367 Matching Annotations
  1. Sep 2023
  2. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Kleszcz-html.html
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    52.53.155.43/bda5ca2ff5fc6352261b5aa6b5327e2f6367b095/British J Pharmacology - 2023 - Kleszcz-html.html
  3. Aug 2023
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10463307/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10405072/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Palbociclib suppresses the cancer stem cell properties and cell proliferation through increased levels of miR-506 or miR-150 in Panc-1 and MiaPaCa-2 cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10387936/
  7. Jul 2023
  8. www.sciencedirect.com www.sciencedirect.com
    Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
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    sciencedirect.com/science/article/pii/S0092867423006967
  9. Jun 2023
  10. www.sciencedirect.com www.sciencedirect.com
    Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells
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    sciencedirect.com/science/article/pii/S2451945623001551
  11. www.nature.com www.nature.com
    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
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    nature.com/articles/s41467-023-39241-7
  12. aacrjournals.org aacrjournals.org
    Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer
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    aacrjournals.org/cancerres/article/83/5/735/716680/Enhanced-Glutaminolysis-Drives-Hypoxia-Induced
  13. www.sciencedirect.com www.sciencedirect.com
    Phosphoproteomics guides effective low-dose drug combinations against pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124723005922
  14. May 2023
  15. www.nature.com www.nature.com
    Roundabout homolog 1 inhibits proliferation via the YY1-ROBO1-CCNA2-CDK2 axis in human pancreatic cancer
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    nature.com/articles/s41388-021-01741-5
  16. onlinelibrary.wiley.com onlinelibrary.wiley.com
    KMT2D links TGF-β signaling to noncanonical activin pathway and regulates pancreatic cancer cell plasticity
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34528
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10152234/
  18. www.sciencedirect.com www.sciencedirect.com
    Pharmacological ascorbate induces sustained mitochondrial dysfunction
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    sciencedirect.com/science/article/pii/S0891584923004008
  19. Apr 2023
  20. link.springer.com link.springer.com
    Activation of Vitamin D/VDR Signaling Reverses Gemcitabine Resistance of Pancreatic Cancer Cells Through Inhibition of MUC1 Expression
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    link.springer.com/article/10.1007/s10620-023-07931-3
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950
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    ncbi.nlm.nih.gov/pmc/articles/PMC10112292/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10069867/
  23. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13425
  24. 52.53.155.43 52.53.155.43
    A group of novel VEGF splice variants as alternative therapeutic targets in renal cell carcinoma
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    52.53.155.43/50807bad4ac98194c420b81c9bc8a62408d03259/Molecular Oncology - 2023 - Montemagno - A group of novel VEGF splice variants as alternative therapeutic targets in renal-html.html
  25. Mar 2023
  26. www.spandidos-publications.com www.spandidos-publications.com
    HNF1A regulates oxaliplatin resistance in pancreatic cancer by targeting 53BP1
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    spandidos-publications.com/10.3892/ijo.2023.5493
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZL-1211 Exhibits Robust Antitumor Activity by Enhancing ADCC and Activating NK Cell–mediated Inflammation in CLDN18.2-High and -Low Expressing Gastric Cancer Models
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10010325/
  28. www.nature.com www.nature.com
    Non-canonical functions of SNAIL drive context-specific cancer progression
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    nature.com/articles/s41467-023-36505-0
  29. Feb 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Global profiling of AMG510 modified proteins identified tumor suppressor KEAP1 as an off-target
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    sciencedirect.com/science/article/pii/S2589004223001578
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stress Granules determine the Development of Obesity-associated Pancreatic Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9357213/
  32. Jan 2023
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PhAc-ALGP-Dox, a Novel Anticancer Prodrug with Targeted Activation and Improved Therapeutic Index
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    ncbi.nlm.nih.gov/pmc/articles/PMC9377749/
  34. www.nature.com www.nature.com
    NF-κB/RelA controlled A20 limits TRAIL-induced apoptosis in pancreatic cancer
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    nature.com/articles/s41419-022-05535-9
  35. www.mdpi.com www.mdpi.com
    Identification of Genes Associated with Liver Metastasis in Pancreatic Cancer Reveals PCSK6 as a Crucial Mediator
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    mdpi.com/2072-6694/15/1/241
  36. Dec 2022
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    JNK inhibitor IX restrains pancreatic cancer through p53 and p21
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    ncbi.nlm.nih.gov/pmc/articles/PMC9768178/
  38. www.sciencedirect.com www.sciencedirect.com
    The Sag-Shoc2 axis regulates conversion of mPanINs to cystic lesions in Kras pancreatic tumor model
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    sciencedirect.com/science/article/pii/S2211124722017296
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9737747/
  40. Nov 2022
  41. www.sciencedirect.com www.sciencedirect.com
    Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer
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    sciencedirect.com/science/article/pii/S2666379122003743
  42. www.sciencedirect.com www.sciencedirect.com
    NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124722014942
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutrophils in pancreatic cancer: Potential therapeutic targets
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    ncbi.nlm.nih.gov/pmc/articles/PMC9618950/
  44. Oct 2022
  45. aacrjournals.org aacrjournals.org
    Selenium modulates cancer cell response to pharmacologic ascorbate
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    aacrjournals.org/cancerres/article/82/19/3486/709413/Selenium-Modulates-Cancer-Cell-Response-to
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    XDec-CHI reveals immunosuppressive interactions in pancreatic ductal adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9579012/
  47. link.springer.com link.springer.com
    Proteome alterations during clonal isolation of established human pancreatic cancer cell lines
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    link.springer.com/article/10.1007/s00018-022-04584-9
  48. Sep 2022
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC9271144/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EMT-induced gemcitabine resistance in pancreatic cancer involves the functional loss of equilibrative nucleoside transporter 1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9464091/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decellularization of xenografted tumors provides cell-specific in vitro 3D environment
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    ncbi.nlm.nih.gov/pmc/articles/PMC9434107/
  52. Aug 2022
  53. insight.jci.org insight.jci.org
    Axon guidance receptor ROBO3 modulates subtype identity and prognosis via AXL-associated inflammatory network in pancreatic cancer
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    insight.jci.org/articles/view/154475
  54. link.springer.com link.springer.com
    CDK7 inhibition augments response to multidrug chemotherapy in pancreatic cancer
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    link.springer.com/article/10.1186/s13046-022-02443-w
  55. Jul 2022
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KRAS mutant-driven SUMOylation controls extracellular vesicle transmission to trigger lymphangiogenesis in pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9282935/
  57. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Exploring the potential of exosomes in diagnosis and drug delivery for PDAC
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34195
  58. www.researchsquare.com www.researchsquare.com
    Home
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    researchsquare.com/article/rs-7216019/'https://www.researchsquare.com/article/rs-7216019/v1
  59. link.springer.com link.springer.com
    Lipocalin-2 inhibits pancreatic cancer stemness via the AKT/c-Jun pathway
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    link.springer.com/article/10.1007/s13577-022-00735-z
  60. 52.53.155.43 52.53.155.43
    157644.1-20220517111248-covered-e0fd13ba177f913fd3156f593ead4cfd-html.html
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    52.53.155.43/6ff2513f1a3b330377acc02bf74475e062a26292/157644.1-20220517111248-covered-e0fd13ba177f913fd3156f593ead4cfd-html.html
  61. Jun 2022
  62. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Remediating Desmoplasia with EGFR-Targeted Photoactivable Multi-Inhibitor Liposomes Doubles Overall Survival in Pancreatic Cancer
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    onlinelibrary.wiley.com/doi/10.1002/advs.202104594
  63. www.sciencedirect.com www.sciencedirect.com
    GPR120 promotes metastasis but inhibits tumor growth in pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S1424390322001983
  64. Apr 2022
  65. www.sciencedirect.com www.sciencedirect.com
    Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes
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    sciencedirect.com/science/article/pii/S2211124722003886
  66. www.nature.com www.nature.com
    Patient-derived pancreatic cancer-on-a-chip recapitulates the tumor microenvironment
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    nature.com/articles/s41378-022-00370-6
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UHMK1 Is a Novel Marker for Personalized Prediction of Pancreatic Cancer Prognosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8960145/
  68. Mar 2022
  69. www.embopress.org www.embopress.org
    Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression
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    embopress.org/doi/abs/10.15252/embj.2021110466
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases
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    ncbi.nlm.nih.gov/pmc/articles/PMC8919295/
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of mitochondrial fission by GIPC-mediated Drp1 retrograde transport
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    ncbi.nlm.nih.gov/pmc/articles/PMC8886816/
  72. cmbl.biomedcentral.com cmbl.biomedcentral.com
    TMEM43 promotes pancreatic cancer progression by stabilizing PRPF3 and regulating RAP2B/ERK axis
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    cmbl.biomedcentral.com/articles/10.1186/s11658-022-00321-z
  73. Feb 2022
  74. link.springer.com link.springer.com
    Novel role of the Mu-opioid receptor in pancreatic cancer: potential link between opioid use and cancer progression
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    link.springer.com/article/10.1007/s11010-022-04377-5
  75. link.springer.com link.springer.com
    Romidepsin and tamoxifen cooperatively induce senescence of pancreatic cancer cells through downregulation of FOXM1 expression and induction of reactive oxygen species/lipid peroxidation
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    link.springer.com/article/10.1007/s11033-022-07192-9
  76. Jan 2022
  77. www.molbiolcell.org www.molbiolcell.org
    Regulation of mitochondrial fission by GIPC-mediated Drp1 retrograde transport
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    molbiolcell.org/doi/abs/10.1091/mbc.E21-06-0286
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 Screen Identifies DYRK1A as a Target for Radiotherapy Sensitization in Pancreatic Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8773906/
  79. www.sciencedirect.com www.sciencedirect.com
    Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells
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    sciencedirect.com/science/article/pii/S2211124721017459
  80. journals.sagepub.com journals.sagepub.com
    Complex Tumor Spheroids, a Tissue-Mimicking Tumor Model, for Drug Discovery and Precision Medicine - Gurmeet Kaur, David M. Evans, Beverly A. Teicher, Nathan P. Coussens, 2021
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    journals.sagepub.com/doi/full/10.1177/24725552211038362
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyaluronic acid fuels pancreatic cancer cell growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC8730721/
  82. Dec 2021
  83. www.sciencedirect.com www.sciencedirect.com
    Protein modifications throughout the lung cancer proteome unravel the cancer-specific regulation of glycolysis
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    sciencedirect.com/science/article/pii/S2211124721016338
  84. journals.sagepub.com journals.sagepub.com
    Complex Tumor Spheroids, a Tissue-Mimicking Tumor Model, for Drug Discovery and Precision Medicine - Gurmeet Kaur, David M. Evans, Beverly A. Teicher, Nathan P. Coussens, 2021
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    journals.sagepub.com/doi/full/10.1177/24725552211038362
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glutamine deprivation triggers NAGK-dependent hexosamine salvage
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    ncbi.nlm.nih.gov/pmc/articles/PMC8631944/
  86. www.nature.com www.nature.com
    Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer
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    nature.com/articles/s42003-021-02842-3
  87. www.sciencedirect.com www.sciencedirect.com
    CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment
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    sciencedirect.com/science/article/pii/S2211124721015461
  88. Nov 2021
  89. www.sciencedirect.com www.sciencedirect.com
    A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer
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    sciencedirect.com/science/article/pii/S004520682100883X
  90. journals.sagepub.com journals.sagepub.com
    Complex Tumor Spheroids, a Tissue-Mimicking Tumor Model, for Drug Discovery and Precision Medicine - Gurmeet Kaur, David M. Evans, Beverly A. Teicher, Nathan P. Coussens, 2021
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    journals.sagepub.com/doi/full/10.1177/24725552211038362
  91. www.nature.com www.nature.com
    Upregulating sirtuin 6 ameliorates glycolysis, EMT and distant metastasis of pancreatic adenocarcinoma with krüppel-like factor 10 deficiency
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    nature.com/articles/s12276-021-00687-8
  92. www.nature.com www.nature.com
    AKIRIN2 controls the nuclear import of proteasomes in vertebrates
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    nature.com/articles/s41586-021-04035-8
  93. Oct 2021
  94. www.nature.com www.nature.com
    Analysis of clonogenic growth in vitro
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    nature.com/articles/s41596-021-00615-0
  95. Sep 2021
  96. www.sciencedirect.com www.sciencedirect.com
    Oncogene-dependent sloppiness in mRNA translation
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    sciencedirect.com/science/article/pii/S109727652100736X
  97. Aug 2021
  98. www.sciencedirect.com www.sciencedirect.com
    Enhancement of gemcitabine efficacy by K73-03 via epigenetically regulation of miR-421/SPINK1 in gemcitabine resistant pancreatic cancer cells
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    sciencedirect.com/science/article/pii/S0944711321002543
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VHH212 nanobody targeting the hypoxia-inducible factor 1α suppresses angiogenesis and potentiates gemcitabine therapy in pancreatic cancer in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC8330535/
  100. europepmc.org europepmc.org
    Untitled document
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    europepmc.org/articles/PMC6037479/
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6226003/
  102. link.springer.com link.springer.com
    Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy
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    link.springer.com/article/10.1186/s40170-019-0202-2
  103. Jul 2021
  104. www.sciencedirect.com www.sciencedirect.com
    DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters
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    sciencedirect.com/science/article/pii/S221112471931527X
  105. www.sciencedirect.com www.sciencedirect.com
    Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism
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    sciencedirect.com/science/article/pii/S2211124719312446
  106. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers
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    sciencedirect.com/science/article/pii/S2211124719311520
  107. www.sciencedirect.com www.sciencedirect.com
    EGFR-Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis
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    sciencedirect.com/science/article/pii/S153458071930485X
  108. www.sciencedirect.com www.sciencedirect.com
    KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism
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    sciencedirect.com/science/article/pii/S1535610818304677
  109. www.sciencedirect.com www.sciencedirect.com
    Establishment of live-cell-based coupled assay system for identification of compounds to modulate metabolic activities of cells
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    sciencedirect.com/science/article/pii/S2211124721006872
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8238250/
  111. Jun 2021
  112. www.sciencedirect.com www.sciencedirect.com
    Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
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