467 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High-throughput screening identifies NT-1 that synergizes with MRTX1133 against acquired resistant KRASG12D colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13249833/
  3. Jun 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DDR1 Promotes Immune Evasion in Colorectal Cancer by Orchestrating IL33-Mediated M2-like Polarization of Tumor-Associated Macrophages
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    pmc.ncbi.nlm.nih.gov/articles/PMC13227095/
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    Triple-armed oncolytic HSV enhances antitumor immunity by remodeling the tumor microenvironment in subcutaneous murine CRC
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    sciencedirect.com/science/article/pii/S2589004226012587
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    Plasma - Activated Medium Engages Redox Signaling to Activate a VDAC1–TRPML1 Lysosomal–Mitochondrial Ca2+ Death Pathway
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    sciencedirect.com/science/article/pii/S0891584926008488
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    Exploring Synergistic Potential of Sorafenib and Atorvastatin to Launch Apoptosis and Ferroptosis-driven Mixed Cell Death Mechanism in Colorectal Cancer
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    link.springer.com/article/10.1208/s12249-026-03461-z
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    Repurposing Artesunate to Combat Progression and Metastasis via Targeting Circulating Tumor Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13223190/
  9. May 2026
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Non-Temperature-Induced Antitumor Effects of Amplitude-Modulated Radiofrequency: Molecular and Functional Synergies with Radiotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13204345/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Triptolide enhances anti-cancer activities of irinotecan in human colon cancer HT-29 cells in vitro and HT-29 cell xenograft tumor model in nude mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC13201951/
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    Tumor-draining lymph nodes in ovarian cancer lack germinal centers but harbor tumor-reactive memory B cells clonally linked to intra-tumoral B cells
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    sciencedirect.com/science/article/pii/S1074761326001792
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    CAMK1 Suppresses Anoikis Resistance and Liver Metastasis in Colorectal Cancer
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    faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202600481RR
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    Targeting ADAR1 p150 triggers tumor inhibition and antitumor immunity to overcome immunotherapy resistance
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    sciencedirect.com/science/article/pii/S2589004226013532
  15. analyticalsciencejournals.onlinelibrary.wiley.com analyticalsciencejournals.onlinelibrary.wiley.com
    Synergistic Anticancer Effects of Akkermansia muciniphila Combined With 5-Fluorouracil Through BAX/BCL2 Dependent Apoptosis in Colorectal Cancer Cells
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    analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/cbf.70234
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    iRGD-functionalized PLGA nanocomplex co-loaded with paclitaxel and Trametes robiniophila Murr for targeted inhibition of chemoresistant and metastatic signaling gene PDCD4 in colon cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13173983/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Betrixaban activates cGAS and ERVs to promote dual nucleic-sensing antiviral immunity
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    pmc.ncbi.nlm.nih.gov/articles/PMC13179341/
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    ISG15 negatively regulates RIPK3-mediated cell death and viral pathogenesis
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    Metabolic stress conditions dictate MAPKAPK2-dependent efficiency of MEK1/2 inhibition in colorectal carcinoma
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  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IFITM1-targeted NIR-II fluorescence imaging enables visualisation of colorectal cancer and metastatic lymph nodes
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    pmc.ncbi.nlm.nih.gov/articles/PMC13134288/
  21. Apr 2026
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    The cytotoxic effect of prexasertib is a consequence of dual inhibition on both CHK1 and AMPK
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  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hypoxic CAF studies unveil PTHrP-vitamin D-RAS axis as pivotal in the CAF
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    pmc.ncbi.nlm.nih.gov/articles/PMC13107517/
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    Protocol to identify covalent inhibitors targeting RhoA Cys16
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  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ASCL2 drives colorectal cancer metastasis through transcriptional activation of TDGF1
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  26. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Phenolic Profiles and Cytotoxic Activities of Methanolic Extracts From Eight Geranium L. Species
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202503814
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    Synthesis and characterization of NIR-sensitive curcumin-gelatin nanoparticles for targeted drug delivery in 3D colon cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13076676/
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    Mosperafenib, a novel paradox breaker BRAF inhibitor with potent preclinical activity in BRAF mutated colorectal cancer
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    Integrative Multiomics and Single‐Cell Analyses Identify FKBP10 as a Predictor of Radiotherapy Outcome in Colorectal Cancer
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  30. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Structure-Guided Synthetic Peptide Targeting Nucleolus and Neural Progenitor Protein Nuclear Import Impairs Ribosome Biogenesis and Cancer Cell Proliferation
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    Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer
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    IAP-based biodegraders can convert necroptosis to apoptosis and eliminate cancer driving protein complexes
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    EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS-STING Pathway
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  34. Mar 2026
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    Early-stage multi-cancer detection through a plasma extracellular vesicle protein signature
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    HMGB1 reduce DNA damage by binding KU70 to activate NHEJ pathway in colorectal cancer cells after radiation
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    CGF induces ROS-mediated metabolic reprogramming and mitochondrial dysfunction to suppress colorectal cancer progression
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    Autoinhibitory control of MLKL governs pseudokinase domain phosphorylation and oligomerization during necroptosis
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    A bispecific nanobody-drug conjugate targeting TROP2 and c-Met for low-concentration, single-dose treatment of pancreatic cancer
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    Pooled single-cell screen in colorectal cancer defines transcriptional modules linked to oncogenes
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    Nigakinone enhances FXR expression to synergize with irinotecan in suppressing colorectal cancer cells and xenografts
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    Lysine-11 ubiquitination drives type-I/III interferon induction by cGAS–STING and Toll-like receptors 3 and 4
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    nature.com/articles/s41556-026-01886-z
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    Pentatropis capensis-Derived Phyto-Compounds: In Silico Analysis Targeting of DCAF1/VprBP in Colorectal Cancer and Biochemical Studies
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  45. Feb 2026
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    Global mapping of circRNA-target RNA interactions reveal P-body-mediated translational repression
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    A comprehensive review of anti-colorectal cancer alkaloids from traditional Chinese medicine: Sources, chemical structures, mechanisms and therapeutic applications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70343
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    Functional characterization of CASP, a CUX1 isoform, reveals its tumor-promoting role in colorectal cancer via TRIM21-mediated signaling
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    Compartmentalized branched-chain amino acid metabolism orchestrates colorectal cancer dissemination via an UMP-vimentin axis
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    sciencedirect.com/science/article/pii/S1550413126000070
  50. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Colorectal cancer-derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver
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  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fibroblast-derived POSTN promotes colorectal cancer progression under high-fat diet by reprogramming fatty acid metabolism in tumor cell
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    pmc.ncbi.nlm.nih.gov/articles/PMC12870062/
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    Multi-Target Anticancer Activity of Justicia betonica L.: Phytochemical Profiling, In Silico Screening, and Preclinical Evaluation
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    Deep Learning-Powered Scalable Cancer Organ Chip for Cancer Precision Medicine
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    Gut microbiota-derived isovaleric acid alleviates atrial fibrillation by suppressing GSDME-dependent pyroptosis
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  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epithelial Gab1 Restricts Sepsis‐Induced Intestinal Injury by Orchestrating TNF/NF‐κB Axis
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  57. Jan 2026
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Thimerosal Inhibits Tumor Malignant Progression through Direct Action and Enhancing the Efficacy of PD-1-Based Immunotherapy
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    Targeting a Glutamic Acid in PDEδ with Fluoromethyl-Aryl Electrophiles Impairs K-Ras Signaling
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    Revealing the Action Mechanism of Exogenous Hydrogen Sulfide Intervention in Colorectal Cancer Pathogenesis Based on Multiomics Analysis and Experimental Validation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12829476/
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    Pan-cancer N-glycoproteomic atlas of patient-derived xenografts uncovers FAT2 as an actionable surface target
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    New applications of sustainable, scalable, standardized, and cost-effective human biomaterials for cell-based assays, tissue engineering, and regenerative medicine
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  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Medicago Sativa L. Saponin‐Driven Lactobacillus Intestinalis Restores Intestinal Stemness in Naturally Aged Mice via the Bile Acid‐FXR‐Wnt Signaling Axis
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    The dysadherin/carbonic anhydrase 9 axis shapes an acidic tumor microenvironment to promote colorectal cancer progression
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    Immune gene diversity and STING1 variants in shaping cancer immunity across different genetic ancestry populations
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    Consensus Pharmacological Interactions for PLK2 Inhibitor Identification in Colorectal Cancer Treatment
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    CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistance
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    Lactobacillus delbrueckii surface protein P4430 attenuates intestinal inflammation by modulating macrophage polarization via Mincle
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    Mechanistic diversity of Bacteroides fragilis toxins and neutralization with single domain antibody
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    USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202516588
  71. www-cell-com.eproxy.lib.hku.hk www-cell-com.eproxy.lib.hku.hk
    Single-cell integration and multi-modal profiling reveals phenotypes and spatial organization of neutrophils in colorectal cancer
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    KRASG12/13 mutation modulates CRC outcomes via disrupting positive feedback between macrophage and CD4+ T cell
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    Long non-coding RNA UCA1 modulates SMARCA2-containing SWI/SNF chromatin remodeling complexes in human colorectal cancer
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  74. Dec 2025
  75. www.sciencedirect.com www.sciencedirect.com
    A TRIM21–UCHL3–ITCH–SIPA1 axis promotes colorectal cancer growth and metastasis
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    In mouse and in vitro models, bowel preparation promotes pathogen colonization, translocation, and exacerbation of inflammation
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    A novel β-carboline alkaloid derivative targeting MDM2-p53 pathway suppresses colorectal cancer progression
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  78. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Exploiting the Biogenic Potential of Spirulina platensis for the Sustainable Synthesis of Multifunctional and Bioactive Magnesium Oxide Nanoparticles
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202502550
  79. pubs.rsc.org pubs.rsc.org
    Design, synthesis, and structural elucidation of ethyl 2-amino-5-oxo-4-aryl-4 H -pyrano[3,2- c ]quinoline-3-carboxylates as dual EGFR/HER-2 inhibitors endowed with antiproliferative activity
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  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sustained reductions in valine and isoleucine mediate anti-cancer pharmacological effects of inhibiting amino acid transporter LAT1 in cancer cells
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  81. Nov 2025
  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Colorectal cancer cell-derived exosomes induce metabolic reprogramming of cancer-associated fibroblasts to promote colorectal cancer growth
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    The diagnostic value of miR-340-5p in pediatric ulcerative colitis and its molecular mechanism by targeting MAP3K2 to modulate intestinal epithelial cell dysfunction
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    Coastal halophyte plant Atriplex maximowicziana with previously undescribed terpenoids and anti-colorectal cancer chlorophyll stereoisomers utilizing a molecular networking approach
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  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP10-mediated deubiquitination and activation of KRAS mutants promotes colorectal cancer via a novel USP10/KRAS positive feedback circuit
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    Developing a therapeutic elastase that stimulates anti-tumor immunity by selectively killing cancer cells
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    CDC7 stabilized by KRAS signaling reactivation impairs chemosensitivity in KRAS-mutant colorectal cancer
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  89. elifesciences.org elifesciences.org
    The Shigella flexneri effector IpaH1.4 facilitates RNF213 degradation and protects cytosolic bacteria against interferon-induced ubiquitylation
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