627 Matching Annotations
  1. May 2021
  2. www.sciencedirect.com www.sciencedirect.com
    Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment
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    sciencedirect.com/science/article/pii/S1534580720305888
  3. Apr 2021
  4. www.sciencedirect.com www.sciencedirect.com
    Caloric Restriction Promotes Immunometabolic Reprogramming Leading to Protection from Tuberculosis
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    sciencedirect.com/science/article/pii/S1550413120306719
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    MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice
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    sciencedirect.com/science/article/pii/S1550413120307178
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    Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer
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    sciencedirect.com/science/article/pii/S1550413120305519
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    Central Ceramide Signaling Mediates Obesity-Induced Precocious Puberty
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    sciencedirect.com/science/article/pii/S1550413120305349
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    Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle
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    sciencedirect.com/science/article/pii/S1550413120304241
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    Combined Omics Approaches Reveal the Roles of Non-canonical WNT7B Signaling and YY1 in the Proliferation of Human Pancreatic Progenitor Cells
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    sciencedirect.com/science/article/pii/S2451945620303408
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    Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
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    sciencedirect.com/science/article/pii/S1535610821001185
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    Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia
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    sciencedirect.com/science/article/pii/S1535610820305419
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    Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer
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    sciencedirect.com/science/article/pii/S1097276521002641
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    Gene editing and synthetically accessible inhibitors reveal role for TPC2 in HCC cell proliferation and tumor growth
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    sciencedirect.com/science/article/pii/S2451945621000490
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Interacts With Colony-Stimulating Factor 1 Receptor (CSF1R) but Is Not Necessary for CSF1/CSF1R-Mediated Microglial Survival
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    ncbi.nlm.nih.gov/pmc/articles/PMC8027073/
  15. Mar 2021
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hericium erinaceus mycelium and its small bioactive compounds promote oligodendrocyte maturation with an increase in myelin basic protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC7985201/
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    Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma
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    sciencedirect.com/science/article/pii/S2211124721001844
  18. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15368
  19. academic.oup.com academic.oup.com
    CXCR4 signaling at the fetal-maternal interface may drive inflammation and syncytia formation during ovine pregnancy †
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    academic.oup.com/biolreprod/article/104/2/468/5952668
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    An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence
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    sciencedirect.com/science/article/pii/S1535610820306097
  21. Feb 2021
  22. www.sciencedirect.com www.sciencedirect.com
    Alternative signaling pathways from IGF1 or Insulin to Akt activation and Foxo1 nuclear efflux in adult skeletal muscle fibers
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    sciencedirect.com/science/article/pii/S0021925817503622
  23. link.springer.com link.springer.com
    Selective targeting of the androgen receptor-DNA binding domain by the novel antiandrogen SBF-1 and inhibition of the growth of prostate cancer cells
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    link.springer.com/article/10.1007/s10637-020-01050-w
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-L1 Reverse Signaling in Dermal Dendritic Cells Promotes Dendritic Cell Migration Required for Skin Immunity
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    ncbi.nlm.nih.gov/pmc/articles/PMC7688291/
  25. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    The insulin‐sensitizing effect of a single exercise bout is similar in type I and type II human muscle fibres
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP280475
  26. journals.sagepub.com journals.sagepub.com
    ErbB3 is a critical regulator of cytoskeletal dynamics in brain microvascular endothelial cells: Implications for vascular remodeling and blood-brain-barrier modulation - Limin Wu, Mohammad R Islam, Janice Lee, Hajime Takase, Shuzhen Guo, Allison M Andrews, Tetyana P Buzhdygan, Justin Mathew, Wenlu Li, Ken Arai, Eng H Lo, Servio H Ramirez, Josephine Lok, 2021
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    journals.sagepub.com/doi/abs/10.1177/0271678X20984976
  27. www.cell.com www.cell.com
    Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30836-4
  28. www.sciencedirect.com www.sciencedirect.com
    Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination
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    sciencedirect.com/science/article/pii/S2211124721000929
  29. onlinelibrary.wiley.com onlinelibrary.wiley.com
    LncRNA RP6‐65G23.1 accelerates proliferation and inhibits apoptosis via p‐ERK1/2/p‐AKT signaling pathway on keratinocytes
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    onlinelibrary.wiley.com/doi/10.1002/jcb.29685
  30. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Reduced Na+K+‐ATPase activity may reduce amino acid uptake in IUGR fetal sheep muscle despite unchanged ex vivo amino acid transporter activity
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP278933
  31. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Synergistic growth inhibition mediated by dual PI3K/mTOR pathway targeting and genetic or direct pharmacological AKT inhibition in human glioblastoma models
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14899
  32. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Insulin‐stimulated glucose uptake partly relies on p21‐activated kinase 2 (PAK2), but not PAK1, in mouse skeletal muscle
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP280294
  33. www.sciencedirect.com www.sciencedirect.com
    An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors
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    sciencedirect.com/science/article/pii/S2211124721000577
  34. www.sciencedirect.com www.sciencedirect.com
    ARHGEF3 regulates skeletal muscle regeneration and strength through autophagy
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    sciencedirect.com/science/article/pii/S2211124721000449
  35. Jan 2021
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21
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    ncbi.nlm.nih.gov/pmc/articles/PMC7778269/
  37. www.sciencedirect.com www.sciencedirect.com
    ARHGEF3 Regulates Skeletal Muscle Regeneration and Strength through Autophagy
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    sciencedirect.com/science/article/pii/S2211124720315837
  38. Dec 2020
  39. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a female rat model
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    physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.14672
  40. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Staphylococcus aureus Panton‐Valentine Leukocidin triggers an alternative NETosis process targeting mitochondria
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.201902981R
  41. www.sciencedirect.com www.sciencedirect.com
    Hetero-oligomerization of Rho and Ras GTPases Connects GPCR Activation to mTORC2-AKT Signaling
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    sciencedirect.com/science/article/pii/S2211124720314169
  42. Nov 2020
  43. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TSPAN1: A Novel Protein Involved in Head and Neck Squamous Cell Carcinoma Chemoresistance
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    pubmed.ncbi.nlm.nih.gov/33167355/
  44. Oct 2020
  45. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma
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    pubmed.ncbi.nlm.nih.gov/33086062/
  46. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    A Small-Molecule Approach to Restore a Slow-Oxidative Phenotype and Defective CaMKIIβ Signaling in Limb Girdle Muscular Dystrophy
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    pubmed.ncbi.nlm.nih.gov/33205074/
  47. www.jneurosci.org www.jneurosci.org
    Phosphorylation of eIF2α promotes Schwann cell differentiation and myelination in CMT1B mice with activated UPR
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    jneurosci.org/content/40/42/8174
  48. academic.oup.com academic.oup.com
    Mechanisms by which membrane and nuclear ER alpha inhibit adipogenesis in cells isolated from female mice
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    academic.oup.com/endo/article/161/11/bqaa175/5911730
  49. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment
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    pubmed.ncbi.nlm.nih.gov/33027668/
  50. www.sciencedirect.com www.sciencedirect.com
    MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARγ-Dependent Gene Expression
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    sciencedirect.com/science/article/pii/S2211124720312171
  51. Sep 2020
  52. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Maternal exercise attenuates the lower skeletal muscle glucose uptake and insulin secretion caused by paternal obesity in female adult rat offspring
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    pubmed.ncbi.nlm.nih.gov/32539156/
  53. www.sciencedirect.com www.sciencedirect.com
    Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer
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    sciencedirect.com/science/article/pii/S153561082030427X
  54. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    HSP90 Inhibitor, 17-DMAG, Alone and in Combination with Lapatinib Attenuates Acquired Lapatinib-Resistance in ER-positive, HER2-Overexpressing Breast Cancer Cell Line
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    pubmed.ncbi.nlm.nih.gov/32942617/
  55. diabetes.diabetesjournals.org diabetes.diabetesjournals.org
    A Single Bout of One-legged Exercise to Local Exhaustion Decreases Insulin Action in Non-exercised Muscle Leading to Decreased Whole-body Insulin Action
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    diabetes.diabetesjournals.org/content/69/4/578
  56. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Enhanced Akt/GSK‐3β/CREB signaling mediates the anti‐inflammatory actions of mGluR5 positive allosteric modulators in microglia and following traumatic brain injury in male mice
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14954
  57. www.sciencedirect.com www.sciencedirect.com
    Enhancer-Driven lncRNA BDNF-AS Induces Endocrine Resistance and Malignant Progression of Breast Cancer through the RNH1/TRIM21/mTOR Cascade
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    sciencedirect.com/science/article/pii/S2211124720307336
  58. www.sciencedirect.com www.sciencedirect.com
    Metabolic Control over mTOR-Dependent Diapause-like State
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    sciencedirect.com/science/article/pii/S1534580719310676
  59. link.springer.com link.springer.com
    Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity
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    link.springer.com/article/10.1007/s00125-020-05117-4
  60. www.sciencedirect.com www.sciencedirect.com
    Nutrient-Driven O-GlcNAcylation Controls DNA Damage Repair Signaling and Stem/Progenitor Cell Homeostasis
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    sciencedirect.com/science/article/pii/S2211124720305854
  61. www.sciencedirect.com www.sciencedirect.com
    Dissociation of Adaptive Thermogenesis from Glucose Homeostasis in Microbiome-Deficient Mice
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    sciencedirect.com/science/article/pii/S1550413120300139
  62. onlinelibrary.wiley.com onlinelibrary.wiley.com
    High‐frequency transcranial magnetic stimulation protects APP/PS1 mice against Alzheimer’s disease progress by reducing APOE and enhancing autophagy
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    onlinelibrary.wiley.com/doi/10.1002/brb3.1740
  63. www.sciencedirect.com www.sciencedirect.com
    Streptococcus pneumoniae Infection Promotes Histone H3 Dephosphorylation by Modulating Host PP1 Phosphatase
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    sciencedirect.com/science/article/pii/S2211124720302977
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    Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras
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    sciencedirect.com/science/article/pii/S1934590920300540
  65. academic.oup.com academic.oup.com
    The endothelial barrier is not rate-limiting to insulin action in the myocardium of male mice
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    academic.oup.com/endo/article/161/4/bqaa029/5760840
  66. www.sciencedirect.com www.sciencedirect.com
    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone
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    sciencedirect.com/science/article/pii/S2211124720308214
  67. elifesciences.org elifesciences.org
    Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma
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    elifesciences.org/articles/53367
  68. www.sciencedirect.com www.sciencedirect.com
    Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
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    sciencedirect.com/science/article/pii/S2211124720307440
  69. www.jneurosci.org www.jneurosci.org
    Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk
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    jneurosci.org/content/39/37/7408
  70. www.sciencedirect.com www.sciencedirect.com
    Topological Adaptation of Transmembrane Domains to the Force-Modulated Lipid Bilayer Is a Basis of Sensing Mechanical Force
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    sciencedirect.com/science/article/pii/S0960982220302013
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    Cancer causes metabolic perturbations associated with reduced insulin-stimulated glucose uptake in peripheral tissues and impaired muscle microvascular perfusion
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    sciencedirect.com/science/article/pii/S0026049520300330
  72. www.cell.com www.cell.com
    Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons
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    cell.com/cell/abstract/S0092-8674(18)31555-1
  73. link.springer.com link.springer.com
    Effects of acute aerobic, resistance and combined exercises on 24-h glucose variability and skeletal muscle signalling responses in type 1 diabetics
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    link.springer.com/article/10.1007/s00421-020-04491-6
  74. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Synthesis, biological evaluation and toxicity of novel tetrandrine analogues
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    pubmed.ncbi.nlm.nih.gov/32942071/
  75. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Acute pharmacological inhibition of matrix metalloproteinase‐9 activity during development restores perineuronal net formation and normalizes auditory processing in Fmr1 KO mice
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15037
  76. academic.oup.com academic.oup.com
    DPP-4 inhibition with anagliptin reduces lipotoxicity-induced insulin resistance and steatohepatitis in male mice
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    academic.oup.com/endo/article/161/10/bqaa139/5892311
  77. www.sciencedirect.com www.sciencedirect.com
    Tau Reduction Prevents Key Features of Autism in Mouse Models
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    sciencedirect.com/science/article/pii/S0896627320300659
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translational Physiology: Insulin signaling displayed a differential tissue-specific response to low-dose dihydrotestosterone in female mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC5966754/
  79. www.sciencedirect.com www.sciencedirect.com
    Evidence That STK19 Is Not an NRAS-dependent Melanoma Driver
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    sciencedirect.com/science/article/pii/S0092867420304761
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    Protein synthesis inhibition promotes nitric oxide generation and activation of CGKII-dependent downstream signaling pathways in the retina
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    sciencedirect.com/science/article/pii/S0167488920300902
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531
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    ncbi.nlm.nih.gov/pmc/articles/PMC7363447/
  82. www.sciencedirect.com www.sciencedirect.com
    Hyperactivation of TORC1 Drives Resistance to the Pan-HER Tyrosine Kinase Inhibitor Neratinib in HER2-Mutant Cancers
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    sciencedirect.com/science/article/pii/S1535610819305835
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    Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa1
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    sciencedirect.com/science/article/pii/S1550413120301893
  84. www.jci.org www.jci.org
    Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia
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    jci.org/articles/view/131540
  85. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14918
  86. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    β2‐adrenoceptor activation improves skeletal muscle autophagy in neurogenic myopathy
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.201902305R
  87. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival
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    pubmed.ncbi.nlm.nih.gov/32877674/
  88. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Diet Intake Control Is Indispensable for the Gluconeogenic Response to Sodium‐Glucose Cotransporter 2 Inhibition in Male Mice
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    onlinelibrary.wiley.com/doi/full/10.1111/jdi.13319
  89. academic.oup.com academic.oup.com
    Estrogen Stimulation of Pleiotrophin Enhances Osteoblast Differentiation and Maintains Bone Mass in IGFBP-2 Null Mice
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    academic.oup.com/endo/article/161/4/bqz007/5805123
  90. Aug 2020
  91. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cathepsin B inhibition blocks neurite outgrowth in cultured neurons by regulating lysosomal trafficking and remodeling
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15032
  92. Jan 2020
  93. elifesciences.org elifesciences.org
    Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease
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    elifesciences.org/articles/49882
  94. www.sciencedirect.com www.sciencedirect.com
    Enhanced mGlu5 Signaling in Excitatory Neurons Promotes Rapid Antidepressant Effects via AMPA Receptor Activation
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