3,429 Matching Annotations
  1. Jun 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Calpains orchestrate secretion of annexin-containing microvesicles during membrane repair
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    pmc.ncbi.nlm.nih.gov/articles/PMC12083247/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Limiting cap-dependent translation increases 20S proteasomal degradation and protects the proteomic integrity in autophagy-deficient skeletal muscle
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    pmc.ncbi.nlm.nih.gov/articles/PMC12087647/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interferon-induced PARP14-mediated ADP-ribosylation in p62 bodies requires the ubiquitin-proteasome system
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    pmc.ncbi.nlm.nih.gov/articles/PMC12084362/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Thermostable lamprey variable lymphocyte receptor antibody for detection of Plasmodium falciparum histidine rich protein-2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12085579/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Luteolin targets MKK4 to attenuate particulate matter-induced MMP-1 and inflammation in human keratinocytes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12081746/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated analysis of molecular atlases unveils modules driving developmental cell subtype specification in the human cortex
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    pmc.ncbi.nlm.nih.gov/articles/PMC12081304/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    EndoMAP.v1 charts the structural landscape of human early endosome complexes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12222028/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR screen decodes SWI/SNF chromatin remodeling complex assembly
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    pmc.ncbi.nlm.nih.gov/articles/PMC12125367/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Efficient generation of germline chimeras in a non-rodent species using rabbit induced pluripotent stem cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12134177/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of CD98HC phosphorylation by ATM impairs antiporter trafficking and drives glutamate toxicity in Ataxia telangiectasia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12130354/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    De novo design of protein condensation inhibitors by targeting an allosteric site of cGAS
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    pmc.ncbi.nlm.nih.gov/articles/PMC12134298/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of tumor-intrinsic NAT10 enhances antitumor immunity by triggering type I interferon response via MYC/CDK2/DNMT1 pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12134272/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clustering of NLRP3 induced by membrane or protein scaffolds promotes inflammasome assembly
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    pmc.ncbi.nlm.nih.gov/articles/PMC12117088/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FXYD2 marks and regulates maturity of β cells via ion channel-mediated signal transduction
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    pmc.ncbi.nlm.nih.gov/articles/PMC12137567/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FOXA2 promotes metastatic competence in small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12106783/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Elucidating the genetic mechanisms governing cytosine base editing outcomes through CRISPRi screens
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    pmc.ncbi.nlm.nih.gov/articles/PMC12092667/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptional and epigenetic rewiring by the NUP98::KDM5A fusion oncoprotein directly activates CDK12
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    pmc.ncbi.nlm.nih.gov/articles/PMC12089343/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cell trajectory modulation: rapid microfluidic biophysical profiling of CAR T cell functional phenotypes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12098694/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA-binding proteins DND1 and NANOS3 cooperatively suppress the entry of germ cell lineage
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    pmc.ncbi.nlm.nih.gov/articles/PMC12102168/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrative multi-omics identifies AP-1 transcription factor as a targetable mediator of acquired osimertinib resistance in non-small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12104440/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol for in vivo CRISPR knockout screening of autophagy genes to identify breast cancer metastasis suppressors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12084073/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Newcastle disease virus induces degradation of folliculin to regulate host cell energy metabolism and facilitate viral replication
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    pmc.ncbi.nlm.nih.gov/articles/PMC12164175/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fighting RNA viruses with a gold nanoparticle Cas13d gene-editing armor
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    pmc.ncbi.nlm.nih.gov/articles/PMC12088821/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Gallium disrupts endoplasmic reticulum iron metabolism to induce lipid metabolic reprogramming in glioblastoma cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12136846/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neddylation as a target in PIK3CA-mutated head and neck cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12036330/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rational Design and Organoid‐Based Evaluation of a Cocktail CAR‐γδ T Cell Therapy for Heterogeneous Glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12097020/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NKX2‐5/LHX1 and UHRF1 Establishing a Positive Feedback Regulatory Circuitry Drives Esophageal Squamous Cell Carcinoma through Epigenetic Dysregulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12120717/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chemotherapy‐Mediated Induction of PD‐L1 via SEI1 Facilitates Myeloma Immune Evasion
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    pmc.ncbi.nlm.nih.gov/articles/PMC12097018/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Evolutionary and functional analyses reveal a role for the RHIM in tuning RIPK3 activity across vertebrates
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    pmc.ncbi.nlm.nih.gov/articles/PMC12119088/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Creation of Genetically Modified Adipocytes for Tissue Engineering: Creatine Kinase B Overexpression Leads to Stimulated Glucose Uptake and Mitochondrial Potential Growth, but Lowered Lipid Synthesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12113200/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD44 Marks Dormant Tumor Cells After HER2 Inhibition in Breast Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12112730/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Xenoline-polarized macrophages as a physiologically relevant in vitro model of tumor-associated macrophages in glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12083673/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pancreatic cancer-restricted cryptic antigens are targets for T cell recognition
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    pmc.ncbi.nlm.nih.gov/articles/PMC12163983/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CEACAM1 as a mediator of B-cell receptor signaling in mantle cell lymphoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12120064/
  36. 52.53.155.43 52.53.155.43
    Roles for the long non-coding RNA Pax6os1/PAX6-AS1 in pancreatic beta cell function
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    52.53.155.43/bb3fc3d48d1d1a3ea4bd88205a0b31e5070fc2a9/PDF-html.html
  37. link.springer.com link.springer.com
    Differentiation of Brain Mural Cells from Human Pluripotent Stem Cell-Derived Neural Crest by Activation of Notch3 Signaling
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    link.springer.com/protocol/10.1007/978-1-0716-4474-4_2
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Disruption of ATR Signaling by Epstein–Barr Virus Latent Membrane Protein 1 Sensitizes Nasopharyngeal Carcinoma Cells to Cisplatin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12100692/
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The tau isoform 1N4R confers vulnerability of MAPT knockout human iPSC‐derived neurons to amyloid beta and phosphorylated tau‐induced neuronal dysfunction
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    pmc.ncbi.nlm.nih.gov/articles/PMC12089071/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Live Cell Imaging‐Compatible Bioreactor for the Interrogation of Cellular Responses to Modulated Flow Conditions
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    pmc.ncbi.nlm.nih.gov/articles/PMC12165081/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Icaritin Represses Autophagy to Promote Colorectal Cancer Cell Apoptosis and Sensitized Low‐Temperature Photothermal Therapy via Targeting HSP90‐TXNDC9 Interactions
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    pmc.ncbi.nlm.nih.gov/articles/PMC12120733/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Delivery of A Chemically Modified Noncoding RNA Domain Improves Dystrophic Myotube Function
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    pmc.ncbi.nlm.nih.gov/articles/PMC12120708/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Engineering novel CRISPRi repressors for highly efficient mammalian gene regulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12164210/
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deciphering the Transcription Factor Landscape in Prostate Cancer Progression: A Novel Approach to Understand NE Transdifferentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12120771/
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lovastatin Targets the USP14–Survivin Axis to Suppress Triple-Negative Breast Cancer via Ubiquitin-Mediated Proteasomal Degradation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12154129/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphorylation-induced SUMOylation promotes Ulk4 condensation at the ciliary tip to transduce Hedgehog signal
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    pmc.ncbi.nlm.nih.gov/articles/PMC12148026/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PELI2 inhibits colorectal cancer development through MAPK signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12160117/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Delta-catenin is required for cell proliferation in virus-positive Merkel cell carcinoma cell lines but not in human fibroblasts
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    pmc.ncbi.nlm.nih.gov/articles/PMC12153310/
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FEBS Press
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    pmc.ncbi.nlm.nih.gov/articles/PMC12138165/
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CCDC50 mediates the clearance of protein aggregates to prevent cellular proteotoxicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11572255/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Discovery of potential small molecule inhibitors against β-hCG: an in silico study with in vitro validation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12150210/
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuronal aging causes mislocalization of splicing proteins and unchecked cellular stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC12148940/
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12158785/
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    β-propeller protein-associated neurodegeneration protein WDR45 regulates stress granule disassembly via phase separation with Caprin-1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12141619/
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SWI/SNF ATPase silenced HLF potentiates lung metastasis in solid cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC12141477/
  56. www.sciencedirect.com www.sciencedirect.com
    Combined inhibition of KAT6A/B and Menin reverses estrogen receptor-driven gene expression programs in breast cancer
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    sciencedirect.com/science/article/pii/S2666379125002654
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Co-targeting BMI1 and MYC to eliminate cancer stem cells in squamous cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12147845/
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GLI2-HRD1 axis facilitates 5-FU resistance in gastric cancer cells by regulating ubiquitination degradation of UCK2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12159939/
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRAMP1-dependent histone H1 biogenesis is essential for topoisomerase II inhibitor tolerance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12240685/
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hepatic ChREBP reciprocally modulates systemic insulin sensitivity in NAFLD
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    pmc.ncbi.nlm.nih.gov/articles/PMC12155594/
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NUDT16 enhances the resistance of cancer cells to DNA-damaging agents by regulating replication fork stability via reversing HMGA1 ADP-ribosylation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12151214/
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    SLIRP amplifies antiviral signaling via positive feedback regulation and contributes to autoimmune diseases
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    sciencedirect.com/science/article/pii/S2211124725003596
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fusogenic Nanoreactor‐Based Detection of Extracellular Vesicle‐derived miRNAs for Diagnosing Atherosclerosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12160682/
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The ubiquitin ligase HUWE1 enhances WNT signaling by antagonizing destruction complex-mediated β-catenin degradation and through a mechanism independent of changes in β-catenin abundance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12148233/
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    Control of epithelial tissue organization by mRNA localization
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    pmc.ncbi.nlm.nih.gov/articles/PMC12141530/
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    Protocol for genetic dissection of class switch recombination using genome-editing tools
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    sciencedirect.com/science/article/pii/S2666166725002886
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    Vault RNAs aid RNA virus infection by facilitating cytoplasmic localization of hnRNP C and ELAVL1
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    sciencedirect.com/science/article/pii/S2211124725005947
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    Stromal Hedgehog Signaling Is Associated with Favorable Outcomes in Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12154493/
  69. www.cell.com www.cell.com
    The integrated stress response fine-tunes stem cell fate decisions upon serine deprivation and tissue injury
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    cell.com/cell-metabolism/fulltext/S1550-4131(25)00266-9
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    The RNA-stability-independent role of the RNA m6A reader YTHDF2 in promoting protein translation to confer tumor chemotherapy resistance
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    sciencedirect.com/science/article/pii/S109727652500454X
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    Regulation of Rho guanine nucleotide exchange factor 3 by phosphorylation in the PH domain
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    sciencedirect.com/science/article/pii/S2589004225010144
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR/Cas9 Screening Highlights PFKFB3 Gene as a Major Contributor to 5-Fluorouracil Resistance in Esophageal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12109790/
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    Glucose-1-phosphate promotes compartmentalization of glycogen with the pentose phosphate pathway in CD8+ memory T cells
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    sciencedirect.com/science/article/pii/S1097276525004587
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    Structures of butyrophilin multimers reveal a plier-like mechanism for Vγ9Vδ2 T cell receptor activation
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    sciencedirect.com/science/article/pii/S1074761325002328
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    RNA m6A dynamics promote transcription and RNA stability of bivalent genes during iPSC-induced generation of human lung progenitors
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    sciencedirect.com/science/article/pii/S221112472500573X
  76. 52.53.155.43 52.53.155.43
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  77. www.cell.com www.cell.com
    Pro-ferroptotic lipids as key control points for caveola formation and disassembly
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    cell.com/cell-reports/fulltext/S2211-1247(25)00560-1
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anti-CD45 PBD-based antibody-drug conjugates are effective targeted conditioning agents for gene therapy and stem cell transplant
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    pmc.ncbi.nlm.nih.gov/articles/PMC11184310/
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    Synaptic activity causes minute-scale changes in BAF complex composition and function
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    sciencedirect.com/science/article/pii/S1097276525004563
  80. 52.53.155.43 52.53.155.43
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  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fitness and transcriptional plasticity of human breast cancer single-cell-derived clones
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    pmc.ncbi.nlm.nih.gov/articles/PMC12117018/
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    Screening a living biobank identifies cabazitaxel as a strategy to combat acquired taxol resistance in high-grade serous ovarian cancer
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    sciencedirect.com/science/article/pii/S2666379125002332
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    Targeting IDH2 promotes antitumor immunity through epigenetic activation of cGAS-STING pathway
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    sciencedirect.com/science/article/pii/S0169500225005033
  85. May 2025
  86. www.sciencedirect.com www.sciencedirect.com
    Coiled-coil-domain-mediated TRIM E3 protein condensation modulates enzymatic activity and functional specificity
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    Hyperactivation of RAB5 disrupts the endosomal Rab cascade leading to endolysosomal dysregulation in Down syndrome: A necessary role for increased APP gene dose
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