1,215 Matching Annotations
  1. Nov 2023
  2. www.sciencedirect.com www.sciencedirect.com
    Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication
    1
    1. scibot 19 Nov 2023
      CVCL_0030

      DOI: 10.1016/j.molcel.2021.03.003

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    sciencedirect.com/science/article/pii/S1097276521001714
  3. www.sciencedirect.com www.sciencedirect.com
    Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy
    1
    1. scibot 17 Nov 2023
      RRID:CVCL_0030

      DOI: 10.1016/j.chembiol.2023.10.010

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    sciencedirect.com/science/article/pii/S2451945623003719
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery and biological evaluation of a potent small molecule CRM1 inhibitor for its selective ablation of extranodal NK/T cell lymphoma
    1
    1. scibot 15 Nov 2023
      RRID:CVCL_0030

      DOI: 10.7554/eLife.80625

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    ncbi.nlm.nih.gov/pmc/articles/PMC10637774/
  5. www.nature.com www.nature.com
    SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase
    1
    1. scibot 15 Nov 2023
      CVCL_0030

      DOI: 10.1038/s41467-023-43027-2

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    nature.com/articles/s41467-023-43027-2
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target
    2
    1. scibot 03 Nov 2023
      RRID:CVCL_0030

      DOI: 10.1158/2643-3230.BCD-22-0086

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      DOI: 10.1158/2643-3230.BCD-22-0086

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    ncbi.nlm.nih.gov/pmc/articles/PMC10150294/
  7. www.sciencedirect.com www.sciencedirect.com
    Gadd45β is critical for regulation of type I interferon signaling by facilitating G3BP-mediated stress granule formation
    1
    1. scibot 03 Nov 2023
      RRID:CVCL_0030

      DOI: 10.1016/j.celrep.2023.113358

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    sciencedirect.com/science/article/pii/S2211124723013700
  8. 52.53.155.43 52.53.155.43
    Molecular Oncology - 2023 - Pohlers - Th17 cells target the metabolic miR‐142‐5p succinate dehydrogenase subunit C D SDHC-html.html
    1
    1. scibot 03 Nov 2023
      RRID:CVCL_0030

      DOI: 10.1002/1878-0261.13546

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    52.53.155.43/a186f6fbd2a3289ac6933335bf9b0efbe74c0f93/Molecular Oncology - 2023 - Pohlers - Th17 cells target the metabolic miR-142-5p succinate dehydrogenase subunit C D SDHC-html.html
  9. www.embopress.org www.embopress.org
    Phosphatase specificity principles uncovered by MRBLE:Dephos and global substrate identification
    1
    1. scibot 03 Nov 2023
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      DOI: 10.15252/msb.202311782

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    embopress.org/doi/10.15252/msb.202311782
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The PMA phorbol ester tumor promoter increases canonical Wnt signaling via macropinocytosis
    1
    1. scibot 02 Nov 2023
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      DOI: 10.7554/eLife.89141

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    ncbi.nlm.nih.gov/pmc/articles/PMC10615368/
  11. Oct 2023
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity
    1
    1. scibot 31 Oct 2023
      RRID:CVCL_0030

      DOI: 10.1038/s41467-023-42342-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10611716/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The chromatin network helps prevent cancer-associated mutagenesis at transcription-replication conflicts
    1
    1. scibot 31 Oct 2023
      RRID:CVCL_0030

      DOI: 10.1038/s41467-023-42653-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC10613258/
  14. www.sciencedirect.com www.sciencedirect.com
    Single-nucleus RNA sequencing reveals heterogenous microenvironments and specific drug response between cervical squamous cell carcinoma and adenocarcinoma
    1
    1. scibot 28 Oct 2023
      RRID: CVCL_0030

      DOI: 10.1016/j.ebiom.2023.104846

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    sciencedirect.com/science/article/pii/S2352396423004127
  15. www.sciencedirect.com www.sciencedirect.com
    Human MCTS1-dependent translation of JAK2 is essential for IFN-γ immunity to mycobacteria
    1
    1. scibot 28 Oct 2023
      RRID:CVCL_0030

      DOI: 10.1016/j.cell.2023.09.024

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    sciencedirect.com/science/article/pii/S0092867423010784
  16. www.sciencedirect.com www.sciencedirect.com
    Lactate activates the mitochondrial electron transport chain independently of its metabolism
    1
    1. scibot 28 Oct 2023
      RRID:CVCL_0030

      DOI: 10.1016/j.molcel.2023.09.034

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    sciencedirect.com/science/article/pii/S1097276523008006
  17. www.sciencedirect.com www.sciencedirect.com
    Highly efficient cellular expression of circular mRNA enables prolonged protein expression
    1
    1. scibot 28 Oct 2023
      RRID:CVCL_0030

      DOI: 10.1016/j.chembiol.2023.09.015

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    sciencedirect.com/science/article/pii/S2451945623003343
  18. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 27 Oct 2023
      RRID:CVCL_0030

      DOI: 10.1111/bph.16203

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16203
  19. www.sciencedirect.com www.sciencedirect.com
    A PINK1 input threshold arises from positive feedback in the PINK1/Parkin mitophagy decision circuit
    1
    1. scibot 27 Oct 2023
      RRID:CVCL_0030

      DOI: 10.1016/j.celrep.2023.113260

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    sciencedirect.com/science/article/pii/S221112472301272X
  20. www.sciencedirect.com www.sciencedirect.com
    An activity-based functional test for identifying homologous recombination deficiencies across cancer types in real time
    1
    1. scibot 27 Oct 2023
      RRID:CVCL_0030

      DOI: 10.1016/j.xcrm.2023.101247

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    sciencedirect.com/science/article/pii/S266637912300424X
  21. www.sciencedirect.com www.sciencedirect.com
    Tumor-resident Lactobacillus iners confer chemoradiation resistance through lactate-induced metabolic rewiring
    1
    1. scibot 27 Oct 2023
      RRID:CVCL_0030

      DOI: 10.1016/j.ccell.2023.09.012

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    sciencedirect.com/science/article/pii/S1535610823003288
  22. link.springer.com link.springer.com
    Comparative genomic analysis of Mycoplasma related to cell culture for infB gene-based loop-mediated isothermal amplification
    1
    1. scibot 26 Oct 2023
      RRID: CVCL_0030

      DOI: 10.1007/s11274-023-03794-y

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    link.springer.com/article/10.1007/s11274-023-03794-y
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
    1
    1. scibot 20 Oct 2023
      RRID:CVCL_0030

      DOI: 10.1158/0008-5472.CAN-22-1337

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    ncbi.nlm.nih.gov/pmc/articles/PMC10570680/
  24. 52.53.155.43 52.53.155.43
    Blocking oligomerization is the most viable strategy to inhibit STING
    1
    1. scibot 20 Oct 2023
      CVCL_0030

      DOI: 10.1101/2023.08.11.553045

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    52.53.155.43/b51af3efb3ab194b2ea96b77566b6b4cbbb36c40/2023.08.11.553045v1.full-html.html
  25. www.sciencedirect.com www.sciencedirect.com
    Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy
    1
    1. scibot 13 Oct 2023
      CVCL_0030

      DOI: 10.1016/j.molcel.2023.09.007

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    sciencedirect.com/science/article/pii/S1097276523007025
  26. www.nature.com www.nature.com
    Revealing invisible cell phenotypes with conditional generative modeling
    1
    1. scibot 13 Oct 2023
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      DOI: 10.1038/s41467-023-42124-6

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    nature.com/articles/s41467-023-42124-6
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sequence-directed concentration of G protein-coupled receptors in COPII vesicles
    1
    1. scibot 07 Oct 2023
      ATCCCat# CRM-CCL-2

      DOI: 10.1016/j.isci.2023.107969

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    ncbi.nlm.nih.gov/pmc/articles/PMC10551652/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Schlafen-5 inhibits LINE-1 retrotransposition
    1
    1. scibot 07 Oct 2023
      RRID:CVCL_0030

      DOI: 10.1016/j.isci.2023.107968

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    ncbi.nlm.nih.gov/pmc/articles/PMC10551903/
  29. dx.doi.org dx.doi.org
    Piperacetazine directly binds to the PAX3::FOXO1 fusion protein and inhibits its transcriptional activity.
    1
    1. scibot 07 Oct 2023
      RRID:CVCL_0030

      DOI: 10.1158/2767-9764.CRC-23-0119

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    dx.doi.org/10.1158/2767-9764.CRC-23-0119
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hierarchical Phosphorylation of HOXB13 by mTOR Dictates Its Activity and Oncogenic Function in Prostate Cancer
    1
    1. scibot 06 Oct 2023
      RRID:CVCL_0030

      DOI: 10.1158/1541-7786.MCR-23-0086

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    ncbi.nlm.nih.gov/pmc/articles/PMC10544006/
  31. 52.53.155.43 52.53.155.43
    s41586-023-06657-6_reference-html.html
    1
    1. scibot 06 Oct 2023
      RRID:CVCL_0030

      DOI: 10.1038/s41586-023-06657-6

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    52.53.155.43/0f3eb7b8d15ef36be47b7c18ecdf1d19ad34ca1a/s41586-023-06657-6_reference-html.html
  32. www.biorxiv.org www.biorxiv.org
    Regulation of human interferon signaling by transposon exonization
    1
    1. scibot 05 Oct 2023
      RRID:CVCL_0030

      DOI: 10.1101/2023.09.11.557241

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    biorxiv.org/content/10.1101/2023.09.11.557241v1
  33. www.embopress.org www.embopress.org
    Hypoxia activates SREBP2 through Golgi disassembly in bone marrow-derived monocytes for enhanced tumor growth
    1
    1. scibot 03 Oct 2023
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      DOI: 10.15252/embj.2023114032

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    embopress.org/doi/10.15252/embj.2023114032
  34. Sep 2023
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hydrogen peroxide-dependent oxidation of ERK2 within its D-recruitment site alters its substrate selection
    2
    1. scibot 30 Sep 2023
      RRID:CVCL_0030

      DOI: 10.1016/j.isci.2023.107817

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      RRID:CVL-0030

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    ncbi.nlm.nih.gov/pmc/articles/PMC10514464/
  36. www.sciencedirect.com www.sciencedirect.com
    ActuAtor, a Listeria-inspired molecular tool for physical manipulation of intracellular organizations through de novo actin polymerization
    1
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      DOI: 10.1016/j.celrep.2023.113089

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    sciencedirect.com/science/article/pii/S2211124723011002
  37. www.sciencedirect.com www.sciencedirect.com
    Dysregulation of the Progranulin-driven Autophagy-lysosomal Pathway Mediates Secretion of the Nuclear Protein TDP-43
    1
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      RRID:CVCL_0030

      DOI: 10.1016/j.jbc.2023.105272

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    sciencedirect.com/science/article/pii/S0021925823023001
  38. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.16205

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16205
  39. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Benvenutti-html.html
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    1. scibot 29 Sep 2023
      RRID:CVCL_0030

      DOI: 10.1111/bph.16244

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    52.53.155.43/2fb911e91cc1c91b83ee8089957e7ad3829339b4/British J Pharmacology - 2023 - Benvenutti-html.html
  40. www.nature.com www.nature.com
    Defining the condensate landscape of fusion oncoproteins
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    1. scibot 29 Sep 2023
      RRID:CVCL_0030

      DOI: 10.1038/s41467-023-41655-2

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    nature.com/articles/s41467-023-41655-2
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic association of the intramembrane proteases SPPL2a/b and their substrates with tetraspanin-enriched microdomains
    1
    1. scibot 23 Sep 2023
      RRID:CVCL_0030

      DOI: 10.1016/j.isci.2023.107819

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    ncbi.nlm.nih.gov/pmc/articles/PMC10509304/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ESRRB inhibits the TGF-β signaling pathway to drive cell proliferation in cervical cancer
    1
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      RRID:CVCL_0030

      DOI: 10.1158/0008-5472.CAN-23-0067

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    ncbi.nlm.nih.gov/pmc/articles/PMC10502452/
  43. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Yin-html.html
    1
    1. scibot 16 Sep 2023
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    m6A RNA methylation orchestrates transcriptional dormancy during paused pluripotency
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    TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation
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    Sources of Calcium at Connexin 36 Gap Junctions in the Retina
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    MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy
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    exo-FISH: Protocol for detecting DNA breaks in repetitive regions of mammalian genomes
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    Exosomal release of the virus-encoded chemokine receptor US28 contributes to chemokine scavenging
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    Identification of an Imidazopyridine-based Compound as an Oral Selective Estrogen Receptor Degrader for Breast Cancer Therapy
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    FUBP1 is a general splicing factor facilitating 3′ splice site recognition and splicing of long introns
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    Aurora A polyubiquitinates the BRCA1-interacting protein OLA1 to promote centrosome maturation
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    A spatially defined human Notch receptor interaction network reveals Notch intracellular storage and Ataxin-2-mediated fast recycling
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    Chemogenetic regulation of the TARP-lipid interaction mimics LTP and reversibly modifies behavior
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    Formation of clathrin-pits and ATP-independent cholesterol-dependent tubules initiates mechano-regulation on de-adhesion
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Incorporation of genome-bound cellular proteins into HIV-1 particles regulates viral infection
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    The RIG-I agonist M8 triggers cell death and natural killer cell activation in human papillomavirus-associated cancer and potentiates cisplatin cytotoxicity
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    LINC00426, a novel m6A-regulated long non-coding RNA, induces EMT in cervical cancer by binding to ZEB1
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    The identification of high-performing antibodies for RNA-binding protein FUS for use in Western Blot, immunoprecipitation, and immunofluorescence
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    The Rho1 GTPase controls anillo-septin assembly to facilitate contractile ring closure during cytokinesis
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    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
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    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
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    Membrane shapers from two distinct superfamilies cooperate in the development of neuronal morphology
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    A Golgi-resident GPR108 cooperates with E3 ubiquitin ligase Smurf1 to suppress antiviral innate immunity
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    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
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    TRIM25-mediated ubiquitination of G3BP1 regulates the proliferation and migration of human neuroblastoma cells
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    The identification of high-performing antibodies for RNA-binding protein FUS for use in Western Blot, immunoprecipitation, and immunofluorescence
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    The identification of high-performing antibodies for Superoxide dismutase [Cu-Zn] 1 (SOD1) for use in Western blot, immunoprecipitation, and immunofluorescence
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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tfl deletion induces extraordinary Cxcl13 secretion and cachexia in VavP-Bcl2 transgenic mice
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  87. dx.doi.org dx.doi.org
    LZTR1 mutation mediates oncogenesis through stabilization of EGFR and AXL
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  88. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Deubiquitinase USP9X loss sensitizes renal cancer cells to mTOR inhibition
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  89. www.sciencedirect.com www.sciencedirect.com
    Enteric viruses evoke broad host immune responses resembling those elicited by the bacterial microbiome
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  90. www.embopress.org www.embopress.org
    STAT1 is required to establish but not maintain interferon-γ-induced transcriptional memory
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  91. link.springer.com link.springer.com
    Post-transcriptional regulation of tumor suppressor gene lncRNA CARMN via m6A modification and miRNA regulation in cervical cancer
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GIPC3 couples to MYO6 and PDZ domain proteins, and shapes the hair cell apical region
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  93. www.sciencedirect.com www.sciencedirect.com
    The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins
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  94. www.science.org www.science.org
    Alternative splicing of GSDMB modulates killer lymphocyte–triggered pyroptosis
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  95. May 2023
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Golgi-IP, a tool for multimodal analysis of Golgi molecular content
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  97. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial Bcl-xL promotes brain synaptogenesis by controlling non-lethal caspase activation
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  98. link.springer.com link.springer.com
    Discovery of two new isoforms of the human DUT gene
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  99. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Antitumor activity of galaxamide involved in cell apoptosis and stemness by inhibiting Wnt/β-catenin pathway in cervical cancer
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  100. journals.biologists.com journals.biologists.com
    The Salmonella effector SifA initiates a kinesin-1 and kinesin-3 recruitment process mirroring that mediated by Arl8a/b
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  101. www.sciencedirect.com www.sciencedirect.com
    Adherens junctions stimulate and spatially guide integrin activation and extracellular matrix deposition
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    Amelioration of SARS-CoV-2 infection by ANO6 phospholipid scramblase inhibition
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  103. www.sciencedirect.com www.sciencedirect.com
    Hyperosmotic-stress-induced liquid-liquid phase separation of ALS-related proteins in the nucleus
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  104. www.sciencedirect.com www.sciencedirect.com
    A chemogenetic platform for controlling plasma membrane signaling and synthetic signal oscillation
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  105. www.nature.com www.nature.com
    Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance
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  106. www.biorxiv.org www.biorxiv.org
    Membrane binding of endocytic myosin-1s is inhibited by a class of ankyrin repeat proteins
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  107. Apr 2023
  108. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Deletion of the tyrosine phosphatase Shp2 in cervical cancer cells promotes reprogramming of glutamine metabolism
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  109. www.sciencedirect.com www.sciencedirect.com
    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
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  110. www.sciencedirect.com www.sciencedirect.com
    Salmonella invasion of a cell is self-limiting due to effector-driven activation of N-WASP
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  111. www.sciencedirect.com www.sciencedirect.com
    ZFP36-mediated mRNA decay regulates metabolism
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  112. www.nature.com www.nature.com
    Full-length circular RNA profiling by nanopore sequencing with CIRI-long
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  113. link.springer.com link.springer.com
    Possible frequent multiple mitochondrial DNA copies in a single nucleoid in HeLa cells
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  114. www.embopress.org www.embopress.org
    The CEP170B-KIF2A complex destabilizes microtubule minus ends to generate polarized microtubule network
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A general method for quantitative fractionation of mammalian cells
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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone H3 phospho-regulation by KimH3 in both interphase and mitosis
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  117. Mar 2023
  118. www.biorxiv.org www.biorxiv.org
    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteasome Inhibitors Silence Oncogenes in Multiple Myeloma through Localized Histone Deacetylase 3 Stabilization and Chromatin Condensation
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  120. www.sciencedirect.com www.sciencedirect.com
    Capture RIC-seq reveals positional rules of PTBP1-associated RNA loops in splicing regulation
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    Leaked genomic and mitochondrial DNA contribute to the host response to noroviruses in a STING-dependent manner
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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of IDH3α Enhanced the Efficacy of Chemoimmunotherapy by Regulating Acidic Tumor Microenvironments
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  123. www.biorxiv.org www.biorxiv.org
    The acetylase activity of Cdu1 protects Chlamydia effectors from degradation to regulate bacterial exit from infected cells
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  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GIPC3 couples to MYO6 and PDZ domain proteins and shapes the hair cell apical region
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  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutating novel interaction sites in NRP1 reduces SARS-CoV-2 spike protein internalization
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  126. www.sciencedirect.com www.sciencedirect.com
    A combinatorial approach to uncover an additional Integrator subunit
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    Generation of a set of induced pluripotent stem cell lines from two Alzheimer disease patients carrying APOE4 (MLUi007-J; MLUi008-A) and healthy old donors carrying APOE3 (MLUi009-A; MLUi010-B) to study APOE in aging and disease
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  128. www.sciencedirect.com www.sciencedirect.com
    Redox proteomics combined with proximity labeling enables monitoring of localized cysteine oxidation in cells
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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures of NF-κB p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel canonical and non-canonical viral antigens extend current targets for immunotherapy of HPV-driven cervical cancer
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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation in vertebrates
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    Illuminating cellular and extracellular vesicle-mediated communication via a split-Nanoluc reporter in vitro and in vivo
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    Cationic amphiphilic antihistamines inhibit STAT3 via Ca2+-dependent lysosomal H+ efflux
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  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species
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  141. 52.53.155.43 52.53.155.43
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    A bat MERS-like coronavirus circulates in pangolins and utilizes human DPP4 and host proteases for cell entry
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  143. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    Thyroid hormones regulate Zfp423 expression in regionally distinct adipose depots through direct and cell-autonomous action
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  146. Jan 2023
  147. www.nature.com www.nature.com
    Design and construction of a microfluidics workstation for high-throughput multi-wavelength fluorescence and transmittance activated droplet analysis and sorting
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    The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria
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    Peptides from human BNIP5 and PXT1 and non-native binders of pro-apoptotic BAK can directly activate or inhibit BAK-mediated membrane permeabilization
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    Loss of RanGAP1 drives chromosome instability and rapid tumorigenesis of osteosarcoma
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    Cytosolic DNA sensing by cGAS/STING promotes TRPV2-mediated Ca2+ release to protect stressed replication forks
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    Centromeres as universal hotspots of DNA breakage, driving RAD51-mediated recombination during quiescence
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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    DIAPH3 condensates formed by liquid-liquid phase separation act as a regulatory hub for stress-induced actin cytoskeleton remodeling
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    The Novel Nucleoside Analogue ProTide NUC-7738 Overcomes Cancer Resistance Mechanisms In Vitro and in a First-In-Human Phase I Clinical Trial
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  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Metabolic enzyme UAP1 mediates IRF3 pyrophosphorylation to facilitate innate immune response
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    A minimal construct of nuclear-import receptor Karyopherin-β2 defines the regions critical for chaperone and disaggregation activity
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    Genome Editing Is Induced in a Binary Manner in Single Human Cells
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    Mitochondrial cristae architecture protects against mtDNA release and inflammation
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    Lactate-dependent chaperone-mediated autophagy induces oscillatory HIF-1α activity promoting proliferation of hypoxic cells
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    MOSPD2 is an endoplasmic reticulum–lipid droplet tether functioning in LD homeostasis
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  167. Nov 2022
  168. www.mdpi.com www.mdpi.com
    Chlamydial Infection-Dependent Synthesis of Sphingomyelin as a Novel Anti-Chlamydial Target of Ceramide Mimetic Compounds
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    Structural insights into caspase ADPR deacylization catalyzed by a bacterial effector and host calmodulin
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    LPA maintains innate antiviral immunity in a pro-active state via STK38L-mediated IRF3 Ser303 phosphorylation
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    Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins
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    Mitotic phosphorylation inhibits the Golgi mannosidase MAN1A1
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    Anti-CD19 chimeric antigen receptor T cells secreting anti-PD-L1 single-chain variable fragment attenuate PD-L1 mediated T cell inhibition
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  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol for base resolution mapping of ac4C using RedaC:T-seq
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    Translocation of nuclear chromatin distribution to the periphery reflects dephosphorylated threonine-821/826 of the retinoblastoma protein (pRb) in T24 cells treated with Bacillus Calmette–Guérin
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  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of phosphorylation site on PARP1 mediating its cytosolic translocation in virus-infected HeLa cells
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  177. www.nature.com www.nature.com
    A nascent peptide code for translational control of mRNA stability in human cells
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  178. www.nature.com www.nature.com
    SETD2 transcriptional control of ATG14L/S isoforms regulates autophagosome–lysosome fusion
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  179. www.researchsquare.com www.researchsquare.com
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  180. www.sciencedirect.com www.sciencedirect.com
    Bortezomib inhibits ZIKV/DENV by interfering with viral polyprotein cleavage via the ERAD pathway
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    Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses
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    LncRNA CCTT-mediated RNA-DNA and RNA-protein interactions facilitate the recruitment of CENP-C to centromeric DNA during kinetochore assembly
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    Acute depletion of human core nucleoporin reveals direct roles in transcription control but dispensability for 3D genome organization
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  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FAM57A (Family with Sequence Similarity 57 Member A) Is a Cell-Density-Regulated Protein and Promotes the Proliferation and Migration of Cervical Cancer Cells
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  185. rupress.org rupress.org
    Mitoguardin-2–mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation
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  186. Oct 2022
  187. brieflands.com brieflands.com
    Investigation of Curcumin-Loaded OA400 Nanoparticle’s Effect on the Expression of E6 and E7 Human Papilloma-Virus Oncogenes and P53 and Rb Factors in HeLa Cell Line
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  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HPV16 E7 Nucleotide Variants Found in Cancer-Free Subjects Affect E7 Protein Expression and Transformation
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  189. www.sciencedirect.com www.sciencedirect.com
    Alternative cleavage and polyadenylation generates downstream uncapped RNA isoforms with translation potential
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    Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells
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  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SERINC proteins potentiate antiviral type I IFN production and proinflammatory signaling pathways
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  192. www.sciencedirect.com www.sciencedirect.com
    Mechanisms and significance of tissue-specific MICU regulation of the mitochondrial calcium uniporter complex
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    Calcium transients on the ER surface trigger liquid-liquid phase separation of FIP200 to specify autophagosome initiation sites
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  194. www.tandfonline.com www.tandfonline.com
    Circ_0072995 drives cervical cancer development by regulating the miR-29a/WDR5 axis
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  195. www.sciencedirect.com www.sciencedirect.com
    Essential role for epithelial HIF-mediated xenophagy in control of Salmonella infection and dissemination
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  196. Sep 2022
  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Methanol extraction revealed anticancer compounds Quinic Acid, 2(5H)‑Furanone and Phytol in Andrographis paniculata
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  198. www.sciencedirect.com www.sciencedirect.com
    ER-Golgi-localized proteins TMED2 and TMED10 control the formation of plasma membrane lipid nanodomains
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    A new monoclonal antibody enables BAR analysis of subcellular importin β1 interactomes
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  200. link.springer.com link.springer.com
    Alpha-mangostin inhibits viral replication and suppresses nuclear factor kappa B (NF-κB)-mediated inflammation in dengue virus infection
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  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Coxsackievirus B infections are common in Cystic Fibrosis and experimental evidence supports protection by vaccination
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  202. elifesciences.org elifesciences.org
    Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells
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    Engineered fast-dissociating antibody fragments for multiplexed super-resolution microscopy
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  204. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Dickkopf-1 (Dkk1) expression is repressed by oncogenic HPVs and regulates the Cisplatin sensitivity of HPV-positive cancer cells in a JNK-dependent manner
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    Filopodial adhesive force in discrete nodes revealed by integrin molecular tension imaging
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    Target protein localization and its impact on PROTAC-mediated degradation
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    S1-END-seq reveals DNA secondary structures in human cells
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    Ku proteins promote DNA binding and condensation of cyclic GMP-AMP synthase
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    m1A and m6A modifications function cooperatively to facilitate rapid mRNA degradation
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    The human mitochondrial genome contains a second light strand promoter
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