312 Matching Annotations
  1. Aug 2022
  2. www.sciencedirect.com www.sciencedirect.com
    Identification of potent inhibitors of SARS-CoV-2 infection by combined pharmacological evaluation and cellular network prioritization
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    sciencedirect.com/science/article/pii/S258900422201197X
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    NMDA receptor-targeted enrichment of CaMKIIα improves fear memory
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    sciencedirect.com/science/article/pii/S2589004222011361
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8831451/
  5. Jul 2022
  6. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15904
  7. Jun 2022
  8. 52.53.155.43 52.53.155.43
    cd-21-0646-html.html
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    52.53.155.43/8eb6598be53599407b5cdbf0aa5958efcfba5063/cd-21-0646 (2)-html.html
  9. 52.53.155.43 52.53.155.43
    mct-21-0682-html.html
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    52.53.155.43/ab9f52410f4c75a7a2713f4530b957e6dadc45f9/mct-21-0682-html.html
  10. www.sciencedirect.com www.sciencedirect.com
    Endogenous spacing enables co-processing of microRNAs and efficient combinatorial RNAi
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    sciencedirect.com/science/article/pii/S2667237522001084
  11. portlandpress.com portlandpress.com
    APLNR Regulates IFN-γ signaling via β-arrestin 1 mediated JAK-STAT1 pathway in melanoma cells
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    portlandpress.com/biochemj/article/479/3/385/230705/APLNR-Regulates-IFN-signaling-via-arrestin-1
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    Active APPL1 sequestration by Plasmodium favors liver-stage development
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    sciencedirect.com/science/article/pii/S2211124722006611
  13. May 2022
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    ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1
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    sciencedirect.com/science/article/pii/S1097276522004348
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Matricellular protein WISP2 is an endogenous inhibitor of collagen linearization and cancer metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8595651/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A somatic mutation in moesin drives progression into acute myeloid leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC9020775/
  17. Apr 2022
  18. www.science.org www.science.org
    A somatic mutation in moesin drives progression into acute myeloid leukemia
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    science.org/doi/full/10.1126/sciadv.abm9987
  19. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Serotonin 5-HT7 receptor overexpression in the raphe nuclei area produces antidepressive effect and affects brain serotonin system in male mice
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    onlinelibrary.wiley.com/doi/10.1002/jnr.25055
  20. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage
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    sciencedirect.com/science/article/pii/S1534580722002295
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncogenic Herpesvirus Engages Endothelial Transcription Factors SOX18 and PROX1 to Increase Viral Genome Copies and Virus Production
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    ncbi.nlm.nih.gov/pmc/articles/PMC8985843/
  22. www.sciencedirect.com www.sciencedirect.com
    Melanomas with concurrent BRAF non-p.V600 and NF1 loss-of-function mutations are targetable by BRAF/MEK inhibitor combination therapy
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    sciencedirect.com/science/article/pii/S2211124722003862
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MLL5 is involved in retinal photoreceptor maturation through facilitating CRX-mediated photoreceptor gene transactivation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8961232/
  24. Mar 2022
  25. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR-Cas9 screening identifies the CYTH2 host gene as a potential therapeutic target of influenza viral infection
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    sciencedirect.com/science/article/pii/S2211124722003035
  26. www.nature.com www.nature.com
    Generation of CRISPR–Cas9-mediated genetic knockout human intestinal tissue–derived enteroid lines by lentivirus transduction and single-cell cloning
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    nature.com/articles/s41596-021-00669-0
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Crry silencing alleviates Alzheimer’s disease injury by regulating neuroinflammatory cytokines and the complement system
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    ncbi.nlm.nih.gov/pmc/articles/PMC8820699/
  28. www.sciencedirect.com www.sciencedirect.com
    Regulation of GTPase function by autophosphorylation
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    sciencedirect.com/science/article/pii/S1097276522001162
  29. elifesciences.org elifesciences.org
    Complex effects of kinase localization revealed by compartment-specific regulation of protein kinase A activity
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    elifesciences.org/articles/66869
  30. Jan 2022
  31. www.sciencedirect.com www.sciencedirect.com
    Functional genetic dropout screens and in vivo validation of candidate therapeutic targets using mouse mammary tumoroids
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    sciencedirect.com/science/article/pii/S2666166722000120
  32. www.nature.com www.nature.com
    Identification of G protein-coupled receptor 55 (GPR55) as a target of curcumin
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    nature.com/articles/s41538-021-00119-x
  33. www.sciencedirect.com www.sciencedirect.com
    R-type voltage-gated Ca2+ channels mediate A-type K+ current regulation of synaptic input in hippocampal dendrites
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    sciencedirect.com/science/article/pii/S2211124721017769
  34. www.sciencedirect.com www.sciencedirect.com
    Genotype-specific features reduce the susceptibility of South American yellow fever virus strains to vaccine-induced antibodies
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    sciencedirect.com/science/article/pii/S1931312821005801
  35. Dec 2021
  36. crc.aacrjournals.org crc.aacrjournals.org
    The ADAM17-directed Inhibitory Antibody MEDI3622 Antagonizes Radiotherapy-induced VEGF Release and Sensitizes Non–Small Cell Lung Cancer for RadiotherapyADAM17-mediated Radioresistance
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    crc.aacrjournals.org/cancerrescommun/article/1/3/164/665523/The-ADAM17-directed-Inhibitory-Antibody-MEDI3622
  37. elifesciences.org elifesciences.org
    Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape
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    elifesciences.org/articles/73027
  38. Nov 2021
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elucidation and refinement of synthetic receptor mechanisms
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    ncbi.nlm.nih.gov/pmc/articles/PMC7759213/
  40. www.sciencedirect.com www.sciencedirect.com
    1-deoxysphingolipids bind to COUP-TF to modulate lymphatic and cardiac cell development
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    sciencedirect.com/science/article/pii/S1534580721008492
  41. Oct 2021
  42. www.sciencedirect.com www.sciencedirect.com
    P5A ATPase controls ER translocation of Wnt in neuronal migration
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    sciencedirect.com/science/article/pii/S2211124721013711
  43. www.jimmunol.org www.jimmunol.org
    JI_proof.pdf
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    jimmunol.org/content/jimmunol/early/2021/05/24/jimmunol.2001235.full.pdf
  44. www.sciencedirect.com www.sciencedirect.com
    Inhibition of HIV infection by structural proteins of the inner nuclear membrane is associated with reduced chromatin dynamics
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    sciencedirect.com/science/article/pii/S2211124721012171
  45. Sep 2021
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SUMOylation of RepoMan during late telophase regulates dephosphorylation of lamin A
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    ncbi.nlm.nih.gov/pmc/articles/PMC8445599/
  47. www.sciencedirect.com www.sciencedirect.com
    Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps
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    sciencedirect.com/science/article/pii/S1097276521007395
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STING nuclear partners contribute to innate immune signaling responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC8436130/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of a High-throughput NanoBRET Screening Platform to Identify Modulators of the RAS/RAF Interaction
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    ncbi.nlm.nih.gov/pmc/articles/PMC8419108/
  50. Aug 2021
  51. elifesciences.org elifesciences.org
    Functional development of a V3/glycan-specific broadly neutralizing antibody isolated from a case of HIV superinfection
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    elifesciences.org/articles/68110
  52. www.sciencedirect.com www.sciencedirect.com
    Loss of tyrosine catabolic enzyme HPD promotes glutamine anaplerosis through mTOR signaling in liver cancer
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    sciencedirect.com/science/article/pii/S221112472101055X
  53. www.sciencedirect.com www.sciencedirect.com
    Responsiveness to perturbations is a hallmark of transcription factors that maintain cell identity in vitro
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    sciencedirect.com/science/article/pii/S2405471221002817
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    High specificity of widely used phospho‐tau antibodies validated using a quantitative whole‐cell based assay
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14830
  55. www.sciencedirect.com www.sciencedirect.com
    Reshaping of the Dendritic Cell Chromatin Landscape and Interferon Pathways during HIV Infection
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    sciencedirect.com/science/article/pii/S1931312818300477
  56. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S2211124719301421
  57. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Phosphorylation of Trans-active response DNA binding protein-of 43 kDa promotes its cytoplasmic aggregation and modulates its function in tau mRNA stability and exon 10 alternative splicing
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15450
  58. www.sciencedirect.com www.sciencedirect.com
    The Ubiquitin-Editing Enzyme A20 Regulates Synapse Remodeling and Efficacy
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    sciencedirect.com/science/article/pii/S0006899319306237
  59. Jul 2021
  60. www.sciencedirect.com www.sciencedirect.com
    Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140
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    sciencedirect.com/science/article/pii/S0896627318308961
  61. www.sciencedirect.com www.sciencedirect.com
    RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss
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    sciencedirect.com/science/article/pii/S2211124718315377
  62. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and Are Targetable by BET Bromodomain Inhibition
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    cancerres.aacrjournals.org/content/79/5/994
  63. elifesciences.org elifesciences.org
    Dissection of the interaction between the intrinsically disordered YAP protein and the transcription factor TEAD
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    elifesciences.org/content/6/e25068
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A microRNA negative feedback loop downregulates vesicle transport and inhibits fear memory
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    ncbi.nlm.nih.gov/pmc/articles/PMC5293492/
  65. portlandpress.com portlandpress.com
    Functional analysis of a species-specific inhibitor selective for human Na+-coupled citrate transporter (NaCT/SLC13A5/mINDY)
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    portlandpress.com/biochemj/article/477/21/4149/226708/Functional-analysis-of-a-species-specific
  66. www.sciencedirect.com www.sciencedirect.com
    An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress
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    sciencedirect.com/science/article/pii/S1097276521004974
  67. Jun 2021
  68. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Mutations in the IFNγ-JAK-STAT pathway causing resistance to immune checkpoint inhibitors in melanoma increase sensitivity to oncolytic virus treatment.
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    clincancerres.aacrjournals.org/content/27/12/3432
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAL GTPases mediate EGFR-driven intestinal stem cell proliferation and tumourigenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8216719/
  70. www.nature.com www.nature.com
    Pericentromeric Satellite III transcripts induce etoposide resistance
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    nature.com/articles/s41419-021-03810-9
  71. May 2021
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2
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    ncbi.nlm.nih.gov/pmc/articles/PMC8106883/
  73. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel functional variants in the Notch pathway and survival of Chinese colorectal cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33561
  74. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Targeting DNA damage repair functions of two histone deacetylases, HDAC8 and SIRT6, sensitizes acute myeloid leukemia to NAMPT inhibition
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    clincancerres.aacrjournals.org/content/27/8/2352
  75. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    HAND1 and BARX1 act as transcriptional and anatomic determinants of malignancy in gastrointestinal stromal tumor
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    clincancerres.aacrjournals.org/content/27/6/1706
  76. www.sciencedirect.com www.sciencedirect.com
    Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas
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    sciencedirect.com/science/article/pii/S1074761320304672
  77. Apr 2021
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine
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    ncbi.nlm.nih.gov/pmc/articles/PMC8122138/
  79. www.sciencedirect.com www.sciencedirect.com
    Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma
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    sciencedirect.com/science/article/pii/S2211124721003272
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    High-Throughput Discovery and Characterization of Human Transcriptional Effectors
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    sciencedirect.com/science/article/pii/S0092867420315415
  81. www.biorxiv.org www.biorxiv.org
    https://biorxiv.org/cgi/content/10.1101/2021.04.08.438911
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    biorxiv.org/content/10.1101/2021.04.08.438911v1
  82. www.sciencedirect.com www.sciencedirect.com
    Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis
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    sciencedirect.com/science/article/pii/S1097276521000988
  83. www.sciencedirect.com www.sciencedirect.com
    Immunogenomic Landscape of Hematological Malignancies
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    sciencedirect.com/science/article/pii/S1535610820302750
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage
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    ncbi.nlm.nih.gov/pmc/articles/PMC8020668/
  85. www.sciencedirect.com www.sciencedirect.com
    DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network
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    sciencedirect.com/science/article/pii/S1097276521002628
  86. Mar 2021
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types
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    ncbi.nlm.nih.gov/pmc/articles/PMC7891930/
  88. Feb 2021
  89. www.pnas.org www.pnas.org
    Human norovirus exhibits strain-specific sensitivity to host interferon pathways in human intestinal enteroids
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    pnas.org/content/117/38/23782
  90. journals.sagepub.com journals.sagepub.com
    A genome-wide CRISPR screen identifies regulation factors of the TLR3 signalling pathway - Laurent Zablocki-Thomas, Sam A Menzies, Paul J Lehner, Nicolas Manel, Philippe Benaroch,
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    journals.sagepub.com/doi/full/10.1177/1753425920915507
  91. elifesciences.org elifesciences.org
    Islet vascularization is regulated by primary endothelial cilia via VEGF-A-dependent signaling
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    elifesciences.org/articles/56914
  92. Dec 2020
  93. www.sciencedirect.com www.sciencedirect.com
    Tracking HIV Rebound following Latency Reversal Using Barcoded HIV
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    sciencedirect.com/science/article/pii/S2666379120302093
  94. www.nature.com www.nature.com
    Generation of neighbor-labeling cells to study intercellular interactions in vivo
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    nature.com/articles/s41596-020-00438-5
  95. Oct 2020
  96. mcr.aacrjournals.org mcr.aacrjournals.org
    NRF2-Driven KEAP1 Transcription in Human Lung Cancer
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    mcr.aacrjournals.org/content/18/10/1465
  97. Sep 2020
  98. www.sciencedirect.com www.sciencedirect.com
    Multiple Signaling Roles of CD3ε and Its Application in CAR-T Cell Therapy
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    sciencedirect.com/science/article/pii/S0092867420308837
  99. elifesciences.org elifesciences.org
    Elongation inhibitors do not prevent the release of puromycylated nascent polypeptide chains from ribosomes
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    elifesciences.org/articles/60048
  100. www.sciencedirect.com www.sciencedirect.com
    CATP-8/P5A ATPase Regulates ER Processing of the DMA-1 Receptor for Dendritic Branching
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    sciencedirect.com/science/article/pii/S2211124720310901
  101. elifesciences.org elifesciences.org
    The orphan receptor GPR88 blunts the signaling of opioid receptors and multiple striatal GPCRs
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    elifesciences.org/articles/50519
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A high-throughput small molecule screen identifies farrerol as a potentiator of CRISPR/Cas9-mediated genome editing
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    ncbi.nlm.nih.gov/pmc/articles/PMC7380943/
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity
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    ncbi.nlm.nih.gov/pmc/articles/PMC7272217/
  104. link.springer.com link.springer.com
    Nucleation and kinetics of SOD1 aggregation in human cells for ALS1
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    link.springer.com/article/10.1007/s11010-020-03693-y
  105. www.sciencedirect.com www.sciencedirect.com
    Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining
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    sciencedirect.com/science/article/pii/S2211124720310536
  106. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma
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    sciencedirect.com/science/article/pii/S1535610820301641
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Replication-Competent Vesicular Stomatitis Virus for Studies of SARS-CoV-2 Spike-Mediated Cell Entry and Its Inhibition
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    ncbi.nlm.nih.gov/pmc/articles/PMC7332447/
  108. www.sciencedirect.com www.sciencedirect.com
    Glioblastoma Cell Resistance to EGFR and MET Inhibition Can Be Overcome via Blockade of FGFR-SPRY2 Bypass Signaling
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