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    The RNA Demethylases ALKBH5 and FTO Regulate the Translation of ATF4 mRNA in Sorafenib-Treated Hepatocarcinoma Cells
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    1. scibot 29 Sep 2024
      8453

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    ncbi.nlm.nih.gov/pmc/articles/PMC11352178/
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    V1bR enhances glucose-stimulated insulin secretion by paracrine production of glucagon which activates GLP-1 receptor
    1
    1. scibot 29 Sep 2024
      8453

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    ncbi.nlm.nih.gov/pmc/articles/PMC11365140/
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    Dihydrotestosterone Enhances MICA-Mediated Immune Responses to Epstein–Barr Virus-Associated Gastric Carcinoma
    1
    1. scibot 29 Sep 2024
      8453

      DOI: 10.3390/cancers16183219

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    ncbi.nlm.nih.gov/pmc/articles/PMC11429822/
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    PIM1 kinase promotes EMT-associated osimertinib resistance via regulating GSK3β signaling pathway in EGFR-mutant non-small cell lung cancer
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    1. scibot 29 Sep 2024
      pLKO.1-puromycin

      DOI: 10.1038/s41419-024-07039-0

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    Identification of Cellular Isoschaftoside-Mediated Anti-Senescence Mechanism in RAC2 and LINC00294
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    1. scibot 25 Sep 2024
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      DOI: 10.3390/molecules29174182

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    AXL inhibition prevents RPA2/CHK1-mediated homologous recombination to increase PARP inhibitor sensitivity in hepatocellular carcinoma
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    1. scibot 25 Sep 2024
      pLKO.1-puro

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    Targeting NAT10 inhibits osteosarcoma progression via ATF4/ASNS-mediated asparagine biosynthesis
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    1. scibot 25 Sep 2024
      Addgene_8453

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    sciencedirect.com/science/article/pii/S2666379124004555
  9. Aug 2024
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    Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer
    1
    1. scibot 28 Aug 2024
      plasmid_8453

      DOI: 10.1021/acs.jmedchem.3c00671

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    ncbi.nlm.nih.gov/pmc/articles/PMC10641717/
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    Myostatin regulates energy homeostasis through autocrine- and paracrine-mediated microenvironment communication
    1
    1. scibot 26 Aug 2024
      pLKO.1-puro

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    ncbi.nlm.nih.gov/pmc/articles/PMC11324308/
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    Promoter Methylation Leads to Hepatocyte Nuclear Factor 4A Loss and Pancreatic Cancer Aggressiveness
    1
    1. scibot 26 Aug 2024
      8453

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    ncbi.nlm.nih.gov/pmc/articles/PMC11330932/
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    The deubiquitinase OTUD1 stabilizes NRF2 to alleviate hepatic ischemia/reperfusion injury
    1
    1. scibot 26 Aug 2024
      8453

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    Specific multivalent molecules boost CRISPR-mediated transcriptional activation
    1
    1. scibot 26 Aug 2024
      8453

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    ncbi.nlm.nih.gov/pmc/articles/PMC11341856/
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    Identification of a novel gene signature related to prognosis and metastasis in gastric cancer
    1
    1. scibot 26 Aug 2024
      plasmid_8453

      DOI: 10.1007/s13402-024-00932-y

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    EZH2 represses mesenchymal genes and upholds the epithelial state of breast carcinoma cells
    1
    1. scibot 26 Aug 2024
      Addgene_8453

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    Tumor-derived GLI1 promotes remodeling of the immune tumor microenvironment in melanoma
    1
    1. scibot 22 Aug 2024
      Addgene_8453

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    Centenarian hippocampus displays high levels of astrocytic metallothioneins
    1
    1. scibot 22 Aug 2024
      plasmid_8453

      DOI: 10.1111/acel.14201

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  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elimination of damaged mitochondria during UVB‐induced senescence is orchestrated by NIX‐dependent mitophagy
    1
    1. scibot 22 Aug 2024
      plasmid_8453

      DOI: 10.1111/acel.14186

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    Tight Junction Component Occludin Binds to FIP5 to Regulate Endosome Trafficking and Mitotic Spindle Function
    1
    1. scibot 22 Aug 2024
      Addgene_8453

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    Dopaminylation of endothelial TPI1 suppresses ferroptotic angiocrine signals to promote lung regeneration over fibrosis
    1
    1. scibot 19 Aug 2024
      Plasmid_8453

      DOI: 10.1016/j.cmet.2024.07.008

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  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TERT upstream promoter methylation regulates TERT expression and acts as a therapeutic target in TERT promoter mutation-negative thyroid cancer
    1
    1. scibot 18 Aug 2024
      8453

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    Blocking methionine catabolism induces senescence and confers vulnerability to GSK3 inhibition in liver cancer
    1
    1. scibot 18 Aug 2024
      Addgene_8453

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    SARS-CoV-2 nucleocapsid protein promotes self-deacetylation by inducing HDAC6 to facilitate viral replication
    1
    1. scibot 17 Aug 2024
      8453

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    Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation
    1
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      8453

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  26. Jul 2024
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    MUC1-C Dependence for the Progression of Pancreatic Neuroendocrine Tumors Identifies a Druggable Target for the Treatment of This Rare Cancer
    1
    1. scibot 31 Jul 2024
      Plasmid_8453

      DOI: 10.3390/biomedicines12071509

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  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LSM12-EPAC1 defines a neuroprotective pathway that sustains the nucleocytoplasmic RAN gradient
    1
    1. scibot 22 Jul 2024
      plasmid_8453

      DOI: 10.1371/journal.pbio.3001002

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  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling
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      RRID:Addgene_8453

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  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA-guided RNA silencing by an Asgard archaeal Argonaute
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      RRID:Addgene_8453

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  31. Jun 2024
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Improvement of histone deacetylase inhibitor efficacy by SN38 through TWIST1 suppression in synovial sarcoma
    1
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      8453

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    Lovastatin-Induced Mitochondrial Oxidative Stress Leads to the Release of mtDNA to Promote Apoptosis by Activating cGAS-STING Pathway in Human Colorectal Cancer Cells
    1
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      plasmid_8453

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  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRMT5-mediated methylation of STAT3 is required for lung cancer stem cell maintenance and tumour growth
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      plasmid_8453

      DOI: 10.1038/s42003-024-06290-7

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  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The balance between antiviral and antibacterial responses during M. tuberculosis infection is regulated by the ubiquitin ligase CBL
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    1. scibot 21 Jun 2024
      Plasmid_8453

      DOI: 10.1101/2024.05.15.594178

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  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caspase-4 promotes metastasis and interferon-γ-induced pyroptosis in lung adenocarcinoma
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    Lysine acetyltransferase 14 mediates TGF-β-induced fibrosis in ovarian endometrioma via co-operation with serum response factor
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      RRID:Addgene_8453

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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LncRNA IRAIN overcomes imatinib resistance in chronic myeloid leukemia via NF-κB/CD44 pathway inhibition
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      8453

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  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulation of Paracellular Permeability in SARS-CoV-2 Blood-to-Brain Transcytosis
    1
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      8453

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  40. www.biorxiv.org www.biorxiv.org
    The tumor-maintaining function of UTX/KDM6A in DNA replication and the PARP1-dependent repair pathway
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      RRID:Addgene_8453

      DOI: 10.1101/2024.05.31.596824

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    biorxiv.org/content/10.1101/2024.05.31.596824v1
  41. www.sciencedirect.com www.sciencedirect.com
    Cancer-specific epigenome identifies oncogenic hijacking by nuclear factor I family proteins for medulloblastoma progression
    3
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    sciencedirect.com/science/article/pii/S1534580724003307
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microbiota enterotoxigenic Bacteroides fragilis-secreted BFT-1 promotes breast cancer cell stemness and chemoresistance through its functional receptor NOD1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11131025/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic movement of the Golgi unit and its glycosylation enzyme zones
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      plasmid_8453

      DOI: 10.1038/s41467-024-48901-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11130159/
  44. May 2024
  45. www.biorxiv.org www.biorxiv.org
    Spatiotemporal proteomics reveals the biosynthetic lysosomal membrane protein interactome in neurons
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      plasmid_8453

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    biorxiv.org/content/10.1101/2024.05.16.594502v1
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    Deficiency of UCHL1 results in insufficient decidualization accompanied by impaired dNK modulation and eventually miscarriage
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  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    METTL8 links mt-tRNA m3C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity
    1
    1. scibot 19 May 2024
      8453

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  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxia-induced NOS1 as a therapeutic target in hypercholesterolemia-related colorectal cancer
    1
    1. scibot 19 May 2024
      8453

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  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mecp2 fine-tunes quiescence exit by targeting nuclear receptors
    1
    1. scibot 17 May 2024
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      DOI: 10.7554/eLife.89912

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  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CYB561 supports the neuroendocrine phenotype in castration-resistant prostate cancer
    1
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  51. www.sciencedirect.com www.sciencedirect.com
    USP7 promotes IgA class switching through stabilizing RUNX3 for germline transcription activation
    1
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      Addgene8453

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  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DDX18 Facilitates the Tumorigenesis of Lung Adenocarcinoma by Promoting Cell Cycle Progression through the Upregulation of CDK4
    1
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      Plasmid_8453

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  53. 52.53.155.43 52.53.155.43
    TERC promotes non-small cell lung cancer progression by facilitating the nuclear localization of TERT
    1
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      RRID: Addgene_8453

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  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of proteoglycan synthesis genes in osteosarcoma stem cells
    1
    1. scibot 05 May 2024
      8453

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  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRRX1-TOP2A interaction is a malignancy-promoting factor in human malignant peripheral nerve sheath tumours
    1
    1. scibot 05 May 2024
      8453

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  56. Apr 2024
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined SNPs sequencing and allele specific proteomics capture reveal functional causality underpinning the 2p25 prostate cancer susceptibility locus
    1
    1. scibot 30 Apr 2024
      8453

      DOI: 10.21203/rs.3.rs-3943095/v1

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  58. www.pnas.org www.pnas.org
    NOVA1 acts as an oncogenic RNA-binding protein to regulate cholesterol homeostasis in human glioblastoma cells
    1
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      Addgene_8453

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  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation by the RNA-binding protein Unkempt at its effector interface
    1
    1. scibot 23 Apr 2024
      8453

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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An EBV-related CD4 TCR immunotherapy inhibits tumor growth in an HLA-DP5+ nasopharyngeal cancer mouse model
    1
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      8453

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  61. www.embopress.org www.embopress.org
    PRODH safeguards human naive pluripotency by limiting mitochondrial oxidative phosphorylation and reactive oxygen species production
    1
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      8453

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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lysophosphatidic acid down-regulates human RIPK4 mRNA in keratinocyte- derived cell lines
    1
    1. scibot 23 Apr 2024
      pLKO.puro

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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Revealing the grammar of small RNA secretion using interpretable machine learning
    1
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      8453

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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The dimeric deubiquitinase USP28 integrates 53BP1 and MYC functions to limit DNA damage
    1
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      plasmid_8453

      DOI: 10.1093/nar/gkae004

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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Membrane to cortex attachment determines different mechanical phenotypes in LGR5+ and LGR5- colorectal cancer cells
    1
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      plasmid_8453

      DOI: 10.1038/s41467-024-47227-2

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  66. aacrjournals.org aacrjournals.org
    PRMT1 inhibition activates the interferon pathway to potentiate antitumor immunity and enhance checkpoint blockade efficacy in melanoma
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      DOI: 10.1158/0008-5472.CAN-23-1082

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    aacrjournals.org/cancerres/article/84/3/419/733846/PRMT1-Inhibition-Activates-the-Interferon-Pathway
  67. www.sciencedirect.com www.sciencedirect.com
    Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Satellite double-stranded RNA induces mesenchymal transition in pancreatic cancer by regulating alternative splicing
    1
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      pLKO.1-Puromycin

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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HOXA5-induced lncRNA DNM3OS promotes human embryo lung fibroblast fibrosis via recruiting EZH2 to epigenetically suppress TSC2 expression
    1
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      pLKO.1-puro

      DOI: 10.21037/jtd-23-1145

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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling the role of m6A effectors in the regulation of pluripotent reprogramming
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      plasmid_8453

      DOI: 10.1186/s40246-024-00597-6

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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP5 promotes tumorigenesis by activating Hedgehog/Gli1 signaling pathway in osteosarcoma
    1
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      pLKO.1 puro vector

      DOI: 10.62347/JMFF8182

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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Role of HIV-1-Encoded microRNAs in Viral Replication
    1
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      plasmid_8453

      DOI: 10.3390/microorganisms12030425

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  73. Mar 2024
  74. www.sciencedirect.com www.sciencedirect.com
    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
    1
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      Plasmid_8453

      DOI: 10.1016/j.molcel.2024.02.032

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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The BHLHE40‒PPM1F‒AMPK pathway regulates energy metabolism and is associated with the aggressiveness of endometrial cancer
    1
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      pLKO.1-puro

      DOI: 10.1016/j.jbc.2024.105695

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  76. 52.53.155.43 52.53.155.43
    SHP-1 inhibition targets leukaemia stem cells to restore immunosurveillance and enhance chemosensitivity by metabolic reprogramming
    1
    1. scibot 15 Mar 2024
      8453, Addgene

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  77. www.sciencedirect.com www.sciencedirect.com
    The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression
    1
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      Addgene8453

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  78. Feb 2024
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intrahepatic homeobox protein MSX-1 is a novel host restriction factor of hepatitis B virus
    1
    1. scibot 29 Feb 2024
      pLKO.1

      DOI: 10.1128/jvi.01345-23

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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 and oncolytic EV-D68-encoded proteases differentially regulate pyroptosis
    1
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      pLKO.1-puro

      DOI: 10.1128/jvi.01909-23

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  81. www.biorxiv.org www.biorxiv.org
    BET Degraders Reveal BRD4 Disruption of 7SK and P-TEFb is Critical for Effective Reactivation of Latent HIV in CD4+ T-cells
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      plasmid_8453

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  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DUX4-r exerts a neomorphic activity that depends on GTF2I in acute lymphoblastic leukemia
    1
    1. scibot 28 Feb 2024
      RRID:Addgene_8453

      DOI: 10.1126/sciadv.adi3771

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  83. breast-cancer-research.biomedcentral.com breast-cancer-research.biomedcentral.com
    Small molecule inhibitor targeting the Hsp70-Bim protein–protein interaction in estrogen receptor-positive breast cancer overcomes tamoxifen resistance
    1
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  84. 52.53.155.43 52.53.155.43
    419-html.html
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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncoprotein SET-associated transcription factor ZBTB11 triggers lung cancer metastasis
    1
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      8453

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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRL4B E3 ligase recruited by PRPF19 inhibits SARS-CoV-2 infection by targeting ORF6 for ubiquitin-dependent degradation
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    1. scibot 21 Feb 2024
      8453

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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of microtubule nucleation in mouse bone marrow-derived mast cells by ARF GTPase-activating protein GIT2
    1
    1. scibot 21 Feb 2024
      pLKO.1 puro

      DOI: 10.3389/fimmu.2024.1321321

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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GPX3 supports ovarian cancer tumor progression in vivo and promotes expression of GDF15
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      plasmid_8453

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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Triple-Negative Breast Cancer Intrinsic FTSJ1 Favors Tumor Progression and Attenuates CD8+ T Cell Infiltration
    1
    1. scibot 15 Feb 2024
      PLKO

      DOI: 10.3390/cancers16030597

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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF-1R mediates crosstalk between nasopharyngeal carcinoma cells and osteoclasts and promotes tumor bone metastasis
    1
    1. scibot 15 Feb 2024
      pLKO.1-puro

      DOI: 10.1186/s13046-024-02970-8

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  91. 52.53.155.43 52.53.155.43
    RNA-guided RNA silencing by an Asgard archaeal Argonaute
    1
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exploiting epigenetic targets to overcome taxane resistance in prostate cancer
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  93. www.sciencedirect.com www.sciencedirect.com
    Proline restores mitochondrial function and reverses aging hallmarks in senescent cells
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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EIF4A3-mediated biogenesis of circSTX6 promotes bladder cancer metastasis and cisplatin resistance
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  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The oncogenic role and regulatory mechanism of PGK1 in human non-small cell lung cancer
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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mcam inhibits macrophage-mediated development of mammary gland through non-canonical Wnt signaling
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  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmaceutical targeting of OTUB2 sensitizes tumors to cytotoxic T cells via degradation of PD-L1
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  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMAD4 inhibits glycolysis in ovarian cancer through PI3K/AKT/HK2 signaling pathway by activating ARHGAP10
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMYD3 promotes endometrial cancer through epigenetic regulation of LIG4/XRCC4/XLF complex in non-homologous end joining repair
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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytoplasmic accumulation and plasma membrane association of anillin and Ect2 promote confined migration and invasion
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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRMS1L confers anticancer activity in non-small cell lung cancer by transcriptionally inducing a redox imbalance in the GPX2-ROS pathway
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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    c-Fos regulated by TMPO/ERK axis promotes 5-FU resistance via inducing NANOG transcription in colon cancer
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  104. Jan 2024
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PICH deficiency limits the progression of MYC-induced B-cell lymphoma
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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caloric restriction leads to druggable LSD1-dependent cancer stem cells expansion
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  107. dx.doi.org dx.doi.org
    Kaposi's sarcoma herpesvirus exploits the DNA damage response to circularize its genome
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  108. Dec 2023
  109. www.sciencedirect.com www.sciencedirect.com
    Loss of α-1,2-mannosidase MAN1C1 promotes tumorigenesis of intrahepatic cholangiocarcinoma through enhancing CD133-FIP200 interaction
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  110. www.sciencedirect.com www.sciencedirect.com
    Proteomic characterization of the colorectal cancer response to chemoradiation and targeted therapies reveals potential therapeutic strategies
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  111. link.springer.com link.springer.com
    CASC4/GOLM2 drives high grade serous carcinoma anoikis resistance through the recycling of EGFR
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  112. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Lactate produced by alveolar type II cells suppresses inflammatory alveolar macrophages in acute lung injury
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  113. Oct 2023
  114. 52.53.155.43 52.53.155.43
    Targeting UBR5 inhibits postsurgical breast cancer lung metastases by inducing CDC73 and p53 mediated apoptosis
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    52.53.155.43/dfd537dd38159a379f0051e34a95d721924018c7/Intl Journal of Cancer - 2023 - Yu - Targeting UBR5 inhibits postsurgical breast cancer lung metastases by inducing CDC73-html.html
  115. www.nature.com www.nature.com
    Pentapeptide PYRAE triggers ER stress-mediated apoptosis of breast cancer cells in mice by targeting RHBDF1-BiP interaction
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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Promyelocytic leukemia protein regulates angiogenesis and epithelial–mesenchymal transition to limit metastasis in MDA‐MB‐231 breast cancer cells
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  117. Sep 2023
  118. www.sciencedirect.com www.sciencedirect.com
    TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    microRNAs slow translating ribosomes to prevent protein misfolding in eukaryotes
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  120. www.biorxiv.org www.biorxiv.org
    A Meta-Atlas of the Developing Human Cortex Identifies Modules Driving Cell Subtype Specification
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  121. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Yin-html.html
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  122. www.sciencedirect.com www.sciencedirect.com
    CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance
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  123. link.springer.com link.springer.com
    The Endolysosomal Transporter DMT1 is Required for Morphine Regulation of Neuronal Ferritin Heavy Chain
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  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Crizotinib has Preclinical Efficacy in Philadelphia-negative Myeloproliferative Neoplasms
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  125. Aug 2023
  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The circadian clock circuitry modulates leukemia initiating cell activity in T-cell acute lymphoblastic leukemia
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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Porcine reproductive and respiratory syndrome virus upregulates SMPDL3B to promote viral replication by modulating lipid metabolism
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  128. 52.53.155.43 52.53.155.43
    MOF-mediated acetylation of SIRT6 disrupts SIRT6-FOXA2 interaction and represses SIRT6 tumor-suppressive function by upregulating ZEB2 in NSCLC
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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-Catenin Drives Butyrophilin-like Molecule Loss and γδ T-cell Exclusion in Colon Cancer
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  130. Jul 2023
  131. 52.53.155.43 52.53.155.43
    rational-design-and-development-of-selective-brd7-bromodomain-inhibitors-and-their-activity-in-prostate-cancer-html.html
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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness
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  133. Jun 2023
  134. www.nature.com www.nature.com
    The effect of inhibition of receptor tyrosine kinase AXL on DNA damage response in ovarian cancer
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  135. aacrjournals.org aacrjournals.org
    Targeted MDM2 degradation reveals a new vulnerability for p53 inactivated triple negative breast cancer
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  136. www.sciencedirect.com www.sciencedirect.com
    Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition
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  137. aacrjournals.org aacrjournals.org
    Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer
    1
    1. scibot 03 Jun 2023
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      DOI: 10.1158/0008-5472.CAN-22-2045

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  138. www.sciencedirect.com www.sciencedirect.com
    KLHL7 promotes hepatocellular carcinoma progression and molecular therapy resistance by degrading RASA2
    1
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    sciencedirect.com/science/article/pii/S2589004223009914
  139. May 2023
  140. www.sciencedirect.com www.sciencedirect.com
    Modeling human ectopic pregnancies with trophoblast and vascular organoids
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    sciencedirect.com/science/article/pii/S2211124723005570
  141. Apr 2023
  142. www.nature.com www.nature.com
    Glucocerebrosidase is imported into mitochondria and preserves complex I integrity and energy metabolism
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      DOI: 10.1038/s41467-023-37454-4

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    nature.com/articles/s41467-023-37454-4
  143. www.sciencedirect.com www.sciencedirect.com
    PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection
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  144. Mar 2023
  145. academic.oup.com academic.oup.com
    Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers
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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad172/7079642
  146. 52.53.155.43 52.53.155.43
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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined Inhibition of Smoothened and the DNA Damage Checkpoint WEE1 Exerts Antitumor Activity in Cholangiocarcinoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9978885/
  148. Feb 2023
  149. cancerci.biomedcentral.com cancerci.biomedcentral.com
    Krüppel-like factor 9 (KLF9) links hormone dysregulation and circadian disruption to breast cancer pathogenesis
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    cancerci.biomedcentral.com/articles/10.1186/s12935-023-02874-1
  150. www.sciencedirect.com www.sciencedirect.com
    The mitochondrial chaperone TRAP-1 regulates the glutamine metabolism in tumor cells
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    sciencedirect.com/science/article/abs/pii/S156772492300020X
  151. www.sciencedirect.com www.sciencedirect.com
    Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation
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  152. Jan 2023
  153. www.sciencedirect.com www.sciencedirect.com
    Decoding m6A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance
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      RRID:Addgene_8453

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    sciencedirect.com/science/article/pii/S1934590922004878
  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SAYSD1 senses UFMylated ribosome to safeguard co-translational protein translocation at the endoplasmic reticulum
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    ncbi.nlm.nih.gov/pmc/articles/PMC10010011/
  155. www.sciencedirect.com www.sciencedirect.com
    TRIM28 secures skeletal stem cell fate during skeletogenesis by silencing neural gene expression and repressing GREM1/AKT/mTOR signaling axis
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    sciencedirect.com/science/article/pii/S2211124723000232
  156. aacrjournals.org aacrjournals.org
    Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells
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    aacrjournals.org/mcr/article/20/12/1785/710999/Loss-of-VOPP1-Contributes-to-BET-Inhibitor
  157. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of interaction between ROCK1 and Rubicon restores autophagy in endothelial cells and attenuates brain injury after prolonged ischemia
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15721
  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance
    1
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  159. www.sciencedirect.com www.sciencedirect.com
    METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
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    sciencedirect.com/science/article/pii/S1934590922004908
  160. Nov 2022
  161. www.sciencedirect.com www.sciencedirect.com
    Hypoxia activated HGF expression in pancreatic stellate cells confers resistance of pancreatic cancer cells to EGFR inhibition
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  162. www.sciencedirect.com www.sciencedirect.com
    Bortezomib inhibits ZIKV/DENV by interfering with viral polyprotein cleavage via the ERAD pathway
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    sciencedirect.com/science/article/pii/S2451945622003579
  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nucleoplasmic lamin C rapidly accumulates at sites of nuclear envelope rupture with BAF and cGAS
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  164. Oct 2022
  165. aacrjournals.org aacrjournals.org
    CircIPO7 Promotes Nasopharyngeal Carcinoma Metastasis and Cisplatin Chemoresistance by Facilitating YBX1 Nuclear Localization
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    aacrjournals.org/clincancerres/article/28/20/4521/709577/CircIPO7-Promotes-Nasopharyngeal-Carcinoma
  166. Sep 2022
  167. journals.biologists.com journals.biologists.com
    TGFBR3 supports anoikis through suppressing ATF4 signaling
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  168. www.sciencedirect.com www.sciencedirect.com
    Meteorin links the bone marrow hypoxic state to hematopoietic stem/progenitor cell mobilization
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    sciencedirect.com/science/article/pii/S2211124722011937
  169. www.sciencedirect.com www.sciencedirect.com
    TRIM56 impairs HBV infection and replication by inhibiting HBV core promoter activity
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    sciencedirect.com/science/article/pii/S0166354222001759
  170. Aug 2022
  171. aacrjournals.org aacrjournals.org
    Proteomic mapping and targeting of mitotic pericentriolar material in tumors bearing centrosome amplification
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    aacrjournals.org/cancerres/article/82/14/2576/706950/Proteomic-Mapping-and-Targeting-of-Mitotic
  172. Jul 2022
  173. www.sciencedirect.com www.sciencedirect.com
    HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs
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  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacotherapy alleviates pathological changes in human direct reprogrammed neuronal cell model of myotonic dystrophy type 1
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  175. www.sciencedirect.com www.sciencedirect.com
    EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks
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  176. Jun 2022
  177. www.sciencedirect.com www.sciencedirect.com
    A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of its bound metabolic mRNAs
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  178. May 2022
  179. www.researchsquare.com www.researchsquare.com
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  180. www.sciencedirect.com www.sciencedirect.com
    Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during angiogenesis
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  181. aacrjournals.org aacrjournals.org
    Concurrent Inhibition of ERK and Farnesyltransferase Suppresses the Growth of HRAS Mutant Head and Neck Squamous Cell Carcinoma
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  182. Apr 2022
  183. www.sciencedirect.com www.sciencedirect.com
    Functional genetic screen identifies ITPR3/calcium/RELB axis as a driver of colorectal cancer metastatic liver colonization
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  184. www.sciencedirect.com www.sciencedirect.com
    Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MLL5 is involved in retinal photoreceptor maturation through facilitating CRX-mediated photoreceptor gene transactivation
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  186. Mar 2022
  187. www.sciencedirect.com www.sciencedirect.com
    Positive feedback regulation of microglial glucose metabolism by histone H4 lysine 12 lactylation in Alzheimer’s disease
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  188. Jan 2022
  189. journals.plos.org journals.plos.org
    Occludin is a target of Src kinase and promotes lipid secretion by binding to BTN1a1 and XOR
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biphasic regulation of glutamine consumption by WNT during osteoblast differentiation
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  191. link.springer.com link.springer.com
    Restriction of extracellular lipids renders pancreatic cancer dependent on autophagy
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  192. Dec 2021
  193. www.mdpi.com www.mdpi.com
    Characterization of Type 1 Angiotensin II Receptor Activation Induced Dual-Specificity MAPK Phosphatase Gene Expression Changes in Rat Vascular Smooth Muscle Cells
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  194. www.sciencedirect.com www.sciencedirect.com
    A mechanistic basis for the malignant progression of salivary gland tumors
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      Addgene_8453

      DOI: 10.1016/j.isci.2021.103508

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    sciencedirect.com/science/article/pii/S2589004221014796
  195. Nov 2021
  196. www.sciencedirect.com www.sciencedirect.com
    TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment
    1
    1. scibot 17 Nov 2021
      RRID:Addgene_8453

      DOI: 10.1016/j.celrep.2021.110018

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    sciencedirect.com/science/article/pii/S221112472101500X
  197. www.sciencedirect.com www.sciencedirect.com
    Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring
    2
    1. scibot 17 Nov 2021
      RRID:AB_8453

      DOI: 10.1016/j.celrep.2021.109912

      Resource: RRID:Addgene_8453

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_8453

      Curator comments: pLKO.1 puro

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      RRID:Addgene_8453 RRIDCUR:Unresolved RRIDCUR:Incorrect
    2. scibot 03 Nov 2021
      plasmid_8453

      DOI: 10.1016/j.celrep.2021.109912

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      RRID:Addgene_8453
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    sciencedirect.com/science/article/pii/S2211124721013851
  198. Oct 2021
  199. www.sciencedirect.com www.sciencedirect.com
    Differential m6A RNA landscapes across hematopoiesis reveal a role for IGF2BP2 in preserving hematopoietic stem cell function
    1
    1. scibot 22 Oct 2021
      Addgene_8453

      DOI: 10.1016/j.stem.2021.09.014

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      RRID:Addgene_8453
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    sciencedirect.com/science/article/pii/S1934590921003908
  200. www.sciencedirect.com www.sciencedirect.com
    Tyrosine Phosphorylation of DEPTOR Functions as a Molecular Switch to Activate mTOR Signaling
    1
    1. scibot 14 Oct 2021
      RRID:Addgene_8453

      DOI: 10.1016/j.jbc.2021.101291

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    sciencedirect.com/science/article/pii/S0021925821010966
  201. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Functional differences between Hsp105/110 family proteins in cell proliferation, cell division, and drug sensitivity
    1
    1. scibot 08 Oct 2021
      plasmid_8453

      DOI: 10.1002/jcb.30158

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    onlinelibrary.wiley.com/doi/10.1002/jcb.30158
  202. Sep 2021
  203. www.sciencedirect.com www.sciencedirect.com
    The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy
    1
    1. scibot 11 Sep 2021
      Cat# 8453

      DOI: 10.1016/j.cmet.2021.08.012

      Resource: RRID:Addgene_8453

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      RRIDCUR:Missing RRID:Addgene_8453
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    sciencedirect.com/science/article/pii/S1550413121003752
  204. www.sciencedirect.com www.sciencedirect.com
    Cilium induction triggers differentiation of glioma stem cells
    1
    1. scibot 08 Sep 2021
      RRID:Addgene_8453

      DOI: 10.1016/j.celrep.2021.109656

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    sciencedirect.com/science/article/pii/S2211124721010998
  205. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
    2
    1. scibot 04 Sep 2021
      Addgene_8453

      DOI: 10.7554/eLife.65872

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      RRID:Addgene_8453
    2. scibot 04 Sep 2021
      RRID:Addgene_84530

      DOI: 10.7554/eLife.65872

      Resource: RRID:Addgene_8453

      Curator: @evieth

      SciCrunch record: RRID:Addgene_8453

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      RRIDCUR:Incorrect RRID:Addgene_8453 RRIDCUR:Unresolved
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    ncbi.nlm.nih.gov/pmc/articles/PMC8387021/
  206. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The cAMP effector PKA mediates Moody GPCR signaling in Drosophila blood–brain barrier formation and maturation
    1
    1. scibot 04 Sep 2021
      RRID:AB_2568479RRID:AB_2568479

      DOI: 10.7554/eLife.68275

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      Curator: @evieth

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      RRID:Addgene_8453 RRIDCUR:Unresolved
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    ncbi.nlm.nih.gov/pmc/articles/PMC8390003/
  207. Aug 2021
  208. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRD9 is a critical regulator of androgen receptor signaling and prostate cancer progression
    1
    1. scibot 17 Aug 2021
      RRID:Addgene_8453

      DOI: 10.1158/0008-5472.CAN-20-1417

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    ncbi.nlm.nih.gov/pmc/articles/PMC8026650/
  209. www.sciencedirect.com www.sciencedirect.com
    PHB Associates with the HIRA Complex to Control an Epigenetic-Metabolic Circuit in Human ESCs
    1
    1. scibot 09 Aug 2021
      plasmid_8453

      DOI: 10.1016/j.stem.2016.11.002

      Resource: RRID:Addgene_8453

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      RRID:Addgene_8453
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    sciencedirect.com/science/article/pii/S1934590916303988
  210. www.jneurosci.org www.jneurosci.org
    GPR120 signaling controls amyloid-β degrading activity of matrix metalloproteinases
    1
    1. scibot 07 Aug 2021
      RRID:Addgene_8453

      DOI: 10.1523/JNEUROSCI.2595-20.2021

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      RRID:Addgene_8453
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    jneurosci.org/content/41/28/6173
  211. www.sciencedirect.com www.sciencedirect.com
    Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance
    1
    1. scibot 06 Aug 2021
      plasmid_8453

      DOI: 10.1016/j.ccell.2017.10.008

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    sciencedirect.com/science/article/pii/S1535610817304610
  212. www.sciencedirect.com www.sciencedirect.com
    METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation
    1
    1. scibot 05 Aug 2021
      Cat# 8453

      DOI: 10.1016/j.molcel.2021.06.031

      Resource: RRID:Addgene_8453

      Curator: @Naa003

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      RRID:Addgene_8453 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1097276521005426
  213. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    14–3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling
    1
    1. scibot 05 Aug 2021
      plasmid_8453

      DOI: 10.1186/s13046-018-1007-9

      Resource: RRID:Addgene_8453

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      RRID:Addgene_8453
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    ncbi.nlm.nih.gov/pmc/articles/PMC6319010/
  214. Jul 2021
  215. www.sciencedirect.com www.sciencedirect.com
    DEAD-Box Helicase 18 Counteracts PRC2 to Safeguard Ribosomal DNA in Pluripotency Regulation
    1
    1. scibot 30 Jul 2021
      Addgene, # 8453

      DOI: 10.1016/j.celrep.2019.12.021

      Resource: RRID:Addgene_8453

      Curator: @ethanbadger

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      RRID:Addgene_8453 RRIDCUR:Unrecognized
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    sciencedirect.com/science/article/pii/S2211124719316717
  216. www.sciencedirect.com www.sciencedirect.com
    Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity
    1
    1. scibot 29 Jul 2021
      RRID:Addgene_8453

      DOI: 10.1016/j.celrep.2019.07.070

      Resource: RRID:Addgene_8453

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S221112471930974X
  217. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Depletion of the Transcriptional Coactivator Amplified in Breast Cancer 1 (AIB1) Uncovers Functionally Distinct Subpopulations in Triple-Negative Breast Cancer
    1
    1. scibot 29 Jul 2021
      #8453; Addgene

      DOI: 10.1016/j.neo.2019.07.001

      Resource: RRID:Addgene_8453

      Curator: @bandrow

      SciCrunch record: RRID:Addgene_8453

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      RRIDCUR:Unrecognized RRID:Addgene_8453
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    ncbi.nlm.nih.gov/pmc/articles/PMC6706655/
  218. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 29 Jul 2021
      plasmid_8453

      DOI: 10.1038/s41421-018-0068-4

      Resource: RRID:Addgene_8453

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      RRID:Addgene_8453
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    ncbi.nlm.nih.gov/pmc/articles/PMC6312541/
  219. www.sciencedirect.com www.sciencedirect.com
    IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation
    1
    1. scibot 28 Jul 2021
      Plasmid: pLKO.1 puro

      DOI: 10.1016/j.chom.2019.05.002

      Resource: RRID:Addgene_8453

      Curator: @ethanbadger

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      RRID:Addgene_8453 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1931312819302471
  220. www.cell.com www.cell.com
    Untitled document
    1
    1. scibot 28 Jul 2021
      plasmid_8453

      DOI: 10.1016/j.ccell.2017.10.008

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    cell.com/cancer-cell/abstract/S1535-6108(17)30461-0
  221. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 27 Jul 2021
      Plasmid_8453

      DOI: 10.1016/j.immuni.2018.10.011

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      RRID:Addgene_8453
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    sciencedirect.com/science/article/pii/S107476131830476X
  222. www.sciencedirect.com www.sciencedirect.com
    Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity
    1
    1. scibot 22 Jul 2021
      RRID:Addgene_8453

      DOI: 10.1016/j.ccell.2021.06.016

      Resource: RRID:Addgene_8453

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      RRID:Addgene_8453
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    sciencedirect.com/science/article/pii/S153561082100338X
  223. www.sciencedirect.com www.sciencedirect.com
    SIRT4 is an early regulator of branched-chain amino acid catabolism that promotes adipogenesis
    1
    1. scibot 14 Jul 2021
      Plasmid_8453

      DOI: 10.1016/j.celrep.2021.109345

      Resource: RRID:Addgene_8453

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      RRID:Addgene_8453
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    sciencedirect.com/science/article/pii/S221112472100721X
  224. Jun 2021
  225. www.sciencedirect.com www.sciencedirect.com
    Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome
    1
    1. scibot 30 Jun 2021
      Addgene #8453

      DOI: 10.1016/j.celrep.2021.109321

      Resource: RRID:Addgene_8453

      Curator: @Naa003

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      RRIDCUR:Missing RRID:Addgene_8453
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    sciencedirect.com/science/article/pii/S2211124721006975
  226. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Surface AMP deaminase 2 as a novel regulator modifying extracellular adenine nucleotide metabolism
    1
    1. scibot 26 Jun 2021
      RRID:Addgene_8453

      DOI: 10.1096/fj.202002658RR

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202002658RR
  227. www.sciencedirect.com www.sciencedirect.com
    Evaluation of glycolytic rates in human hematopoietic stem/progenitor cells after target gene depletion
    1
    1. scibot 15 Jun 2021
      plasmid_8453

      DOI: 10.1016/j.xpro.2021.100603

      Resource: RRID:Addgene_8453

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    sciencedirect.com/science/article/pii/S2666166721003105
  228. May 2021
  229. link.springer.com link.springer.com
    miR-637 Prevents Glioblastoma Progression by Interrupting ZEB2/WNT/β-catenin Cascades
    1
    1. scibot 29 May 2021
      RRID:Addgene_8453

      DOI: 10.1007/s10571-021-01107-1

      Resource: RRID:Addgene_8453

      Curator: @scibot

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      RRID:Addgene_8453
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    link.springer.com/article/10.1007/s10571-021-01107-1