4,692 Matching Annotations
  1. May 2026
  2. www.sciencedirect.com www.sciencedirect.com
    Taxane chemotherapy promotes response to TIM-3 checkpoint blockade via STING-mediated ER stress and HMGB1 secretion
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    sciencedirect.com/science/article/pii/S2666379126002053
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TENT5A Maintains MYC mRNA Stability to Enhance Osteosarcoma Stemness
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    pmc.ncbi.nlm.nih.gov/articles/PMC13136882/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Subcellular Redistribution of Endomembrane GPR15 Promotes NAD+-Mediated Metabolic Reprogramming and Boosts 5-FU Chemosensitivity in Colorectal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13136880/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TAK1 is a key regulator of oncogenic signaling and differentiation blockade in rhabdomyosarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13136027/
  6. aacrjournals.org aacrjournals.org
    Intra-tumoral tertiary lymphoid structures characterized by a B cell-related signature elicit antitumor effect through HAPLN3 in hepatocellular carcinoma
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    aacrjournals.org/cancerimmunolres/article/14/5/771/784463/Intratumoral-Tertiary-Lymphoid-Structures
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol for identifying cellular reprogramming minimal networks using combinatorial transcription factor screening
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    pmc.ncbi.nlm.nih.gov/articles/PMC13138051/
  8. www.biorxiv.org www.biorxiv.org
    Structure of zebrafish NLRP3 reveals a novel mode of inflammasome activation
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    biorxiv.org/content/10.64898/2026.04.17.719140v1
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    Systematic design of combination therapy by targeting master regulators of coexisting diffuse midline glioma cell states
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    nature.com/articles/s41588-026-02550-w
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    The cytotoxic effect of prexasertib is a consequence of dual inhibition on both CHK1 and AMPK
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    sciencedirect.com/science/article/pii/S2451945626001121
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    BAG6 and RNF126 promote the degradation of cytosolic misfolded proteins that contain buried degron motifs
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    biorxiv.org/content/10.64898/2026.04.24.720685v1
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    An RNA-centric interactomics screen identifies novel proviral and antiviral genome binding interactors for tick-borne encephalitis virus
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    biorxiv.org/content/10.64898/2026.04.23.720161v1
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The interferon-stimulated gene product HERC5 inhibits human LINE-1 retrotransposition with an ISGylation-independent mechanism
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    pmc.ncbi.nlm.nih.gov/articles/PMC13128273/
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    The circadian gene Dec2 promotes pancreatic cancer progression and dormancy through immune evasion
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    sciencedirect.com/science/article/pii/S1534580726001243
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Incorporation of genome-bound cellular proteins into HIV-1 particles regulates viral infection
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    pmc.ncbi.nlm.nih.gov/articles/PMC13124994/
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    Time-resolved proteomics reveals five modules of stress granule disassembly and identifies SYNCRIP as a late-phase clearance factor
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    sciencedirect.com/science/article/pii/S1357272526000658
  17. Apr 2026
  18. www.science.org www.science.org
    MYC-bound enhancer RNAs in cis regulate gene transcription and tumorigenesis
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    science.org/doi/10.1126/sciadv.aeb5147
  19. dx.doi.org dx.doi.org
    A supracellular actin network transmits forces over long distances at the apical surface of squamous carcinoma cells
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    dx.doi.org/10.1242/jcs.264424
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HCMV infection depends on EGLN1-mediated mitochondrial activation to increase dNTP pools for viral DNA replication
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    pmc.ncbi.nlm.nih.gov/articles/PMC13200821/
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    Unbiased niche labeling maps immune-excluded niche in bone metastasis
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    sciencedirect.com/science/article/pii/S0092867426003983
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interaction of NDRG1 and TGM2 modulates DNA replication and repair
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    pmc.ncbi.nlm.nih.gov/articles/PMC13112271/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Distinct malignant cell states and myeloid glutamate signaling associated with aggressive pancreatic neuroendocrine tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC13118131/
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    Krüppel-like factor 2 programs early exhausted T cell states and restrains antiviral immunity
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    sciencedirect.com/science/article/pii/S1074761326001408
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    USP15 stabilizes c-Myc to drive sunitinib resistance by suppressing cuproptosis in clear cell renal cell carcinoma
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    sciencedirect.com/science/article/pii/S2211124726004067
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    GLIS3 marks a neural-like progenitor cell state that drives metastasis in pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S221112472600392X
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated Multi-omic Profiling Identifies BRD8/EP400 as a Pivotal Chromatin Module Mediating Anti-HER2 Response in HR+/HER2+ Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13110125/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Prion propagation is controlled by a hierarchical network involving the nuclear Tfap2c and hnRNP K factors and the cytosolic mTORC1 complex
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    pmc.ncbi.nlm.nih.gov/articles/PMC13108870/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Actomyosin contractility is a potent suppressor of mesoderm induction by human pluripotent stem cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13108843/
  30. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    CCDC80 suppresses high-grade serous ovarian cancer migration via negative regulation of B7-H3
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70235
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PALINCODE: Recording cell lineage with ternary palindromic CRISPR bits
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    pmc.ncbi.nlm.nih.gov/articles/PMC13105057/
  32. www.mdpi.com www.mdpi.com
    Dual Specificity Phosphatase 4 Enhances Immunotherapy Response by Inhibiting TGF-β1 Secretion in Hepatocellular Carcinoma
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    mdpi.com/2072-6694/18/8/1289
  33. www.cell.com www.cell.com
    Tuning the sensitivity of mechanosensory receptors through histidine scanning
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    cell.com/cell/fulltext/S0092-8674(25)01499-0
  34. www.biorxiv.org www.biorxiv.org
    Sacituzumab Govitecan as an Effective Strategy for Sensitizing Chemoresistant HNSCC Cells to Senolytic Intervention
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    biorxiv.org/content/10.64898/2026.04.13.718209v1
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol for enhancing CRISPR-Cas9 genome editing using histone deacetylase inhibition and engineered virus-like particle delivery
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    pmc.ncbi.nlm.nih.gov/articles/PMC13122305/
  36. aacrjournals.org aacrjournals.org
    Immunotherapy Inhibits Tumor Cholesterol Synthesis via the IFN-γ-ΙRF1-SREBF2 Axis
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    aacrjournals.org/cancerimmunolres/article/14/3/478/774853/Immunotherapy-Inhibits-Tumor-Cholesterol-Synthesis
  37. aacrjournals.org aacrjournals.org
    Bone Metastatic Progression of Prostate Cancer is Regulated by TRIM28-LDHA Mediated Metabolism
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    aacrjournals.org/mcr/article/24/2/93/772003/Bone-Metastatic-Progression-of-Prostate-Cancer-Is
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    Systematic discovery of pro- and anti-HIV host factors in primary human CD4+ T cells
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    sciencedirect.com/science/article/pii/S009286742600382X
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    ID2 suppresses multiple myeloma cell proliferation by repressing the activity of the transcription factor TCF3
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    aacrjournals.org/bloodcancerdiscov/article/7/1/129/771360/ID2-Suppresses-Multiple-Myeloma-Cell-Proliferation
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    Functional genetic screens reveal key pathways instructing the molecular phenotypes of tumor-associated macrophages
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    aacrjournals.org/cancerimmunolres/article/13/12/2054/768330/Functional-Genetic-Screens-Reveal-Key-Pathways
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    Chronic ISG15 Exposure Accelerates CD8+ T-cell Dysfunction while Increasing PD-1 Blockade Sensitivity in Oral Squamous Cell Carcinoma
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    aacrjournals.org/cancerimmunolres/article/13/11/1829/766805/Chronic-ISG15-Exposure-Accelerates-CD8-T-cell
  42. aacrjournals.org aacrjournals.org
    MTHFD2-mediated ubiquitination and degradation of FOXO1 promote tongue squamous cell carcinoma progression
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    aacrjournals.org/mcr/article/24/4/270/775482/MTHFD2-Mediated-Ubiquitination-and-Degradation-of
  43. www.nature.com www.nature.com
    Table 2 Overview of plasmids used.
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    nature.com/articles/s41598-026-48584-2/tables/2
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RHOV is a Detachment-Responsive Rho GTPase Necessary for Ovarian Cancer Peritoneal Metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13089303/
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechanisms of gene regulation by SRCAP and H2A.Z
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    pmc.ncbi.nlm.nih.gov/articles/PMC13087030/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The WNK-OXSR1 osmosensing pathway mediates intestinal regeneration via Hippo-YAP signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13083915/
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    An autochthonous CRISPR activation screening platform for characterizing tissue-specific oncogene selection
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    sciencedirect.com/science/article/pii/S266637912600176X
  48. www.biorxiv.org www.biorxiv.org
    Advanced models of lobular breast cancer metastasis capture clinical organ tropism, endocrine response, and bone remodeling
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    biorxiv.org/content/10.64898/2026.03.13.711653v1
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of USP7 destabilizes the noncanonical PRC1.1 complex and induces neuroblastoma differentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13082235/
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    mTORC1 activity suppresses ferroptosis through a SCARB1-dependent HDL-tocopherol uptake pathway
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    sciencedirect.com/science/article/pii/S1097276526001954
  51. www.cell.com www.cell.com
    The Erlin1/2 complex is a dynamic scaffold for membrane microdomain assembly on the endoplasmic reticulum
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    cell.com/molecular-cell/abstract/S1097-2765(26)00157-7
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Adapting Upright Light Sheet Fluorescence Microscopy for Imaging at Air-Liquid Interface
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    pmc.ncbi.nlm.nih.gov/articles/PMC13082110/
  53. www.biorxiv.org www.biorxiv.org
    Transcription Factor Subtype Governs Response and Resistance to DLL3-Directed T-Cell Engagement in Small Cell Lung Cancer
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    biorxiv.org/content/10.64898/2026.04.02.715020v1
  54. 54.241.53.176 54.241.53.176
    2026.04.04.716465.full-html.html
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    eIF4G2-dependent translation restrains pancreatic cancer progression
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    biorxiv.org/content/10.64898/2026.03.14.711799v1
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A hormetic transcriptional program coregulates invasion, proliferation and dormancy to define metastatic potential
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    pmc.ncbi.nlm.nih.gov/articles/PMC13077004/
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    Human immune aging clock identifies RUNX1 as a decelerator of T cell senescence
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    sciencedirect.com/science/article/pii/S1074761326000774
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    AMBRA1 enhances Sonic Hedgehog signaling during cerebellar development and in medulloblastoma
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    sciencedirect.com/science/article/pii/S1534580726001206
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A hotspot phosphorylation site on SHP2 drives oncoprotein activation and drug resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC13066003/
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genetically encoded manipulation of ATP/ADP ratio in human cells uncovers proteomic and physiological signatures of energy stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC13159532/
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    Activation of neurogenesis improves amyloid-β pathology and cognitive function through AMP kinase signaling in Alzheimer’s disease model mice
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    sciencedirect.com/science/article/pii/S2211124726003281
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of STMN1 as a lactylation-related driver of lung cancer progression using Mendelian randomization
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    pmc.ncbi.nlm.nih.gov/articles/PMC13051255/
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Laptm4a mediates renal ischemia-reperfusion injury by regulating the UNC5B-AKT/mTOR signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC13053316/
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cholecystokinin A Receptor Knockdown Diminishes Colon Cancer Cell Invasive Potential via Modulation of Integrin/FAK, EMT, and uPA/uPAR/MMP2 Axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13040287/
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ONX-0914 Suppresses Hormone-Sensitive Prostate Cancer by Promoting O-GlcNAcylation-Mediated Stabilization of TCF7L1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13040289/
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    APOBEC3B regulates HPV replication by inducing R-loop formation and DNA damage
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    pmc.ncbi.nlm.nih.gov/articles/PMC13035229/
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD4 T-cell platform for delivering interferons as an antiviral countermeasure with a focus on SARS-CoV-2
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    pmc.ncbi.nlm.nih.gov/articles/PMC13032555/
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Human NLRP3 inflammasome activation leads to formation of condensate at the microtubule organizing center
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    pmc.ncbi.nlm.nih.gov/articles/PMC13025127/
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SLC13A2-transported citrate remodels transcriptional regulation through protein acetylation to suppress tumor growth
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    pmc.ncbi.nlm.nih.gov/articles/PMC13060607/
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chromatin architecture reprogramming reveals novel epigenetic dependencies in breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12849445/
  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Investigating PKD2 deficiency-associated cardiomyopathies using hESC-cardiomyocytes and bioengineered 3D ventricular cardiac tissue strips
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    pmc.ncbi.nlm.nih.gov/articles/PMC13039962/
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol to identify SINE-VNTR-Alu regulators using genome-wide screening in human K562 cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13058971/
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PTEN Loss Promotes PI3Kβ Phosphorylation and EPHA2/SRC/p-PI3KβY962 Complex Assembly to Drive Tumorigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13056290/
  74. www.nature.com www.nature.com
    X-linked cancer-associated polypeptide (XCP) from lncRNA1456 modulates PHF8 histone demethylase activity to regulate the epigenome, gene expression, and cellular pathways in breast cancer
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    nature.com/articles/s41388-026-03740-w
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    Host microRNA-31-5p regulates KHDRBS3 expression and modulates viral gene expression during KSHV lytic reactivation
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    sciencedirect.com/science/article/pii/S221112472600238X
  76. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of the mitochondria-related gene IRF7 shared by physical exercise and Parkinson’s disease and exploration of its potential molecular mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC13033288/
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An epigenetic bifunctional that toggles between transactivation and repression
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    pmc.ncbi.nlm.nih.gov/articles/PMC13015318/
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapeutic scheduling of WEE1 inhibition preserves T cell function and promotes immune control of HPV+ tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC13015432/
  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Reprogramming mRNA localization by targeted RNA-protein interference
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    pmc.ncbi.nlm.nih.gov/articles/PMC12991119/
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Depleting HIF-1α attenuates the progression of osteosarcoma, but tumorigenicity is sustained through HIF-independent pathways
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    pmc.ncbi.nlm.nih.gov/articles/PMC13007490/
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    circOMA1 delivered by exosomes regulates DRD2-mediated prolactinoma resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC13042270/
  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Microbial sensing through the non-canonical inflammasome modulates airway type 2 immunity
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    pmc.ncbi.nlm.nih.gov/articles/PMC13033652/
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CENPF Overexpression Induced by HBV Infection Facilitates the G1/S Cell Cycle Transition of Hepatocellular Carcinoma Cells via MYC Pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC13051194/
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    COG5 deficiency disrupts cellular copper homeostasis and underlies the impaired mitochondrial OXPHOS function
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    pmc.ncbi.nlm.nih.gov/articles/PMC12987470/
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Allele-selective disruption of pathogenic VWF variants in type 2 von Willebrand disease using CRISPR/Cas9
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    pmc.ncbi.nlm.nih.gov/articles/PMC12952769/
  86. aacrjournals.org aacrjournals.org
    Serotonin modulates lineage plasticity in neuroendocrine prostate cancer via epigenetic reprogramming
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