2,154 Matching Annotations
  1. Sep 2024
  2. www.sciencedirect.com www.sciencedirect.com
    A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib
    2
    1. scibot 04 Sep 2024
      Plasmid #12259

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      Addgene_12259

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    sciencedirect.com/science/article/pii/S2666379124004245
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    CD14 is a decision-maker between Fas-mediated death and inflammation
    1
    1. scibot 04 Sep 2024
      Plasmid 12259

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    sciencedirect.com/science/article/pii/S2211124724010362
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    Pharmacological chaperones restore proteostasis of epilepsy-associated GABAA receptor variants
    1
    1. scibot 04 Sep 2024
      plasmid # 12259

      DOI: 10.1016/j.phrs.2024.107356

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    sciencedirect.com/science/article/pii/S1043661824003013
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    GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant
    2
    1. scibot 04 Sep 2024
      Addgene_12259

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      RRID:Addgene_12259

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    sciencedirect.com/science/article/pii/S1535610824003052
  6. Aug 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting MYC effector functions in pancreatic cancer by inhibiting the ATPase RUVBL1/2
    1
    1. scibot 29 Aug 2024
      Addgene: 12259

      DOI: 10.1136/gutjnl-2023-331519

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    ncbi.nlm.nih.gov/pmc/articles/PMC11347226/
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    Gemcitabine therapeutically disrupts essential SIRT1-mediated p53 repression in atypical teratoid/rhabdoid tumors
    1
    1. scibot 29 Aug 2024
      Addgene: #12259

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    sciencedirect.com/science/article/pii/S266637912400421X
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    MOF-mediated PRDX1 acetylation regulates inflammatory macrophage activation
    1
    1. scibot 29 Aug 2024
      Addgene; Cat# 12259

      DOI: 10.1016/j.celrep.2024.114682

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    sciencedirect.com/science/article/pii/S2211124724010337
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    PD-1 signaling limits expression of phospholipid phosphatase 1 and promotes intratumoral CD8+ T cell ferroptosis
    1
    1. scibot 29 Aug 2024
      Cat# 12259

      DOI: 10.1016/j.immuni.2024.08.003

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    sciencedirect.com/science/article/pii/S1074761324003765
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    Conservation of antiviral systems across domains of life reveals immune genes in humans
    1
    1. scibot 29 Aug 2024
      Addgene_12259

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    sciencedirect.com/science/article/pii/S1931312824002890
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer
    1
    1. scibot 28 Aug 2024
      plasmid_12259

      DOI: 10.1021/acs.jmedchem.3c00671

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    ncbi.nlm.nih.gov/pmc/articles/PMC10641717/
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    Immune suppression by human thymus-derived effector Tregs relies on glucose/lactate-fueled fatty acid synthesis
    1
    1. scibot 27 Aug 2024
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2024.114681

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    sciencedirect.com/science/article/pii/S2211124724010325
  14. www.sciencedirect.com www.sciencedirect.com
    Disruption of nuclear speckle integrity dysregulates RNA splicing in C9ORF72-FTD/ALS
    2
    1. scibot 27 Aug 2024
      Addgene, Cat #12259

      DOI: 10.1016/j.neuron.2024.07.025

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    2. scibot 27 Aug 2024
      Addgene_12259

      DOI: 10.1016/j.neuron.2024.07.025

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    sciencedirect.com/science/article/pii/S0896627324005701
  15. www.sciencedirect.com www.sciencedirect.com
    Engineering acyclovir-induced RNA nanodevices for reversible and tunable control of aptamer function
    1
    1. scibot 27 Aug 2024
      plasmid_12259

      DOI: 10.1016/j.chembiol.2024.07.017

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    sciencedirect.com/science/article/pii/S2451945624003192
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unveiling the oncogenic role of LZTS1 in colorectal cancer
    1
    1. scibot 26 Aug 2024
      psMD2G

      DOI: 10.1111/jcmm.18441

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    ncbi.nlm.nih.gov/pmc/articles/PMC11256987/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ELM2‐SANT Domain‐Containing Scaffolding Protein 1 Regulates Differentiation and Maturation of Cardiomyocytes Derived From Human‐Induced Pluripotent Stem Cells
    1
    1. scibot 26 Aug 2024
      pMD2G

      DOI: 10.1161/JAHA.124.034816

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    ncbi.nlm.nih.gov/pmc/articles/PMC11255699/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation
    1
    1. scibot 26 Aug 2024
      12259

      DOI: 10.1101/2024.07.05.602170

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    ncbi.nlm.nih.gov/pmc/articles/PMC11257429/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficient Genome Editing with Chimeric Oligonucleotide-Directed Editing
    1
    1. scibot 26 Aug 2024
      12259

      DOI: 10.1101/2024.07.09.602710

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    ncbi.nlm.nih.gov/pmc/articles/PMC11257564/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Galectin-3-Binding Protein Inhibits Extracellular Heparan 6-O-Endosulfatase Sulf-2
    1
    1. scibot 26 Aug 2024
      pMD2

      DOI: 10.1016/j.mcpro.2024.100793

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    ncbi.nlm.nih.gov/pmc/articles/PMC11259796/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    De Novo Multi-Omics Pathway Analysis Designed for Prior Data Independent Inference of Cell Signaling Pathways
    1
    1. scibot 26 Aug 2024
      12259

      DOI: 10.1016/j.mcpro.2024.100780

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    ncbi.nlm.nih.gov/pmc/articles/PMC11259815/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-nucleus transcriptomics uncovers a geroprotective role of YAP in primate gingival aging
    1
    1. scibot 26 Aug 2024
      12259

      DOI: 10.1093/procel/pwae017

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    ncbi.nlm.nih.gov/pmc/articles/PMC11259548/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ONECUT2 acts as a lineage plasticity driver in adenocarcinoma as well as neuroendocrine variants of prostate cancer
    1
    1. scibot 26 Aug 2024
      12259

      DOI: 10.1093/nar/gkae547

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    ncbi.nlm.nih.gov/pmc/articles/PMC11260453/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evaluation of DNA minicircles for delivery of adenine and cytosine base editors using activatable gene on “GO” reporter imaging systems
    1
    1. scibot 26 Aug 2024
      12259

      DOI: 10.1016/j.omtn.2024.102248

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    ncbi.nlm.nih.gov/pmc/articles/PMC11260848/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular insights into degron recognition by CRL5ASB7 ubiquitin ligase
    1
    1. scibot 26 Aug 2024
      pMD2

      DOI: 10.1038/s41467-024-50556-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11263391/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP20 deubiquitinates and stabilizes the reticulophagy receptor RETREG1/FAM134B to drive reticulophagy
    1
    1. scibot 26 Aug 2024
      12,259

      DOI: 10.1080/15548627.2024.2347103

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    ncbi.nlm.nih.gov/pmc/articles/PMC11262213/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4
    1
    1. scibot 26 Aug 2024
      pMD2

      DOI: 10.1038/s41467-024-50511-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC11266596/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GDNF/GFRA1 signaling contributes to chemo- and radioresistance in glioblastoma
    1
    1. scibot 26 Aug 2024
      12,259

      DOI: 10.1038/s41598-024-68626-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11292001/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia
    1
    1. scibot 26 Aug 2024
      pMD2

      DOI: 10.1038/s41467-024-51192-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11322655/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The epithelial Na+ channel (ENaC) in ovarian granulosa cells modulates Ca2+ mobilization and gonadotrophin signaling for estrogen homeostasis and female fertility
    1
    1. scibot 26 Aug 2024
      12259

      DOI: 10.1186/s12964-024-01778-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC11323461/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Casein kinase 1α mediates phosphorylation of the Merkel cell polyomavirus large T antigen for β-TrCP destruction complex interaction and subsequent degradation
    1
    1. scibot 26 Aug 2024
      pMD2.G

      DOI: 10.1128/mbio.01117-24

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    ncbi.nlm.nih.gov/pmc/articles/PMC11323502/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A high-throughput microfabricated platform for rapid quantification of metastatic potential
    1
    1. scibot 26 Aug 2024
      pMD.G2

      DOI: 10.1126/sciadv.adk0015

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    ncbi.nlm.nih.gov/pmc/articles/PMC11328906/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translation efficiency covariation across cell types is a conserved organizing principle of mammalian transcriptomes
    1
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      12259

      DOI: 10.1101/2024.08.11.607360

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    ncbi.nlm.nih.gov/pmc/articles/PMC11326257/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SelK promotes glioblastoma cell proliferation by inhibiting β-TrCP1 mediated ubiquitin-dependent degradation of CDK4
    1
    1. scibot 26 Aug 2024
      12,259

      DOI: 10.1186/s13046-024-03157-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11331741/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An i-motif-regulated enhancer, eRNA and adjacent lncRNA affect Lhb expression through distinct mechanisms in a sex-specific context
    1
    1. scibot 26 Aug 2024
      MD2.G

      DOI: 10.1007/s00018-024-05398-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC11335282/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sub-genomic flaviviral RNA elements increase the stability and abundance of recombinant AAV vector transcripts
    1
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      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11334430/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The deubiquitinase OTUD1 stabilizes NRF2 to alleviate hepatic ischemia/reperfusion injury
    1
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      12259

      DOI: 10.1016/j.redox.2024.103287

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    ncbi.nlm.nih.gov/pmc/articles/PMC11340619/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Time-of-day effects of cancer drugs revealed by high-throughput deep phenotyping
    1
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      12259

      DOI: 10.1038/s41467-024-51611-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC11339390/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Gsk3a reverses immune evasion to enhance immunotherapy in hepatocellular carcinoma
    1
    1. scibot 26 Aug 2024
      pMD2.G

      DOI: 10.1136/jitc-2024-009642

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    ncbi.nlm.nih.gov/pmc/articles/PMC11340705/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 screening develops an epigenetic and transcriptional gene signature for risk stratification and target prediction in neuroblastoma
    1
    1. scibot 26 Aug 2024
      pMD2.G

      DOI: 10.3389/fcell.2024.1433008

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    ncbi.nlm.nih.gov/pmc/articles/PMC11338898/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A plug-and-play monofunctional platform for targeted degradation of extracellular proteins and vesicles
    1
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      12259

      DOI: 10.1038/s41467-024-51720-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC11341853/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Specific multivalent molecules boost CRISPR-mediated transcriptional activation
    1
    1. scibot 26 Aug 2024
      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11341856/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Association with TFIIIC limits MYCN localisation in hubs of active promoters and chromatin accumulation of non-phosphorylated RNA polymerase II
    1
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      12259

      DOI: 10.7554/eLife.94407

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    ncbi.nlm.nih.gov/pmc/articles/PMC11343564/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ACAD10 and ACAD11 allow entry of 4-hydroxy fatty acids into β-oxidation
    1
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      12259

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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA variant assessment using transactivation and transdifferentiation
    1
    1. scibot 26 Aug 2024
      12269

      DOI: 10.1016/j.ajhg.2024.06.018

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    ncbi.nlm.nih.gov/pmc/articles/PMC11339655/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lipid synthesis, triggered by PPARγ T166 dephosphorylation, sustains reparative function of macrophages during tissue repair
    1
    1. scibot 26 Aug 2024
      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11343878/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Shifts in receptors during submergence of an encephalitic arbovirus
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      Addgene_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11324528/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular mimicry in multisystem inflammatory syndrome in children
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      plasmid_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11324515/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evolutionary and functional analyses reveal a role for the RHIM in tuning RIPK3 activity across vertebrates
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    1. scibot 26 Aug 2024
      plasmid_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11326134/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel role of NCoR1 in impairing spatial memory through the mediation of a novel interacting protein DEC2
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      plasmid_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11335199/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EZH2 represses mesenchymal genes and upholds the epithelial state of breast carcinoma cells
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  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumoral Interferon Beta Induces an Immune-Stimulatory Phenotype in Tumor-Associated Macrophages in Melanoma Brain Metastases
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      RRID# Addgene_12259

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  53. www.sciencedirect.com www.sciencedirect.com
    CRISPR screening identifies PRMT1 as a key pro-ferroptotic gene via a two-layer regulatory mechanism
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    sciencedirect.com/science/article/pii/S2211124724010131
  54. www.sciencedirect.com www.sciencedirect.com
    Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence
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    sciencedirect.com/science/article/pii/S1097276524006609
  55. www.sciencedirect.com www.sciencedirect.com
    RNA interacts with topoisomerase I to adjust DNA topology
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VAMP2 regulates phase separation of α-synuclein
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    ncbi.nlm.nih.gov/pmc/articles/PMC11322000/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The NR4A2/VGF pathway fuels inflammation-induced neurodegeneration via promoting neuronal glycolysis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11324305/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC11329502/
  59. www.sciencedirect.com www.sciencedirect.com
    Acetate enables metabolic fitness and cognitive performance during sleep disruption
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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A spectrum of clinically-identified cysteine mutations in fibulin-3 (EFEMP1) highlight its disulfide bonding complexity and potential to induce stress response activation
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    1. scibot 22 Aug 2024
      plasmid_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11291045/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UM171 suppresses breast cancer progression by inducing KLF2
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      plasmid_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11297059/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The receptor protein tyrosine phosphatase PTPRK promotes intestinal repair and catalysis-independent tumour suppression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11298714/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Programmable Protein Stabilization with Language Model-Derived Peptide Guides
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    ncbi.nlm.nih.gov/pmc/articles/PMC11302690/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EphA3-targeted chimeric antigen receptor T cells are effective in glioma and generate curative memory T cell responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC11308882/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancing homology-directed repair efficiency with HDR-boosting modular ssDNA donor
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    ncbi.nlm.nih.gov/pmc/articles/PMC11315919/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proximity analysis of native proteomes reveals phenotypic modifiers in a mouse model of autism and related neurodevelopmental conditions
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    ncbi.nlm.nih.gov/pmc/articles/PMC11316102/
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human RNA Polymerase II Segregates from Genes and Nascent RNA and Transcribes in the Presence of DNA-Bound dCas9
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    1. scibot 22 Aug 2024
      plasmid_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11312690/
  68. www.embopress.org www.embopress.org
    Satellite cell-derived TRIM28 is pivotal for mechanical load- and injury-induced myogenesis
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    embopress.org/doi/10.1038/s44319-024-00227-1
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Local monomer levels and established filaments potentiate non-muscle myosin 2 assembly
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    1. scibot 22 Aug 2024
      Plasmid_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC10866686/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    YTHDC1 m6A-dependent and m6A-independent functions converge to preserve the DNA damage response
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    1. scibot 21 Aug 2024
      pMD2.G

      DOI: 10.1038/s44318-024-00153-x

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  71. www.sciencedirect.com www.sciencedirect.com
    Protocol for establishing inducible CRISPRd system for blocking transcription factor-binding sites in human pluripotent stem cells
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    sciencedirect.com/science/article/pii/S2666166724003988
  72. www.sciencedirect.com www.sciencedirect.com
    The SW480 cell line as a model of resident and migrating colon cancer stem cells
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    sciencedirect.com/science/article/pii/S2589004224018832
  73. www.sciencedirect.com www.sciencedirect.com
    Prior Fc receptor activation primes macrophages for increased sensitivity to IgG via long-term and short-term mechanisms
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      DOI: 10.1016/j.devcel.2024.07.017

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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SFTSV nucleoprotein mediates DNA sensor cGAS degradation to suppress cGAS-dependent antiviral responses
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      DOI: 10.1128/spectrum.03796-23

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  75. www.sciencedirect.com www.sciencedirect.com
    Nuclear PKM2 binds pre-mRNA at folded G-quadruplexes and reveals their gene regulatory role
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  76. www.sciencedirect.com www.sciencedirect.com
    The divergent effects of G3BP orthologs on human stress granule assembly imply a centric role for the core protein interaction network
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  77. www.cell.com www.cell.com
    SYNGAP1 deficiency disrupts synaptic neoteny in xenotransplanted human cortical neurons in vivo
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      DOI: 10.1016/j.neuron.2024.07.007

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    cell.com/neuron/abstract/S0896-6273(24)00529-4
  78. www.sciencedirect.com www.sciencedirect.com
    Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation
    2
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    sciencedirect.com/science/article/pii/S1097276524005896
  79. www.sciencedirect.com www.sciencedirect.com
    Protocol for the application of single-cell damage in murine intestinal organoid models
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  80. www.sciencedirect.com www.sciencedirect.com
    Protocol for establishing inducible CRISPR interference system for multiple-gene silencing in human pluripotent stem cells
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    1. scibot 19 Aug 2024
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  81. www.sciencedirect.com www.sciencedirect.com
    Purinosomes spatially co-localize with mitochondrial transporters
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      DOI: 10.1016/j.jbc.2024.107620

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    sciencedirect.com/science/article/pii/S0021925824021215
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor-derived GLI1 promotes remodeling of the immune tumor microenvironment in melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11295348/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Crosstalk of MAP3K1 and EGFR signaling mediates gene-environment interactions that block developmental tissue closure
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    ncbi.nlm.nih.gov/pmc/articles/PMC11294703/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Construction of an IFNAR1 knockout MDBK cell line using CRISPR/Cas9 and its effect on bovine virus replication
    1
    1. scibot 18 Aug 2024
      pMD2.G

      DOI: 10.3389/fimmu.2024.1404649

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    ncbi.nlm.nih.gov/pmc/articles/PMC11294105/
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimized reporters for multiplexed detection of transcription factor activity
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      12259

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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Peptidylarginine deiminase 3 modulates response to neratinib in HER2 positive breast cancer
    1
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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting fatty acid oxidation enhances response to HER2-targeted therapy
    1
    1. scibot 18 Aug 2024
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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TERT upstream promoter methylation regulates TERT expression and acts as a therapeutic target in TERT promoter mutation-negative thyroid cancer
    1
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic transcriptome profiling of hPSC-derived osteoblasts unveils CORIN's mastery in governing osteogenesis through CEBPD modulation
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    1. scibot 18 Aug 2024
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Colchicine-mediated selective autophagic degradation of HBV core proteins inhibits HBV replication and HBV-related hepatocellular carcinoma progression
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    1. scibot 18 Aug 2024
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  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrative genomics identifies SHPRH as a tumor suppressor gene in lung adenocarcinoma that regulates DNA damage response
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exome-wide association study identifies KDELR3 mutations in extreme myopia
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    1. scibot 18 Aug 2024
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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol for transducing human primary epithelial prostate cells and patient-derived organoids with high efficiency
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    1. scibot 18 Aug 2024
      Addgene_12259

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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo single-cell CRISPR uncovers distinct TNF programmes in tumour evolution
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      12259

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  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Circular RNAs regulate neuron size and migration of midbrain dopamine neurons during development
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    1. scibot 18 Aug 2024
      12259

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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone-methyltransferase KMT2D deficiency impairs the Fanconi anemia/BRCA pathway upon glycolytic inhibition in squamous cell carcinoma
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    1. scibot 18 Aug 2024
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  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Latrophilin-2 mediates fluid shear stress mechanotransduction at endothelial junctions
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    1. scibot 18 Aug 2024
      RRID:Addgene_12259

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  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The BET PROTAC inhibitor GNE-987 displays anti-tumor effects by targeting super-enhancers regulated gene in osteosarcoma
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      RRID:Addgene_12259

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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-catenin mediates endodermal commitment of human ES cells via distinct transactivation functions
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      Addgene_12259

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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Altered ribosomal profile in acquired resistance and reversal associates with pathological response to chemotherapy in inflammatory breast cancer
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      plasmid_12259

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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMARCA4 controls state plasticity in small cell lung cancer through regulation of neuroendocrine transcription factors and REST splicing
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      Addgene_12259

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  102. 52.53.155.43 52.53.155.43
    Modeling of Intracellular Taurine Levels Associated with Ovarian Cancer Reveals Activation of p53, ERK, mTOR and DNA-Damage-Sensing-Dependent Cell Protection
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      Addgene_12259

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  103. www.sciencedirect.com www.sciencedirect.com
    Viral hijacking of hnRNPH1 unveils a G-quadruplex-driven mechanism of stress control
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      RRID:Addgene_12259

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    sciencedirect.com/science/article/pii/S1931312824002658
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD177 is a novel IgG Fc receptor and CD177 genetic variants affect IgG-mediated function
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      DOI: 10.3389/fimmu.2024.1418539

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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CHD4 R975H mutant activates tumorigenic pathways and promotes stemness and M2-like macrophage polarization in endometrial cancer
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      12259

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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting monocytic Occludin impairs transendothelial migration and HIV neuroinvasion
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      12259

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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Derlin-1-Stat5b axis maintains homeostasis of adult hippocampal neurogenesis
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      12259

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  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The IRE1α/XBP1 signaling axis drives myoblast fusion in adult skeletal muscle
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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Strong capacity of differentiated PD-L1 CAR-modified UCB-CD34+ cells and PD-L1 CAR-modified UCB-CD34+-derived NK cells in killing target cells and restoration of the anti-tumor function of PD-1-high exhausted T Cells
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      pMD2G

      DOI: 10.1186/s13287-024-03871-5

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  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LACTB suppresses liver cancer progression through regulation of ferroptosis
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      pMD2. G

      DOI: 10.1016/j.redox.2024.103270

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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NS1-mediated enhancement of MVC transcription and replication promoted by KAT5/H4K12ac
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      pMD2.G

      DOI: 10.1128/jvi.01695-23

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  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tight Junction Component Occludin Binds to FIP5 to Regulate Endosome Trafficking and Mitotic Spindle Function
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  113. www.biorxiv.org www.biorxiv.org
    Replicative senescence is ATM driven, reversible, and accelerated by hyperactivation of ATM at normoxia
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    1. scibot 16 Aug 2024
      pMD2

      DOI: 10.1101/2024.06.24.600514

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  114. www.sciencedirect.com www.sciencedirect.com
    A primate-specific endogenous retroviral envelope protein sequesters SFRP2 to regulate human cardiomyocyte development
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    1. scibot 15 Aug 2024
      Cat# 12259

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  115. www.sciencedirect.com www.sciencedirect.com
    OPA1 promotes ferroptosis by augmenting mitochondrial ROS and suppressing an integrated stress response
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      Cat# 12259

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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability
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      Cat# 12259

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  117. www.biorxiv.org www.biorxiv.org
    An enhanced Eco1 retron editor enables precision genome engineering in human cells from a single-copy integrated lentivirus
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    1. scibot 14 Aug 2024
      Addgene #12259

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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitophagy defect mediates the aging‐associated hallmarks in Hutchinson–Gilford progeria syndrome
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating Point Mutations in the MET Kinase Domain Represent a Unique Molecular Subset of Lung Cancer and Other Malignancies Targetable with MET Inhibitors
    1
    1. scibot 13 Aug 2024
      pMD2.G

      DOI: 10.1158/2159-8290.CD-23-1217

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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting RBM39 through indisulam induced mis-splicing of mRNA to exert anti-cancer effects in T-cell acute lymphoblastic leukemia
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      12259

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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Olanzapine suppresses mPFC activity-norepinephrine releasing to alleviate CLOCK-enhanced cancer stemness under chronic stress
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      12259

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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cathepsin L induces cellular senescence by upregulating CUX1 and p16INK4a
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      12259

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  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 Accessory Protein ORF8 Targets the Dimeric IgA Receptor pIgR
    1
    1. scibot 13 Aug 2024
      12260

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  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP9X inhibits metastasis in pulmonary sarcomatoid carcinoma by regulating epithelial-mesenchymal transition, angiogenesis and immune infiltration
    1
    1. scibot 13 Aug 2024
      pMD2.G

      DOI: 10.1016/j.tranon.2024.101950

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  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced adipocyte glutaminase activity promotes energy expenditure and metabolic health
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      12259

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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A deep learning model of tumor cell architecture elucidates response and resistance to CDK4/6 inhibitors
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    1. scibot 13 Aug 2024
      12259

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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Harnessing DNA replication stress to target RBM10 deficiency in lung adenocarcinoma
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      12259

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  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemoproteomic development of SLC15A4 inhibitors with anti-inflammatory activity
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    1. scibot 13 Aug 2024
      12259

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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuronal MAPT expression is mediated by long-range interactions with cis-regulatory elements
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  130. www.cell.com www.cell.com
    The splicing factor CCAR1 regulates the Fanconi anemia/BRCA pathway
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      Addgene# 12259

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    cell.com/molecular-cell/fulltext/S1097-2765(24)00538-0
  131. www.cell.com www.cell.com
    Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma
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      Addgene: 12259

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    cell.com/cell-reports/fulltext/S2211-1247(24)00678-8
  132. www.cell.com www.cell.com
    Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport
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      RRID: Addgene_12259

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  133. www.cell.com www.cell.com
    Early rhombic lip Protogenin+ve stem cells in a human-specific neurovascular niche initiate and maintain group 3 medulloblastoma
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    cell.com/cell/fulltext/S0092-8674(24)00651-2
  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nuclear rupture induced by capillary constriction forces promotes differential effects on metastatic and normal breast cells
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      MD2.G

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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Polyomavirus ALTOs, but not MTs, downregulate viral early gene expression by activating the NF-κB pathway
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      12259

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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conserved role of hnRNPL in alternative splicing of epigenetic modifiers enables B cell activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11169469/
  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of an Immunodominant B-Cell Epitope in African Swine Fever Virus p30 Protein and Evidence of p30 Antibody-Mediated Antibody Dependent Cellular Cytotoxicity
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      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11125664/
  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exogenous Metabolic Modulators Improve Response to Carboplatin in Triple-Negative Breast Cancer
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      PMD2.G

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    ncbi.nlm.nih.gov/pmc/articles/PMC11119195/
  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of TSC2 lysosome translocation and mitochondrial turnover by TSC2 acetylation status
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    ncbi.nlm.nih.gov/pmc/articles/PMC11143182/
  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PAX6 promotes neuroendocrine phenotypes of prostate cancer via enhancing MET/STAT5A-mediated chromatin accessibility
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      Addgene_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11094950/
  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phospholipase PLA2G7 is complementary to GPX4 in mitigating punicic acid induced ferroptosis in prostate cancer cells
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    2024.04.26.591029v1.full-html.html
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    ncbi.nlm.nih.gov/pmc/articles/PMC11071485/
  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting NRAS via miR-1304-5p or farnesyltransferase inhibition confers sensitivity to ALK inhibitors in ALK-mutant neuroblastoma
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      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11039739/
  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    METTL17 is an Fe-S cluster checkpoint for mitochondrial translation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11046306/
  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    iNOS is necessary for GBP-mediated T. gondii clearance in murine macrophages via vacuole nitration and intravacuolar network collapse
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    ncbi.nlm.nih.gov/pmc/articles/PMC10973475/
  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deletion of Sarcolemmal Membrane-Associated Protein Isoform 3 (SLMAP3) in Cardiac Progenitors Delays Embryonic Growth of Myocardium without Affecting Hippo Pathway
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      https://www.addgene.org/12259/

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    ncbi.nlm.nih.gov/pmc/articles/PMC10932035/
  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Shaping immune landscape of colorectal cancer by cholesterol metabolites
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      PMD.2G

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    ncbi.nlm.nih.gov/pmc/articles/PMC10897227/
  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Host ZCCHC3 blocks HIV-1 infection and production through a dual mechanism
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      Addgene_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC10879702/
  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTBP3/IGF2BP3/HMGA1 axis promotes renal cancer growth and metastasis
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  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic Targeting to Overcome Radioresistance in Head and Neck Cancer
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      pMD2.G

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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TDP-43 chronic deficiency leads to dysregulation of transposable elements and gene expression by affecting R-loop and 5hmC crosstalk
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      12259

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  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intercellular transfer of cancer cell invasiveness via endosome-mediated protease shedding
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    ncbi.nlm.nih.gov/pmc/articles/PMC10858897/
  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Safety and feasibility of anti-CD19 CAR T cells expressing inducible IL-7 and CCL19 in patients with relapsed or refractory large B-cell lymphoma
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      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC10774422/
  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct spatiotemporal dynamics of CD8+ T cell-derived cytokines in the tumor microenvironment
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      12259

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  155. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Direct interrogation of context-dependent GPCR activity with a universal biosensor platform
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  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of anti-tumor immunity by melanoma cell-derived Activin-A depends on STING
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  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineering lentivirus envelope VSV-G for liver targeted delivery of IDOL-shRNA to ameliorate hypercholesterolemia and atherosclerosis
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      pMD2.G

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  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TGFβ and Hippo Signaling Pathways Coordinate to Promote Acinar to Ductal Metaplasia in Human Pancreas
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      Addgene, Watertown, MA, USA, #12259

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  159. aacrjournals.org aacrjournals.org
    EBV-upregulated B7-H3 inhibits NK cell-mediated antitumor function and contributes to nasopharyngeal carcinoma progression
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      RRID: Addgene_12259

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    aacrjournals.org/cancerimmunolres/article/11/6/830/726521/EBV-Upregulated-B7-H3-Inhibits-NK-cell-Mediated
  160. www.researchsquare.com www.researchsquare.com
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  161. www.science.org www.science.org
    Targeted epigenomic editing ameliorates adult anxiety and excessive drinking after adolescent alcohol exposure
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      Addgene #12259

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    science.org/doi/10.1126/sciadv.abn2748
  162. www.science.org www.science.org
    Interpretation of cancer mutations using a multiscale map of protein systems
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  163. www.embopress.org www.embopress.org
    A method for benchmarking genetic screens reveals a predominant mitochondrial bias
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      Cat #12259

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  164. www.mdpi.com www.mdpi.com
    Role of Decorin in Posterior Capsule Opacification and Eye Lens Development
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  165. www.cell.com www.cell.com
    Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1
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      Cat# 12259

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    cell.com/molecular-cell/fulltext/S1097-2765(20)30802-9
  166. www.cell.com www.cell.com
    Live Imaging Reveals Listeria Hijacking of E-Cadherin Recycling as It Crosses the Intestinal Barrier
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    cell.com/current-biology/fulltext/S0960-9822(20)31753-X
  167. journals.asm.org journals.asm.org
    A Generic, Scalable, and Rapid Time-Resolved Förster Resonance Energy Transfer-Based Assay for Antigen Detection—SARS-CoV-2 as a Proof of Concept | mBio
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      RRID:Addgene_12259

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  168. www.sciencedirect.com www.sciencedirect.com
    The V-ATPase/ATG16L1 axis is controlled by the V1H subunit
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  169. www.nature.com www.nature.com
    Deubiquitinase USP9x regulates the proline biosynthesis pathway in non-small cell lung cancer
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      RRID:Addgene_12259

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  170. Jul 2024
  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Initial Characterization of WDR5B Reveals a Role in the Proliferation of Retinal Pigment Epithelial Cells
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    1. scibot 31 Jul 2024
      pMD2.G

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  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developing Device of Death Operation (DODO) to Detect Apoptosis in 2D and 3D Cultures
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  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucocorticoid receptor controls atopic dermatitis inflammation via functional interactions with P63 and autocrine signaling in epidermal keratinocytes
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    1. scibot 31 Jul 2024
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  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Helicobacter pylori-Induced Decrease in Membrane Expression of Na,K-ATPase Leads to Gastric Injury
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    1. scibot 31 Jul 2024
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  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiscale biophysical analysis of nucleolus disassembly during mitosis
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  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A genome-wide CRISPR/Cas9 screen identifies calreticulin as a selective repressor of ATF6α
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    1. scibot 31 Jul 2024
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  177. www.sciencedirect.com www.sciencedirect.com
    On the role of p53 in the cellular response to aneuploidy
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    1. scibot 30 Jul 2024
      RRID:Addgene_12259

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  178. www.biorxiv.org www.biorxiv.org
    Resistance of estrogen receptor function to BET bromodomain inhibition is mediated by transcriptional coactivator cooperativity
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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DCAF16-Based Covalent Handle for the Rational Design of Monovalent Degraders
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  180. www.sciencedirect.com www.sciencedirect.com
    Polysome collapse and RNA condensation fluidize the cytoplasm
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  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VHL loss enhances antitumor immunity by activating the anti-viral DNA-sensing pathway
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  182. www.sciencedirect.com www.sciencedirect.com
    ATAD1 prevents clogging of TOM and damage caused by un-imported mitochondrial proteins
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  183. www.sciencedirect.com www.sciencedirect.com
    Myeloid cells coordinately induce glioma cell-intrinsic and cell-extrinsic pathways for chemoresistance via GP130 signaling
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  184. www.sciencedirect.com www.sciencedirect.com
    Renal protection after hemorrhagic shock in rats: Possible involvement of SUMOylation
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hsp47 promotes biogenesis of multi-subunit neuroreceptors in the endoplasmic reticulum
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  186. www.sciencedirect.com www.sciencedirect.com
    Sterol-like drugs potentiate statin-triggered prostate cancer cell death by inhibiting SREBP2 nuclear translocation
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  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol to identify defined reprogramming factor expression using a factor-indexing single-nuclei multiome sequencing approach
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  188. www.embopress.org www.embopress.org
    DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer
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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer
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  190. www.nature.com www.nature.com
    CREB1 promotes expression of immune checkpoint HLA-E leading to immune escape in multiple myeloma
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  191. www.sciencedirect.com www.sciencedirect.com
    Interface-guided phenotyping of coding variants in the transcription factor RUNX1
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    sciencedirect.com/science/article/pii/S2211124724007654
  192. www.sciencedirect.com www.sciencedirect.com
    Leveraging a self-cleaving peptide for tailored control in proximity labeling proteomics
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  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling
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  194. 52.53.155.43 52.53.155.43
    1-s2.0-S2211124724007770-mmc1-html.html
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  195. www.sciencedirect.com www.sciencedirect.com
    Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome
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  196. www.cell.com www.cell.com
    SART3 reads methylarginine-marked glycine- and arginine-rich motifs
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    cell.com/cell-reports/abstract/S2211-1247(24)00788-5
  197. www.cell.com www.cell.com
    Spontaneous and evoked synaptic vesicle release arises from a single releasable pool
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  198. www.biorxiv.org www.biorxiv.org
    BRAT1 - a new therapeutic target for glioblastoma
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      DOI: 10.1101/2024.07.08.602519

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