261 Matching Annotations
  1. May 2023
  2. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Infusion of hESC derived Immunity-and-matrix regulatory cells improves cognitive ability in early-stage AD mice
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    onlinelibrary.wiley.com/doi/full/10.1111/cpr.13085
  3. Apr 2023
  4. alz-journals.onlinelibrary.wiley.com alz-journals.onlinelibrary.wiley.com
    Pharmacokinetic, pharmacodynamic, and transcriptomic analysis of chronic levetiracetam treatment in 5XFAD mice: A MODEL-AD preclinical testing core study
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    alz-journals.onlinelibrary.wiley.com/doi/full/10.1002/trc2.12329
  5. alz-journals.onlinelibrary.wiley.com alz-journals.onlinelibrary.wiley.com
    INPP5D deficiency attenuates amyloid pathology in a mouse model of Alzheimer's disease
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    alz-journals.onlinelibrary.wiley.com/doi/full/10.1002/alz.12849
  6. onlinelibrary.wiley.com onlinelibrary.wiley.com
    MAC2 is a long-lasting marker of peripheral cell infiltrates into the mouse CNS after bone marrow transplantation and coronavirus infection
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    onlinelibrary.wiley.com/doi/full/10.1002/glia.24144
  7. alz-journals.onlinelibrary.wiley.com alz-journals.onlinelibrary.wiley.com
    The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model
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    alz-journals.onlinelibrary.wiley.com/doi/full/10.1002/alz.12577
  8. Mar 2023
  9. journals.asm.org journals.asm.org
    Longitudinal Analysis of the Microbiome and Metabolome in the 5xfAD Mouse Model of Alzheimer’s Disease
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    journals.asm.org/doi/10.1128/mbio.01794-22
  10. www.biorxiv.org www.biorxiv.org
    Genetic Variants of Phospholipase C-γ2 Confer Altered Microglial Phenotypes and Differential Risk for Alzheimer’s Disease
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    biorxiv.org/content/10.1101/2022.12.08.519685v1
  11. www.biorxiv.org www.biorxiv.org
    Kif11 overexpression rescues cognition, long-term potentiation, and spine defects in mouse and cell models of Alzheimer’s disease
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    biorxiv.org/content/10.1101/2021.09.09.459627v1
  12. www.biorxiv.org www.biorxiv.org
    Hypothalamic gene network dysfunction is associated with cognitive decline and body weight loss in Alzheimer’s disease mice
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    biorxiv.org/content/10.1101/2022.04.08.487664v1
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Alterations in a cross-hemispheric circuit associates with novelty discrimination deficits in mouse models of neurodegeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC9547933/
  14. rupress.org rupress.org
    Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading
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    rupress.org/jem/article/220/1/e20220654/213537/Chronic-TREM2-activation-exacerbates-A-associated
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Periodontal Pathogen Fusobacterium nucleatum Exacerbates Alzheimer’s Pathogenesis via Specific Pathways
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    ncbi.nlm.nih.gov/pmc/articles/PMC9260256/
  16. www.sciencedirect.com www.sciencedirect.com
    INPP5D expression is associated with risk for Alzheimer's disease and induced by plaque-associated microglia
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    sciencedirect.com/science/article/pii/S0969996121000528
  17. www.frontiersin.org www.frontiersin.org
    Idebenone Regulates Aβ and LPS-Induced Neurogliosis and Cognitive Function Through Inhibition of NLRP3 Inflammasome/IL-1β Axis Activation
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    frontiersin.org/articles/10.3389/fimmu.2022.749336/full
  18. www.biorxiv.org www.biorxiv.org
    Longitudinal analysis of the gut microbiome in the 5xfAD mouse model of Alzheimer’s disease
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    biorxiv.org/content/10.1101/2022.03.02.482725v1
  19. Jan 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Spatial proteomics in three-dimensional intact specimens
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    sciencedirect.com/science/article/pii/S0092867422014659
  21. 52.53.155.43 52.53.155.43
    SSRN-id4168479-html.html
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    52.53.155.43/d01d75886eb8224e85413144472a36c3a6fa9512/SSRN-id4168479-html.html
  22. Dec 2022
  23. www.tandfonline.com www.tandfonline.com
    Discovery and engineering of an anti-TREM2 antibody to promote amyloid plaque clearance by microglia in 5XFAD mice
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    tandfonline.com/doi/full/10.1080/19420862.2022.2107971
  24. Nov 2022
  25. link.springer.com link.springer.com
    Protein Expression of Amino Acid Transporters Is Altered in Isolated Cerebral Microvessels of 5xFAD Mouse Model of Alzheimer’s Disease
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    link.springer.com/article/10.1007/s12035-022-03111-y
  26. Aug 2022
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Retinal Vascular Physiology Biomarkers in a 5XFAD Mouse Model of Alzheimer’s Disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC9368483/
  28. alz-journals.onlinelibrary.wiley.com alz-journals.onlinelibrary.wiley.com
    Prophylactic evaluation of verubecestat on disease- and symptom-modifying effects in 5XFAD mice
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    alz-journals.onlinelibrary.wiley.com/doi/full/10.1002/trc2.12317
  29. Apr 2022
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Idebenone Decreases Aβ Pathology by Modulating RAGE/Caspase-3 Signaling and the Aβ Degradation Enzyme NEP in a Mouse Model of AD
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    ncbi.nlm.nih.gov/pmc/articles/PMC8471964/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Brain and Retinal Abnormalities in the 5xFAD Mouse Model of Alzheimer's Disease at Early Stages
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    ncbi.nlm.nih.gov/pmc/articles/PMC8343228/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased tauopathy drives microglia-mediated clearance of beta-amyloid
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    ncbi.nlm.nih.gov/pmc/articles/PMC4918195/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Practical considerations for choosing a mouse model of Alzheimer’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC5741956/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sex differences in the molecular signature of the developing mouse hippocampus
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    ncbi.nlm.nih.gov/pmc/articles/PMC5356301/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rational affinity maturation of anti-amyloid antibodies with high conformational and sequence specificity
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    ncbi.nlm.nih.gov/pmc/articles/PMC8081927/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting MicroRNA-485-3p Blocks Alzheimer’s Disease Progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC8658496/
  37. Nov 2021
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prostaglandin EP2 receptor antagonist ameliorates neuroinflammation in a two-hit mouse model of Alzheimer’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC8605573/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC8519958/
  40. Oct 2021
  41. www.sciencedirect.com www.sciencedirect.com
    Assessment of neurodegeneration and neuronal loss in aged 5XFAD mice
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    sciencedirect.com/science/article/pii/S2666166721006213
  42. Aug 2021
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology
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    ncbi.nlm.nih.gov/pmc/articles/PMC8369003/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Evaluation of the 5XFAD Mouse Model for Preclinical Testing Applications: A MODEL-AD Study
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    ncbi.nlm.nih.gov/pmc/articles/PMC8346252/
  45. Jul 2021
  46. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Genetic background modifies CNS‐mediated sensorimotor decline in the AD‐BXD mouse model of genetic diversity in Alzheimer's disease
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    onlinelibrary.wiley.com/doi/full/10.1111/gbb.12603
  47. www.nature.com www.nature.com
    Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer’s disease
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    nature.com/articles/s41467-019-12242-1
  48. content.iospress.com content.iospress.com
    5xFAD Mice Display Sex-Dependent Inflammatory Gene Induction During the Prodromal Stage of Alzheimer’s Disease
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    content.iospress.com/articles/journal-of-alzheimers-disease/jad180678
  49. www.nature.com www.nature.com
    3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice
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    nature.com/articles/s42003-019-0599-8
  50. www.osapublishing.org www.osapublishing.org
    Supervised learning to quantify amyloidosis in whole brains of an Alzheimer’s disease mouse model acquired with optical projection tomography
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    osapublishing.org/boe/fulltext.cfm
  51. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ultrasensitive Multiparameter Phenotyping of Rare Cells Using an Integrated Digital-Molecular-Counting Microfluidic Well Plate
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    onlinelibrary.wiley.com/doi/full/10.1002/smll.202101743
  52. www.sciencedirect.com www.sciencedirect.com
    Tetrandrine Ameliorated Alzheimer's Disease through Suppressing Microglial Inflammatory Activation and Neurotoxicity in the 5XFAD Mouse
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    sciencedirect.com/science/article/pii/S0944711321001707
  53. Jun 2021
  54. rupress.org rupress.org
    Activated microglia mitigate Aβ-associated tau seeding and spreading
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    rupress.org/jem/article/218/8/e20210542/212263/Activated-microglia-mitigate-A-associated-tau
  55. May 2021
  56. link.springer.com link.springer.com
    MMP9 modulation improves specific neurobehavioral deficits in a mouse model of Alzheimer’s disease
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    link.springer.com/article/10.1186/s12868-021-00643-2
  57. Mar 2021
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rod pathway and cone pathway retinal dysfunction in the 5xFAD mouse model of Alzheimer’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC7921657/
  59. Jan 2021
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Limiting RyR2 Open Time Prevents Alzheimer’s Disease-Related Neuronal Hyperactivity and Memory Loss but Not β-Amyloid Accumulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC7532726/
  61. Nov 2020
  62. onlinelibrary.wiley.com onlinelibrary.wiley.com
    CD11a expression distinguishes infiltrating myeloid cells from plaque‐associated microglia in Alzheimer's disease
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    onlinelibrary.wiley.com/doi/full/10.1002/glia.23575
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microglia facilitate loss of perineuronal nets in the Alzheimer's disease brain
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    ncbi.nlm.nih.gov/pmc/articles/PMC7399129/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aging and Progression of Beta-Amyloid Pathology in Alzheimer’s Disease Correlates with Microglial Heme-Oxygenase-1 Overexpression
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    ncbi.nlm.nih.gov/pmc/articles/PMC7402118/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Retinal Functional and Structural Changes in the 5xFAD Mouse Model of Alzheimer’s Disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC7438734/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antenatal Hypoxia Accelerates the Onset of Alzheimer’s Disease Pathology in 5xFAD Mouse Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC7472639/
  67. Sep 2020
  68. link.springer.com link.springer.com
    Intracranial alternating current stimulation facilitates neurogenesis in a mouse model of Alzheimer’s disease
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    link.springer.com/article/10.1186/s13195-020-00656-9
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptome Analysis of Pineal Glands in the Mouse Model of Alzheimer’s Disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC6962250/
  70. www.sciencedirect.com www.sciencedirect.com
    Behavioural and psychological symptoms of dementia in mouse models of Alzheimer’s disease-related pathology: Running title: BPSD in Alzheimer’s disease models
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    sciencedirect.com/science/article/pii/S0149763419304695
  71. www.sciencedirect.com www.sciencedirect.com
    An optimized method for enrichment of whole brain-derived extracellular vesicles reveals insight into neurodegenerative processes in a mouse model of Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S0165027018301602
  72. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Reduced social investigation and increased injurious behavior in transgenic 5xFAD mice
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    onlinelibrary.wiley.com/doi/full/10.1002/jnr.24578
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Harnessing genetic complexity to enhance translatability of Alzheimer’s disease mouse models: a path towards experimental precision medicine
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    ncbi.nlm.nih.gov/pmc/articles/PMC6886697/
  74. rupress.org rupress.org
    Plaque-associated myeloid cells derive from resident microglia in an Alzheimer’s disease model
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    rupress.org/jem/article/217/4/e20191374/133630/Plaque-associated-myeloid-cells-derive-from
  75. www.nature.com www.nature.com
    3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice
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    nature.com/articles/s42003-019-0599-8.pdf
  76. May 2019
  77. www.karger.com www.karger.com
    Deletion of the Inflammasome Sensor Aim2 Mitigates Aβ Deposition and Microglial Activation but Increases Inflammatory Cytokine Expression in an Alzheimer Disease Mouse Model
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    karger.com/Article/FullText/477092
  78. molecularneurodegeneration.biomedcentral.com molecularneurodegeneration.biomedcentral.com
    BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice
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    molecularneurodegeneration.biomedcentral.com/articles/10.1186/s13024-018-0239-7
  79. www.osapublishing.org www.osapublishing.org
    Optical projection tomography for rapid whole mouse brain imaging
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    osapublishing.org/boe/fulltext.cfm
  80. www.sciencedirect.com www.sciencedirect.com
    Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner
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    sciencedirect.com/science/article/pii/S107476131830075X