798 Matching Annotations
  1. Sep 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRMT5 supports multiple oncogenic pathways in mantle cell lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10517215/
  3. aacrjournals.org aacrjournals.org
    Aberrant L-Fucose accumulation and increased core fucosylation are metabolic liabilities in mesenchymal glioblastoma
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    aacrjournals.org/cancerres/article/83/2/195/715074/Aberrant-L-Fucose-Accumulation-and-Increased-Core
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bifunctional inhibitor reveals NEK2 as a therapeutic target and regulator of oncogenic pathways in lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10932871/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting AKR1B10 by drug repurposing with epalrestat overcomes chemoresistance in non-small cell lung cancer patient-derived tumor organoids
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369614/
  6. www.sciencedirect.com www.sciencedirect.com
    A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib
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    sciencedirect.com/science/article/pii/S2666379124004245
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    Smarcd1 subunit of SWI/SNF chromatin-remodeling complexes collaborates with E2a to promote murine lymphoid specification
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    sciencedirect.com/science/article/pii/S1534580724004908
  8. Aug 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of Forkhead Box P3 in Interferon γ-mediated PD-L1 Expression and Bladder Cancer Epithelial-to-Mesenchymal Transition
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    ncbi.nlm.nih.gov/pmc/articles/PMC11345674/
  10. www.cell.com www.cell.com
    Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies
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    cell.com/cell/fulltext/S0092-8674(20)30163-X
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    Interleukin-21 engineering enhances NK cell activity against glioblastoma via CEBPD
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    sciencedirect.com/science/article/pii/S1535610824002721
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    Nuclear PKM2 binds pre-mRNA at folded G-quadruplexes and reveals their gene regulatory role
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    sciencedirect.com/science/article/pii/S1097276524006233
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-EGFR Antibody–Drug Conjugate Carrying an Inhibitor Targeting CDK Restricts Triple-Negative Breast Cancer Growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292198/
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    Time- and cell-specific activation of BMP signaling restrains chondrocyte hypertrophy
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    sciencedirect.com/science/article/pii/S2589004224017620
  15. www.biorxiv.org www.biorxiv.org
    Senescent fibroblasts in the tumor stroma rewire lung cancer metabolism and plasticity
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    biorxiv.org/content/10.1101/2024.07.29.605645v1
  16. www.nature.com www.nature.com
    A humanized mouse that mounts mature class-switched, hypermutated and neutralizing antibody responses
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    nature.com/articles/s41590-024-01880-3
  17. cancerci.biomedcentral.com cancerci.biomedcentral.com
    Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer
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    cancerci.biomedcentral.com/articles/10.1186/s12935-024-03231-6
  18. www.biorxiv.org www.biorxiv.org
    Salmonella enterica serovar Typhi uses two type 3 secretion systems to replicate in human macrophages and to colonize humanized mice
    1
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    biorxiv.org/content/10.1101/2023.06.06.543980v1
  19. Jul 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-Myristoyltransferase Inhibition causes Mitochondrial Iron Overload and Parthanatos in TIM17A-dependent Aggressive Lung Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11270646/
  21. www.sciencedirect.com www.sciencedirect.com
    Protocol for assessing GD2 on formalin-fixed paraffin-embedded tissue sections using immunofluorescence staining
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    sciencedirect.com/science/article/pii/S2666166724003642
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    Integrated transcriptomics of human blood vessels defines a spatially controlled niche for early mesenchymal progenitor cells
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    sciencedirect.com/science/article/pii/S1534580724003939
  23. www.sciencedirect.com www.sciencedirect.com
    PAI-1 uncouples integrin-β1 from restrain by membrane-bound β-catenin to promote collagen fibril remodeling in obesity-related neoplasms
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    sciencedirect.com/science/article/pii/S2211124724008568
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    Targeting the mSWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies
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    sciencedirect.com/science/article/pii/S1535610824002319
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    Preclinical proof of principle for orally delivered Th17 antagonist miniproteins
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    sciencedirect.com/science/article/pii/S0092867424006317
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    Protocol to construct humanized mice with adult CD34+ hematopoietic stem and progenitor cells
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    sciencedirect.com/science/article/pii/S2666166724003204
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11293342/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRDM6 promotes medulloblastoma by repressing chromatin accessibility and altering gene expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11239875/
  29. www.biorxiv.org www.biorxiv.org
    Organoid Models Derived from Primary Tumors and Patient-Derive Xenograft Tumors Reflect Platinum Sensitivity of Ovarian Cancer Patients
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    biorxiv.org/content/10.1101/2024.06.28.601283v1
  30. www.cell.com www.cell.com
    Elevating PLK1 overcomes BETi resistance in prostate cancer via triggering BRD4 phosphorylation-dependent degradation in mitosis
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    cell.com/cell-reports/fulltext/S2211-1247(24)00760-5
  31. www.mdpi.com www.mdpi.com
    HER4 Affects Sensitivity to Tamoxifen and Abemaciclib in Luminal Breast Cancer Cells and Restricts Tumor Growth in MCF-7-Based Humanized Tumor Mice
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    mdpi.com/1422-0067/25/13/7475
  32. www.cell.com www.cell.com
    Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies
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    cell.com/cell-stem-cell/abstract/S1934-5909(24)00219-4
  33. Jun 2024
  34. www.nature.com www.nature.com
    A humanized mouse that mounts mature class-switched, hypermutated and neutralizing antibody responses
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    nature.com/articles/s41590-024-01880-3
  35. www.sciencedirect.com www.sciencedirect.com
    TNF-NF-κB-p53 axis restricts in vivo survival of hPSC-derived dopamine neurons
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    sciencedirect.com/science/article/pii/S0092867424005750
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11175596/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The exonuclease TREX1 constitutes an innate immune checkpoint limiting cGAS/STING-mediated antitumor immunity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11148535/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nextflow pipeline for Visium and H&E data from patient-derived xenograft samples
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    ncbi.nlm.nih.gov/pmc/articles/PMC11133696/
  39. www.sciencedirect.com www.sciencedirect.com
    De novo and salvage purine synthesis pathways across tissues and tumors
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    sciencedirect.com/science/article/pii/S0092867424005208
  40. www.cell.com www.cell.com
    DARPin-fused T cell engager for adenovirus-mediated cancer therapy
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    cell.com/molecular-therapy-family/oncology/abstract/S2950-3299(24)00063-8
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancing PKA-dependent mesothelial barrier integrity reduces ovarian cancer spheroid transmesothelial migration via inhibition of contractility
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    ncbi.nlm.nih.gov/pmc/articles/PMC11134878/
  42. May 2024
  43. www.sciencedirect.com www.sciencedirect.com
    Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
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    sciencedirect.com/science/article/pii/S1535610824001697
  44. www.biorxiv.org www.biorxiv.org
    SMAD4 and KRAS status shape malignant-stromal crosstalk in pancreatic cancer
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    biorxiv.org/content/10.1101/2024.04.28.591518v1
  45. aacrjournals.org aacrjournals.org
    Development of chromosome 1q+ specific treatment for highest risk pediatric posterior fossa ependymoma
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    aacrjournals.org/clincancerres/article/30/8/1544/742119/Development-of-Chromosome-1q-Specific-Treatment
  46. 52.53.155.43 52.53.155.43
    cir-23-1078-html.html
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    52.53.155.43/ee0bd7762d373e957152429ed1d9032329c895e5/cir-23-1078-html.html
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An imbalance between proliferation and differentiation underlies the development of microRNA-defective pineoblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11071395/
  48. www.sciencedirect.com www.sciencedirect.com
    linc-ADAIN, a human adipose lincRNA, regulates adipogenesis by modulating KLF5 and IL-8 mRNA stability
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    sciencedirect.com/science/article/pii/S2211124724005680
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neoadjuvant radiotherapy in ER+, HER2+, and triple-negative -specific breast cancer based humanized tumor mice enhances anti-PD-L1 treatment efficacy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11089195/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human CD4+ Memory Phenotype T cells use mitochondrial metabolism to generate sensitive IFN-γ responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC11079467/
  51. www.sciencedirect.com www.sciencedirect.com
    Inhibition of protein translational machinery in triple-negative breast cancer as a promising therapeutic strategy
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    sciencedirect.com/science/article/pii/S2666379124002441
  52. www.sciencedirect.com www.sciencedirect.com
    Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma
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    sciencedirect.com/science/article/pii/S2211124724005394
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Urolithin-A Promotes CD8+ T Cell–mediated Cancer Immunosurveillance via FOXO1 Activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11067828/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Transcriptomic Analysis of EWSR1::WT1 Targets Identifies CDK4/6 Inhibitors as an Effective Therapy for Desmoplastic Small Round Cell Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11063761/
  55. www.biorxiv.org www.biorxiv.org
    Imipridones inhibit tumor growth and improve survival in an orthotopic liver metastasis mouse model of human uveal melanoma
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    biorxiv.org/content/10.1101/2024.01.12.575058v1
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical Multi-Omic Assessment of Pioglitazone in Skeletal Muscles of Mice Implanted with Human HER2/neu Overexpressing Breast Cancer Xenografts
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    ncbi.nlm.nih.gov/pmc/articles/PMC11042380/
  57. www.sciencedirect.com www.sciencedirect.com
    Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas
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    sciencedirect.com/science/article/pii/S1535610824001314
  58. Apr 2024
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vitro platform to model the function of ionocytes in the human airway epithelium
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    ncbi.nlm.nih.gov/pmc/articles/PMC11045446/
  60. www.sciencedirect.com www.sciencedirect.com
    Selective refueling of CAR T cells using ADA1 and CD26 boosts antitumor immunity
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    sciencedirect.com/science/article/pii/S266637912400199X
  61. www.sciencedirect.com www.sciencedirect.com
    Development of a chimeric cytokine receptor that captures IL-6 and enhances the antitumor response of CAR-T cells
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    sciencedirect.com/science/article/pii/S2666379124001952
  62. www.sciencedirect.com www.sciencedirect.com
    Human anti-PSCA CAR macrophages possess potent antitumor activity against pancreatic cancer
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    sciencedirect.com/science/article/pii/S1934590924001243
  63. www.pnas.org www.pnas.org
    NOVA1 acts as an oncogenic RNA-binding protein to regulate cholesterol homeostasis in human glioblastoma cells
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    pnas.org/doi/abs/10.1073/pnas.2314695121
  64. link.springer.com link.springer.com
    Single-cell analysis reveals context-dependent, cell-level selection of mtDNA
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    link.springer.com/article/10.1038/s41586-024-07332-0
  65. www.liebertpub.com www.liebertpub.com
    Biodistribution and Safety of Human Multi-Chimeric Cells (HMCC) After Systemic Intraosseous and Intravenous Administration in the Experimental Mouse Model
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    liebertpub.com/doi/10.1089/scd.2024.0007
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
  67. www.sciencedirect.com www.sciencedirect.com
    Differential RNA Expression Between Metastatic and Primary Neuroblastoma Cells
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    sciencedirect.com/science/article/pii/S0022480424001434
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Memory-like differentiation, tumor targeting monoclonal antibodies, and chimeric antigen receptors enhance natural killer cell responses to head and neck cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10796148/
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    iPSC-based modeling of preeclampsia identifies epigenetic defects in extravillous trophoblast differentiation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11016801/
  70. www.sciencedirect.com www.sciencedirect.com
    Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons
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    sciencedirect.com/science/article/pii/S1934590924000948
  71. www.sciencedirect.com www.sciencedirect.com
    Pharmacological induction of chromatin remodeling drives chemosensitization in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2666379124001733
  72. www.sciencedirect.com www.sciencedirect.com
    Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer
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    sciencedirect.com/science/article/pii/S2211124724003693
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983107/
  74. www.nature.com www.nature.com
    Targeting branched N-glycans and fucosylation sensitizes ovarian tumors to immune checkpoint blockade
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    nature.com/articles/s41467-024-47069-y
  75. www.sciencedirect.com www.sciencedirect.com
    Targeting DNMT3A-mediated oxidative phosphorylation to overcome ibrutinib resistance in mantle cell lymphoma
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    sciencedirect.com/science/article/pii/S2666379124001307
  76. Mar 2024
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MARCH2, a novel oncogene-regulated SNAIL E3 ligase, suppresses triple negative breast cancer metastases
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    ncbi.nlm.nih.gov/pmc/articles/PMC10977041/
  78. www.sciencedirect.com www.sciencedirect.com
    Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma
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    sciencedirect.com/science/article/pii/S2666379124001149
  79. www.sciencedirect.com www.sciencedirect.com
    Multiparatopic antibodies induce targeted downregulation of programmed death-ligand 1
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    sciencedirect.com/science/article/pii/S2451945624000886
  80. www.nature.com www.nature.com
    Regulatory T cells expressing CD19-targeted chimeric antigen receptor restore homeostasis in Systemic Lupus Erythematosus
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    nature.com/articles/s41467-024-46448-9
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drug-resistant EGFR mutations promote lung cancer by stabilizing interfaces in ligand-free kinase-active EGFR oligomers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10951324/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The bone ecosystem facilitates multiple myeloma relapse and the evolution of heterogeneous drug resistant disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC10951361/
  83. www.sciencedirect.com www.sciencedirect.com
    FAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis
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    sciencedirect.com/science/article/pii/S1097276524001801
  84. www.pnas.org www.pnas.org
    CD73 contributes to the pathogenesis of fusion-negative rhabdomyosarcoma through the purinergic signaling pathway
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    pnas.org/doi/abs/10.1073/pnas.2315925121
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing associated with therapeutic response to splicing inhibitor
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    ncbi.nlm.nih.gov/pmc/articles/PMC10942784/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Precision Enhancement of CAR-NK Cells through Non-Viral Engineering and Highly Multiplexed Base Editing
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    ncbi.nlm.nih.gov/pmc/articles/PMC10942345/
  87. www.sciencedirect.com www.sciencedirect.com
    ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis
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    sciencedirect.com/science/article/pii/S1535610824000540
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ALK upregulates POSTN and WNT signaling to drive neuroblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11101011/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutralizing antibodies impair the oncolytic efficacy of reovirus but permit effective combination with T cell-based immunotherapies
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    ncbi.nlm.nih.gov/pmc/articles/PMC10911706/
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engraftment of adult hematopoietic stem and progenitor cells in a novel model of humanized mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10904995/
  91. www.sciencedirect.com www.sciencedirect.com
    Identification and characterization of a potent and selective HUNK inhibitor for treatment of HER2+ breast cancer
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    sciencedirect.com/science/article/pii/S2451945624000370
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10897411/
  93. 52.53.155.43 52.53.155.43
    FEBS Press
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  94. Feb 2024
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