361 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    V-pipe 3.0: a sustainable pipeline for within-sample viral genetic diversity estimation
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    1. scibot 02 Oct 2024
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      DOI: 10.1093/gigascience/giae065

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    ncbi.nlm.nih.gov/pmc/articles/PMC11440432/
  3. aacrjournals.org aacrjournals.org
    Monocytic Differentiation and AHR Signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
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    1. scibot 02 Oct 2024
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      DOI: 10.1158/2643-3230.BCD-21-0012

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    aacrjournals.org/bloodcancerdiscov/article/2/5/518/665838/Monocytic-Differentiation-and-AHR-Signaling-as
  4. www.sciencedirect.com www.sciencedirect.com
    Tracing early pastoralism in Central Europe using sedimentary ancient DNA
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    1. scibot 26 Sep 2024
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    sciencedirect.com/science/article/pii/S096098222401162X
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Divergent iron regulatory states contribute to heterogeneity in breast cancer aggressiveness
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    1. scibot 26 Sep 2024
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  6. Sep 2024
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    Multiple direct and indirect roles of the Paf1 complex in transcription elongation, splicing, and histone modifications
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    1. scibot 10 Sep 2024
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    sciencedirect.com/science/article/pii/S2211124724010817
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    Targeting EGLN2/PHD1 protects motor neurons and normalizes the astrocytic interferon response
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    1. scibot 10 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114719

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    sciencedirect.com/science/article/pii/S2211124724010702
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    Streamlined regulation of chloroplast development in the liverwort Marchantia polymorpha
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    1. scibot 06 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114696

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    sciencedirect.com/science/article/pii/S2211124724010477
  10. Aug 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterizing Relationships between T-cell Inflammation and Outcomes in Patients with High-Risk Neuroblastoma According to Mesenchymal and Adrenergic Signatures
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    1. scibot 30 Aug 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11350481/
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    Acral fibrochondromyxoid tumor: a clinicopathologic and molecular genetic study of 37 cases
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    sciencedirect.com/science/article/pii/S0893395224001790
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR screening uncovers a long-range enhancer for ONECUT1 in pancreatic differentiation and links a diabetes risk variant
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    1. scibot 23 Aug 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11406439/
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    Members of an array of zinc-finger proteins specify distinct Hox chromatin boundaries
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    1. scibot 23 Aug 2024
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  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability
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    1. scibot 21 Aug 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11366124/
  16. www.biorxiv.org www.biorxiv.org
    The multi-level effect of chlorpyrifos during clownfish metamorphosis
    1
    1. scibot 20 Aug 2024
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      DOI: 10.1101/2024.08.02.606305

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    biorxiv.org/content/10.1101/2024.08.02.606305v1
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MOBFinder: a tool for mobilization typing of plasmid metagenomic fragments based on a language model
    1
    1. scibot 19 Aug 2024
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      DOI: 10.1093/gigascience/giae047

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    ncbi.nlm.nih.gov/pmc/articles/PMC11299106/
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    A replisome-associated histone H3-H4 chaperone required for epigenetic inheritance
    1
    1. scibot 18 Aug 2024
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      DOI: 10.1016/j.cell.2024.07.006

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  19. www.ncbi.nlm.nih.govhttp www.ncbi.nlm.nih.govhttp
    Heteromeric RNP Assembly at LINEs Controls Lineage-Specific RNA Processing
    1
    1. scibot 02 Aug 2024
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  20. Jul 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
    2
    1. scibot 31 Jul 2024
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      DOI: 10.1158/2159-8290.CD-23-0539

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    ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11275559/
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    Pandemic-associated pernio harbors footprints of an abortive SARS-CoV-2 infection
    1
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    A clinical metagenomic study of biopsies from Mexican endophthalmitis patients reveals the presence of complex bacterial communities and a diversity of resistance genes
    1
    1. scibot 25 Jul 2024
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      DOI: 10.1099/acmi.0.000639.v3

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    Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system
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      DOI: 10.1016/j.immuni.2024.07.001

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    sciencedirect.com/science/article/pii/S1074761324003480
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    MYB-related transcription factors control chloroplast biogenesis
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    1. scibot 24 Jul 2024
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  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A ghost moth olfactory prototype of the lepidopteran sex communication
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      DOI: 10.1093/gigascience/giae044

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  28. www.science.org www.science.org
    The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1
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      DOI: 10.1126/sciadv.adk1296

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  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Netrin signaling mediates survival of dormant epithelial ovarian cancer cells
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      DOI: 10.7554/eLife.91766

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  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma
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  31. www.cell.com www.cell.com
    Maternal gestational diabetes mellitus associates with altered gut microbiome composition and head circumference abnormalities in male offspring
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      DOI: 10.1016/j.chom.2024.06.005

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    cell.com/cell-host-microbe/abstract/S1931-3128(24)00223-3
  32. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004224017255-main-html.html
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    A nuclear architecture screen in Drosophila identifies Stonewall as a link between chromatin position at the nuclear periphery and germline stem cell fate
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      DOI: 10.1101/gad.351424.123

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  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1
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      DOI: 10.1126/sciadv.adk1296

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  35. Jun 2024
  36. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Impacts of in-vitro zebularine treatment on genome-wide DNA methylation and transcriptomic profiles in Salix purpurea L.
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      DOI: 10.1111/ppl.14403

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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A chronic signaling TGFb zebrafish reporter identifies immune response in melanoma
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      DOI: 10.7554/eLife.83527

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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct features of ribonucleotides within genomic DNA in Aicardi-Goutières syndrome ortholog mutants of Saccharomyces cerevisiae
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    Surgical tumour resection deregulates Hallmarks of Cancer in resected tissue and the surrounding microenvironment
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      DOI: 10.1158/1541-7786.MCR-23-0265

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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The telomere-to-telomere (T2T) genome of Peucedanum praeruptorum Dunn provides insights into the genome evolution and coumarin biosynthesis
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      DOI: 10.1093/gigascience/giae025

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  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional response of the heart to vagus nerve stimulation
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      DOI: 10.6084/m9.figshare.24449590

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    ncbi.nlm.nih.gov/pmc/articles/PMC7616044/
  42. molecular-cancer.biomedcentral.com molecular-cancer.biomedcentral.com
    Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients
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      DOI: 10.1186/s12943-024-02034-7

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    molecular-cancer.biomedcentral.com/articles/10.1186/s12943-024-02034-7
  43. May 2024
  44. www.sciencedirect.com www.sciencedirect.com
    Reciprocal conversion between annual and polycarpic perennial flowering behavior in the Brassicaceae
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      DOI: 10.1016/j.cell.2024.04.047

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      DOI: 10.1016/j.cell.2024.04.047

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      DOI: 10.1016/j.cell.2024.04.047

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    sciencedirect.com/science/article/pii/S0092867424004732
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    Heterochromatic 3D genome organization is directed by HP1a- and H3K9-dependent and independent mechanisms
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      DOI: 10.1016/j.molcel.2024.05.002

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    sciencedirect.com/science/article/pii/S1097276524003952
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    Inhibition of HDAC2 sensitises antitumour therapy by promoting NLRP3/GSDMD-mediated pyroptosis in colorectal cancer
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    T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells
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    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
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    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2
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    Development of sexual dimorphism of skeletal muscles through the adrenal cortex, caused by androgen-induced global gene suppression
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    PRDM3/16 Regulate Chromatin Accessibility Required for NKX2-1 Mediated Alveolar Epithelial Differentiation and Function
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    Early microbial intervention reshapes phenotypes of newborn Bos taurus through metabolic regulations
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    Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
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    Pluripotency state transition of embryonic stem cells requires the turnover of histone chaperone FACT on chromatin
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    Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis
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    A single-cell multi-omic atlas spanning the adult rhesus macaque brain
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    Genetic swamping of the critically endangered Scottish wildcat was recent and accelerated by disease
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    Genome organization regulates nuclear pore complex formation and promotes differentiation during Drosophila oogenesis
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    A nuclear architecture screen in Drosophila identifies Stonewall as a link between chromatin position at the nuclear periphery and germline stem cell fate
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  104. Nov 2023
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    Genomic and transcriptomic characterization of delta SARS-CoV-2 infection in free-ranging white-tailed deer (Odocoileus virginianus)
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    Repression of LSD1 potentiates homologous recombination-proficient ovarian cancer to PARP inhibitors through down-regulation of BRCA1/2 and RAD51
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    LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
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    Broodstock nutritional programming differentially affects the hepatic transcriptome and genome-wide DNA methylome of farmed gilthead sea bream (Sparus aurata) depending on genetic background
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    Oral vancomycin treatment suppresses gut trypsin activity and preserves intestinal barrier function during EAE
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    Zinc Finger MYND-Type Containing 8 (ZMYND8) is epigenetically regulated in mutant Isocitrate Dehydrogenase 1 (IDH1) glioma to promote radioresistance
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    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
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    Molecular and functional characterization of the Drosophila melanogaster conserved smORFome
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    Loss of succinyl-CoA synthetase in mouse forebrain results in hypersuccinylation with perturbed neuronal transcription and metabolism
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    Three-dimensional genome architecture coordinates key regulators of lineage specification in mammary epithelial cells
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    A single-cell multi-omic atlas spanning the adult rhesus macaque brain
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    Chromatin accessibility landscape of human triple-negative breast cancer cell lines reveals variation by patient donor ancestry
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    TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression
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    Acquisition of Neural Fate by Combination of BMP Blockade and Chromatin Modification
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    Chromosome-level reference genome of tetraploid Isoetes sinensis provides insights into evolution and adaption of lycophytes
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  126. Sep 2023
  127. 52.53.155.43 52.53.155.43
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    Targeting KDM2A Enhances T Cell Infiltration in NSD1-Deficient Head and Neck Squamous Cell Carcinoma
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  129. Aug 2023
  130. www.biorxiv.org www.biorxiv.org
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3’ UTR of FAIM2
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    Aberrant accumulation of Kras-dependent pervasive transcripts during tumor progression renders cancer cells dependent on PAF1 expression
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  132. 52.53.155.43 52.53.155.43
    SnakeMAGs: a simple, efficient, flexible and scalable workflow to reconstruct prokaryotic genomes from metagenomes
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteasome Inhibition Sensitizes Liposarcoma to MDM2 Inhibition with Nutlin-3 by Activating the ATF4/CHOP Stress Response Pathway
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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficiency of the Polycomb protein RYBP and TET methylcytosine oxidases promotes extensive CpG island hypermethylation and malignant transformation
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    Longitudinal map of transcriptome changes in the Lyme pathogen Borrelia burgdorferi during tick-borne transmission
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    Histone variants shape chromatin states in Arabidopsis
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  137. Jul 2023
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    Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming
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    Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation
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    A clinical metagenomic study of biopsies from Mexican endophthalmitis patients reveals the presence of complex bacterial communities and a diversity of resistance genes
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    Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer
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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome assembly of the hybrid grapevine Vitis ‘Chambourcin’
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  148. Jun 2023
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  151. www.embopress.org www.embopress.org
    DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres
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  152. 52.53.155.43 52.53.155.43
    Modelling host-Trypanosoma brucei gambiense interactions in vitro using human induced pluripotent stem cell-derived cortical brain organoids
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  153. aacrjournals.org aacrjournals.org
    (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers
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  154. May 2023
  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comparative analysis of microRNA expression profiles in shoot and root tissues of contrasting rice cultivars (Oryza sativa L.) with different salt stress tolerance
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  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developmental dynamics of chromatin accessibility during post-implantation development of monkey embryos
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  157. 52.53.155.43 52.53.155.43
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  158. www.sciencedirect.com www.sciencedirect.com
    Bat ASC2 suppresses inflammasomes and ameliorates inflammatory diseases
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  159. onlinelibrary.wiley.com onlinelibrary.wiley.com
    KMT2D Deficiency Promotes Myeloid Leukemias which Is Vulnerable to Ribosome Biogenesis Inhibition
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  161. Apr 2023
  162. www.sciencedirect.com www.sciencedirect.com
    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
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    Maternal and food microbial sources shape the infant microbiome of a rural Ethiopian population
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    Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
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    Novel enhancers conferring compensatory transcriptional regulation of Nkx2-5 in heart development
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    INTAC endonuclease and phosphatase modules differentially regulate transcription by RNA polymerase II
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    Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload
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    Asparagine starvation suppresses histone demethylation through iron depletion
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    Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting
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  170. Mar 2023
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    Atria: an ultra-fast and accurate trimmer for adapter and quality trimming
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    Genome assembly of the roundjaw bonefish (Albula glossodonta), a vulnerable circumtropical sportfish
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    Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion
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    SnakeMAGs: a simple, efficient, flexible and scalable workflow to reconstruct prokaryotic genomes from metagenomes
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  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MeCP2 regulates Gdf11, a dosage-sensitive gene critical for neurological function
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  176. www.cell.com www.cell.com
    Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eye
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  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A chromosome-scale draft genome sequence of horsegram (Macrotyloma uniflorum)
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome assembly of the numbat (Myrmecobius fasciatus), the only termitivorous marsupial
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  179. Feb 2023
  180. www.sciencedirect.com www.sciencedirect.com
    Human hematopoietic stem cell vulnerability to ferroptosis
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  181. link.springer.com link.springer.com
    The BRD4 inhibitor JQ1 augments the antitumor efficacy of abemaciclib in preclinical models of gastric carcinoma
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  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DDR2 coordinates EMT and metabolic reprogramming as a shared effector of FOXQ1 and SNAI1
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  183. Jan 2023
  184. www.sciencedirect.com www.sciencedirect.com
    Enrichment of oral-derived bacteria in inflamed colorectal tumors and distinct associations of Fusobacterium in the mesenchymal subtype
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic view of the diversity and functional role of archaea and bacteria in the skeleton of the reef-building corals Porites lutea and Isopora palifera
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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors
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  187. www.biorxiv.org www.biorxiv.org
    A chromosome-scale assembly for tetraploid sour cherry (Prunus cerasus L.) ‘Montmorency’ identifies three distinct ancestral Prunus genomes
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      DOI: 10.1101/2023.01.10.523438

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  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers
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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Resistance to white spot syndrome virus in the European shore crab is associated with suppressed virion trafficking and heightened immune responses
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis
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  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRC2 Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1 Targeted Therapy via Enhanced Viral Mimicry
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  192. Dec 2022
  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting metabolic adaptations in the breast cancer–liver metastatic niche using dietary approaches to improve endocrine therapy efficacy
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  194. aacrjournals.org aacrjournals.org
    BAF complex maintains glioma stem cells in pediatric H3K27M-glioma
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  195. Nov 2022
  196. www.sciencedirect.com www.sciencedirect.com
    Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation
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  197. aacrjournals.org aacrjournals.org
    Transcriptomic Correlates of Tumor Cell PD-L1 Expression and Response to Nivolumab Monotherapy in Metastatic Clear Cell Renal Cell Carcinoma
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  198. www.sciencedirect.com www.sciencedirect.com
    Essential role of MESP1-RING1A complex in cardiac differentiation
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  199. aacrjournals.org aacrjournals.org
    DDR2 Coordinates EMT and Metabolic Reprogramming as a Shared Effector of FOXQ1 and SNAI1
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  200. academic.oup.com academic.oup.com
    High-quality genome assembles from key Hawaiian coral species
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      DOI: 10.1093/gigascience/giac098

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  201. www.sciencedirect.com www.sciencedirect.com
    Transcription factor antagonism regulates heterogeneity in embryonic stem cell states
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  202. Oct 2022
  203. aacrjournals.org aacrjournals.org
    CircIPO7 Promotes Nasopharyngeal Carcinoma Metastasis and Cisplatin Chemoresistance by Facilitating YBX1 Nuclear Localization
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      DOI: 10.1158/1078-0432.CCR-22-0991

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  204. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA-binding protein Elavl1/HuR is required for maintenance of cranial neural crest specification
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      DOI: 10.7554/eLife.63600

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  205. www.sciencedirect.com www.sciencedirect.com
    A cis-regulatory lexicon of DNA motif combinations mediating cell-type-specific gene regulation
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  206. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dicer1 deficient mice exhibit premature ageing and metabolic perturbations in adipocytes
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  207. Sep 2022
  208. aacrjournals.org aacrjournals.org
    PU.1-dependent enhancer inhibition separates Tet2-deficient hematopoiesis from malignant transformation
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      DOI: 10.1158/2643-3230.BCD-21-0226

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  209. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In Vivo Genome-Wide CRISPR Activation Screening Identifies Functionally Important Long Noncoding RNAs in Hepatocellular Carcinoma
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  210. www.sciencedirect.com www.sciencedirect.com
    Genomic analysis reveals cryptic diversity in aphelids and sheds light on the emergence of Fungi
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    Acquired semi-squamatization during chemotherapy suggests differentiation as a therapeutic strategy for bladder cancer
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  212. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of key endosymbiont genes may facilitate early host control of the chromatophore in Paulinella
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  213. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAG2 promotes the myelination transcriptional program in oligodendrocytes
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      DOI: 10.7554/eLife.77848

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  214. www.sciencedirect.com www.sciencedirect.com
    The human mitochondrial genome contains a second light strand promoter
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  215. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intracellular cholesterol pools regulate oncogenic signaling and epigenetic circuitries in Early T-cell Precursor Acute Lymphoblastic Leukemia
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  216. Aug 2022
  217. www.sciencedirect.com www.sciencedirect.com
    Npas3 deficiency impairs cortical astrogenesis and induces autistic-like behaviors
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  218. 52.53.155.43 52.53.155.43
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  219. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Losartan blocks osteosarcoma-elicited monocyte recruitment, and combined with the kinase inhibitor toceranib, exerts significant clinical benefit in canine metastatic osteosarcoma
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      DOI: 10.1158/1078-0432.CCR-21-2105

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