810 Matching Annotations
  1. Dec 2021
  2. www.nature.com www.nature.com
    A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis
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    nature.com/articles/s41467-021-27452-9
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    Synergy of epidermal growth factor (EGFR) and angiotensin II (AT1R) receptor determines composition and temporal pattern of transcriptome variation
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    link.springer.com/article/10.1007/s00018-021-04065-5
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    Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K
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    ncbi.nlm.nih.gov/pmc/articles/PMC8668188/
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    GFAT2 mediates cardiac hypertrophy through HBP-O-GlcNAcylation-Akt pathway
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    sciencedirect.com/science/article/pii/S2589004221014887
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    In vivo efficacy of tesevatinib in patient-derived xenograft glioblastoma models may be limited by tissue binding and compensatory signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC8172524/
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    Galectin-9 mediates neutrophil capture and adhesion in a CD44 and β2 integrin-dependent manner
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202100832R
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    Lysophosphatidic acid shifts metabolic and transcriptional landscapes to induce a distinct cellular state in human pluripotent stem cells
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    reader.elsevier.com/reader/sd/pii/S2211124721015497
  9. Nov 2021
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    Deciphering cell signaling networks with massively multiplexed biosensor barcoding
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    sciencedirect.com/science/article/pii/S0092867421013209
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    Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly
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    ncbi.nlm.nih.gov/pmc/articles/PMC8598234/
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    CNOT6/6L-mediated mRNA degradation in ovarian granulosa cells is a key mechanism of gonadotropin-triggered follicle development
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    sciencedirect.com/science/article/pii/S2211124721014856
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    AXL cooperates with EGFR to mediate neutrophil elastase-induced migration of prostate cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8567381/
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    Carbon dioxide inhibits COVID-19-type proinflammatory responses through extracellular signal-regulated kinases 1 and 2, novel carbon dioxide sensors
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    link.springer.com/article/10.1007/s00018-021-04005-3
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    RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC8550759/
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    TGF-β orchestrates the phenotype and function of monocytic myeloid-derived suppressor cells in colorectal cancer
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    link.springer.com/article/10.1007/s00262-021-03081-5
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    Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitors
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    Inhibition of Arabidopsis stomatal development by plastoquinone oxidation
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    sciencedirect.com/science/article/pii/S096098222101407X
  20. Oct 2021
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    Interleukin 6 reduces vascular smooth muscle cell apoptosis via Prep1 and is associated with aging
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202100943R
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    Schlafen 11 expression in human acute leukemia cells with gain-of-function mutations in the interferon-JAK signaling pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC8517841/
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    Deiodinase-3 is a thyrostat to regulate podocyte homeostasis
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    Sexual Experience Induces the Expression of Gastrin-Releasing Peptide and Oxytocin Receptors in the Spinal Ejaculation Generator in Rats
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    ncbi.nlm.nih.gov/pmc/articles/PMC8508609/
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    ASIC1a is required for neuronal activation via low-intensity ultrasound stimulation in mouse brain
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    ncbi.nlm.nih.gov/pmc/articles/PMC8510583/
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    Costimulation molecules differentially regulate the ERK-Zfp831 axis to shape T follicular helper cell differentiation
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    Promyelocytic leukemia protein targets MK2 to promote cytotoxicity
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    CWI pathway participated in vegetative growth and pathogenicity through a downstream effector AflRlm1 in Aspergillus flavus
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    ULK1 phosphorylation of striatin activates protein phosphatase 2A and autophagy
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  30. Sep 2021
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    Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity
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    Noncanonical mono(ADP-ribosyl)ation of zinc finger SZF proteins counteracts ubiquitination for protein homeostasis in plant immunity
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    Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors
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    Dopaminergic co-transmission with sonic hedgehog inhibits abnormal involuntary movements in models of Parkinson’s disease and L-Dopa induced dyskinesia
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    nature.com/articles/s42003-021-02567-3
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    Oncogene-dependent sloppiness in mRNA translation
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  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Probing the effect of clustering on EphA2 receptor signaling efficiency by subcellular control of ligand-receptor mobility
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    ncbi.nlm.nih.gov/pmc/articles/PMC8397371/
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    Establishment and genetic characterization of cell lines derived from proliferating nasal polyps and sinonasal inverted papillomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC8384845/
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    UV-induced reduction in Polycomb repression promotes epidermal pigmentation
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  39. Aug 2021
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    Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors
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    NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1
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    Cdc42 is required for male germline niche development in mice
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    A synaptic locus for TrkB signaling underlying ketamine rapid antidepressant action
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    CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance
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    Male fertility in mice requires classical and nonclassical androgen signaling
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    Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis
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    Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis
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    NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells
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    GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK
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    Muscarinic receptor M3 contributes to intestinal stem cell maintenance via EphB/ephrin-B signaling
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    Selective activation of PFKL suppresses the phagocytic oxidative burst
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    Melatonin inhibits osteoclastogenesis and bone loss in ovariectomized mice by regulating PRMT1-mediated signaling
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    USP8 deubiquitinates the leptin receptor and is necessary for leptin-mediated synapse formation
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    Multi-omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency
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    Crosstalk control and limits of physiological c-Jun N-terminal kinase activity for cell viability and neurite stability in differentiated PC12 cells - ScienceDirect
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    MEK inhibition overcomes resistance to EphA2-targeted therapy in uterine cancer
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    Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion
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    Sex Differences in the Rapid Cell Signaling Mechanisms Underlying the Memory-Enhancing Effects of 17β-Estradiol
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    MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo
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    Desacyl Ghrelin Decreases Anxiety-like Behavior in Male Mice
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    Stimulus evoked ERK-dependent phosphorylation of activity-regulated cytoskeleton-associated protein (Arc) regulates its neuronal subcellular localization
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    Melanocortin Receptor 4 Signaling Regulates Vertebrate Limb Regeneration
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    Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis
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    Promoted Interaction of C/EBPα with Demethylated Cxcr3 Gene Promoter Contributes to Neuropathic Pain in Mice
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    Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress
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  81. Jul 2021
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    BRAF Splice Variant Resistance to RAF Inhibitor Requires Enhanced MEK Association
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    Regulation of the endosomal SNX27-retromer by OTULIN
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    KRAS activation in gastric adenocarcinoma stimulates epithelial-to-mesenchymal transition to cancer stem-like cells and promotes metastasis
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    Cilostazol inhibits hyperglucose-induced vascular smooth muscle cell dysfunction by modulating the RAGE/ERK/NF-κB signaling pathways
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    CDK12 drives breast tumor initiation and trastuzumab resistance via WNT and IRS1‐ErbB‐PI3K signaling
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    Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations
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    Selective androgen receptor modulator S42 suppresses prostate cancer cell proliferation
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    Multi-omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency
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    New Noonan syndrome model mice with RIT1 mutation exhibit cardiac hypertrophy and susceptibility to β-adrenergic stimulation-induced cardiac fibrosis
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