359 Matching Annotations
  1. Feb 2025
  2. onlinelibrary.wiley.com onlinelibrary.wiley.com
    mTORC2 Regulates Actin Polymerization in Auditory Cells
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70012
  3. www.sciencedirect.com www.sciencedirect.com
    Exploring the characteristics of immortalized human ovarian surface epithelial cell lines
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    sciencedirect.com/science/article/pii/S2405844025009193
  4. www.biorxiv.org www.biorxiv.org
    Network analysis of α-synuclein pathology progression reveals p21-activated kinases as regulators of vulnerability
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    biorxiv.org/content/10.1101/2024.10.22.619411v1
  5. Jan 2025
  6. link.springer.com link.springer.com
    Tofacitinib and budesonide treatment affect stemness and chemokine release in IBD patient-derived colonoids
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    link.springer.com/article/10.1038/s41598-025-86314-2
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    PDE4 inhibitor rolipram represses hedgehog signaling via ubiquitin-mediated proteolysis of GLI transcription factors to regress breast cancer
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    sciencedirect.com/science/article/pii/S0021925825000869
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antibody-based delivery of interleukin-2 modulates the immunosuppressive tumor microenvironment and achieves cure in pancreatic ductal adenocarcinoma syngeneic mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11705946/
  9. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/009f00f9e3d39df3c2a4236499ac454ff01f615a/PDF-html.html
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comparative profiling of white matter development in the human and mouse brain reveals volumetric deficits and delayed myelination in Angelman syndrome
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    pmc.ncbi.nlm.nih.gov/articles/PMC11670556/
  11. Dec 2024
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genomic and transcriptomic landscape of human gastrointestinal stromal tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11532483/
  13. aacrjournals.org aacrjournals.org
    Large-Scale Comparative Analysis of Canine and Human Osteosarcomas Uncovers Conserved Clinically Relevant Tumor Microenvironment Subtypes
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    aacrjournals.org/clincancerres/article/30/24/5630/750426/Large-Scale-Comparative-Analysis-of-Canine-and
  14. www.sciencedirect.com www.sciencedirect.com
    A CNA-35-based high-throughput fibrosis assay reveals ORAI1 as a regulator of collagen release from pancreatic stellate cells
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    sciencedirect.com/science/article/pii/S0945053X2400146X
  15. www.biorxiv.org www.biorxiv.org
    Dissecting the differential role of C-terminal truncations in the regulation of aSyn pathology formation and the biogenesis of Lewy bodies
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    biorxiv.org/content/10.1101/2024.11.29.625993v1
  16. www.science.org www.science.org
    Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer
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    science.org/doi/10.1126/scisignal.adp1375
  17. Nov 2024
  18. 52.53.155.43 52.53.155.43
    cir-24-0324-html.html
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    52.53.155.43/d81834c4f435bac92597aa4fc554551b530ce2ba/cir-24-0324-html.html
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RUNX2 as a novel biomarker for early identification of patients progressing to advanced-stage mycosis fungoides
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    pmc.ncbi.nlm.nih.gov/articles/PMC11491341/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatial transcriptomic analysis of adult hippocampal neurogenesis in the human brain
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    pmc.ncbi.nlm.nih.gov/articles/PMC11495544/
  21. Oct 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CCL28 modulates neutrophil responses during infection with mucosal pathogens
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    ncbi.nlm.nih.gov/pmc/articles/PMC11444682/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxia-Induced Long Noncoding RNA HIF1A-AS2 Regulates Stability of MHC Class I Protein in Head and Neck Cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443317/
  24. www.biorxiv.org www.biorxiv.org
    Combination of Imipridone ONC201 or ONC206 with Temozolomide and Radiotherapy in triple ITR therapy reduces intracranial tumor burden and prolongs survival in an orthotopic wild-type IDH GBM mouse model
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    biorxiv.org/content/10.1101/2024.09.25.610187v1
  25. www.thelancet.com www.thelancet.com
    Profiling steroid hormone landscape of bladder cancer reveals depletion of intratumoural androgens to castration levels: a cross-sectional study
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    thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00395-5/abstract
  26. Sep 2024
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Embryonic origins of forebrain oligodendrocytes revisited by combinatorial genetic fate mapping
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    ncbi.nlm.nih.gov/pmc/articles/PMC11390105/
  28. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Disruption of HSD17B12 in mouse hepatocytes leads to reduced body weight and defect in the lipid droplet expansion associated with microvesicular steatosis
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    faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202400333RR
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intracellular Osteopontin Promotes the Release of TNFα by Mast Cells to Restrain Neuroendocrine Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369624/
  30. Aug 2024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mast Cell Infiltration and Subtype Promote Malignant Transformation of Oral Precancer and Progression of Oral Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11339667/
  32. link.springer.com link.springer.com
    Exploring the relationship between ulcerative colitis, colorectal cancer, and prostate cancer
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    link.springer.com/article/10.1007/s13577-024-01118-2
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Virtual crossmatching reveals upregulation of placental HLA-Class II in chronic histiocytic intervillositis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11319473/
  34. www.sciencedirect.com www.sciencedirect.com
    Multiplex Spatial Omics Reveals Changes in Immune-Epithelial Crosstalk During Inflammation and Dysplasia Development in Chronic IBD Patients
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    sciencedirect.com/science/article/pii/S2589004224017759
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical implications and molecular features of extracellular matrix networks in soft tissue sarcomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292195/
  36. www.frontiersin.org www.frontiersin.org
    Frontiers | Mice, myeloid cells, and dengue: a new model for unraveling vascular leakage mysteries
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    frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2024.1367672/full
  37. Jul 2024
  38. www.cell.com www.cell.com
    Single-cell spatial multiomics reveals tumor microenvironment vulnerabilities in cancer resistance to immunotherapy
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    cell.com/cell-reports/fulltext/S2211-1247(24)00720-4
  39. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Correlation between the number of interstitial neurons of the white matter and number of neurons within cortical layers: Histological analyses in postnatal macaque
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    onlinelibrary.wiley.com/doi/10.1002/cne.25626
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The methyltransferases METTL7A and METTL7B confer resistance to thiol-based histone deacetylase inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11223745/
  41. Jun 2024
  42. www.cell.com www.cell.com
    Teriflunomide/leflunomide synergize with chemotherapeutics by decreasing mitochondrial fragmentation via DRP1 in SCLC
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    cell.com/iscience/abstract/S2589-0042(24)01357-9
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p53 gain-of-function mutation induces metastasis via Brd4-dependent Csf-1 expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10841313/
  44. aacrjournals.org aacrjournals.org
    Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer
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    aacrjournals.org/cancerres/article/84/11/1834/745520/Obesogenic-High-Fat-Diet-and-MYC-Cooperate-to
  45. May 2024
  46. link.springer.com link.springer.com
    A cocktail of rapamycin, acarbose, and phenylbutyrate prevents age-related cognitive decline in mice by targeting multiple aging pathways
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    link.springer.com/article/10.1007/s11357-024-01198-w
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fatal COVID-19 pulmonary disease involves ferroptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11106344/
  48. www.sciencedirect.com www.sciencedirect.com
    Mapping the tumor stress network reveals dynamic shifts in the stromal oxidative stress response
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    sciencedirect.com/science/article/pii/S2211124724005643
  49. www.sciencedirect.com www.sciencedirect.com
    Integrative molecular and spatial analysis reveals evolutionary dynamics and tumor-immune interplay of in situ and invasive acral melanoma
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    sciencedirect.com/science/article/pii/S1535610824001363
  50. www.sciencedirect.com www.sciencedirect.com
    The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation
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    sciencedirect.com/science/article/pii/S1074761324002218
  51. Apr 2024
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-invasive PET imaging of liver fibrogenesis using a RESCA-conjugated Affibody molecule
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    ncbi.nlm.nih.gov/pmc/articles/PMC11039342/
  53. www.sciencedirect.com www.sciencedirect.com
    Identification of hypoxic macrophages in glioblastoma with therapeutic potential for vasculature normalization
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    sciencedirect.com/science/article/pii/S1535610824001193
  54. aacrjournals.org aacrjournals.org
    Adipose triglyceride lipase is a therapeutic target in advanced prostate cancer that promotes metabolic plasticity
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    aacrjournals.org/cancerres/article/84/5/703/734936/Adipose-Triglyceride-Lipase-Is-a-Therapeutic
  55. aacrjournals.org aacrjournals.org
    Mesothelin Secretion by Pancreatic Cancer Cells Co-opts Macrophages and Promotes Metastasis
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    aacrjournals.org/cancerres/article/84/4/527/734130/Mesothelin-Secretion-by-Pancreatic-Cancer-Cells-Co
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A multivalent peptoid conjugate modulates androgen receptor transcriptional activity to inhibit therapy-resistant prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10592247/
  57. Mar 2024
  58. www.sciencedirect.com www.sciencedirect.com
    Real-time glioblastoma tumor microenvironment assessment by SpiderMass for improved patient management
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    sciencedirect.com/science/article/pii/S2666379124001289
  59. www.nature.com www.nature.com
    Spatial transcriptomics reveals molecular dysfunction associated with cortical Lewy pathology
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    nature.com/articles/s41467-024-47027-8
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10959657/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A topographical atlas of α-synuclein dosage and cell type-specific expression in adult mouse brain and peripheral organs
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    ncbi.nlm.nih.gov/pmc/articles/PMC10951202/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10910783/
  63. Feb 2024
  64. www.sciencedirect.com www.sciencedirect.com
    Single-nucleus RNA sequencing demonstrates an autosomal dominant Alzheimer’s disease profile and possible mechanisms of disease protection
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    sciencedirect.com/science/article/pii/S089662732400093X
  65. aacrjournals.org aacrjournals.org
    FASN Gene Methylation is Associated with Fatty Acid Synthase Expression and Clinical-Genomic Features of Prostate Cancer
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    aacrjournals.org/cancerrescommun/article/4/1/152/733383/FASN-Gene-Methylation-is-Associated-with-Fatty
  66. 52.53.155.43 52.53.155.43
    can-23-0555-html.html
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach
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    ncbi.nlm.nih.gov/pmc/articles/PMC10870121/
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exhausted tumor-infiltrating CD39+CD103+ CD8+ T cells unveil potential for increased survival in human pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10875982/
  69. www.biorxiv.org www.biorxiv.org
    PTPRZ1-targeting RNA CAR-T cells exert antigen-specific and bystander antitumor activity in glioblastoma
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    biorxiv.org/content/10.1101/2023.12.23.573190v1
  70. Jan 2024
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lethal severe fever with thrombocytopenia syndrome virus infection causes systemic germinal centre failure and massive T cell apoptosis in cats
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    ncbi.nlm.nih.gov/pmc/articles/PMC10796997/
  72. aacrjournals.org aacrjournals.org
    FASN Gene Methylation is Associated with Fatty Acid Synthase Expression and Clinical-Genomic Features of Prostate Cancer
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    aacrjournals.org/cancerrescommun/article/4/1/152/733383/FASN-Gene-Methylation-is-Associated-with-Fatty
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucose Deprivation Promotes Pseudohypoxia and Dedifferentiation in Lung Adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10790128/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential Regulation of the Stimulator of Interferon Genes pathway in Human Papillomavirus positive and negative Head and Neck Cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10793589/
  75. www.sciencedirect.com www.sciencedirect.com
    Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk
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    sciencedirect.com/science/article/pii/S1934590923004320
  76. Dec 2023
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality
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    ncbi.nlm.nih.gov/pmc/articles/PMC10722143/
  78. www.sciencedirect.com www.sciencedirect.com
    Central glucagon-like peptide 1 receptor activation inhibits Toll-like receptor agonist-induced inflammation
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    sciencedirect.com/science/article/pii/S1550413123004205
  79. link.springer.com link.springer.com
    Development and validation of an expanded antibody toolset that captures alpha-synuclein pathological diversity in Lewy body diseases
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    link.springer.com/article/10.1038/s41531-023-00604-y
  80. Nov 2023
  81. www.nature.com www.nature.com
    Selective inhibition of CDK9 in triple negative breast cancer
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    nature.com/articles/s41388-023-02892-3
  82. www.sciencedirect.com www.sciencedirect.com
    A role for the subthalamic nucleus in aversive learning
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    sciencedirect.com/science/article/pii/S2211124723013402
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combination Therapies to Improve the Efficacy of Immunotherapy in Triple-negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10618734/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acid-base homeostasis orchestrated by NHE1 defines the pancreatic stellate cell phenotype in pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10619433/
  85. www.sciencedirect.com www.sciencedirect.com
    IL-4 shapes microglia-dependent pruning of the cerebellum during postnatal development
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    sciencedirect.com/science/article/pii/S0896627323007183
  86. www.sciencedirect.com www.sciencedirect.com
    Insulin receptor loss impairs mammary tumorigenesis in mice
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    sciencedirect.com/science/article/pii/S2211124723012639
  87. Oct 2023
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immunotherapy with STING and TLR9 agonists promotes synergistic therapeutic efficacy with suppressed cancer-associated fibroblasts in colon carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10611477/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biomimetic superabsorbent hydrogel acts as a gut protective dynamic exoskeleton improving metabolic parameters and expanding A. muciniphila
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    ncbi.nlm.nih.gov/pmc/articles/PMC10591066/
  90. Sep 2023
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    mTORC2 regulates auditory hair cell structure and function
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    ncbi.nlm.nih.gov/pmc/articles/PMC10484995/
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10482429/
  93. Aug 2023
  94. www.sciencedirect.com www.sciencedirect.com
    Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia
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    sciencedirect.com/science/article/pii/S2211124723009932
  95. www.sciencedirect.com www.sciencedirect.com
    Role of NaV1.6-mediated persistent sodium current and bursting-pacemaker properties in breathing rhythm generation
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    sciencedirect.com/science/article/pii/S2211124723010112
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spermatogonial fate in mice with increased activin A bioactivity and testicular somatic cell tumours
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    ncbi.nlm.nih.gov/pmc/articles/PMC10409995/
  97. www.sciencedirect.com www.sciencedirect.com
    Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer
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    sciencedirect.com/science/article/pii/S1535610823002453
  98. www.sciencedirect.com www.sciencedirect.com
    DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
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    sciencedirect.com/science/article/pii/S2211124723009385
  99. Jul 2023
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mating-induced prolactin surge is not required for subsequent neurogenesis in male mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10356981/
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GSK-3 Inhibitor Elraglusib Enhances Tumor-Infiltrating Immune Cell Activation in Tumor Biopsies and Synergizes with Anti-PD-L1 in a Murine Model of Colorectal Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10342141/
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Target cell-specific synaptic dynamics of excitatory to inhibitory neuron connections in supragranular layers of human neocortex
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    ncbi.nlm.nih.gov/pmc/articles/PMC10332811/
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Compendium of Syngeneic, Transplantable Pediatric High-Grade Glioma Models Reveals Subtype-Specific Therapeutic Vulnerabilities
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  104. Jun 2023
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  117. Apr 2023
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  121. Mar 2023
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  125. Feb 2023
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  130. Jan 2023
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  133. Dec 2022
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  139. Nov 2022
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  144. Oct 2022
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  149. Aug 2022
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  154. Apr 2022
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  160. Mar 2022
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  165. Dec 2021
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  169. Nov 2021
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  171. Oct 2021
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  174. Sep 2021
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  177. Jul 2021
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  180. May 2021
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    Specific populations of basal ganglia output neurons target distinct brain stem areas while collateralizing throughout the diencephalon
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  185. Apr 2021
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    Mitochondria Define Intestinal Stem Cell Differentiation Downstream of a FOXO/Notch Axis
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  187. Mar 2021
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  190. Feb 2021
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    RUNX1 marks a luminal castration-resistant lineage established at the onset of prostate development
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  193. Nov 2020
  194. www.cell.com www.cell.com
    Persistent Activity of Metabotropic Glutamate Receptor 5 in the Periaqueductal Gray Constrains Emergence of Chronic Neuropathic Pain
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  195. Sep 2020
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    Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth
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