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Nov 2020
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Identification of ubiquitin Ser57 kinases regulating the oxidative stress response in yeast

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1. scibot 12 Nov 2020
  
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  DOI: 10.7554/eLife.58155
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7647399/
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An epilepsy‐associated ACTL6B variant captures neuronal hyperexcitability in a human induced pluripotent stem cell model

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1. scibot 05 Nov 2020
  
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  DOI: 10.1002/jnr.24747
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.24747
Sep 2020
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Reduced expression of the PP2A methylesterase, PME-1, or the PP2A methyltransferase, LCMT-1, alter sensitivity to beta-amyloid induced cognitive and electrophysiological impairments in mice

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1. scibot 16 Sep 2020
  
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jneurosci.org/content/40/23/4596
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Stxbp1/Munc18-1 haploinsufficiency impairs inhibition and mediates key neurological features of STXBP1 encephalopathy

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1. scibot 15 Sep 2020
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7056272/
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ParB spreading on DNA requires cytidine triphosphate in vitro

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1. scibot 15 Sep 2020
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7053999/
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Nef-Mediated CD3-TCR Downmodulation Dampens Acute Inflammation and Promotes SIV Immune Evasion

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1. scibot 13 Sep 2020
  
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Altered Sexual Behavior in Dopamine Transporter (DAT) Knockout Male Rats: A Behavioral, Neurochemical and Intracerebral Microdialysis Study

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1. scibot 13 Sep 2020
  
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  DOI: 10.3389/fnbeh.2020.00058
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7185326/
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Partial loss of CFIm25 causes learning deficits and aberrant neuronal alternative polyadenylation

1
1. scibot 12 Sep 2020
  
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  DOI: 10.7554/eLife.50895
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7176433/
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Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagy

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1. scibot 11 Sep 2020
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6984822/
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LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses

1
1. scibot 08 Sep 2020
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6984820/
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Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions

1
1. scibot 05 Sep 2020
  
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  DOI: 10.7554/eLife.49894
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6959991/
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Endolysosomal Targeting of Mitochondria Is Integral to BAX-Mediated Mitochondrial Permeabilization during Apoptosis Signaling

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1. scibot 05 Sep 2020
  
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  DOI: 10.1016/j.devcel.2020.05.014
  
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sciencedirect.com/science/article/pii/S1534580720304032
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Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum

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1. scibot 03 Sep 2020
  
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  DOI: 10.7554/eLife.54443
  
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Aug 2020
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Complexin Suppresses Spontaneous Exocytosis by Capturing the Membrane-Proximal Regions of VAMP2 and SNAP25

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1. scibot 25 Aug 2020
  
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  DOI: 10.1016/j.celrep.2020.107926
  
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sciencedirect.com/science/article/pii/S2211124720309074
Jan 2020
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Transcriptional Regulation of the Glutamate/GABA/Glutamine Cycle in Adult Glia Controls Motor Activity and Seizures in Drosophila

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1. scibot 13 Jan 2020
  
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  DOI: 10.1523/JNEUROSCI.1833-18.2019
  
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jneurosci.org/content/39/27/5269
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Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.cell.2019.10.044
  
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sciencedirect.com/science/article/pii/S0092867419312218
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DHA and its derived lipid mediators MaR1, RvD1 and RvD2, block TNF-α inhibition of intestinal sugar and glutamine uptake in Caco-2 cells

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.jnutbio.2019.108264
  
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2. scibot 13 Jan 2020
  
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  RRID:SCR_014211
  
  DOI: 10.1016/j.jnutbio.2019.108264
  
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sciencedirect.com/science/article/pii/S0955286319301925
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PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.molcel.2019.10.008
  
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sciencedirect.com/science/article/pii/S1097276519307683
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Lovastatin, not Simvastatin, Corrects Core Phenotypes in the Fragile X Mouse Model

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1. scibot 13 Jan 2020
  
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  RRID:SCR_013715
  
  DOI: 10.1523/ENEURO.0097-19.2019
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6565377/
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Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses

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  DOI: 10.1016/j.cell.2019.09.011
  
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sciencedirect.com/science/article/pii/S0092867419310177
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Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection

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  DOI: 10.1016/j.molcel.2019.11.007
  
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sciencedirect.com/science/article/pii/S1097276519308366
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IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation

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  DOI: 10.1016/j.chom.2019.05.002
  
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sciencedirect.com/science/article/pii/S1931312819302471
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Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells

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  DOI: 10.7554/eLife.46043
  
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elifesciences.org/articles/46043
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Untitled document

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  DOI: 10.1016/j.celrep.2019.02.030
  
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sciencedirect.com/science/article/pii/S2211124719302013
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Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Modulates Lifespan

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  DOI: 10.1016/j.cub.2019.01.029
  
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sciencedirect.com/science/article/pii/S0960982219300314
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Untitled document

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  DOI: 10.1016/j.celrep.2019.04.063
  
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sciencedirect.com/science/article/pii/S2211124719305364
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Untitled document

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  DOI: 10.7554/eLife.41930
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6372280/
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Pyk2 Signaling through Graf1 and RhoA GTPase Is Required for Amyloid-β Oligomer-Triggered Synapse Loss

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  DOI: 10.1523/JNEUROSCI.2983-18.2018
  
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jneurosci.org/content/39/10/1910
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A Chaperone Lid Ensures Efficient and Privileged Client Transfer during Tail-Anchored Protein Targeting

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  DOI: 10.1016/j.celrep.2018.12.035
  
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sciencedirect.com/science/article/pii/S221112471831965X
Nov 2018
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The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1074761318304357
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A Short Tandem Repeat-Enriched RNA Assembles a Nuclear Compartment to Control Alternative Splicing and Promote Cell Survival

1
1. scibot 05 Nov 2018
  
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Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage

1
1. scibot 05 Nov 2018
  
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  Odyssey imaging system
  
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ncbi.nlm.nih.govhttp://europepmc.org/articles/PMC6127031/
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Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A

1
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sciencedirect.com/science/article/pii/S155041311830514X
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Mitochondrial DNA Variation Dictates Expressivity and Progression of Nuclear DNA Mutations Causing Cardiomyopathy

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1. scibot 05 Nov 2018
  
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  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S1550413118305035
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Neuregulin 1 Type I Overexpression Is Associated with Reduced NMDA Receptor–Mediated Synaptic Signaling in Hippocampal Interneurons Expressing PV or CCK

1
1. scibot 05 Nov 2018
  
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  SCR:014211
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5938717/
elifesciences.org elifesciences.org

Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy

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elifesciences.org/articles/29626
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Untitled document

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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5701795/
Nov 2017
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Distinct Roles of the Chromosomal Passenger Complex in the Detection of and Response to Errors in Kinetochore-Microtubule Attachment

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1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S1534580717306822
onlinelibrary.wiley.com onlinelibrary.wiley.com

Protein kinase D exerts neuroprotective functions during oxidative stress via Nuclear Factor kappaB‐independent signaling pathways

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onlinelibrary.wiley.com/doi/10.1111/jnc.14131/full
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Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice

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1. scibot 08 Nov 2017
  
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jneurosci.org/content/37/25/6132
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Reciprocal regulation of ARPP-16 by PKA and MAST3 kinases provides a cAMP-regulated switch in protein phosphatase 2A inhibition

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1. scibot 08 Nov 2017
  
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elifesciences.org/articles/24998
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ARPP-16 Is a Striatal-Enriched Inhibitor of Protein Phosphatase 2A Regulated by Microtubule-Associated Serine/Threonine Kinase 3 (Mast 3 Kinase)

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jneurosci.org/content/37/10/2709
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A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability

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1. scibot 08 Nov 2017
  
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  SCR_013715
  
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sciencedirect.com/science/article/pii/S0092867417305378
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Prolactin-induced neuroprotection against glutamate excitotoxicity is mediated by the reduction of [Ca2+]i overload and NF-κB activation

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1. scibot 08 Nov 2017
  
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A model for regulation by SynGAP-α1 of binding of synaptic proteins to PDZ-domain 'Slots' in the postsynaptic density

1
1. scibot 08 Nov 2017
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5040590/
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Combinatorial synthesis and screening of cancer cell-specific nanomedicines targeted via phage fusion proteins

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1. scibot 08 Nov 2017
  
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ncbi.nlm.nih.gov/pmc/articles/PMC4477153/
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Dysregulation of Kv3.4 Channels in Dorsal Root Ganglia Following Spinal Cord Injury

1
1. scibot 08 Nov 2017
  
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ncbi.nlm.nih.gov/pmc/articles/PMC4300326/
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Phosphorylation of Synaptic GTPase-activating Protein (synGAP) by Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII) and Cyclin-dependent Kinase 5 (CDK5) Alters the Ratio of Its GAP Activity toward Ras and Rap GTPases

1
1. scibot 08 Nov 2017
  
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jbc.org/content/290/8/4908.long
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Activity-Dependent Regulation of Dendritic Complexity by Semaphorin 3A through Farp1

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1. scibot 08 Nov 2017
  
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  Odyssey Imaging System
  
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ncbi.nlm.nih.gov/pmc/articles/PMC4044256/
elifesciences.org elifesciences.org

Registered report: Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

1
1. scibot 08 Nov 2017
  
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elifesciences.org/content/3/e04034
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Registered report: Widespread potential for growth factor-driven resistance to anticancer kinase inhibitors

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1. scibot 08 Nov 2017
  
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  Curator: @gabimpine
  
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elifesciences.org/content/3/e04037