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446 Matching Annotations

Oct 2023
dx.doi.org dx.doi.org

Chromatin accessibility landscape of human triple-negative breast cancer cell lines reveals variation by patient donor ancestry

1
1. scibot 06 Oct 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1158/2767-9764.CRC-23-0236
  
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dx.doi.org/10.1158/2767-9764.CRC-23-0236
www.nature.com www.nature.com

TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression

1
1. scibot 06 Oct 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1038/s41467-023-41927-x
  
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nature.com/articles/s41467-023-41927-x
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Acquisition of Neural Fate by Combination of BMP Blockade and Chromatin Modification

1
1. scibot 06 Oct 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1016/j.isci.2023.107887
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10522999/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Chromosome-level reference genome of tetraploid Isoetes sinensis provides insights into evolution and adaption of lycophytes

1
1. scibot 05 Oct 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1093/gigascience/giad079
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10541799/
Sep 2023
52.53.155.43 52.53.155.43

jkad203-html.html

1
1. scibot 22 Sep 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1093/g3journal/jkad203
  
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52.53.155.43/213eef494e744243d5c25ee25ef9fbca7c526326/jkad203-html.html
dx.doi.org dx.doi.org

Targeting KDM2A Enhances T Cell Infiltration in NSD1-Deficient Head and Neck Squamous Cell Carcinoma

1
1. scibot 15 Sep 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1158/0008-5472.CAN-22-3114
  
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dx.doi.org/10.1158/0008-5472.CAN-22-3114
Aug 2023
www.biorxiv.org www.biorxiv.org

Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3’ UTR of FAIM2

1
1. scibot 27 Aug 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1101/2023.08.21.553157
  
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biorxiv.org/content/10.1101/2023.08.21.553157v1
52.53.155.43 52.53.155.43

Aberrant accumulation of Kras-dependent pervasive transcripts during tumor progression renders cancer cells dependent on PAF1 expression

2
1. scibot 16 Aug 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1016/j.celrep.2023.112979
  
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2. scibot 16 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112979
  
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52.53.155.43/491f3628ae56ca418965e7c0fc6856d1761b345d/PIIS2211124723009907-html.html
52.53.155.43 52.53.155.43

SnakeMAGs: a simple, efficient, flexible and scalable workflow to reconstruct prokaryotic genomes from metagenomes

1
1. scibot 12 Aug 2023
  
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  RRID:SCR_016368
  
  DOI: 10.12688/f1000research.128091.1
  
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52.53.155.43/fa09bfb21d5dc9f1bb74c50683a5c7a2d8f74864/c9952df4-51f9-40f3-b822-30ae2a3528b7_128091_-_vincent_herve-html.html
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Proteasome Inhibition Sensitizes Liposarcoma to MDM2 Inhibition with Nutlin-3 by Activating the ATF4/CHOP Stress Response Pathway

1
1. scibot 03 Aug 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1158/0008-5472.CAN-22-3173
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10391328/
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Deficiency of the Polycomb protein RYBP and TET methylcytosine oxidases promotes extensive CpG island hypermethylation and malignant transformation

1
1. scibot 03 Aug 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1158/0008-5472.CAN-23-0269
  
  Resource: Bowtie (RRID:SCR_005476)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10391329/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Longitudinal map of transcriptome changes in the Lyme pathogen Borrelia burgdorferi during tick-borne transmission

1
1. scibot 03 Aug 2023
  
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  RRID:SCR_016368
  
  DOI: 10.7554/eLife.86636
  
  Resource: Bowtie (RRID:SCR_005476)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10393048/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Histone variants shape chromatin states in Arabidopsis

1
1. scibot 03 Aug 2023
  
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  RRID:SCR_016368
  
  DOI: 10.7554/eLife.87714
  
  Resource: Bowtie (RRID:SCR_005476)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10393023/
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming

1
1. scibot 27 Jul 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1016/j.isci.2023.107231
  
  Resource: Bowtie (RRID:SCR_005476)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10366467/
www.sciencedirect.com www.sciencedirect.com

Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation

1
1. scibot 27 Jul 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1016/j.devcel.2023.07.001
  
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sciencedirect.com/science/article/pii/S1534580723003313
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Evolutionary history of Staphylococcus aureus influences antibiotic resistance evolution

1
1. scibot 27 Jul 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1016/j.cub.2023.06.082
  
  Resource: Bowtie (RRID:SCR_005476)
  
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sciencedirect.com/science/article/pii/S0960982223008680
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Bacterial clade-specific analysis identifies distinct epithelial responses in inflammatory bowel disease

1
1. scibot 25 Jul 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1016/j.xcrm.2023.101124
  
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sciencedirect.com/science/article/pii/S2666379123002525
52.53.155.43 52.53.155.43

A clinical metagenomic study of biopsies from Mexican endophthalmitis patients reveals the presence of complex bacterial communities and a diversity of resistance genes

1
1. scibot 15 Jul 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1099/acmi.0.000639.v1
  
  Resource: Bowtie (RRID:SCR_005476)
  
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52.53.155.43/65c508bb478a3b25f02108e2427b3135ab529330/acmi.0.000639.v1-html.html
www.sciencedirect.com www.sciencedirect.com

Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer

1
1. scibot 14 Jul 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1016/j.xcrm.2023.101120
  
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sciencedirect.com/science/article/pii/S2666379123002483
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

An initial genomic blueprint of the healthy human oesophageal microbiome

1
1. scibot 08 Jul 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1099/acmi.0.000558.v3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10323806/
52.53.155.43 52.53.155.43

can-23-0269-html.html

1
1. scibot 08 Jul 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1158/0008-5472.can-23-0269
  
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52.53.155.43/54e62d316063b1626eedcc4063c6657fd4e230c9/can-23-0269-html.html
52.53.155.43 52.53.155.43

can-22-3173-html.html

1
1. scibot 08 Jul 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1158/0008-5472.can-22-3173
  
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52.53.155.43/7a07162d3285902b20a1a359628fdd8826284ee8/can-22-3173-html.html
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Genome assembly of the hybrid grapevine Vitis ‘Chambourcin’

1
1. scibot 06 Jul 2023
  
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  RRID:SCR_016368
  
  DOI: 10.46471/gigabyte.84
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10318349/
Jun 2023
52.53.155.43 52.53.155.43

can-22-3173-html.html

1
1. scibot 30 Jun 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1158/0008-5472.CAN-22-3173
  
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52.53.155.43/7a07162d3285902b20a1a359628fdd8826284ee8/can-22-3173-html.html
52.53.155.43 52.53.155.43

can-22-2712-html.html

1
1. scibot 29 Jun 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1158/0008-5472.CAN-22-2712
  
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52.53.155.43/726555d37fadfa1ef429cf94df3437d3f13c8b94/can-22-2712-html.html
www.embopress.org www.embopress.org

DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres

1
1. scibot 22 Jun 2023
  
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  RRID:SCR_016368
  
  DOI: 10.15252/embr.202256492
  
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embopress.org/doi/10.15252/embr.202256492
52.53.155.43 52.53.155.43

Modelling host-Trypanosoma brucei gambiense interactions in vitro using human induced pluripotent stem cell-derived cortical brain organoids

1
1. scibot 10 Jun 2023
  
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  RRID:SCR_016368
  
  DOI: 10.12688/f1000research.131507.1
  
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  Curator: @anisehay
  
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52.53.155.43/e625996f46e0c62f511495ba188f0d844b09baec/25e3f246-e807-4cca-936d-1d5d935cdca0_131507_-_juan_quintana-html.html
aacrjournals.org aacrjournals.org

(R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers

1
1. scibot 10 Jun 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1158/2159-8290.CD-22-0825
  
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aacrjournals.org/cancerdiscovery/article/13/6/1478/726967/R-2-Hydroxyglutarate-Inhibits-KDM5-Histone-Lysine
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Comparative analysis of microRNA expression profiles in shoot and root tissues of contrasting rice cultivars (Oryza sativa L.) with different salt stress tolerance

1
1. scibot 27 May 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1371/journal.pone.0286140
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10208480/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Developmental dynamics of chromatin accessibility during post-implantation development of monkey embryos

1
1. scibot 27 May 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1093/gigascience/giad038
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10209733/
52.53.155.43 52.53.155.43

bqad083-html.html

1
1. scibot 27 May 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1210/endocr/bqad083
  
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52.53.155.43/c24202ba5c1e462601cd87eadcb0082575e1cb0e/bqad083-html.html
www.sciencedirect.com www.sciencedirect.com

Bat ASC2 suppresses inflammasomes and ameliorates inflammatory diseases

1
1. scibot 12 May 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1016/j.cell.2023.03.036
  
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  Curator: @sofiakhan13
  
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sciencedirect.com/science/article/pii/S0092867423003331
onlinelibrary.wiley.com onlinelibrary.wiley.com

KMT2D Deficiency Promotes Myeloid Leukemias which Is Vulnerable to Ribosome Biogenesis Inhibition

1
1. scibot 10 May 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1002/advs.202206098
  
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onlinelibrary.wiley.com/doi/10.1002/advs.202206098
www.biorxiv.org www.biorxiv.org

L1 retrotransposons drive human neuronal transcriptome complexity and functional diversification

1
1. scibot 04 May 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1101/2023.03.04.531072
  
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biorxiv.org/content/10.1101/2023.03.04.531072v1
Apr 2023
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A hyper-quiescent chromatin state formed during aging is reversed by regeneration

1
1. scibot 29 Apr 2023
  
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  RRID:SCR_016368
  
  DOI: 10.1016/j.molcel.2023.04.005
  
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Maternal and food microbial sources shape the infant microbiome of a rural Ethiopian population

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Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis

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Novel enhancers conferring compensatory transcriptional regulation of Nkx2-5 in heart development

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INTAC endonuclease and phosphatase modules differentially regulate transcription by RNA polymerase II

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Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload

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Asparagine starvation suppresses histone demethylation through iron depletion

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Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting

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Atria: an ultra-fast and accurate trimmer for adapter and quality trimming

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Genome assembly of the roundjaw bonefish (Albula glossodonta), a vulnerable circumtropical sportfish

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Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion

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SnakeMAGs: a simple, efficient, flexible and scalable workflow to reconstruct prokaryotic genomes from metagenomes

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MeCP2 regulates Gdf11, a dosage-sensitive gene critical for neurological function

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Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eye

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A chromosome-scale draft genome sequence of horsegram (Macrotyloma uniflorum)

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Genome assembly of the numbat (Myrmecobius fasciatus), the only termitivorous marsupial

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Human hematopoietic stem cell vulnerability to ferroptosis

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The BRD4 inhibitor JQ1 augments the antitumor efficacy of abemaciclib in preclinical models of gastric carcinoma

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DDR2 coordinates EMT and metabolic reprogramming as a shared effector of FOXQ1 and SNAI1

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Enrichment of oral-derived bacteria in inflamed colorectal tumors and distinct associations of Fusobacterium in the mesenchymal subtype

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Genomic view of the diversity and functional role of archaea and bacteria in the skeleton of the reef-building corals Porites lutea and Isopora palifera

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Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors

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A chromosome-scale assembly for tetraploid sour cherry (Prunus cerasus L.) ‘Montmorency’ identifies three distinct ancestral Prunus genomes

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Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers

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Resistance to white spot syndrome virus in the European shore crab is associated with suppressed virion trafficking and heightened immune responses

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SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis

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PRC2 Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1 Targeted Therapy via Enhanced Viral Mimicry

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Dec 2022
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Targeting metabolic adaptations in the breast cancer–liver metastatic niche using dietary approaches to improve endocrine therapy efficacy

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BAF complex maintains glioma stem cells in pediatric H3K27M-glioma

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Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation

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Transcriptomic Correlates of Tumor Cell PD-L1 Expression and Response to Nivolumab Monotherapy in Metastatic Clear Cell Renal Cell Carcinoma

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Essential role of MESP1-RING1A complex in cardiac differentiation

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DDR2 Coordinates EMT and Metabolic Reprogramming as a Shared Effector of FOXQ1 and SNAI1

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aacrjournals.org/cancerrescommun/article/2/11/1388/710518/DDR2-Coordinates-EMT-and-Metabolic-Reprogramming
academic.oup.com academic.oup.com

High-quality genome assembles from key Hawaiian coral species

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  DOI: 10.1093/gigascience/giac098
  
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academic.oup.com/gigascience/article/doi/10.1093/gigascience/giac098/6815755
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Transcription factor antagonism regulates heterogeneity in embryonic stem cell states

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Oct 2022
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CircIPO7 Promotes Nasopharyngeal Carcinoma Metastasis and Cisplatin Chemoresistance by Facilitating YBX1 Nuclear Localization

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  DOI: 10.1158/1078-0432.CCR-22-0991
  
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RNA-binding protein Elavl1/HuR is required for maintenance of cranial neural crest specification

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  DOI: 10.7554/eLife.63600
  
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A cis-regulatory lexicon of DNA motif combinations mediating cell-type-specific gene regulation

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Dicer1 deficient mice exhibit premature ageing and metabolic perturbations in adipocytes

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PU.1-dependent enhancer inhibition separates Tet2-deficient hematopoiesis from malignant transformation

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In Vivo Genome-Wide CRISPR Activation Screening Identifies Functionally Important Long Noncoding RNAs in Hepatocellular Carcinoma

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Genomic analysis reveals cryptic diversity in aphelids and sheds light on the emergence of Fungi

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Acquired semi-squamatization during chemotherapy suggests differentiation as a therapeutic strategy for bladder cancer

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Loss of key endosymbiont genes may facilitate early host control of the chromatophore in Paulinella

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STAG2 promotes the myelination transcriptional program in oligodendrocytes

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The human mitochondrial genome contains a second light strand promoter

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Intracellular cholesterol pools regulate oncogenic signaling and epigenetic circuitries in Early T-cell Precursor Acute Lymphoblastic Leukemia

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Npas3 deficiency impairs cortical astrogenesis and induces autistic-like behaviors

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Losartan blocks osteosarcoma-elicited monocyte recruitment, and combined with the kinase inhibitor toceranib, exerts significant clinical benefit in canine metastatic osteosarcoma

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LncRNA and mRNA expression profiles in brown adipose tissue of obesity-prone and obesity-resistant mice

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TOP1 CAD-seq: A protocol to map catalytically engaged topoisomerase 1 in human cells

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EGFR signaling activates intestinal stem cells by promoting mitochondrial biogenesis and β-oxidation

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A chromosome-level genome assembly and intestinal transcriptome of Trypoxylus dichotomus (Coleoptera: Scarabaeidae) to understand its lignocellulose digestion ability

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Bacterial growth in multicellular aggregates leads to the emergence of complex life cycles

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Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors

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Porcupine inhibition disrupts mitochondrial function and homeostasis in WNT ligand-addicted pancreatic cancer

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Dnmt3a knockout in excitatory neurons impairs postnatal synapse maturation and increases the repressive histone modification H3K27me3

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Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine

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JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation

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Mapping cis-regulatory elements in human neurons links psychiatric disease heritability and activity-regulated transcriptional programs

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Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion

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A Whole Transcriptome Analysis in Peripheral Blood Suggests That Energy Metabolism and Inflammation Are Involved in Major Depressive Disorder

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A chromosome-level reference genome of Ensete glaucum gives insight into diversity and chromosomal and repetitive sequence evolution in the Musaceae

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RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex

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An adult-stage transcriptional program for survival of serotonergic connectivity

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HNF4A modulates glucocorticoid action in the liver

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Chromosome-level genome of the globe skimmer dragonfly (Pantala flavescens)

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A high-quality assembled genome and its comparative analysis decode the adaptive molecular mechanism of the number one Chinese cotton variety CRI-12

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Presence of H3K4me3 on Paternally Expressed Genes of the Paternal Genome From Sperm to Implantation

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Mar 2022
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Novel insights from a multiomics dissection of the Hayflick limit

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Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit

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A test of the pioneer factor hypothesis using ectopic liver gene activation

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ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma

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Fully resolved assembly of Cryptosporidium parvum

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Identification of new ETV6 modulators through a high throughput functional screening

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  DOI: 10.1016/j.isci.2022.103858
  
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Simultaneous cellular and molecular phenotyping of embryonic mutants using single-cell regulatory trajectories

1
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Uncovering the mesendoderm gene regulatory network through multi-omic data integration

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Systematic analysis of naturally occurring insertions and deletions that alter transcription factor spacing identifies tolerant and sensitive transcription factor pairs

1
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Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration

1
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Multimodal regulatory elements within a hormone-specific super enhancer control a heterogeneous transcriptional response

1
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Construction of Strand-seq libraries in open nanoliter arrays

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  DOI: 10.1016/j.crmeth.2021.100150
  
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Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells

1
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MAP3K7 loss drives enhanced androgen signaling and independently confers risk of recurrence in prostate cancer with joint loss of CHD1

2
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Wnt signaling mediates acquisition of blood–brain barrier properties in naïve endothelium derived from human pluripotent stem cells

1
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MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”

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Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis

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SOX9 Defines Distinct Populations of Cells in SHH Medulloblastoma but Is Not Required for Math1-Driven Tumor Formation

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CHD5 inhibits metastasis of neuroblastoma

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  DOI: 10.1038/s41388-021-02081-0
  
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Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1

1
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Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis

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Sequence features of retrotransposons allow for epigenetic variability

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Kr-h1 maintains distinct caste-specific neurotranscriptomes in response to socially regulated hormones

1
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Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells

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Induced intra- and intermolecular template switching as a therapeutic mechanism against RNA viruses

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Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers

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Clinical Significance of Circulating Tumor Cell Induced Epithelial-Mesenchymal Transition in Patients with Metastatic Colorectal Cancer by Single-Cell RNA-Sequencing

1
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A chromosome-level genome assembly for the eastern fence lizard (Sceloporus undulatus), a reptile model for physiological and evolutionary ecology

1
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Acrylamide modulates the mouse epididymal proteome to drive alterations in the sperm small non-coding RNA profile and dysregulate embryo development

1
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Global chromatin relabeling accompanies spatial inversion of chromatin in rod photoreceptors

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  DOI: 10.1126/sciadv.abj3035
  
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Tiled-ClickSeq for targeted sequencing of complete coronavirus genomes with simultaneous capture of RNA recombination and minority variants

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Global chromatin relabeling accompanies spatial inversion of chromatin in rod photoreceptors

1
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Monocytic differentiation and AHR signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia

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H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity

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SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling

1
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Leveraging the Mendelian disorders of the epigenetic machinery to systematically map functional epigenetic variation

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Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway

1
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SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape

1
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KLF10 integrates circadian timing and sugar signaling to coordinate hepatic metabolism

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An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens

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Transcriptional control of brain tumor stem cells by a carbohydrate binding protein

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Conditional stomatal closure in a fern shares molecular features with flowering plant active stomatal responses

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Cis-regulatory variants affect gene expression dynamics in yeast

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NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1

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Heterochromatin-dependent transcription of satellite DNAs in the Drosophila melanogaster female germline

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CLOCKWORK ORANGE promotes CLOCK-CYCLE activation via the putative Drosophila ortholog of CLOCK INTERACTING PROTEIN CIRCADIAN

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Untitled document

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Transcriptional Burst Initiation and Polymerase Pause Release Are Key Control Points of Transcriptional Regulation

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Intrinsic Dynamics of a Human Gene Reveal the Basis of Expression Heterogeneity

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Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia

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Iruka Eliminates Dysfunctional Argonaute by Selective Ubiquitination of Its Empty State

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IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation

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Gain of CTCF-Anchored Chromatin Loops Marks the Exit from Naive Pluripotency

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Deregulated Expression of Mammalian lncRNA through Loss of SPT6 Induces R-Loop Formation, Replication Stress, and Cellular Senescence

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Acetylation of Cytidine in mRNA Promotes Translation Efficiency

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Widespread Enhancer Dememorization and Promoter Priming during Parental-to-Zygotic Transition

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A B-Cell-Specific Enhancer Orchestrates Nuclear Architecture to Generate a Diverse Antigen Receptor Repertoire

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Spatiotemporal m(i)RNA Architecture and 3′ UTR Regulation in the C. elegans Germline

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Higher-Order Organization Principles of Pre-translational mRNPs

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Exon Junction Complex Shapes the Transcriptome by Repressing Recursive Splicing

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Exon Junction Complexes Suppress Spurious Splice Sites to Safeguard Transcriptome Integrity

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N6-methyladenine DNA Modification in Glioblastoma

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An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis

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Plant-Derived Exosomal MicroRNAs Shape the Gut Microbiota

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SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcing Distinct Chromatin States

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Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin

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A hybrid de novo assembly of the sea pansy (Renilla muelleri) genome

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Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening

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ZNRF3 and RNF43 cooperate to safeguard metabolic liver zonation and hepatocyte proliferation

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The genome of the venomous snail Lautoconus ventricosus sheds light on the origin of conotoxin diversity

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Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist

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Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver

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Neural Stem Cells Direct Axon Guidance via Their Radial Fiber Scaffold

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Repeated introductions and intensive community transmission fueled a mumps virus outbreak in Washington State

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Developmentally Programmed Tankyrase Activity Upregulates β-Catenin and Licenses Progression of Embryonic Genome Activation

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Evidence for additive and synergistic action of mammalian enhancers during cell fate determination

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Inducible mechanisms of disease tolerance provide an alternative strategy of acquired immunity to malaria

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Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma

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Developmental hourglass and heterochronic shifts in fin and limb development

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Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia

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The unique composition of Indian gut microbiome, gene catalogue, and associated fecal metabolome deciphered using multi-omics approaches

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New de novo assembly of the Atlantic bottlenose dolphin (Tursiops truncatus) improves genome completeness and provides haplotype phasing

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