259 Matching Annotations
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    FEBS Press
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    Mosperafenib, a novel paradox breaker BRAF inhibitor with potent preclinical activity in BRAF mutated colorectal cancer
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    aacrjournals.org/mct/article/25/4/599/776467/Mosperafenib-a-Novel-Paradox-Breaker-BRAF
  4. Apr 2026
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    Transgelin Expression in Activated Cancer-Associated Fibroblasts Regulates Stromal Contractility and Promotes Colon Cancer Progression
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    AURKA-mediated destabilization of SAPS3 drives ferroptosis evasion via 7-dehydrocholesterol biosynthesis in colorectal cancer
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    Phosphorylation-driven Targeted Protein Degradation of Oncogenic β-catenin
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    biorxiv.org/content/10.64898/2026.03.16.712096v1
  8. Mar 2026
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    ETV4 Promotes Colorectal Cancer Progression by Reprogramming Asparagine Metabolism to Remodel the Stromal Microenvironment
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    A convergent uPAR-positive tumor ecosystem creates broad vulnerability to CAR T cell therapy
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    Intratumoral microbiota and host genotype cooperatively shape neutrophil cytotoxic functions in colorectal cancer
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    sciencedirect.com/science/article/pii/S193131282600051X
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    m1A‐Dependent TRMT6/61A‐ARG2 Axis Drives Protumorigenic Senescence by Remodeling the Tumor Microenvironment
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  14. Feb 2026
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    Placing purines in precision medicine: Targeting a metabolic reliance in KRAS-mutant tumors
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    BRD4-mediated ER membrane contact creates functionally distinct mitochondrial subtypes
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    A comprehensive review of anti-colorectal cancer alkaloids from traditional Chinese medicine: Sources, chemical structures, mechanisms and therapeutic applications
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    Functional characterization of CASP, a CUX1 isoform, reveals its tumor-promoting role in colorectal cancer via TRIM21-mediated signaling
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  21. Jan 2026
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    Thimerosal Inhibits Tumor Malignant Progression through Direct Action and Enhancing the Efficacy of PD-1-Based Immunotherapy
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  28. Dec 2025
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    KRT81 promotes metastasis of colorectal cancer by acting as a protein scaffold for ezrin
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  35. Nov 2025
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  39. Oct 2025
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  53. Aug 2025
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  62. Jul 2025
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The XPO1 inhibitor Eltanexor modulates the Wnt/β-catenin signaling pathway to reduce colorectal cancer tumorigenesis
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    Cetuximab increases LGR5 expression and augments LGR5-targeting antibody-drug conjugate efficacy in patient-derived colorectal cancer models
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    biorxiv.org/content/10.1101/2025.06.18.660406v1
  69. Jun 2025
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    TR-107, An Agonist of Caseinolytic Peptidase Proteolytic Subunit, Disrupts Mitochondrial Metabolism and Inhibits the Growth of Human Colorectal Cancer Cells
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  73. May 2025
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    Discovery of Z1362873773: a novel fascin inhibitor from a large chemical library for colorectal cancer
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  76. Apr 2025
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  79. Mar 2025
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  81. Feb 2025
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    Salicylate-Elicited Activation of AMP-Activated Protein Kinase Directly Triggers Degradation of C-Myc in Colorectal Cancer Cells
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    Identification of Lipid Species Signatures in FOLFOXIRI-Resistant Colorectal Cancer Cells
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  89. Jan 2025
  90. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cell Type Specific Suppression of Hyper-Recombination by Human RAD18 Is Linked to Proliferating Cell Nuclear Antigen K164 Ubiquitination
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    A thermoplastic chip for 2D and 3D correlative assays combining screening and high-resolution imaging of immune cell responses
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    Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation
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  93. Dec 2024
  94. www.cell.com www.cell.com
    Targeting P4HA1 promotes CD8+ T cell progenitor expansion toward immune memory and systemic anti-tumor immunity
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    Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer
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    AMIGO2 characterizes cancer‐associated fibroblasts in metastatic colon cancer and induces the release of paracrine active tumorigenic secretomes
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