Hypothesis

226 Matching Annotations

Sep 2020
link.springer.com link.springer.com

Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy

1
1. scibot 03 Sep 2020
  
  in Public
  
  RRID:CVCL_0248
  
  DOI: 10.1186/s40170-019-0202-2
  
  Resource: (JCRB Cat# JCRB9094, RRID:CVCL_0248)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0248
  
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  RRID:CVCL_0248
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RRID:CVCL_0248

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scibot

URL

link.springer.com/article/10.1186/s40170-019-0202-2
www.sciencedirect.com www.sciencedirect.com

Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation

1
1. scibot 03 Sep 2020
  
  in Public
  
  Human: DLD1
  
  DOI: 10.1016/j.celrep.2019.12.075
  
  Resource: (JCRB Cat# JCRB9094, RRID:CVCL_0248)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0248
  
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  RRID:CVCL_0248 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0248

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719317401
Jan 2020
currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com

Rapid Tagging of Human Proteins with Fluorescent Reporters by Genome Engineering using Double‐Stranded DNA Donors

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0248
  
  DOI: 10.1002/cpmb.102
  
  Resource: (JCRB Cat# JCRB9094, RRID:CVCL_0248)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0248
  
  What is this?
  
  RRID:CVCL_0248 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0248

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scibot

URL

currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cpmb.102
www.mdpi.com www.mdpi.com

N6-Isopentenyladenosine Inhibits Colorectal Cancer and Improves Sensitivity to 5-Fluorouracil-Targeting FBXW7 Tumor Suppressor

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0248
  
  DOI: 10.3390/cancers11101456
  
  Resource: (JCRB Cat# JCRB9094, RRID:CVCL_0248)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0248
  
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  RRID:CVCL_0248 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0248

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scibot

URL

mdpi.com/2072-6694/11/10/1456
www.sciencedirect.com www.sciencedirect.com

Centromere Dysfunction Compromises Mitotic Spindle Pole Integrity

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0248
  
  DOI: 10.1016/j.cub.2019.07.052
  
  Resource: (JCRB Cat# JCRB9094, RRID:CVCL_0248)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0248
  
  What is this?
  
  RRID:CVCL_0248 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0248

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scibot

URL

sciencedirect.com/science/article/pii/S0960982219309327
www.sciencedirect.com www.sciencedirect.com

Proteogenomic Network Analysis of Context-Specific KRAS Signaling in Mouse-to-Human Cross-Species Translation

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0248
  
  DOI: 10.1016/j.cels.2019.07.006
  
  Resource: (JCRB Cat# JCRB9094, RRID:CVCL_0248)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0248
  
  What is this?
  
  RRID:CVCL_0248 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0248

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scibot

URL

sciencedirect.com/science/article/pii/S2405471219302388
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0248
  
  DOI: 10.1016/j.chembiol.2018.11.013
  
  Resource: (JCRB Cat# JCRB9094, RRID:CVCL_0248)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0248
  
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  RRID:CVCL_0248 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0248

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URL

sciencedirect.com/science/article/pii/S2451945618304355
Apr 2019
elifesciences.org elifesciences.org

Palmitoylated SCP1 is targeted to the plasma membrane and negatively regulates angiogenesis

1
1. scibot 05 Apr 2019
  
  in Public
  
  CVCL-0248
  
  Curator: @Zeljana_Babic
  
  Resource used:
  
  (TKG Cat# TKG 0379, RRID:CVCL_0248)
  
  SciCrunch record: RRID:CVCL-0248
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0248 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0248

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scibot

URL

elifesciences.org/content/6/e22058
Nov 2018
www.sciencedirect.com www.sciencedirect.com

APC Inhibits Ligand-Independent Wnt Signaling by the Clathrin Endocytic Pathway

1
1. scibot 05 Nov 2018
  
  in Public
  
  CCL-221
  
  Curator: @Jmenke
  
  Resource used:
  
  (TKG Cat# TKG 0379, RRID:CVCL_0248)
  
  SciCrunch record: RRID:CVCL_0248
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0248 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0248

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scibot

URL

sciencedirect.com/science/article/pii/S1534580718301084
www.sciencedirect.com www.sciencedirect.com

Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures

1
1. scibot 05 Nov 2018
  
  in Public
  
  CCL-221
  
  Curator: @Jmenke
  
  Resource used:
  
  (TKG Cat# TKG 0379, RRID:CVCL_0248)
  
  SciCrunch record: RRID:CVCL_0248
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0248 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0248

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scibot

URL

sciencedirect.com/science/article/pii/S2451945618303301
www.sciencedirect.com www.sciencedirect.com

Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair

1
1. scibot 05 Nov 2018
  
  in Public
  
  CCL-221
  
  Curator: @Jmenke
  
  Resource used:
  
  (TKG Cat# TKG 0379, RRID:CVCL_0248)
  
  SciCrunch record: RRID:CVCL_0248
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0248 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0248

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scibot

URL

sciencedirect.com/science/article/pii/S0092867418311176
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Simultaneous use of erythropoietin and LFM‐A13 as a new therapeutic approach for colorectal cancer

2
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0248
  
  Resource used:
  
  (TKG Cat# TKG 0379, RRID:CVCL_0248)
  
  SciCrunch record: RRID:CVCL_0248
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0248
2. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0248
  
  Curator: @evieth
  
  Resource used:
  
  (TKG Cat# TKG 0379, RRID:CVCL_0248)
  
  SciCrunch record: RRID:CVCL_0248
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0248 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0248

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5811618/
www.sciencedirect.com www.sciencedirect.com

Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion

1
1. scibot 05 Nov 2018
  
  in Public
  
  ACC 278
  
  Curator: @Jmenke
  
  Resource used:
  
  (TKG Cat# TKG 0379, RRID:CVCL_0248)
  
  SciCrunch record: RRID:CVCL_0248
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0248 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0248

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scibot

URL

sciencedirect.com/science/article/pii/S153561081830309X
www.sciencedirect.com www.sciencedirect.com

Dependence on the Pyrimidine Biosynthetic Enzyme DHODH Is a Synthetic Lethal Vulnerability in Mutant KRAS-Driven Cancers

1
1. scibot 05 Nov 2018
  
  in Public
  
  CCL-221
  
  Curator: @Jmenke
  
  Resource used:
  
  (TKG Cat# TKG 0379, RRID:CVCL_0248)
  
  SciCrunch record: RRID:CVCL_0248
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0248 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0248

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scibot

URL

sciencedirect.com/science/article/pii/S2451945618301077
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0248
  
  Resource used:
  
  (TKG Cat# TKG 0379, RRID:CVCL_0248)
  
  SciCrunch record: RRID:CVCL_0248
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0248
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RRID:CVCL_0248

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6039175/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0248
  
  Curator: @evieth
  
  Resource used:
  
  (TKG Cat# TKG 0379, RRID:CVCL_0248)
  
  SciCrunch record: RRID:CVCL_0248
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0248 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0248

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5979332/
www.sciencedirect.com www.sciencedirect.com

Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0248
  
  Resource used:
  
  (TKG Cat# TKG 0379, RRID:CVCL_0248)
  
  SciCrunch record: RRID:CVCL_0248
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0248
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RRID:CVCL_0248

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scibot

URL

sciencedirect.com/science/article/pii/S0092867417312631
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Multivalent Small-Molecule Pan-RAS Inhibitors

1
1. scibot 08 Nov 2017
  
  in Public
  
  CCL-221
  
  Curator: @Jmenke
  
  Resource used:
  
  (TKG Cat# TKG 0379, RRID:CVCL_0248)
  
  SciCrunch record: RRID:CVCL_0248
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0248 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0248

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scibot

URL

sciencedirect.com/science/article/pii/S0092867417301848
www.sciencedirect.com www.sciencedirect.com

Cell Permeable Stapled Peptide Inhibitor of Wnt Signaling that Targets β-Catenin Protein-Protein Interactions

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID: CVCL_0248
  
  Curator: @Jmenke
  
  Resource used:
  
  (TKG Cat# TKG 0379, RRID:CVCL_0248)
  
  SciCrunch record: RRID:CVCL_0248
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0248
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RRID:CVCL_0248

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scibot

URL

sciencedirect.com/science/article/pii/S2451945617302271
www.sciencedirect.com www.sciencedirect.com

Lck/Hck/Fgr-Mediated Tyrosine Phosphorylation Negatively Regulates TBK1 to Restrain Innate Antiviral Responses

1
1. scibot 08 Nov 2017
  
  in Public
  
  DLD1ATCCCat#CCL-221
  
  Curator: @Jmenke
  
  Resource used:
  
  (TKG Cat# TKG 0379, RRID:CVCL_0248)
  
  SciCrunch record: RRID:CVCL_0248
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0248 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0248

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scibot

URL

sciencedirect.com/science/article/pii/S1931312817302032
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases

1
1. scibot 08 Nov 2017
  
  in Public
  
  CVCL_0248
  
  Curator: @gabimpine
  
  Resource used:
  
  (TKG Cat# TKG 0379, RRID:CVCL_0248)
  
  SciCrunch record: RRID:CVCL_0248
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0248
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RRID:CVCL_0248

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5224920/
onlinelibrary.wiley.com onlinelibrary.wiley.com

Loss of TET1 facilitates DLD1 colon cancer cell migration via H3K27me3‐mediated down‐regulation of E‐cadherin

1
1. scibot 08 Nov 2017
  
  in Public
  
  CVCL_0248
  
  Curator: @chewbeccax
  
  Resource used:
  
  (TKG Cat# TKG 0379, RRID:CVCL_0248)
  
  SciCrunch record: RRID:CVCL_0248
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0248 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0248

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scibot

URL

onlinelibrary.wiley.com/doi/10.1002/jcp.26012/full
www.sciencedirect.com www.sciencedirect.com

A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis

1
1. scibot 08 Nov 2017
  
  in Public
  
  CCL-221
  
  Curator: @gabimpine
  
  Resource used:
  
  (TKG Cat# TKG 0379, RRID:CVCL_0248)
  
  SciCrunch record: RRID:CVCL_0248
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0248 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0248

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scibot

URL

sciencedirect.com/science/article/pii/S1097276517302046
www.sciencedirect.com www.sciencedirect.com

Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature

1
1. scibot 08 Nov 2017
  
  in Public
  
  CVCL_0248
  
  Curator: @Zeljana_Babic
  
  Resource used:
  
  (TKG Cat# TKG 0379, RRID:CVCL_0248)
  
  SciCrunch record: RRID:CVCL_0248
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0248 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0248

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scibot

URL

sciencedirect.com/science/article/pii/S1535610817301010
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer

1
1. scibot 08 Nov 2017
  
  in Public
  
  CVCL_0248
  
  Curator: @gabimpine
  
  Resource used:
  
  (TKG Cat# TKG 0379, RRID:CVCL_0248)
  
  SciCrunch record: RRID:CVCL_0248
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0248 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:CVCL_0248

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5127641/