414 Matching Annotations
  1. Apr 2024
  2. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ELAPOR1 induces the classical/progenitor subtype and contributes to reduced disease aggressiveness through metabolic reprogramming in pancreatic cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34960
  3. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    ITIH5 as a multifaceted player in pancreatic cancer suppression, impairing tyrosine kinase signaling, cell adhesion and migration
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13609
  4. www.sciencedirect.com www.sciencedirect.com
    The UBE2F-CRL5ASB11-DIRAS2 axis is an oncogene and tumor suppressor cascade in pancreatic cancer cells
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    sciencedirect.com/science/article/pii/S1534580724001837
  5. Mar 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Roflumilast inhibits tumor growth and migration in STK11/LKB1 deficient pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10924943/
  7. www.sciencedirect.com www.sciencedirect.com
    PRMT1 promotes pancreatic cancer development and resistance to chemotherapy
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    sciencedirect.com/science/article/pii/S2666379124001058
  8. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/47007dbc2cda4f961c79d2e8158521ca8af7c5b7/Molecular Oncology - 2023 - Bots - Preclinical evaluation of the gorilla-derived HAdV-B AdV-lumc007 oncolytic adenovirus -html.html
  9. Feb 2024
  10. 52.53.155.43 52.53.155.43
    176-html.html
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    52.53.155.43/2ec0d88e67b798a89b6c5516dbe547b3b2c5ce80/176-html.html
  11. aacrjournals.org aacrjournals.org
    Mitochondrial translocase TOMM22 is overexpressed in pancreatic cancer and promotes aggressive growth by modulating mitochondrial protein import and function
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    aacrjournals.org/mcr/article/22/2/197/733695/Mitochondrial-Translocase-TOMM22-Is-Overexpressed
  12. aacrjournals.org aacrjournals.org
    Nuclear GRP78 Promotes Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Ductal Adenocarcinoma
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    aacrjournals.org/clincancerres/article/29/24/5183/731660/Nuclear-GRP78-Promotes-Metabolic-Reprogramming-and
  13. www.sciencedirect.com www.sciencedirect.com
    A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers
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    sciencedirect.com/science/article/pii/S2666379124000570
  14. 52.53.155.43 52.53.155.43
    Identification of an H-Ras nanocluster disrupting peptide
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    52.53.155.43/50febc729cb1f3f2f29f241e3592121bf7d8fba9/2023.09.07.556635v1.full-html.html
  15. 52.53.155.43 52.53.155.43
    An improved PDE6D inhibitor combines with Sildenafil to synergistically inhibit KRAS mutant cancer cell growth
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    52.53.155.43/d64025fcba7405c73976a9e0dc65e9989e0d835f/2023.08.23.554263v1.full-html.html
  16. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16289
  17. www.biorxiv.org www.biorxiv.org
    A common druggable signature of oncogenic CMYC, mutant KRAS and mutant p53 reveals functional redundancy and competition of the oncogenes in cancer
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    biorxiv.org/content/10.1101/2023.12.20.572548v1
  18. www.sciencedirect.com www.sciencedirect.com
    Palmitoylation alters LDHA activity and pancreatic cancer response to chemotherapy
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    sciencedirect.com/science/article/abs/pii/S0304383524000892
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nudt21-mediated alternative polyadenylation of MZT1 3’UTR contributes to pancreatic cancer progression
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831950/
  20. Jan 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A new animal product free defined medium for 2D and 3D culturing of normal and cancer cells to study cell proliferation and migration as well as dose response to chemical treatment
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    ncbi.nlm.nih.gov/pmc/articles/PMC10313884/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10187264/
  23. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Citric acid promotes SPARC release in pancreatic cancer cells and inhibits the progression of pancreatic tumors in mice on a high-fat diet
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17058
  24. transmedcomms.biomedcentral.com transmedcomms.biomedcentral.com
    iMN041 is an immunotherapeutic and an effective treatment in mouse xenograft models of pancreatic cancer, renal cancer and triple negative breast cancer
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    transmedcomms.biomedcentral.com/articles/10.1186/s41231-024-00161-3
  25. www.mdpi.com www.mdpi.com
    Multi-Algorithm Analysis Reveals Pyroptosis-Linked Genes as Pancreatic Cancer Biomarkers
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    mdpi.com/2072-6694/16/2/372
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chimeric antibody targeting unique epitope on onco-mucin16 reduces tumor burden in pancreatic and lung malignancies
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    ncbi.nlm.nih.gov/pmc/articles/PMC10421872/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic analysis reveals HDAC1 regulates clinically relevant transcriptional programs in Pancreatic cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10666341/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Suppression of the KRAS-NRF2 axis shifts arginine into the phosphocreatine energy system in pancreatic cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10746371/
  29. www.sciencedirect.com www.sciencedirect.com
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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    sciencedirect.com/science/article/pii/S1097276523010225
  30. www.sciencedirect.com www.sciencedirect.com
    Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death
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    sciencedirect.com/science/article/pii/S0092867423013478
  31. www.sciencedirect.com www.sciencedirect.com
    KH-like domains in PARP9/DTX3L and PARP14 coordinate protein-protein interactions to promote cancer cell survival
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    sciencedirect.com/science/article/pii/S002228362300551X
  32. Dec 2023
  33. www.sciencedirect.com www.sciencedirect.com
    PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition
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    sciencedirect.com/science/article/pii/S2666379123005438
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deuterium Magnetic Resonance Imaging Using Deuterated Water-Induced 2H-Tissue Labeling Allows Monitoring Cancer Treatment at Clinical Field Strength
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    ncbi.nlm.nih.gov/pmc/articles/PMC10722130/
  35. www.sciencedirect.com www.sciencedirect.com
    Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability
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    sciencedirect.com/science/article/pii/S2211124723015152
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Cell Surface-Binding Antibody Atlas Nominates a MUC18-Directed Antibody–Drug Conjugate for Targeting Melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10646479/
  37. 52.53.155.43 52.53.155.43
    mcr-23-0138-html.html
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    52.53.155.43/35aec9dc6d388b7cf372e8caf56749d4ccbc7935/mcr-23-0138-html.html
  38. 52.53.155.43 52.53.155.43
    ccr-23-1143-html.html
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    52.53.155.43/aa509a782208f9df8c6754b69c5c07021388a9c4/ccr-23-1143-html.html
  39. Nov 2023
  40. www.sciencedirect.com www.sciencedirect.com
    SERPINB3-MYC axis induces the basal-like/squamous subtype and enhances disease progression in pancreatic cancer
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    sciencedirect.com/science/article/pii/S2211124723014468
  41. www.biorxiv.org www.biorxiv.org
    LMO3 is a suppressor of the basal-like/squamous PDAC subtype and reduces disease aggressiveness of pancreatic cancer through glycerol 3-phosphate metabolism
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    biorxiv.org/content/10.1101/2023.11.01.564448v1
  42. www.sciencedirect.com www.sciencedirect.com
    In vivo bioluminescence imaging of labile iron in xenograft models and liver using FeAL-1, an iron-activatable form of D-luciferin
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    sciencedirect.com/science/article/pii/S2451945623003252
  43. Oct 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Synergistic antitumor efficacy of rMV-Hu191 and Olaparib in pancreatic cancer by generating oxidative DNA damage and ROS-dependent apoptosis
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    sciencedirect.com/science/article/pii/S1936523323001985
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impact of CRISPR/Cas9-Mediated CD73 Knockout in Pancreatic Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10572021/
  46. 52.53.155.43 52.53.155.43
    ccr-23-1635-html.html
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    52.53.155.43/ca2b195ea38c3b689515eb400fe86dc0dba1dbca/ccr-23-1635-html.html
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined Targeting of NAD Biosynthesis and the NAD-dependent Transcription Factor C-terminal Binding Protein as a Promising Novel Therapy for Pancreatic Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10549224/
  48. Sep 2023
  49. www.biorxiv.org www.biorxiv.org
    ELAPOR1 induces the classical/progenitor subtype and contributes to reduced disease aggressiveness through metabolic reprogramming in pancreatic cancer
    1
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    biorxiv.org/content/10.1101/2023.09.23.558894v1
  50. www.sciencedirect.com www.sciencedirect.com
    Deubiquitinating PABPC1 by USP10 upregulates CLK2 translation to promote tumor progression in pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/abs/pii/S0304383523003622
  51. link.springer.com link.springer.com
    Use of Native-PAGE for the Identification of Epichaperomes in Cell Lines
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    link.springer.com/protocol/10.1007/978-1-0716-3342-7_14
  52. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Removal of gemcitabine-induced senescent cancer cells by targeting glutaminase1 improves the therapeutic effect in pancreatic ductal adenocarcinoma
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34725
  53. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Collagen XVII regulates tumor growth in pancreatic cancer through interaction with the tumor microenvironment
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    onlinelibrary.wiley.com/doi/10.1111/cas.15952
  54. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Kleszcz-html.html
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    52.53.155.43/bda5ca2ff5fc6352261b5aa6b5327e2f6367b095/British J Pharmacology - 2023 - Kleszcz-html.html
  55. Aug 2023
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10463307/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10405072/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Palbociclib suppresses the cancer stem cell properties and cell proliferation through increased levels of miR-506 or miR-150 in Panc-1 and MiaPaCa-2 cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10387936/
  59. Jul 2023
  60. www.sciencedirect.com www.sciencedirect.com
    Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
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    sciencedirect.com/science/article/pii/S0092867423006967
  61. Jun 2023
  62. www.sciencedirect.com www.sciencedirect.com
    Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells
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    sciencedirect.com/science/article/pii/S2451945623001551
  63. www.nature.com www.nature.com
    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
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    nature.com/articles/s41467-023-39241-7
  64. aacrjournals.org aacrjournals.org
    Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer
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    aacrjournals.org/cancerres/article/83/5/735/716680/Enhanced-Glutaminolysis-Drives-Hypoxia-Induced
  65. www.sciencedirect.com www.sciencedirect.com
    Phosphoproteomics guides effective low-dose drug combinations against pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124723005922
  66. May 2023
  67. www.nature.com www.nature.com
    Roundabout homolog 1 inhibits proliferation via the YY1-ROBO1-CCNA2-CDK2 axis in human pancreatic cancer
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    nature.com/articles/s41388-021-01741-5
  68. onlinelibrary.wiley.com onlinelibrary.wiley.com
    KMT2D links TGF-β signaling to noncanonical activin pathway and regulates pancreatic cancer cell plasticity
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34528
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10152234/
  70. www.sciencedirect.com www.sciencedirect.com
    Pharmacological ascorbate induces sustained mitochondrial dysfunction
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    sciencedirect.com/science/article/pii/S0891584923004008
  71. Apr 2023
  72. link.springer.com link.springer.com
    Activation of Vitamin D/VDR Signaling Reverses Gemcitabine Resistance of Pancreatic Cancer Cells Through Inhibition of MUC1 Expression
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    link.springer.com/article/10.1007/s10620-023-07931-3
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950
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    ncbi.nlm.nih.gov/pmc/articles/PMC10112292/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10069867/
  75. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13425
  76. 52.53.155.43 52.53.155.43
    A group of novel VEGF splice variants as alternative therapeutic targets in renal cell carcinoma
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    52.53.155.43/50807bad4ac98194c420b81c9bc8a62408d03259/Molecular Oncology - 2023 - Montemagno - A group of novel VEGF splice variants as alternative therapeutic targets in renal-html.html
  77. Mar 2023
  78. www.spandidos-publications.com www.spandidos-publications.com
    HNF1A regulates oxaliplatin resistance in pancreatic cancer by targeting 53BP1
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    spandidos-publications.com/10.3892/ijo.2023.5493
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZL-1211 Exhibits Robust Antitumor Activity by Enhancing ADCC and Activating NK Cell–mediated Inflammation in CLDN18.2-High and -Low Expressing Gastric Cancer Models
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10010325/
  80. www.nature.com www.nature.com
    Non-canonical functions of SNAIL drive context-specific cancer progression
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    nature.com/articles/s41467-023-36505-0
  81. Feb 2023
  82. www.sciencedirect.com www.sciencedirect.com
    Global profiling of AMG510 modified proteins identified tumor suppressor KEAP1 as an off-target
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    sciencedirect.com/science/article/pii/S2589004223001578
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stress Granules determine the Development of Obesity-associated Pancreatic Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9357213/
  84. Jan 2023
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PhAc-ALGP-Dox, a Novel Anticancer Prodrug with Targeted Activation and Improved Therapeutic Index
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    ncbi.nlm.nih.gov/pmc/articles/PMC9377749/
  86. www.nature.com www.nature.com
    NF-κB/RelA controlled A20 limits TRAIL-induced apoptosis in pancreatic cancer
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    nature.com/articles/s41419-022-05535-9
  87. www.mdpi.com www.mdpi.com
    Identification of Genes Associated with Liver Metastasis in Pancreatic Cancer Reveals PCSK6 as a Crucial Mediator
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    mdpi.com/2072-6694/15/1/241
  88. Dec 2022
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    JNK inhibitor IX restrains pancreatic cancer through p53 and p21
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    ncbi.nlm.nih.gov/pmc/articles/PMC9768178/
  90. www.sciencedirect.com www.sciencedirect.com
    The Sag-Shoc2 axis regulates conversion of mPanINs to cystic lesions in Kras pancreatic tumor model
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    sciencedirect.com/science/article/pii/S2211124722017296
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9737747/
  92. Nov 2022
  93. www.sciencedirect.com www.sciencedirect.com
    Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer
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    sciencedirect.com/science/article/pii/S2666379122003743
  94. www.sciencedirect.com www.sciencedirect.com
    NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124722014942
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutrophils in pancreatic cancer: Potential therapeutic targets
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    ncbi.nlm.nih.gov/pmc/articles/PMC9618950/
  96. Oct 2022
  97. aacrjournals.org aacrjournals.org
    Selenium modulates cancer cell response to pharmacologic ascorbate
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    aacrjournals.org/cancerres/article/82/19/3486/709413/Selenium-Modulates-Cancer-Cell-Response-to
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    XDec-CHI reveals immunosuppressive interactions in pancreatic ductal adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9579012/
  99. link.springer.com link.springer.com
    Proteome alterations during clonal isolation of established human pancreatic cancer cell lines
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    link.springer.com/article/10.1007/s00018-022-04584-9
  100. Sep 2022
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC9271144/
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EMT-induced gemcitabine resistance in pancreatic cancer involves the functional loss of equilibrative nucleoside transporter 1
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