1,874 Matching Annotations
  1. Sep 2025
  2. www.biorxiv.org www.biorxiv.org
    Mitochondrial proteostatic stress disrupts mitoribosome biogenesis and translation
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    biorxiv.org/content/10.1101/2025.09.05.673478v1
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    c-Met inhibitor NVP-BVU972 induces antiviral protection and suppresses NF-κB-mediated inflammation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12426891/
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    PPM1D is directly degraded by proteasomes in a ubiquitination-independent manner through its carboxyl-terminal region
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    jbiomedsci.biomedcentral.com/articles/10.1186/s12929-025-01185-z
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    A rapid imaging-based screen for induced-proximity degraders identifies a potent degrader of oncoprotein SKP2
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    nature.com/articles/s41587-025-02793-8
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    Connexin 43 drives glioblastoma cancer stem cell phenotypes through a WNK lysine-deficient protein kinase 1-c-MYC signaling axis
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    sciencedirect.com/science/article/pii/S2211124725010745
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    Phosphatidylserine-positive extracellular vesicles for detecting multiple operable cancers
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    sciencedirect.com/science/article/pii/S2211124725010307
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    The E3 ubiquitin ligase SIAH1 targets a bacterial pore-forming toxin to facilitate xenophagy
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    sciencedirect.com/science/article/pii/S2211124725010289
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    Chlorella-based bioactive oxygen generator for sustained tumor hypoxia alleviation and combined-modality tumor therapy
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    sciencedirect.com/science/article/pii/S0021979725023914
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    Coordination of autophagosome closure and release by the Alzheimer’s disease-associated protein BIN1
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    Targeting FSP1 to induce ferroptosis in chromophobe renal cell carcinoma
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    nature.com/articles/s41388-025-03562-2
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    Event-triggered MINFLUX microscopy: smart microscopy to catch and follow rare events
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    Development of a cyst-targeted therapy for polycystic kidney disease using an antagonistic dimeric IgA monoclonal antibody against cMET
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    PKD3 localizes to late endosomes to maintain Rab7-dependent endolysosomal homeostasis
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    YTHDF3 recognizes DNA N6-methyladenine and recruits ALKBH1 for 6mA removal from genomic DNA | The EMBO Journal
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    Endogenous YAP/TAZ partitioning in TEAD condensates orchestrates the Hippo response
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    A Commander-independent function of COMMD3 in endosomal trafficking
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    The antitumor effect of tlr4 inhibition in head and neck cancer cell lines
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    Caulerpin suppresses tumor-associated angiogenesis and tumor growth via Hippo signaling in cervical cancer
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    Hypoxia-Induced PRMT1 Lactylation Drives Vimentin Arginine Asymmetric Dimethylation in Tumor Metastasis
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  21. Aug 2025
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    Uncovering phenotypic inheritance from single cells with Microcolony-seq
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    Design of a selective peptide inhibitor targeting KDM5C demethylase activity
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    CDKL5 regulates the initiation of retrograde axonal transport through CLIP170–dynactin complex formation
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    Structural basis of poxvirus fusion regulation and anti-A16/G9 antibody-mediated neutralization and protection
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    Coordinated protein modules define DNA damage responses to carboplatin at single-cell resolution in human ovarian carcinoma models
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    KIDINS220 and InsP8 safeguard the stepwise regulation of phosphate exporter XPR1
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    TCF25 serves as a nutrient sensor to orchestrate metabolic adaptation and cell death by enhancing lysosomal acidification under glucose starvation
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    NAIP/NLRC4 inflammasome dynamics in murine enteroids are tuned by NAIP ligand concentration and epithelial cell differentiation
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    Imaging Interorganelle Phospholipid Transport by Extended Synaptotagmins Using Bioorthogonally Tagged Lipids
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    Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection
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    Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection
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    Optineurin Localization at the Centrosome, Spindle, and Midbody Implies Its Role in Cell Division
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    Ubiquitination of the histone variant mH2A1.2 prevents toxic RAD18 accumulation at a subset of genomic loci upon replication stress
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    pubs.acs.org/doi/10.1021/acs.analchem.5c03362
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NIPSNAP1 and NIPSNAP2 Act as “Eat Me” Signals for Mitophagy
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    Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses
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    Live-cell 3D-SIM of Rift Valley fever virus NSs filaments reveals a polygonal web architecture
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    biorxiv.org/content/10.1101/2025.07.30.667610v1
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    Integrator promotes the association of TFIID and RNA polymerase II to maintain pluripotency during development
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    A sensitive orange fluorescent calcium ion indicator for imaging neural activity
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    Combining Multiplexed CRISPR/Cas9-Nickase and PARP Inhibitors Efficiently and Precisely Targets Cancer Cells
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    Distinct 2-phenyl-imidazo[1, 2α] pyridine derivatives drive ER degradation and selectively impair proliferation of ER+ breast cancer cells via the aryl hydrocarbon receptor
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    Transient Catalase Immobilization for Cytoprotection during H2O2-Mediated Cell-Laden Hydrogel Fabrication
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    AI-directed voxel extraction and volume EM identify intrusions as sites of mitochondrial contact
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  63. Jul 2025
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A conserved CENP-E region mediates BubR1-independent recruitment to the outer corona at mitotic onset
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    Identification of CNOT1-CCR4-NOT as a suppressor of 53BP1-p53-p21 signaling
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    Legionella effector LpPIP recruits protein phosphatase 1 to the mitochondria to induce dephosphorylation of outer membrane proteins
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    Lycium barbarum Glycopeptide Inhibits Colorectal Cancer Cell Proliferation via Activating p53/p21 Pathway and Inducing Cellular Senescence
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    LncRNA CARMN inhibits cervical cancer cell growth via the miR-92a-3p/BTG2/Wnt/β-catenin axis
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    Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice
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    biorxiv.org/content/10.1101/2025.07.23.666448v1
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    A trans-kingdom T6SS RNase effector targeting both prokaryotic and host cells for pathogenesis
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    The Hippo pathway kinase MST1 mediates a feedback loop to maintain NLRP3 inflammasome homeostasis
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    Enhancing transcriptome mapping with rapid PRO-seq profiling of nascent RNA
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    Modular DNA barcoding of nanobodies enables multiplexed in situ protein imaging and high-throughput biomolecule detection
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    A new paradigm of islet adaptations in human pregnancy: insights from immunohistochemistry and proteomics
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    Direct interaction of HMGB1 with SARS-CoV-2 facilitates its infection via RAGE-dependent endocytosis
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    Sigma1 Receptor Modulates Plasma Membrane and Mitochondrial Peroxiporins
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    Small molecule UCM05 inhibits HSV-2 infection via targeting viral glycoproteins and fatty acid synthase with potentiating antiviral immunity
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    Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and shape their functional biology
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    science.org/doi/10.1126/sciadv.adu6354
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    A biotin-HaloTag ligand enables efficient affinity capture of protein variants from live cells
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    Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and shape their functional biology
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    Nostoc commune-derived scytonemin induced mitochondrial cell death in leukemia models
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    Enrichable cross-linkers for mapping direct protein interactions
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    Endolysosomal damage surveillance enables rapid inflammasome sensing of pathogens
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    FMRP drives mRNP targets into translationally silenced complexes
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    Graft-seq precisely maps RNA modifications via site-specific chemical grafting strategy
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    An alternate receptor for adeno-associated viruses
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    A guide to selecting high-performing antibodies for Stearoyl-CoA desaturase (SCD1) (UniProt ID: O00767) for use in western blot, immunoprecipitation, and immunofluorescence
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    Protocol for induction and study of DNA double-strand breaks in mammalian cells using PALM microdissection and expansion microscopy
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