1,170 Matching Annotations
  1. Feb 2026
  2. www.sciencedirect.com www.sciencedirect.com
    Visceral obesity-induced METTL27 regulation of the FABP5/PPARD/CPT1A axis in promoting colorectal cancer progression
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    sciencedirect.com/science/article/pii/S0141813026006665
  3. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Colorectal cancer-derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70212
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fibroblast-derived POSTN promotes colorectal cancer progression under high-fat diet by reprogramming fatty acid metabolism in tumor cell
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    pmc.ncbi.nlm.nih.gov/articles/PMC12870062/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Microbial Bile Acid Metabolite 3-oxo-LCA Inhibits Colorectal Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12871761/
  6. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Deep Learning-Powered Scalable Cancer Organ Chip for Cancer Precision Medicine
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202516660
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70215
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A nuclear isoform of hydroxyacyl-COA dehydrogenase inhibits tumor progression in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12860641/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Recharacterization of the Tumor Suppressive Mechanism of RSL3 Identifies the Selenoproteome as a Druggable Pathway in Colorectal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12402965/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phillygenin regulates the colorectal cancer tumor microenvironment by inhibiting hypoxia-inducible factor 1 alpha
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    pmc.ncbi.nlm.nih.gov/articles/PMC11631830/
  11. 54.241.53.176 54.241.53.176
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  12. journals.plos.org journals.plos.org
    The lipid-metabolic enzyme HSD17B12 drives lysosomal degradation of PD-L1 potentiating anti-tumor immunity in a mouse model
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    journals.plos.org/plosbiology/article
  13. Jan 2026
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Estrogen-Induced Hypermethylation Silencing of RPS2 and TMEM177 Inhibits Energy Metabolism and Reduces the Survival of CRC Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12839088/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Thimerosal Inhibits Tumor Malignant Progression through Direct Action and Enhancing the Efficacy of PD-1-Based Immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12848756/
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    MYLK4 promotes colorectal cancer progression by regulating lipid metabolism reprogramming via targeting ferroptosis
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    sciencedirect.com/science/article/pii/S1476558625001496
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Revealing the Action Mechanism of Exogenous Hydrogen Sulfide Intervention in Colorectal Cancer Pathogenesis Based on Multiomics Analysis and Experimental Validation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12829476/
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    Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers
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    sciencedirect.com/science/article/pii/S2666379125006500
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    In silico–designed peptide targeting MDR1 (P-gp) restores chemosensitivity in colorectal cancer via chitosan nanoparticle delivery
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    sciencedirect.com/science/article/pii/S1773224726000286
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    Basroparib inhibits YAP-driven cancers by stabilizing angiomotin
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70209
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    The dysadherin/carbonic anhydrase 9 axis shapes an acidic tumor microenvironment to promote colorectal cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12804794/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Consensus Pharmacological Interactions for PLK2 Inhibitor Identification in Colorectal Cancer Treatment
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    pmc.ncbi.nlm.nih.gov/articles/PMC12801292/
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    Targeting TCF21-TCF3 heterodimer in tumor-associated pericytes attenuates hematogenous metastasis by restoring pericyte gatekeeper function
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    sciencedirect.com/science/article/pii/S2666379125006421
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    p53 and fatty acids collaborate to trigger ferroptosis via the FBXO2-FABP5 axis in colorectal cancer
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    sciencedirect.com/science/article/pii/S2213231726000418
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    Mechanistic diversity of Bacteroides fragilis toxins and neutralization with single domain antibody
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    sciencedirect.com/science/article/pii/S2451945625004258
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    Metabolomics reveals that CAF-derived lipids promote colorectal cancer peritoneal metastasis by enhancing membrane fluidity
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    ijbs.com/v18p1912.htm
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Distinct Regulation of the ARF and TAp73 Tumor Suppressor Genes by the Transcription Factor E2F1 Enables Discrimination of Cancer Cells from Normal Growing Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12785935/
  28. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202516588
  29. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Lipid Droplet-Localized Spindle Apparatus Coiled-Coil Protein 1 Regulates Lipid Droplet Distribution
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511960
  30. www.biorxiv.org www.biorxiv.org
    A Novel miR-4745-KLC2 Axis Regulates Cancer Stem Cell Traits in Colorectal Cancer
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    biorxiv.org/content/10.64898/2026.01.07.697660v2
  31. www.jstage.jst.go.jp www.jstage.jst.go.jp
    IFI6 Downregulation Reverses Oxaliplatin Resistance of Colorectal Cancer Cells by Activating the ROS-Induced p38MAPK Signaling Pathway
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    jstage.jst.go.jp/article/bpb/46/1/46_b22-00439/_html/-char/en
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting a Glutamic Acid in PDEδ with Fluoromethyl-Aryl Electrophiles Impairs K-Ras Signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12833852/
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    Dual-faced PUMA in CRC: A cytoplasmic autophagy repressor and mitochondrial mitophagy promoter
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    sciencedirect.com/science/article/pii/S0898656826000124
  34. www-cell-com.eproxy.lib.hku.hk www-cell-com.eproxy.lib.hku.hk
    Single-cell integration and multi-modal profiling reveals phenotypes and spatial organization of neutrophils in colorectal cancer
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    www-cell-com.eproxy.lib.hku.hk/cancer-cell/fulltext/S1535-6108(25)00537-9
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The subtype identification of colorectal cancer and construction of the risk model based on cholesterol synthesis-related genes to predict prognosis and guide immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12789220/
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    Microbial Chemical Diversity and Cytotoxic Potential From Brazilian Ferruginous Caves: A Pioneering Metabolomic Survey
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202502912
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    Targeted nanoparticle delivery of irinotecan enhances tumor response to PD-L1 blockade in colorectal cancer
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    sciencedirect.com/science/article/pii/S0168365926000106
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    UBE2O-mediated monoubiquitination licenses NLRP6 inflammasome activation in the intestine
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    sciencedirect.com/science/article/pii/S1931312825005281
  39. elifesciences.org elifesciences.org
    Candida albicans drives colorectal cancer progression by inducing hypoxia signaling
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    elifesciences.org/reviewed-preprints/108665
  40. www.mdpi.com www.mdpi.com
    A Novel Quinolone JH62 (E-2-(Tridec-4-en-1-yl)-quinolin-4(1H)-one) from Pseudomonas aeruginosa Exhibits Potent Anticancer Activity
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    Cathepsin-D-mediated MHC class I degradation contributes to immune evasion in colorectal cancer
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    sciencedirect.com/science/article/pii/S266637912500607X
  42. Dec 2025
  43. www.sciencedirect.com www.sciencedirect.com
    A TRIM21–UCHL3–ITCH–SIPA1 axis promotes colorectal cancer growth and metastasis
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    sciencedirect.com/science/article/pii/S0304383525007931
  44. 54.241.53.176 54.241.53.176
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  45. www.nature.com www.nature.com
    KRT81 promotes metastasis of colorectal cancer by acting as a protein scaffold for ezrin
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    nature.com/articles/s41388-025-03665-w
  46. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Mitochondrial glutamine import sustains electron transport chain integrity independently of glutaminolysis in cancer
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    sciencedirect.com:5037/science/article/pii/S109727652500975X
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RAS mutation–specific responses to paralog- and state-selective RAS inhibitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12710464/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel β-carboline alkaloid derivative targeting MDM2-p53 pathway suppresses colorectal cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12698734/
  49. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole-3-Acetic Acid
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202519735
  50. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Sec61 translocon inhibitor flavitransin blocks selectively dengue virus polyprotein insertion in the ER with pan-orthoflavivirus antiviral potency
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    sciencedirect.com:5037/science/article/pii/S2211124725014147
  51. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R-Loop Accumulation and DNA Repair Deficiencies
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202512074
  52. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP-ribose) glycohydrolase inhibitor
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70178
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Meta-surface plasmon resonance microscopy for sensitive, high-throughput, and long-term label-free analysis of cell adhesion dynamics
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    pmc.ncbi.nlm.nih.gov/articles/PMC12670785/
  54. 54.241.53.176 54.241.53.176
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  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development of DARPin T cell engagers for specific targeting of tumor-associated HLA/peptide complexes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12664392/
  56. Nov 2025
  57. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    A triple-action PROTAC for wild-type p53 cancer therapy
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    sciencedirect.com:5037/science/article/pii/S2666379125005403
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    A metabolic atlas of mouse aging
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    sciencedirect.com:5037/science/article/pii/S1550413125004760
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Colorectal cancer cell-derived exosomes induce metabolic reprogramming of cancer-associated fibroblasts to promote colorectal cancer growth
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    pmc.ncbi.nlm.nih.gov/articles/PMC12644288/
  60. link.springer.com link.springer.com
    Mitophagy is responsible to ionizing radiation but plays a very limited role in the radiosensitivity of adenocarcinoma cells
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    link.springer.com/article/10.1007/s13577-025-01328-2
  61. www.sciencedirect.com www.sciencedirect.com
    Coastal halophyte plant Atriplex maximowicziana with previously undescribed terpenoids and anti-colorectal cancer chlorophyll stereoisomers utilizing a molecular networking approach
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    sciencedirect.com/org/science/article/pii/S2046206925034059
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP10-mediated deubiquitination and activation of KRAS mutants promotes colorectal cancer via a novel USP10/KRAS positive feedback circuit
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    pmc.ncbi.nlm.nih.gov/articles/PMC12827889/
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Investigating NFE2L1 activators for targeted protein aggregate clearance: a follow-up study
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    pmc.ncbi.nlm.nih.gov/articles/PMC12606464/
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    Developing a therapeutic elastase that stimulates anti-tumor immunity by selectively killing cancer cells
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    sciencedirect.com/science/article/pii/S2666379125005191
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    CDC7 stabilized by KRAS signaling reactivation impairs chemosensitivity in KRAS-mutant colorectal cancer
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    sciencedirect.com/science/article/pii/S1043661825004529
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    2025.11.06.687028v2.full-html.html
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  67. www.biorxiv.org www.biorxiv.org
    The mammalian rapid tRNA decay pathway is critical for N⁷-methylguanosine-hypomodified tRNA degradation under physiological conditions
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    biorxiv.org/content/10.1101/2025.11.05.686800v1
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    WDFY2 promotes MRN complex formation required for homologous recombination-mediated DNA repair
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  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cytoplasmic HMGB1 promotes and interacts with BECN1 through ZNF460 to induce autophagy and accelerate radioresistance in colorectal cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12558843/
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bioactive Compounds, Antioxidant, Antimicrobial and Anticancerogenic Activity in Lacmellea edulis H. Karst., at Different Stages of Maturity
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  71. Oct 2025
  72. www.sciencedirect.com www.sciencedirect.com
    Identification of BET inhibitors (BETi) against solitary fibrous tumor (SFT) through high-throughput screening (HTS)
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    sciencedirect.com/science/article/pii/S1476558625001241
  73. www.biorxiv.org www.biorxiv.org
    L-asparaginase treatment induces a tumor metabolic plasticity and reveals a vulnerability to PARP1/2 inhibitor Olaparib, in B-cell lymphomas
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    biorxiv.org/content/10.1101/2025.10.24.683536v1
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    The E3 ligase RNF32 controls the IκB kinase complex and NF-κB signaling in intestinal stem cells
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    sciencedirect.com/science/article/pii/S1097276525008226
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    Identification of molecular markers and exploration of the oncogenic role of exomeres in hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2211124725012318
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    Highly fluorescent cu/N-codoped carbon dots for selective and sensitive cerium (III) ion detection in food, environmental, and biological samples
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    sciencedirect.com/science/article/pii/S0026265X25032588
  77. rupress.org rupress.org
    PEX14 acts as a molecular link between optineurin and the autophagic machinery to induce pexophagy
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    rupress.org/jcb/article/224/11/e202411184/278363/PEX14-acts-as-a-molecular-link-between-optineurin
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    Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.202501791
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    CANDiT: A machine learning framework for differentiation therapy in colorectal cancer
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  80. www.nature.com www.nature.com
    Enhancing cap-independent translation of linear mRNA
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    nature.com/articles/s41467-025-64257-6
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    A synthetic benzoxazine dimer derivative targets c-Myc to inhibit colorectal cancer progression
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70127
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    CPT1A facilitated ferroptosis by forming feedback loop with Nrf2 via PI3K/AKT pathway in colorectal cancer
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    link.springer.com/article/10.1007/s10495-025-02171-4
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    Tumor-infiltrating bacteria disrupt cancer epithelial cell interactions and induce cell-cycle arrest
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    sciencedirect.com/science/article/pii/S1535610825004027
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cancer-associated fibroblasts expressing FSTL3 promote vasculogenic mimicry formation and drive colon cancer malignancy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12501291/
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    An in vitro tumor recurrence model based on platinum-resistant colon cancer cells as a research tool for studying cancer cell dormancy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12507233/
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    Synergistic anticancer effects of ABT-199 and Vorinostat encapsulated in PLGA nanoparticles: Formulation, characterization, and antiproliferative effects against colorectal cancer cells
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