirlin-Myo15-Eps8 stereocilia tip complex
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  65. Jan 2021
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    Expression of miRNA-29 in Pancreatic β Cells Promotes Inflammation and Diabetes via TRAF3
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    Failure to Degrade CAT-Tailed Proteins Disrupts Neuronal Morphogenesis and Cell Survival
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  68. Dec 2020
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    Functional inhibition of heat shock protein 70 by VER‐155008 suppresses pleural mesothelioma cell proliferation via an autophagy mechanism
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    A Hemidesmosome-to-Cytoplasm Translocation of Small Heat Shock Proteins Provides Immediate Protection against Heat Stress
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  71. Nov 2020
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    A Selective Autophagy Pathway for Phase-Separated Endocytic Protein Deposits
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    GDF6-CD99 Signaling Regulates Src and Ewing Sarcoma Growth
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  74. Oct 2020
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    Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer
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    ESCRT machinery plays a role in microautophagy in yeast
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  77. Sep 2020
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    FOXK1 Participates in DNA Damage Response by Controlling 53BP1 Function
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    Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions
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    N‐linked glycosylation of the mGlu7 receptor regulates the forward trafficking and transsynaptic interaction with Elfn1
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    TBC1D5-Catalyzed Cycling of Rab7 Is Required for Retromer-Mediated Human Papillomavirus Trafficking during Virus Entry
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    Virus-Mediated Suppression of the Antigen Presentation Molecule MR1
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    Coordinated Ras and Rac Activity Shapes Macropinocytic Cups and Enables Phagocytosis of Geometrically Diverse Bacteria
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    Slo2 potassium channel function depends on RNA editing-regulated expression of a SCYL1 protein
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    Generation and Profiling of 2,135 Human ESC Lines for the Systematic Analyses of Cell States Perturbed by Inducing Single Transcription Factors
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    PP2A promotes ESCRT-0 complex formation on vacuolar membranes and microautophagy induction after TORC1 inactivation
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    Deamidation Shunts RelA from Mediating Inflammation to Aerobic Glycolysis
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    Topological Adaptation of Transmembrane Domains to the Force-Modulated Lipid Bilayer Is a Basis of Sensing Mechanical Force
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    Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain
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    Phosphorylation-Regulated Activation of the Arabidopsis RRS1-R/RPS4 Immune Receptor Complex Reveals Two Distinct Effector Recognition Mechanisms
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    A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation
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    Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome Instability
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    Shank2 Binds to aPKC and Controls Tight Junction Formation with Rap1 Signaling during Establishment of Epithelial Cell Polarity
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    Replicational Dilution of H3K27me3 in Mammalian Cells and the Role of Poised Promoters
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    BRCA1 Mutational Complementation Induces Synthetic Viability
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    C3G localizes to mother centriole dependent on cenexin, and regulates centrosome duplication and primary cilia length
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    WAPL-Dependent Repair of Damaged DNA Replication Forks Underlies Oncogene-Induced Loss of Sister Chromatid Cohesion
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