831 Matching Annotations
  1. Feb 2025
  2. 52.53.155.43 52.53.155.43
    Novel Pannexin 1 isoform is increased in cancer
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    52.53.155.43/248e2b0e257da849dadde63c071f77bcede2b26b/2024.09.09.612143v3.full-html.html
  3. Jan 2025
  4. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17375
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chromosome mis-segregation triggers cell cycle arrest through a mechanosensitive nuclear envelope checkpoint
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    pmc.ncbi.nlm.nih.gov/articles/PMC11735390/
  6. www.sciencedirect.com www.sciencedirect.com
    Decoding the blueprint of receptor binding by filoviruses through large-scale binding assays and machine learning
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    sciencedirect.com/science/article/pii/S1931312824004839
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    TRMT1L-catalyzed m22G27 on tyrosine tRNA is required for efficient mRNA translation and cell survival under oxidative stress
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    sciencedirect.com/science/article/pii/S2211124724015183
  8. www.science.org www.science.org
    Chromatin conformation, gene transcription, and nucleosome remodeling as an emergent system
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    science.org/doi/10.1126/sciadv.adq6652
  9. elifesciences.org elifesciences.org
    A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms
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    elifesciences.org/articles/93183
  10. www.sciencedirect.com www.sciencedirect.com
    mTORC1 regulates the pyrimidine salvage pathway by controlling UCK2 turnover via the CTLH-WDR26 E3 ligase
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    sciencedirect.com/science/article/pii/S2211124724015304
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    C9ORF72 poly-PR induces TDP-43 nuclear condensation via NEAT1 and is modulated by HSP70 activity
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    sciencedirect.com/science/article/pii/S2211124724015249
  12. www.cell.com www.cell.com
    The differential interactomes of the KRAS splice variants identify BIRC6 as a ubiquitin ligase for KRAS4A
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    cell.com/cell-reports/fulltext/S2211-1247(24)01438-4
  13. www.tandfonline.com www.tandfonline.com
    Blocking autophagosome closure manifests the roles of mammalian Atg8-family proteins in phagophore formation and expansion during nutrient starvation
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    tandfonline.com/doi/full/10.1080/15548627.2024.2443300
  14. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.15081
  15. academic.oup.com academic.oup.com
    Synthetic anti-RNA antibody derivatives for RNA visualization in mammalian cells
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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkae1275/7935008
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    Identification of modulators of the ALT pathway through a native FISH-based optical screen
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    sciencedirect.com/science/article/pii/S2211124724014657
  17. Dec 2024
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Suppression of ADP-ribosylation reversal triggers cell vulnerability to alkylating agents
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    pmc.ncbi.nlm.nih.gov/articles/PMC11648251/
  19. www.sciencedirect.com www.sciencedirect.com
    G3BP1 promotes intermolecular RNA-RNA interactions during RNA condensation
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    sciencedirect.com/science/article/pii/S1097276524009171
  20. www.sciencedirect.com www.sciencedirect.com
    Dynamic control of RNA-DNA hybrid formation orchestrates DNA2 activation at stalled forks by RNAPII and DDX39A
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    sciencedirect.com/science/article/pii/S1097276524009894
  21. jhoonline.biomedcentral.com jhoonline.biomedcentral.com
    Tumor-derived G-CSF induces an immunosuppressive microenvironment in an osteosarcoma model, reducing response to CAR.GD2 T-cells
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    jhoonline.biomedcentral.com/articles/10.1186/s13045-024-01641-7
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ZBTB48 is a priming factor regulating B-cell-specific CIITA expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11649694/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphorylation of Optineurin by protein kinase D regulates Parkin-dependent mitophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11634986/
  24. www.sciencedirect.com www.sciencedirect.com
    PNKP safeguards stalled replication forks from nuclease-dependent degradation during replication stress
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    sciencedirect.com/science/article/pii/S2211124724014177
  25. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13773
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    Circular RNAs trigger nonsense-mediated mRNA decay
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    sciencedirect.com/science/article/pii/S109727652400947X
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines
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    pmc.ncbi.nlm.nih.gov/articles/PMC11621922/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optimized reporters for multiplexed detection of transcription factor activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11667439/
  29. www.sciencedirect.com www.sciencedirect.com
    Dual BACH1 regulation by complementary SCF-type E3 ligases
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    sciencedirect.com/science/article/pii/S0092867424013229
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    Reactive oxygen species control protein degradation at the mitochondrial import gate
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    sciencedirect.com/science/article/pii/S1097276524009092
  31. www.sciencedirect.com www.sciencedirect.com
    DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states
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    sciencedirect.com/science/article/pii/S1097276524009146
  32. www.sciencedirect.com www.sciencedirect.com
    The absence of telomerase leads to immune response and tumor regression in zebrafish melanoma
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    sciencedirect.com/science/article/pii/S221112472401386X
  33. www.nature.com www.nature.com
    ChromEMT: visualizing and reconstructing chromatin ultrastructure and 3D organization in situ
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    nature.com/articles/s41596-024-01071-2
  34. www.sciencedirect.com www.sciencedirect.com
    Nuclear Factor I family members are key transcription factors regulating gene expression
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    sciencedirect.com/science/article/pii/S1535947624001804
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC11671030/
  36. www.sciencedirect.com www.sciencedirect.com
    Unveiling the physiological impact of ESCRT-dependent autophagosome closure by targeting the VPS37A ubiquitin E2 variant-like domain
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    sciencedirect.com/science/article/pii/S2211124724013676
  37. Nov 2024
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CEP192 localises mitotic Aurora-A activity by priming its interaction with TPX2
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    pmc.ncbi.nlm.nih.gov/articles/PMC11574021/
  39. www.sciencedirect.com www.sciencedirect.com
    The molecular chaperone ALYREF promotes R-loop resolution and maintains genome stability
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    sciencedirect.com/science/article/pii/S0021925824024980
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    4’-Ethynyl-2’-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC11286238/
  41. www.nature.com www.nature.com
    Design, performance, processing, and validation of a pooled CRISPR perturbation screen for bacterial toxins
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    nature.com/articles/s41596-024-01075-y
  42. Oct 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Moesin contributes to heat shock gene response through direct binding to the Med15 subunit of the Mediator complex in the nucleus
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    ncbi.nlm.nih.gov/pmc/articles/PMC11444770/
  44. www.sciencedirect.com www.sciencedirect.com
    Pervasive mislocalization of pathogenic coding variants underlying human disorders
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    sciencedirect.com/science/article/pii/S0092867424010213
  45. Sep 2024
  46. www.nature.com www.nature.com
    Rapid generation of homozygous fluorescent knock-in human cells using CRISPR–Cas9 genome editing and validation by automated imaging and digital PCR screening
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    nature.com/articles/s41596-024-01043-6
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Strong activation of p53 by actinomycin D and nutlin-3a overcomes the resistance of cancer cells to the pro-apoptotic activity of the FAS ligand
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    ncbi.nlm.nih.gov/pmc/articles/PMC11416401/
  48. www.sciencedirect.com www.sciencedirect.com
    A TBK1-independent primordial function of STING in lysosomal biogenesis
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    sciencedirect.com/science/article/pii/S1097276524007032
  49. elifesciences.org elifesciences.org
    A mechanism in Agrin signaling revealed by a prevalent Rapsyn mutation in congenital myasthenic syndrome
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    elifesciences.org/articles/49180
  50. elifesciences.org elifesciences.org
    Agrin-Lrp4-Ror2 signaling regulates adult hippocampal neurogenesis in mice
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    elifesciences.org/articles/45303
  51. elifesciences.org elifesciences.org
    Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria
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    elifesciences.org/articles/34836
  52. www.sciencedirect.com www.sciencedirect.com
    C9orf72 Poly(PR) Dipeptide Repeats Disturb Biomolecular Phase Separation and Disrupt Nucleolar Function
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    sciencedirect.com/science/article/pii/S1097276519302230
  53. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S0092867418313084
  54. europepmc.org europepmc.org
    Untitled document
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    europepmc.org/articles/PMC5957528/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5957528/
  56. www.sciencedirect.com www.sciencedirect.com
    Protocol to study the direct binding of proteins to RNA:DNA hybrids or RNA-DNA chimeras in living cells using cross-linking immunoprecipitation
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    sciencedirect.com/science/article/pii/S266616672400457X
  57. www.sciencedirect.com www.sciencedirect.com
    A nature-inspired HIF stabilizer derived from a highland-adaptation insertion of plateau pika Epas1 protein
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    sciencedirect.com/science/article/pii/S2211124724010787
  58. www.sciencedirect.com www.sciencedirect.com
    Conserved cysteine-switches for redox sensing operate in the Cyclin-Dependent Kinase Inhibitor p21(CIP/KIP) Protein Family.
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    sciencedirect.com/science/article/pii/S0891584924006609
  59. www.sciencedirect.com www.sciencedirect.com
    A compact, versatile drug-induced splicing switch system with minimal background expression
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    sciencedirect.com/science/article/pii/S2667237524002157
  60. Aug 2024
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    R-loops and impaired autophagy trigger cGAS-dependent inflammation via micronuclei formation in Senataxin-deficient cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11335261/
  62. www.sciencedirect.com www.sciencedirect.com
    Condensate interfacial forces reposition DNA loci and probe chromatin viscoelasticity
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    sciencedirect.com/science/article/pii/S0092867424008286
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Casein kinase 1α mediates phosphorylation of the Merkel cell polyomavirus large T antigen for β-TrCP destruction complex interaction and subsequent degradation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11323502/
  64. www.sciencedirect.com www.sciencedirect.com
    Optogenetic control of kinesin-1, -2, -3 and dynein reveals their specific roles in vesicular transport
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    sciencedirect.com/science/article/pii/S2211124724010003
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Engineered Drug 3′UTRMYC1-18 Degrades the c-MYC-STAT5A/B-PD-L1 Complex In Vivo to Inhibit Metastatic Triple-Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11311709/
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    Structural requirements for activity of Mind bomb1 in Notch signaling
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    sciencedirect.com/science/article/pii/S0969212624002740
  67. www.sciencedirect.com www.sciencedirect.com
    RTEL1 helicase counteracts RAD51-mediated homologous recombination and fork reversal to safeguard replicating genomes
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    sciencedirect.com/science/article/pii/S2211124724009239
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    Detection of a Mitochondrial Fragmentation and Integrated Stress Response Using the Cell Painting Assay
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    sciencedirect.com/org/science/article/pii/S1520480424003053
  69. www.cell.com www.cell.com
    Neotelomeres and telomere-spanning chromosomal arm fusions in cancer genomes revealed by long-read sequencing
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    cell.com/cell-genomics/fulltext/S2666-979X(24)00172-1
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability
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    ncbi.nlm.nih.gov/pmc/articles/PMC11366124/
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MTF2 facilitates the advancement of osteosarcoma through mediating EZH2/SFRP1/Wnt signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11312803/
  72. www.sciencedirect.com www.sciencedirect.com
    Generation of densely labeled oligonucleotides for the detection of small genomic elements
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    sciencedirect.com/science/article/pii/S2667237524002133
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulating tumor-associated macrophage polarization by anti-maRCO mAb exerts anti-osteosarcoma effects through regulating osteosarcoma cell proliferation, migration and apoptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11290128/
  74. aacrjournals.org aacrjournals.org
    Piperacetazine directly binds to the PAX3::FOXO1 fusion protein and inhibits its transcriptional activity.
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    aacrjournals.org/cancerrescommun/article/3/10/2030/729478/Piperacetazine-Directly-Binds-to-the-PAX3-FOXO1
  75. www.science.org www.science.org
    Posttranslational modification of microtubules by the MATCAP detyrosinase
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    science.org/doi/10.1126/science.abn6020
  76. www.cell.com www.cell.com
    Parthenolide Destabilizes Microtubules by Covalently Modifying Tubulin
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    cell.com/current-biology/fulltext/S0960-9822(20)31768-1
  77. www.mdpi.com www.mdpi.com
    Diketopiperazine-Based, Flexible Tadalafil Analogues: Synthesis, Crystal Structures and Biological Activity Profile
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    mdpi.com/1420-3049/26/4/794/htm
  78. bio-protocol.org bio-protocol.org
    Protocol for Establishing a Multiplex Image-based Autophagy ...
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    bio-protocol.org/e2540
  79. Jul 2024
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of the main barriers to Ku accumulation in chromatin
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    ncbi.nlm.nih.gov/pmc/articles/PMC11411529/
  81. www.biorxiv.org www.biorxiv.org
    Click-chemistry-aided quantitation and sequencing of oxidized guanines and apurinic sites uncovers their transcription-linked strand bias in human cells
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    biorxiv.org/content/10.1101/2024.07.21.604463v1
  82. www.sciencedirect.com www.sciencedirect.com
    Loss of ZNF408 attenuates STING-mediated immune surveillance in breast carcinogenesis
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    sciencedirect.com/science/article/pii/S2589004224015013
  83. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    AXIN2 promotes degradation of AXIN1 through tankyrase in colorectal cancer cells
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    febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.17226
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Miga-mediated endoplasmic reticulum–mitochondria contact sites regulate neuronal homeostasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC7556861/
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterising replisome disassembly in human cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11269944/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC11240082/
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus by inducing high molecular weight RNP complexes
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    ncbi.nlm.nih.gov/pmc/articles/PMC11233918/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A high-throughput approach to identify BRCA1-downregulating compounds to enhance PARP inhibitor sensitivity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11238136/
  89. academic.oup.com academic.oup.com
    A RAD18–UBC13–PALB2–RNF168 axis mediates replication fork recovery in BRCA1-deficient cancer cells
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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkae563/7701480
  90. journals.asm.org journals.asm.org
    Casein kinase 1α mediates phosphorylation of the Merkel cell polyomavirus large T antigen for β-TrCP destruction complex interaction and subsequent degradation
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    journals.asm.org/doi/10.1128/mbio.01117-24
  91. Jun 2024
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 screening reveals a distinct class of MHC-I binders with precise HLA-peptide recognition
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    ncbi.nlm.nih.gov/pmc/articles/PMC11209011/
  93. www.nature.com www.nature.com
    An intermediate Rb–E2F activity state safeguards proliferation commitment
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    nature.com/articles/s41586-024-07554-2
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The TERT Promoter is Polycomb-Repressed in Neuroblastoma Cells with Long Telomeres
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    ncbi.nlm.nih.gov/pmc/articles/PMC11188873/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fully automated viability and toxicity screening—A reliable all‐in‐one attempt
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    ncbi.nlm.nih.gov/pmc/articles/PMC11193055/
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Illuminating Dark Chemical Matter Using the Cell Painting Assay
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    ncbi.nlm.nih.gov/pmc/articles/PMC11181314/
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-Molecule Inhibition of CBX4/7 Hypersensitises Homologous Recombination-Impaired Cancer to Radiation by Compromising CtIP-Mediated DNA End Resection
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  193. Aug 2023
  194. www.sciencedirect.com www.sciencedirect.com
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  195. www.science.org www.science.org
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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activator protein-1 (AP-1) signaling inhibits the growth of Ewing sarcoma cells in response to DNA replication stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC10434289/
  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  199. www.nature.com www.nature.com
    Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor
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  200. 52.53.155.43 52.53.155.43
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    SUMO-activated target traps (SATTs) enable the identification of a comprehensive E3-specific SUMO proteome
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  202. Jul 2023
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    Aurora A polyubiquitinates the BRCA1-interacting protein OLA1 to promote centrosome maturation
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    Protocol for automated multivariate quantitative-image-based cytometry analysis by fluorescence microscopy of asynchronous adherent cells
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  206. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  207. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    A chimeric human/dog-DNA vaccine against CSPG4 induces immunity with therapeutic potential in comparative preclinical models of osteosarcoma
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  209. Jun 2023
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    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
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  213. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
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