415 Matching Annotations
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    Targeting a Glutamic Acid in PDEδ with Fluoromethyl-Aryl Electrophiles Impairs K-Ras Signaling
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    Revealing the Action Mechanism of Exogenous Hydrogen Sulfide Intervention in Colorectal Cancer Pathogenesis Based on Multiomics Analysis and Experimental Validation
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    Pan-cancer N-glycoproteomic atlas of patient-derived xenografts uncovers FAT2 as an actionable surface target
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    New applications of sustainable, scalable, standardized, and cost-effective human biomaterials for cell-based assays, tissue engineering, and regenerative medicine
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    Medicago Sativa L. Saponin‐Driven Lactobacillus Intestinalis Restores Intestinal Stemness in Naturally Aged Mice via the Bile Acid‐FXR‐Wnt Signaling Axis
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  7. Jan 2026
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    The dysadherin/carbonic anhydrase 9 axis shapes an acidic tumor microenvironment to promote colorectal cancer progression
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    Immune gene diversity and STING1 variants in shaping cancer immunity across different genetic ancestry populations
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    Consensus Pharmacological Interactions for PLK2 Inhibitor Identification in Colorectal Cancer Treatment
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    CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistance
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    Lactobacillus delbrueckii surface protein P4430 attenuates intestinal inflammation by modulating macrophage polarization via Mincle
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    USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer
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    Single-cell integration and multi-modal profiling reveals phenotypes and spatial organization of neutrophils in colorectal cancer
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    KRASG12/13 mutation modulates CRC outcomes via disrupting positive feedback between macrophage and CD4+ T cell
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    Long non-coding RNA UCA1 modulates SMARCA2-containing SWI/SNF chromatin remodeling complexes in human colorectal cancer
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  18. Dec 2025
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    A TRIM21–UCHL3–ITCH–SIPA1 axis promotes colorectal cancer growth and metastasis
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    In mouse and in vitro models, bowel preparation promotes pathogen colonization, translocation, and exacerbation of inflammation
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    A novel β-carboline alkaloid derivative targeting MDM2-p53 pathway suppresses colorectal cancer progression
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    Exploiting the Biogenic Potential of Spirulina platensis for the Sustainable Synthesis of Multifunctional and Bioactive Magnesium Oxide Nanoparticles
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    Design, synthesis, and structural elucidation of ethyl 2-amino-5-oxo-4-aryl-4 H -pyrano[3,2- c ]quinoline-3-carboxylates as dual EGFR/HER-2 inhibitors endowed with antiproliferative activity
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  25. Nov 2025
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    Colorectal cancer cell-derived exosomes induce metabolic reprogramming of cancer-associated fibroblasts to promote colorectal cancer growth
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    USP10-mediated deubiquitination and activation of KRAS mutants promotes colorectal cancer via a novel USP10/KRAS positive feedback circuit
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  36. Oct 2025
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    Purinergic Ecto-Enzyme CD73 is a Context-Dependent Tumor Suppressor in Colorectal Cancer
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    CPT1A facilitated ferroptosis by forming feedback loop with Nrf2 via PI3K/AKT pathway in colorectal cancer
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    MM-129 Counteracts 5-Fluorouracil-Induced Cellular Senescence in Colon Cancer via SIRT1/STAT3 Signaling Pathway
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    Limited activation interdependence and differing patterns of the in vivo effects of IKK1 and IKK2 downstream of NIK
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  48. Sep 2025
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  56. Aug 2025
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  68. Jul 2025
  69. www.biorxiv.org www.biorxiv.org
    Biomechanical Phenotyping Reveals Unique Mechanobiological Signatures of Early-Onset Colorectal Cancer
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    The XPO1 inhibitor Eltanexor modulates the Wnt/β-catenin signaling pathway to reduce colorectal cancer tumorigenesis
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    Substitution of a proline residue in the frog skin host-defense peptide, figainin-2PL by D-lysine generates an analog with potent activity against antibiotic-resistant ESKAPE pathogens
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    2D and 3D in vitro photodynamic activities of tetra-substituted symmetric water-soluble cationic zinc(II) phthalocyanines on cancer
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    Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression
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    Identification of UBE3C as an E3 ubiquitin ligase for mutant BRAF
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    Development of a Novel DNA Mono-alkylator Platform for Antibody Drug Conjugates
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    Filamin A C-terminal fragment modulates Orai1 expression by inhibition of protein degradation | American Journal of Physiology-Cell Physiology | American Physiological Society
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    Filamin A C-terminal fragment modulates Orai1 expression by inhibition of protein degradation
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  83. Jun 2025
  84. www.cell.com www.cell.com
    BAG2 releases SAMD4B upon sensing of arginine deficiency to promote tumor cell survival
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    Epithelial Regnase-1 inhibits colorectal tumor growth by regulating IL-17 signaling via degradation of <i>NFKBIZ</i> mRNA
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    Germline pathogenic variants in HIC1 DNA binding domains are associated with familial serrated polyposis syndrome
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