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382 Matching Annotations

Mar 2024
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

Combining VPS34 inhibitors with STING agonists enhances type I interferon signaling and anti-tumor efficacy

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1. scibot 28 Mar 2024
  
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  DOI: 10.1002/1878-0261.13619
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13619
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De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis

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1. scibot 19 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113936
  
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sciencedirect.com/science/article/pii/S221112472400264X
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Low expression of lysosome-related genes KCNE1, NPC2, and SFTPD promote cancer cell proliferation and tumor associated M2 macrophage polarization in lung adenocarcinoma

1
1. scibot 05 Mar 2024
  
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  DOI: 10.1016/j.heliyon.2024.e27575
  
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sciencedirect.com/science/article/pii/S2405844024036065
Feb 2024
52.53.155.43 52.53.155.43

d4-html.html

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  DOI: 10.1158/1541-7786.mcr-23-0109
  
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52.53.155.43/f092aa63506937030df3074397696edbfe46ccc6/d4-html.html
52.53.155.43 52.53.155.43

delet 4-html.html

2
1. scibot 29 Feb 2024
  
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  DOI: 10.1158/1078-0432.ccr-23-1872
  
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  DOI: 10.1158/1078-0432.ccr-23-1872
  
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52.53.155.43/000a1f53d3edcfbfcb18b2f1b43043d283dcfb60/delet 4-html.html
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Diverse temporal and spatial mechanisms work, partially through Stanniocalcin-1, V-ATPase and senescence, to activate the extracellular ATP-mediated drug resistance in human cancer cells

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1. scibot 22 Feb 2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10876858/
www.biorxiv.org www.biorxiv.org

A common druggable signature of oncogenic CMYC, mutant KRAS and mutant p53 reveals functional redundancy and competition of the oncogenes in cancer

1
1. scibot 15 Feb 2024
  
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  DOI: 10.1101/2023.12.20.572548
  
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biorxiv.org/content/10.1101/2023.12.20.572548v1
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Tumoral and stromal hMENA isoforms impact tertiary lymphoid structure localization in lung cancer and predict immune checkpoint blockade response in patients with cancer

1
1. scibot 14 Feb 2024
  
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sciencedirect.com/science/article/pii/S2352396424000380
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HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

3
1. scibot 09 Feb 2024
  
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  DOI: 10.1101/2023.12.05.570182
  
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2. scibot 09 Feb 2024
  
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  DOI: 10.1101/2023.12.05.570182
  
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  DOI: 10.1101/2023.12.05.570182
  
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biorxiv.org/content/10.1101/2023.12.05.570182v1
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Targeting TOP2B as a vulnerability in aging and aging-related diseases

1
1. scibot 07 Feb 2024
  
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  DOI: 10.1016/j.bbadis.2024.167044
  
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sciencedirect.com/science/article/pii/S0925443924000292
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PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression

1
1. scibot 06 Feb 2024
  
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  ATCCCRL-5803
  
  DOI: 10.1016/j.cmet.2024.01.006
  
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sciencedirect.com/science/article/pii/S1550413124000056
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men

1
1. scibot 03 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.108858
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10830871/
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SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway

1
1. scibot 02 Feb 2024
  
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  DOI: 10.1016/j.canlet.2024.216667
  
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sciencedirect.com/science/article/pii/S0304383524000612
Jan 2024
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FBXL16 promotes cell growth and drug resistance in lung adenocarcinomas with KRAS mutation by stabilizing IRS1 and upregulating IRS1/AKT signaling

1
1. scibot 25 Jan 2024
  
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  RRID:CVCL_0060
  
  DOI: 10.1002/1878-0261.13554
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13554
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Overexpression of MRPL19 in predicting poor prognosis and promoting the development of lung adenocarcinoma

1
1. scibot 25 Jan 2024
  
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  CVCL_0060
  
  DOI: 10.21037/tlcr-23-306
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10413030/
www.cell.com www.cell.com

p53-responsive CMBL reprograms glucose metabolism and suppresses cancer development by destabilizing phosphofructokinase PFKP

1
1. scibot 25 Jan 2024
  
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  CVCL_0060
  
  DOI: 10.1016/j.celrep.2023.113426
  
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cell.com/cell-reports/abstract/S2211-1247(23)01438-9
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The pleiotropic enhancer enh9 promotes cell proliferation and migration in non-small cell lung cancer via ERMP1 and PD-L1

1
1. scibot 05 Jan 2024
  
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  DOI: 10.1016/j.bbadis.2023.167015
  
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sciencedirect.com/science/article/pii/S0925443923003812
Dec 2023
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A helicase-independent role of DHX15 promotes MYC stability and acute leukemia cell survival

1
1. scibot 21 Dec 2023
  
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  ATCCCat# CRL-5803
  
  DOI: 10.1016/j.isci.2023.108571
  
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sciencedirect.com/science/article/pii/S2589004223026482
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Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability

1
1. scibot 02 Dec 2023
  
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  RRID:CVCL_0060
  
  DOI: 10.1016/j.celrep.2023.113503
  
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sciencedirect.com/science/article/pii/S2211124723015152
Nov 2023
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Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy

1
1. scibot 17 Nov 2023
  
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  RRID:CVCL_0060
  
  DOI: 10.1016/j.chembiol.2023.10.010
  
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sciencedirect.com/science/article/pii/S2451945623003719
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Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment

1
1. scibot 12 Nov 2023
  
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  RRID: CVCL_0060
  
  DOI: 10.1002/ijc.34783
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.34783
52.53.155.43 52.53.155.43

British J Pharmacology - 2023 - Chen - Identification of arnicolide C as a novel chemosensitizer to suppress mTOR E2F1-html.html

1
1. scibot 10 Nov 2023
  
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  RRID:CVCL_0060
  
  DOI: 10.1111/bph.16281
  
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52.53.155.43/fa9809949a94f3d698a02ed4d13d532c010d3e91/British J Pharmacology - 2023 - Chen - Identification of arnicolide C as a novel chemosensitizer to suppress mTOR E2F1-html.html
www.sciencedirect.com www.sciencedirect.com

mTORC1 promotes cell growth via m6A-dependent mRNA degradation

1
1. scibot 04 Nov 2023
  
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  RRID:CVCL_0060
  
  DOI: 10.1016/j.molcel.2021.03.010
  
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  RRIDCUR:Validated RRID:CVCL_0060
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sciencedirect.com/science/article/pii/S1097276521001787
Sep 2023
link.springer.com link.springer.com

A dual role for ERK-1/2 in the regulation of plasmin activity and cell migration in metastatic NSCLC-H1299 cells

1
1. scibot 16 Sep 2023
  
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  RRID:CVCL_0060
  
  DOI: 10.1007/s00204-023-03600-6
  
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link.springer.com/article/10.1007/s00204-023-03600-6
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 14 Sep 2023
  
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  RRID:CVCL_0060
  
  DOI: 10.1111/bph.16165
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16165
Aug 2023
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

Canagliflozin mediates tumor suppression alone and in combination with radiotherapy in non-small cell lung cancer (NSCLC) through inhibition of HIF-1α

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1. scibot 29 Aug 2023
  
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  RRID:CVCL_0060
  
  DOI: 10.1002/1878-0261.13508
  
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febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13508
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FEBS Press

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1. scibot 29 Aug 2023
  
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  RRID:CVCL_0060
  
  DOI: 10.1111/febs.16933
  
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febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.16933
Jul 2023
www.nature.com www.nature.com

E3 ligase MG53 suppresses tumor growth by degrading cyclin D1

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1. scibot 08 Jul 2023
  
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  RRID: CVCL_0060
  
  DOI: 10.1038/s41392-023-01458-9
  
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nature.com/articles/s41392-023-01458-9
Jun 2023
52.53.155.43 52.53.155.43

1-s2.0-S1043661823001743-main-html.html

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1. scibot 23 Jun 2023
  
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  RRID:CVCL_0060
  
  DOI: 10.1016/j.phrs.2023.106818
  
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52.53.155.43/e232ebeba51bf57a731f1eed5bf04c2635b8d998/1-s2.0-S1043661823001743-main-html.html
May 2023
52.53.155.43 52.53.155.43

Global identification of direct SWI/SNF targets reveals compensation by EP400

1
1. scibot 27 May 2023
  
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  CRL-5803
  
  DOI: 10.1101/2023.03.07.531379
  
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52.53.155.43/1f9bfe96276133d800deede23a60dc1d07ed8bc3/2023.03.07.531379v1.full-html.html
52.53.155.43 52.53.155.43

FEBS Press

1
1. scibot 20 May 2023
  
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  RRID:CVCL_0060
  
  DOI: 10.1002/1878-0261.13448
  
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52.53.155.43/55175f335d9d63eca4c96b1d663be208d4b843b1/Molecular Oncology - 2023 - Koob - MND1 enables homologous recombination in somatic cells primarily outside the context of-html.html
aacrjournals.org aacrjournals.org

Decoding the lncRNAome across diverse cellular stresses reveals core p53-effector pan-cancer suppressive lncRNAs

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1. scibot 12 May 2023
  
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  RRID:CVCL_0060
  
  DOI: 10.1158/2767-9764.CRC-22-0473
  
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aacrjournals.org/cancerrescommun/article/3/5/842/726358/Decoding-the-lncRNAome-Across-Diverse-Cellular
Apr 2023
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RAB27B Drives a Cancer Stem Cell Phenotype in NSCLC Cells Through Enhanced Extracellular Vesicle Secretion

1
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IKZF4 acts as a novel tumor suppressor in non–small cell lung cancer by suppressing Notch signaling pathway

1
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Intronic Cis-Element DR8 in hTERT Is Bound by Splicing Factor SF3B4 and Regulates hTERT Splicing in Non-Small Cell Lung Cancer

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PLCG2 can exist in eccDNA and contribute to the metastasis of non-small cell lung cancer by regulating mitochondrial respiration

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Mar 2023
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Comprehensive Explorations of CCL28 in Lung Adenocarcinoma Immunotherapy and Experimental Validation

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S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) inhibits lung cancer tumorigenesis by regulating cell plasticity

1
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Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells

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PhAc-ALGP-Dox, a Novel Anticancer Prodrug with Targeted Activation and Improved Therapeutic Index

1
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EGFR-phosphorylated GDH1 harmonizes with RSK2 to drive CREB activation and tumor metastasis in EGFR-activated lung cancer

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Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction

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Hematopoietic transcription factor GFI1 promotes anchorage independence by sustaining ERK activity in cancer cells

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The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells

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Analyses of rare predisposing variants of lung cancer in 6,004 whole genomes in Chinese

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Lung fibrogenic microenvironment in mouse reconstitutes human alveolar structure and lung tumor

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149551.1-20220712091612-covered-e0fd13ba177f913fd3156f593ead4cfd-html.html

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52.53.155.43 52.53.155.43

mcr-21-0058-html.html

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Developmental pathways are epigenetically reprogrammed during lung cancer brain metastasis

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aacrjournals.org/cancerres/article/82/15/2692/707331/Developmental-Pathways-Are-Epigenetically
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Cancer-associated fibroblasts in nonsmall cell lung cancer: From molecular mechanisms to clinical implications

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onlinelibrary.wiley.com/doi/10.1002/ijc.34127
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BTApep-TAT peptide inhibits ADP-ribosylation of BORIS to induce DNA damage in cancer

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  DOI: 10.1186/s12943-022-01621-w
  
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molecular-cancer.biomedcentral.com/articles/10.1186/s12943-022-01621-w
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A small-molecule Skp1 inhibitor elicits cell death by p53-dependent mechanism

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Poroptosis: a form of cell death depending on plasma membrane nanopores formation

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MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression

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SETD4-mediated KU70 methylation suppresses apoptosis

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Systematic discovery of mutation-directed neo-protein-protein interactions in cancer

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cell.com/cell/fulltext/S0092-8674(22)00461-5
Apr 2022
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SARS-CoV-2 variants C.1.2 and B.1.621 (Mu) partially evade neutralization by antibodies elicited upon infection or vaccination

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Purification and cryo-EM structure determination of VCP/p97 dodecamers from mammalian and bacterial cells

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Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells

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Repurposing antiparasitic antimonials to noncovalently rescue temperature-sensitive p53 mutations

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Nuclear microRNAs release paused Pol II via the DDX21-CDK9 complex

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Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks

1
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Cross-species tropism and antigenic landscapes of circulating SARS-CoV-2 variants

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Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases

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A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer

1
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Micropeptide PACMP inhibition elicits synthetic lethal effects by decreasing CtIP and poly(ADP-ribosyl)ation

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Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity

1
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LncRNA FENDRR-mediated tumor suppression and tumor-immune microenvironment changes in non-small cell lung cancer

1
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Optogenetic EB1 inactivation shortens metaphase spindles by disrupting cortical force-producing interactions with astral microtubules

2
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  ATCCCRL-5803
  
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MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells

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Senescence marker protein 30 inhibits tumor growth by reducing HDAC4 expression in non-small cell lung cancer

1
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Nedd9 restrains autophagy to limit growth of early stage non-small cell lung cancer

1
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Protein modifications throughout the lung cancer proteome unravel the cancer-specific regulation of glycolysis

1
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Halofuginone Sensitizes Lung Cancer Organoids to Cisplatin via Suppressing PI3K/AKT and MAPK Signaling Pathways

1
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SAGE1: a Potential Target Antigen for Lung Cancer T-Cell Immunotherapy

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HNRNPA2B1 as a trigger of RNA switch modulates the miRNA-mediated regulation of CDK6

1
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FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma

1
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RNF8-mediated regulation of Akt promotes lung cancer cell survival and resistance to DNA damage

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EGFR transcriptionally upregulates UTX via STAT3 in non-small cell lung cancer

1
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Quantitative differences between cyclin-dependent kinases underlie the unique functions of CDK1 in human cells

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Oncogene-dependent sloppiness in mRNA translation

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Multiplatform discovery and regulatory function analysis of structural variations in non-small cell lung carcinoma

1
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Untitled document

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Untitled document

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Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy

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Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer

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Decoupling global biases and local interactions between cell biological variables

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RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer

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Untitled document

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Three optimized assays for the evaluation of compounds that can rescue p53 mutants

1
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miR-762 activation confers acquired resistance to gefitinib in non-small cell lung cancer

1
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EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex

1
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Membrane Tension Orchestrates Rear Retraction in Matrix-Directed Cell Migration

1
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Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers

1
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Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy

1
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  H1299
  
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Nuclear PGK1 Alleviates ADP-Dependent Inhibition of CDC7 to Promote DNA Replication

1
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A small molecule drug promoting miRNA processing induces alternative splicing of MdmX transcript and rescues p53 activity in human cancer cells overexpressing MdmX protein

1
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  H1299
  
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Development of potent dimeric inhibitors of GAS41 YEATS domain

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Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell

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A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma

1
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  DOI: 10.7554/eLife.65234
  
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RAL GTPases mediate EGFR-driven intestinal stem cell proliferation and tumourigenesis

1
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  DOI: 10.7554/eLife.63807
  
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MicroRNA-320a-containing exosomes from human umbilical cord mesenchymal stem cells curtail proliferation and metastasis in lung cancer by binding to SOX4

1
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tandfonline.com/doi/abs/10.1080/10799893.2021.1918166
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PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR

1
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3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis

1
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Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth

1
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Non-canonical Glutamate-Cysteine Ligase Activity Protects against Ferroptosis

1
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Glutamine deficiency promotes stemness and chemoresistance in tumor cells through DRP1-induced mitochondrial fragmentation

1
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Identification of Small-Molecule Activators of the Ubiquitin Ligase E6AP/UBE3A and Angelman Syndrome-Derived E6AP/UBE3A Variants

1
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A circular network of coregulated sphingolipids dictates lung cancer growth and progression

1
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Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis

1
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A selective p53 activator and anticancer agent to improve colorectal cancer therapy

1
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mTORC1 promotes cell growth via m6A-dependent mRNA degradation

1
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Adhesion strength and contractility enable metastatic cells to become adurotactic

1
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  ATCC CRL-5803
  
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Characterization of SALL2 Gene Isoforms and Targets Across Cell Types Reveals Highly Conserved Networks

1
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  DOI: 10.3389/fgene.2021.613808
  
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academic.oup.com academic.oup.com

Circular RNA hsa_circ_0102231 sponges miR-145 to promote non-small cell lung cancer cell proliferation by up-regulating the expression of RBBP4

1
1. scibot 03 Mar 2021
  
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  NCI-H1299
  
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academic.oup.com/jb/article/169/1/65/5934512
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MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity

1
1. scibot 03 Mar 2021
  
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  CRL-5803
  
  DOI: 10.1016/j.celrep.2021.108808
  
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Transketolase regulates sensitivity to APR-246 in p53-null cells independently of oxidative stress modulation

1
1. scibot 02 Mar 2021
  
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  DOI: 10.1038/s41598-021-83979-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7904805/
Feb 2021
cancerres.aacrjournals.org cancerres.aacrjournals.org

3D Functional Genomics Screens Identify CREBBP as a Targetable Driver in Aggressive Triple-Negative Breast Cancer

1
1. scibot 24 Feb 2021
  
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  DOI: 10.1158/0008-5472.CAN-20-1822
  
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cancerres.aacrjournals.org/content/81/4/847
Jan 2021
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CLINICALLY RELEVANT CELL CULTURE MODELS AND THEIR SIGNIFICANCE IN ISOLATION, PATHOGENESIS, VACCINE DEVELOPMENT, REPURPOSING AND SCREENING OF NEW DRUGS FOR SARS-COV-2: A SYSTEMATIC REVIEW

1
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  DOI: 10.1016/j.tice.2021.101497
  
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Proteome-wide identification of NEDD8 modification sites reveals distinct proteomes for canonical and atypical NEDDylation

1
1. scibot 20 Jan 2021
  
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  H1299
  
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A Potent and Selective Dual Inhibitor of AXL and MERTK Possesses Both Immunomodulatory and Tumor-Targeted Activity

1
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  DOI: 10.3389/fonc.2020.598477
  
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Increased demand for NAD+ relative to ATP drives aerobic glycolysis

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  DOI: 10.1016/j.molcel.2020.12.012
  
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Oct 2020
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The mTORC1/S6K/PDCD4/eIF4A Axis Determines Outcome of Mitotic Arrest

1
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  H1299
  
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sciencedirect.com/science/article/pii/S2211124720312195
Sep 2020
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HSPA2 Chaperone Contributes to the Maintenance of Epithelial Phenotype of Human Bronchial Epithelial Cells but Has Non-Essential Role in Supporting Malignant Features of Non-Small Cell Lung Carcinoma, MCF7, and HeLa Cancer Cells

1
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  NCI-H1299
  
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BPS Publications

1
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  DOI: 10.1111/bph.14793
  
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FBXW7 Confers Radiation Survival by Targeting p53 for Degradation

1
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SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

1
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cancerres.aacrjournals.org cancerres.aacrjournals.org

Oxygen-enhanced optoacoustic tomography reveals the effectiveness of targeting heme and oxidative phosphorylation at normalizing tumor vascular oxygenation

1
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  DOI: 10.1158/0008-5472.CAN-19-3247
  
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Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma

1
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  DOI: 10.7554/eLife.53367
  
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The Negative Cross-Talk between SAG/RBX2/ROC2 and APC/C E3 Ligases in Regulation of Cell Cycle Progression and Drug Resistance

1
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  H1299
  
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The effects of 20-kDa human placental GH in male and female GH deficient mice: an improved human GH?

1
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  DOI: 10.1210/endocr/bqaa097
  
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academic.oup.com/endo/article/161/8/bqaa097/5859553
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Chromosome 3q26 Gain Is an Early Event Driving Coordinated Overexpression of the PRKCI, SOX2, and ECT2 Oncogenes in Lung Squamous Cell Carcinoma

1
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Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay

1
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  DOI: 10.1016/j.molcel.2019.06.001
  
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Various Anti-HSPA2 Antibodies Yield Different Results in Studies on Cancer-Related Functions of Heat Shock Protein A2

1
1. scibot 03 Sep 2020
  
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  NCI-H1299
  
  DOI: 10.3390/ijms21124296
  
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Combination of CHEK1/2 inhibition and ionizing radiation results in abscopal tumor response through increased micronuclei formation

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  DOI: 10.1038/s41388-020-1300-x
  
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The transcription factor FLI1 promotes cancer progression by affecting cell cycle regulation

1
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  DOI: 10.1002/ijc.32831
  
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Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer

1
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  DOI: 10.7554/eLife.45572
  
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GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway

1
1. scibot 13 Jan 2020
  
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Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation

1
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Activation of Oxidative Stress Response in Cancer Generates a Druggable Dependency on Exogenous Non-essential Amino Acids

1
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  DOI: 10.1016/j.cmet.2019.11.012
  
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BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis

1
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VISAGE Reveals a Targetable Mitotic Spindle Vulnerability in Cancer Cells

1
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γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A

1
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SFRPs Are Biphasic Modulators of Wnt-Signaling-Elicited Cancer Stem Cell Properties beyond Extracellular Control

1
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Radioresistance of KRAS/TP53‐Mutated Lung Cancer can be overcome by Radiation Dose Escalation or EGFR Tyrosine Kinase Inhibition In Vivo

1
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  DOI: 10.1002/ijc.32598
  
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cancerres.aacrjournals.org cancerres.aacrjournals.org

Elevated Heme Synthesis and Uptake Underpin Intensified Oxidative Metabolism and Tumorigenic Functions in Non–Small Cell Lung Cancer Cells

1
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  DOI: 10.1158/0008-5472.CAN-18-2156
  
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cancerres.aacrjournals.org/content/79/10/2511
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Untitled document

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  DOI: 10.1016/j.celrep.2019.02.052
  
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Untitled document

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  DOI: 10.1016/j.celrep.2019.01.043
  
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Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion

1
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  DOI: 10.1016/j.cmet.2019.01.020
  
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MDM2 Integrates Cellular Respiration and Apoptotic Signaling through NDUFS1 and the Mitochondrial Network

1
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  DOI: 10.1016/j.molcel.2019.02.012
  
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sciencedirect.com/science/article/pii/S1097276519301029
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elifesciences.org elifesciences.org

Palmitoylated SCP1 is targeted to the plasma membrane and negatively regulates angiogenesis

1
1. scibot 05 Apr 2019
  
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  CVCL-0060
  
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elifesciences.org/content/6/e22058
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Untitled document

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1. scibot 04 Apr 2019
  
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elifesciences.org/articles/22323
Nov 2018
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Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair

1
1. scibot 05 Nov 2018
  
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  CRL-5803
  
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Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting

1
1. scibot 05 Nov 2018
  
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  CRL-5803
  
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Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion

1
1. scibot 05 Nov 2018
  
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  CRL-5803
  
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Dependence on the Pyrimidine Biosynthetic Enzyme DHODH Is a Synthetic Lethal Vulnerability in Mutant KRAS-Driven Cancers

1
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  CRL-5803
  
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MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation

1
1. scibot 05 Nov 2018
  
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  CRL-5803
  
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A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation

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UBE2M Is a Stress-Inducible Dual E2 for Neddylation and Ubiquitylation that Promotes Targeted Degradation of UBE2F

1
1. scibot 05 Nov 2018
  
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  CRL-5803
  
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iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding

1
1. scibot 05 Nov 2018
  
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  CRL-5803
  
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The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells

1
1. scibot 05 Nov 2018
  
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CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness

1
1. scibot 05 Nov 2018
  
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  CRL-5803
  
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elifesciences.org elifesciences.org

SPIN1 promotes tumorigenesis by blocking the uL18 (universal large ribosomal subunit protein 18)-MDM2-p53 pathway in human cancer

1
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  RRID:CVCL_0060
  
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elifesciences.org/articles/31275
europepmc.org europepmc.org

A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants

1
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europepmc.org/articles/PMC5655547/
Nov 2017
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Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover

1
1. scibot 08 Nov 2017
  
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  CRL-5803
  
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Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition

1
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  RRID:CVCL_0060
  
  Curator: @kaitlinsung
  
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elifesciences.org/articles/27713
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Ccdc3: A New P63 Target Involved in Regulation Of Liver Lipid Metabolism

1
1. scibot 08 Nov 2017
  
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nature.com/articles/s41598-017-09228-8
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Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication

1
1. scibot 08 Nov 2017
  
  in Public
  
  CRL-5803
  
  Curator: @Jmenke
  
  Resource used:
  
  (ATCC Cat# CRL-5803, RRID:CVCL_0060)
  
  SciCrunch record: RRID:CVCL_0060
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0060 RRIDCUR:Missing
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RRID:CVCL_0060

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1097276517301727
www.sciencedirect.com www.sciencedirect.com

Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy

1
1. scibot 08 Nov 2017
  
  in Public
  
  CRL-5803
  
  Curator: @Zeljana_Babic
  
  Resource used:
  
  (ATCC Cat# CRL-5803, RRID:CVCL_0060)
  
  SciCrunch record: RRID:CVCL_0060
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0060 RRIDCUR:Missing
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RRID:CVCL_0060

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1097276517303118
elifesciences.org elifesciences.org

Decoupling global biases and local interactions between cell biological variables

1
1. scibot 08 Nov 2017
  
  in Public
  
  CVCL_0060
  
  Curator: @kaitlinsung
  
  Resource used:
  
  (ATCC Cat# CRL-5803, RRID:CVCL_0060)
  
  SciCrunch record: RRID:CVCL_0060
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0060 RRIDCUR:Validated
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RRID:CVCL_0060

RRIDCUR:Validated

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scibot

URL

elifesciences.org/content/6/e22323
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MK-8776, a novel chk1 kinase inhibitor, radiosensitizes p53-defective human tumor cells

1
1. scibot 08 Nov 2017
  
  in Public
  
  CVCL_0060
  
  Curator: @gabimpine
  
  Resource used:
  
  (ATCC Cat# CRL-5803, RRID:CVCL_0060)
  
  SciCrunch record: RRID:CVCL_0060
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0060 RRIDCUR:Validated
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RRID:CVCL_0060

RRIDCUR:Validated

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5342109/
www.sciencedirect.com www.sciencedirect.com

O2⋅− and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate

1
1. scibot 08 Nov 2017
  
  in Public
  
  CVCL_0060
  
  Curator: @kaitlinsung
  
  Resource used:
  
  (ATCC Cat# CRL-5803, RRID:CVCL_0060)
  
  SciCrunch record: RRID:CVCL_0060
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0060 RRIDCUR:Validated
Visit annotations in context

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RRID:CVCL_0060

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S1535610817300624
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions

2
1. scibot 08 Nov 2017
  
  in Public
  
  RRID: CVCL_0060
  
  Curator: @kaitlinsung
  
  Resource used:
  
  (ATCC Cat# CRL-5803, RRID:CVCL_0060)
  
  SciCrunch record: RRID:CVCL_0060
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0060 RRIDCUR:Missing
2. scibot 08 Nov 2017
  
  in Public
  
  CVCL_0060
  
  Resource used:
  
  (ATCC Cat# CRL-5803, RRID:CVCL_0060)
  
  SciCrunch record: RRID:CVCL_0060
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0060
Visit annotations in context

Tags

RRID:CVCL_0060

RRIDCUR:Missing

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC5092050/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inactivation of oncogenic cAMP-specific phosphodiesterase 4D by miR-139-5p in response to p53 activation

1
1. scibot 08 Nov 2017
  
  in Public
  
  CVCL_0060
  
  Curator: @gabimpine
  
  Resource used:
  
  (ATCC Cat# CRL-5803, RRID:CVCL_0060)
  
  SciCrunch record: RRID:CVCL_0060
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0060 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:CVCL_0060

RRIDCUR:Validated

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC4959878/

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