303 Matching Annotations
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    Detection of ac4C in human mRNA is preserved upon data reassessment
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    1. scibot 20 Apr 2024
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      DOI: 10.1016/j.molcel.2024.03.018

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    sciencedirect.com/science/article/pii/S1097276524002284
  3. Apr 2024
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    Dual-role transcription factors stabilize intermediate expression levels
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      DOI: 10.1016/j.cell.2024.03.023

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    sciencedirect.com/science/article/pii/S0092867424003143
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    PALB2-mutated human mammary cells display a broad spectrum of morphological and functional abnormalities induced by increased TGFβ signaling
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    1. scibot 13 Apr 2024
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      DOI: 10.1007/s00018-024-05183-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11006627/
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    EP300/CREBBP acetyltransferase inhibition limits steroid receptor and FOXA1 signaling in prostate cancer cells
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      DOI: 10.1007/s00018-024-05209-z

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    A senescence restriction point acting on chromatin integrates oncogenic signals
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    1. scibot 04 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724003723
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    Telomere dysfunction alters intestinal stem cell dynamics to promote cancer
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    1. scibot 04 Apr 2024
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    sciencedirect.com/science/article/pii/S1534580724001886
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    Analysis of several common APOBEC-type mutations in bladder tumors suggests links to viral infection
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      DOI: 10.1158/1940-6207.CAPR-23-0112

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    ncbi.nlm.nih.gov/pmc/articles/PMC10592262/
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    Select EZH2 inhibitors enhance viral mimicry effects of DNMT inhibition through a mechanism involving NFAT:AP-1 signaling
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    1. scibot 03 Apr 2024
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      DOI: 10.1126/sciadv.adk4423

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    ncbi.nlm.nih.gov/pmc/articles/PMC10971413/
  11. Mar 2024
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    Immune dysfunction mediated by the competitive endogenous RNA network in fetal side placental tissue of polycystic ovary syndrome
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      DOI: 10.1371/journal.pone.0300461

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    ncbi.nlm.nih.gov/pmc/articles/PMC10956758/
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    Peripheral neuronal activation shapes the microbiome and alters gut physiology
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    sciencedirect.com/science/article/pii/S221112472400281X
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    From degraded to deciphered: ATAC-seq’s application potential in forensic diagnosis
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    1. scibot 19 Mar 2024
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      DOI: 10.1007/s00414-024-03206-2

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    A Cluster of Evolutionarily Recent KRAB Zinc Finger Proteins Protects Cancer Cells from Replicative Stress-Induced Inflammation
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    1. scibot 17 Mar 2024
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      DOI: 10.1158/0008-5472.CAN-23-1237

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    ncbi.nlm.nih.gov/pmc/articles/PMC10940857/
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    CD8+ T cell memory induced by successive SARS-CoV-2 mRNA vaccinations is characterized by shifts in clonal dominance
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    sciencedirect.com/science/article/pii/S2211124724002158
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    The transcription factor NF-κB orchestrates nucleosome remodeling during the primary response to Toll-like receptor 4 signaling
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    1. scibot 05 Mar 2024
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      DOI: 10.1016/j.immuni.2024.02.004

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    Treatment response in first-line metastatic pancreatic ductal adenocarcinoma is stratified by a composite index of tumor proliferation and CD8 T cell infiltration
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      DOI: 10.1158/1078-0432.CCR-23-0535

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    ncbi.nlm.nih.gov/pmc/articles/PMC10530235/
  19. Feb 2024
  20. 52.53.155.43 52.53.155.43
    Transcriptional response of the heart to vagus nerve stimulation
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      DOI: 10.1152/physiolgenomics.00095.2023

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      DOI: 10.1152/physiolgenomics.00095.2023

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    52.53.155.43/1d74c7a9de06d0c8fd1f9db4b510dc74e1613524/kellett-et-al-2024-transcriptional-response-of-the-heart-to-vagus-nerve-stimulation-html.html
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    Cell-type-specific expression of tRNAs in the brain regulates cellular homeostasis
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    1. scibot 21 Feb 2024
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      DOI: 10.1016/j.neuron.2024.01.028

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    sciencedirect.com/science/article/pii/S0896627324000540
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    SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway
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    1. scibot 16 Feb 2024
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    sciencedirect.com/science/article/pii/S1534580724000443
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    A Mutation-driven oncofetal regression fuels phenotypic plasticity in colorectal cancer
    1
    1. scibot 09 Feb 2024
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      DOI: 10.1101/2023.12.10.570854

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    biorxiv.org/content/10.1101/2023.12.10.570854v1
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    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer
    1
    1. scibot 07 Feb 2024
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      DOI: 10.1186/s13059-023-03161-y

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    Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas
    1
    1. scibot 06 Feb 2024
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      DOI: 10.1158/2159-8290.CD-22-1401

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    ncbi.nlm.nih.gov/pmc/articles/PMC10524254/
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    Microglia maintain structural integrity during fetal brain morphogenesis
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    1. scibot 06 Feb 2024
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    PHF6 suppresses self-renewal of leukemic stem cells in AML
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    ncbi.nlm.nih.gov/pmc/articles/PMC10802281/
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    Development of sexual dimorphism of skeletal muscles through the adrenal cortex, caused by androgen-induced global gene suppression
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    sciencedirect.com/science/article/pii/S2211124724000433
  29. Jan 2024
  30. www.sciencedirect.com www.sciencedirect.com
    5-Hydroxymethylcytosine signals in serum are a predictor of chemoresistance in high-grade serous ovarian cancer
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    sciencedirect.com/science/article/pii/S0090825824000015
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRDM3/16 Regulate Chromatin Accessibility Required for NKX2-1 Mediated Alveolar Epithelial Differentiation and Function
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      DOI: 10.1101/2023.12.20.570481

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    Inherited blood cancer predisposition through altered transcription elongation
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  33. dx.doi.org dx.doi.org
    Early microbial intervention reshapes phenotypes of newborn Bos taurus through metabolic regulations
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      DOI: 10.1093/gigascience/giad118

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    dx.doi.org/10.1093/gigascience/giad118
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    β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer
    1
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      DOI: 10.1158/0008-5472.CAN-22-2712

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    ncbi.nlm.nih.gov/pmc/articles/PMC10330305/
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    Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
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      DOI: 10.1016/j.cmet.2023.12.010

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    sciencedirect.com/science/article/pii/S1550413123004618
  36. Dec 2023
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    Pluripotency state transition of embryonic stem cells requires the turnover of histone chaperone FACT on chromatin
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      DOI: 10.1016/j.isci.2023.108537

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    sciencedirect.com/science/article/pii/S2589004223026147
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    Glucose stress causes mRNA retention in nuclear Nab2 condensates
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      DOI: 10.1016/j.celrep.2023.113593

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    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S1535610823004014
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis
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      DOI: 10.1038/s41467-023-43751-9

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  41. www.science.org www.science.org
    A single-cell multi-omic atlas spanning the adult rhesus macaque brain
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      DOI: 10.1126/sciadv.adh1914

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    science.org/doi/10.1126/sciadv.adh1914
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    Genetic swamping of the critically endangered Scottish wildcat was recent and accelerated by disease
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      DOI: 10.1016/j.cub.2023.10.026

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    sciencedirect.com/science/article/pii/S0960982223014240
  43. www.biorxiv.org www.biorxiv.org
    Genome organization regulates nuclear pore complex formation and promotes differentiation during Drosophila oogenesis
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      DOI: 10.1101/2023.11.15.567233

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    biorxiv.org/content/10.1101/2023.11.15.567233v1
  44. www.biorxiv.org www.biorxiv.org
    A nuclear architecture screen in Drosophila identifies Stonewall as a link between chromatin position at the nuclear periphery and germline stem cell fate
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      DOI: 10.1101/2023.11.17.567611

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    biorxiv.org/content/10.1101/2023.11.17.567611v1
  45. Nov 2023
  46. www.sciencedirect.com www.sciencedirect.com
    Genomic and transcriptomic characterization of delta SARS-CoV-2 infection in free-ranging white-tailed deer (Odocoileus virginianus)
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      DOI: 10.1016/j.isci.2023.108319

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  47. www.nature.com www.nature.com
    Selective inhibition of CDK9 in triple negative breast cancer
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      DOI: 10.1038/s41388-023-02892-3

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    Repression of LSD1 potentiates homologous recombination-proficient ovarian cancer to PARP inhibitors through down-regulation of BRCA1/2 and RAD51
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    LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
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    Broodstock nutritional programming differentially affects the hepatic transcriptome and genome-wide DNA methylome of farmed gilthead sea bream (Sparus aurata) depending on genetic background
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    Oral vancomycin treatment suppresses gut trypsin activity and preserves intestinal barrier function during EAE
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    Zinc Finger MYND-Type Containing 8 (ZMYND8) is epigenetically regulated in mutant Isocitrate Dehydrogenase 1 (IDH1) glioma to promote radioresistance
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    Tissue-specific and tissue-agnostic effects of genome sequence variation modulating blood pressure
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    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
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    Molecular and functional characterization of the Drosophila melanogaster conserved smORFome
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    Loss of succinyl-CoA synthetase in mouse forebrain results in hypersuccinylation with perturbed neuronal transcription and metabolism
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    Three-dimensional genome architecture coordinates key regulators of lineage specification in mammary epithelial cells
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    Oncogenic context shapes the fitness landscape of tumor suppression
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    Chromatin accessibility landscape of human triple-negative breast cancer cell lines reveals variation by patient donor ancestry
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    TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression
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    Acquisition of Neural Fate by Combination of BMP Blockade and Chromatin Modification
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    Chromosome-level reference genome of tetraploid Isoetes sinensis provides insights into evolution and adaption of lycophytes
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    Targeting KDM2A Enhances T Cell Infiltration in NSD1-Deficient Head and Neck Squamous Cell Carcinoma
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  70. Aug 2023
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    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3’ UTR of FAIM2
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    Aberrant accumulation of Kras-dependent pervasive transcripts during tumor progression renders cancer cells dependent on PAF1 expression
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    SnakeMAGs: a simple, efficient, flexible and scalable workflow to reconstruct prokaryotic genomes from metagenomes
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    Proteasome Inhibition Sensitizes Liposarcoma to MDM2 Inhibition with Nutlin-3 by Activating the ATF4/CHOP Stress Response Pathway
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    Deficiency of the Polycomb protein RYBP and TET methylcytosine oxidases promotes extensive CpG island hypermethylation and malignant transformation
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    Longitudinal map of transcriptome changes in the Lyme pathogen Borrelia burgdorferi during tick-borne transmission
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    Histone variants shape chromatin states in Arabidopsis
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    Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming
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    Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation
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    Evolutionary history of Staphylococcus aureus influences antibiotic resistance evolution
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    Bacterial clade-specific analysis identifies distinct epithelial responses in inflammatory bowel disease
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    A clinical metagenomic study of biopsies from Mexican endophthalmitis patients reveals the presence of complex bacterial communities and a diversity of resistance genes
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    Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer
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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome assembly of the hybrid grapevine Vitis ‘Chambourcin’
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    DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres
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  93. 52.53.155.43 52.53.155.43
    Modelling host-Trypanosoma brucei gambiense interactions in vitro using human induced pluripotent stem cell-derived cortical brain organoids
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    (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers
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  95. May 2023
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comparative analysis of microRNA expression profiles in shoot and root tissues of contrasting rice cultivars (Oryza sativa L.) with different salt stress tolerance
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  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developmental dynamics of chromatin accessibility during post-implantation development of monkey embryos
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  99. www.sciencedirect.com www.sciencedirect.com
    Bat ASC2 suppresses inflammasomes and ameliorates inflammatory diseases
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  100. onlinelibrary.wiley.com onlinelibrary.wiley.com
    KMT2D Deficiency Promotes Myeloid Leukemias which Is Vulnerable to Ribosome Biogenesis Inhibition
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    L1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
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  102. Apr 2023
  103. www.sciencedirect.com www.sciencedirect.com
    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
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    Maternal and food microbial sources shape the infant microbiome of a rural Ethiopian population
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    Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
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    Novel enhancers conferring compensatory transcriptional regulation of Nkx2-5 in heart development
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    INTAC endonuclease and phosphatase modules differentially regulate transcription by RNA polymerase II
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    Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload
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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Asparagine starvation suppresses histone demethylation through iron depletion
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    Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting
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  111. Mar 2023
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atria: an ultra-fast and accurate trimmer for adapter and quality trimming
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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome assembly of the roundjaw bonefish (Albula glossodonta), a vulnerable circumtropical sportfish
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    Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion
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    SnakeMAGs: a simple, efficient, flexible and scalable workflow to reconstruct prokaryotic genomes from metagenomes
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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MeCP2 regulates Gdf11, a dosage-sensitive gene critical for neurological function
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    Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eye
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    A chromosome-scale draft genome sequence of horsegram (Macrotyloma uniflorum)
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    Genome assembly of the numbat (Myrmecobius fasciatus), the only termitivorous marsupial
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  120. Feb 2023
  121. www.sciencedirect.com www.sciencedirect.com
    Human hematopoietic stem cell vulnerability to ferroptosis
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    The BRD4 inhibitor JQ1 augments the antitumor efficacy of abemaciclib in preclinical models of gastric carcinoma
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    DDR2 coordinates EMT and metabolic reprogramming as a shared effector of FOXQ1 and SNAI1
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  124. Jan 2023
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    Enrichment of oral-derived bacteria in inflamed colorectal tumors and distinct associations of Fusobacterium in the mesenchymal subtype
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    Genomic view of the diversity and functional role of archaea and bacteria in the skeleton of the reef-building corals Porites lutea and Isopora palifera
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    Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors
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    A chromosome-scale assembly for tetraploid sour cherry (Prunus cerasus L.) ‘Montmorency’ identifies three distinct ancestral Prunus genomes
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    Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers
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    Resistance to white spot syndrome virus in the European shore crab is associated with suppressed virion trafficking and heightened immune responses
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    SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis
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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRC2 Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1 Targeted Therapy via Enhanced Viral Mimicry
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  133. Dec 2022
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    Targeting metabolic adaptations in the breast cancer–liver metastatic niche using dietary approaches to improve endocrine therapy efficacy
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    BAF complex maintains glioma stem cells in pediatric H3K27M-glioma
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  136. Nov 2022
  137. www.sciencedirect.com www.sciencedirect.com
    Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation
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    Transcriptomic Correlates of Tumor Cell PD-L1 Expression and Response to Nivolumab Monotherapy in Metastatic Clear Cell Renal Cell Carcinoma
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    Essential role of MESP1-RING1A complex in cardiac differentiation
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  140. aacrjournals.org aacrjournals.org
    DDR2 Coordinates EMT and Metabolic Reprogramming as a Shared Effector of FOXQ1 and SNAI1
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      DOI: 10.1158/2767-9764.CRC-22-0013

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  141. academic.oup.com academic.oup.com
    High-quality genome assembles from key Hawaiian coral species
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  142. www.sciencedirect.com www.sciencedirect.com
    Transcription factor antagonism regulates heterogeneity in embryonic stem cell states
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  143. Oct 2022
  144. aacrjournals.org aacrjournals.org
    CircIPO7 Promotes Nasopharyngeal Carcinoma Metastasis and Cisplatin Chemoresistance by Facilitating YBX1 Nuclear Localization
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  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA-binding protein Elavl1/HuR is required for maintenance of cranial neural crest specification
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  146. www.sciencedirect.com www.sciencedirect.com
    A cis-regulatory lexicon of DNA motif combinations mediating cell-type-specific gene regulation
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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dicer1 deficient mice exhibit premature ageing and metabolic perturbations in adipocytes
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  148. Sep 2022
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    PU.1-dependent enhancer inhibition separates Tet2-deficient hematopoiesis from malignant transformation
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  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In Vivo Genome-Wide CRISPR Activation Screening Identifies Functionally Important Long Noncoding RNAs in Hepatocellular Carcinoma
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    Genomic analysis reveals cryptic diversity in aphelids and sheds light on the emergence of Fungi
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    Acquired semi-squamatization during chemotherapy suggests differentiation as a therapeutic strategy for bladder cancer
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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of key endosymbiont genes may facilitate early host control of the chromatophore in Paulinella
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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAG2 promotes the myelination transcriptional program in oligodendrocytes
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    The human mitochondrial genome contains a second light strand promoter
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  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intracellular cholesterol pools regulate oncogenic signaling and epigenetic circuitries in Early T-cell Precursor Acute Lymphoblastic Leukemia
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  157. Aug 2022
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    Npas3 deficiency impairs cortical astrogenesis and induces autistic-like behaviors
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  159. 52.53.155.43 52.53.155.43
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  160. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Losartan blocks osteosarcoma-elicited monocyte recruitment, and combined with the kinase inhibitor toceranib, exerts significant clinical benefit in canine metastatic osteosarcoma
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  161. www.sciencedirect.com www.sciencedirect.com
    LncRNA and mRNA expression profiles in brown adipose tissue of obesity-prone and obesity-resistant mice
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  162. www.sciencedirect.com www.sciencedirect.com
    TOP1 CAD-seq: A protocol to map catalytically engaged topoisomerase 1 in human cells
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  163. Jul 2022
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    EGFR signaling activates intestinal stem cells by promoting mitochondrial biogenesis and β-oxidation
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  165. academic.oup.com academic.oup.com
    A chromosome-level genome assembly and intestinal transcriptome of Trypoxylus dichotomus (Coleoptera: Scarabaeidae) to understand its lignocellulose digestion ability
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  166. www.cell.com www.cell.com
    Bacterial growth in multicellular aggregates leads to the emergence of complex life cycles
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  167. Jun 2022
  168. aacrjournals.org aacrjournals.org
    Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors
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  169. aacrjournals.org aacrjournals.org
    Porcupine inhibition disrupts mitochondrial function and homeostasis in WNT ligand-addicted pancreatic cancer
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  170. elifesciences.org elifesciences.org
    Dnmt3a knockout in excitatory neurons impairs postnatal synapse maturation and increases the repressive histone modification H3K27me3
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  171. www.sciencedirect.com www.sciencedirect.com
    Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine
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    JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation
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    Mapping cis-regulatory elements in human neurons links psychiatric disease heritability and activity-regulated transcriptional programs
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    Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion
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  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Whole Transcriptome Analysis in Peripheral Blood Suggests That Energy Metabolism and Inflammation Are Involved in Major Depressive Disorder
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  176. May 2022
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    A chromosome-level reference genome of Ensete glaucum gives insight into diversity and chromosomal and repetitive sequence evolution in the Musaceae
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  178. Apr 2022
  179. www.sciencedirect.com www.sciencedirect.com
    RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex
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    An adult-stage transcriptional program for survival of serotonergic connectivity
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    HNF4A modulates glucocorticoid action in the liver
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  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromosome-level genome of the globe skimmer dragonfly (Pantala flavescens)
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  183. academic.oup.com academic.oup.com
    A high-quality assembled genome and its comparative analysis decode the adaptive molecular mechanism of the number one Chinese cotton variety CRI-12
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  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Presence of H3K4me3 on Paternally Expressed Genes of the Paternal Genome From Sperm to Implantation
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  185. Mar 2022
  186. elifesciences.org elifesciences.org
    Novel insights from a multiomics dissection of the Hayflick limit
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  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit
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  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A test of the pioneer factor hypothesis using ectopic liver gene activation
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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fully resolved assembly of Cryptosporidium parvum
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  191. www.sciencedirect.com www.sciencedirect.com
    Identification of new ETV6 modulators through a high throughput functional screening
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  192. Feb 2022
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    Simultaneous cellular and molecular phenotyping of embryonic mutants using single-cell regulatory trajectories
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    Uncovering the mesendoderm gene regulatory network through multi-omic data integration
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  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic analysis of naturally occurring insertions and deletions that alter transcription factor spacing identifies tolerant and sensitive transcription factor pairs
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  196. Jan 2022
  197. www.sciencedirect.com www.sciencedirect.com
    Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration
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    Multimodal regulatory elements within a hormone-specific super enhancer control a heterogeneous transcriptional response
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    Construction of Strand-seq libraries in open nanoliter arrays
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  200. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells
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  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MAP3K7 loss drives enhanced androgen signaling and independently confers risk of recurrence in prostate cancer with joint loss of CHD1
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  202. Dec 2021
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    Wnt signaling mediates acquisition of blood–brain barrier properties in naïve endothelium derived from human pluripotent stem cells
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  204. www.cell.com www.cell.com
    MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”
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    Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis
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  206. Nov 2021
  207. mcr.aacrjournals.org mcr.aacrjournals.org
    SOX9 Defines Distinct Populations of Cells in SHH Medulloblastoma but Is Not Required for Math1-Driven Tumor Formation
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  208. www.nature.com www.nature.com
    CHD5 inhibits metastasis of neuroblastoma
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    Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1
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    Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis
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    Sequence features of retrotransposons allow for epigenetic variability
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    Kr-h1 maintains distinct caste-specific neurotranscriptomes in response to socially regulated hormones
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  213. Oct 2021
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    Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells
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    Induced intra- and intermolecular template switching as a therapeutic mechanism against RNA viruses
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    Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers
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      DOI: 10.1158/0008-5472.CAN-21-1545

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    Clinical Significance of Circulating Tumor Cell Induced Epithelial-Mesenchymal Transition in Patients with Metastatic Colorectal Cancer by Single-Cell RNA-Sequencing
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  218. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A chromosome-level genome assembly for the eastern fence lizard (Sceloporus undulatus), a reptile model for physiological and evolutionary ecology
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    Acrylamide modulates the mouse epididymal proteome to drive alterations in the sperm small non-coding RNA profile and dysregulate embryo development
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    Global chromatin relabeling accompanies spatial inversion of chromatin in rod photoreceptors
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  221. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tiled-ClickSeq for targeted sequencing of complete coronavirus genomes with simultaneous capture of RNA recombination and minority variants
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  222. Sep 2021
  223. www.science.org www.science.org
    Global chromatin relabeling accompanies spatial inversion of chromatin in rod photoreceptors
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  224. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Monocytic differentiation and AHR signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
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    H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity
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    SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
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    Leveraging the Mendelian disorders of the epigenetic machinery to systematically map functional epigenetic variation
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    Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway
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