894 Matching Annotations
  1. Jul 2025
  2. journals.biologists.com journals.biologists.com
    Proteasome-dependent Orc6 removal from chromatin upon S-phase entry safeguards against minichromosome maintenance complex reloading and tetraploidy
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    journals.biologists.com/jcs/article/138/13/jcs263596/368530/Proteasome-dependent-Orc6-removal-from-chromatin
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    Protocol for induction and study of DNA double-strand breaks in mammalian cells using PALM microdissection and expansion microscopy
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    sciencedirect.com/science/article/pii/S2666166725003442
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    Specific GPCRs Elicit Unique Extracellular Vesicle MiRNA Array Signatures: An Exploratory Study
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    biorxiv.org/content/10.1101/2025.06.16.659918v1
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    Subcellular mass spectrometry imaging of lipids and nucleotides using transmission geometry ambient laser desorption and plasma ionisation
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    biorxiv.org/content/10.1101/2025.05.13.653655v1
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    Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression
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    science.org/doi/10.1126/science.adv2861
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    A lentiviral fluorescent reporter to study circadian rhythms in single cells
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    biorxiv.org/content/10.1101/2025.06.30.661926v1
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    Versatile enhancement of the killing potential of anti-cancer agents achieved by peptide mimetics of the PCNA interface towards specialized DNA polymerases
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    nature.com/articles/s41419-025-07812-9
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    Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses
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    science.org/doi/10.1126/sciimmunol.adr1105
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Histone Deacetylase Inhibitors Target DNA Replication Regulators and Replication Stress in Ewing Sarcoma Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12202856/
  11. Jun 2025
  12. www.sciencedirect.com www.sciencedirect.com
    Isoform-specific function of NSD3 in DNA replication stress confers resistance to PARP inhibitors in prostate cancer
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    sciencedirect.com/science/article/pii/S1097276525005040
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    The DNA replication checkpoint prevents PCNA/RFC depletion to protect forks from HLTF-induced collapse in human cells
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    sciencedirect.com/science/article/pii/S1097276525005027
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    Transferrin receptor controls both autophagosome formation and closure via phosphatidylinositol 3-phosphate synthesis
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    sciencedirect.com/science/article/pii/S1534580725003272
  15. www.cell.com www.cell.com
    Phase separation of TTBK2 and CEP164 is necessary for ciliogenesis
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    cell.com/cell-reports/fulltext/S2211-1247(25)00581-9
  16. journals.sagepub.com journals.sagepub.com
    Multi-omics Analysis of Histone-related Genes in Osteosarcoma: A Multidimensional Integrated Study Revealing Drug Sensitivity and Immune Microenvironment Characteristics
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    journals.sagepub.com/doi/full/10.1177/15330338251336275
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pleiotropic Effects of Metformin on the Chemotherapy Response of HPV‐Positive Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12169209/
  18. link.springer.com link.springer.com
    The puzzling regulation of the interferon signaling system by the p53 tumor suppressor protein
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    link.springer.com/article/10.1007/s00018-025-05763-0
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRAMP1-dependent histone H1 biogenesis is essential for topoisomerase II inhibitor tolerance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12240685/
  20. 52.53.155.43 52.53.155.43
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    Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming
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    cell.com/cell-metabolism/abstract/S1550-4131(25)00265-7
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Image-based identification and isolation of micronucleated cells to dissect cellular consequences
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    pmc.ncbi.nlm.nih.gov/articles/PMC12129451/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hypoxic HPV‐Positive Cancer Cells Are Particularly Sensitive to the Pro‐Senescent Effects of B‐MYB Repression Due to the Lack of Compensatory A‐MYB Induction
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    pmc.ncbi.nlm.nih.gov/articles/PMC12123558/
  24. May 2025
  25. www.nature.com www.nature.com
    Decoding post-transcriptional regulatory networks by RNA-linked CRISPR screening in human cells
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    nature.com/articles/s41592-025-02702-6
  26. pubs.acs.org pubs.acs.org
    Catalytic-Dependent Role of DNA Polymerase κ in Nucleotide Excision Repair
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    pubs.acs.org/doi/10.1021/acs.chemrestox.5c00085
  27. www.sciencedirect.com www.sciencedirect.com
    YTHDF1 differentiates the contributing roles of mTORC1 in aging
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    sciencedirect.com/science/article/pii/S1097276525004083
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    Multigenerational cell tracking of DNA replication and heritable DNA damage
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    nature.com/articles/s41586-025-08986-0
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    Tunable metastability of condensates reconciles their dual roles in amyloid fibril formation
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    sciencedirect.com/science/article/pii/S1097276525004162
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    MePCE promotes homologous recombination through coordinating R-loop resolution at DNA double-stranded breaks
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    Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates
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    sciencedirect.com/science/article/pii/S0092867425005094
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    The human proteome with direct physical access to DNA
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    sciencedirect.com/science/article/pii/S0092867425005070
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1-s2.0-S2589004225009605-main-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC12164204/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A conserved role for centriolar satellites in translation of centrosomal and ciliary proteins
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    pmc.ncbi.nlm.nih.gov/articles/PMC12094185/
  35. journals.sagepub.com journals.sagepub.com
    Multi-omics Analysis of Histone-related Genes in Osteosarcoma: A Multidimensional Integrated Study Revealing Drug Sensitivity and Immune Microenvironment Characteristics
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    journals.sagepub.com/doi/full/10.1177/15330338251336275
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    Integrative characterization of MYC RNA-binding function
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    sciencedirect.com/science/article/pii/S2666979X2500134X
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    An integrated proteomics approach identifies phosphorylation sites on viral and host proteins that regulate West Nile virus infection
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    sciencedirect.com/science/article/pii/S2211124725004991
  38. Apr 2025
  39. www.sciencedirect.com www.sciencedirect.com
    Aberrant phase separation drives membranous organelle remodeling and tumorigenesis
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    sciencedirect.com/science/article/pii/S1097276525003041
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    Loss of function of Atrx recapitulates phenotypes of alternative lengthening of telomeres in a primary mouse model of sarcoma
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    sciencedirect.com/science/article/pii/S2589004225006182
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    RNF144A-VRK2-G3BP1 axis regulates stress granule assembly
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    pmc.ncbi.nlm.nih.gov/articles/PMC11982375/
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    DM1 repeat-expanded RNAs confer RNA toxicity as individual nuclear-retained RNAs
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    sciencedirect.com/science/article/pii/S2211124725003535
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    Supra-second tracking and live-cell karyotyping reveal principles of mitotic chromosome dynamics
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    nature.com/articles/s41556-025-01637-6
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatial proteomics of ER tubules reveals CLMN, an ER-actin tether at focal adhesions that promotes cell migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12416146/
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An Aurora kinase A-BOD1L1-PP2A B56 axis promotes chromosome segregation fidelity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962599/
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    Deciphering UBE4B phosphorylation dynamics: a key mechanism in p53 accumulation and cancer cell response to DNA damage
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    nature.com/articles/s41420-025-02441-9
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    Genetically encoded reporters of actin filament organization in living cells and tissues
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    sciencedirect.com/science/article/pii/S0092867425002764
  48. Mar 2025
  49. www.sciencedirect.com www.sciencedirect.com
    TDP-43 seeding induces cytoplasmic aggregation heterogeneity and nuclear loss of function of TDP-43
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    sciencedirect.com/science/article/pii/S089662732500176X
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    Widespread variation in molecular interactions and regulatory properties among transcription factor isoforms
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    sciencedirect.com/science/article/pii/S1097276525001972
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    A niche driven mechanism determines response and a mutation-independent therapeutic approach for myeloid malignancies
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    sciencedirect.com/science/article/pii/S1535610825001084
  52. academic.oup.com academic.oup.com
    Homeodomain protein PRRX1 anchors the Ku heterodimers at DNA double-strand breaks to promote nonhomologous end-joining
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    academic.oup.com/nar/article/53/6/gkaf200/8089753
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    Distinct roles of SARS-CoV-2 N protein and NFP in host cell response modulation
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    sciencedirect.com/science/article/pii/S0022283625001603
  54. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Targeting Replication Fork Processing Synergizes with PARP Inhibition to Potentiate Lethality in Homologous Recombination Proficient Ovarian Cancers
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202410718
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The BLM-TOP3A-RMI1-RMI2 proximity map reveals that RAD54L2 suppresses sister chromatid exchanges
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    pmc.ncbi.nlm.nih.gov/articles/PMC11894219/
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    Protocol for single-cell analysis of DNA double-strand break production and repair in cell-cycle phases by automated high-content microscopy
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    sciencedirect.com/science/article/pii/S2666166725000681
  57. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70049
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Radiotherapy resistance driven by Asparagine endopeptidase through ATR pathway modulation in breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11866873/
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Discovery and characterization of a novel telomerase alternative splicing isoform that protects lung cancer cells from chemotherapy induced cell death
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    pmc.ncbi.nlm.nih.gov/articles/PMC11861669/
  60. Feb 2025
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Salicylate-Elicited Activation of AMP-Activated Protein Kinase Directly Triggers Degradation of C-Myc in Colorectal Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11854256/
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    OTUD6B regulates KIFC1-dependent centrosome clustering and breast cancer cell survival
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    pmc.ncbi.nlm.nih.gov/articles/PMC11850729/
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    Methionine intervention induces PD-L1 expression to enhance the immune checkpoint therapy response in MTAP-deleted osteosarcoma
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    sciencedirect.com/science/article/pii/S2666379125000503
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    Compositionally unique mitochondria in filopodia support cellular migration
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  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Circadian period is compensated for repressor protein turnover rates in single cells
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  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    E6AP is essential for the proliferation of HPV-positive cancer cells by preventing senescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC11805377/
  67. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Activating AMPK improves pathological phenotypes due to mtDNA depletion
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70006
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ultrasound-assisted synthesis of new bisphosphonate–betulin conjugates and preliminary evaluation of their cytotoxic activity
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  69. 52.53.155.43 52.53.155.43
    Novel Pannexin 1 isoform is increased in cancer
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  70. Jan 2025
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17375
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    Chromosome mis-segregation triggers cell cycle arrest through a mechanosensitive nuclear envelope checkpoint
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    pmc.ncbi.nlm.nih.gov/articles/PMC11735390/
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    Decoding the blueprint of receptor binding by filoviruses through large-scale binding assays and machine learning
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    sciencedirect.com/science/article/pii/S1931312824004839
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    TRMT1L-catalyzed m22G27 on tyrosine tRNA is required for efficient mRNA translation and cell survival under oxidative stress
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    sciencedirect.com/science/article/pii/S2211124724015183
  75. www.science.org www.science.org
    Chromatin conformation, gene transcription, and nucleosome remodeling as an emergent system
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    science.org/doi/10.1126/sciadv.adq6652
  76. elifesciences.org elifesciences.org
    A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms
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    elifesciences.org/articles/93183
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    mTORC1 regulates the pyrimidine salvage pathway by controlling UCK2 turnover via the CTLH-WDR26 E3 ligase
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    sciencedirect.com/science/article/pii/S2211124724015304
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    C9ORF72 poly-PR induces TDP-43 nuclear condensation via NEAT1 and is modulated by HSP70 activity
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    sciencedirect.com/science/article/pii/S2211124724015249
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    The differential interactomes of the KRAS splice variants identify BIRC6 as a ubiquitin ligase for KRAS4A
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    cell.com/cell-reports/fulltext/S2211-1247(24)01438-4
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    Blocking autophagosome closure manifests the roles of mammalian Atg8-family proteins in phagophore formation and expansion during nutrient starvation
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    tandfonline.com/doi/full/10.1080/15548627.2024.2443300
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.15081
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    Synthetic anti-RNA antibody derivatives for RNA visualization in mammalian cells
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    Identification of modulators of the ALT pathway through a native FISH-based optical screen
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  84. Dec 2024
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Suppression of ADP-ribosylation reversal triggers cell vulnerability to alkylating agents
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    G3BP1 promotes intermolecular RNA-RNA interactions during RNA condensation
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    Dynamic control of RNA-DNA hybrid formation orchestrates DNA2 activation at stalled forks by RNAPII and DDX39A
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  88. jhoonline.biomedcentral.com jhoonline.biomedcentral.com
    Tumor-derived G-CSF induces an immunosuppressive microenvironment in an osteosarcoma model, reducing response to CAR.GD2 T-cells
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  89. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ZBTB48 is a priming factor regulating B-cell-specific CIITA expression
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  90. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphorylation of Optineurin by protein kinase D regulates Parkin-dependent mitophagy
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    PNKP safeguards stalled replication forks from nuclease-dependent degradation during replication stress
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13773
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    Circular RNAs trigger nonsense-mediated mRNA decay
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  94. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines
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  95. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optimized reporters for multiplexed detection of transcription factor activity
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    Dual BACH1 regulation by complementary SCF-type E3 ligases
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    Temporal dynamics and stoichiometry in human Notch signaling from Notch synaptic complex formation to nuclear entry of the Notch intracellular domain
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  193. Mar 2024
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    FAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis
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    Stabilization of F-actin by Salmonella effector SipA resembles the structural effects of inorganic phosphate and phalloidin
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    Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity
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    Lysosomal damage sensing and lysophagy initiation by SPG20-ITCH
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  198. 52.53.155.43 52.53.155.43
    The immediate-early protein 1 of human herpesvirus 6B interacts with NBS1 and inhibits ATM signaling
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    52.53.155.43/85f3cfb5ea69a502f1e71c384533cb9dacfc2966/collin-et-al-2024-the-immediate-early-protein-1-of-human-herpesvirus-6b-interacts-with-nbs1-and-inhibits-atm-signaling-html.html
  199. www.embopress.org www.embopress.org
    RAD51 restricts DNA over-replication from re-activated origins
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    RAD51 restricts DNA over-replication from re-activated origins
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    HDAC5 enhances IRF3 activation and is targeted for degradation by protein C6 from orthopoxviruses including Monkeypox virus and Variola virus
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    Genome-scale requirements for dynein-based transport revealed by a high-content arrayed CRISPR screen
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    CDK-independent role of D-type cyclins in regulating DNA mismatch repair
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    Securin acetylation prevents precocious separase activation and premature sister chromatid separation
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    Non-canonical isoforms of the mRNA polyadenylation factor WDR33 regulate STING-mediated immune responses
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  206. Feb 2024
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    A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis
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    Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection
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    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
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    Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting
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