95 Matching Annotations
  1. Oct 2025
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    pORF3-driven biogenesis of lipid droplets facilitates HEV infectivity
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  3. Aug 2025
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    NIPSNAP1 and NIPSNAP2 Act as “Eat Me” Signals for Mitophagy
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  5. Jul 2025
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    Functional liver genomics identifies hepatokines promoting wasting in cancer cachexia
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    CRISPR-edited DPSCs constitutively expressing BDNF enhance dentin regeneration in injured teeth
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  8. Feb 2025
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  10. Nov 2024
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    Inhibition of the Notch signal transducer CSL by Pkc53E-mediated phosphorylation to fend off parasitic immune challenge in Drosophila
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  12. Sep 2024
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    A pontine-medullary loop crucial for REM sleep and its deficit in Parkinson’s disease
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    Metabolic regulator ERRγ governs gastric stem cell differentiation into acid-secreting parietal cells
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    The role of age-associated alpha-synuclein aggregation in a conditional transgenic mouse model of Parkinson's disease: Implications for Lewy body formation
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  18. Apr 2024
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    Human P2X7 receptor variants Gly150Arg and Arg276His polymorphisms have differential effects on risk association and cellular functions in pancreatic cancer
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  20. Mar 2024
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    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    A novel GABAergic population in the medial vestibular nucleus maintains wakefulness and gates rapid eye movement sleep
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    Contactin-associated protein-like 2 (CNTNAP2) mutations impair the essential α-secretase cleavages, leading to autism-like phenotypes
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  24. Aug 2023
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    A split-luciferase lysate-based approach to identify small-molecule modulators of phosphatase subunit interactions
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    eIF4E phosphorylation recruits β-catenin to mRNA cap and promotes Wnt pathway translation in dentate gyrus LTP maintenance
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    ARMH3-mediated recruitment of PI4KB directs Golgi-to-endosome trafficking and activation of the antiviral effector STING
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    COP I and II dependent trafficking controls ER-associated degradation in mammalian cells
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    Glycine receptor autoantibody binding to the extracellular domain is independent from receptor glycosylation
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  33. Feb 2023
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    Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle
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    Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair
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  37. Jun 2022
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    A Phytophthora Effector Suppresses Trans-Kingdom RNAi to Promote Disease Susceptibility
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  39. Apr 2022
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    The non-adrenergic imidazoline-1 receptor protein Nischarin is a key regulator of astrocyte glutamate uptake
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  41. Mar 2022
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    Pathogen hijacks programmed cell death signaling by arginine ADPR-deacylization of caspases
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    Development and Validation of Arc Nanobodies: New Tools for Probing Arc Dynamics and Function
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  45. Feb 2022
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    Dual Sensing of Physiologic pH and Calcium by EFCAB9 Regulates Sperm Motility
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  47. Nov 2021
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    HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease
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    Genetically engineered mice for combinatorial cardiovascular optobiology
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  50. Oct 2021
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    An ancient RAB5 governs the formation of additional vacuoles and cell shape in petunia petals
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  52. Aug 2021
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  57. Jul 2021
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    Multiple pairs of allelic MLA immune receptor-powdery mildew AVRA effectors argue for a direct recognition mechanism
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    The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures
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    DFCP1 associates with lipid droplets
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    ZMYND10 functions in a chaperone relay during axonemal dynein assembly
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  64. Apr 2021
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    Golgi apparatus-synthesized sulfated glycosaminoglycans mediate polymerization and activation of the cGAMP sensor STING
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  66. Mar 2021
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    RADX controls RAD51 filament dynamics to regulate replication fork stability
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  68. Feb 2021
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    The ubiquitin ligase Ariadne-1 regulates neurotransmitter release via ubiquitination of NSF
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  70. Dec 2020
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    The ubiquitin ligase RFWD3 is required for translesion DNA synthesis
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  72. Sep 2020
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    Phosphorylation‐dependent osterix degradation negatively regulates osteoblast differentiation
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    Widely Distributed Neurotensinergic Neurons in the Brainstem Regulate NREM Sleep in Mice
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    Mn2+ Directly Activates cGAS and Structural Analysis Suggests Mn2+ Induces a Noncanonical Catalytic Synthesis of 2′3′-cGAMP
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    Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance
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    Autophagy Controls CSL/RBPJκ Stability through a p62/SQSTM1-Dependent Mechanism
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    c-Src controls stability of sprouting blood vessels in the developing retina independently of cell-cell adhesion through focal adhesion assembly
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    Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
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    Wdr47 Controls Neuronal Polarization through the Camsap Family Microtubule Minus-End-Binding Proteins
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    A Metformin-Responsive Metabolic Pathway Controls Distinct Steps in Gastric Progenitor Fate Decisions and Maturation
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  84. Jan 2020
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    MIGA2 Links Mitochondria, the ER, and Lipid Droplets and Promotes De Novo Lipogenesis in Adipocytes
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    Protective roles of carbonic anhydrase 8 in Machado–Joseph Disease
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    Functional Analysis of the Replication Fork Proteome Identifies BET Proteins as PCNA Regulators
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    SNX27-Mediated Recycling of Neuroligin-2 Regulates Inhibitory Signaling
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    Histone Deacetylase SIRT1 Targets Plk2 to Regulate Centriole Duplication
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    Global Analysis of Intercellular Homeodomain Protein Transfer
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    Oligoadenylate-Synthetase-Family Protein OASL Inhibits Activity of the DNA Sensor cGAS during DNA Virus Infection to Limit Interferon Production
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    Multiple pairs of allelic MLA immune receptor-powdery mildew AVRA effectors argue for a direct recognition mechanism
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  99. Nov 2018
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    The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures
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    TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
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    The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress
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    The InR/Akt/TORC1 Growth-Promoting Signaling Negatively Regulates JAK/STAT Activity and Migratory Cell Fate during Morphogenesis
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    Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma
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    Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses
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    Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains
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    The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer
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    Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage
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    An Attachment-Independent Biochemical Timer of the Spindle Assembly Checkpoint
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  113. Nov 2017
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    Overexpression of α‐synuclein in an astrocyte cell line promotes autophagy inhibition and apoptosis
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    β-TrCP1 Is a Vacillatory Regulator of Wnt Signaling
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    Lck/Hck/Fgr-Mediated Tyrosine Phosphorylation Negatively Regulates TBK1 to Restrain Innate Antiviral Responses
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    onlinelibrary.wiley.com/doi/10.1002/cne.23716/full