437 Matching Annotations
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    Electrophilic compound screening identifies GPX4-dependent ferroptosis as a senescence vulnerability
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    nature.com/articles/s41556-026-01921-z
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    Biobank of genetically defined murine prostate cancer tumoroids uncovers oncogenic pathways and drug vulnerabilities driven by PTEN-loss
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    pmc.ncbi.nlm.nih.gov/articles/PMC13106976/
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    QW-5-70 targets the colchicine site and demonstrates antitumor activity in P-gp–overexpressing cancer models
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    aacrjournals.org/mct/article/doi/10.1158/1535-7163.MCT-25-1013/784192/QW-5-70-Targets-the-Colchicine-Site-and
  5. Apr 2026
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    Serotonin modulates lineage plasticity in neuroendocrine prostate cancer via epigenetic reprogramming
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    Anticancer Potential of Piericidin A1 and Derivatives Isolated From Streptomyces sp. Associated With Palythoa variabilis From Brazilian Reefs
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    pmc.ncbi.nlm.nih.gov/articles/PMC13095201/
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    Synergistic Treatment of Prostate Cancer and Multiple Myeloma using CD46-Targeted Radioimmunotherapy Antibody–Drug Conjugates
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    Proteomic Profiling Reveals How Physiological Media Reshape Cancer Cell Proteomes and Signaling Networks
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    Phenolic Profiles and Cytotoxic Activities of Methanolic Extracts From Eight Geranium L. Species
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202503814
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    Large-Scale Quantitative Morphometry of Platelet α-Granules via SIM Super-Resolution Microscopy for Cancer Liquid Biopsy
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    High-resolution functional mapping of androgen receptor variants
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    Betulinic acid induces lysosome-dependent death in prostate cancer by targeting DDX5
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    Astragaloside IV directly targets PPP1R14B to sensitize prostate cancer to anti-PD-1 immunotherapy by remodeling the CX3CL1/CD8+ T cell axis
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    Phase Separation of NFIB Suppresses SLC3A2-Mediated Ferroptosis in Castration-Resistant Prostate Cancer
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202515340
  16. Mar 2026
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    Early-stage multi-cancer detection through a plasma extracellular vesicle protein signature
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    Computational Simulation of the Bioactivity of Selected Compounds Derived From the Sapium and Salvias Genera as Anticancer Agents
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    onlinelibrary.wiley.com/doi/full/10.1155/bmri/4962249
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    In Vitro Cytotoxicity Assessment of Leaves of Tieghemella heckelii on Breast (MDA-MB-468), Liver (HepG2), and Prostate (PC3) Cancer Cell Lines
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    Dual regulation of CXCR6+CD8+ T cells modulates cytotoxic and exhaustion-associated programs during prostate cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12983932/
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    Targeting pre-existing club-like cells in prostate cancer potentiates androgen deprivation therapy
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    Chemical Constituents of Taxodium mucronatum (Cupressaceae) and Some of Its Endophytic Fungi, and Their In Silico and In Vitro Evaluations as SARS‐CoV‐2 Inhibitors and as Cytotoxic Agents
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    ASPARAGINE-RICH METASTATIC NICHES DRIVE PROSTATE CANCER ORGANOTROPISM BY ENABLING TRANSLATIONAL REWIRING TOWARD N-GLYCOSYLATED PROTEINS
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    Synergistic Efficacy of Gedatolisib and Darolutamide in Prostate Cancer to Overcome Resistance to Androgen-Targeted Therapy
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    OGDHL promotes prostate cancer progression and regulates neuroendocrine marker expression and nucleotide abundance
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  28. Feb 2026
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    Androgen Signaling Represses Homeobox C9, an Inhibitor of Androgen Receptor, in Prostate Cancer Cells
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    YEATS2 promotes DNA repair and induces anoikis resistance by enhancing chromatin accessibility to drive prostate cancer metastasis
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    RNAMaRs: an interpretable framework for inferring multivalent RNA Motifs and cognate Regulators of Splicing
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    VAV2 drives EGFR-mediated Rac1 responses in prostate cancer
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  38. Jan 2026
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    Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers
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    ETS-related gene as a key factor in curcumin inhibition of glucose metabolism in prostate cancer cells: an in vitro experimental study
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    Ubiquitination-directed cytosolic DNA degradation governs cGAS-STING-mediated immune response to DNA damage
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    Experimental and theoretical assessment of salvianolic acid B, ellagic acid, and phorbol esters as drug candidates against breast and prostate cancer
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    Morin hydrate alleviated cisplatin-induced testicular toxicity in rats via modulating NLRP3/NF-κB pathway
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  48. Dec 2025
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    Anti-mitotic agent SB-216 overcomes taxane resistance in castration-resistant prostate cancer and exhibits anti-tumour efficacy in pancreatic cancer
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    Osteocytes under Mechanical Loading Regulate PC‐3 Cancer Cell–Mineral Interactions during Early‐Stage Metastasis to Bone
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    biorxiv.org/content/10.64898/2025.12.03.690226v1
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    A novel biochip-based liquid biopsy for extracellular vesicle RNA detection in prostate cancer
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    tRF-21LeuTAA Promotes Oxidative Stress by Altering Glutathione Metabolic Enzymes to Support Prostate Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12666318/
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    PROCA11 early activation fuels prostate cancer neuroendocrine traits by regulating cell survival and migration
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  57. Nov 2025
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    Developing a therapeutic elastase that stimulates anti-tumor immunity by selectively killing cancer cells
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  61. Oct 2025
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    Germline-somatic liaison dictates cancer subtype via de novo steroid biosynthesis
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    Adversarial erasing enhanced multiple instance learning (siMILe): Discriminative identification of oligomeric protein structures in single molecule localization microscopy
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    biorxiv.org/content/10.1101/2025.09.29.679377v1
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    Laeverin is Cell-Surface Target for Liquid-Phase Metastasizing Cancer Cells
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    DGAT1 as a Racially Divergent Driver of Carcinoma-Associated Fibroblast Activation Drives Tumorigenic Pathways via ERK1/2 Signaling in Prostate Cancer
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    biorxiv.org/content/10.1101/2025.09.28.679062v1
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    Integrated Omics and Multi-Cohort Analyses Identify an Enhancer Variant Linking Ferroptosis to Precision Therapy in Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485374/
  68. Sep 2025
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    Colorectal cancer-associated PCBP1 mutations disrupt protein stability in a dominant negative manner
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    Induction of ferroptosis in prostate cancer by CCDC719-13 via TRIM21-mediated ubiquitination of SLC7A11
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    nature.com/articles/s41418-025-01580-x
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    KBTBD11 loss promotes AKT hyperactivation and therapeutic vulnerability in prostate cancer
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    nature.com/articles/s41388-025-03576-w
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    A smart gene circuit for precise regulation of tumor cell behavior
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    Disrupting the interaction between androgen receptor and its coregulator WDR77 delays the growth of treatment-resistant prostate cancer
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    sciencedirect.com/science/article/pii/S221112472501006X
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    Pan-carcinoma sialyl-Tn-targeting expands CAR therapy to solid tumors
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    Drug-Repurposing Screen Identifies Thiostrepton as a Novel Regulator of the Tumor Suppressor DAB2IP
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    pmc.ncbi.nlm.nih.gov/articles/PMC12384208/
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    The histone deacetylase inhibitor CG-745 enhances the radiosensitivity of prostate cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12409009/
  79. Aug 2025
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients
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    pmc.ncbi.nlm.nih.gov/articles/PMC12358827/
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical Evaluation of DB-1419, a Novel Bifunctional and Bispecific Anti–B7-H3 × PD-L1 Antibody–Drug Conjugate
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    pmc.ncbi.nlm.nih.gov/articles/PMC12351279/
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    Targeting oncofetal fibronectin and neuropilin-1 in solid tumors with PL2 peptide
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    pmc.ncbi.nlm.nih.gov/articles/PMC12340053/
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    Tissue-dependent mechanosensing by cells derived from human tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12328224/
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    Anticancer activity of triterpene glycosides from the sea star Solaster pacificus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12322260/
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A PSMA-targeted Tri-specific Killer Engager enhances NK cell cytotoxicity against prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11790377/
  86. Jul 2025
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Applying Unbiased, Functional Criteria Allows Selection of Novel Cyclic Peptides for Effective Targeted Drug Delivery to Malignant Prostate Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12298539/
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    Effective Treatment of Disseminated Prostate Cancer Using CD46-Targeted 225Ac Therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12260511/
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    Transcriptional profiling clarifies a program of enzalutamide extreme non-response in lethal prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12234718/
  90. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Annexin A1-Targeted d-Peptide-Monomethyl Auristatin E Conjugate Enhanced Antitumor Effect of Monomethyl Auristatin E for Chemotherapy of Prostate Cancer
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    onlinelibrary.wiley.com/doi/10.1002/pros.70007
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