473 Matching Annotations
  1. Feb 2021
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Srsf10 and the minor spliceosome control tissue-specific and dynamic SR protein expression
    1
    1. scibot 25 Feb 2021
      RRID:Addgene_62988

      DOI: 10.7554/eLife.56075

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    ncbi.nlm.nih.gov/pmc/articles/PMC7244321/
  3. elifesciences.org elifesciences.org
    The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1
    1
    1. scibot 25 Feb 2021
      Addgene_62988

      DOI: 10.7554/eLife.40009

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    elifesciences.org/articles/40009
  4. www.cell.com www.cell.com
    RIPK1 Promotes Energy Sensing by the mTORC1 Pathway
    1
    1. scibot 25 Feb 2021
      RRID:Addgene_62988

      DOI: 10.1016/j.molcel.2020.11.008

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      Curator: @Naa003

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      RRIDCUR:Validated RRID:Addgene_62988
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    cell.com/molecular-cell/abstract/S1097-2765(20)30786-3
  5. www.sciencedirect.com www.sciencedirect.com
    OTUB1 Is a Key Regulator of RIG-I-Dependent Immune Signaling and Is Targeted for Proteasomal Degradation by Influenza A NS1
    1
    1. scibot 24 Feb 2021
      plasmid_62988

      DOI: 10.1016/j.celrep.2020.01.015

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      RRID:Addgene_62988
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    sciencedirect.com/science/article/pii/S2211124720300243
  6. www.nature.com www.nature.com
    Generation of myostatin edited horse embryos using CRISPR/Cas9 technology and somatic cell nuclear transfer
    1
    1. scibot 24 Feb 2021
      plasmid_62

      DOI: 10.1038/s41598-020-72040-4

      Resource: RRID:Addgene_62988

      Curator: @evieth

      SciCrunch record: RRID:Addgene_62988

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      RRID:Addgene_62988 RRIDCUR:Unresolved RRIDCUR:NotRRID
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    nature.com/articles/s41598-020-72040-4
  7. link.springer.com link.springer.com
    The inflammatory kinase IKKα phosphorylates and stabilizes c-Myc and enhances its activity
    1
    1. scibot 24 Feb 2021
      RRID:Addgene_62

      DOI: 10.1186/s12943-021-01308-8

      Resource: RRID:Addgene_62988

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_62988

      Curator comments: pSpCas9(BB)-2A-Puro (PX459) V2.0

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      RRID:Addgene_62988 RRIDCUR:Unresolved RRIDCUR:SyntaxError
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    link.springer.com/article/10.1186/s12943-021-01308-8
  8. www.frontiersin.org www.frontiersin.org
    Regulation of the Transferrin Receptor Recycling in Hepatitis C Virus-Replicating Cells
    1
    1. scibot 24 Feb 2021
      plasmid_629881

      DOI: 10.3389/fcell.2020.00044

      Resource: RRID:Addgene_62988

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_62988

      Curator comments: pSpCas9(BB)-2A-Puro (PX459) V2.0

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      RRID:Addgene_62988 RRIDCUR:Unresolved RRIDCUR:SyntaxError
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    frontiersin.org/article/10.3389/fcell.2020.00044/full
  9. www.sciencedirect.com www.sciencedirect.com
    Generation of iPSC line from MYH7 R403L mutation carrier with severe hypertrophic cardiomyopathy and isogenic CRISPR/Cas9 corrected control
    1
    1. scibot 12 Feb 2021
      Addgene_62988

      DOI: 10.1016/j.scr.2021.102245

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      RRID:Addgene_62988 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S187350612100091X
  10. www.sciencedirect.com www.sciencedirect.com
    Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis
    1
    1. scibot 01 Feb 2021
      RRID:Addgene_62988

      DOI: 10.1016/j.cell.2020.11.012

      Resource: RRID:Addgene_62988

      Curator: @bandrow

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      RRID:Addgene_62988 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867420315294
  11. Jan 2021
  12. www.sciencedirect.com www.sciencedirect.com
    DCAF14 promotes stalled fork stability to maintain genome integrity
    1
    1. scibot 28 Jan 2021
      Addgene Cat#62988

      DOI: 10.1016/j.celrep.2020.108669

      Resource: RRID:Addgene_62988

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_62988

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      RRIDCUR:Missing RRID:Addgene_62988
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    sciencedirect.com/science/article/pii/S2211124720316582
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling
    1
    1. scibot 26 Jan 2021
      RRID:Addgene_62988

      DOI: 10.1016/j.cell.2020.12.024

      Resource: RRID:Addgene_62988

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      RRIDCUR:Validated RRID:Addgene_62988
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    ncbi.nlm.nih.gov/pmc/articles/PMC7868890/
  14. www.sciencedirect.com www.sciencedirect.com
    Multi-scale Dynamical Modeling of T Cell Development from an Early Thymic Progenitor State to Lineage Commitment
    1
    1. scibot 22 Jan 2021
      Addgene_62988

      DOI: 10.1016/j.celrep.2020.108622

      Resource: RRID:Addgene_62988

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      RRID:Addgene_62988 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124720316119
  15. link.springer.com link.springer.com
    The inflammatory kinase IKKα phosphorylates and stabilizes c-Myc and enhances its activity
    1
    1. scibot 21 Jan 2021
      plasmid_62988

      DOI: 10.1186/s12943-021-01308-8

      Resource: RRID:Addgene_62988

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_62988

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      RRID:Addgene_62988 RRIDCUR:Validated
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    link.springer.com/article/10.1186/s12943-021-01308-8
  16. www.sciencedirect.com www.sciencedirect.com
    Impact of WIN site inhibitor on the WDR5 interactome
    1
    1. scibot 20 Jan 2021
      Addgene_62988

      DOI: 10.1016/j.celrep.2020.108636

      Resource: RRID:Addgene_62988

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_62988

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      RRIDCUR:Validated RRID:Addgene_62988
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    sciencedirect.com/science/article/pii/S2211124720316259
  17. www.sciencedirect.com www.sciencedirect.com
    The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway
    1
    1. scibot 20 Jan 2021
      Addgene_62988

      DOI: 10.1016/j.celrep.2020.108659

      Resource: RRID:Addgene_62988

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_62988

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      RRIDCUR:Validated RRID:Addgene_62988
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    sciencedirect.com/science/article/pii/S221112472031648X
  18. www.sciencedirect.com www.sciencedirect.com
    MAU2 and NIPBL Variants Impair the Heterodimerization of the Cohesin Loader Subunits and Cause Cornelia de Lange Syndrome
    1
    1. scibot 15 Jan 2021
      Addgene_62988

      DOI: 10.1016/j.celrep.2020.107647

      Resource: RRID:Addgene_62988

      Curator: @ethanbadger

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      RRID:Addgene_62988 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124720306008
  19. www.sciencedirect.com www.sciencedirect.com
    A Molecular Mechanism for Turning Off IRE1α Signaling during Endoplasmic Reticulum Stress
    1
    1. scibot 05 Jan 2021
      pSpCas9(BB)-2A-Puro

      DOI: 10.1016/j.celrep.2020.108563

      Resource: RRID:Addgene_62988

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_62988

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      RRID:Addgene_62988 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S2211124720315527
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conformation of the nuclear pore in living cells is modulated by transport state
    1
    1. scibot 05 Jan 2021
      Addgene_62988

      DOI: 10.7554/eLife.60654

      Resource: RRID:Addgene_62988

      Curator: @evieth

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      RRID:Addgene_62988 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC7752133/
  21. Dec 2020
  22. www.sciencedirect.com www.sciencedirect.com
    Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch
    1
    1. scibot 30 Dec 2020
      Addgene_62988

      DOI: 10.1016/j.celrep.2020.108529

      Resource: RRID:Addgene_62988

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_62988

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      RRIDCUR:Validated RRID:Addgene_62988
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    sciencedirect.com/science/article/pii/S2211124720315187
  23. www.sciencedirect.com www.sciencedirect.com
    Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions
    1
    1. scibot 17 Dec 2020
      PX459

      DOI: 10.1016/j.celrep.2020.108495

      Resource: RRID:Addgene_62988

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_62988

      Curator comments: pSpCas9(BB)-2A-Puro (PX459) V2.0

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      RRIDCUR:Missing RRID:Addgene_62988
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    sciencedirect.com/science/article/pii/S2211124720314844
  24. www.sciencedirect.com www.sciencedirect.com
    Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD
    1
    1. scibot 17 Dec 2020
      Addgene_62988

      DOI: 10.1016/j.molcel.2020.12.006

      Resource: RRID:Addgene_62988

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_62988

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      RRIDCUR:Validated RRID:Addgene_62988
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    sciencedirect.com/science/article/pii/S1097276520308984
  25. www.sciencedirect.com www.sciencedirect.com
    The Rigor and Transparency Index Quality Metric for Assessing Biological and Medical Science Methods
    1
    1. scibot 10 Dec 2020
      RRID:Addgene_62988

      DOI: 10.1016/j.isci.2020.101698

      Resource: RRID:Addgene_62988

      Curator: @Naa003

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      RRID:Addgene_62988 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2589004220308907
  26. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Testes of DAZL null neonatal sheep lack prospermatogonia but maintain normal somatic cell morphology and marker expression
    1
    1. scibot 08 Dec 2020
      RRID:Addgene_62988

      DOI: 10.1002/mrd.23443

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      RRIDCUR:Validated RRID:Addgene_62988
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    onlinelibrary.wiley.com/doi/10.1002/mrd.23443
  27. Nov 2020
  28. www.sciencedirect.com www.sciencedirect.com
    Generation of GADD45A gene knockout human embryonic stem cell line using CRISPR/Cas9
    1
    1. scibot 24 Nov 2020
      RRID:Addgene_62988

      DOI: 10.1016/j.scr.2020.102090

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      RRIDCUR:Validated RRID:Addgene_62988
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    sciencedirect.com/science/article/pii/S1873506120303913
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-adrenergic receptor signaling evokes the PKA-ASK axis in mature brown adipocytes
    1
    1. scibot 04 Nov 2020
      RRID:Addgene_62988

      DOI: 10.1371/journal.pone.0232645

      Resource: RRID:Addgene_62988

      Curator: @evieth

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      RRIDCUR:Validated RRID:Addgene_62988
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    ncbi.nlm.nih.gov/pmc/articles/PMC7591029/
  30. Oct 2020
  31. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Premature aging syndrome showing random chromosome number instabilities with CDC20 mutation
    1
    1. scibot 27 Oct 2020
      RRID:Addgene_62988

      DOI: 10.1111/acel.13251

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      Curator: @Naa003

      SciCrunch record: RRID:Addgene_62988

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      RRIDCUR:Validated RRID:Addgene_62988
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    pubmed.ncbi.nlm.nih.gov/33094908/
  32. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Temporal Proteomic Analysis of Herpes Simplex Virus 1 Infection Reveals Cell-Surface Remodeling via pUL56-Mediated GOPC Degradation
    1
    1. scibot 07 Oct 2020
      RRID:Addgene_62988

      DOI: 10.1016/j.celrep.2020.108235

      Resource: RRID:Addgene_62988

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      RRID:Addgene_62988 RRIDCUR:Validated
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    pubmed.ncbi.nlm.nih.gov/33027661/
  33. Sep 2020
  34. www.nature.com www.nature.com
    Generation of myostatin edited horse embryos using CRISPR/Cas9 technology and somatic cell nuclear transfer
    1
    1. scibot 30 Sep 2020
      RRID:Addgene_62988

      DOI: 10.1038/s41598-020-72040-4

      Resource: RRID:Addgene_62988

      Curator: @evieth

      SciCrunch record: RRID:Addgene_62988

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      RRID:Addgene_62988 RRIDCUR:Validated
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    nature.com/articles/s41598-020-72040-4
  35. www.sciencedirect.com www.sciencedirect.com
    CRISPR-Mediated Protein Tagging with Nanoluciferase to Investigate Native Chemokine Receptor Function and Conformational Changes
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_62988

      DOI: 10.1016/j.chembiol.2020.01.010

      Resource: RRID:Addgene_62988

      Curator: @ethanbadger

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      RRIDCUR:Validated RRID:Addgene_62988
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    sciencedirect.com/science/article/pii/S2451945620300350
  36. www.mdpi.com www.mdpi.com
    Evaluation of the CRISPR/Cas9 Genetic Constructs in Efficient Disruption of Porcine Genes for Xenotransplantation Purposes Along with an Assessment of the Off-Target Mutation Formation
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_62988

      DOI: 10.3390/genes11060713

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      Curator: @Naa003

      SciCrunch record: RRID:Addgene_62988

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      RRIDCUR:Validated RRID:Addgene_62988
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    mdpi.com/2073-4425/11/6/713
  37. link.springer.com link.springer.com
    Increased expression and retention of the secretory chaperone proSAAS following cell stress
    1
    1. scibot 26 Sep 2020
      plasmid_62988

      DOI: 10.1007/s12192-020-01128-7

      Resource: RRID:Addgene_62988

      Curator: @ethanbadger

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      RRIDCUR:Validated RRID:Addgene_62988
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    link.springer.com/article/10.1007/s12192-020-01128-7
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    hnRNPDL Phase Separation Is Regulated by Alternative Splicing and Disease-Causing Mutations Accelerate Its Aggregation
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_62988

      DOI: 10.1016/j.celrep.2019.12.080

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      Curator: @ethanbadger

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      RRIDCUR:Validated RRID:Addgene_62988
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    ncbi.nlm.nih.gov/pmc/articles/PMC6996132/
  39. www.sciencedirect.com www.sciencedirect.com
    Tandem Paired Nicking Promotes Precise Genome Editing with Scarce Interference by p53
    1
    1. scibot 23 Sep 2020
      RRID:Addgene_62988

      DOI: 10.1016/j.celrep.2019.12.064

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      Curator: @ethanbadger

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      RRID:Addgene_62988 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719317218
  40. www.sciencedirect.com www.sciencedirect.com
    The Alazami Syndrome-Associated Protein LARP7 Guides U6 Small Nuclear RNA Modification and Contributes to Splicing Robustness
    1
    1. scibot 23 Sep 2020
      plasmid_62988

      DOI: 10.1016/j.molcel.2020.01.001

      Resource: RRID:Addgene_62988

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      RRID:Addgene_62988 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276520300010
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures
    1
    1. scibot 17 Sep 2020
      RRID:Addgene_62988

      DOI: 10.1038/s41467-020-16212-w

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      Curator: @evieth

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      RRID:Addgene_62988 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC7224215/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BMAL1 coordinates energy metabolism and differentiation of pluripotent stem cells
    1
    1. scibot 16 Sep 2020
      plasmid_62988

      DOI: 10.26508/lsa.201900534

      Resource: RRID:Addgene_62988

      Curator: @evieth

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      RRIDCUR:Validated RRID:Addgene_62988
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    ncbi.nlm.nih.gov/pmc/articles/PMC7156282/
  43. www.mdpi.com www.mdpi.com
    Rhabdovirus Infection Is Dependent on Serine/Threonine Kinase AP2-Associated Kinase 1
    1
    1. scibot 16 Sep 2020
      RRID:Addgene_62988

      DOI: 10.3390/life10090170

      Resource: RRID:Addgene_62988

      Curator: @Naa003

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      RRIDCUR:Validated RRID:Addgene_62988
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    mdpi.com/2075-1729/10/9/170
  44. www.sciencedirect.com www.sciencedirect.com
    Atrx Deletion in Neurons Leads to Sexually Dimorphic Dysregulation of miR-137 and Spatial Learning and Memory Deficits
    1
    1. scibot 15 Sep 2020
      Addgene_62988

      DOI: 10.1016/j.celrep.2020.107838

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      RRID:Addgene_62988 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124720308196
  45. link.springer.com link.springer.com
    RBM45 associates with nuclear stress bodies and forms nuclear inclusions during chronic cellular stress and in neurodegenerative diseases
    1
    1. scibot 14 Sep 2020
      RRID:Addgene_62988

      DOI: 10.1186/s40478-020-00965-y

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      RRID:Addgene_62988 RRIDCUR:Validated
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    link.springer.com/article/10.1186/s40478-020-00965-y
  46. elifesciences.org elifesciences.org
    A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation
    1
    1. scibot 13 Sep 2020
      RRID:Addgene_62988

      DOI: 10.7554/eLife.58659

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      Curator: @evieth

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      RRIDCUR:Validated RRID:Addgene_62988
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    elifesciences.org/articles/58659
  47. link-springer-com.ezproxy.rice.edu link-springer-com.ezproxy.rice.edu
    FGF primes angioblast formation by inducing ETV2 and LMO2 via FGFR1/BRAF/MEK/ERK
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    Loss of TET2 Affects Proliferation and Drug Sensitivity through Altered Dynamics of Cell-State Transitions
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    Regulation of the Transferrin Receptor Recycling in Hepatitis C Virus-Replicating Cells
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    Regulation of poly(A)-specific ribonuclease activity by reversible lysine acetylation
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    The primary cilium and lipophagy translate mechanical forces to direct metabolic adaptation of kidney epithelial cells
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    All three mammalian MutL complexes are required for repeat expansion in a mouse cell model of the Fragile X-related disorders
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    Recognition of Semaphorin Proteins by P. sordellii Lethal Toxin Reveals Principles of Receptor Specificity in Clostridial Toxins
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    κB-Ras and Ral GTPases regulate acinar to ductal metaplasia during pancreatic adenocarcinoma development and pancreatitis
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    The polycomb group protein PCGF6 mediates germline gene silencing by recruiting histone-modifying proteins to target gene promoters
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    Generation of isogenic Propionyl-CoA Carboxylase Beta Subunit (PCCB) deficient induced pluripotent stem cell lines
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    Novel role for CRK adaptor proteins as essential components of SRC/FAK signaling for epithelial‐mesenchymal transition and colorectal cancer aggressiveness
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    NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency
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    G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules
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    Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression
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    The ATF3 Transcription Factor Is a Short-Lived Substrate of the Arg/N-Degron Pathway
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  62. Jan 2020
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    TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL
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    Double‐strand breakage in the extrachromosomal double minutes triggers their aggregation in the nucleus, micronucleation, and morphological transformation
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    Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72
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    Characterization of the activity, aggregation, and toxicity of heterodimers of WT and ALS-associated mutant Sod1
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    The protective effects of hydrogen sulfide on the myocardial ischemia via regulating Bmal1
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    Persistent epigenetic memory impedes rescue of the telomeric phenotype in human ICF iPSCs following DNMT3B correction
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    Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex
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    MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition
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    Mitochondrial One-Carbon Pathway Supports Cytosolic Folate Integrity in Cancer Cells
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    Activity of the SPCA1 Calcium Pump Couples Sphingomyelin Synthesis to Sorting of Secretory Proteins in the Trans-Golgi Network
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