4,692 Matching Annotations
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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LIG1 Loss in TP53-mutant Triple Negative Breast Cancer Rewires DNA Repair and Confers Sensitivity to PARP-ATR Inhibitor Combinations
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    pmc.ncbi.nlm.nih.gov/articles/PMC13482947/
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    STRA6-mediated ferroptosis and its potential association with antioxidant stress pathways in glioblastoma
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    sciencedirect.com/science/article/pii/S2589004226024089
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    A NEK2/ZWINT–NDC80 regulatory axis drives bladder cancer progression and chemoresistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC13490343/
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    An inflammatory bowel disease-linked lncRNA suppresses transcription factor T-BET expression in T cells to limit intestinal inflammation
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    sciencedirect.com/science/article/pii/S1074761326003183
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    Chrysosplenetin-induced TMED3 aggregation triggers unfolded protein response in pancreatic cancer
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    link.springer.com/article/10.1038/s44321-026-00506-5
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    Brain assembloids reveal efficacy and off target effects in high grade glioma brain cancer
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    sciencedirect.com/science/article/pii/S2589004226026258
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    Tumors exploit interclonal Hedgehog-Wnt crosstalk to drive tumor-promoting cell competition
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    sciencedirect.com/science/article/pii/S153458072600287X
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    ER-liquid condensate contacts sequester FAM134B/C and RhoA to govern cell morphology
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    sciencedirect.com/science/article/pii/S1097276526005137
  10. Aug 2026
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    Polyamines buffer labile iron to suppress ferroptosis
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    sciencedirect.com/science/article/pii/S009286742600872X
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    AURORA A interacts with DICER and SETD2 to promote S-phase progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC13458143/
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    C-terminal lysine residues localise NLRP10 at lipid droplets and govern NLRP10 oligomer formation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13458767/
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    The regulation of protein phosphatase 4 by FBXO42 is required for cancer cell survival
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    pmc.ncbi.nlm.nih.gov/articles/PMC13458699/
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    Canonical and isomiR products of miR-142 enhance dendritic cell reprogramming
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    sciencedirect.com/science/article/pii/S2211124726009034
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    Spi-B and IRF1 activate tumor immunogenicity downstream of the Epstein-Barr virus protein LMP1
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    sciencedirect.com/science/article/pii/S2211124726009022
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    FOXA1 drives chemoresistance through activating Wnt pathway in small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13458387/
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    Lipidomic profiling reveals age-dependent changes in plasma membrane lipids that affect neural stem cell aging
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    science.org/doi/10.1126/sciadv.aeh9771
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    Transcriptome-wide splicing analysis reveals HuR-regulated post-transcriptional programs in osteocytes
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    sciencedirect.com/science/article/pii/S2589004226019048
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    Latent effector T cells mediate immunotherapy responses in the bone marrow microenvironment
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    sciencedirect.com/science/article/pii/S1535610826003491
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    Bio-Inspired Biopolymeric Implantable Platform for Localized and Sustained Drug Delivery in Solid Tumor Treatment
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adfm.77242
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    CRISPR activation screens identify oncogenic lncRNAs that are susceptible to CDK4/6 inhibitor treatment
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    PKR engages viral RNA and intron-retained host transcripts during poxvirus infection
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    sciencedirect.com/science/article/pii/S2211124726009162
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    Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes
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    Integrative 3D genome and epigenomic analysis identifies TP53RK and SYBU as critical regulators of stemness and anti-tumor immunity in HCC
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    sciencedirect.com/science/article/pii/S2211124726008752
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    ZNF469 drives TGF-β1/SMAD3-mediated extracellular matrix regulation in pulmonary fibrosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13394613/
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    Fibroblast growth factor receptor substrate 2 interactome mapping reveals novel candidate interactors associated with migration and invasion
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    Complement factor B deficiency promotes lung cancer progression via FOS-mediated tryptophan metabolism and immune suppression
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    pmc.ncbi.nlm.nih.gov/articles/PMC13389098/
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    Mitochondrial l-2-hydroxyglutarate is a physiological signalling metabolite
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  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preformed fibrils of α-synuclein rapidly activate LRRK2 on early endosomes, driving Rab5 phosphorylation and disrupting endolysosomal and synaptic function
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    Mevalonate pathway rewiring driven by enhancer remodelling confers resistance to KRAS inhibitors in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13392262/
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    A dual-pronged host-directed therapeutic targeting cyclophilin A and pathogenic interferon response abrogates virus-triggered pregnancy pathologies
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    COXFA4L2 upregulation preserves residual cytochrome c oxidase activity in COXFA4-related Leigh-like encephalopathy
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    Initial leukemic epigenomic state determines hypomethylating agent response
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    pmc.ncbi.nlm.nih.gov/articles/PMC13388667/
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    Distinct roles of MCM2-7 subunits in replication licensing in human cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13388693/
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    Pink1-mediated mitophagy in the endothelium releases proteins encoded by mitochondrial DNA and activates neutrophil responses during inflammation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13423353/
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    SGEF coordinates epithelial morphogenesis by regulating junction stability, collective migration, and extracellular matrix remodeling
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    The basal cell state maintains pancreatic cancers by controlling an immunosuppressive circuit
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    pmc.ncbi.nlm.nih.gov/articles/PMC13404871/
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    The Nematicide Tioxazafen Disrupts Proteasome Function via Cytochrome P450 Bioactivation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13405185/
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    NNMT Loss Drives Cancer Progression by enhancing SAM availability for mTORC1 Signaling and Chromatin Methylation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13430563/
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    PCSK9 alleviates doxorubicin-induced pyroptosis of cardiomyocytes
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    HBx Downregulates TFEB via the CUL4A/CUL4B–DDB1 Axis to Disrupt Lysosomal Function in Hepatocellular Carcinoma Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13406449/
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    Posaconazole mitigates α-amanitin-induced liver injury by inhibiting STT3B-mediated glycosylation and cellular uptake
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    pmc.ncbi.nlm.nih.gov/articles/PMC13395608/
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    Protocol for Measuring Drug–Target Engagement in Mouse Colorectal Cancer Organoids Using NanoBRET Assay
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    pmc.ncbi.nlm.nih.gov/articles/PMC13403122/
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    EMT activates ER-to-Golgi trafficking through upregulation of REEP2 to promote lung cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC13419587/
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    U2AF2-regulated alternative splicing of UPP1 promotes NSCLC progression by enhancing glycolysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13412370/
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    Multi-omic screening identifies RBMXL3 as a primate-specific RNA-binding protein and candidate regulator of RNA metabolism in human spermatogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13404310/
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    Targeting TOMM40 unleashes immunogenic mitophagy to facilitate antigen presentation and immunotherapy sensitization
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    pmc.ncbi.nlm.nih.gov/articles/PMC13409098/
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    Systems analysis reveals alternate metabolic states adopted by Mycobacterium tuberculosis across species
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    Strain-specific epistasis shapes fitness landscapes of APOBEC3G antagonism by HIV-1 Vif proteins
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    pmc.ncbi.nlm.nih.gov/articles/PMC13394466/
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    ERRγ impedes neuroendocrine prostate cancer development
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    Perturb-seq reveals TCF7 as a transcriptional link between MAPK- and Wnt-driven gene expression
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    BET inhibition curbs macrophage inflammation, lipid accumulation, and atherogenesis by disrupting the YAP/TAZ-BRD4 axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13412306/
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    RHOA controls oncogenic B cell receptor signaling in aggressive lymphoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12867627/
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    Adapting upright light sheet fluorescence microscopy for imaging at air-liquid interface
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    Pyoderma gangrenosum caused by the molecular uncoupling of OTULIN catalytic activity and LUBAC binding
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    Functional analysis of O-GlcNAcylation by networking of OGT interactors and substrates
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    Establishment of an immortalized erythroid model for Hb Bart’s hydrops fetalis with homozygous α0-thalassemia Southeast Asian deletion
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    pmc.ncbi.nlm.nih.gov/articles/PMC13408849/
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    Mycobacterium tuberculosis IDH-PPARγ interaction suppresses GPX4 to drive macrophage ferroptosis and sustain persistent infection
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    pmc.ncbi.nlm.nih.gov/articles/PMC13402603/
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    AMC-F1 regulates mitochondria-autophagy crosstalk independent of nutrient stress
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    Macrophage-derived fibronectin suppresses antitumor immunity via tissue stiffening and immunosuppressive cell induction in cancer mouse models
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    TRMT1-mediated tRNA m22G modification drives Osimertinib resistance via the ATXN3/USP25 axis in lung adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13408171/
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    Multi-omics profiling unveils biological and clinical insights into pulmonary sarcomatoid carcinoma
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    Intermediate filament protein vimentin propels intrahepatic lipid accumulation in insulin-resistant mice
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    LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis
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    SNHG15 Positively Regulates Influenza Virus Infection Through Its Association With miR‐153 and RABL2A
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    pmc.ncbi.nlm.nih.gov/articles/PMC13396821/
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    Cdk7 Regulates Myelin Sheath Morphology and Lipid Homeostasis in Schwann Cells
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    Orthogonal CRISPR screens and human liver chimeric mice identify hepatitis B virus host factors
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    A machine learning model predicts protein stability of annotated and alternate protein isoforms
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    Mitochondrial Abundant Heat Soluble (MAHS) Protein Expression Modulates Metabolic Dynamics in Human Adipose-Derived Stem Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13412036/
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    A comprehensive map of missense trafficking variants in rhodopsin and their response to pharmacologic correction
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    pmc.ncbi.nlm.nih.gov/articles/PMC13418928/
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    De novo design of quasisymmetric two-component protein cages
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    pmc.ncbi.nlm.nih.gov/articles/PMC13412984/
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    LRP4 is an entry receptor for multiple encephalitic alphaviruses
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    pmc.ncbi.nlm.nih.gov/articles/PMC13402676/
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    MYOD1 mutation drives cancer stem cell pathways and therapy-resistance in spindle cell/sclerosing rhabdomyosarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13396186/
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    Inhibitory TIGIT signaling is dependent on T cell receptor activation
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    sciencedirect.com/science/article/pii/S221112472600865X
  76. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of SETD2-mediated H3K36me3 Drives CD8+ T Cell Exhaustion in Lung Cancer through CXCL-dependent PMN-MDSC Recruitment and Arginine Deprivation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13438026/
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    The transmembrane segments of SARS-CoV-2 nsp3 govern viral intracellular trafficking
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    pmc.ncbi.nlm.nih.gov/articles/PMC13435465/
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    HER2 heterogeneous breast cancer models reveal novel therapeutic targets and subclonal dynamics during evolution to resistance to HER2-targeted therapies
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    pmc.ncbi.nlm.nih.gov/articles/PMC13430225/
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    Cell type-dependent induction of type I interferon and PARP1 activation in astrocytes and neurons during chikungunya virus infection
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    pmc.ncbi.nlm.nih.gov/articles/PMC13435702/
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    VPS33A and VPS18 orchestrate porcine epidemic diarrhea virus replication by modulating autophagic flux
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    pmc.ncbi.nlm.nih.gov/articles/PMC13432860/
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TRIM21-mediated ubiquitination of PARP1 regulated by the PI3K/AKT-STAT5A axis suppresses small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13434705/
  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Runx1 and Runx2 act in concert to suppress Wnt/β-catenin-driven mammary tumourigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13427844/
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SETDB1-mediated repression of RhoB promotes EMT and metastatic progression in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13433250/
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immunophenotype and proviral landscape of HTLV-1c infection and pulmonary disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC13427564/
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13399593/
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    Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13441298/
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fluorescent Powassan Reporter Viruses Infect Neuron, Astrocyte and Microglial Cell Lines Independent of Attenuating D308N Envelope Protein Modification
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