1,107 Matching Annotations
  1. Oct 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hypoxia Induces Immunosuppression by Silencing STING in Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12498107/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Overexpression of RUNX2 promotes breast cancer multi-organ metastasis through stabilizing c-Myc
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    pmc.ncbi.nlm.nih.gov/articles/PMC12501288/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12515706/
  5. www.sciencedirect.com www.sciencedirect.com
    Tuning insulin receptor signaling using de novo-designed agonists
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    sciencedirect.com/science/article/pii/S1097276525007804
  6. www.biorxiv.org www.biorxiv.org
    Mapping the Subtype-Specific PARP1 ADP-ribosylated Proteome in Breast Cancer Cells
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    biorxiv.org/content/10.1101/2025.09.30.679484v1
  7. www.biorxiv.org www.biorxiv.org
    ACSS2-Mediated Metabolic-Epigenetic Crosstalk Drives Fulvestrant Resistance and Represents a Novel Therapeutic Target
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    biorxiv.org/content/10.1101/2025.09.23.678089v1
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Janus Face of SPAG6: Inducing EMT in Luminal Breast Cancer Cells Amidst Widespread Expression Loss in Breast Tumours
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    pmc.ncbi.nlm.nih.gov/articles/PMC12510430/
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    PHF19 drives the formation of PRC2 clusters to enhance motility in TNBC cells
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    sciencedirect.com/science/article/pii/S2211124725011623
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    YEATS4 reads histone crotonylation to promote fatty acid metabolism and cancer cell stemness
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    sciencedirect.com/science/article/pii/S2211124725011714
  11. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Laeverin is Cell-Surface Target for Liquid-Phase Metastasizing Cancer Cells
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511349
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antineoplastic Activity of a Novel Trispecific Single-Chain Antibody Targeting the hERG1/β1 Integrin Complex and TRAIL Receptors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485380/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bone-Induced Her2 Promotes Secondary Metastasis in HR+/Her2− Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11964846/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DEC1 promotes breast cancer bone metastasis through transcriptional activation of CXCR4
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    pmc.ncbi.nlm.nih.gov/articles/PMC12481698/
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    Inter- and intra-tumoral ALDH1 heterogeneity in breast cancer identifies therapeutic opportunities for ALDH1A-specific inhibitors
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    sciencedirect.com/science/article/pii/S2451945625002685
  16. Sep 2025
  17. www.sciencedirect.com www.sciencedirect.com
    Engineering unnatural amino acids in peptide linkers enables cathepsin-selective antibody-drug conjugates for HER2-positive breast cancer
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    sciencedirect.com/science/article/pii/S0168365925008818
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    Safe immunosuppression-resistant pan-cancer immunotherapeutics by velcro-like density-dependent targeting of tumor-associated carbohydrate antigens
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    sciencedirect.com/science/article/pii/S0092867425010323
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhancing the in vitro anticancer efficacy of Paclitaxel against triple-negative breast cancer via an exopolysaccharide from a haloalkaliphilic archaeal strain
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    pmc.ncbi.nlm.nih.gov/articles/PMC12457646/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phase Ib Study of Pembrolizumab in Combination with Intratumoral Injection of Clostridium novyi-NT in Patients with Advanced Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12434394/
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    Loss of estrogen receptor alpha promotes distant metastasis through epithelial-mesenchymal transition in luminal-type breast cancer
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    sciencedirect.com/science/article/pii/S092544392500403X
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    PDE7A inhibition suppresses triple-negative breast cancer by attenuating de novo pyrimidine biosynthesis
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    sciencedirect.com/science/article/pii/S266637912500429X
  23. www.mdpi.com www.mdpi.com
    Effective Reduction in Nuclear DNA Contamination Allows Sensitive Mitochondrial DNA Methylation Determination by LC-MS/MS
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    mdpi.com/1422-0067/26/18/8864
  24. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225018310-main-html.html
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  25. www.authorea.com www.authorea.com
    Hispidulin Inhibits Metastasis of Triple Negative Breast Cancer by Promoting MDM2-mediated Apelin Degradation
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    authorea.com/users/962058/articles/1331009-hispidulin-inhibits-metastasis-of-triple-negative-breast-cancer-by-promoting-mdm2-mediated-apelin-degradation
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    Chiral 1,3,5-Triazines as Potential EGFR Inhibitors: Pharmacophore Modeling, Synthesis, Molecular Docking, Molecular Dynamics Simulation, and Anticancer Evaluation
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202501632
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    Phosphatidylserine-positive extracellular vesicles for detecting multiple operable cancers
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    sciencedirect.com/science/article/pii/S2211124725010307
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The desmosome-intermediate filament system facilitates mechanotransduction at adherens junctions for epithelial homeostasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11387132/
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    Chemotherapy modulation by a cancer-associated microbiota metabolite
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    sciencedirect.com/science/article/pii/S2405471225002303
  30. www.biorxiv.org www.biorxiv.org
    The tumor suppressor CYLD acts as a deubiquitinase for mTOR to constrain its activity
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    biorxiv.org/content/10.1101/2025.09.01.673523v1
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Drug-Repurposing Screen Identifies Thiostrepton as a Novel Regulator of the Tumor Suppressor DAB2IP
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    pmc.ncbi.nlm.nih.gov/articles/PMC12384208/
  32. www.biorxiv.org www.biorxiv.org
    CDK4/6 inhibition induces a DNA damage-independent senescence-associated secretory phenotype driven by delayed activation of NF-κB
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    biorxiv.org/content/10.1101/2025.08.25.672139v1
  33. Aug 2025
  34. www.science.org www.science.org
    Diverse oncogenes use common mechanisms to drive growth of major forms of human cancer
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    science.org/doi/10.1126/sciadv.adt1798
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    Adenosine kinase and ADAL coordinate detoxification of modified adenosines to safeguard metabolism
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    sciencedirect.com/science/article/pii/S0092867425008633
  36. www.tandfonline.com www.tandfonline.com
    EpCAM-targeted near-infrared photoimmunotherapy (NIR-PIT) for the treatment of breast cancer
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    tandfonline.com/doi/full/10.1080/07853890.2025.2540599
  37. www.biorxiv.org www.biorxiv.org
    Estrogen Receptor Enhancers Sensitive to Low Doses of Hormone Specify Distinct Molecular and Biological Outcomes
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    biorxiv.org/content/10.1101/2025.08.08.669412v1
  38. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Programmable Nanodevice and Amplifier Module-Based DNA Cascaded Logic Circuits for Breast Tumor Cell Subtype Discrimination
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.202502784
  39. www.cell.com www.cell.com
    RNA Pol II inhibition activates cell death independently from the loss of transcription
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    cell.com/cell/abstract/S0092-8674(25)00856-6
  40. 52.53.155.43 52.53.155.43
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    Inhibition of tumor cell macropinocytosis driver DHODH reverses immunosuppression and overcomes anti-PD1 resistance
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    sciencedirect.com/science/article/pii/S107476132500322X
  42. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Endogenous Fluorescence Labeling of Extracellular Vesicles with a Hydrophilic Cyanine Dye via Caveolin-1 Dependent Endocytosis
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/adhm.202502680
  43. www.science.org www.science.org
    AND-1 is a critical regulator of R-loop dynamics and a target to overcome endocrine resistance
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    science.org/doi/10.1126/sciadv.adv2453
  44. www.sciencedirect.com www.sciencedirect.com
    Building simplified cancer subtyping and prediction models with glycan gene signatures
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    sciencedirect.com/science/article/pii/S2667237525001766
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AND-1 is a critical regulator of R-loop dynamics and a target to overcome endocrine resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12327453/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tissue-dependent mechanosensing by cells derived from human tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12328224/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phase Ib Trial of Fulvestrant, Palbociclib and Erdafitinib, a pan-FGFR Tyrosine Kinase Inhibitor, in HR+/HER2- Metastatic Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12326521/
  48. www.biorxiv.org www.biorxiv.org
    Distinct 2-phenyl-imidazo[1, 2α] pyridine derivatives drive ER degradation and selectively impair proliferation of ER+ breast cancer cells via the aryl hydrocarbon receptor
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    biorxiv.org/content/10.1101/2025.07.28.666967v1
  49. Jul 2025
  50. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    3D-Printed Unibody Microfluidic Devices for Organ-on-Chip Applications
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    advanced.onlinelibrary.wiley.com/doi/10.1002/admt.202501056
  51. www.tandfonline.com www.tandfonline.com
    Sophoridine inhibits proliferation and migration by targeting PIM1 in breast cancer
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    tandfonline.com/doi/abs/10.1080/13880209.2025.2537123
  52. www.sciencedirect.com www.sciencedirect.com
    Tumor-specific CD8 T cell characterization in HR+ breast cancer reveals an impaired antitumoral response in patients with lymph node metastasis
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    sciencedirect.com/science/article/pii/S2666379125003258
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A new paradigm of islet adaptations in human pregnancy: insights from immunohistochemistry and proteomics
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    pmc.ncbi.nlm.nih.gov/articles/PMC12280027/
  54. 52.53.155.43 52.53.155.43
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  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MSN/STAT3 drives cancer stemness and chemoresistance via IL-6/LPAR1 ligand receptor complex in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12281688/
  56. www.mdpi.com www.mdpi.com
    ERRα and HIF-1α Cooperate to Enhance Breast Cancer Aggressiveness and Chemoresistance Under Hypoxic Conditions
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    mdpi.com/2072-6694/17/14/2382
  57. rupress.org rupress.org
    A biotin-HaloTag ligand enables efficient affinity capture of protein variants from live cells
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    rupress.org/jcb/article/224/8/e202410025/278122/A-biotin-HaloTag-ligand-enables-efficient-affinity
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    Mitochondrial ROS inhibition prevents doxorubicin-induced breast cancer cell migration and invasion
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    sciencedirect.com/science/article/pii/S2589004225012921
  59. www.biorxiv.org www.biorxiv.org
    Salmonella hijacks a host glucose transporter for intravacuolar proliferation
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    biorxiv.org/content/10.1101/2025.06.10.658782v1
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70075
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptional repression of SOX2 by p53 in cancer cells regulates cell identity and migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12232590/
  62. www.nature.com www.nature.com
    Physicochemical characterization and biological evaluation of amorphous solid dispersions of an anticancerous drug: Erlotinib HCl
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    nature.com/articles/s41598-025-07692-1
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    18F-FLT PET, a Noninvasive Pharmacodynamic Biomarker of Tumor Cell Proliferation, Detected Differential Response to Various Cyclin-Dependent Kinase (CDK) Inhibitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214877/
  64. aacrjournals.org aacrjournals.org
    Development of a Novel DNA Mono-alkylator Platform for Antibody Drug Conjugates
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    aacrjournals.org/mct/article/23/4/541/741864/Development-of-a-Novel-DNA-Mono-alkylator-Platform
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214879/
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Evofosfamide Enhances Sensitivity of Breast Cancer Cells to Apoptosis and Natural-Killer-Cell-Mediated Cytotoxicity Under Hypoxic Conditions
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    pmc.ncbi.nlm.nih.gov/articles/PMC12191244/
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Long-term treatment with benzodiazepines and related Z-drugs exacerbates breast cancer: clinical evidence and molecular mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC12206364/
  68. Jun 2025
  69. www.sciencedirect.com www.sciencedirect.com
    Altered cofactor recruitment and nucleosome dynamics underlie bisphenol A’s impact on ERα-mediated transcriptional bursting
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    A bedside-to-bench translational analysis of NF1 alterations and CDK4/6 inhibitor resistance in hormone receptor-positive metastatic breast cancer
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    sciencedirect.com/science/article/pii/S2352396425002725
  71. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70079
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70077
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70049
  74. journals.sagepub.com journals.sagepub.com
    Anticancer Effect of Pinostrobin on Human Breast Cancer Cells Through Regulation of Epithelial Mesenchymal Transition
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    journals.sagepub.com/doi/full/10.1177/15347354251341438
  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An Acrolein-Based Drug Delivery System Enables Tumor-Specific Sphingosine-1-Phosphate Targeting in Breast Cancer without Lymphocytopenia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12174973/
  76. www.sciencedirect.com www.sciencedirect.com
    Microcurrent stimulation induces cell death in p53-mutant and 5-FU-resistant breast cancer
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    sciencedirect.com/science/article/pii/S0021925825022641
  77. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    EMT-associated bias in the Parsortix® system observed with pancreatic cancer cell lines
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70066
  78. www.nature.com www.nature.com
    PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer
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    nature.com/articles/s41388-025-03468-z
  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting Oncofoetal Chondroitin Sulphate Allows Identification of Tumour‐Derived Extracellular Vesicles
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    pmc.ncbi.nlm.nih.gov/articles/PMC12173530/
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    The evolutionarily conserved PRP4K-CHMP4B/vps32 splicing circuit regulates autophagy
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    sciencedirect.com/science/article/pii/S2211124725006412
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pleiotropic Effects of Metformin on the Chemotherapy Response of HPV‐Positive Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12169209/
  82. 52.53.155.43 52.53.155.43
    Comparative Function Analysis of Self-amplifying mRNA and Self-amplifying DNA
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  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcription factor occupancy limits DNA methylation and determines ICAM1 expression in breast cancer: TF binding limits DNA methylation and regulates ICAM1 level
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    pmc.ncbi.nlm.nih.gov/articles/PMC12130730/
  84. link.springer.com link.springer.com
    Targeted destruction of follicle stimulating hormone receptor-positive cancer cells in vitro and in vivo by a lytic peptide Phor21-FSHβ conjugate
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    link.springer.com/article/10.1186/s10020-025-01292-5
  85. www.cell.com www.cell.com
    Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming
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    cell.com/cell-metabolism/abstract/S1550-4131(25)00265-7
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    Exploring the Impact of Phenanthroline-based Glycoconjugated Ru(II) Polypyridyl Photosensitizers on Metastasis-related Processes”
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    Mechanism by which the molecular glue-like verteporfin induces IRE1α dimerization and activation to synergize with AKT inhibition in breast cancer
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