366 Matching Annotations
  1. Aug 2025
  2. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Lifespan-Regulated CAR-Macrophages from Myeloid Progenitors for Enhanced Colorectal Cancer Therapy
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202417677
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    YTHDF proteins and m6A-RNA clients undergo autophagic turnover during contact inhibition
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    sciencedirect.com/science/article/pii/S2211124725009593
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    TCF25 serves as a nutrient sensor to orchestrate metabolic adaptation and cell death by enhancing lysosomal acidification under glucose starvation
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    sciencedirect.com/science/article/pii/S221112472500957X
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    Chebulinic acid shields Villin 1 from covalent attack to mitigate Euphorbia fischeriana enterotoxicity: A basis for safer anti-ascites therapy
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    sciencedirect.com/science/article/pii/S0378874125011274
  6. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Novel Role of Gut-Derived Roseburia Intestinalis in Safeguarding Intestinal Barrier Integrity and Microenvironment Homeostasis During Arsenic Exposure
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511895
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    RNA Pol II inhibition activates cell death independently from the loss of transcription
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    cell.com/cell/fulltext/S0092-8674(25)00856-6
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tissue-dependent mechanosensing by cells derived from human tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12328224/
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    The exopolysaccharides from Streptococcus mutans ATCC 35668 for inhibiting the growth of HT-29 colorectal cancer cell line
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    sciencedirect.com/science/article/pii/S3050475925005688
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    Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression
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    sciencedirect.com/science/article/pii/S1535610825003186
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pericytes promote metastasis by regulating tumor local vascular tone and hemodynamics
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    pmc.ncbi.nlm.nih.gov/articles/PMC12318036/
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    Pharmacodynamic analyses of LAT1 inhibitors in vitro and in vivo by targeted metabolomics reveal target-independent effects
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    sciencedirect.com/science/article/pii/S0753332225005967
  13. Jul 2025
  14. www.biorxiv.org www.biorxiv.org
    Biomechanical Phenotyping Reveals Unique Mechanobiological Signatures of Early-Onset Colorectal Cancer
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    biorxiv.org/content/10.1101/2025.07.15.664829v1
  15. 52.53.155.43 52.53.155.43
    Forkhead box M1 mediates metabolic reprogramming in human colorectal cancer cells | American Journal of Physiology-Gastrointestinal and Liver Physiology
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    52.53.155.43/560f52b699bc9e3c55f364712d862fc9e7752a6b/li-et-al-2024-forkhead-box-m1-mediates-metabolic-reprogramming-in-human-colorectal-cancer-cells-html.html
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The XPO1 inhibitor Eltanexor modulates the Wnt/β-catenin signaling pathway to reduce colorectal cancer tumorigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12260813/
  17. www.sciencedirect.com www.sciencedirect.com
    Substitution of a proline residue in the frog skin host-defense peptide, figainin-2PL by D-lysine generates an analog with potent activity against antibiotic-resistant ESKAPE pathogens
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    sciencedirect.com/science/article/pii/S0196978125000919
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    Separation-of-function mutants reveal the NF-κB-independent involvement of IκBα in the regulation of intestinal stemness
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    sciencedirect.com/science/article/pii/S221112472500720X
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuro-mesenchymal interaction mediated by a β2 adrenergic-nerve growth factor feedforward loop promotes colorectal cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11729495/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    2D and 3D in vitro photodynamic activities of tetra-substituted symmetric water-soluble cationic zinc(II) phthalocyanines on cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12254502/
  21. www.science.org www.science.org
    Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression
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    science.org/doi/10.1126/science.adv2861
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    Identification of UBE3C as an E3 ubiquitin ligase for mutant BRAF
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    sciencedirect.com/science/article/pii/S002432052500462X
  23. 52.53.155.43 52.53.155.43
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    bpspubs.onlinelibrary.wiley.com/doi/10.1002/prp2.70132
  25. aacrjournals.org aacrjournals.org
    Development of a Novel DNA Mono-alkylator Platform for Antibody Drug Conjugates
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    aacrjournals.org/mct/article/23/4/541/741864/Development-of-a-Novel-DNA-Mono-alkylator-Platform
  26. journals.physiology.org journals.physiology.org
    Filamin A C-terminal fragment modulates Orai1 expression by inhibition of protein degradation | American Journal of Physiology-Cell Physiology | American Physiological Society
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    journals.physiology.org/doi/full/10.1152/ajpcell.00745.2024
  27. journals.physiology.org journals.physiology.org
    Filamin A C-terminal fragment modulates Orai1 expression by inhibition of protein degradation
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    journals.physiology.org/doi/10.1152/ajpcell.00745.2024
  28. Jun 2025
  29. www.cell.com www.cell.com
    BAG2 releases SAMD4B upon sensing of arginine deficiency to promote tumor cell survival
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    cell.com/molecular-cell/fulltext/S1097-2765(25)00499-X
  30. www.sciencedirect.com www.sciencedirect.com
    RIPK1 senses S-adenosylmethionine scarcity to drive cell death and inflammation
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    sciencedirect.com/science/article/pii/S1550413125002943
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Itaconate and obesity-related hormones promote tumor progression – new insights on metabolic dysfunction in early-onset colon cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12183228/
  32. www.sciencedirect.com www.sciencedirect.com
    Pre-clinical characterization of novel multi-client inhibitors of Sec61 with broad anti-tumor activity
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    sciencedirect.com/science/article/pii/S0022356525398472
  33. www.pnas.org www.pnas.org
    Epithelial Regnase-1 inhibits colorectal tumor growth by regulating IL-17 signaling via degradation of <i>NFKBIZ</i> mRNA
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    pnas.org/doi/abs/10.1073/pnas.2500820122
  34. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Germline pathogenic variants in HIC1 DNA binding domains are associated with familial serrated polyposis syndrome
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35492
  35. 52.53.155.43 52.53.155.43
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    Flagellar switch inverted repeats impact heterogeneity in flagellar gene expression and thus C. difficile RT027/MLST1 virulence
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    sciencedirect.com/science/article/pii/S2211124725006011
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TR-107, An Agonist of Caseinolytic Peptidase Proteolytic Subunit, Disrupts Mitochondrial Metabolism and Inhibits the Growth of Human Colorectal Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11614700/
  38. link.springer.com link.springer.com
    Anti-Inflammatory Effect and Gut Health of Levilactobacillus brevis Strains in Macrophage and Intestinal Cells
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    link.springer.com/article/10.1007/s12602-025-10621-3
  39. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Integrin β6 expression in colorectal cancer cells promotes liver metastasis through enhanced adhesion to endothelial fibronectin
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35504
  40. May 2025
  41. www.sciencedirect.com www.sciencedirect.com
    Bacteroides sphingolipids promote anti-inflammatory responses through the mevalonate pathway
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    sciencedirect.com/science/article/pii/S1931312825001866
  42. www.sciencedirect.com www.sciencedirect.com
    Bacteroides fragilis promotes chemoresistance in colorectal cancer, and its elimination by phage VA7 restores chemosensitivity
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    sciencedirect.com/science/article/pii/S1931312825001830
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metformin reverses 5-FU resistance induced by radiotherapy through mediating folate metabolism in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12093704/
  44. www.sciencedirect.com www.sciencedirect.com
    Novel Approaches to 3D Cancer Heterospheroid Culture and Assay Development for Immunotherapy Screening
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    sciencedirect.com/science/article/pii/S0014482725002009
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    Integrative proteomic profiling of tumor and plasma extracellular vesicles identifies a diagnostic biomarker panel for colorectal cancer
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    sciencedirect.com/science/article/pii/S2666379125001636
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    Extrachromosomal DNA replication and maintenance couple with DNA damage pathway in tumors
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    sciencedirect.com/science/article/pii/S0092867425004143
  47. Apr 2025
  48. www.sciencedirect.com www.sciencedirect.com
    ZBP1 senses splicing aberration through Z-RNA to promote cell death
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    sciencedirect.com/science/article/pii/S1097276525002990
  49. microbiomejournal.biomedcentral.com microbiomejournal.biomedcentral.com
    Initial gut microbiota composition is a determining factor in the promotion of colorectal cancer by oral iron supplementation: evidence from a murine model
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    microbiomejournal.biomedcentral.com/articles/10.1186/s40168-025-02101-1
  50. www.sciencedirect.com www.sciencedirect.com
    ARID3A inhibits colorectal cancer cell stemness and drug-resistance by targeting a multitude of stemness-associated genes
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    sciencedirect.com/science/article/pii/S0024320525002772
  51. www.sciencedirect.com www.sciencedirect.com
    A new EGFR and c-Met bispecific NIR-II fluorescent probe for visualising colorectal cancer and metastatic lymph nodes
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    sciencedirect.com/science/article/pii/S2352396425001318
  52. www.sciencedirect.com www.sciencedirect.com
    Streptomycin targets tumor-initiating cells by disrupting oxidative phosphorylation
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    sciencedirect.com/science/article/pii/S2451945625000984
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    N6-methyladenosine in DNA promotes genome stability
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    pmc.ncbi.nlm.nih.gov/articles/PMC11975372/
  54. www.sciencedirect.com www.sciencedirect.com
    The imidazoline I2 receptor agonist 2-BFI enhances cytotoxic activity of hydroxychloroquine by modulating oxidative stress , energy-related metabolism and autophagic influx in human colorectal adenocarcinoma cell lines
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    sciencedirect.com/science/article/pii/S0014299925003449
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    VAX014 Activates Tumor-Intrinsic STING and RIG-I to Promote the Development of Antitumor Immunity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962400/
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Augmenting CAR T Cell Functions with LIGHT
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    pmc.ncbi.nlm.nih.gov/articles/PMC11444887/
  57. Mar 2025
  58. 52.53.155.43 52.53.155.43
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  61. link.springer.com link.springer.com
    Antitumor effects of immunotherapy combined with BRAF and MEK inhibitors in BRAF V600E metastatic colorectal cancer
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    link.springer.com/article/10.1007/s00262-025-04005-3
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The CD64/CD28/CD3ζ chimeric receptor reprograms T-cell metabolism and promotes T-cell persistence and immune functions while triggering antibody-independent and antibody-dependent cytotoxicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11834217/
  63. Feb 2025
  64. www.mdpi.com www.mdpi.com
    Peptide Fractions Extracted from the Hemolymph of Hermetia illucens Inhibit Growth and Motility and Enhance the Effects of Traditional Chemotherapeutics in Human Colorectal Cancer Cells
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    mdpi.com/1422-0067/26/5/1891
  65. www.sciencedirect.com www.sciencedirect.com
    Targeting both the enzymatic and non-enzymatic functions of DHODH as a therapeutic vulnerability in c-Myc-driven cancer
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    sciencedirect.com/science/article/pii/S2211124725000981
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The integrated stress response drives MET oncogene overexpression in cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11832788/
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Potent, Selective, Small-Molecule Inhibitor of DHX9 Abrogates Proliferation of Microsatellite Instable Cancers with Deficient Mismatch Repair
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    pmc.ncbi.nlm.nih.gov/articles/PMC11831107/
  68. aacrjournals.org aacrjournals.org
    Serotonin receptor HTR2B facilitates colorectal cancer metastasis via CREB1-ZEB1 axis mediated epithelial-mesenchymal transition
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    aacrjournals.org/mcr/article/22/6/538/745428/Serotonin-Receptor-HTR2B-Facilitates-Colorectal
  69. aacrjournals.org aacrjournals.org
    Th17 cells secrete TWEAK to trigger epithelial-mesenchymal transition and promote colorectal cancer liver metastasis
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    aacrjournals.org/cancerres/article/84/8/1352/742976/Th17-Cells-Secrete-TWEAK-to-Trigger-Epithelial
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A ‘torn bag mechanism’ of small extracellular vesicle release via limiting membrane rupture of en bloc released amphisomes (amphiectosomes)
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    pmc.ncbi.nlm.nih.gov/articles/PMC11805505/
  71. Jan 2025
  72. 52.53.155.43 52.53.155.43
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  73. www.sciencedirect.com www.sciencedirect.com
    Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation
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    sciencedirect.com/science/article/pii/S1074761324005685
  74. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.17422
  75. www.sciencedirect.com www.sciencedirect.com
    Anticancer effect of a single-chain variable fragment against pro-matrix metalloproteinase-7 in colon cancer
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    sciencedirect.com/science/article/pii/S0945053X24001513
  76. www.sciencedirect.com www.sciencedirect.com
    IMPDH2 dephosphorylation under FGFR signaling promotes S-phase progression and tumor growth
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    sciencedirect.com/science/article/pii/S2211124724014670
  77. Dec 2024
  78. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.17371
  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11601497/
  80. link.springer.com link.springer.com
    Chlorogenic acid suppresses the expression of matrix metalloproteinase-7 and cell invasiveness to almost the same extent as isofraxidin in human colorectal cancer cells
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    link.springer.com/article/10.1007/s11626-024-00993-1
  81. www.sciencedirect.com www.sciencedirect.com
    Longitudinal phosphoproteomics reveals the PI3K-PAK1 axis as a potential target for recurrent colorectal liver metastases
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    sciencedirect.com/science/article/pii/S2211124724014128
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13773
  83. link.springer.com link.springer.com
    Anti-Colon Cancer Effects of Lysate from Potential Probiotic Yeast Strains Derived from Human Breast Milk
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    link.springer.com/article/10.1007/s12602-024-10410-4
  84. link.springer.com link.springer.com
    LncRNA DANCR-V1 is a novel regulator of Wnt/β-catenin and TGF-β1/SMAD signaling pathways in colorectal cancer: an in vitro and in silico study
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    link.springer.com/article/10.1007/s11033-024-10128-0
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17350
  86. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Glucocorticoid promotes metastasis of colorectal cancer via co-regulation of glucocorticoid receptor and TET2
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35285
  87. www.nature.com www.nature.com
    The dysadherin/MMP9 axis modifies the extracellular matrix to accelerate colorectal cancer progression
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    nature.com/articles/s41467-024-54920-9
  88. www.sciencedirect.com www.sciencedirect.com
    Combining in silico and in vitro approaches for understanding the mechanism of action of the galactomannan extracted from Cassia grandis seeds against colorectal cancer
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    sciencedirect.com/science/article/pii/S0141813024087191
  89. Nov 2024
  90. www.sciencedirect.com www.sciencedirect.com
    Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint
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    sciencedirect.com/science/article/pii/S107476132400493X
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    Seed sequences mediate off-target activity in the CRISPR-interference system
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    sciencedirect.com/science/article/pii/S2666979X24003227
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    Identification and Characterization of a surfactin from Pseudomonas gessardii: A Symbiotic Bacterium with Potent Anticancer Activity
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    sciencedirect.com/science/article/pii/S0006291X24015250
  93. www.sciencedirect.com www.sciencedirect.com
    Co-Colorectal cancer stem cells employ the FADS1/DDA axis to evade NK cell-mediated immunosuppression after co-cultured with NK cells under hypoxia
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