898 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    CRL3ARMC5 ubiquitin ligase and Integrator phosphatase form parallel mechanisms to control early stages of RNA Pol II transcription
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    sciencedirect.com/science/article/pii/S1097276524009493
  3. link.springer.com link.springer.com
    LncRNA DANCR-V1 is a novel regulator of Wnt/β-catenin and TGF-β1/SMAD signaling pathways in colorectal cancer: an in vitro and in silico study
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    link.springer.com/article/10.1007/s11033-024-10128-0
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    Inhibiting de novo lipogenesis identifies a therapeutic vulnerability in therapy-resistant colorectal cancer
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    sciencedirect.com/science/article/pii/S2213231724004361
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    Circular RNAs trigger nonsense-mediated mRNA decay
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    sciencedirect.com/science/article/pii/S109727652400947X
  6. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Glucocorticoid promotes metastasis of colorectal cancer via co-regulation of glucocorticoid receptor and TET2
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35285
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optimized reporters for multiplexed detection of transcription factor activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11667439/
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    DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states
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    sciencedirect.com/science/article/pii/S1097276524009146
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    p53 induces circFRMD4A to suppress cancer development through glycolytic reprogramming and cuproptosis
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    sciencedirect.com/science/article/pii/S1097276524009183
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    Biglycan promotes tumour proliferation and invasion in human colon cancers
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    journals.sagepub.com/doi/full/10.1177/03000605241300067
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    The dysadherin/MMP9 axis modifies the extracellular matrix to accelerate colorectal cancer progression
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    nature.com/articles/s41467-024-54920-9
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    Activity-dependent COX-2 proteolysis modulates aerobic respiration and proliferation in a prostaglandin-independent manner
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    sciencedirect.com/science/article/pii/S2589004224026282
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    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
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    sciencedirect.com/science/article/pii/S235239642400495X
  14. Nov 2024
  15. pubs.acs.org pubs.acs.org
    Evaluation of the Combinatory Anticancer Effect of Chemotherapeutic Compounds and Prodigiosin against HCT-116, LoVo, and A549 Cell lines
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    pubs.acs.org/doi/10.1021/acsomega.4c04760
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Histone-acetyl epigenome regulates TGF-β pathway-associated chemoresistance in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11585898/
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    Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint
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    sciencedirect.com/science/article/pii/S107476132400493X
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inter-chromosomal contacts demarcate genome topology along a spatial gradient
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    pmc.ncbi.nlm.nih.gov/articles/PMC11557711/
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    Recognition of BACH1 quaternary structure degrons by two F-box proteins under oxidative stress
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    sciencedirect.com/science/article/pii/S0092867424011887
  20. 52.53.155.43 52.53.155.43
    mcr-24-0433-html.html
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    Replication stress induces POLQ-mediated structural variant formation throughout common fragile sites after entry into mitosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11541566/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bidirectional signals generated by Siglec-7 and its crucial ligand tri-sialylated T to escape of cancer cells from immune surveillance
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    pmc.ncbi.nlm.nih.gov/articles/PMC11539641/
  23. Oct 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined Oxygen-Enhanced MRI and Perfusion Imaging Detect Hypoxia Modification from Banoxantrone and Atovaquone and Track Their Differential Mechanisms of Action
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443776/
  25. www.biorxiv.org www.biorxiv.org
    Metabolic mapping of the human solute carrier superfamily
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    biorxiv.org/content/10.1101/2024.09.23.614124v1
  26. aacrjournals.org aacrjournals.org
    Overproduction of Gastrointestinal 5-HT Promotes Colitis-Associated Colorectal Cancer Progression via Enhancing NLRP3 Inflammasome Activation
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    aacrjournals.org/cancerimmunolres/article/9/9/1008/666146/Overproduction-of-Gastrointestinal-5-HT-Promotes
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    2-Hydroxylation of Fatty Acids Represses Colorectal Tumorigenesis and Metastasis via the YAP Transcriptional Axis
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    aacrjournals.org/cancerres/article/81/2/289/649623/2-Hydroxylation-of-Fatty-Acids-Represses
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    Mitotic ER-mitochondria contact enhances mitochondrial Ca2+ influx to promote cell division
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    sciencedirect.com/science/article/pii/S2211124724011458
  29. Sep 2024
  30. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    CASCADES, a novel SOX2 super-enhancer-associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13735
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13708
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Ctnnb1 enhancer transcriptionally regulates Wnt signaling dosage to balance homeostasis and tumorigenesis of intestinal epithelia
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    ncbi.nlm.nih.gov/pmc/articles/PMC11424096/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRAP1 modulates mitochondrial biogenesis via PGC-1α/TFAM signalling pathway in colorectal cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11416412/
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    Fusobacterium nucleatum facilitates anti-PD-1 therapy in microsatellite stable colorectal cancer
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    sciencedirect.com/science/article/pii/S1535610824003180
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel immunotherapeutics against LGR5 to target multiple cancer types
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    ncbi.nlm.nih.gov/pmc/articles/PMC11393416/
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    Tumour-associated mesenchymal stromal cells modulate macrophage phagocytosis in stromal-rich colorectal cancer via PD-1 signalling.
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    sciencedirect.com/science/article/pii/S2589004224019266
  37. www.biorxiv.org www.biorxiv.org
    Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS-mutated colorectal cancer
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    biorxiv.org/content/10.1101/2024.09.05.611458v1
  38. onlinelibrary.wiley.com onlinelibrary.wiley.com
    14-3-3σ restricts YY1 to the cytoplasm, promoting therapy resistance, and tumor progression in colorectal cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35176
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11372367/
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    TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival
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    sciencedirect.com/science/article/pii/S0092867424009115
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11372369/
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    IDO1 inhibitors are synergistic with CXCL10 agonists in inhibiting colon cancer growth
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    sciencedirect.com/science/article/pii/S0753332224012976
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    Synergistic Anti-tumorigenic Effect of Diosmetin in Combination with 5-Fluorouracil on Human Colon Cancer Xenografts in Nude Mice
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    sciencedirect.com/science/article/pii/S0006291X24012130
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    Five miRNAs identified in fucosylated extracellular vesicles as non-invasive diagnostic signatures for hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2666379124004373
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    Dual function of PHF16 in reinstating homeostasis of murine intestinal epithelium after crypt regeneration
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    sciencedirect.com/science/article/pii/S1534580724004921
  46. Aug 2024
  47. www.sciencedirect.com www.sciencedirect.com
    RNA interacts with topoisomerase I to adjust DNA topology
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    sciencedirect.com/science/article/pii/S1097276524006300
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Jianpi Jiedu Recipe Inhibits Proliferation through Reactive Oxygen Species-Induced Incomplete Autophagy and Reduces PD-L1 Expression in Colon Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11331576/
  49. www.biorxiv.org www.biorxiv.org
    Discovery of Z1362873773: A Novel Fascin Inhibitor from a Large Chemical Library for Colorectal Cancer
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    biorxiv.org/content/10.1101/2024.08.13.606007v1
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC10323897/
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    CCL19-producing fibroblasts promote tertiary lymphoid structure formation enhancing anti-tumor IgG response in colorectal cancer liver metastasis
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    sciencedirect.com/science/article/pii/S153561082400271X
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    Integrative plasma and fecal metabolomics identify functional metabolites in adenoma-colorectal cancer progression and as early diagnostic biomarkers
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    sciencedirect.com/science/article/pii/S1535610824002708
  53. link.springer.com link.springer.com
    Iron Overloading Potentiates the Antitumor Activity of 5-Fluorouracil by Promoting Apoptosis and Ferroptosis in Colorectal Cancer Cells
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    link.springer.com/article/10.1007/s12013-024-01463-x
  54. f1000research.com f1000research.com
    F1000Research Article: Unraveling the Interplay of Autophagy Genes and KLF3/KLF8 in Colorectal Cancer Metastasis: A Bioinformatics and cellular Exploration.
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    f1000research.com/articles/13-850
  55. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16497
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MMP‐9‐dependent proteolysis of the histone H3 N‐terminal tail: a critical epigenetic step in driving oncogenic transcription and colon tumorigenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11306514/
  58. onlinelibrary.wiley.com onlinelibrary.wiley.com
    EEF1D stabilized by SRSF9 promotes colorectal cancer via enhancing the proliferation and metastasis
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35039
  59. www.sciencedirect.com www.sciencedirect.com
    BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism
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    sciencedirect.com/science/article/pii/S1931312824002713
  60. www.cell.com www.cell.com
    Peptostreptococcus stomatis promotes colonic tumorigenesis and receptor tyrosine kinase inhibitor resistance by activating ERBB2-MAPK
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    cell.com/cell-host-microbe/fulltext/S1931-3128(24)00254-3
  61. 52.53.155.43 52.53.155.43
    The Natural Alkaloid (-)- N-Hydroxyapiosporamide Suppresses Colorectal Tumor Progression as an NF-κB Pathway Inhibitor by Targeting the TAK1-TRAF6 Complex
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    52.53.155.43/55175f335d9d63eca4c96b1d663be208d4b843b1/Molecular Oncology - 2023 - Koob - MND1 enables homologous recombination in somatic cells primarily outside the context of-html.html
  63. bmccancer.biomedcentral.com bmccancer.biomedcentral.com
    Intense endoplasmic reticulum stress (ERS) / IRE1α enhanced Oxaliplatin efficacy by decreased ABCC10 in colorectal cancer cells
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    bmccancer.biomedcentral.com/articles/10.1186/s12885-022-10415-8
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-molecule NSC59984 induces mutant p53 degradation through a ROS-ERK2-MDM2 axis in cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8983457/
  65. jeccr.biomedcentral.com jeccr.biomedcentral.com
    Vulnerability to low-dose combination of irinotecan and niraparib in ATM-mutated colorectal cancer
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    jeccr.biomedcentral.com/articles/10.1186/s13046-020-01811-8
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    Therapy-induced DNA methylation inactivates MCT1 and renders tumor cells vulnerable to MCT4 inhibition
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    sciencedirect.com/science/article/pii/S2211124721005519
  67. www.mdpi.com www.mdpi.com
    Targeting AKT/mTOR and Bcl-2 for Autophagic and Apoptosis Cell Death in Lung Cancer: Novel Activity of a Polyphenol Compound
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    mdpi.com/2076-3921/10/4/534/htm
  68. www.embopress.org www.embopress.org
    Unexpected PD‐L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies
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    embopress.org/doi/full/10.15252/emmm.202012716
  69. www.cell.com www.cell.com
    In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30827-3
  70. www.cell.com www.cell.com
    Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30802-9
  71. www.mdpi.com www.mdpi.com
    Diketopiperazine-Based, Flexible Tadalafil Analogues: Synthesis, Crystal Structures and Biological Activity Profile
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    mdpi.com/1420-3049/26/4/794/htm
  72. Jul 2024
  73. www.sciencedirect.com www.sciencedirect.com
    Translocational attenuation mediated by the PERK-SRP14 axis is a protective mechanism of unfolded protein response
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    sciencedirect.com/science/article/pii/S2211124724007307
  74. www.mdpi.com www.mdpi.com
    Upregulation of TET2 and Resistance to DNA Methyltransferase (DNMT) Inhibitors in DNMT1-Deleted Cancer Cells
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    mdpi.com/2079-9721/12/7/163
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterising replisome disassembly in human cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11269944/
  76. www.sciencedirect.com www.sciencedirect.com
    FANCM promotes PARP inhibitor resistance by minimizing ssDNA gap formation and counteracting resection inhibition
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    sciencedirect.com/science/article/pii/S2211124724007939
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    Base-resolution m5C profiling across the mammalian transcriptome by bisulfite-free enzyme-assisted chemical labeling approach
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    sciencedirect.com/science/article/pii/S1097276524005288
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    Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton
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    sciencedirect.com/science/article/pii/S2211124724008398
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    RNA 5-methylcytosine marks mitochondrial double-stranded RNAs for degradation and cytosolic release
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    sciencedirect.com/science/article/pii/S1097276524005306
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    Identification and characterization of TM4SF1+ tumor self-seeded cells
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    sciencedirect.com/science/article/pii/S2211124724008416
  81. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16489
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11230627/
  83. www.cell.com www.cell.com
    A mammalian model reveals inorganic polyphosphate channeling into the nucleolus and induction of a hyper-condensate state
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    cell.com/cell-reports-methods/fulltext/S2667-2375(24)00179-6
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor invasiveness is regulated by the concerted function of APC, formins and Arp2/3 complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC11053316/
  85. Jun 2024
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Illuminating Dark Chemical Matter Using the Cell Painting Assay
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    ncbi.nlm.nih.gov/pmc/articles/PMC11181314/
  87. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Comparing in vitro cytotoxic drug sensitivity in colon and pancreatic cancer using 2D and 3D cell models: Contrasting viability and growth inhibition in clinically relevant dose and repeated drug cycles
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    onlinelibrary.wiley.com/doi/10.1002/cam4.7318
  88. 52.53.155.43 52.53.155.43
    1-s2.0-S258900422400909X-main-html.html
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  89. www.biorxiv.org www.biorxiv.org
    POLQ mediates replication-stress induced structural variant formation throughout common fragile sites during mitosis
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    biorxiv.org/content/10.1101/2024.05.28.596214v1
  90. www.science.org www.science.org
    DNMT3B splicing dysregulation mediated by SMCHD1 loss contributes to DUX4 overexpression and FSHD pathogenesis
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    science.org/doi/10.1126/sciadv.adn7732
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    De novo and salvage purine synthesis pathways across tissues and tumors
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