345 Matching Annotations
  1. Oct 2021
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    PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation
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    sciencedirect.com/science/article/pii/S2211124721012304
  3. Sep 2021
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    H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity
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    sciencedirect.com/science/article/pii/S1534580721006821
  5. elifesciences.org elifesciences.org
    Niche partitioning facilitates coexistence of closely related honey bee gut bacteria
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    elifesciences.org/articles/68583
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    A nascent polypeptide sequence modulates DnaA translation elongation in response to nutrient availability
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    ncbi.nlm.nih.gov/pmc/articles/PMC8443254/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8387021/
  8. Aug 2021
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    Epigenomic and transcriptional profiling identifies impaired glyoxylate detoxification in NAFLD as a risk factor for hyperoxaluria
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    sciencedirect.com/science/article/pii/S2211124721009578
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    An essential role for the piRNA pathway in regulating the ribosomal RNA pool in C. elegans
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    sciencedirect.com/science/article/pii/S1534580721005979
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    Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation
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    sciencedirect.com/science/article/pii/S1097276521005931
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    CLOCKWORK ORANGE promotes CLOCK-CYCLE activation via the putative Drosophila ortholog of CLOCK INTERACTING PROTEIN CIRCADIAN
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    sciencedirect.com/science/article/pii/S0960982221009726
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    ncbi.nlm.nih.gov/pmc/articles/PMC6344342/
  14. epigeneticsandchromatin.biomedcentral.com epigeneticsandchromatin.biomedcentral.com
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    epigeneticsandchromatin.biomedcentral.com/articles/10.1186/s13072-019-0254-0
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    Gigwa v2—Extended and improved genotype investigator
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    ncbi.nlm.nih.gov/pmc/articles/PMC6511067/
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    sciencedirect.com/science/article/pii/S1074761318304771
  20. Jul 2021
  21. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Glial pathology in a novel spontaneous mutant mouse of the Eif2b5 gene: a vanishing white matter disease model
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14887
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    FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy
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    elifesciences.org/articles/47327
  23. academic.oup.com academic.oup.com
    HUMAN TROPHOBLAST DIFFERENTIATION IS ASSOCIATED WITH PROFOUND GENE REGULATORY AND EPIGENETIC CHANGES
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    academic.oup.com/endo/article-abstract/160/9/2189/5530214
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    HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways
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    elifesciences.org/articles/64148
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    Exon Junction Complexes Suppress Spurious Splice Sites to Safeguard Transcriptome Integrity
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    Native Chromatin Proteomics Reveals a Role for Specific Nucleoporins in Heterochromatin Organization and Maintenance
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    Tyr1 phosphorylation promotes phosphorylation of Ser2 on the C-terminal domain of eukaryotic RNA polymerase II by P-TEFb
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    elifesciences.org/articles/48725
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    A genome‐wide screen identifies IRF2 as a key regulator of caspase‐4 in human cells
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    embopress.org/doi/full/10.15252/embr.201948235
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    Chromosome-scale assemblies reveal the structural evolution of African cichlid genomes
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    academic.oup.com/gigascience/article/8/4/giz030/5426571
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    Global epigenetic analysis of BDNF Val66Met mice hippocampus reveals changes in dendrite and spine remodeling genes
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    onlinelibrary.wiley.com/doi/full/10.1002/hipo.22991
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    BET Inhibition Induces HEXIM1- and RAD51-Dependent Conflicts between Transcription and Replication
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    JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells
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    N6-methyladenine DNA Modification in Glioblastoma
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    SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcing Distinct Chromatin States
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    ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia
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    BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency
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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NANOS2 is a sequence-specific mRNA-binding protein that promotes transcript degradation in spermatogonial stem cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8271163/
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    Deletion of RBMX RGG/RG motif in Shashi-XLID syndrome leads to aberrant p53 activation and neuronal differentiation defects
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  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Next-Generation Sequencing of Cell-Free DNA Extracted From Pleural Effusion Supernatant: Applications and Challenges
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    ncbi.nlm.nih.gov/pmc/articles/PMC8236629/
  40. May 2021
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZC3H4 restricts non-coding transcription in human cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8137146/
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    Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function
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    Derivation of Intermediate Pluripotent Stem Cells Amenable to Primordial Germ Cell Specification
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    A Prion-like Domain in Transcription Factor EBF1 Promotes Phase Separation and Enables B Cell Programming of Progenitor Chromatin
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    A single-cell analysis of the Arabidopsis vegetative shoot apex
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    Chromatin Accessibility Dynamics and a Hierarchical Transcriptional Regulatory Network Structure for Plant Somatic Embryogenesis
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  47. Apr 2021
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    Analysis of Brugada syndrome loci reveals that fine-mapping clustered GWAS hits enhances the annotation of disease-relevant variants
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    sciencedirect.com/science/article/pii/S2666379121000665
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    Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form
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    The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr
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    sciencedirect.com/science/article/pii/S1931312821001013
  51. Mar 2021
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inducible mechanisms of disease tolerance provide an alternative strategy of acquired immunity to malaria
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    ncbi.nlm.nih.gov/pmc/articles/PMC7987336/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ectopic humanized mesenchymal niche in mice enables robust engraftment of myelodysplastic stem cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC7610449/
  54. academic.oup.com academic.oup.com
    Germline EGFR variants are over-represented in adolescents and young adults (AYA) with adrenocortical carcinoma
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    academic.oup.com/hmg/article/29/22/3679/6035190
  55. Feb 2021
  56. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
    Combined Gene Expression and Chromatin Immunoprecipitation From a Single Mouse Hippocampus
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    currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cpz1.33
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The origins and consequences of UPF1 variants in pancreatic adenosquamous carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC7846273/
  58. Jan 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Protocol for assaying chromatin accessibility using ATAC-seq in plants
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    sciencedirect.com/science/article/pii/S2666166720302768
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    QUAKING Regulates Microexon Alternative Splicing of the Rho GTPase Pathway and Controls Microglia Homeostasis
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    sciencedirect.com/science/article/pii/S2211124720315497
  61. Dec 2020
  62. www.nature.com www.nature.com
    SVA retrotransposon insertion in exon of MMR genes results in aberrant RNA splicing and causes Lynch syndrome
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    nature.com/articles/s41431-020-00779-5
  63. Oct 2020
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    Widespread Transcriptional Readthrough Caused by Nab2 Depletion Leads to Chimeric Transcripts with Retained Introns
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    sciencedirect.com/science/article/pii/S2211124720313139
  65. academic.oup.com academic.oup.com
    DNA Methylation Profiling and Genomic Analysis in 20 Children with Short Stature Who Were Born Small for Gestational Age
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    academic.oup.com/jcem/article/105/12/dgaa465/5873625
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in human lung adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC7556868/
  67. Sep 2020
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    Structure-Mediated RNA Decay by UPF1 and G3BP1
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  69. elifesciences.org elifesciences.org
    Transposase-assisted tagmentation of RNA/DNA hybrid duplexes
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    elifesciences.org/articles/54919
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    Aneuploidy as a cause of impaired chromatin silencing and mating-type specification in budding yeast
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    elifesciences.org/articles/27991
  71. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Long-read only assembly of Drechmeria coniospora genomes reveals widespread chromosome plasticity and illustrates the limitations of current nanopore methods
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    pubmed.ncbi.nlm.nih.gov/32947622/
  72. link.springer.com link.springer.com
    Identification of novel fusion transcripts in meningioma
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    link.springer.com/article/10.1007/s11060-020-03599-1
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    OsNSUN2-Mediated 5-Methylcytosine mRNA Modification Enhances Rice Adaptation to High Temperature
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    The histone modification reader ZCWPW1 links histone methylation to PRDM9-induced double-strand break repair
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    elifesciences.org/articles/53459
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Building the vertebrate codex using the gene breaking protein trap library
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    ncbi.nlm.nih.gov/pmc/articles/PMC7486118/
  76. elifesciences.org elifesciences.org
    Deletion of Stk11 and Fos in mouse BLA projection neurons alters intrinsic excitability and impairs formation of long-term aversive memory
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    elifesciences.org/articles/61036
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGFβ signaling in triple-negative breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC7302877/
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    LINE-1 specific nuclear organization in mice olfactory sensory neurons
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    Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance
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    Resolving the 3D Landscape of Transcription-Linked Mammalian Chromatin Folding
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    Nascent Transcript Folding Plays a Major Role in Determining RNA Polymerase Elongation Rates
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    Expandable and reversible copy number amplification drives rapid adaptation to antifungal drugs
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    ncbi.nlm.nih.gov/pmc/articles/PMC7371428/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta
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    ncbi.nlm.nih.gov/pmc/articles/PMC7054001/
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    Regulatory Dynamics of Tet1 and Oct4 Resolve Stages of Global DNA Demethylation and Transcriptomic Changes in Reprogramming
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  85. Jan 2020
  86. elifesciences.org elifesciences.org
    Evolution of Yin and Yang isoforms of a chromatin remodeling subunit precedes the creation of two genes
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    elifesciences.org/articles/48119
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    Large, three-generation human families reveal post-zygotic mosaicism and variability in germline mutation accumulation
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    elifesciences.org/articles/46922
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    RNA Interactions Are Essential for CTCF-Mediated Genome Organization
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    GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome plasticity in Candida albicans is driven by long repeat sequences
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    P Granules Protect RNA Interference Genes from Silencing by piRNAs
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    Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling
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    A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity
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    Genome-wide Analyses of Chromatin State in Human Mast Cells Reveal Molecular Drivers and Mediators of Allergic and Inflammatory Diseases
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    ERG Controls B Cell Development by Promoting Igh V-to-DJ Recombination
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    Endodermal Maternal Transcription Factors Establish Super-Enhancers during Zygotic Genome Activation
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    Meta-analysis of Chromatin Programming by Steroid Receptors
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    DUX4 Suppresses MHC Class I to Promote Cancer Immune Evasion and Resistance to Checkpoint Blockade
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    Continuous and Discrete Neuron Types of the Adult Murine Striatum
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    Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF
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    Maternal Ribosomes Are Sufficient for Tissue Diversification during Embryonic Development in C. elegans
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    Dynamic transcriptome profiling dataset of vaccinia virus obtained from long-read sequencing techniques
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