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Sep 2020
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Ribosome Recycling by ABCE1 Links Lysosomal Function and Iron Homeostasis to 3ʹ UTR-Directed Regulation and Nonsense-Mediated Decay

1
1. scibot 15 Sep 2020
  
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  Addgene_12260
  
  DOI: 10.1016/j.celrep.2020.107895
  
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sciencedirect.com/science/article/pii/S2211124720308767
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A universal reporter cell line for bioactivity evaluation of engineered cytokine products

1
1. scibot 15 Sep 2020
  
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  RRID:Addgene_12260
  
  DOI: 10.1038/s41598-020-60182-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7040017/
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A FAK/HDAC5 signaling axis controls osteocyte mechanotransduction

1
1. scibot 14 Sep 2020
  
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  plasmid_12260
  
  DOI: 10.1038/s41467-020-17099-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7329900/
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SIX2 Regulates Human β Cell Differentiation from Stem Cells and Functional Maturation In Vitro

1
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.celrep.2020.107687
  
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sciencedirect.com/science/article/pii/S2211124720306409
onlinelibrary.wiley.com onlinelibrary.wiley.com

Inhibition of the catalytic subunit of DNA‐dependent protein kinase (DNA‐PKcs) stimulates osteoblastogenesis by potentiating bone morphogenetic protein 2 (BMP2) responses

1
1. scibot 13 Sep 2020
  
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  RRID:Addgene_12260
  
  DOI: 10.1002/jcp.29927
  
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onlinelibrary.wiley.com/doi/10.1002/jcp.29927
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Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia

1
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  RRID:Addgene_12260
  
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sciencedirect.com/science/article/pii/S2211124720307609
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Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis

1
1. scibot 13 Sep 2020
  
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.cmet.2020.04.011
  
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sciencedirect.com/science/article/pii/S1550413120301935
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Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells

1
1. scibot 13 Sep 2020
  
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.celrep.2020.03.029
  
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sciencedirect.com/science/article/pii/S2211124720303430
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Targeted Degradation of SLC Transporters Reveals Amenability of Multi-Pass Transmembrane Proteins to Ligand-Induced Proteolysis

2
1. scibot 12 Sep 2020
  
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  Addgene_12260
  
  DOI: 10.1016/j.chembiol.2020.04.003
  
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2. scibot 03 Sep 2020
  
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  Addgene #12260
  
  DOI: 10.1016/j.chembiol.2020.04.003
  
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sciencedirect.com/science/article/pii/S2451945620301173
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Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma

2
1. scibot 11 Sep 2020
  
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.ccell.2020.04.002
  
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2. scibot 04 Sep 2020
  
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  RRID: Addgene_12260
  
  DOI: 10.1016/j.ccell.2020.04.002
  
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sciencedirect.com/science/article/pii/S1535610820301641
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Locally acting transcription factors regulate p53-dependent cis-regulatory element activity

1
1. scibot 11 Sep 2020
  
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  RRID:Addgene_12260
  
  DOI: 10.1093/nar/gkaa147
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7192610/
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A CRISPR knockout negative screen reveals synergy between CDKs inhibitor and metformin in the treatment of human cancer in vitro and in vivo

1
1. scibot 11 Sep 2020
  
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  RRID:Addgene_12260
  
  DOI: 10.1038/s41392-020-0203-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7434905/
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Splicing variation of BMP2K balances abundance of COPII assemblies and autophagic degradation in erythroid cells

1
1. scibot 11 Sep 2020
  
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  plasmid_12260
  
  DOI: 10.7554/eLife.58504
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7473771/
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YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways

1
1. scibot 10 Sep 2020
  
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  psPAX2
  
  DOI: 10.1016/j.celrep.2020.108120
  
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  RRID:Addgene_12260 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124720311098
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Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis

1
1. scibot 10 Sep 2020
  
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.stem.2019.11.016
  
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sciencedirect.com/science/article/pii/S1934590919304710
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An Optimized Protocol for Human Direct Cardiac Reprogramming

1
1. scibot 10 Sep 2020
  
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.xpro.2019.100010
  
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sciencedirect.com/science/article/pii/S2666166719300103
link.springer.com link.springer.com

A Modified Lentivirus-Based Reporter for Magnetic Separation of Cancer Stem Cells

1
1. scibot 10 Sep 2020
  
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  RRID:Addgene_12260
  
  DOI: 10.1134/S0026893319040046
  
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link.springer.com/article/10.1134/S0026893319040046
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A pooled genome-wide screening strategy to identify and rank influenza host restriction factors in cell-based vaccine production platforms

1
1. scibot 10 Sep 2020
  
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  Addgene_12260
  
  DOI: 10.1038/s41598-020-68934-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7376217/
journals.plos.org journals.plos.org

Primate lentiviruses require Inositol hexakisphosphate (IP6) or inositol pentakisphosphate (IP5) for the production of viral particles

1
1. scibot 09 Sep 2020
  
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  RRID:Addgene_12260
  
  DOI: 10.1371/journal.ppat.1008646
  
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journals.plos.org/plospathogens/article
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Absolute Quantification of Transcription Factors Reveals Principles of Gene Regulation in Erythropoiesis

1
1. scibot 09 Sep 2020
  
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.molcel.2020.03.031
  
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sciencedirect.com/science/article/pii/S1097276520301994
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Super-Enhancer Redistribution as a Mechanism of Broad Gene Dysregulation in Repeatedly Drug-Treated Cancer Cells

1
1. scibot 09 Sep 2020
  
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.celrep.2020.107532
  
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sciencedirect.com/science/article/pii/S2211124720304320
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

The oncofetal RNA-binding protein IGF2BP1 is a druggable, post-transcriptional super-enhancer of E2F-driven gene expression in cancer

1
1. scibot 09 Sep 2020
  
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  Plasmid_12260
  
  DOI: 10.1093/nar/gkaa653
  
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pubmed.ncbi.nlm.nih.gov/32761127/
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Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria

1
1. scibot 09 Sep 2020
  
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  RRID:Addgene_12260
  
  DOI: 10.7554/eLife.58041
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7470841/
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model

1
1. scibot 08 Sep 2020
  
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.devcel.2020.06.039
  
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pubmed.ncbi.nlm.nih.gov/32710848/
bioone.org bioone.org

Endogenous Retrovirus Activation as a Key Mechanism of Anti-Tumor Immune Response in Radiotherapy

1
1. scibot 07 Sep 2020
  
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  RRID:Addgene_12260
  
  DOI: 10.1667/RADE-20-00013
  
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bioone.org/journals/radiation-research/volume-193/issue-4/RADE-20-00013/Endogenous-Retrovirus-Activation-as-a-Key-Mechanism-of-Anti-Tumor/10.1667/RADE-20-00013.full
elifesciences.org elifesciences.org

Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model

1
1. scibot 07 Sep 2020
  
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  RRID:Addgene_12260
  
  DOI: 10.7554/eLife.52069
  
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elifesciences.org/articles/52069
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JNK signalling regulates antioxidant responses in neurons

1
1. scibot 06 Sep 2020
  
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.redox.2020.101712
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7502373/
academic.oup.com academic.oup.com

Knockout of USP19 Deubiquitinating Enzyme Prevents Muscle Wasting by Modulating Insulin and Glucocorticoid Signaling

1
1. scibot 04 Sep 2020
  
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  psPAX2
  
  DOI: 10.1210/en.2018-00290
  
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  Curator: @Naa003
  
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academic.oup.com/endo/article/159/8/2966/5035244
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RSK2 Maintains Adult Estrogen Homeostasis by Inhibiting ERK1/2-Mediated Degradation of Estrogen Receptor Alpha

1
1. scibot 04 Sep 2020
  
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  Addgene Cat #12260
  
  DOI: 10.1016/j.celrep.2020.107931
  
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sciencedirect.com/science/article/pii/S2211124720309128
www.jbc.org www.jbc.org

Long noncoding RNA pncRNA-D reduces cyclin D1 gene expression and arrests cell cycle through RNA m6A modification

1
1. scibot 04 Sep 2020
  
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  psPAX2
  
  DOI: 10.1074/jbc.RA119.011556
  
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jbc.org/content/295/17/5626.full
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A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability

1
1. scibot 04 Sep 2020
  
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  Addgene12260
  
  DOI: 10.1016/j.celrep.2020.01.020
  
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sciencedirect.com/science/article/pii/S2211124720300292
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TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells

1
1. scibot 03 Sep 2020
  
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  Plasmid# 12260
  
  DOI: 10.1016/j.celrep.2020.03.056
  
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sciencedirect.com/science/article/pii/S2211124720303703
www.nature.com www.nature.com

Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma

1
1. scibot 03 Sep 2020
  
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  RRID:Addgene_12260
  
  DOI: 10.1038/s41591-020-0827-2
  
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nature.com/articles/s41591-020-0827-2
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FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells

1
1. scibot 03 Sep 2020
  
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  AddgeneCat#12260
  
  DOI: 10.1016/j.immuni.2020.04.002
  
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Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria

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  plasmid #12260
  
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Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer

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  AddgeneCat#12260
  
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Challenges and Reinterpretation of Antibody-Based Research on Phosphorylation of Tyr307 on PP2Ac

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  AddgeneCat#12260
  
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Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway

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  plasmid #12260
  
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Vimentin Coordinates Protein Turnover at the Aggresome during Neural Stem Cell Quiescence Exit

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  AddgeneCat#12260
  
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The G3BP1-Family-USP10 Deubiquitinase Complex Rescues Ubiquitinated 40S Subunits of Ribosomes Stalled in Translation from Lysosomal Degradation

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  Addgene#12260
  
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MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome

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PI31 Is an Adaptor Protein for Proteasome Transport in Axons and Required for Synaptic Development

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  Addgene #12260
  
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m.3243A > G-Induced Mitochondrial Dysfunction Impairs Human Neuronal Development and Reduces Neuronal Network Activity and Synchronicity

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  RRID:Addgene_12260
  
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A Model of Differential Mammary Growth Initiation by Stat3 and Asymmetric Integrin-α6 Inheritance

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Malignant Transformation Involving CXXC4 Mutations Identified in a Leukemic Progression Model of Severe Congenital Neutropenia

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  DOI: 10.1016/j.xcrm.2020.100074
  
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Proximal Biotinylation Based Combinatory Approach for Isolating Integral Plasma Membrane Proteins

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  RRID: Addgene_12260
  
  DOI: 10.1021/acs.jproteome.0c00113
  
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Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative Stress

1
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  psPAX2
  
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Recognition of Semaphorin Proteins by P. sordellii Lethal Toxin Reveals Principles of Receptor Specificity in Clostridial Toxins

1
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  Addgene plasmid 12260
  
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Mutant p53 Drives Cancer Metastasis via RCP-Mediated Hsp90α Secretion

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  psPAX
  
  DOI: 10.1016/j.celrep.2020.107879
  
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ABC transporters control ATP release through cholesterol-dependent volume-regulated anion channel activity

1
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  Addgene plasmid 12260
  
  DOI: 10.1074/jbc.RA119.010699
  
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The small EF-hand protein CALML4 functions as a critical myosin light chain within the intermicrovillar adhesion complex

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  Addgene_12260
  
  DOI: 10.1074/jbc.RA120.012820
  
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Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis

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  RRID:Addgene_12260
  
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A Comprehensive Map of the Monocyte-Derived Dendritic Cell Transcriptional Network Engaged upon Innate Sensing of HIV

1
1. scibot 31 Aug 2020
  
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  Addgene plasmid #12260
  
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A Three-Dimensional Alzheimer’s Disease Cell Culture Model Using iPSC-Derived Neurons Carrying A246E Mutation in PSEN1

1
1. scibot 22 Aug 2020
  
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  RRID: Addgene_12260
  
  DOI: 10.3389/fncel.2020.00151
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7325960/
Jan 2020
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eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma

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  Addgene_12260
  
  DOI: 10.1038/s41467-019-13086-5
  
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Cell-Cycle Asynchrony Generates DNA Damage at Mitotic Entry in Polyploid Cells

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  RRID:Addgene_12260
  
  DOI: 10.1016/j.cub.2019.09.041
  
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TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling

1
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  RRID:Addgene_12260
  
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Cysteine catabolism and the serine biosynthesis pathway support pyruvate production during pyruvate kinase knockdown in pancreatic cancer cells

1
1. scibot 13 Jan 2020
  
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  plasmid_12260
  
  DOI: 10.1186/s40170-019-0205-z
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6937848/
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Integrin-α3 Is a Functional Marker of Ex Vivo Expanded Human Long-Term Hematopoietic Stem Cells

1
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.celrep.2019.06.084
  
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A MYC–GCN2–eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer

1
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  RRID:Addgene_12260
  
  DOI: 10.1038/s41556-019-0408-0
  
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nature.com/articles/s41556-019-0408-0
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PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression

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  RRID:Addgene_12260
  
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Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle

1
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  RRID:Addgene_12260
  
  DOI: 10.7554/eLife.50087
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6890464/
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Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity

1
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  RRID:Addgene_12260
  
  DOI: 10.7554/eLife.47498
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6739868/
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Essential thrombocytosis attributed to <Emphasis Type="Italic">JAK2</Emphasis>-T875N germline mutation

1
1. scibot 13 Jan 2020
  
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  plasmid_12260
  
  DOI: 10.1007/s12185-019-02725-8
  
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Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade

1
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  RRID:Addgene_12260
  
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Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome

1
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.ccell.2019.06.007
  
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Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy

1
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.celrep.2019.08.105
  
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sciencedirect.com/science/article/pii/S2211124719311672
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Id4 Downstream of Notch2 Maintains Neural Stem Cell Quiescence in the Adult Hippocampus

1
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.celrep.2019.07.014
  
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HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice

1
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.ccell.2019.10.011
  
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Circular RNA circPICALM sponges miR-1265 to inhibit bladder cancer metastasis and influence FAK phosphorylation

1
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.ebiom.2019.08.074
  
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Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling

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ATG5 cancer mutations and alternative mRNA splicing reveal a conjugation switch that regulates ATG12–ATG5-ATG16L1 complex assembly and autophagy

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Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells

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Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection

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BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis

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MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat

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Elevated Heme Synthesis and Uptake Underpin Intensified Oxidative Metabolism and Tumorigenic Functions in Non–Small Cell Lung Cancer Cells

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Host signaling and EGR1 transcriptional control of human cytomegalovirus replication and latency

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Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21

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FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy

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Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer

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Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia

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Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5

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Evaluation of reference genes for quantitative real-time PCR in Wharton’s Jelly-derived mesenchymal stem cells after lentiviral transduction and differentiation

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Stimulation of Piezo1 by mechanical signals promotes bone anabolism

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MIGA2 Links Mitochondria, the ER, and Lipid Droplets and Promotes De Novo Lipogenesis in Adipocytes

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Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer

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Widespread and Functional RNA Circularization in Localized Prostate Cancer

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Longitudinal Analysis of the Human B Cell Response to Ebola Virus Infection

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Transmembrane 4 L Six Family Member 5 Senses Arginine for mTORC1 Signaling

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Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology

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Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells

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Design and construction of a recombinant lentiviral vector with specific tropism to human epidermal growth factor‐overexpressed cancer cells: developing a new retargeting system for lentivirus vectors

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Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR

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MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance

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A Neuron-Optimized CRISPR/dCas9 Activation System for Robust and Specific Gene Regulation

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  SciCrunch record: plasmid_12260
  
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  RRID:Addgene_12260 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:Addgene_12260

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590918305927
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:Addgene_12260
  
  DOI: 10.7554/eLife.43511
  
  Resource: RRID:Addgene_12260
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_12260
  
  What is this?
  
  RRID:Addgene_12260 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:Addgene_12260

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6414201/
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:Addgene_12260
  
  DOI: 10.1016/j.stem.2019.02.006
  
  Resource: RRID:Addgene_12260
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_12260
  
  What is this?
  
  RRID:Addgene_12260 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:Addgene_12260

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590919300487
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 12 Jan 2020
  
  in Public
  
  Addgene_12260
  
  DOI: 10.1016/j.immuni.2018.11.013
  
  Resource: RRID:Addgene_12260
  
  Curator: @ethanbadger
  
  SciCrunch record: Addgene_12260
  
  What is this?
  
  RRID:Addgene_12260 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:Addgene_12260

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761318304953

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