217 Matching Annotations
  1. Nov 2024
  2. www.biorxiv.org www.biorxiv.org
    Loss of mitochondrial enzyme GPT2 leads to reprogramming of synaptic glutamate metabolism
    1
    1. scibot 14 Nov 2024
      RRID:SCR_013715

      DOI: 10.1101/2024.11.06.622291

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    biorxiv.org/content/10.1101/2024.11.06.622291v1
  3. link.springer.com link.springer.com
    Multi-Omics Approach Reveals Genes and Pathways Affected in Miller-Dieker Syndrome
    1
    1. scibot 14 Nov 2024
      RRID:SCR_013715

      DOI: 10.1007/s12035-024-04532-7

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    link.springer.com/article/10.1007/s12035-024-04532-7
  4. Sep 2024
  5. www.sciencedirect.com www.sciencedirect.com
    Antibacterial action, proteolytic immunity, and in vivo activity of a Vibrio cholerae microcin
    1
    1. scibot 11 Sep 2024
      SCR_013715

      DOI: 10.1016/j.chom.2024.08.012

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    sciencedirect.com/science/article/pii/S1931312824003196
  6. www.sciencedirect.com www.sciencedirect.com
    Diabesity alters the protective effects of estrogens on endothelial function through adipose tissue secretome
    1
    1. scibot 10 Sep 2024
      RRID:SCR_013715

      DOI: 10.1016/j.freeradbiomed.2024.09.001

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    sciencedirect.com/science/article/pii/S0891584924006397
  7. Aug 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells
    1
    1. scibot 23 Aug 2024
      RRID:SCR_013715

      DOI: 10.7554/eLife.76940

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    ncbi.nlm.nih.gov/pmc/articles/PMC11333044/
  9. www.biorxiv.org www.biorxiv.org
    Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s linked-LRRK2 mutant mice
    1
    1. scibot 20 Aug 2024
      RRID:SCR_013715

      DOI: 10.1101/2024.07.31.606089

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    biorxiv.org/content/10.1101/2024.07.31.606089v1
  10. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Distribution of the SynDIG4/proline‐rich transmembrane protein 1 in rat brain
    1
    1. scibot 02 Aug 2024
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      DOI: 10.1002/cne.23945

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    onlinelibrary.wiley.com/doi/10.1002/cne.23945/full
  11. www.sciencedirect.com www.sciencedirect.com
    The V-ATPase/ATG16L1 axis is controlled by the V1H subunit
    1
    1. scibot 01 Aug 2024
      RRID:SCR_013715

      DOI: 10.1016/j.molcel.2024.07.003

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    sciencedirect.com/science/article/pii/S1097276524005793
  12. Jul 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A recurrent missense variant in the E3 ubiquitin ligase substrate recognition subunit FEM1B causes a rare syndromic neurodevelopmental disorder
    1
    1. scibot 20 Jul 2024
      RRID:SCR_013715

      DOI: 10.1016/j.gim.2024.101119

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    ncbi.nlm.nih.gov/pmc/articles/PMC11257750/
  14. www.sciencedirect.com www.sciencedirect.com
    Evolution of ion transporter Na+/K+-ATPase expression in the osmoregulatory maxillary glands of an invasive copepod
    1
    1. scibot 18 Jul 2024
      RRID:SCR_013715

      DOI: 10.1016/j.isci.2024.110278

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    sciencedirect.com/science/article/pii/S2589004224015037
  15. Jun 2024
  16. 52.53.155.43 52.53.155.43
    elife-92755-v2-html.html
    1
    1. scibot 07 Jun 2024
      SCR_013715

      DOI: 10.7554/elife.92755

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    52.53.155.43/82e9bd136d23c9ba72ae36fc3bdfe32c939ebcb6/elife-92755-v2-html.html
  17. May 2024
  18. www.sciencedirect.com www.sciencedirect.com
    The C-terminal disordered loop domain of Apc8 unlocks APC/C mitotic activation
    1
    1. scibot 23 May 2024
      RRID:SCR_013715

      DOI: 10.1016/j.celrep.2024.114262

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    sciencedirect.com/science/article/pii/S2211124724005904
  19. www.sciencedirect.com www.sciencedirect.com
    Mixing energy drinks and alcohol during adolescence impairs brain function: a study of rat hippocampal plasticity
    1
    1. scibot 14 May 2024
      RRID:SCR_014211

      DOI: 10.1016/j.neuropharm.2024.109993

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    sciencedirect.com/science/article/pii/S002839082400162X
  20. www.sciencedirect.com www.sciencedirect.com
    The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex
    1
    1. scibot 07 May 2024
      RRID:SCR_013715

      DOI: 10.1016/j.molcel.2024.04.007

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    sciencedirect.com/science/article/pii/S1097276524002855
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of tumor-associated AXIN1 missense mutations identifies variants that activate β-catenin signaling
    1
    1. scibot 04 May 2024
      RRID:SCR_013715

      DOI: 10.1158/0008-5472.CAN-23-2268

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    ncbi.nlm.nih.gov/pmc/articles/PMC11063763/
  22. Apr 2024
  23. 52.53.155.43 52.53.155.43
    elife-92755-v2-html.html
    1
    1. scibot 13 Apr 2024
      SCR_013715

      DOI: 10.7554/elife.92755

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    52.53.155.43/82e9bd136d23c9ba72ae36fc3bdfe32c939ebcb6/elife-92755-v2-html.html
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAD51 separation of function mutation disables replication fork maintenance but preserves DSB repair
    1
    1. scibot 10 Apr 2024
      RRID:SCR_013715

      DOI: 10.1016/j.isci.2024.109524

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    ncbi.nlm.nih.gov/pmc/articles/PMC10993188/
  25. Mar 2024
  26. www.sciencedirect.com www.sciencedirect.com
    A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children
    1
    1. scibot 29 Mar 2024
      RRID:SCR_013715

      DOI: 10.1016/j.xgen.2024.100526

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    sciencedirect.com/science/article/pii/S2666979X24000685
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rho GTPase signaling and mDia facilitate endocytosis via presynaptic actin
    1
    1. scibot 22 Mar 2024
      RRID:SCR_013715

      DOI: 10.7554/eLife.92755

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    ncbi.nlm.nih.gov/pmc/articles/PMC10950329/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Control of meiotic entry by dual inhibition of a key mitotic transcription factor
    1
    1. scibot 16 Mar 2024
      RRID:SCR_013715

      DOI: 10.7554/eLife.90425

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    ncbi.nlm.nih.gov/pmc/articles/PMC10939502/
  29. insight.jci.org insight.jci.org
    Epigenetic drug screening defines a PRMT5 inhibitor sensitive pancreatic cancer subtype
    1
    1. scibot 08 Mar 2024
      RRID:SCR_013715

      DOI: 10.1172/jci.insight.151353

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    insight.jci.org/articles/view/151353
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An optimized protocol for the extraction and quantification of cytosolic DNA in mammalian cells
    1
    1. scibot 02 Mar 2024
      RRID:SCR_013715

      DOI: 10.1016/j.xpro.2024.102913

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    ncbi.nlm.nih.gov/pmc/articles/PMC10901131/
  31. Feb 2024
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkinson’s VPS35[D620N] mutation induces LRRK2-mediated lysosomal association of RILPL1 and TMEM55B
    1
    1. scibot 10 Feb 2024
      RRID:SCR_013715

      DOI: 10.1126/sciadv.adj1205

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    ncbi.nlm.nih.gov/pmc/articles/PMC10848721/
  33. 52.53.155.43 52.53.155.43
    Influenza A virus propagation requires the activation of the unfolded protein response and the accumulation of insoluble protein aggregates
    1
    1. scibot 09 Feb 2024
      RRID:SCR_013715

      DOI: 10.1016/j.isci.2024.109100

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    52.53.155.43/d3d22b34dc913e3c2adad8dc51a7839208721c99/PIIS2589004224003213-html.html
  34. www.sciencedirect.com www.sciencedirect.com
    Glia trigger endocytic clearance of axonal proteins to promote rodent myelination
    1
    1. scibot 06 Feb 2024
      RRID:SCR_013715

      DOI: 10.1016/j.devcel.2024.01.008

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    sciencedirect.com/science/article/pii/S1534580724000285
  35. Jan 2024
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD73-dependent generation of extracellular adenosine by vascular endothelial cells modulates de novo lipogenesis in adipose tissue
    1
    1. scibot 26 Jan 2024
      SCR_013715

      DOI: 10.3389/fimmu.2023.1308456

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    ncbi.nlm.nih.gov/pmc/articles/PMC10803534/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systems-level analyses dissociate genetic regulators of reactive oxygen species and energy production
    1
    1. scibot 24 Jan 2024
      RRID:SCR_013715

      DOI: 10.1073/pnas.2307904121

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    ncbi.nlm.nih.gov/pmc/articles/PMC10801874/
  38. www.sciencedirect.com www.sciencedirect.com
    Downregulation of the kidney glucagon receptor, essential for renal function and systemic homeostasis, contributes to chronic kidney disease
    1
    1. scibot 19 Jan 2024
      RRID:SCR_013715

      DOI: 10.1016/j.cmet.2023.12.024

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    sciencedirect.com/science/article/pii/S1550413123004758
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In situ modeling of acquired resistance to RTK/RAS pathway targeted therapies
    1
    1. scibot 18 Jan 2024
      RRID:SCR_013715

      DOI: 10.1016/j.isci.2023.108711

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC10788224/
  40. www.science.org www.science.org
    Parkinson’s VPS35[D620N] mutation induces LRRK2-mediated lysosomal association of RILPL1 and TMEM55B
    1
    1. scibot 12 Jan 2024
      RRID:SCR_013715

      DOI: 10.1126/sciadv.adj1205

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    science.org/doi/10.1126/sciadv.adj1205
  41. Dec 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression
    1
    1. scibot 28 Dec 2023
      RRID:SCR_013715

      DOI: 10.1158/0008-5472.CAN-23-1252

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    ncbi.nlm.nih.gov/pmc/articles/PMC10740391/
  43. www.sciencedirect.com www.sciencedirect.com
    Voice categorization in the four-month-old human brain
    1
    1. scibot 16 Dec 2023
      SCR_013715

      DOI: 10.1016/j.cub.2023.11.042

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    sciencedirect.com/science/article/pii/S0960982223015920
  44. elifesciences.org elifesciences.org
    Rab12 is a regulator of LRRK2 and its activation by damaged lysosomes
    1
    1. scibot 15 Dec 2023
      RRID:SCR_013715

      DOI: 10.7554/eLife.87255

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    elifesciences.org/articles/87255
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase
    1
    1. scibot 15 Dec 2023
      RRID:SCR_013715

      DOI: 10.7554/eLife.87098

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    ncbi.nlm.nih.gov/pmc/articles/PMC10708890/
  46. link.springer.com link.springer.com
    Development and validation of an expanded antibody toolset that captures alpha-synuclein pathological diversity in Lewy body diseases
    1
    1. scibot 08 Dec 2023
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      DOI: 10.1038/s41531-023-00604-y

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    link.springer.com/article/10.1038/s41531-023-00604-y
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinin B1 receptor controls maternal adiponectin levels and influences offspring weight gain
    1
    1. scibot 07 Dec 2023
      RRID:SCR_013715

      DOI: 10.1016/j.isci.2023.108409

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    ncbi.nlm.nih.gov/pmc/articles/PMC10696114/
  48. www.sciencedirect.com www.sciencedirect.com
    Development of a monoclonal antibody specific for a calpain-generated ∆48 kDa calcineurin fragment, a marker of distressed astrocytes
    1
    1. scibot 01 Dec 2023
      RRID:SCR_013715

      DOI: 10.1016/j.jneumeth.2023.110012

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    sciencedirect.com/science/article/pii/S0165027023002315
  49. Oct 2023
  50. www.biorxiv.org www.biorxiv.org
    Systems-level analyses dissociate genetic regulators of reactive oxygen species and energy production
    1
    1. scibot 24 Oct 2023
      RRID:SCR_013715

      DOI: 10.1101/2023.10.14.562276

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    biorxiv.org/content/10.1101/2023.10.14.562276v1
  51. aacrjournals.org aacrjournals.org
    Piperacetazine directly binds to the PAX3::FOXO1 fusion protein and inhibits its transcriptional activity.
    1
    1. scibot 07 Oct 2023
      RRID:SCR_013715

      DOI: 10.1158/2767-9764.CRC-23-0119

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    aacrjournals.org/cancerrescommun/article/3/10/2030/729478/Piperacetazine-Directly-Binds-to-the-PAX3-FOXO1
  52. Sep 2023
  53. www.sciencedirect.com www.sciencedirect.com
    Sphingosine Kinase 1 is Involved in Triglyceride Breakdown by Maintaining Lysosomal Integrity in Brown Adipocytes
    1
    1. scibot 30 Sep 2023
      RRID:SCR_013715

      DOI: 10.1016/j.jlr.2023.100450

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    COR758, a negative allosteric modulator of GABAB receptors
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    Microglia contribute to cognitive decline in hypercholesterolemic LDLr−/− mice
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  56. Aug 2023
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    A Novel Mouse Model of Combined Hepatocellular-Cholangiocarcinoma Induced by Diethylnitrosamine and Loss of Ppp2r5d
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      DOI: 10.3390/cancers15164193

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    Neuronal γ-secretase regulates lipid metabolism, linking cholesterol to synaptic dysfunction in Alzheimer’s disease
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  60. Jul 2023
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF1R inhibition enhances the therapeutic effects of Gq/11 inhibition in metastatic uveal melanoma progression
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      DOI: 10.1158/1535-7163.MCT-22-0147

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  62. www.biorxiv.org www.biorxiv.org
    Parkinson’s VP535[D620N] mutation induces LRRK2 mediated lysosomal association of RILPL1 and TMEM55B
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  63. Jun 2023
  64. www.embopress.org www.embopress.org
    PARK15/FBXO7 is dispensable for PINK1/Parkin mitophagy in iNeurons and HeLa cell systems
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    Effects of Tail Pinch on BDNF and trkB Expression in the Hippocampus of Roman Low- (RLA) and High-Avoidance (RHA) Rats
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  66. May 2023
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BAP1 loss is associated with higher ASS1 expression in epithelioid mesothelioma: implications for therapeutic stratification.
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      DOI: 10.1158/1541-7786.MCR-22-0635

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  68. Apr 2023
  69. www.sciencedirect.com www.sciencedirect.com
    C9ORF72 suppresses JAK-STAT mediated inflammation
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    Development of a 5-HT7 receptor antibody for the rat: the good, the bad, and the ugly
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  71. Mar 2023
  72. www.sciencedirect.com www.sciencedirect.com
    The amino-dipeptidyl peptidases DPP8 and DPP9: Purification and enzymatic assays
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    Leaked genomic and mitochondrial DNA contribute to the host response to noroviruses in a STING-dependent manner
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    Orai3 and Orai1 mediate CRAC channel function and metabolic reprogramming in B cells
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      DOI: 10.7554/eLife.84708

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    Lactate exposure shapes the metabolic and transcriptomic profile of CD8+ T cells
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    Lysosomal trafficking of the glucose transporter GLUT1 requires sequential regulation by TXNIP and ubiquitin
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  77. Feb 2023
  78. www.sciencedirect.com www.sciencedirect.com
    Protein Kinase A Activation Alleviates Cataract Formation via Increased Gap Junction Intercellular Communication
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  79. www.nature.com www.nature.com
    Mutations in Parkinsonism-linked endocytic proteins synaptojanin1 and auxilin have synergistic effects on dopaminergic axonal pathology
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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antisense oligonucleotide therapy rescues disturbed brain rhythms and sleep in juvenile and adult mouse models of Angelman syndrome
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    Peroxiredoxin 2 is required for the redox mediated adaptation to exercise
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  82. Jan 2023
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    Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues
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  84. Dec 2022
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    Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis
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    AP1/Fra1 confers resistance to MAPK cascade inhibition in pancreatic cancer
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      DOI: 10.1007/s00018-022-04638-y

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    NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors
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      DOI: 10.1126/sciadv.abq0648

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  88. www.science.org www.science.org
    NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors
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  89. www.nature.com www.nature.com
    Structural basis for Parkinson’s disease-linked LRRK2’s binding to microtubules
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      DOI: 10.1038/s41594-022-00863-y

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    Acute Stress Induces Different Changes on the Expression of BDNF and trkB in the Mesocorticolimbic System of Two Lines of Rats Differing in Their Response to Stressors
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    A RADAR method to measure DNA topoisomerase covalent complexes
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  92. Nov 2022
  93. www.sciencedirect.com www.sciencedirect.com
    Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation
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      DOI: 10.1016/j.molcel.2022.11.002

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    Laminin-α4 negatively regulates adipocyte beiging through the suppression of AMPKα in male mice
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      DOI: 10.1210/endocr/bqac154

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    Na+/H+-exchanger 1 enhances antitumor activity of engineered NK-92 natural killer cells
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      DOI: 10.1158/2767-9764.crc-22-0270

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    CD8+ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation
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  97. Oct 2022
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemotherapeutic drug screening in 3D-Bioengineered human myobundles provides insight into taxane-induced myotoxicities
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    Hyperactivation of mTORC1 in a double hit mutant zebrafish model of tuberous sclerosis complex causes increased seizure susceptibility and neurodevelopmental abnormalities
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      DOI: 10.3389/fcell.2022.952832

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  100. Sep 2022
  101. www.embopress.org www.embopress.org
    Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair
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    FOXA1 regulates alternative splicing in prostate cancer
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    Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding
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      DOI: 10.1042/BCJ20220161

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  104. aacrjournals.org aacrjournals.org
    Na+/H+-exchanger 1 Enhances Antitumor Activity of Engineered NK-92 Natural Killer Cells
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  105. Aug 2022
  106. www.nature.com www.nature.com
    Carbon nanoparticles adversely affect CFTR expression and toxicologically relevant pathways
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      DOI: 10.1038/s41598-022-18098-8

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    nature.com/articles/s41598-022-18098-8
  107. link.springer.com link.springer.com
    Adolescent self-administration of the synthetic cannabinoid receptor agonist JWH-018 induces neurobiological and behavioral alterations in adult male mice
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      DOI: 10.1007/s00213-022-06191-9

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  108. Jun 2022
  109. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuroplastic changes in c-Fos, ΔFosB, BDNF, trkB, and Arc expression in the hippocampus of male Roman rats: differential effects of sexual activity
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      DOI: 10.1002/hipo.23448

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    onlinelibrary.wiley.com/doi/10.1002/hipo.23448
  110. aacrjournals.org aacrjournals.org
    Porcupine inhibition disrupts mitochondrial function and homeostasis in WNT ligand-addicted pancreatic cancer
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      DOI: 10.1158/1535-7163.MCT-21-0623

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    aacrjournals.org/mct/article/21/6/936/699192/Porcupine-Inhibition-Disrupts-Mitochondrial
  111. May 2022
  112. www.sciencedirect.com www.sciencedirect.com
    The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling
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      DOI: 10.1016/j.celrep.2022.110811

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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity
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      DOI: 10.1126/sciadv.abn0044

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  114. link.springer.com link.springer.com
    Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy
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      DOI: 10.1186/s13024-022-00526-y

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  115. www.science.org www.science.org
    A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity
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      DOI: 10.1126/sciadv.abn0044

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  116. Mar 2022
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The TFIIH complex is required to establish and maintain mitotic chromosome structure
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      DOI: 10.7554/eLife.75475

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    ncbi.nlm.nih.gov/pmc/articles/PMC8956287/
  118. www.sciencedirect.com www.sciencedirect.com
    Loss of mouse Stmn2 function causes motor neuropathy
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      DOI: 10.1016/j.neuron.2022.02.011

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    Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy
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      DOI: 10.1016/j.neuron.2022.01.035

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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Staphylococcus aureus β-Toxin Exerts Anti-angiogenic Effects by Inhibiting Re-endothelialization and Neovessel Formation
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      DOI: 10.3389/fmicb.2022.840236

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  121. Feb 2022
  122. www.embopress.org www.embopress.org
    Identification of treatment-induced vulnerabilities in pancreatic cancer patients using functional model systems
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      DOI: 10.15252/emmm.202114876

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    Unconcerted conformational changes in Arp2/3 complex integrate multiple activating signals to assemble functional actin networks
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  124. Jan 2022
  125. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      DOI: 10.1111/bph.15744

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15744
  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Salivary ZG16B expression loss follows exocrine gland dysfunction related to oral Chronic Graft-Versus-Host Disease
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      DOI: 10.1016/j.isci.2021.103592

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    ncbi.nlm.nih.gov/pmc/articles/PMC8718990/
  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Triple targeting of breast tumors driven by hormonal receptors and HER2
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      DOI: 10.1158/1535-7163.MCT-21-0098

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    ncbi.nlm.nih.gov/pmc/articles/PMC8742793/
  128. Dec 2021
  129. www.sciencedirect.com www.sciencedirect.com
    Disrupted expression of mitochondrial NCLX sensitizes neuroglial networks to excitotoxic stimuli and renders synaptic activity toxic
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      DOI: 10.1016/j.jbc.2021.101508

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    sciencedirect.com/science/article/pii/S0021925821013181
  130. www.sciencedirect.com www.sciencedirect.com
    Identification of RAS mutant biomarkers for EGFR inhibitor sensitivity using a systems biochemical approach
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      DOI: 10.1016/j.celrep.2021.110096

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    sciencedirect.com/science/article/pii/S2211124721015904
  131. Nov 2021
  132. academic.oup.com academic.oup.com
    Mitochondrial enzyme GPT2 regulates metabolic mechanisms required for neuron growth and motor function in vivo
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      DOI: 10.1093/hmg/ddab269

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    academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddab269/6369826
  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A single aromatic residue in sgp130Fc (olamkicept) allows the discrimination between interleukin-6 (IL-6) and IL-11 trans-signaling
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      DOI: 10.1016/j.isci.2021.103309

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  134. www.sciencedirect.com www.sciencedirect.com
    RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development
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      DOI: 10.1016/j.cell.2021.10.016

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    sciencedirect.com/science/article/pii/S0092867421012320
  135. Oct 2021
  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuronal ribosomes exhibit dynamic and context-dependent exchange of ribosomal proteins
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      DOI: 10.1038/s41467-021-26365-x

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  137. www.sciencedirect.com www.sciencedirect.com
    Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation
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      DOI: 10.1016/j.celrep.2021.109899

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  138. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Protein Kinase D promotes activity-dependent AMPA receptor endocytosis in hippocampal neurons
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      DOI: 10.1111/tra.12819

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  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activity-dependent modulation of synapse-regulating genes in astrocytes
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      DOI: 10.7554/eLife.70514

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  140. www.sciencedirect.com www.sciencedirect.com
    Temporally distinct post-replicative repair mechanisms fill PRIMPOL-dependent ssDNA gaps in human cells
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      DOI: 10.1016/j.molcel.2021.09.013

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  141. Sep 2021
  142. www.sciencedirect.com www.sciencedirect.com
    An additional NF-κB site allows HIV-1 subtype C to evade restriction by nuclear PYHIN proteins
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      DOI: 10.1016/j.celrep.2021.109735

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    Long-term depression links amyloid-β to the pathological hyperphosphorylation of tau
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  144. Aug 2021
  145. www.sciencedirect.com www.sciencedirect.com
    Dynamic bi-directional phosphorylation events associated with the reciprocal regulation of synapses during homeostatic up- and down-scaling
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      DOI: 10.1016/j.celrep.2021.109583

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  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A CTP-dependent gating mechanism enables ParB spreading on DNA
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      DOI: 10.7554/eLife.69676

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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin and Candida stimulation
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Maternally inherited piRNAs direct transient heterochromatin formation at active transposons during early Drosophila embryogenesis
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      DOI: 10.7554/eLife.68573

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  149. www.sciencedirect.com www.sciencedirect.com
    PGC1α is required for the renoprotective effect of lncRNA Tug1 in vivo and links Tug1 with urea cycle metabolites
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      DOI: 10.1016/j.celrep.2021.109510

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    Reconstitution of the destruction complex defines roles of AXIN polymers and APC in β-catenin capture, phosphorylation, and ubiquitylation
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    DHA and its derived lipid mediators MaR1, RvD1 and RvD2, block TNF-α inhibition of intestinal sugar and glutamine uptake in Caco-2 cells
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      DOI: 10.1016/j.jnutbio.2019.108264

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  152. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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      DOI: 10.1002/cne.23945

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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oxaliplatin resistance in colorectal cancer enhances TRAIL sensitivity via death receptor 4 upregulation and lipid raft localization
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      DOI: 10.7554/eLife.67750

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  154. Jul 2021
  155. elifesciences.org elifesciences.org
    Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72
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  156. elifesciences.org elifesciences.org
    Rare missense variants in the human cytosolic antibody receptor preserve antiviral function
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    RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer
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    A novel small molecule supports the survival of cultured dopamine neurons and may restore the dopaminergic innervation of the brain in the MPTP mouse model of Parkinson's disease
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    ATG5 cancer mutations and alternative mRNA splicing reveal a conjugation switch that regulates ATG12–ATG5-ATG16L1 complex assembly and autophagy
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    Reconstitution of Microtubule Nucleation In Vitro Reveals Novel Roles for Mzt1
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    USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication
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    Differentiation of adipose-derived stem cells to functional CD105<Superscript>neg</Superscript> CD73<Superscript>low</Superscript> melanocyte precursors guided by defined culture condition
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    Role of a conserved glutamine in the function of voltage-gated Ca2+ channels revealed by a mutation in human CACNA1D
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    Placental effects and transfer of sildenafil in healthy and preeclamptic conditions
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    Microtubule Tip Tracking by the Spindle and Kinetochore Protein Ska1 Requires Diverse Tubulin-Interacting Surfaces
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    Activity-Dependent Remodeling of Drosophila Olfactory Sensory Neuron Brain Innervation during an Early-Life Critical Period
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    Metabolic Abnormalities of Chronic High-Dose Glucocorticoids Are Not Mediated by Hypothalamic AgRP in Male Mice
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    Obesity Decreases Hepatic 25‐Hydroxylase Activity Causing Low Serum 25‐Hydroxyvitamin D
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    CTP regulates membrane-binding activity of the nucleoid occlusion protein Noc
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    Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis
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    Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination
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    Leucine Carboxyl Methyltransferase 1 Overexpression Protects Against Cognitive and Electrophysiological Impairments in Tg2576 APP Transgenic Mice
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    PPP2R4 dysfunction promotes KRAS-mutant lung adenocarcinoma development and mediates opposite responses to MEK and mTOR inhibition
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  176. Jun 2021
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    Identification of an atypical interaction site in the BTB domain of the MYC-interacting zinc-finger protein 1
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    Identification and validation of selective deubiquitinase inhibitors
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    Neuromuscular junction instability and altered intracellular calcium handling as early determinants of force loss during unloading in humans
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  180. May 2021
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    Toxoplasma gondii secreted effectors co-opt host repressor complexes to inhibit necroptosis
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    Gene-environment interactions mediate stress susceptibility and resilience through the CaMKIIβ/TARPγ-8/AMPAR pathway
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    Divergent and self-reactive immune responses in the CNS of COVID-19 patients with neurological symptoms
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    TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation
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    Reciprocal communication between astrocytes and endothelial cells is required for astrocytic glutamate transporter 1 (GLT-1) expression
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    Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation
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    COR758, a negative allosteric modulator of GABAB receptors
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  191. Mar 2021
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    Dynamic interactions between the RNA chaperone Hfq, small regulatory RNAs, and mRNAs in live bacterial cells
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    Parkin is an E3 ligase for the ubiquitin-like modifier FAT10, which inhibits Parkin activation and mitophagy
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    Astrocyte-derived small extracellular vesicles promote synapse formation via fibulin-2-mediated TGF-β signaling
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  196. Feb 2021
  197. elifesciences.org elifesciences.org
    Deleting Mecp2 from the cerebellum rather than its neuronal subtypes causes a delay in motor learning in mice
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    Dimerisation of the PICTS complex via LC8/Cut-up drives co-transcriptional transposon silencing in Drosophila
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  199. Jan 2021
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    G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling
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    Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution
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    TREX2 Exonuclease Causes Spontaneous Mutations and Stress-Induced Replication Fork Defects in Cells Expressing RAD51K133A
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    Ablation of Fat Cells in Adult Mice Induces Massive Bone Gain
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    An epilepsy‐associated ACTL6B variant captures neuronal hyperexcitability in a human induced pluripotent stem cell model
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    Reduced expression of the PP2A methylesterase, PME-1, or the PP2A methyltransferase, LCMT-1, alter sensitivity to beta-amyloid induced cognitive and electrophysiological impairments in mice
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    Nef-Mediated CD3-TCR Downmodulation Dampens Acute Inflammation and Promotes SIV Immune Evasion
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    Altered Sexual Behavior in Dopamine Transporter (DAT) Knockout Male Rats: A Behavioral, Neurochemical and Intracerebral Microdialysis Study
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    Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions
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    Endolysosomal Targeting of Mitochondria Is Integral to BAX-Mediated Mitochondrial Permeabilization during Apoptosis Signaling
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    Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum
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    Complexin Suppresses Spontaneous Exocytosis by Capturing the Membrane-Proximal Regions of VAMP2 and SNAP25
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    Transcriptional Regulation of the Glutamate/GABA/Glutamine Cycle in Adult Glia Controls Motor Activity and Seizures in Drosophila
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    Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling
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    DHA and its derived lipid mediators MaR1, RvD1 and RvD2, block TNF-α inhibition of intestinal sugar and glutamine uptake in Caco-2 cells
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    PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells
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    Lovastatin, not Simvastatin, Corrects Core Phenotypes in the Fragile X Mouse Model
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    Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses
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    Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection
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    IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation
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    Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells
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    Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Modulates Lifespan
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    Pyk2 Signaling through Graf1 and RhoA GTPase Is Required for Amyloid-β Oligomer-Triggered Synapse Loss
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    A Chaperone Lid Ensures Efficient and Privileged Client Transfer during Tail-Anchored Protein Targeting
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  242. Nov 2018
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    The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment
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    A Short Tandem Repeat-Enriched RNA Assembles a Nuclear Compartment to Control Alternative Splicing and Promote Cell Survival
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    Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage
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    Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A
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    Mitochondrial DNA Variation Dictates Expressivity and Progression of Nuclear DNA Mutations Causing Cardiomyopathy
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    1. scibot 05 Nov 2018
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      Curator: @Jmenke

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      SciCrunch record: RRID:SCR_013715

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:SCR_013715 RRIDCUR:Missing
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