616 Matching Annotations
  1. Jun 2023
  2. www.sciencedirect.com www.sciencedirect.com
    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
    1
    1. scibot 28 Jun 2023
      RRID: IMSR_JAX:005557

      DOI: 10.1016/j.cell.2023.05.047

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    sciencedirect.com/science/article/pii/S0092867423005986
  3. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
    Production of Humanized Mice through Stem Cell Transfer
    1
    1. scibot 24 Jun 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1002/cpz1.800

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    currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cpz1.800
  4. 52.53.155.43 52.53.155.43
    ZIC1 dictates osteogenesis versus adipogenesis in human mesenchymal progenitor cells via a Hedgehog dependent mechanism
    1
    1. scibot 22 Jun 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1093/stmcls/sxad047

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    52.53.155.43/91d5ef3cba61d5494c1cdd0c7353ff90c81b0a5e/sxad047-html.html
  5. www.sciencedirect.com www.sciencedirect.com
    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
    1
    1. scibot 21 Jun 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cmet.2023.05.007

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    sciencedirect.com/science/article/pii/S1550413123001845
  6. www.nature.com www.nature.com
    CNK2 promotes cancer cell motility by mediating ARF6 activation downstream of AXL signalling
    1
    1. scibot 17 Jun 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1038/s41467-023-39281-z

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    nature.com/articles/s41467-023-39281-z
  7. www.biorxiv.org www.biorxiv.org
    RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma
    1
    1. scibot 16 Jun 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1101/2023.06.10.544474

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    biorxiv.org/content/10.1101/2023.06.10.544474v1
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating an Adaptive Immune Response with a Telomerase-mediated Telomere Targeting Therapeutic in Hepatocellular Carcinoma
    1
    1. scibot 03 Jun 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/1535-7163.MCT-23-0039

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    ncbi.nlm.nih.gov/pmc/articles/PMC10233358/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical Efficacy of the Antibody–Drug Conjugate CLDN6–23-ADC for the Treatment of CLDN6-Positive Solid Tumors
    1
    1. scibot 03 Jun 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/1078-0432.CCR-22-2981

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    ncbi.nlm.nih.gov/pmc/articles/PMC10233360/
  10. www.sciencedirect.com www.sciencedirect.com
    Phosphoproteomics guides effective low-dose drug combinations against pancreatic ductal adenocarcinoma
    1
    1. scibot 03 Jun 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2023.112581

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    sciencedirect.com/science/article/pii/S2211124723005922
  11. www.biorxiv.org www.biorxiv.org
    Real Time In vivo Analysis of Pancreatic Beta-cell Autophagic Flux Reveals Impairment Before Onset of Autoimmune Diabetes
    1
    1. scibot 01 Jun 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1101/2023.05.23.541935

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    biorxiv.org/content/10.1101/2023.05.23.541935v1
  12. 52.53.155.43 52.53.155.43
    mct-23-0039-html.html
    1
    1. scibot 01 Jun 2023
      JAX:005557

      DOI: 10.1158/1535-7163.MCT-23-0039

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    52.53.155.43/2e399e27445b3309b8dca3d6b15c5701e7dc6c5e/mct-23-0039-html.html
  13. www.sciencedirect.com www.sciencedirect.com
    Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer
    1
    1. scibot 01 Jun 2023
      RRID:IMSR_JAX:005557Info

      DOI: 10.1016/j.celrep.2023.112533

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    sciencedirect.com/science/article/pii/S2211124723005442
  14. May 2023
  15. www.sciencedirect.com www.sciencedirect.com
    CDKN2A deletion remodels lipid metabolism to prime glioblastoma for ferroptosis
    1
    1. scibot 26 May 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2023.05.001

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    sciencedirect.com/science/article/pii/S153561082300168X
  16. www.sciencedirect.com www.sciencedirect.com
    Enhanced mitochondrial fission inhibits triple-negative breast cancer cell migration through a ROS-dependent mechanism
    1
    1. scibot 26 May 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.isci.2023.106788

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    sciencedirect.com/science/article/pii/S2589004223008659
  17. 52.53.155.43 52.53.155.43
    Intrinsic tumor resistance to CAR T cells is a dynamic transcriptional state that is exploitable with low-dose radiation
    1
    1. scibot 19 May 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1182/bloodadvances.2022009543

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    52.53.155.43/c3edf1bcbe114757202a2e57dfb535e151ecf522/RRID8-html.html
  18. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    A LGR5 reporter pig model closely resembles human intestine for improved study of stem cells in disease
    1
    1. scibot 13 May 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1096/fj.202300223R

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202300223R
  19. www.sciencedirect.com www.sciencedirect.com
    A chimeric antigen receptor uniquely recognizing MICA/B stress proteins provides an effective approach to target solid tumors
    1
    1. scibot 12 May 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.medj.2023.04.004

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    sciencedirect.com/science/article/pii/S2666634023001368
  20. www.embopress.org www.embopress.org
    Oxidative stress enhances the therapeutic action of a respiratory inhibitor in MYC-driven lymphoma
    1
    1. scibot 10 May 2023
      JAX:005557

      DOI: 10.15252/emmm.202216910

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    embopress.org/doi/10.15252/emmm.202216910
  21. www.sciencedirect.com www.sciencedirect.com
    Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal
    1
    1. scibot 05 May 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.stem.2023.04.005

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    sciencedirect.com/science/article/pii/S1934590923001236
  22. www.sciencedirect.com www.sciencedirect.com
    Mast cell tolerance in the skin microenvironment to commensal bacteria is controlled by fibroblasts
    1
    1. scibot 04 May 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2023.112453

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    sciencedirect.com/science/article/pii/S2211124723004643
  23. Apr 2023
  24. www.sciencedirect.com www.sciencedirect.com
    A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression
    1
    1. scibot 29 Apr 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2023.04.002

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    sciencedirect.com/science/article/pii/S1535610823001289
  25. aacrjournals.org aacrjournals.org
    Dual mTORC1/2 inhibition synergistically enhances AML cell death in combination with the BCL2 antagonist venetoclax
    1
    1. scibot 21 Apr 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/1078-0432.CCR-22-2729

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    aacrjournals.org/clincancerres/article/29/7/1332/718764/Dual-mTORC1-2-Inhibition-Synergistically-Enhances
  26. www.sciencedirect.com www.sciencedirect.com
    A kinome-wide CRISPR screen identifies CK1α as a target to overcome enzalutamide resistance of prostate cancer
    1
    1. scibot 19 Apr 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xcrm.2023.101015

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    sciencedirect.com/science/article/pii/S2666379123001258
  27. www.sciencedirect.com www.sciencedirect.com
    Deficiency of the CD155-CD96 immune checkpoint controls IL-9 production in giant cell arteritis
    1
    1. scibot 19 Apr 2023
      JAX:005557

      DOI: 10.1016/j.xcrm.2023.101012

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    sciencedirect.com/science/article/pii/S2666379123001222
  28. www.sciencedirect.com www.sciencedirect.com
    Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis
    1
    1. scibot 19 Apr 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2023.03.002

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    sciencedirect.com/science/article/pii/S1535610823000508
  29. www.sciencedirect.com www.sciencedirect.com
    Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer
    1
    1. scibot 06 Apr 2023
      JAX:005557

      DOI: 10.1016/j.celrep.2023.112324

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    sciencedirect.com/science/article/pii/S2211124723003352
  30. Mar 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination
    1
    1. scibot 28 Mar 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2023.112296

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    sciencedirect.com/science/article/pii/S2211124723003078
  32. www.embopress.org www.embopress.org
    RANK is a poor prognosis marker and a therapeutic target in ER-negative postmenopausal breast cancer
    1
    1. scibot 18 Mar 2023
      RRID:IMSR_JAX:005557

      DOI: 10.15252/emmm.202216715

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    embopress.org/doi/10.15252/emmm.202216715
  33. www.sciencedirect.com www.sciencedirect.com
    Purification and characterization of human neural stem and progenitor cells
    1
    1. scibot 17 Mar 2023
      JAX:005557

      DOI: 10.1016/j.cell.2023.02.017

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    sciencedirect.com/science/article/pii/S0092867423001605
  34. www.science.org www.science.org
    Targeting the chromatin effector Pygo2 promotes cytotoxic T cell responses and overcomes immunotherapy resistance in prostate cancer
    1
    1. scibot 16 Mar 2023
      JAX:005557

      DOI: 10.1126/sciimmunol.ade4656

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    science.org/doi/10.1126/sciimmunol.ade4656
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A tri-specific killer engager against mesothelin targets NK cells towards lung cancer
    1
    1. scibot 16 Mar 2023
      RRID:IMSR_JAX:005557

      DOI: 10.3389/fimmu.2023.1060905

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    ncbi.nlm.nih.gov/pmc/articles/PMC9992642/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    S100A8/S100A9 promote progression of multiple myeloma via expansion of megakaryocytes
    1
    1. scibot 16 Mar 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2767-9764.CRC-22-0368

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    ncbi.nlm.nih.gov/pmc/articles/PMC10010194/
  37. www.sciencedirect.com www.sciencedirect.com
    Source of nicotinamide governs its metabolic fate in cultured cells, mice, and humans
    1
    1. scibot 11 Mar 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2023.112218

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    sciencedirect.com/science/article/pii/S2211124723002292
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Humanized Patient-derived Xenograft Models of Disseminated Ovarian Cancer Recapitulate Key Aspects of the Tumor Immune Environment within the Peritoneal Cavity
    1
    1. scibot 04 Mar 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2767-9764.CRC-22-0300

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    ncbi.nlm.nih.gov/pmc/articles/PMC9973420/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intertumoral Differences Dictate the Outcome of TGF-β Blockade on the Efficacy of Viro-Immunotherapy
    1
    1. scibot 04 Mar 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2767-9764.CRC-23-0019

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    ncbi.nlm.nih.gov/pmc/articles/PMC9973387/
  40. www.sciencedirect.com www.sciencedirect.com
    A bispecific T cell engager recruits both type 1 NKT and Vγ9Vδ2-T cells for the treatment of CD1d-expressing hematological malignancies
    1
    1. scibot 03 Mar 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xcrm.2023.100961

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    sciencedirect.com/science/article/pii/S2666379123000538
  41. www.sciencedirect.com www.sciencedirect.com
    Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer
    1
    1. scibot 03 Mar 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2023.02.004

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    Multiomics reveals glutathione metabolism as a driver of bimodality during stem cell aging
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    Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy
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    Preclinical evaluation of CD70-specific CAR T cells targeting acute myeloid leukemia
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      DOI: 10.3389/fimmu.2023.1093750

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    Genome-Wide Analysis of lncRNA-mRNA Co-Expression Networks in CD133+/CD44+ Stem-like PDAC Cells
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      DOI: 10.3390/cancers15041053

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  46. Feb 2023
  47. www.sciencedirect.com www.sciencedirect.com
    CAR-T cells targeting HLA-G as potent therapeutic strategy for EGFR mutated and overexpressed oral cancer
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    An adverse tumor-protective effect of IDO1 inhibition
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    Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer
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    Post-transplant cyclophosphamide prevents xenogeneic graft-versus-host disease while depleting proliferating regulatory T cells
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  51. 52.53.155.43 52.53.155.43
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  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dysregulated lipid synthesis by oncogenic IDH1 mutation is a targetable synthetic lethal vulnerability
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  53. www.nature.com www.nature.com
    Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy
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      DOI: 10.1038/s41467-022-35583-w

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  54. Jan 2023
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    Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Arginine limitation drives a directed codon-dependent DNA sequence evolution response in colorectal cancer cells
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      DOI: 10.1126/sciadv.ade9120

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    ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis
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      DOI: 10.1126/sciadv.abq3951

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    Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy
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    Genetic screens reveal new targetable vulnerabilities in BAP1-deficient mesothelioma
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    ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis
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  61. www.science.org www.science.org
    Arginine limitation drives a directed codon-dependent DNA sequence evolution response in colorectal cancer cells
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-apoptotic MCL1 Protein Represents Critical Survival Molecule for Most Burkitt Lymphomas and BCL2-negative Diffuse Large B-cell Lymphomas
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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical Efficacy of BCMA-Directed CAR T Cells Incorporating a Novel D Domain Antigen Recognition Domain
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical Development of [211At]meta- astatobenzylguanidine ([211At]MABG) as an Alpha Particle Radiopharmaceutical Therapy for Neuroblastoma
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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel B7-H6–Targeted IgG-Like T Cell–Engaging Antibody for the Treatment of Gastrointestinal Tumors
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    Microbiota-dependent and -independent postnatal development of salivary immunity
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      005557

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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance
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    Human cortical interneurons optimized for grafting specifically integrate, abort seizures, and display prolonged efficacy without over-inhibition
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    A Cdh3-β-catenin-laminin signaling axis in a subset of breast tumor leader cells control leader cell polarization and directional collective migration
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    Synthetic Essentiality of Tryptophan 2,3-dioxygenase 2 in APC-Mutated Colorectal Cancer
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    Endometriosis-associated mesenchymal stem cells support ovarian clear cell carcinoma through iron regulation
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  72. 52.53.155.43 52.53.155.43
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  73. www.mdpi.com www.mdpi.com
    Identification of Genes Associated with Liver Metastasis in Pancreatic Cancer Reveals PCSK6 as a Crucial Mediator
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  74. Dec 2022
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    ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells
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    KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition
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    Expression of inducible factors reprograms CAR-T cells for enhanced function and safety
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    Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells
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    BAF complex maintains glioma stem cells in pediatric H3K27M-glioma
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  81. Nov 2022
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    Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis
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    Estrone, the major postmenopausal estrogen, binds ERa to induce SNAI2, epithelial-to-mesenchymal transition, and ER+ breast cancer metastasis
    1
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      005557

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  84. www.sciencedirect.com www.sciencedirect.com
    Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer
    1
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      RRID:IMSR_JAX:005

      DOI: 10.1016/j.xcrm.2022.100815

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  85. www.science.org www.science.org
    Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies
    2
    1. scibot 12 Nov 2022
      RRID:IMSR_JAX:005557

      DOI: 10.1126/scitranslmed.abm1463

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      RRID:IMSR_JAX:005557

      DOI: 10.1126/scitranslmed.abm1463

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  86. www.sciencedirect.com www.sciencedirect.com
    Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2022.10.009

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  87. www.sciencedirect.com www.sciencedirect.com
    Protocol for evaluating antitumor activity of KIR3DL3 blockade in an NK cell-based xenogeneic lung tumor model
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xpro.2022.101818

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    Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2022.111582

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  89. Oct 2022
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Continuous sensing of IFNα by hepatic endothelial cells shapes a vascular antimetastatic barrier
    1
    1. scibot 27 Oct 2022
      JAX:005557

      DOI: 10.7554/eLife.80690

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    Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation
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      005557

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    PARP-inhibition reprograms macrophages toward an anti-tumor phenotype
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      RRID:IMSR_JAX:005557

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    Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas
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      RRID:IMSR_JAX:005557

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    Targeting telomerase reverse transcriptase with the covalent inhibitor NU-1 confers immunogenic radiation sensitization
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      JAX:005557

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    Validation of a non-oncogene encoded vulnerability to exportin 1 inhibition in pediatric renal tumors
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      RRID:IMSR_JAX

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  96. Sep 2022
  97. www.sciencedirect.com www.sciencedirect.com
    Engineering of immune checkpoints B7-H3 and CD155 enhances immune compatibility of MHC-I−/− iPSCs for β cell replacement
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    1. scibot 29 Sep 2022
      JAX:005557

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    The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2022.111428

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    MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer
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    1. scibot 24 Sep 2022
      005557

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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acute Myeloid Leukemia Alters Group 1 Innate Lymphoid Cell Differentiation from a Common Precursor
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      RRID:IMSR_JAX:005557

      DOI: 10.4049/jimmunol.2100023

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    In vivo bioluminescence imaging of granzyme B activity in tumor response to cancer immunotherapy
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      JAX:005557

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    Targeting histone methylation to reprogram the transcriptional state that drives survival of drug-tolerant myeloid leukemia persisters
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    1. scibot 15 Sep 2022
      RRID:IMSR_JAC:005557

      DOI: 10.1016/j.isci.2022.105013

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    ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes
    1
    1. scibot 08 Sep 2022
      Mouse: NSG NOD/ShiLtJ

      DOI: 10.1016/j.cmet.2022.08.007

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  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
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      RRID:IMSR_JAX:005557

      DOI: 10.1158/2159-8290.CD-21-1077

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  105. Aug 2022
  106. www.sciencedirect.com www.sciencedirect.com
    Vitamin D receptor activation is a feasible therapeutic target to impair adrenocortical tumorigenesis
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      JAX_005557

      DOI: 10.1016/j.mce.2022.111757

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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ARID1A-deficient bladder cancer is dependent on PI3K signaling and sensitive to EZH2 and PI3K inhibitors
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      RRID:IMSR_JAX:005557

      DOI: 10.1172/jci.insight.155899

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    A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma
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      RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1535610822003257
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    Off-The-Shelf Third-Party HSC-Engineered iNKT Cells for Ameliorating GvHD While Preserving GvL Effect in the Treatment of Blood Cancers
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      The Jackson LaboratoryStock #: 005557

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    sciencedirect.com/science/article/pii/S2589004222011312
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    EZH2 T367 phosphorylation activates p38 signaling through lysine methylation to promote breast cancer progression
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      Jackson LaboratoryCat #005557

      DOI: 10.1016/j.isci.2022.104827

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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BCL10 mutations define distinct dependencies guiding precision therapy for DLBCL
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      RRID:IMSR_JAX

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    EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity
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      Jackson LaboratoriesCat# 005557

      DOI: 10.1016/j.stem.2022.06.014

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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells
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      RRID:IMSR_JAX:005557

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    Co-targeting of specific epigenetic regulators in combination with CDC7 potently inhibit melanoma growth
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      Jackson LaboratoryStock No. 005557

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  115. Jul 2022
  116. www.sciencedirect.com www.sciencedirect.com
    High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibition
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      The Jackson Laboratory005557

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  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EGFR inhibition enhances the cellular uptake and antitumor-activity of the HER3 antibody drug conjugate HER3-DXd
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      RRID:IMSR_JAX:005557

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  118. Jun 2022
  119. 52.53.155.43 52.53.155.43
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    1. scibot 30 Jun 2022
      RRID:IMSR_JAX:005557

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    Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence
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      JAX:005557

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    Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma
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      Jackson LaboratoryStock# 005557

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    Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas
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      JacksonCat#005557

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    Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge
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      The Jackson LaboratoryStock No: 005557

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    Oncofusion-driven de novo enhancer assembly promotes malignancy in Ewing sarcoma via aberrant expression of the stereociliary protein LOXHD1
    1
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      Jackson Laboratory005557

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  125. aacrjournals.org aacrjournals.org
    Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1158/2767-9764.CRC-22-0124

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    aacrjournals.org/cancerrescommun/article/2/6/402/699311/Cancer-Stem-Cells-not-Bulk-Tumor-Cells-Determine
  126. www.sciencedirect.com www.sciencedirect.com
    Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids
    1
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      The Jackson LaboratoryStrain #005557

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  127. www.sciencedirect.com www.sciencedirect.com
    A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of its bound metabolic mRNAs
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.molcel.2022.05.008

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    sciencedirect.com/science/article/pii/S1097276522004427
  128. May 2022
  129. www.sciencedirect.com www.sciencedirect.com
    Therapeutic development for Canavan disease using patient iPSCs introduced with the wild-type ASPA gene
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      Jackson Laboratory005557

      DOI: 10.1016/j.isci.2022.104391

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    sciencedirect.com/science/article/pii/S2589004222006629
  130. www.sciencedirect.com www.sciencedirect.com
    Homogeneity of antibody-drug conjugates critically impacts the therapeutic efficacy in brain tumors
    1
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      The Jackson LaboratoryCat#005557

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  131. www.sciencedirect.com www.sciencedirect.com
    ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1
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      The Jackson Laboratory005557

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  132. www.sciencedirect.com www.sciencedirect.com
    c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity
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      Jackson Laboratory005557

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  133. www.sciencedirect.com www.sciencedirect.com
    WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC
    1
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      JACKSON LABORATORYStock #: 005557

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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Matricellular protein WISP2 is an endogenous inhibitor of collagen linearization and cancer metastasis
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1158/0008-5472.CAN-20-3982

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  135. www.sciencedirect.com www.sciencedirect.com
    Fasting induces a highly resilient deep quiescent state in muscle stem cells via ketone body signaling
    1
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      RRID:IMSR_JAX:005557

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    Lymph node colonization induces tumor-immune tolerance to promote distant metastasis
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      Jackson Laboratories#005557

      DOI: 10.1016/j.cell.2022.04.019

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    sciencedirect.com/science/article/pii/S0092867422004664
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    Antigen presentation safeguards the integrity of the hematopoietic stem cell pool
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      JAX:005557

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    sciencedirect.com/science/article/pii/S1934590922001606
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    Patient-derived models of brain metastases recapitulate human disseminated disease
    1
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      RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S2666379122001409
  139. Apr 2022
  140. www.sciencedirect.com www.sciencedirect.com
    Functional genetic screen identifies ITPR3/calcium/RELB axis as a driver of colorectal cancer metastatic liver colonization
    1
    1. scibot 29 Apr 2022
      The Jackson LaboratoryStrain: 005557

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  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SynNotch CAR Circuits Enhance Solid Tumor Recognition and Promote Persistent Anti-tumor Activity in Mouse Models
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1126/scitranslmed.abd8836

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    The myogenesis program drives clonal selection and drug resistance in rhabdomyosarcoma
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      Jackson Laboratoriesstrain 005557

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    sciencedirect.com/science/article/pii/S153458072200243X
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    Enhanced safety and efficacy of protease-regulated CAR-T cell receptors
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      Jackson Laboratory005557

      DOI: 10.1016/j.cell.2022.03.041

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    sciencedirect.com/science/article/pii/S0092867422003919
  144. www.science.org www.science.org
    SynNotch CAR circuits enhance solid tumor recognition and promote persistent antitumor activity in mouse models
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1126/scitranslmed.abd8836

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    The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes
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      Jackson Laboratory005557

      DOI: 10.1016/j.stem.2022.03.015

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    sciencedirect.com/science/article/pii/S1934590922001503
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    The mitochondrial pyruvate carrier regulates memory T cell differentiation and antitumor function
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      Jackson LaboratoryJax: 005557

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    sciencedirect.com/science/article/pii/S1550413122001279
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    Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2022.04.001

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    sciencedirect.com/science/article/pii/S153561082200157X
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    Quiescent cancer cells resist T cell attack by forming an immunosuppressive niche
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      The Jackson LaboratoryStrain #:005557

      DOI: 10.1016/j.cell.2022.03.033

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    sciencedirect.com/science/article/pii/S0092867422003439
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    Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis
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      RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S0092867422003403
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    Modular design of synthetic receptors for programmed gene regulation in cell therapies
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    1. scibot 20 Apr 2022
      Jackson LaboratoriesCat#005557

      DOI: 10.1016/j.cell.2022.03.023

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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multilayered control of splicing regulatory networks by DAP3 leads to widespread alternative splicing changes in cancer
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      RRID:IMSR_JAX:005557

      DOI: 10.1038/s41467-022-29400-7

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    Human pluripotent stem cell-derived myogenic progenitors undergo maturation to quiescent satellite cells upon engraftment
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      RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1934590922001023
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    Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer
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      Jackson#005557

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    sciencedirect.com/science/article/pii/S221112472200393X
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    Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma
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      Jackson LaboratoriesCat# 005557

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    sciencedirect.com/science/article/pii/S2211124722003898
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    Therapeutic correction of hemophilia A by transplantation of hPSC-derived liver sinusoidal endothelial cell progenitors
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      The Jackson Laboratory; OCI colonyCat#005557

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    sciencedirect.com/science/article/pii/S2211124722003692
  156. aacrjournals.org aacrjournals.org
    mDKN-01, a Novel Anti-DKK1 mAb, Enhances Innate Immune Responses in the Tumor Microenvironment
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      RRID:IMSR_JAX:005557

      DOI: 10.1158/1541-7786.MCR-20-0799

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    aacrjournals.org/mcr/article/19/4/717/672854/mDKN-01-a-Novel-Anti-DKK1-mAb-Enhances-Innate
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    Melanomas with concurrent BRAF non-p.V600 and NF1 loss-of-function mutations are targetable by BRAF/MEK inhibitor combination therapy
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      RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005

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    sciencedirect.com/science/article/pii/S2211124722003862
  158. aacrjournals.org aacrjournals.org
    Subversion of serotonin-receptor signaling in osteoblasts by kynurenine drives Acute Myeloid Leukemia
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      RRID:IMSR_JAX:005557

      DOI: 10.1158/2159-8290.CD-21-0692

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    aacrjournals.org/cancerdiscovery/article/12/4/1106/689604/Subversion-of-Serotonin-Receptor-Signaling-in
  159. Mar 2022
  160. www.nature.com www.nature.com
    ADARs act as potent regulators of circular transcriptome in cancer
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      RRID:IMSR_JAX:005557

      DOI: 10.1038/s41467-022-29138-2

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  161. www.sciencedirect.com www.sciencedirect.com
    A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy
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      Jackson LaboratoryStock No: 005557

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    sciencedirect.com/science/article/pii/S1550413122000535
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    Lamin B1 deletion in myeloid neoplasms causes nuclear anomaly and altered hematopoietic stem cell function
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      Jackson labscat#: 005557

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    3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T cells
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      Jackson LaboratoryStrain #005557

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    Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML
    1
    1. scibot 09 Mar 2022
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2022.110481

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    Tumor-derived Jagged1 promotes cancer progression through immune evasion
    1
    1. scibot 09 Mar 2022
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2022.110492

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  166. www.sciencedirect.com www.sciencedirect.com
    CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4
    1
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      JAX:005557

      DOI: 10.1016/j.ccell.2022.02.003

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  167. Feb 2022
  168. www.sciencedirect.com www.sciencedirect.com
    A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells
    1
    1. scibot 23 Feb 2022
      Jackson LaboratoryCat# 005557

      DOI: 10.1016/j.molcel.2022.01.022

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  169. www.sciencedirect.com www.sciencedirect.com
    Balanced T and B cell responses are required for immune protection against Powassan virus in virus-like particle vaccination
    1
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      The Jackson Laboratory005557

      DOI: 10.1016/j.celrep.2022.110388

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  170. www.sciencedirect.com www.sciencedirect.com
    Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth
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      RRID:IMSR_JAX

      DOI: 10.1016/j.medj.2021.12.008

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  171. www.sciencedirect.com www.sciencedirect.com
    Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants
    2
    1. scibot 11 Feb 2022
      005557

      DOI: 10.1016/j.celrep.2022.110322

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      005557

      DOI: 10.1016/j.celrep.2022.110322

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  172. link.springer.com link.springer.com
    When left does not seem right: epigenetic and bioelectric differences between left- and right-sided breast cancer
    1
    1. scibot 08 Feb 2022
      RRID:IMSR_JAX:005557

      DOI: 10.1186/s10020-022-00440-5

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  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Steroid hormone receptor and infiltrating immune cell status reveals therapeutic vulnerabilities of ESR1 mutant breast cancer.
    1
    1. scibot 02 Feb 2022
      RRID:IMSR_JAX:005557

      DOI: 10.1158/0008-5472.CAN-20-1200

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  174. Jan 2022
  175. www.sciencedirect.com www.sciencedirect.com
    Regulation of reverse electron transfer at mitochondrial complex I by unconventional Notch action in cancer stem cells
    1
    1. scibot 27 Jan 2022
      #005557

      DOI: 10.1016/j.devcel.2021.12.020

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  176. www.sciencedirect.com www.sciencedirect.com
    Autologous humanized mouse models of iPSC-derived tumors enable characterization and modulation of cancer-immune cell interactions
    1
    1. scibot 16 Jan 2022
      The Jackson LaboratoryCat# 005557

      DOI: 10.1016/j.crmeth.2021.100153

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  177. www.sciencedirect.com www.sciencedirect.com
    SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia
    1
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      The Jackson LaboratoryStock No: 005557

      DOI: 10.1016/j.celrep.2021.110233

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  178. www.sciencedirect.com www.sciencedirect.com
    Metabolic diversity within breast cancer brain-tropic cells determines metastatic fitness
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    1. scibot 05 Jan 2022
      Cat#005557

      DOI: 10.1016/j.cmet.2021.12.001

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    sciencedirect.com/science/article/pii/S1550413121006203
  179. Dec 2021
  180. www.sciencedirect.com www.sciencedirect.com
    GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity
    1
    1. scibot 31 Dec 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2021.12.005

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  181. www.sciencedirect.com www.sciencedirect.com
    EMSY inhibits homologous recombination repair and the interferon response, promoting lung cancer immune evasion
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    1. scibot 28 Dec 2021
      Stock No. 005557

      DOI: 10.1016/j.cell.2021.12.005

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  182. www.sciencedirect.com www.sciencedirect.com
    An NK-like CAR T cell transition in CAR T cell dysfunction
    1
    1. scibot 03 Dec 2021
      Cat# 5557

      DOI: 10.1016/j.cell.2021.11.016

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  183. www.nature.com www.nature.com
    Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer
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      RRID:IMSR_JAX:005557

      DOI: 10.1038/s42003-021-02842-3

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  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of EGFR-mutant lung cancer
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    1. scibot 01 Dec 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1126/scitranslmed.abb3738

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    ncbi.nlm.nih.gov/pmc/articles/PMC8627689/
  185. Nov 2021
  186. www.sciencedirect.com www.sciencedirect.com
    Immuno-transcriptomic profiling of extracranial pediatric solid malignancies
    1
    1. scibot 30 Nov 2021
      Stock No: 005557

      DOI: 10.1016/j.celrep.2021.110047

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    sciencedirect.com/science/article/pii/S2211124721015333
  187. www.sciencedirect.com www.sciencedirect.com
    Distinct contributions of partial and full EMT to breast cancer malignancy
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    1. scibot 30 Nov 2021
      JAX:005557

      DOI: 10.1016/j.devcel.2021.11.006

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    Protein kinase Cι and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities
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    1. scibot 24 Nov 2021
      Stock# 005557

      DOI: 10.1016/j.celrep.2021.110054

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  189. www.sciencedirect.com www.sciencedirect.com
    Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis
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      005557

      DOI: 10.1016/j.celrep.2021.110056

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    Effective chimeric antigen receptor T-cells (CAR-Ts) against SARS-CoV-2
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    1. scibot 18 Nov 2021
      005557

      DOI: 10.1016/j.isci.2021.103295

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    sciencedirect.com/science/article/pii/S2589004221012645
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    Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy
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      Stock #: 005557

      DOI: 10.1016/j.xcrm.2021.100449

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    sciencedirect.com/science/article/pii/S2666379121003177
  192. www.sciencedirect.com www.sciencedirect.com
    A patch of positively charged residues regulates the efficacy of clinical DR5 antibodies in solid tumors
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    1. scibot 09 Nov 2021
      005557

      DOI: 10.1016/j.celrep.2021.109953

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  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells
    1
    1. scibot 05 Nov 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ebiom.2021.103646

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    ncbi.nlm.nih.gov/pmc/articles/PMC8546421/
  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies
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    1. scibot 05 Nov 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2159-8290.CD-20-1243

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    ncbi.nlm.nih.gov/pmc/articles/PMC8406797/
  195. Oct 2021
  196. www.sciencedirect.com www.sciencedirect.com
    Enteric pathogens induce tissue tolerance and prevent neuronal loss from subsequent infections
    1
    1. scibot 30 Oct 2021
      005557

      DOI: 10.1016/j.cell.2021.10.004

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    Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis
    1
    1. scibot 21 Oct 2021
      005557

      DOI: 10.1016/j.celrep.2021.109870

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  198. www.sciencedirect.com www.sciencedirect.com
    Marker-free lineage tracing reveals an environment-instructed clonogenic hierarchy in pancreatic cancer
    1
    1. scibot 21 Oct 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2021.109852

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  199. www.sciencedirect.com www.sciencedirect.com
    Pan-cancer analysis of non-coding transcripts reveals the prognostic onco-lncRNA HOXA10-AS in gliomas
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    1. scibot 21 Oct 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2021.109873

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  200. www.science.org www.science.org
    Therapeutic targeting of SLC6A8 creatine transporter suppresses colon cancer progression and modulates human creatine levels
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    1. scibot 18 Oct 2021
      005557

      DOI: 10.1126/sciadv.abi7511

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    science.org/doi/abs/10.1126/sciadv.abi7511
  201. www.science.org www.science.org
    Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of EGFR-mutant lung cancer
    1
    1. scibot 18 Oct 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1126/scitranslmed.abb3738

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  202. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic targeting of SLC6A8 creatine transporter suppresses colon cancer progression and modulates human creatine levels
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    1. scibot 15 Oct 2021
      JAX stock #005557

      DOI: 10.1126/sciadv.abi7511

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    Tracing the emergence of primordial germ cells from bilaminar disc rabbit embryos and pluripotent stem cells
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      005557

      DOI: 10.1016/j.celrep.2021.109812

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  204. Sep 2021
  205. www.sciencedirect.com www.sciencedirect.com
    NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis
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    1. scibot 23 Sep 2021
      Strain# 005557

      DOI: 10.1016/j.molcel.2021.08.034

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    Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging
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      Stock# 005557

      DOI: 10.1016/j.celrep.2021.109689

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    Synergistic PIM kinase and proteasome inhibition as a therapeutic strategy for MYC-overexpressing triple-negative breast cancer
    1
    1. scibot 15 Sep 2021
      005,557

      DOI: 10.1016/j.chembiol.2021.08.011

      Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)

      Curator: @Naa003

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRIDCUR:Missing RRID:IMSR_JAX:005557
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    sciencedirect.com/science/article/pii/S2451945621004001
  208. www.sciencedirect.com www.sciencedirect.com
    Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy
    1
    1. scibot 15 Sep 2021
      JAX:005557

      DOI: 10.1016/j.stem.2021.08.013

      Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557
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    sciencedirect.com/science/article/pii/S1934590921003507
  209. www.sciencedirect.com www.sciencedirect.com
    Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor
    1
    1. scibot 14 Sep 2021
      005557

      DOI: 10.1016/j.ccell.2021.08.009

      Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)

      Curator: @Naa003

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1535610821004499
  210. Aug 2021
  211. www.sciencedirect.com www.sciencedirect.com
    Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors
    1
    1. scibot 25 Aug 2021
      JAX:005557

      DOI: 10.1016/j.celrep.2021.109568

      Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557
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    sciencedirect.com/science/article/pii/S2211124721010020
  212. www.sciencedirect.com www.sciencedirect.com
    Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection
    1
    1. scibot 18 Aug 2021
      Stock No: 005557

      DOI: 10.1016/j.celrep.2021.109538

      Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)

      Curator: @Naa003

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S2211124721009724
  213. www.sciencedirect.com www.sciencedirect.com
    Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis
    1
    1. scibot 16 Aug 2021
      JAX:005557

      DOI: 10.1016/j.ccell.2021.07.006

      Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557
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    sciencedirect.com/science/article/pii/S1535610821003834
  214. www.sciencedirect.com www.sciencedirect.com
    Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy
    1
    1. scibot 16 Aug 2021
      JAX:005557

      DOI: 10.1016/j.cell.2021.07.020

      Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557
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    sciencedirect.com/science/article/pii/S0092867421008795
  215. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells
    1
    1. scibot 15 Aug 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2159-8290.CD-20-0331

      Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557
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    ncbi.nlm.nih.gov/pmc/articles/PMC8110214/
  216. www.sciencedirect.com www.sciencedirect.com
    Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia
    1
    1. scibot 14 Aug 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2019.06.003

      Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557
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    sciencedirect.com/science/article/pii/S1535610819302946
  217. www.sciencedirect.com www.sciencedirect.com
    Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression
    1
    1. scibot 11 Aug 2021
      JAX:005557

      DOI: 10.1016/j.stem.2016.12.001

      Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557
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    sciencedirect.com/science/article/pii/S193459091630457X
  218. www.sciencedirect.com www.sciencedirect.com
    ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency
    1
    1. scibot 07 Aug 2021
      Stock No: 005557

      DOI: 10.1016/j.molcel.2021.07.018

      Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)

      Curator: @Naa003

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1097276521005876
  219. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic regulation of mammalian Hedgehog signaling to the stroma determines the molecular subtype of bladder cancer
    1
    1. scibot 06 Aug 2021
      RRID:IMSR_JAX:005557

      DOI: 10.7554/eLife.43024

      Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557
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    ncbi.nlm.nih.gov/pmc/articles/PMC6597241/