480 Matching Annotations
  1. Sep 2024
  2. aacrjournals.org aacrjournals.org
    Squalene epoxidase metabolic dependency is a targetable vulnerability in castration-resistant prostate cancer
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    aacrjournals.org/cancerres/article/82/17/3032/708286/Squalene-Epoxidase-Metabolic-Dependency-Is-a
  3. 52.53.155.43 52.53.155.43
    The effect of baseline O2 conditions on the response of prostate cancer cells to hypoxia
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    52.53.155.43/450c4ecfd2324159c1bf6d34b6f73a75b512ce38/alva-et-al-2024-the-effect-of-baseline-o2-conditions-on-the-response-of-prostate-cancer-cells-to-hypoxia-html.html
  4. journals.physiology.org journals.physiology.org
    The effect of baseline O2 conditions on the response of prostate cancer cells to hypoxia
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    journals.physiology.org/doi/10.1152/ajpcell.00155.2024
  5. www.sciencedirect.com www.sciencedirect.com
    PLXNA1 confers enzalutamide resistance in prostate cancer via AKT signaling pathway
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    sciencedirect.com/science/article/pii/S1476558624000897
  6. Aug 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10641717/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    WNT5A is a putative epi‐driver of prostate cancer metastasis to the bone
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    ncbi.nlm.nih.gov/pmc/articles/PMC11335815/
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    RPL22 is a tumor suppressor in MSI-high cancers and a splicing regulator of MDM4
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    sciencedirect.com/science/article/pii/S2211124724009720
  10. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Assessments of prostate cancer cell functions highlight differences between a pan-PI3K/mTOR inhibitor, gedatolisib, and single-node inhibitors of the PI3K/AKT/mTOR pathway
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13703
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lactate supports cell-autonomous ECM production to sustain metastatic behavior in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11315984/
  13. www.cell.com www.cell.com
    Germline-specific RNA helicase DDX4 forms cytoplasmic granules in cancer cells and promotes tumor growth
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    cell.com/cell-reports/fulltext/S2211-1247(24)00759-9
  14. www.cell.com www.cell.com
    Elevating PLK1 overcomes BETi resistance in prostate cancer via triggering BRD4 phosphorylation-dependent degradation in mitosis
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    cell.com/cell-reports/fulltext/S2211-1247(24)00760-5
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol to analyze the role of various metabolites in impacting global RNA 5-methylcytosine levels in cultured cells by dot blot
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    ncbi.nlm.nih.gov/pmc/articles/PMC10801338/
  16. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/4e85ba1ed1516c780407b3a64dcb4d2814a68c56/Molecular Oncology - 2023 - Gonthier - Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic mitochondrial tricarboxylic-html.html
  17. 52.53.155.43 52.53.155.43
    A novel EGFR Inhibitor, HNPMI regulates apoptosis and oncogenesis by modulating BCL-2/BAX and p53 in colon cancer
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    52.53.155.43/b51f94c49df43022b2f6198ee4b9b06582c4cb71/British J Pharmacology - 2023 - Kandhavelu - A novel EGFR Inhibitor HNPMI regulates apoptosis and oncogenesis by-html.html
  18. pubs.acs.org pubs.acs.org
    Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening
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    pubs.acs.org/doi/10.1021/acs.jmedchem.2c00864
  19. www.mdpi.com www.mdpi.com
    The Potential Tumor-Suppressor DHRS7 Inversely Correlates with EGFR Expression in Prostate Cancer Cells and Tumor Samples
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    mdpi.com/2072-6694/14/13/3074/htm
  20. Jul 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Investigating miR-6880-5p in extracellular vesicle from plasma as a prognostic biomarker in endocrine therapy-treated castration-resistant prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11285227/
  22. www.sciencedirect.com www.sciencedirect.com
    DNA damage-mediated FTO downregulation promotes CRPC progression by inhibiting FOXO3a via an m6A-dependent mechanism
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    sciencedirect.com/science/article/pii/S2589004224017309
  23. www.sciencedirect.com www.sciencedirect.com
    NAMPT-targeting PROTAC and nicotinic acid co-administration elicit safe and robust anti-tumor efficacy in NAPRT-deficient pan-cancers
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    sciencedirect.com/science/article/pii/S2451945624002083
  24. www.sciencedirect.com www.sciencedirect.com
    Prostate cancer detection through unbiased capture of methylated cell-free DNA
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    sciencedirect.com/science/article/pii/S2589004224015554
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive investigation in oncogenic functions and immunological roles of NCBP2 and its validation in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11283080/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identify Regulatory eQTLs by Multiome Sequencing in Prostate Single Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11213234/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNF185 control of COL3A1 expression limits prostate cancer migration and metastatic potential
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    ncbi.nlm.nih.gov/pmc/articles/PMC10841372/
  28. Jun 2024
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The TERT Promoter is Polycomb-Repressed in Neuroblastoma Cells with Long Telomeres
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    ncbi.nlm.nih.gov/pmc/articles/PMC11188873/
  30. www.mdpi.com www.mdpi.com
    Genomic Characterization of Preclinical Prostate Cancer Cell Line Models
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    mdpi.com/1422-0067/25/11/6111
  31. May 2024
  32. www.sciencedirect.com www.sciencedirect.com
    Inhibition of β2-adrenergic receptor regulates necroptosis in prostate cancer cell
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    sciencedirect.com/science/article/pii/S2405844024078964
  33. www.sciencedirect.com www.sciencedirect.com
    A unified mechanism for PARP inhibitor-induced PARP1 chromatin retention at DNA damage sites in living cells
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    sciencedirect.com/science/article/pii/S221112472400562X
  34. www.sciencedirect.com www.sciencedirect.com
    Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
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    sciencedirect.com/science/article/pii/S1097276524003241
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types
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    ncbi.nlm.nih.gov/pmc/articles/PMC11094420/
  36. link.springer.com link.springer.com
    WDR1 promotes prostate cancer progression through Wnt/β-catenin signaling
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    link.springer.com/article/10.1007/s12032-024-02388-4
  37. 52.53.155.43 52.53.155.43
    Therapeutic Implications of Ceritinib in Cholangiocarcinoma beyond ALK Expression and Mutation
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    52.53.155.43/3f07be0ebaa016d2b81ff2554651fc11f237f3a0/pharmaceuticals-17-00197-html.html
  38. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    ABCB1-mediated docetaxel resistance reversed by erastin in prostate cancer
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17135
  39. Apr 2024
  40. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Metabolic characterization of sphere-derived prostate cancer stem cells reveals aberrant urea cycle in stemness maintenance
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34967
  41. www.sciencedirect.com www.sciencedirect.com
    Repurposing AS1411 for constructing ANM-PROTACs
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    sciencedirect.com/science/article/pii/S2451945624001272
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer-associated fibroblasts promote enzalutamide resistance and PD-L1 expression in prostate cancer through CCL5-CCR5 paracrine axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11031830/
  43. aacrjournals.org aacrjournals.org
    Adipose triglyceride lipase is a therapeutic target in advanced prostate cancer that promotes metabolic plasticity
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    aacrjournals.org/cancerres/article/84/5/703/734936/Adipose-Triglyceride-Lipase-Is-a-Therapeutic
  44. www.sciencedirect.com www.sciencedirect.com
    Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum
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    sciencedirect.com/science/article/pii/S1534580724001801
  45. Mar 2024
  46. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  47. www.sciencedirect.com www.sciencedirect.com
    Acod1 expression in cancer cells promotes immune evasion through the generation of inhibitory peptides
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    sciencedirect.com/science/article/pii/S2211124724003127
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The RNA binding proteins LARP4A and LARP4B promote sarcoma and carcinoma growth and metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10963253/
  49. www.sciencedirect.com www.sciencedirect.com
    De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
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    sciencedirect.com/science/article/pii/S221112472400264X
  50. www.sciencedirect.com www.sciencedirect.com
    Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells
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    sciencedirect.com/science/article/pii/S1535610824000485
  51. Feb 2024
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An integrative proteomics approach identifies tyrosine kinase KIT as a therapeutic target for SPINK1-positive prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10879682/
  53. 52.53.155.43 52.53.155.43
    can-23-0555-html.html
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  54. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13614
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual inhibition of MEK and PI3Kβ/δ–a potential therapeutic strategy in PTEN-wild-type docetaxel-resistant metastatic prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10838968/
  56. www.sciencedirect.com www.sciencedirect.com
    SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion
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    sciencedirect.com/science/article/pii/S0092867424000102
  57. Jan 2024
  58. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Autophagy-dependent alternative splicing of ribosomal protein S24 produces a more stable isoform that aids in hypoxic cell survival
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14804
  59. www.sciencedirect.com www.sciencedirect.com
    Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer
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    sciencedirect.com/science/article/pii/S2666379123006171
  60. www.sciencedirect.com www.sciencedirect.com
    UCHL1 is a potential molecular indicator and therapeutic target for neuroendocrine carcinomas
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    sciencedirect.com/science/article/pii/S2666379123006109
  61. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Dual targeting of the androgen receptor and PI3K/AKT/mTOR pathways in prostate cancer models improves antitumor efficacy and promotes cell apoptosis
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13577
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Palmitic acid-activated GPRs/KLF7/CCL2 pathway is involved in the crosstalk between bone marrow adipocytes and prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10789002/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Detection of Extracellular Vesicle-Derived RNA as Potential Prostate Cancer Biomarkers: Role of Cancer-type SLCO1B3 and ABCC3
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    ncbi.nlm.nih.gov/pmc/articles/PMC10777027/
  64. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13563
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serine/threonine kinase 36 induced epithelial-mesenchymal transition promotes docetaxel resistance in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10771505/
  66. onlinelibrary.wiley.com onlinelibrary.wiley.com
    L-type amino acid transporter 1 inhibitor JPH203 prevents the growth of cabazitaxel-resistant prostate cancer by inhibiting cyclin-dependent kinase activity
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    onlinelibrary.wiley.com/doi/10.1111/cas.16062
  67. Dec 2023
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Cell Surface-Binding Antibody Atlas Nominates a MUC18-Directed Antibody–Drug Conjugate for Targeting Melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10646479/
  69. Nov 2023
  70. www.sciencedirect.com www.sciencedirect.com
    Prostate cancer cell-derived exosomal IL-8 fosters immune evasion by disturbing glucolipid metabolism of CD8+ T cell
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    sciencedirect.com/science/article/pii/S2211124723014365
  71. www.sciencedirect.com www.sciencedirect.com
    PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer
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    sciencedirect.com/science/article/pii/S2451945623003847
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Concurrent targeting of HDAC and PI3K to overcome phenotypic heterogeneity of castration-resistant and neuroendocrine prostate cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10658857/
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serine protease inhibitors decrease metastasis in prostate, breast, and ovarian cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10620120/
  74. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of the Cyclin K-CDK12 complex induces DNA damage and increases the effect of androgen deprivation therapy in prostate cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34778
  75. Oct 2023
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unrevealed roles of extracellular enolase‑1 (ENO1) in promoting glycolysis and pro‑cancer activities in multiple myeloma via hypoxia‑inducible factor 1α
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    ncbi.nlm.nih.gov/pmc/articles/PMC10568254/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting MALAT1 Augments Sensitivity to PARP Inhibition by Impairing Homologous Recombination in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10561629/
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hierarchical Phosphorylation of HOXB13 by mTOR Dictates Its Activity and Oncogenic Function in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10544006/
  79. Sep 2023
  80. www.biorxiv.org www.biorxiv.org
    A resource-based mechanistic framework for castration-resistant prostate cancer (CRPC)
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    biorxiv.org/content/10.1101/2023.09.19.558379v1
  81. www.sciencedirect.com www.sciencedirect.com
    Appraisals on the anticancer properties of Mentha species using bioassays and docking studies
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    sciencedirect.com/science/article/pii/S0926669023008932
  82. www.sciencedirect.com www.sciencedirect.com
    Combined CRISPRi and proteomics screening reveal a cohesin-CTCF-bound allele contributing to increased expression of RUVBL1 and prostate cancer progression
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    sciencedirect.com/science/article/pii/S0002929723002434
  83. journals.physiology.org journals.physiology.org
    Autocrine proteinase-activated receptor signaling in PC3 prostate cancer cells
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    journals.physiology.org/doi/10.1152/ajpcell.00382.2022
  84. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Kleszcz-html.html
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    52.53.155.43/bda5ca2ff5fc6352261b5aa6b5327e2f6367b095/British J Pharmacology - 2023 - Kleszcz-html.html
  85. Aug 2023
  86. www.sciencedirect.com www.sciencedirect.com
    Pivotal role of the ORAI3-STIM2 complex in the control of mitotic death and prostate cancer cell cycle progression.
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    sciencedirect.com/science/article/pii/S0143416023001057
  87. www.sciencedirect.com www.sciencedirect.com
    Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer
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    sciencedirect.com/science/article/pii/S0223523423006979
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10412558/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The long transcript of lncRNA TMPO-AS1 promotes bone metastases of prostate cancer by regulating the CSNK2A1/DDX3X complex in Wnt/β-catenin signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10403548/
  90. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Induction of more aggressive tumoral phenotypes in LNCaP and PC3 cells by serum exosomes from prostate cancer patients
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34673
  91. Jul 2023
  92. www.sciencedirect.com www.sciencedirect.com
    Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
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    sciencedirect.com/science/article/pii/S0092867423006967
  93. 52.53.155.43 52.53.155.43
    rational-design-and-development-of-selective-brd7-bromodomain-inhibitors-and-their-activity-in-prostate-cancer-html.html
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    52.53.155.43/fbc444166f400a01dc32894063d12537e1e236f5/rational-design-and-development-of-selective-brd7-bromodomain-inhibitors-and-their-activity-in-prostate-cancer-html.html
  94. Jun 2023
  95. www.sciencedirect.com www.sciencedirect.com
    Identification of XAF1 as an endogenous AKT inhibitor
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    sciencedirect.com/science/article/pii/S2211124723007015
  96. www.sciencedirect.com www.sciencedirect.com
    Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells
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    sciencedirect.com/science/article/pii/S2451945623001551
  97. www.sciencedirect.com www.sciencedirect.com
    Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer
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    sciencedirect.com/science/article/pii/S1535610823001836
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expression and Therapeutic Targeting of TROP-2 in Treatment-Resistant Prostate Cancer
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