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Jun 2025
www.cell.com www.cell.com

Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming

1
1. scibot 11 Jun 2025
  
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  ATCCHTB-96
  
  DOI: 10.1016/j.cmet.2025.05.009
  
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cell.com/cell-metabolism/abstract/S1550-4131(25)00265-7
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Image-based identification and isolation of micronucleated cells to dissect cellular consequences

1
1. scibot 04 Jun 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.7554/eLife.101579
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12129451/
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Hypoxic HPV‐Positive Cancer Cells Are Particularly Sensitive to the Pro‐Senescent Effects of B‐MYB Repression Due to the Lack of Compensatory A‐MYB Induction

1
1. scibot 04 Jun 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.1002/jmv.70422
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12123558/
May 2025
www.nature.com www.nature.com

Decoding post-transcriptional regulatory networks by RNA-linked CRISPR screening in human cells

1
1. scibot 30 May 2025
  
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  CVCL_0042
  
  DOI: 10.1038/s41592-025-02702-6
  
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nature.com/articles/s41592-025-02702-6
pubs.acs.org pubs.acs.org

Catalytic-Dependent Role of DNA Polymerase κ in Nucleotide Excision Repair

1
1. scibot 29 May 2025
  
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  HTB 96
  
  DOI: 10.1021/acs.chemrestox.5c00085
  
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pubs.acs.org/doi/10.1021/acs.chemrestox.5c00085
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YTHDF1 differentiates the contributing roles of mTORC1 in aging

1
1. scibot 29 May 2025
  
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  ATCCHTB-96
  
  DOI: 10.1016/j.molcel.2025.05.003
  
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sciencedirect.com/science/article/pii/S1097276525004083
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Multigenerational cell tracking of DNA replication and heritable DNA damage

1
1. scibot 29 May 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.1038/s41586-025-08986-0
  
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nature.com/articles/s41586-025-08986-0
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Tunable metastability of condensates reconciles their dual roles in amyloid fibril formation

1
1. scibot 29 May 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.1016/j.molcel.2025.05.011
  
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sciencedirect.com/science/article/pii/S1097276525004162
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MePCE promotes homologous recombination through coordinating R-loop resolution at DNA double-stranded breaks

1
1. scibot 29 May 2025
  
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  CVCL_0042
  
  DOI: 10.1016/j.celrep.2025.115740
  
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sciencedirect.com/science/article/pii/S221112472500511X
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Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates

1
1. scibot 29 May 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.1016/j.cell.2025.04.039
  
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sciencedirect.com/science/article/pii/S0092867425005094
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The human proteome with direct physical access to DNA

1
1. scibot 29 May 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.1016/j.cell.2025.04.037
  
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sciencedirect.com/science/article/pii/S0092867425005070
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1-s2.0-S2589004225009605-main-html.html

2
1. scibot 23 May 2025
  
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  HTB-96
  
  DOI: 10.1016/j.isci.2025.112699
  
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  Curator: @sjvitug
  
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2. scibot 22 May 2025
  
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  ATCC HTB-96
  
  DOI: 10.1016/j.isci.2025.112699
  
  Resource: (RRID:CVCL_0042)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12164204/
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A conserved role for centriolar satellites in translation of centrosomal and ciliary proteins

1
1. scibot 23 May 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.1083/jcb.202408042
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12094185/
journals.sagepub.com journals.sagepub.com

Multi-omics Analysis of Histone-related Genes in Osteosarcoma: A Multidimensional Integrated Study Revealing Drug Sensitivity and Immune Microenvironment Characteristics

1
1. scibot 21 May 2025
  
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  CVCL_0042
  
  DOI: 10.1177/15330338251336275
  
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journals.sagepub.com/doi/full/10.1177/15330338251336275
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Integrative characterization of MYC RNA-binding function

1
1. scibot 19 May 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.1016/j.xgen.2025.100878
  
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sciencedirect.com/science/article/pii/S2666979X2500134X
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An integrated proteomics approach identifies phosphorylation sites on viral and host proteins that regulate West Nile virus infection

1
1. scibot 17 May 2025
  
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  ATCCHTB-96
  
  DOI: 10.1016/j.celrep.2025.115728
  
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sciencedirect.com/science/article/pii/S2211124725004991
Apr 2025
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Aberrant phase separation drives membranous organelle remodeling and tumorigenesis

1
1. scibot 24 Apr 2025
  
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  ATCCCat# HTB-96
  
  DOI: 10.1016/j.molcel.2025.04.001
  
  Resource: (RRID:CVCL_0042)
  
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sciencedirect.com/science/article/pii/S1097276525003041
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Loss of function of Atrx recapitulates phenotypes of alternative lengthening of telomeres in a primary mouse model of sarcoma

1
1. scibot 24 Apr 2025
  
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  U2OS
  
  DOI: 10.1016/j.isci.2025.112357
  
  Resource: (RRID:CVCL_0042)
  
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sciencedirect.com/science/article/pii/S2589004225006182
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

RNF144A-VRK2-G3BP1 axis regulates stress granule assembly

1
1. scibot 16 Apr 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.1038/s41420-025-02460-6
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11982375/
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DM1 repeat-expanded RNAs confer RNA toxicity as individual nuclear-retained RNAs

1
1. scibot 15 Apr 2025
  
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  ATCCHTB-96
  
  DOI: 10.1016/j.celrep.2025.115582
  
  Resource: (RRID:CVCL_0042)
  
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sciencedirect.com/science/article/pii/S2211124725003535
www.nature.com www.nature.com

Supra-second tracking and live-cell karyotyping reveal principles of mitotic chromosome dynamics

1
1. scibot 10 Apr 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.1038/s41556-025-01637-6
  
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nature.com/articles/s41556-025-01637-6
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Spatial proteomics of ER tubules reveals CLMN, an ER-actin tether at focal adhesions that promotes cell migration

1
1. scibot 05 Apr 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.1016/j.celrep.2025.115502
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12416146/
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An Aurora kinase A-BOD1L1-PP2A B56 axis promotes chromosome segregation fidelity

1
1. scibot 04 Apr 2025
  
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  U2OS
  
  DOI: 10.1016/j.celrep.2025.115317
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11962599/
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Deciphering UBE4B phosphorylation dynamics: a key mechanism in p53 accumulation and cancer cell response to DNA damage

1
1. scibot 03 Apr 2025
  
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  RRID: CVCL_0042
  
  DOI: 10.1038/s41420-025-02441-9
  
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  Curator: @dhovakimyan1
  
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  RRID:CVCL_0042 DOI:10.1038/s41420-025-02441-9
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nature.com/articles/s41420-025-02441-9
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Genetically encoded reporters of actin filament organization in living cells and tissues

1
1. scibot 03 Apr 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.1016/j.cell.2025.03.003
  
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sciencedirect.com/science/article/pii/S0092867425002764
Mar 2025
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TDP-43 seeding induces cytoplasmic aggregation heterogeneity and nuclear loss of function of TDP-43

1
1. scibot 29 Mar 2025
  
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  ATCCCat# HTB-96
  
  DOI: 10.1016/j.neuron.2025.03.004
  
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sciencedirect.com/science/article/pii/S089662732500176X
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Widespread variation in molecular interactions and regulatory properties among transcription factor isoforms

1
1. scibot 28 Mar 2025
  
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  ATCCHTB-96
  
  DOI: 10.1016/j.molcel.2025.03.004
  
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sciencedirect.com/science/article/pii/S1097276525001972
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A niche driven mechanism determines response and a mutation-independent therapeutic approach for myeloid malignancies

1
1. scibot 28 Mar 2025
  
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  ATCCHTB-96
  
  DOI: 10.1016/j.ccell.2025.03.007
  
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sciencedirect.com/science/article/pii/S1535610825001084
academic.oup.com academic.oup.com

Homeodomain protein PRRX1 anchors the Ku heterodimers at DNA double-strand breaks to promote nonhomologous end-joining

1
1. scibot 24 Mar 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.1093/nar/gkaf200
  
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academic.oup.com/nar/article/53/6/gkaf200/8089753
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Distinct roles of SARS-CoV-2 N protein and NFP in host cell response modulation

1
1. scibot 20 Mar 2025
  
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  ATCC HTB-96
  
  DOI: 10.1016/j.jmb.2025.169094
  
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sciencedirect.com/science/article/pii/S0022283625001603
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Targeting Replication Fork Processing Synergizes with PARP Inhibition to Potentiate Lethality in Homologous Recombination Proficient Ovarian Cancers

1
1. scibot 20 Mar 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.1002/advs.202410718
  
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advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202410718
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The BLM-TOP3A-RMI1-RMI2 proximity map reveals that RAD54L2 suppresses sister chromatid exchanges

1
1. scibot 18 Mar 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.1038/s44319-025-00374-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11894219/
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Protocol for single-cell analysis of DNA double-strand break production and repair in cell-cycle phases by automated high-content microscopy

1
1. scibot 06 Mar 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.1016/j.xpro.2025.103662
  
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sciencedirect.com/science/article/pii/S2666166725000681
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 04 Mar 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.1111/febs.70049
  
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febs.onlinelibrary.wiley.com/doi/10.1111/febs.70049
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Radiotherapy resistance driven by Asparagine endopeptidase through ATR pathway modulation in breast cancer

1
1. scibot 01 Mar 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.1186/s13046-025-03334-6
  
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  Curator: @evieth
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11866873/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Discovery and characterization of a novel telomerase alternative splicing isoform that protects lung cancer cells from chemotherapy induced cell death

1
1. scibot 01 Mar 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.1038/s41598-025-90639-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11861669/
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Salicylate-Elicited Activation of AMP-Activated Protein Kinase Directly Triggers Degradation of C-Myc in Colorectal Cancer Cells

1
1. scibot 27 Feb 2025
  
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  RRID:CVCL_0042
  
  DOI: 10.3390/cells14040294
  
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OTUD6B regulates KIFC1-dependent centrosome clustering and breast cancer cell survival

1
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Methionine intervention induces PD-L1 expression to enhance the immune checkpoint therapy response in MTAP-deleted osteosarcoma

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Compositionally unique mitochondria in filopodia support cellular migration

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Circadian period is compensated for repressor protein turnover rates in single cells

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E6AP is essential for the proliferation of HPV-positive cancer cells by preventing senescence

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Activating AMPK improves pathological phenotypes due to mtDNA depletion

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Ultrasound-assisted synthesis of new bisphosphonate–betulin conjugates and preliminary evaluation of their cytotoxic activity

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Novel Pannexin 1 isoform is increased in cancer

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Jan 2025
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FEBS Press

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Chromosome mis-segregation triggers cell cycle arrest through a mechanosensitive nuclear envelope checkpoint

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Decoding the blueprint of receptor binding by filoviruses through large-scale binding assays and machine learning

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TRMT1L-catalyzed m22G27 on tyrosine tRNA is required for efficient mRNA translation and cell survival under oxidative stress

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Chromatin conformation, gene transcription, and nucleosome remodeling as an emergent system

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A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms

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mTORC1 regulates the pyrimidine salvage pathway by controlling UCK2 turnover via the CTLH-WDR26 E3 ligase

1
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C9ORF72 poly-PR induces TDP-43 nuclear condensation via NEAT1 and is modulated by HSP70 activity

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The differential interactomes of the KRAS splice variants identify BIRC6 as a ubiquitin ligase for KRAS4A

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  HTB-96
  
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Blocking autophagosome closure manifests the roles of mammalian Atg8-family proteins in phagophore formation and expansion during nutrient starvation

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  HTB-96
  
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FEBS Press

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Synthetic anti-RNA antibody derivatives for RNA visualization in mammalian cells

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Identification of modulators of the ALT pathway through a native FISH-based optical screen

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Suppression of ADP-ribosylation reversal triggers cell vulnerability to alkylating agents

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G3BP1 promotes intermolecular RNA-RNA interactions during RNA condensation

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Dynamic control of RNA-DNA hybrid formation orchestrates DNA2 activation at stalled forks by RNAPII and DDX39A

1
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Tumor-derived G-CSF induces an immunosuppressive microenvironment in an osteosarcoma model, reducing response to CAR.GD2 T-cells

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ZBTB48 is a priming factor regulating B-cell-specific CIITA expression

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Phosphorylation of Optineurin by protein kinase D regulates Parkin-dependent mitophagy

2
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PNKP safeguards stalled replication forks from nuclease-dependent degradation during replication stress

1
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FEBS Press

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  DOI: 10.1002/1878-0261.13773
  
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Circular RNAs trigger nonsense-mediated mRNA decay

1
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  RRID:CVCL_0042
  
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Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines

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Optimized reporters for multiplexed detection of transcription factor activity

1
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  ATCCCat#HTB-96, RRID:CVCL_0042
  
  DOI: 10.1016/j.cels.2024.11.003
  
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Dual BACH1 regulation by complementary SCF-type E3 ligases

1
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  ATCCCat# HTB-96
  
  DOI: 10.1016/j.cell.2024.11.006
  
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Reactive oxygen species control protein degradation at the mitochondrial import gate

1
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  ATCCCat# HTB-96
  
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DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states

1
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  ATCCHTB-96
  
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The absence of telomerase leads to immune response and tumor regression in zebrafish melanoma

1
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  RRID:HTB-96
  
  DOI: 10.1016/j.celrep.2024.115035
  
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ChromEMT: visualizing and reconstructing chromatin ultrastructure and 3D organization in situ

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Nuclear Factor I family members are key transcription factors regulating gene expression

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The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo

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Unveiling the physiological impact of ESCRT-dependent autophagosome closure by targeting the VPS37A ubiquitin E2 variant-like domain

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CEP192 localises mitotic Aurora-A activity by priming its interaction with TPX2

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The molecular chaperone ALYREF promotes R-loop resolution and maintains genome stability

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4’-Ethynyl-2’-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress

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Design, performance, processing, and validation of a pooled CRISPR perturbation screen for bacterial toxins

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Moesin contributes to heat shock gene response through direct binding to the Med15 subunit of the Mediator complex in the nucleus

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Pervasive mislocalization of pathogenic coding variants underlying human disorders

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Rapid generation of homozygous fluorescent knock-in human cells using CRISPR–Cas9 genome editing and validation by automated imaging and digital PCR screening

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Strong activation of p53 by actinomycin D and nutlin-3a overcomes the resistance of cancer cells to the pro-apoptotic activity of the FAS ligand

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A TBK1-independent primordial function of STING in lysosomal biogenesis

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A mechanism in Agrin signaling revealed by a prevalent Rapsyn mutation in congenital myasthenic syndrome

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Agrin-Lrp4-Ror2 signaling regulates adult hippocampal neurogenesis in mice

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Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria

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C9orf72 Poly(PR) Dipeptide Repeats Disturb Biomolecular Phase Separation and Disrupt Nucleolar Function

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Untitled document

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Untitled document

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Untitled document

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Protocol to study the direct binding of proteins to RNA:DNA hybrids or RNA-DNA chimeras in living cells using cross-linking immunoprecipitation

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  RRID: CVCL_0042
  
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A nature-inspired HIF stabilizer derived from a highland-adaptation insertion of plateau pika Epas1 protein

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Conserved cysteine-switches for redox sensing operate in the Cyclin-Dependent Kinase Inhibitor p21(CIP/KIP) Protein Family.

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A compact, versatile drug-induced splicing switch system with minimal background expression

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R-loops and impaired autophagy trigger cGAS-dependent inflammation via micronuclei formation in Senataxin-deficient cells

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  U2OS
  
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Condensate interfacial forces reposition DNA loci and probe chromatin viscoelasticity

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Casein kinase 1α mediates phosphorylation of the Merkel cell polyomavirus large T antigen for β-TrCP destruction complex interaction and subsequent degradation

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Optogenetic control of kinesin-1, -2, -3 and dynein reveals their specific roles in vesicular transport

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The Engineered Drug 3′UTRMYC1-18 Degrades the c-MYC-STAT5A/B-PD-L1 Complex In Vivo to Inhibit Metastatic Triple-Negative Breast Cancer

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Structural requirements for activity of Mind bomb1 in Notch signaling

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RTEL1 helicase counteracts RAD51-mediated homologous recombination and fork reversal to safeguard replicating genomes

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Detection of a Mitochondrial Fragmentation and Integrated Stress Response Using the Cell Painting Assay

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Neotelomeres and telomere-spanning chromosomal arm fusions in cancer genomes revealed by long-read sequencing

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HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability

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MTF2 facilitates the advancement of osteosarcoma through mediating EZH2/SFRP1/Wnt signaling

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Generation of densely labeled oligonucleotides for the detection of small genomic elements

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Modulating tumor-associated macrophage polarization by anti-maRCO mAb exerts anti-osteosarcoma effects through regulating osteosarcoma cell proliferation, migration and apoptosis

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Piperacetazine directly binds to the PAX3::FOXO1 fusion protein and inhibits its transcriptional activity.

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Posttranslational modification of microtubules by the MATCAP detyrosinase

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Parthenolide Destabilizes Microtubules by Covalently Modifying Tubulin

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Diketopiperazine-Based, Flexible Tadalafil Analogues: Synthesis, Crystal Structures and Biological Activity Profile

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Protocol for Establishing a Multiplex Image-based Autophagy ...

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Identification of the main barriers to Ku accumulation in chromatin

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Click-chemistry-aided quantitation and sequencing of oxidized guanines and apurinic sites uncovers their transcription-linked strand bias in human cells

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Loss of ZNF408 attenuates STING-mediated immune surveillance in breast carcinogenesis

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AXIN2 promotes degradation of AXIN1 through tankyrase in colorectal cancer cells

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Miga-mediated endoplasmic reticulum–mitochondria contact sites regulate neuronal homeostasis

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Characterising replisome disassembly in human cells

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The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescence

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Multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus by inducing high molecular weight RNP complexes

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A high-throughput approach to identify BRCA1-downregulating compounds to enhance PARP inhibitor sensitivity

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A RAD18–UBC13–PALB2–RNF168 axis mediates replication fork recovery in BRCA1-deficient cancer cells

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Casein kinase 1α mediates phosphorylation of the Merkel cell polyomavirus large T antigen for β-TrCP destruction complex interaction and subsequent degradation

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CRISPR/Cas9 screening reveals a distinct class of MHC-I binders with precise HLA-peptide recognition

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An intermediate Rb–E2F activity state safeguards proliferation commitment

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The TERT Promoter is Polycomb-Repressed in Neuroblastoma Cells with Long Telomeres

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Fully automated viability and toxicity screening—A reliable all‐in‐one attempt

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Illuminating Dark Chemical Matter Using the Cell Painting Assay

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Small-Molecule Inhibition of CBX4/7 Hypersensitises Homologous Recombination-Impaired Cancer to Radiation by Compromising CtIP-Mediated DNA End Resection

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A comparative analysis of paxillin and Hic-5 proximity interactomes

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Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8

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Doxorubicin induces deglycosylation of cancer cell-intrinsic PD-1 by NGLY1

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Applying 3D correlative structured illumination microscopy and X-ray tomography to characterise herpes simplex virus-1 morphogenesis

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mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway

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TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks

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Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism

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Centriolar satellites are sites of translation of centrosomal and ciliary proteins

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Ferroptosis induces membrane blebbing in placental trophoblasts

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Intracellular delivery of oncolytic viruses with engineered Salmonella causes viral replication and cell death

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The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ

1
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  DOI: 10.1016/j.ebiom.2024.105124
  
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A dynamin superfamily-like pseudoenzyme coordinates with MICOS to promote cristae architecture

1
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Correcting 4sU induced quantification bias in nucleotide conversion RNA-seq data

1
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Unprocessed genomic uracil as a source of DNA replication stress in cancer cells

1
1. scibot 30 Apr 2024
  
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TM7SF3 controls TEAD1 splicing to prevent MASH-induced liver fibrosis

1
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miR-217 regulates normal and tumor cell fate following induction of Endoplasmic Reticulum Stress

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  DOI: 10.1158/1541-7786.MCR-23-0676
  
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RAD51 restricts DNA over-replication from re-activated origins

1
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DNA-PK and ATM drive phosphorylation signatures that antagonistically regulate cytokine responses to herpesvirus infection or DNA damage

1
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The BLM-TOP3A-RMI1-RMI2 proximity map reveals that RAD54L2 suppresses sister chromatid exchanges

1
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  DOI: 10.1101/2024.04.07.588476
  
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Time-series reconstruction of the molecular architecture of human centriole assembly

1
1. scibot 11 Apr 2024
  
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FEBS Press

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  DOI: 10.1002/1878-0261.13645
  
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RAD51 separation of function mutation disables replication fork maintenance but preserves DSB repair

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TDP-43 deficiency in Suprachiasmatic Nucleus perturbs rhythmicity of neuroactivity in Prefrontal Cortex

2
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BLM helicase unwinds lagging strand substrates to assemble the ALT telomere damage response

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Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum

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  DOI: 10.1016/j.devcel.2024.03.014
  
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Temporal dynamics and stoichiometry in human Notch signaling from Notch synaptic complex formation to nuclear entry of the Notch intracellular domain

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FAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis

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Stabilization of F-actin by Salmonella effector SipA resembles the structural effects of inorganic phosphate and phalloidin

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Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity

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Lysosomal damage sensing and lysophagy initiation by SPG20-ITCH

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The immediate-early protein 1 of human herpesvirus 6B interacts with NBS1 and inhibits ATM signaling

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  DOI: 10.1038/s44319-023-00035-z
  
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RAD51 restricts DNA over-replication from re-activated origins

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RAD51 restricts DNA over-replication from re-activated origins

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HDAC5 enhances IRF3 activation and is targeted for degradation by protein C6 from orthopoxviruses including Monkeypox virus and Variola virus

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Genome-scale requirements for dynein-based transport revealed by a high-content arrayed CRISPR screen

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CDK-independent role of D-type cyclins in regulating DNA mismatch repair

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Securin acetylation prevents precocious separase activation and premature sister chromatid separation

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  DOI: 10.1016/j.cub.2024.02.038
  
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Non-canonical isoforms of the mRNA polyadenylation factor WDR33 regulate STING-mediated immune responses

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A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis

1
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Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection

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53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication

1
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  RRID:CVCL_0042
  
  DOI: 10.1101/2023.09.27.559698
  
  Resource: (CLS Cat# 300364/p489_U-2_OS, RRID:CVCL_0042)
  
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52.53.155.43/9b07aa3872d935df1f2ff4d73fc96f76996bcf22/2023.09.27.559698v1.full-html.html
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Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting

1
1. scibot 21 Feb 2024
  
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  RRID: CVCL_0042
  
  DOI: 10.1016/j.molcel.2024.01.022
  
  Resource: (CLS Cat# 300364/p489_U-2_OS, RRID:CVCL_0042)
  
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PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma

1
1. scibot 21 Feb 2024
  
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  CVCL_0042
  
  DOI: 10.1038/s41467-024-45760-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10873513/
onlinelibrary.wiley.com onlinelibrary.wiley.com

Deposition of onco-histone H3.3-G34W leads to DNA repair deficiency and activates cGAS/STING-mediated immune responses

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1. scibot 18 Feb 2024
  
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  RRID:CVCL_0042
  
  DOI: 10.1002/ijc.34883
  
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onlinelibrary.wiley.com/doi/full/10.1002/ijc.34883
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Circadian period is compensated for repressor protein turnover rates in single cells

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1. scibot 15 Feb 2024
  
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  RRID:CVCL_0042
  
  DOI: 10.1101/2024.02.06.579141
  
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biorxiv.org/content/10.1101/2024.02.06.579141v1
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Human YKT6 forms priming complex with STX17 and SNAP29 to facilitate autophagosome-lysosome fusion

2
1. scibot 13 Feb 2024
  
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  HTB-96, ATCC
  
  DOI: 10.1016/j.celrep.2024.113760
  
  Resource: (CLS Cat# 300364/p489_U-2_OS, RRID:CVCL_0042)
  
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2. scibot 13 Feb 2024
  
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  ATCCHTB-96
  
  DOI: 10.1016/j.celrep.2024.113760
  
  Resource: (CLS Cat# 300364/p489_U-2_OS, RRID:CVCL_0042)
  
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PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression

1
1. scibot 06 Feb 2024
  
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  ATCCHTB-96
  
  DOI: 10.1016/j.cmet.2024.01.006
  
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qTAG: An adaptable CRISPR-based endogenous tagging protocol using optimized repair cassettes.

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1. scibot 04 Feb 2024
  
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  RRID:CVCL_0042
  
  DOI: 10.1101/2023.11.01.565029
  
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biorxiv.org/content/10.1101/2023.11.01.565029v2
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Dual roles of CCDC102A in governing centrosome duplication and cohesion

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1. scibot 02 Feb 2024
  
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  RRID:CVCL_0042
  
  DOI: 10.1016/j.celrep.2024.113696
  
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CAG repeat expansions create splicing acceptor sites and produce aberrant repeat-containing RNAs

1
1. scibot 02 Feb 2024
  
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  RRID:CVCL_0042
  
  DOI: 10.1016/j.molcel.2024.01.006
  
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SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion

1
1. scibot 02 Feb 2024
  
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  RRID:CVCL_0042
  
  DOI: 10.1016/j.cell.2024.01.008
  
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Jan 2024
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MCAK Inhibitors Induce Aneuploidy in Triple-Negative Breast Cancer Models

1
1. scibot 25 Jan 2024
  
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  CVCL_0042
  
  DOI: 10.3390/cancers15133309
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10340532/
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CCDC85A is regulated by miR-224-3p and augments cancer cell resistance to endoplasmic reticulum stress

1
1. scibot 25 Jan 2024
  
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  CVCL_0042
  
  DOI: 10.3389/fonc.2023.1196546
  
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SUMO-activated target traps (SATTs) enable the identification of a comprehensive E3-specific SUMO proteome

1
1. scibot 18 Jan 2024
  
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  RRID:CVCL_0042
  
  DOI: 10.1126/sciadv.adh2073
  
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Distinct modes of telomere synthesis and extension contribute to Alternative Lengthening of Telomeres

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1. scibot 14 Jan 2024
  
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  RRID:CVCL_0042
  
  DOI: 10.1016/j.isci.2023.108655
  
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p300 is an obligate integrator of combinatorial transcription factor inputs

1
1. scibot 11 Jan 2024
  
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  RRID:CVCL_0042
  
  DOI: 10.1016/j.molcel.2023.12.004
  
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GRB2 is a BECN1 interacting protein that regulates autophagy.

1
1. scibot 11 Jan 2024
  
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  CVCL_0042
  
  DOI: 10.1038/s41419-023-06387-7
  
  Resource: (CLS Cat# 300364/p489_U-2_OS, RRID:CVCL_0042)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10770341/
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Identification of TNFRSF21 as an inhibitory factor of osteosarcoma based on a necroptosis-related prognostic gene signature and molecular experiments

1
1. scibot 10 Jan 2024
  
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  RRID:CVCL_0042
  
  DOI: 10.1186/s12935-023-03198-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10770912/
Dec 2023
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Bi-allelic variants in CEP295 cause Seckel-like syndrome presenting with primary microcephaly, developmental delay, intellectual disability, short stature, craniofacial and digital abnormalities

1
1. scibot 29 Dec 2023
  
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  RRID:CVCL_0042
  
  DOI: 10.1016/j.ebiom.2023.104940
  
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