499 Matching Annotations
  1. Jan 2025
  2. www.sciencedirect.com www.sciencedirect.com
    Anticancer effect of a single-chain variable fragment against pro-matrix metalloproteinase-7 in colon cancer
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    sciencedirect.com/science/article/pii/S0945053X24001513
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    IMPDH2 dephosphorylation under FGFR signaling promotes S-phase progression and tumor growth
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    sciencedirect.com/science/article/pii/S2211124724014670
  4. Dec 2024
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.17371
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11601497/
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    Chlorogenic acid suppresses the expression of matrix metalloproteinase-7 and cell invasiveness to almost the same extent as isofraxidin in human colorectal cancer cells
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    link.springer.com/article/10.1007/s11626-024-00993-1
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    Longitudinal phosphoproteomics reveals the PI3K-PAK1 axis as a potential target for recurrent colorectal liver metastases
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    sciencedirect.com/science/article/pii/S2211124724014128
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13773
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    Anti-Colon Cancer Effects of Lysate from Potential Probiotic Yeast Strains Derived from Human Breast Milk
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    link.springer.com/article/10.1007/s12602-024-10410-4
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    LncRNA DANCR-V1 is a novel regulator of Wnt/β-catenin and TGF-β1/SMAD signaling pathways in colorectal cancer: an in vitro and in silico study
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    link.springer.com/article/10.1007/s11033-024-10128-0
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17350
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    Glucocorticoid promotes metastasis of colorectal cancer via co-regulation of glucocorticoid receptor and TET2
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35285
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    The dysadherin/MMP9 axis modifies the extracellular matrix to accelerate colorectal cancer progression
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    nature.com/articles/s41467-024-54920-9
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    Combining in silico and in vitro approaches for understanding the mechanism of action of the galactomannan extracted from Cassia grandis seeds against colorectal cancer
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    sciencedirect.com/science/article/pii/S0141813024087191
  16. Nov 2024
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    Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint
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    sciencedirect.com/science/article/pii/S107476132400493X
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    Seed sequences mediate off-target activity in the CRISPR-interference system
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    sciencedirect.com/science/article/pii/S2666979X24003227
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    Identification and Characterization of a surfactin from Pseudomonas gessardii: A Symbiotic Bacterium with Potent Anticancer Activity
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    sciencedirect.com/science/article/pii/S0006291X24015250
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    Co-Colorectal cancer stem cells employ the FADS1/DDA axis to evade NK cell-mediated immunosuppression after co-cultured with NK cells under hypoxia
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    sciencedirect.com/science/article/pii/S1567576924020575
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    Design, performance, processing, and validation of a pooled CRISPR perturbation screen for bacterial toxins
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    nature.com/articles/s41596-024-01075-y
  22. Oct 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of O-GlcNAc transferase activates type I interferon-dependent antitumor immunity by bridging cGAS-STING pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC11452177/
  24. aacrjournals.org aacrjournals.org
    Overproduction of Gastrointestinal 5-HT Promotes Colitis-Associated Colorectal Cancer Progression via Enhancing NLRP3 Inflammasome Activation
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    aacrjournals.org/cancerimmunolres/article/9/9/1008/666146/Overproduction-of-Gastrointestinal-5-HT-Promotes
  25. Sep 2024
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    Fusobacterium nucleatum facilitates anti-PD-1 therapy in microsatellite stable colorectal cancer
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    sciencedirect.com/science/article/pii/S1535610824003180
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    Novel immunotherapeutics against LGR5 to target multiple cancer types
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    ncbi.nlm.nih.gov/pmc/articles/PMC11393416/
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    Tumour-associated mesenchymal stromal cells modulate macrophage phagocytosis in stromal-rich colorectal cancer via PD-1 signalling.
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    sciencedirect.com/science/article/pii/S2589004224019266
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    Enhanced pharmacological activities of AKR1C3-activated prodrug AST-3424 in cancer cells with defective DNA repair
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.35170
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11372367/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic Stress-induced Serotonin Impairs Intestinal Epithelial Cell Mitochondrial Biogenesis via the AMPK-PGC-1α Axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11380450/
  32. Aug 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Jianpi Jiedu Recipe Inhibits Proliferation through Reactive Oxygen Species-Induced Incomplete Autophagy and Reduces PD-L1 Expression in Colon Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11331576/
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    CCL19-producing fibroblasts promote tertiary lymphoid structure formation enhancing anti-tumor IgG response in colorectal cancer liver metastasis
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    sciencedirect.com/science/article/pii/S153561082400271X
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    Integrative plasma and fecal metabolomics identify functional metabolites in adenoma-colorectal cancer progression and as early diagnostic biomarkers
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    sciencedirect.com/science/article/pii/S1535610824002708
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor Vessel Normalization via PFKFB3 Inhibition Alleviates Hypoxia and Increases Tumor Necrosis in Rectal Cancer upon Radiotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11310748/
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    Iron Overloading Potentiates the Antitumor Activity of 5-Fluorouracil by Promoting Apoptosis and Ferroptosis in Colorectal Cancer Cells
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    link.springer.com/article/10.1007/s12013-024-01463-x
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    Regulated induced proximity targeting chimeras—RIPTACs—A heterobifunctional small molecule strategy for cancer selective therapies
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    sciencedirect.com/science/article/pii/S2451945624003076
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    BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism
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    sciencedirect.com/science/article/pii/S1931312824002713
  41. www.cell.com www.cell.com
    Peptostreptococcus stomatis promotes colonic tumorigenesis and receptor tyrosine kinase inhibitor resistance by activating ERBB2-MAPK
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    cell.com/cell-host-microbe/fulltext/S1931-3128(24)00254-3
  42. bmccancer.biomedcentral.com bmccancer.biomedcentral.com
    Super-enhancer-associated long noncoding RNA AC005592.2 promotes tumor progression by regulating OLFM4 in colorectal cancer
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    bmccancer.biomedcentral.com/article/10.1186/s12885-021-07900-x
  43. www.cell.com www.cell.com
    RIPK1 Promotes Energy Sensing by the mTORC1 Pathway
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30786-3
  44. Jul 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Putrescine Supplementation Limits the Expansion of pks+ Escherichia coli and Tumor Development in the Colon
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    ncbi.nlm.nih.gov/pmc/articles/PMC11261243/
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    NAMPT-targeting PROTAC and nicotinic acid co-administration elicit safe and robust anti-tumor efficacy in NAPRT-deficient pan-cancers
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    sciencedirect.com/science/article/pii/S2451945624002083
  47. www.cell.com www.cell.com
    Pan-cancer proteogenomics expands the landscape of therapeutic targets
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    cell.com/cell/fulltext/S0092-8674(24)00583-X
  48. www.sciencedirect.com www.sciencedirect.com
    Retinoic acid enhances HIV-1 reverse transcription and transcription in macrophages via mTOR-modulated mechanisms
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    sciencedirect.com/science/article/pii/S2211124724007435
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    Redox-dependent plasticity of oxMIF facilitates its interaction with CD74 and therapeutic antibodies
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  50. www.nature.com www.nature.com
    Cell-cell contact-dependent secretion of large-extracellular vesicles from EFNBhigh cancer cells accelerates peritoneal dissemination
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    nature.com/articles/s41416-024-02783-8
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    Secretion of IL-6 and TGF-β2 by Colon Cancer Cells May Promote Resistance to Chemotherapy
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    link.springer.com/article/10.1007/s12291-024-01247-3
  52. May 2024
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Assessment of chemotherapeutic effects on cancer cells using adhesion noise spectroscopy
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    A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
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    sciencedirect.com/science/article/pii/S1074761324002309
  55. aacrjournals.org aacrjournals.org
    NRAS mutant dictates AHCYL1-governed ER calcium homeostasis for melanoma tumor growth
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    aacrjournals.org/mcr/article/22/4/386/741848/NRAS-Mutant-Dictates-AHCYL1-Governed-ER-Calcium
  56. 52.53.155.43 52.53.155.43
    Metabolic reprogramming of hypoxic tumour-associated macrophages through CSF-1R targeting favours treatment efficiency in colorectal cancers
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    IL-22 promotes mucin-type O-glycosylation and MATH1+ cell-mediated amelioration of intestinal inflammation
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  58. 52.53.155.43 52.53.155.43
    SIRT1 mediates the antagonism of Wnt/β-catenin pathway by vitamin D in colon carcinoma cells
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  59. Apr 2024
  60. www.sciencedirect.com www.sciencedirect.com
    Exogenous non-coding dsDNA-dependent trans-activation of phagocytes augments anti-tumor immunity
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    sciencedirect.com/science/article/pii/S2666379124001976
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    O-GlcNAcylation of RBM14 contributes to elevated cellular O-GlcNAc through regulation of OGA protein stability
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Type I interferon regulation by USP18 is a key vulnerability in cancer
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  63. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    Downregulation of ABCC3 activates MAPK signaling through accumulation of deoxycholic acid in colorectal cancer cells
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    Multifunctional host-defense peptides isolated from skin secretions of the banana tree dwelling frog Boana platanera (Hylidae; Hylinae)
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  66. Mar 2024
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    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced chemokine C‐C motif ligand 1 expression may negatively regulate colorectal cancer progression at liver metastatic sites
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    ncbi.nlm.nih.gov/pmc/articles/PMC10952021/
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor acidosis-induced DNA damage response and tetraploidy enhance sensitivity to ATM and ATR inhibitors
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    HIF-1α Mediates Immunosuppression and Chemoresistance in Colorectal Cancer by Inhibiting CXCL9, −10 and −11
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  72. Feb 2024
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    Roseburia intestinalis sensitizes colorectal cancer to radiotherapy through the butyrate/OR51E1/RALB axis
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    BAMLET administration via drinking water inhibits intestinal tumor development and promotes long-term health
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    link.springer.com/article/10.1038/s41598-024-54040-w
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    A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers
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    Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting
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  78. www.mdpi.com www.mdpi.com
    Stratification of Colorectal Patients Based on Survival Analysis Shows the Value of Consensus Molecular Subtypes and Reveals the CBLL1 Gene as a Biomarker of CMS2 Tumours
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831336/
  80. Jan 2024
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased response to immune checkpoint inhibitors with dietary methionine restriction
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  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10187264/
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    PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis
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  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning
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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aldolase B-driven lactagenesis and CEACAM6 activation promote cell renewal and chemoresistance in colorectal cancer through the Warburg effect
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    ncbi.nlm.nih.gov/pmc/articles/PMC10564793/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction in a Colorectal Cancer Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC10526448/
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    A comprehensive clinically informed map of dependencies in cancer cells and framework for target prioritization
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    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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  89. Dec 2023
  90. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transcript CD81-215 may be a long noncoding RNA of stromal origin with tumor-promoting role in colon cancer
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    onlinelibrary.wiley.com/doi/full/10.1002/cbf.3890
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Cell Surface-Binding Antibody Atlas Nominates a MUC18-Directed Antibody–Drug Conjugate for Targeting Melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10646479/
  92. Oct 2023
  93. www.sciencedirect.com www.sciencedirect.com
    Lactate activates the mitochondrial electron transport chain independently of its metabolism
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    FEBS Press
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    52.53.155.43/081c581c43e0c0f25916aa7621bfda2e34b6f467/Molecular Oncology - 2023 - Everest-Dass - Spontaneous metastasis xenograft models link CD44 isoform 4 to angiogenesis -html.html
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A fingerprint of 2-[18F]FDG radiometabolites – how tissue-specific metabolism beyond 2-[18F]FDG-6-phosphate could affect tracer accumulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10585399/
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatial Profiling of Circular RNAs in Cancer Reveals High Expression in Muscle and Stromal Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10570686/
  97. www.nature.com www.nature.com
    INVADEseq to identify cell-adherent or invasive bacteria and the associated host transcriptome at single-cell-level resolution
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    nature.com/articles/s41596-023-00888-7
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    Biodistribution of mRNA COVID-19 vaccines in human breast milk
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