317 Matching Annotations
  1. Last 7 days
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    ARF alters PAF1 complex integrity to selectively repress oncogenic transcription programs upon p53 loss
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    sciencedirect.com/science/article/pii/S1097276524008608
  3. Nov 2024
  4. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Targeting ATAD3A Phosphorylation Mediated by TBK1 Ameliorates Senescence-Associated Pathologies
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    TMEM39A and TMEM131 facilitate bulk transport of ECM proteins through large COPII vesicle formation
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    sciencedirect.com/science/article/pii/S167385272400287X
  6. Oct 2024
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    A human organoid drug screen identifies α2-adrenergic receptor signaling as a therapeutic target for cartilage regeneration
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    sciencedirect.com/science/article/pii/S1934590924003151
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    Nucleoporin Nsp1 surveils the phase state of FG-Nups
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    sciencedirect.com/science/article/pii/S2211124724011446
  9. Sep 2024
  10. www.biorxiv.org www.biorxiv.org
    Type-II kinase inhibitors that target Parkinson’s Disease-associated LRRK2
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    biorxiv.org/content/10.1101/2024.09.17.613365v1
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    Development of an adipose-tropic AAV capsid ablating liver tropism
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    sciencedirect.com/science/article/pii/S2589004224021552
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    A TBK1-independent primordial function of STING in lysosomal biogenesis
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    Untitled document
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    sciencedirect.com/science/article/pii/S0969212618304581
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    Purification of micronuclei from cultured cells by flow cytometry
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    sciencedirect.com/science/article/pii/S266616672100085X
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Netrin-1 and UNC5B Cooperate with Integrins to Mediate YAP-Driven Cytostasis
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    Dynamic remodeling of Septin structures fine-tunes myogenic differentiation
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    Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis
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    Pooled endogenous protein tagging and recruitment for systematic profiling of protein function
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  19. Aug 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex
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    Maelstrom Represses Canonical Polymerase II Transcription within Bi-Directional piRNA Clusters in Drosophila melanogaster
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    The divergent effects of G3BP orthologs on human stress granule assembly imply a centric role for the core protein interaction network
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    Oxidative stress reprograms the transcriptional coactivator Yki to suppress cell proliferation
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  24. www.molbiolcell.org www.molbiolcell.org
    Ca<sup>2+</sup> entry through mechanotransduction channels localizes BAIAP2L2 to stereocilia tips
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  25. www.science.org www.science.org
    SERINC proteins potentiate antiviral type I IFN production and proinflammatory signaling pathways
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  26. Jul 2024
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    A disinhibitory basal forebrain to cortex projection supports sustained attention
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  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A CPF-like phosphatase module links transcription termination to chromatin silencing
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  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ttm50 facilitates calpain activation by anchoring it to calcium stores and increasing its sensitivity to calcium
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  30. www.cell.com www.cell.com
    SART3 reads methylarginine-marked glycine- and arginine-rich motifs
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    cell.com/cell-reports/abstract/S2211-1247(24)00788-5
  31. www.embopress.org www.embopress.org
    The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex
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  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A phosphorylation-controlled switch confers cell cycle-dependent protein relocalization
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  33. Jun 2024
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    A designed ankyrin-repeat protein that targets Parkinson’s disease-associated LRRK2
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  35. May 2024
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    Efficient expansion and CRISPR-Cas9-mediated gene correction of patient-derived hepatocytes for treatment of inherited liver diseases
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    Autophagy preferentially degrades non-fibrillar polyQ aggregates
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    Metabolic regulator ERRγ governs gastric stem cell differentiation into acid-secreting parietal cells
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    The phosphorylation landscape of infection-related development by the rice blast fungus
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    A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1
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  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Wybutosine hypomodification of tRNAphe activates HERVK and impairs neuronal differentiation
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  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of tumor suppressor TMEM127 drives RET-mediated transformation through disrupted membrane dynamics
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      DOI: 10.7554/eLife.89100

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  43. Apr 2024
  44. rupress.org rupress.org
    WW domains form a folded type of nuclear localization signal to guide YAP1 nuclear import
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  45. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2024 - Wang - Differential contributions of G protein‐ or arrestin subtype‐mediated signalling-html.html
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    52.53.155.43/d25c36f4da339833f1e8b168c06cdacd47a35647/British J Pharmacology - 2024 - Wang - Differential contributions of G protein- or arrestin subtype-mediated signalling-html.html
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Statins inhibit protein kinase D (PKD) activation in intestinal cells and prevent PKD1-induced growth of murine enteroids
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      DOI: 10.1152/ajpcell.00286.2022

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  47. Mar 2024
  48. www.sciencedirect.com www.sciencedirect.com
    Molecular determinants and signaling effects of PKA RIα phase separation
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    sciencedirect.com/science/article/pii/S1097276524001849
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    Selective targeting of Plasmodium falciparum Hsp90 disrupts the 26S proteasome
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    Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1
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    Protocol for the isolation of tumor cell-derived extracellular vesicles followed by in vivo metastasis assessment in a murine ovarian cancer model
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    BLMP-1 is a critical temporal regulator of dietary-restriction-induced response in Caenorhabditis elegans
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    Mea6/cTAGE5 cooperates with TRAPPC12 to regulate PTN secretion and white matter development
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    Mutations in the non-catalytic polyproline motif destabilize TREX1 and amplify cGAS-STING signaling
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    Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling
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    Multi-targeted loss of the antigen presentation molecule MR1 during HSV-1 and HSV-2 infection
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    The FANCI/FANCD2 complex links DNA damage response to R-loop regulation through SRSF1-mediated mRNA export
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    Golgi-to-ER retrograde transport prevents premature differentiation of Drosophila type II neuroblasts via Notch-signal-sending daughter cells
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    Prothymosin α accelerates dengue virus-induced thrombocytopenia
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    The circadian regulator PER1 promotes cell reprogramming by inhibiting inflammatory signaling from macrophages
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  65. Nov 2023
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    Dual stop codon suppression in mammalian cells with genomically integrated genetic code expansion machinery
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    p120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP
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    Small proteins modulate ion-channel-like ACD6 to regulate immunity in Arabidopsis thaliana
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    Stress-induced β cell early senescence confers protection against type 1 diabetes
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    Autophagy-mediated control of ribosome homeostasis in oncogene-induced senescence
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  72. Oct 2023
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    Dual agonistic and antagonistic roles of ZC3H18 provide for co-activation of distinct nuclear RNA decay pathways
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    Intrinsically disordered region-mediated condensation of IFN-inducible SCOTIN/SHISA-5 inhibits ER-to-Golgi vesicle transport
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    Molecular mechanism for activation of the 26S proteasome by ZFAND5
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    DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
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  83. Jul 2023
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    Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation
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  86. Jun 2023
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    Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis
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    Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice
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    Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity
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    Btbd11 supports cell-type-specific synaptic function
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  93. May 2023
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  96. Apr 2023
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    Kupffer-cell-derived IL-6 is repurposed for hepatocyte dedifferentiation via activating progenitor genes from injury-specific enhancers
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    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
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    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
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    SLFN5-mediated chromatin dynamics sculpt higher-order DNA repair topology
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    Newly synthesized AIFM1 determines the hypersensitivity of T lymphocytes to STING activation-induced cell apoptosis
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    Non-Oncogene Addiction of KRAS-Mutant Cancers to IL-1&beta; via Versican and Mononuclear IKK&beta;
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    The RNA binding protein RALY suppresses p53 activity and promotes lung tumorigenesis
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    Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway
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    Negative regulation of TREM2-mediated C9orf72 poly-GA clearance by the NLRP3 inflammasome
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    Microtubule-associated proteins MAP7 and MAP7D1 promote DNA double-strand break repair in the G1 cell cycle phase
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    Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control
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    Crk proteins activate the Rap1 guanine nucleotide exchange factor C3G by segregated adaptor-dependent and -independent mechanisms
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    Exploring therapeutic strategies for infantile neuronal axonal dystrophy (INAD/PARK14)
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  118. Jan 2023
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    Functional partitioning of transcriptional regulators by patterned charge blocks
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    The CNC-family transcription factor Nrf3 coordinates the melanogenesis cascade through macropinocytosis and autophagy regulation
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    The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities
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    Host-symbiont interactions in Angomonas deanei include the evolution of a host-derived dynamin ring around the endosymbiont division site
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    Gut microbiota promotes stem cell differentiation through macrophage and mesenchymal niches in early postnatal development
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    Structural insights into caspase ADPR deacylization catalyzed by a bacterial effector and host calmodulin
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    Integrative omics indicate FMRP sequesters mRNA from translation and deadenylation in human neuronal cells
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    Protocol to image and quantify nucleocytoplasmic transport in cultured cells using fluorescent in situ hybridization and a dual reporter system
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    RIPOR2-mediated autophagy dysfunction is critical for aminoglycoside-induced hearing loss
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    An anillin-CIN85-SEPT9 complex promotes intercellular bridge maturation required for successful cytokinesis
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    Ubiquitination and deubiquitination of 4E-T regulate neural progenitor cell maintenance and neurogenesis by controlling P-body formation
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    Protein disulfide isomerase PDI-6 regulates Wnt secretion to coordinate inter-tissue UPRmt activation and lifespan extension in C. elegans
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  143. May 2022
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    Redox-sensitive E2 Rad6 controls cellular response to oxidative stress via K63-linked ubiquitination of ribosomes
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    The Taspase1/Myosin1f-axis regulates filopodia dynamics
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    Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis
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    Caspase cleavage and nuclear retention of the energy sensor AMPK-α1 during apoptosis
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    Retinoic acid-induced protein 14 controls dendritic spine dynamics associated with depressive-like behaviors
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    Expression of p11 and heteromeric TASK channels in mouse adrenal cortical cells and H295R cells
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  150. Apr 2022
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    Hedgehog-responsive PDGFRa(+) fibroblasts maintain a unique pool of alveolar epithelial progenitor cells during alveologenesis
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    Tel2 regulates redifferentiation of bipotential progenitor cells via Hhex during zebrafish liver regeneration
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    Ca2+ entry through mechanotransduction channels localizes BAIAP2L2 to stereocilia tips
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  154. Mar 2022
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    BMI-1 regulates DNA end resection and homologous recombination repair
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    EB1- and EB2-dependent anterograde trafficking of TRPM4 regulates focal adhesion turnover and cell invasion
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    F-box protein FBXO41 plays vital role in arsenic trioxide-mediated autophagic death of cancer cells
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    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
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  160. Feb 2022
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    A phosphoswitch at acinus-serine437 controls autophagic responses to cadmium exposure and neurodegenerative stress
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    The SH2 domain and kinase activity of JAK2 target JAK2 to centrosome and regulate cell growth and centrosome amplification
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  163. Dec 2021
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    Assessing kinetics and recruitment of DNA repair factors using high content screens
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    Direct inhibition of phosphate transport by immune signaling in Arabidopsis
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    Mechano-transduction via the pectin-FERONIA complex activates ROP6 GTPase signaling in Arabidopsis pavement cell morphogenesis
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    Arabidopsis pavement cell morphogenesis requires FERONIA binding to pectin for activation of ROP GTPase signaling
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    A Genetically Encoded Picolyl Azide for Improved Live Cell Copper Click Labeling
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  169. www.embopress.org www.embopress.org
    Single-cell transcriptomics identifies Gadd45b as a regulator of herpesvirus-reactivating neurons
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  170. elifesciences.org elifesciences.org
    Selective sorting of microRNAs into exosomes by phase-separated YBX1 condensates
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  171. Nov 2021
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    Function and molecular mechanism of N-terminal acetylation in autophagy
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  173. Oct 2021
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    ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis
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    Secondary metabolites of Hülle cells mediate protection of fungal reproductive and overwintering structures against fungivorous animals
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    Interactome analysis reveals endocytosis and membrane recycling of EpCAM during differentiation of embryonic stem cells and carcinoma cells
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    Regulation of synapse weakening through interactions of the microtubule associated protein tau with PACSIN1
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  178. Sep 2021
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    Acute brain vascular regeneration occurs via lymphatic transdifferentiation
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    Parasitic modulation of host development by ubiquitin-independent protein degradation
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    Translational control of polyamine metabolism by CNBP is required for Drosophila locomotor function
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    Cyclical phosphorylation of LRAP35a and CLASP2 by GSK3β and CK1δ regulates EB1-dependent MT dynamics in cell migration
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    Characterization of the subunit composition and structure of adult human glycine receptors
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    FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington’s disease
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  185. Aug 2021
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    Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity
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    Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility
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    Molecular and cellular basis of hyperassembly and protein aggregation driven by a rare pathogenic mutation in DDX3X
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  189. www.nature.com www.nature.com
    UbiB proteins regulate cellular CoQ distribution in Saccharomyces cerevisiae
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  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Investigation of Ldb19/Art1 localization and function at the late Golgi
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    GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils
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    O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
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  197. Jul 2021
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    KSHV-encoded vCyclin can modulate HIF1α levels to promote DNA replication in hypoxia
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    cindr, the Drosophila Homolog of the CD2AP Alzheimer’s Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis
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      mouse anti-GFP (B-2) FITC-conjugated

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    The Mammalian Malonyl-CoA Synthetase ACSF3 Is Required for Mitochondrial Protein Malonylation and Metabolic Efficiency
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    A Viral Receptor Complementation Strategy to Overcome CAV-2 Tropism for Efficient Retrograde Targeting of Neurons
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    TBK1-Mediated DRP1 Targeting Confers Nucleic Acid Sensing to Reprogram Mitochondrial Dynamics and Physiology
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    Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer
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    DSB repair pathway choice is regulated by recruitment of 53BP1 through cell cycle-dependent regulation of Sp1
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