220 Matching Annotations
  1. Aug 2025
  2. www.sciencedirect.com www.sciencedirect.com
    Unfolded protein response transcription factor XBP1 suppresses necroptosis-induced colitis by reinforcing the mucus barrier
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    sciencedirect.com/science/article/pii/S1074761325003322
  3. 52.53.155.43 52.53.155.43
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    52.53.155.43/4f5d98badff0b027bead3e4817e6ce51eaa45443/1-s2.0-S2589004225015718-main-html.html
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations
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    pmc.ncbi.nlm.nih.gov/articles/PMC12319405/
  5. www.biorxiv.org www.biorxiv.org
    Using CCDC6 immunostaining in conjunction with the RAD51 HRD assay as a novel approach to expand PARPi treatment eligibility in HGSOC patients
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    biorxiv.org/content/10.1101/2025.07.29.667411v1
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel insights into post-myocardial infarction cardiac remodeling through algorithmic detection of cell-type composition shifts
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    pmc.ncbi.nlm.nih.gov/articles/PMC12309993/
  7. Jul 2025
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    Gut substrate trap of D-lactate from microbiota improves blood glucose and fatty liver disease in obese mice
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    sciencedirect.com/science/article/pii/S1550413125003286
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Distribution and morphological features of astrocytes and Purkinje cells in the human cerebellum
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    pmc.ncbi.nlm.nih.gov/articles/PMC12271190/
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    β-catenin functions as a molecular adapter for disordered cBAF interactions
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    sciencedirect.com/science/article/pii/S1097276525005763
  11. www.cell.com www.cell.com
    SLC7A11 protects amoeboid-disseminating cancer cells from oxidative stress
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    cell.com/cell-reports/fulltext/S2211-1247(25)00710-7
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuro-mesenchymal interaction mediated by a β2 adrenergic-nerve growth factor feedforward loop promotes colorectal cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11729495/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Early adipose tissue wasting in a novel preclinical model of human lung cancer cachexia
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    pmc.ncbi.nlm.nih.gov/articles/PMC11623500/
  14. academic.oup.com academic.oup.com
    LAG3-MHCII interaction induces a tight cell-cell interface at the immunological synapse
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    academic.oup.com/jimmunol/advance-article/doi/10.1093/jimmun/vkaf120/8175755
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Excessive firing of dyskinesia-associated striatal direct pathway neurons is gated by dopamine and excitatory synaptic input
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    pmc.ncbi.nlm.nih.gov/articles/PMC12080562/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Methodology for generating chorioallantoic membrane patient-derived xenograft (CAM-PDX) models of pleural mesothelioma and performing preclinical imaging for the translation of cancer studies and drug screening
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    pmc.ncbi.nlm.nih.gov/articles/PMC12188182/
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    Mutant p53 exploits enhancers to elevate immunosuppressive chemokine expression and impair immune checkpoint inhibitors in pancreatic cancer
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    sciencedirect.com/science/article/pii/S1074761325002742
  18. Jun 2025
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    A CXCR4 partial agonist improves immunotherapy by targeting immunosuppressive neutrophils and cancer-driven granulopoiesis
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    sciencedirect.com/science/article/pii/S1535610825002569
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    ABBA+BraiAn, an integrated suite for whole-brain mapping, reveals brain-wide differences in immediate-early genes induction upon learning
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    sciencedirect.com/science/article/pii/S2211124725006473
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multimarker Assessment of B-Cell and Plasma Cell Subsets and Their Prognostic Role in the Colorectal Cancer Microenvironment
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    pmc.ncbi.nlm.nih.gov/articles/PMC12163598/
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    Protective Properties of the White Button Mushroom, Agaricus bisporus, in a Mouse Model of Colitis
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    onlinelibrary.wiley.com/doi/10.1002/mnfr.70133
  23. 52.53.155.43 52.53.155.43
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  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual Role of NRF2 in Pancreatic Precursor Lesions
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    pmc.ncbi.nlm.nih.gov/articles/PMC12158068/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Aged and BRCA-Mutated Stromal Cells Drive Epithelial Cell Transformation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12130807/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Oncogenic H-RAS induces metformin resistance in head and neck cancer by promoting glycolytic metabolism
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    pmc.ncbi.nlm.nih.gov/articles/PMC11969736/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FOXM1 cooperates with ERα to regulate functional β-cell mass
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    pmc.ncbi.nlm.nih.gov/articles/PMC12145799/
  28. elifesciences.org elifesciences.org
    Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular disease
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    elifesciences.org/reviewed-preprints/98558v2
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SETD2 suppresses tumorigenesis in a KRASG12C-driven lung cancer model and its catalytic activity is regulated by histone acetylation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12132414/
  30. May 2025
  31. link.springer.com link.springer.com
    Tumour-associated macrophage infiltration differs in meningioma genotypes, and is important in tumour dynamics
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    link.springer.com/article/10.1186/s13046-025-03419-2
  32. 52.53.155.43 52.53.155.43
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    Hippo signaling is essential for the maintenance of zona glomerulosa cell fate in the murine adrenal cortex
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    pmc.ncbi.nlm.nih.gov/articles/PMC12041920/
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  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Memory T‐Cell Phenotype in Cutaneous T‐Cell Lymphoma Is Modified by Germline Gene Gametocyte Specific Factor 1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12078864/
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  37. www.sciencedirect.com www.sciencedirect.com
    MMRNet: Ensemble deep learning models for predicting mismatch repair deficiency in endometrial cancer from histopathological images
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    sciencedirect.com/science/article/pii/S2666379125001727
  38. elifesciences.org elifesciences.org
    Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular disease
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    elifesciences.org/articles/98558
  39. Apr 2025
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular elucidation of brain lipofuscin in aging and Neuronal Ceroid Lipofuscinosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11957193/
  41. www.jneurosci.org www.jneurosci.org
    Coronin1A regulates the trafficking of alpha synuclein in microglia
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    jneurosci.org/content/45/11/e1337242025
  42. www.nature.com www.nature.com
    Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease
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    nature.com/articles/s41593-024-01791-4
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Early Neutrophil Activation in Psoriatic Skin at Relapse Following Dead Sea Climatotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11969059/
  44. www.sciencedirect.com www.sciencedirect.com
    Histamine 1 Receptor (HRH1): A potential therapeutic target for Pancreatic Ductal Adenocarcinoma
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    sciencedirect.com/science/article/pii/S0022356525397867
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LNS8801: An Enantiomerically Pure Agonist of the G Protein–Coupled Estrogen Receptor Suitable for Clinical Development
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    pmc.ncbi.nlm.nih.gov/articles/PMC11969138/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Trabectedin Enhances the Antitumor Effects of IL-12 in Triple-Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962391/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combination of Bremachlorin PDT and Immune Checkpoint Inhibitor Anti–PD-1 Shows Response in Murine Immunological T-cell–High and T-cell–Low PDAC Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962392/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Phase I Clinical Trial of Intrahepatic Artery Delivery of TG6002 in Combination with Oral 5-Fluorocytosine in Patients with Liver-Dominant Metastatic Colorectal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11959272/
  49. Mar 2025
  50. www.sciencedirect.com www.sciencedirect.com
    Lineage contribution of the mesendoderm progenitors in the gastrulating mouse embryo
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    sciencedirect.com/science/article/pii/S1534580725001200
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Regional analysis of myelin basic protein across postnatal brain development of C57BL/6J mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11922784/
  52. 52.53.155.43 52.53.155.43
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    Targeting WEE1 kinase as a therapeutic strategy in ATIP3-deficient breast cancers
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    sciencedirect.com/science/article/pii/S0304383525002319
  55. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13820
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Eco-evolutionary Guided Pathomics Analysis to Predict DCIS Upstaging
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    pmc.ncbi.nlm.nih.gov/articles/PMC11230267/
  57. www.sciencedirect.com www.sciencedirect.com
    Growth of the maternal intestine during reproduction
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    sciencedirect.com/science/article/pii/S0092867425002004
  58. www.sciencedirect.com www.sciencedirect.com
    Keloid vasculature reacts to intralesional injection therapies but does not predict the response to treatment: Biopsies from double-blinded, randomized, controlled trial
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    sciencedirect.com/science/article/pii/S0925443925001358
  59. www.biorxiv.org www.biorxiv.org
    Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency
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    biorxiv.org/content/10.1101/2025.03.07.642026v1
  60. www.sciencedirect.com www.sciencedirect.com
    Effective targeting of PDGFRA-altered high-grade glioma with avapritinib
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    sciencedirect.com/science/article/pii/S1535610825000704
  61. Feb 2025
  62. www.sciencedirect.com www.sciencedirect.com
    The kinase RIPK3 promotes neuronal survival by suppressing excitatory neurotransmission during central nervous system viral infection
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    sciencedirect.com/science/article/pii/S1074761325000664
  63. www.sciencedirect.com www.sciencedirect.com
    A posterior insula to lateral amygdala pathway transmits US-offset information with a limited role in fear learning
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    sciencedirect.com/science/article/pii/S2211124725000919
  64. aacrjournals.org aacrjournals.org
    Targeting GPC2 on intraocular and CNS metastatic retinoblastomas with local and systemic delivery of CAR T-cells
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    aacrjournals.org/clincancerres/article/30/16/3578/746772/Targeting-GPC2-on-Intraocular-and-CNS-Metastatic
  65. aacrjournals.org aacrjournals.org
    GDF-15 predicts epithelioid hemangioendothelioma aggressiveness and is down-regulated by sirolimus through ATF4/ATF5 suppression
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    aacrjournals.org/clincancerres/article/30/22/5122/749578/GDF-15-Predicts-Epithelioid-Hemangioendothelioma
  66. aacrjournals.org aacrjournals.org
    Streamlined Intraoperative Brain Tumor Classification and Molecular Subtyping in Stereotactic Biopsies Using Stimulated Raman Histology and Deep Learning
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    aacrjournals.org/clincancerres/article/30/17/3824/747281/Streamlined-Intraoperative-Brain-Tumor
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pilot clinical trial of neoadjuvant toll-like receptor 7 agonist (Imiquimod) immunotherapy in early-stage oral squamous cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11807971/
  68. onlinelibrary.wiley.com onlinelibrary.wiley.com
    mTORC2 Regulates Actin Polymerization in Auditory Cells
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70012
  69. www.sciencedirect.com www.sciencedirect.com
    Exploring the characteristics of immortalized human ovarian surface epithelial cell lines
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    sciencedirect.com/science/article/pii/S2405844025009193
  70. www.biorxiv.org www.biorxiv.org
    Network analysis of α-synuclein pathology progression reveals p21-activated kinases as regulators of vulnerability
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    biorxiv.org/content/10.1101/2024.10.22.619411v1
  71. Jan 2025
  72. link.springer.com link.springer.com
    Tofacitinib and budesonide treatment affect stemness and chemokine release in IBD patient-derived colonoids
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    link.springer.com/article/10.1038/s41598-025-86314-2
  73. www.sciencedirect.com www.sciencedirect.com
    PDE4 inhibitor rolipram represses hedgehog signaling via ubiquitin-mediated proteolysis of GLI transcription factors to regress breast cancer
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    sciencedirect.com/science/article/pii/S0021925825000869
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antibody-based delivery of interleukin-2 modulates the immunosuppressive tumor microenvironment and achieves cure in pancreatic ductal adenocarcinoma syngeneic mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11705946/
  75. 52.53.155.43 52.53.155.43
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    Comparative profiling of white matter development in the human and mouse brain reveals volumetric deficits and delayed myelination in Angelman syndrome
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    pmc.ncbi.nlm.nih.gov/articles/PMC11670556/
  77. Dec 2024
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genomic and transcriptomic landscape of human gastrointestinal stromal tumors
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  79. aacrjournals.org aacrjournals.org
    Large-Scale Comparative Analysis of Canine and Human Osteosarcomas Uncovers Conserved Clinically Relevant Tumor Microenvironment Subtypes
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    aacrjournals.org/clincancerres/article/30/24/5630/750426/Large-Scale-Comparative-Analysis-of-Canine-and
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    A CNA-35-based high-throughput fibrosis assay reveals ORAI1 as a regulator of collagen release from pancreatic stellate cells
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  81. www.biorxiv.org www.biorxiv.org
    Dissecting the differential role of C-terminal truncations in the regulation of aSyn pathology formation and the biogenesis of Lewy bodies
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    biorxiv.org/content/10.1101/2024.11.29.625993v1
  82. www.science.org www.science.org
    Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer
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    science.org/doi/10.1126/scisignal.adp1375
  83. Nov 2024
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    RUNX2 as a novel biomarker for early identification of patients progressing to advanced-stage mycosis fungoides
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  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatial transcriptomic analysis of adult hippocampal neurogenesis in the human brain
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    pmc.ncbi.nlm.nih.gov/articles/PMC11495544/
  87. Oct 2024
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CCL28 modulates neutrophil responses during infection with mucosal pathogens
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxia-Induced Long Noncoding RNA HIF1A-AS2 Regulates Stability of MHC Class I Protein in Head and Neck Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443317/
  90. www.biorxiv.org www.biorxiv.org
    Combination of Imipridone ONC201 or ONC206 with Temozolomide and Radiotherapy in triple ITR therapy reduces intracranial tumor burden and prolongs survival in an orthotopic wild-type IDH GBM mouse model
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    biorxiv.org/content/10.1101/2024.09.25.610187v1
  91. www.thelancet.com www.thelancet.com
    Profiling steroid hormone landscape of bladder cancer reveals depletion of intratumoural androgens to castration levels: a cross-sectional study
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    thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00395-5/abstract
  92. Sep 2024
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Embryonic origins of forebrain oligodendrocytes revisited by combinatorial genetic fate mapping
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    ncbi.nlm.nih.gov/pmc/articles/PMC11390105/
  94. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Disruption of HSD17B12 in mouse hepatocytes leads to reduced body weight and defect in the lipid droplet expansion associated with microvesicular steatosis
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    faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202400333RR
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intracellular Osteopontin Promotes the Release of TNFα by Mast Cells to Restrain Neuroendocrine Prostate Cancer
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    IL-1β expression driven by androgen receptor absence or inactivation promotes prostate cancer bone metastasis
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  201. aacrjournals.org aacrjournals.org
    IL-1β expression driven by androgen receptor absence or inactivation promotes prostate cancer bone metastasis
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    Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer’s disease and primary tauopathies
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  203. www.sciencedirect.com www.sciencedirect.com
    B cell expansion hinders the stroma-epithelium regenerative cross talk during mucosal healing
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  204. aacrjournals.org aacrjournals.org
    BAF complex maintains glioma stem cells in pediatric H3K27M-glioma
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    aacrjournals.org/cancerdiscovery/article/12/12/2880/711164/BAF-Complex-Maintains-Glioma-Stem-Cells-in
  205. Nov 2022
  206. aacrjournals.org aacrjournals.org
    Lipid metabolic reprogramming extends beyond histological tumor demarcations in operable human pancreatic cancer
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    aacrjournals.org/cancerres/article/82/21/3932/709964/Lipid-Metabolic-Reprogramming-Extends-beyond
  207. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex
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  208. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glutathione in the nucleus accumbens regulates motivation to exert reward-incentivized effort
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  209. www.sciencedirect.com www.sciencedirect.com
    Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia
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  210. Oct 2022
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    Neurodevelopmental patterns of early postnatal white matter maturation represent distinct underlying microstructure and histology
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  213. Sep 2022
  214. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defining the Immune Checkpoint Landscape in Human Colorectal Cancer Highlights the Relevance of the TIGIT/CD155 Axis for Optimizing Immunotherapy
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  215. Aug 2022
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    Divergent roles for the gut intraepithelial lymphocyte GLP-1R in control of metabolism, microbiota, and T cell-induced inflammation
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    Rapid GPR183-mediated recruitment of eosinophils to the lung after Mycobacterium tuberculosis infection
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  218. Jun 2022
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    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
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  220. Apr 2022
  221. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteomic-Based Machine Learning Analysis Reveals PYGB as a Novel Immunohistochemical Biomarker to Distinguish Inverted Urothelial Papilloma From Low-Grade Papillary Urothelial Carcinoma With Inverted Growth
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    Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease
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  223. aacrjournals.org aacrjournals.org
    Acquired resistance to EZH2 inhibitor GSK343 promotes the differentiation of human DLBCL cell lines towards an ABC-like phenotype
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    FREQUENCY AND GENOMIC ASPECTS OF INTRINSIC RESISTANCE TO VISMODEGIB IN LOCALLY ADVANCED BASAL CELL CARCINOMA
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    Cancer cells retrace a stepwise differentiation program during malignant progression
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  226. Mar 2022
  227. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Climatotherapy at the Dead Sea for psoriasis is a highly effective anti-inflammatory treatment in the short term: An immunohistochemical study
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  228. Feb 2022
  229. www.sciencedirect.com www.sciencedirect.com
    Immune translational control by CPEB4 regulates intestinal inflammation resolution and colorectal cancer development
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  230. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Maternal diet-induced obesity during pregnancy alters lipid supply to mouse E18.5 fetuses and changes the cardiac tissue lipidome in a sex-dependent manner
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  231. Dec 2021
  232. elifesciences.org elifesciences.org
    Coronary blood vessels from distinct origins converge to equivalent states during mouse and human development
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    elifesciences.org/articles/70246