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844 Matching Annotations

Feb 2022
elifesciences.org elifesciences.org

Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes

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1. scibot 19 Feb 2022
  
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  DOI: 10.7554/eLife.70714
  
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elifesciences.org/articles/70714
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Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth

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1. scibot 13 Feb 2022
  
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  DOI: 10.1016/j.medj.2021.12.008
  
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sciencedirect.com/science/article/pii/S2666634021004098
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E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression

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1. scibot 04 Feb 2022
  
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  DOI: 10.1016/j.molcel.2022.01.002
  
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sciencedirect.com/science/article/pii/S1097276522000028
Jan 2022
www.cell.com www.cell.com

Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect pre-mRNA processing

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1. scibot 26 Jan 2022
  
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  DOI: 10.1016/j.molcel.2021.12.023
  
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cell.com/molecular-cell/fulltext/S1097-2765(21)01085-6
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Type I and II PRMTs inversely regulate post-transcriptional intron detention through Sm and CHTOP methylation

1
1. scibot 22 Jan 2022
  
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  DOI: 10.7554/eLife.72867
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8765754/
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Histone acetyltransferase NAA40 modulates acetyl-CoA levels and lipid synthesis

1
1. scibot 22 Jan 2022
  
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  DOI: 10.1186/s12915-021-01225-8
  
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link.springer.com/article/10.1186/s12915-021-01225-8
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Chromatin alterations during the epididymal maturation of mouse sperm refine the paternally inherited epigenome

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1. scibot 08 Jan 2022
  
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  DOI: 10.1186/s13072-021-00433-4
  
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link.springer.com/article/10.1186/s13072-021-00433-4
Dec 2021
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EMSY inhibits homologous recombination repair and the interferon response, promoting lung cancer immune evasion

1
1. scibot 28 Dec 2021
  
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  DOI: 10.1016/j.cell.2021.12.005
  
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sciencedirect.com/science/article/pii/S0092867421014276
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IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer

1
1. scibot 22 Dec 2021
  
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  DOI: 10.1016/j.celrep.2021.110138
  
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sciencedirect.com/science/article/pii/S221112472101634X
www-sciencedirect-com.proxy.library.vcu.edu www-sciencedirect-com.proxy.library.vcu.edu

Potent macrocycle inhibitors of the human SAGA deubiquitinating module

1
1. scibot 22 Dec 2021
  
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  DOI: 10.1016/j.chembiol.2021.12.004
  
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www-sciencedirect-com.proxy.library.vcu.edu/science/article/pii/S2451945621005183
www.nature.com www.nature.com

Evolution of a histone variant involved in compartmental regulation of NAD metabolism

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1. scibot 15 Dec 2021
  
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  DOI: 10.1038/s41594-021-00692-5
  
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nature.com/articles/s41594-021-00692-5
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pharmacological targeting of Sam68 functions in colorectal cancer stem cells

1
1. scibot 11 Dec 2021
  
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  DOI: 10.1016/j.isci.2021.103442
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8633986/
www.cell.com www.cell.com

MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”

1
1. scibot 10 Dec 2021
  
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  DOI: 10.1016/j.molcel.2021.11.016
  
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cell.com/molecular-cell/fulltext/S1097-2765(21)00996-5
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The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability

1
1. scibot 09 Dec 2021
  
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  DOI: 10.1016/j.celrep.2021.110080
  
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sciencedirect.com/science/article/pii/S2211124721015710
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Methods to separate nuclear soluble fractions reflecting localizations in living cells

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1. scibot 08 Dec 2021
  
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  RRID:AB_302613
  
  DOI: 10.1016/j.isci.2021.103503
  
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sciencedirect.com/science/article/pii/S2589004221014747
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SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity

1
1. scibot 07 Dec 2021
  
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  DOI: 10.1016/j.molcel.2021.11.011
  
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sciencedirect.com/science/article/pii/S1097276521009904
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sumoylation of the human histone H4 tail inhibits p300-mediated transcription by RNA polymerase II in cellular extracts

1
1. scibot 01 Dec 2021
  
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  DOI: 10.7554/eLife.67952
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8626089/
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Ago1 controls myogenic differentiation by regulating eRNA-mediated CBP-guided epigenome reprogramming

1
1. scibot 01 Dec 2021
  
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  DOI: 10.1016/j.celrep.2021.110066
  
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sciencedirect.com/science/article/pii/S2211124721015527
Nov 2021
www.cell.com www.cell.com

MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts

1
1. scibot 30 Nov 2021
  
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  RRID:AB_302613
  
  DOI: 10.1016/j.molcel.2021.11.002
  
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cell.com/molecular-cell/fulltext/S1097-2765(21)00952-7
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Transcription-wide mapping of dihydrouridine reveals that mRNA dihydrouridylation is required for meiotic chromosome segregation

1
1. scibot 19 Nov 2021
  
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  DOI: 10.1016/j.molcel.2021.11.003
  
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sciencedirect.com/science/article/pii/S1097276521009539
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Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1

1
1. scibot 12 Nov 2021
  
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  DOI: 10.1016/j.molcel.2021.10.015
  
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sciencedirect.com/science/article/pii/S1097276521009072
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Acetyl-CoA derived from hepatic mitochondrial fatty acid β-oxidation aggravates inflammation by enhancing p65 acetylation

1
1. scibot 09 Nov 2021
  
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  RRID:AB_302613
  
  DOI: 10.1016/j.isci.2021.103244
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8551082/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

DDK/Hsk1 phosphorylates and targets fission yeast histone deacetylase Hst4 for degradation to stabilize stalled DNA replication forks

1
1. scibot 09 Nov 2021
  
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  RRID:AB_302613
  
  DOI: 10.7554/eLife.70787
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8565929/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A role for SMARCB1 in synovial sarcomagenesis reveals that SS18-SSX induces canonical BAF destruction

1
1. scibot 09 Nov 2021
  
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  RRID:AB_302613
  
  DOI: 10.1158/2159-8290.CD-20-1219
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8567602/
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Glut1 expression in tumor-associated neutrophils promotes lung cancer growth and resistance to radiotherapy

1
1. scibot 05 Nov 2021
  
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  RRID:AB_302613
  
  DOI: 10.1158/0008-5472.CAN-20-2870
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8137580/
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Identification of the sex-determining factor in the liverwort Marchantia polymorpha reveals unique evolution of sex chromosomes in a haploid system

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1. scibot 04 Nov 2021
  
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  DOI: 10.1016/j.cub.2021.10.023
  
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sciencedirect.com/science/article/pii/S0960982221014123
Oct 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination

1
1. scibot 28 Oct 2021
  
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  RRID:AB_302613
  
  DOI: 10.1038/s41467-021-26079-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8484605/
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The BORDER family of negative transcription elongation factors regulates flowering time in Arabidopsis

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1. scibot 19 Oct 2021
  
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  DOI: 10.1016/j.cub.2021.09.074
  
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sciencedirect.com/science/article/pii/S0960982221013427
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A viral histone-like protein exploits antagonism between linker histones and HMGB proteins to obstruct the cell cycle

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1. scibot 19 Oct 2021
  
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  DOI: 10.1016/j.cub.2021.09.050
  
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sciencedirect.com/science/article/pii/S0960982221012902
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Gene bookmarking by the heat shock transcription factor programs the insulin-like signaling pathway

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1. scibot 14 Oct 2021
  
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  DOI: 10.1016/j.molcel.2021.09.022
  
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sciencedirect.com/science/article/pii/S1097276521007759
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NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain

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1. scibot 12 Oct 2021
  
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  DOI: 10.1016/j.molcel.2021.09.020
  
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sciencedirect.com/science/article/pii/S1097276521007541
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PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation

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1. scibot 06 Oct 2021
  
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  DOI: 10.1016/j.celrep.2021.109776
  
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sciencedirect.com/science/article/pii/S2211124721012304
Sep 2021
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H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity

1
1. scibot 28 Sep 2021
  
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  DOI: 10.1016/j.devcel.2021.09.001
  
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sciencedirect.com/science/article/pii/S1534580721006821
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A hydride transfer complex reprograms NAD metabolism and bypasses senescence

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1. scibot 23 Sep 2021
  
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  DOI: 10.1016/j.molcel.2021.08.028
  
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sciencedirect.com/science/article/pii/S109727652100695X
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DOT1L O-GlcNAcylation promotes its protein stability and MLL-fusion leukemia cell proliferation

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1. scibot 22 Sep 2021
  
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  DOI: 10.1016/j.celrep.2021.109739
  
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sciencedirect.com/science/article/pii/S221112472101192X
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The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress

1
1. scibot 16 Sep 2021
  
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  DOI: 10.1016/j.celrep.2021.109694
  
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Independent transcriptomic and proteomic regulation by type I and II protein arginine methyltransferases

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Hybrid protein assembly-histone modification mechanism for PRC2-based epigenetic switching and memory

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Splicing modulators elicit global translational repression by condensate-prone proteins translated from introns

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Linker histone H1.8 inhibits chromatin binding of condensins and DNA topoisomerase II to tune chromosome length and individualization

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Reshaping of the androgen-driven chromatin landscape in normal prostate cells by early cancer drivers and effect on therapeutic sensitivity

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UV-induced reduction in Polycomb repression promotes epidermal pigmentation

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Mutant U2AF1-induced alternative splicing of H2afy (macroH2A1) regulates B-lymphopoiesis in mice

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Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration

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Fatty acids impact sarcomere integrity through myristoylation and ER homeostasis

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HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness

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Feedback repression of PPARα signaling by Let-7 microRNA

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Epigenetic Dysregulation Induces Translocation of Histone H3 into Cytoplasm

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miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to impact proteotoxicity and muscle function during aging

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DNA Damage Signaling-Induced Cancer Cell Reprogramming as a Driver of Tumor Relapse

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UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

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Systematic Functional Annotation of Somatic Mutations in Cancer

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Mechanism and function of DNA replication-independent DNA-protein crosslink repair via the SUMO-RNF4 pathway

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KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance

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The Splicing Factor hnRNP M Is a Critical Regulator of Innate Immune Gene Expression in Macrophages

1
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  Rabbit polyclonal Histone 3
  
  DOI: 10.1016/j.celrep.2019.09.078
  
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Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution

1
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Interrogating Histone Acetylation and BRD4 as Mitotic Bookmarks of Transcription

1
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NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress

1
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  rabbit polyclonal anti-histone H3
  
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Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State

1
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  Rabbit polyclonal anti-H3
  
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Nuclear PGK1 Alleviates ADP-Dependent Inhibition of CDC7 to Promote DNA Replication

1
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Genome-wide Rules of Nucleosome Phasing in Drosophila

1
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Genetic Interactions between the Aurora Kinases Reveal New Requirements for AURKB and AURKC during Oocyte Meiosis

1
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ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures

1
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PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation

1
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Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation

1
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Tanshinone IIA Restores Dynamic Balance of Autophagosome/Autolysosome in Doxorubicin-Induced Cardiotoxicity via Targeting Beclin1/LAMP1

1
1. scibot 29 Jul 2021
  
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  anti-histone H3
  
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  DOI: 10.1016/j.molcel.2017.05.026
  
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Combinatorial Targeting by MicroRNAs Co-ordinates Post-transcriptional Control of EMT

1
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  AB_302613
  
  DOI: 10.1016/j.cels.2018.05.019
  
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Proteasome storage granules protect proteasomes from autophagic degradation upon carbon starvation

2
1. scibot 29 Jul 2021
  
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  RRID:AB_302613
  
  DOI: 10.7554/eLife.34532
  
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2. scibot 27 Jul 2021
  
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Multi-omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency

2
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DNA Damage Signaling-Induced Cancer Cell Reprogramming as a Driver of Tumor Relapse

1
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A chemical toolbox for the study of bromodomains and epigenetic signaling

1
1. scibot 28 Jul 2021
  
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  anti-H3
  
  DOI: 10.1038/s41467-019-09672-2
  
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Untitled document

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  DOI: 10.1093/nar/gky232
  
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Widespread Accumulation of Ribosome-Associated Isolated 3′ UTRs in Neuronal Cell Populations of the Aging Brain

1
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  RRID:AB_302613
  
  DOI: 10.1016/j.celrep.2018.10.094
  
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The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage

1
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  AB_302613
  
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Systematic Functional Annotation of Somatic Mutations in Cancer

1
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Species specific differences in use of ANP32 proteins by influenza A virus

1
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  AB_1791
  
  DOI: 10.7554/eLife.45066
  
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The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation

1
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  RRID:GR1240576-1
  
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  DOI: 10.1016/j.ccell.2018.11.008
  
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VAL genes regulate vegetative phase change via miR156-dependent and independent mechanisms

1
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Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination

1
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  DOI: 10.1016/j.molcel.2021.06.016
  
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The Polycomb group protein MEDEA controls cell proliferation and embryonic patterning in Arabidopsis

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1. scibot 30 Jun 2021
  
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  RRID:AB_302613
  
  DOI: 10.1016/j.devcel.2021.06.004
  
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The nuclear kinesin KIF18B promotes 53BP1-mediated DNA double-strand break repair

1
1. scibot 30 Jun 2021
  
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  RRID:AB_302613
  
  DOI: 10.1016/j.celrep.2021.109306
  
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BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation

2
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  RRID:AB_302613
  
  DOI: 10.1016/j.molcel.2021.06.020
  
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  AB_1791
  
  DOI: 10.1016/j.molcel.2021.06.020
  
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Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin

1
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  AB_302613
  
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A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing

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  DOI: 10.7554/eLife.62233
  
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Programmed suppression of oxidative phosphorylation and mitochondrial function by gestational alcohol exposure correlate with widespread increases in H3K9me2 that do not suppress transcription

1
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  RRID:AB_302613
  
  DOI: 10.1186/s13072-021-00403-w
  
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Correct dosage of X chromosome transcription is controlled by a nuclear pore component

1
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  RRID:AB_302613
  
  DOI: 10.1016/j.celrep.2021.109236
  
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XRCC1 prevents toxic PARP1 trapping during DNA base excision repair

1
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  RRID:AB_302613
  
  DOI: 10.1016/j.molcel.2021.05.009
  
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Cystatin B-deficiency triggers ectopic histone H3 tail cleavage during neurogenesis

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  DOI: 10.1016/j.nbd.2021.105418
  
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Boundaries potentiate polycomb response element-mediated silencing

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  RRID:AB_302613
  
  DOI: 10.1186/s12915-021-01047-8
  
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Uncovering the RNA-binding protein landscape in the pluripotency network of human embryonic stem cells

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1. scibot 02 Jun 2021
  
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  RRID:AB_302613
  
  DOI: 10.1016/j.celrep.2021.109198
  
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Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets

1
1. scibot 02 Jun 2021
  
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May 2021
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Guiding functions of the C-terminal domain of topoisomerase IIα advance mitotic chromosome assembly

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1. scibot 22 May 2021
  
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  DOI: 10.1038/s41467-021-23205-w
  
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nature.com/articles/s41467-021-23205-w
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Suppression of β-catenin signaling in colon carcinoma cells by a bacterial protein

1
1. scibot 20 May 2021
  
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  rabbit polyclonal anti-histone H3
  
  DOI: 10.1002/ijc.33562
  
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Human telomerase is directly regulated by non-telomeric TRF2-G-quadruplex interaction

1
1. scibot 19 May 2021
  
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  DOI: 10.1016/j.celrep.2021.109154
  
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CloneSeq: A highly sensitive analysis platform for the characterization of 3D-cultured single-cell-derived clones

1
1. scibot 19 May 2021
  
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  RRID:AB_302613
  
  DOI: 10.1016/j.devcel.2021.04.026
  
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The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer

1
1. scibot 18 May 2021
  
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  RRID:AB_302613
  
  DOI: 10.1016/j.cell.2021.04.022
  
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DHODH inhibition modulates glucose metabolism and circulating GDF15, and improves metabolic balance

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1. scibot 14 May 2021
  
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  RRID:AB_302613
  
  DOI: 10.1016/j.isci.2021.102494
  
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Missense mutations in small muscle protein X-linked ( SMPX ) cause distal myopathy with protein inclusions

1
1. scibot 12 May 2021
  
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  RRID:AB_302613
  
  DOI: 10.1007/s00401-021-02319-x
  
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Methylation of histone H3 at lysine 37 by Set1 and Set2 prevents spurious DNA replication

1
1. scibot 12 May 2021
  
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  DOI: 10.1016/j.molcel.2021.04.021
  
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Inhibition of miR-155 potentially protects Lipopolysaccharide-induced acute lung injury through the IRF2BP2-NFAT1 pathway

1
1. scibot 10 May 2021
  
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  RRID:AB_302613
  
  DOI: 10.1152/ajpcell.00116.2020
  
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Spermiogenic histone transitions and chromatin decondensation in Decapoda

1
1. scibot 09 May 2021
  
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  AB_302613
  
  DOI: 10.1016/j.theriogenology.2020.07.003
  
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Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes

1
1. scibot 09 May 2021
  
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  RRID:AB_302613
  
  DOI: 10.1016/j.stem.2020.12.016
  
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Histone crotonylation promotes mesoendodermal commitment of human embryonic stem cells

1
1. scibot 09 May 2021
  
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  DOI: 10.1016/j.stem.2020.12.009
  
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Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation

1
1. scibot 09 May 2021
  
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  RRID:AB_302613
  
  DOI: 10.1016/j.stem.2020.06.005
  
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Ubiquitin Phosphorylation at Thr12 Modulates the DNA Damage Response

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  DOI: 10.1016/j.molcel.2020.09.017
  
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PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells

1
1. scibot 07 May 2021
  
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  RRID:AB_302613
  
  DOI: 10.1016/j.molcel.2020.08.018
  
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HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis

1
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  RRID:AB_302613
  
  DOI: 10.1016/j.molcel.2020.04.031
  
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Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas

1
1. scibot 07 May 2021
  
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  RRID:AB_302613
  
  DOI: 10.1016/j.immuni.2020.11.002
  
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A Hyper-IgM Syndrome Mutation in Activation-Induced Cytidine Deaminase Disrupts G-Quadruplex Binding and Genome-wide Chromatin Localization

1
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  RRID:AB_302613
  
  DOI: 10.1016/j.immuni.2020.10.003
  
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A Prion-like Domain in Transcription Factor EBF1 Promotes Phase Separation and Enables B Cell Programming of Progenitor Chromatin

1
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  RRID:AB_302613
  
  DOI: 10.1016/j.immuni.2020.10.009
  
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Homology-directed repair protects the replicating genome from metabolic assaults

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  DOI: 10.1016/j.devcel.2021.01.011
  
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sciencedirect.com/science/article/pii/S1534580721000691
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FEBS Press

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  RRID:AB_302613
  
  DOI: 10.1002/1878-0261.12953
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.12953
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Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains

1
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  DOI: 10.1016/j.molcel.2021.04.012
  
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H3K27ac bookmarking promotes rapid post-mitotic activation of the pluripotent stem cell program without impacting 3D chromatin reorganization

1
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  DOI: 10.1016/j.molcel.2021.02.032
  
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STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcoma

1
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Splice site m6A methylation prevents binding of U2AF35 to inhibit RNA splicing

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SIRT6-CBP-dependent nuclear Tau accumulation and its role in protein synthesis

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High-Throughput Discovery and Characterization of Human Transcriptional Effectors

2
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Dioctatin Activates ClpP to Degrade Mitochondrial Components and Inhibits Aflatoxin Production

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Human placental cytotrophoblast epigenome dynamics over gestation and alterations in placental disease

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Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma

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FANCM regulates repair pathway choice at stalled replication forks

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Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia

1
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Thyroid Hormone-Regulated Expression of Period2 Promotes Liver Urate Production

1
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  DOI: 10.3389/fcell.2021.636802
  
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The 7SK/P-TEFb snRNP controls ultraviolet radiation-induced transcriptional reprogramming

1
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DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network

1
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MLL3 suppresses tumorigenesis through regulating TNS3 enhancer activity

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  DOI: 10.1038/s41419-021-03647-2
  
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nature.com/articles/s41419-021-03647-2
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Excess histone H3 is a competitive Chk1 inhibitor that controls cell-cycle remodeling in the early Drosophila embryo

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Deficiency of histone methyltransferase SETD2 in liver leads to abnormal lipid metabolism and hepatocarcinoma

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Evaluating DNA damage response through immunofluorescence staining of primordial germ cells in Caenorhabditis elegans L1 larva

1
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  DOI: 10.1016/j.xpro.2021.100441
  
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The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr

1
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Progesterone and estrogen regulate NALCN expression in human myometrial smooth muscle cells

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Epigenomic tensor predicts disease subtypes and reveals constrained tumor evolution

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H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model

1
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HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration

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  DOI: 10.7554/eLife.61531
  
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TRPS1 drives heterochromatic origin refiring and cancer genome evolution

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CARM1 regulates replication fork speed and stress response by stimulating PARP1

1
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Mesoscale Modeling and Single-Nucleosome Tracking Reveal Remodeling of Clutch Folding and Dynamics in Stem Cell Differentiation

1
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Long non-coding RNA00844 inhibits MAPK signaling to suppress the progression of hepatocellular carcinoma by targeting AZGP1

1
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Formation of the CenH3-Deficient Holocentromere in Lepidoptera Avoids Active Chromatin

1
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  DOI: 10.1016/j.cub.2020.09.078
  
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cell.com/current-biology/abstract/S0960-9822(20)31448-2
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Prior Hypoxia Exposure Enhances Murine Microglial Inflammatory Gene Expression in vitro Without Concomitant H3K4me3 Enrichment

1
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ncbi.nlm.nih.gov/pmc/articles/PMC7575929/
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Detrimental effects of uterine disease and lipopolysaccharide on luteal angiogenesis

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  DOI: 10.1530/JOE-19-0443
  
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joe.bioscientifica.com/view/journals/joe/245/1/JOE-19-0443.xml
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Muscone suppresses inflammatory responses and neuronal damage in a rat model of cervical spondylotic myelopathy by regulating Drp1‐dependent mitochondrial fission

1
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  DOI: 10.1111/jnc.15011
  
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Serotonin signaling by maternal neurons upon stress ensures progeny survival

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  DOI: 10.7554/eLife.55246
  
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A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation

1
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Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination

1
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Comparative profiling of the synaptic proteome from Alzheimer’s disease patients with focus on the APOE genotype

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actaneurocomms.biomedcentral.com/articles/10.1186/s40478-019-0847-7
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Chromatin Organization in Early Land Plants Reveals an Ancestral Association between H3K27me3, Transposons, and Constitutive Heterochromatin

1
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  DOI: 10.1016/j.cub.2019.12.015
  
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cell.com/current-biology/abstract/S0960-9822(19)31610-0
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Competition between PRC2.1 and 2.2 subcomplexes regulates PRC2 chromatin occupancy in human stem cells

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1. scibot 24 Feb 2021
  
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  DOI: 10.1016/j.molcel.2020.11.044
  
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Persistence of RNA transcription during DNA replication delays duplication of transcription start sites until G2/M

1
1. scibot 24 Feb 2021
  
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  DOI: 10.1016/j.celrep.2021.108759
  
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The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers

1
1. scibot 11 Feb 2021
  
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  DOI: 10.1016/j.celrep.2021.108742
  
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Neuronal non-CG methylation is an essential target for MeCP2 function

1
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Tripartite suppression of fission yeast TORC1 signaling by the GATOR1-Sea3 complex, the TSC complex, and Gcn2 kinase

1
1. scibot 09 Feb 2021
  
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  DOI: 10.7554/eLife.60969
  
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elifesciences.org/articles/60969
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Deleting Mecp2 from the cerebellum rather than its neuronal subtypes causes a delay in motor learning in mice

1
1. scibot 30 Jan 2021
  
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  DOI: 10.7554/eLife.64833
  
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DCAF14 promotes stalled fork stability to maintain genome integrity

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1. scibot 28 Jan 2021
  
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  DOI: 10.1016/j.celrep.2020.108669
  
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Chk1 promotes non-homologous end joining in G1 through direct phosphorylation of ASF1A

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Proteome dynamics at broken replication forks reveal a distinct ATM-directed repair response suppressing DNA double-strand break ubiquitination

1
1. scibot 21 Jan 2021
  
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Transcription levels of a noncoding RNA orchestrate opposing regulatory and cell fate outcomes in yeast

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1. scibot 20 Jan 2021
  
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Yeast Nuak1 phosphorylates histone H3 threonine 11 in low glucose stress by the cooperation of AMPK and CK2 signaling

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ncbi.nlm.nih.gov/pmc/articles/PMC7781599/
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linc-AAM Facilitates Gene Expression Contributing to Macrophage Activation and Adaptive Immune Responses

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Zinc Finger Protein SALL4 Functions through an AT-Rich Motif to Regulate Gene Expression

1
1. scibot 07 Jan 2021
  
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Torsin ATPases influence chromatin interaction of the Torsin regulator LAP1

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ncbi.nlm.nih.gov/pmc/articles/PMC7773337/
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The ribosomal RNA m5C methyltransferase NSUN-1 modulates healthspan and oogenesis in Caenorhabditis elegans

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The Histone Methyltransferase DOT1L Is Essential for Humoral Immune Responses

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CB1R regulates soluble leptin receptor levels via CHOP, contributing to hepatic leptin resistance

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ncbi.nlm.nih.gov/pmc/articles/PMC7728447/
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H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation

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1. scibot 25 Nov 2020
  
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Protocol for Establishing Mouse Embryonic Stem Cells to Study Histone Inheritance Pattern at Single-Cell Resolution

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1. scibot 24 Nov 2020
  
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  DOI: 10.1016/j.xpro.2020.100178
  
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