387 Matching Annotations
  1. Jun 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic movement of the Golgi unit and its glycosylation enzyme zones
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    ncbi.nlm.nih.gov/pmc/articles/PMC11130159/
  3. May 2024
  4. www.biorxiv.org www.biorxiv.org
    Spatiotemporal proteomics reveals the biosynthetic lysosomal membrane protein interactome in neurons
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    biorxiv.org/content/10.1101/2024.05.16.594502v1
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficiency of UCHL1 results in insufficient decidualization accompanied by impaired dNK modulation and eventually miscarriage
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11103838/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    METTL8 links mt-tRNA m3C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11093979/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxia-induced NOS1 as a therapeutic target in hypercholesterolemia-related colorectal cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11100240/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mecp2 fine-tunes quiescence exit by targeting nuclear receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11095939/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CYB561 supports the neuroendocrine phenotype in castration-resistant prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11090301/
  10. www.sciencedirect.com www.sciencedirect.com
    USP7 promotes IgA class switching through stabilizing RUNX3 for germline transcription activation
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    sciencedirect.com/science/article/pii/S2211124724005229
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DDX18 Facilitates the Tumorigenesis of Lung Adenocarcinoma by Promoting Cell Cycle Progression through the Upregulation of CDK4
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    ncbi.nlm.nih.gov/pmc/articles/PMC11084921/
  12. 52.53.155.43 52.53.155.43
    TERC promotes non-small cell lung cancer progression by facilitating the nuclear localization of TERT
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    52.53.155.43/761c70660e3a03a822484173742c13c4c44cc6bf/PIIS2589004224010915-html.html
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of proteoglycan synthesis genes in osteosarcoma stem cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11058990/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRRX1-TOP2A interaction is a malignancy-promoting factor in human malignant peripheral nerve sheath tumours
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    ncbi.nlm.nih.gov/pmc/articles/PMC11058259/
  15. Apr 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined SNPs sequencing and allele specific proteomics capture reveal functional causality underpinning the 2p25 prostate cancer susceptibility locus
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    ncbi.nlm.nih.gov/pmc/articles/PMC11030545/
  17. www.pnas.org www.pnas.org
    NOVA1 acts as an oncogenic RNA-binding protein to regulate cholesterol homeostasis in human glioblastoma cells
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    pnas.org/doi/abs/10.1073/pnas.2314695121
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation by the RNA-binding protein Unkempt at its effector interface
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    ncbi.nlm.nih.gov/pmc/articles/PMC11009413/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An EBV-related CD4 TCR immunotherapy inhibits tumor growth in an HLA-DP5+ nasopharyngeal cancer mouse model
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11014665/
  20. www.embopress.org www.embopress.org
    PRODH safeguards human naive pluripotency by limiting mitochondrial oxidative phosphorylation and reactive oxygen species production
    1
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    embopress.org/doi/full/10.1038/s44319-024-00110-z
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lysophosphatidic acid down-regulates human RIPK4 mRNA in keratinocyte- derived cell lines
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11023271/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Revealing the grammar of small RNA secretion using interpretable machine learning
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    ncbi.nlm.nih.gov/pmc/articles/PMC11019361/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The dimeric deubiquitinase USP28 integrates 53BP1 and MYC functions to limit DNA damage
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11024517/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Membrane to cortex attachment determines different mechanical phenotypes in LGR5+ and LGR5- colorectal cancer cells
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11026456/
  25. aacrjournals.org aacrjournals.org
    PRMT1 inhibition activates the interferon pathway to potentiate antitumor immunity and enhance checkpoint blockade efficacy in melanoma
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    aacrjournals.org/cancerres/article/84/3/419/733846/PRMT1-Inhibition-Activates-the-Interferon-Pathway
  26. www.sciencedirect.com www.sciencedirect.com
    Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
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    sciencedirect.com/science/article/pii/S221112472400439X
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Satellite double-stranded RNA induces mesenchymal transition in pancreatic cancer by regulating alternative splicing
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10943486/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HOXA5-induced lncRNA DNM3OS promotes human embryo lung fibroblast fibrosis via recruiting EZH2 to epigenetically suppress TSC2 expression
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10944743/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling the role of m6A effectors in the regulation of pluripotent reprogramming
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    ncbi.nlm.nih.gov/pmc/articles/PMC10986062/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP5 promotes tumorigenesis by activating Hedgehog/Gli1 signaling pathway in osteosarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10998757/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Role of HIV-1-Encoded microRNAs in Viral Replication
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    ncbi.nlm.nih.gov/pmc/articles/PMC10971904/
  32. Mar 2024
  33. www.sciencedirect.com www.sciencedirect.com
    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
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    sciencedirect.com/science/article/pii/S1097276524001758
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The BHLHE40‒PPM1F‒AMPK pathway regulates energy metabolism and is associated with the aggressiveness of endometrial cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10904277/
  35. 52.53.155.43 52.53.155.43
    SHP-1 inhibition targets leukaemia stem cells to restore immunosurveillance and enhance chemosensitivity by metabolic reprogramming
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    52.53.155.43/a85d3b9f92fdbe08a8488af8660c90612671e554/s41556-024-01349-3-html.html
  36. www.sciencedirect.com www.sciencedirect.com
    The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression
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    sciencedirect.com/science/article/pii/S009286742400117X
  37. Feb 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intrahepatic homeobox protein MSX-1 is a novel host restriction factor of hepatitis B virus
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    ncbi.nlm.nih.gov/pmc/articles/PMC10878074/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 and oncolytic EV-D68-encoded proteases differentially regulate pyroptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10878271/
  40. www.biorxiv.org www.biorxiv.org
    BET Degraders Reveal BRD4 Disruption of 7SK and P-TEFb is Critical for Effective Reactivation of Latent HIV in CD4+ T-cells
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    biorxiv.org/content/10.1101/2024.02.23.581756v1
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DUX4-r exerts a neomorphic activity that depends on GTF2I in acute lymphoblastic leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC10881058/
  42. breast-cancer-research.biomedcentral.com breast-cancer-research.biomedcentral.com
    Small molecule inhibitor targeting the Hsp70-Bim protein–protein interaction in estrogen receptor-positive breast cancer overcomes tamoxifen resistance
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    breast-cancer-research.biomedcentral.com/articles/10.1186/s13058-024-01790-0
  43. 52.53.155.43 52.53.155.43
    419-html.html
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    52.53.155.43/9ee9b923ebb85a391d8ef40b8ed2af8f0d12ae03/419-html.html
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncoprotein SET-associated transcription factor ZBTB11 triggers lung cancer metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10867109/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRL4B E3 ligase recruited by PRPF19 inhibits SARS-CoV-2 infection by targeting ORF6 for ubiquitin-dependent degradation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10865787/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of microtubule nucleation in mouse bone marrow-derived mast cells by ARF GTPase-activating protein GIT2
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    ncbi.nlm.nih.gov/pmc/articles/PMC10870779/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GPX3 supports ovarian cancer tumor progression in vivo and promotes expression of GDF15
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    ncbi.nlm.nih.gov/pmc/articles/PMC10862694/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Triple-Negative Breast Cancer Intrinsic FTSJ1 Favors Tumor Progression and Attenuates CD8+ T Cell Infiltration
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    ncbi.nlm.nih.gov/pmc/articles/PMC10854779/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF-1R mediates crosstalk between nasopharyngeal carcinoma cells and osteoclasts and promotes tumor bone metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10860326/
  50. 52.53.155.43 52.53.155.43
    RNA-guided RNA silencing by an Asgard archaeal Argonaute
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    52.53.155.43/299a104299b2de46de3d5132e96f6dd2d1482298/2023.12.14.571608v2.full-html.html
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exploiting epigenetic targets to overcome taxane resistance in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10861560/
  52. www.sciencedirect.com www.sciencedirect.com
    Proline restores mitochondrial function and reverses aging hallmarks in senescent cells
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    sciencedirect.com/science/article/pii/S2211124724000664
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EIF4A3-mediated biogenesis of circSTX6 promotes bladder cancer metastasis and cisplatin resistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC10759346/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The oncogenic role and regulatory mechanism of PGK1 in human non-small cell lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10759362/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mcam inhibits macrophage-mediated development of mammary gland through non-canonical Wnt signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10761817/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmaceutical targeting of OTUB2 sensitizes tumors to cytotoxic T cells via degradation of PD-L1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10761827/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMAD4 inhibits glycolysis in ovarian cancer through PI3K/AKT/HK2 signaling pathway by activating ARHGAP10
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    ncbi.nlm.nih.gov/pmc/articles/PMC10849991/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMYD3 promotes endometrial cancer through epigenetic regulation of LIG4/XRCC4/XLF complex in non-homologous end joining repair
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    ncbi.nlm.nih.gov/pmc/articles/PMC10774296/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC10524254/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytoplasmic accumulation and plasma membrane association of anillin and Ect2 promote confined migration and invasion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10802709/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRMS1L confers anticancer activity in non-small cell lung cancer by transcriptionally inducing a redox imbalance in the GPX2-ROS pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10832508/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    c-Fos regulated by TMPO/ERK axis promotes 5-FU resistance via inducing NANOG transcription in colon cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10794174/
  63. Jan 2024
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PICH deficiency limits the progression of MYC-induced B-cell lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10803365/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caloric restriction leads to druggable LSD1-dependent cancer stem cells expansion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10821871/
  66. dx.doi.org dx.doi.org
    Kaposi's sarcoma herpesvirus exploits the DNA damage response to circularize its genome
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    dx.doi.org/10.1093/nar/gkad1224
  67. Dec 2023
  68. www.sciencedirect.com www.sciencedirect.com
    Loss of α-1,2-mannosidase MAN1C1 promotes tumorigenesis of intrahepatic cholangiocarcinoma through enhancing CD133-FIP200 interaction
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    sciencedirect.com/science/article/pii/S2211124723016005
  69. www.sciencedirect.com www.sciencedirect.com
    Proteomic characterization of the colorectal cancer response to chemoradiation and targeted therapies reveals potential therapeutic strategies
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    sciencedirect.com/science/article/pii/S2666379123005050
  70. link.springer.com link.springer.com
    CASC4/GOLM2 drives high grade serous carcinoma anoikis resistance through the recycling of EGFR
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    link.springer.com/article/10.1038/s41417-023-00703-1
  71. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Lactate produced by alveolar type II cells suppresses inflammatory alveolar macrophages in acute lung injury
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202301722R
  72. Oct 2023
  73. 52.53.155.43 52.53.155.43
    Targeting UBR5 inhibits postsurgical breast cancer lung metastases by inducing CDC73 and p53 mediated apoptosis
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    52.53.155.43/dfd537dd38159a379f0051e34a95d721924018c7/Intl Journal of Cancer - 2023 - Yu - Targeting UBR5 inhibits postsurgical breast cancer lung metastases by inducing CDC73-html.html
  74. www.nature.com www.nature.com
    Pentapeptide PYRAE triggers ER stress-mediated apoptosis of breast cancer cells in mice by targeting RHBDF1-BiP interaction
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    nature.com/articles/s41401-023-01163-x
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Promyelocytic leukemia protein regulates angiogenesis and epithelial–mesenchymal transition to limit metastasis in MDA‐MB‐231 breast cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10552902/
  76. Sep 2023
  77. www.sciencedirect.com www.sciencedirect.com
    TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal
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    sciencedirect.com/science/article/pii/S1934590923002461
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    microRNAs slow translating ribosomes to prevent protein misfolding in eukaryotes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10505912/
  79. www.biorxiv.org www.biorxiv.org
    A Meta-Atlas of the Developing Human Cortex Identifies Modules Driving Cell Subtype Specification
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    biorxiv.org/content/10.1101/2023.09.12.557406v1
  80. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Yin-html.html
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    52.53.155.43/3f4c3b7a8c80fd686d3f27ef9d97ee6662a4385e/British J Pharmacology - 2023 - Yin-html.html
  81. www.sciencedirect.com www.sciencedirect.com
    CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance
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    sciencedirect.com/science/article/pii/S2211124723011427
  82. link.springer.com link.springer.com
    The Endolysosomal Transporter DMT1 is Required for Morphine Regulation of Neuronal Ferritin Heavy Chain
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    link.springer.com/article/10.1007/s11481-023-10082-x
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Crizotinib has Preclinical Efficacy in Philadelphia-negative Myeloproliferative Neoplasms
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    ncbi.nlm.nih.gov/pmc/articles/PMC9992133/
  84. Aug 2023
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The circadian clock circuitry modulates leukemia initiating cell activity in T-cell acute lymphoblastic leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC10464343/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Porcine reproductive and respiratory syndrome virus upregulates SMPDL3B to promote viral replication by modulating lipid metabolism
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    ncbi.nlm.nih.gov/pmc/articles/PMC10424083/
  87. 52.53.155.43 52.53.155.43
    MOF-mediated acetylation of SIRT6 disrupts SIRT6-FOXA2 interaction and represses SIRT6 tumor-suppressive function by upregulating ZEB2 in NSCLC
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    52.53.155.43/bd09065dee8428d4c17fca329effba1c6cc59b0c/PIIS2211124723009506-html.html
  88. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    β-Catenin Drives Butyrophilin-like Molecule Loss and γδ T-cell Exclusion in Colon Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC10398359/
  89. Jul 2023
  90. 52.53.155.43 52.53.155.43
    rational-design-and-development-of-selective-brd7-bromodomain-inhibitors-and-their-activity-in-prostate-cancer-html.html
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    52.53.155.43/fbc444166f400a01dc32894063d12537e1e236f5/rational-design-and-development-of-selective-brd7-bromodomain-inhibitors-and-their-activity-in-prostate-cancer-html.html
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness
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    ncbi.nlm.nih.gov/pmc/articles/PMC10354099/
  92. Jun 2023
  93. www.nature.com www.nature.com
    The effect of inhibition of receptor tyrosine kinase AXL on DNA damage response in ovarian cancer
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    nature.com/articles/s42003-023-05045-0
  94. aacrjournals.org aacrjournals.org
    Targeted MDM2 degradation reveals a new vulnerability for p53 inactivated triple negative breast cancer
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    aacrjournals.org/cancerdiscovery/article/13/5/1210/726189/Targeted-MDM2-Degradation-Reveals-a-New
  95. www.sciencedirect.com www.sciencedirect.com
    Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition
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    YAP1 regulates chondrogenic differentiation of ATDC5 promoted by temporary TNF-α stimulation through AMPK signaling pathway
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