2,087 Matching Annotations
  1. Oct 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting the ERα DBD-LBD interface with mitoxantrone disrupts receptor function through proteasomal degradation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12496009/
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    A cancer-specific antigen drives histone acetylation by stabilizing the acetyltransferases
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    sciencedirect.com/science/article/pii/S2211124725011799
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    A Nitroreductase-Activated Chemiluminescent Prodrug for Real-Time Monitoring of Camptothecin Release in Peritoneal Metastasis Theranostics
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    pubs.acs.org/doi/full/10.1021/acs.jmedchem.5c01674
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    Metal-Free Molecular Editing of Indole via Tandem Reaction: Access to 2-Aryl-3-aryldiazenylindole for Theranostic Applications
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    pmc.ncbi.nlm.nih.gov/articles/PMC12496193/
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    Spatially resolved in situ profiling of mRNA life cycle at transcriptome scale in intact cells and tissues using STARmap PLUS, RIBOmap and TEMPOmap
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    nature.com/articles/s41596-025-01248-3
  7. Sep 2025
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    Safe immunosuppression-resistant pan-cancer immunotherapeutics by velcro-like density-dependent targeting of tumor-associated carbohydrate antigens
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    sciencedirect.com/science/article/pii/S0092867425010323
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    Ubiquitination-activated TAB–TAK1–IKK–NF-κB axis modulates gene expression for cell survival in the lysosomal damage response
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    pmc.ncbi.nlm.nih.gov/articles/PMC12459955/
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    The nuclear pore complex connects energy sensing to transcriptional plasticity in longevity
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    Nipah virus matrix protein uses cortical actin to stabilize the virus assembly sites and promote budding
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    The kinesin motor Kif9 regulates centriolar satellite positioning during interphase
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    A smart gene circuit for precise regulation of tumor cell behavior
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    The type 1 diabetes candidate genes PTPN2 and BACH2 regulate the IFN-α-induced crosstalk between JAK/STAT and MAPKs pathways in human beta cells
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    Efficacy of precisely tailored phage cocktails targeting carbapenem-resistant Acinetobacter baumannii reveals evolutionary trade-offs: a proof-of-concept study
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    Mitochondrial proteostatic stress disrupts mitoribosome biogenesis and translation
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    c-Met inhibitor NVP-BVU972 induces antiviral protection and suppresses NF-κB-mediated inflammation
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    PPM1D is directly degraded by proteasomes in a ubiquitination-independent manner through its carboxyl-terminal region
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    A rapid imaging-based screen for induced-proximity degraders identifies a potent degrader of oncoprotein SKP2
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    Connexin 43 drives glioblastoma cancer stem cell phenotypes through a WNK lysine-deficient protein kinase 1-c-MYC signaling axis
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    The E3 ubiquitin ligase SIAH1 targets a bacterial pore-forming toxin to facilitate xenophagy
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    Targeting FSP1 to induce ferroptosis in chromophobe renal cell carcinoma
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    Development of a cyst-targeted therapy for polycystic kidney disease using an antagonistic dimeric IgA monoclonal antibody against cMET
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    The antitumor effect of tlr4 inhibition in head and neck cancer cell lines
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    Caulerpin suppresses tumor-associated angiogenesis and tumor growth via Hippo signaling in cervical cancer
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    Hypoxia-Induced PRMT1 Lactylation Drives Vimentin Arginine Asymmetric Dimethylation in Tumor Metastasis
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  35. Aug 2025
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    Uncovering phenotypic inheritance from single cells with Microcolony-seq
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    Design of a selective peptide inhibitor targeting KDM5C demethylase activity
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    CDKL5 regulates the initiation of retrograde axonal transport through CLIP170–dynactin complex formation
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    CLEC18A interacts with sulfated glycosaminoglycans and controls clear cell renal cell carcinoma progression
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    Structural basis of poxvirus fusion regulation and anti-A16/G9 antibody-mediated neutralization and protection
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    Coordinated protein modules define DNA damage responses to carboplatin at single-cell resolution in human ovarian carcinoma models
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    KIDINS220 and InsP8 safeguard the stepwise regulation of phosphate exporter XPR1
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    YTHDF proteins and m6A-RNA clients undergo autophagic turnover during contact inhibition
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    TCF25 serves as a nutrient sensor to orchestrate metabolic adaptation and cell death by enhancing lysosomal acidification under glucose starvation
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    MYC deregulation sensitizes cancer cells to N-myristoyltransferase inhibition
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    Unraveling the impact of crizotinib to promote megakaryopoiesis for alleviating thrombocytopenia in myelodysplastic neoplasms
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    NAIP/NLRC4 inflammasome dynamics in murine enteroids are tuned by NAIP ligand concentration and epithelial cell differentiation
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    Imaging Interorganelle Phospholipid Transport by Extended Synaptotagmins Using Bioorthogonally Tagged Lipids
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    cell.com/cell/abstract/S0092-8674(25)00856-6
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    Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection
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    Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection
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    Optineurin Localization at the Centrosome, Spindle, and Midbody Implies Its Role in Cell Division
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    onlinelibrary.wiley.com/doi/10.1002/cm.70015
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    Ubiquitination of the histone variant mH2A1.2 prevents toxic RAD18 accumulation at a subset of genomic loci upon replication stress
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    NIPSNAP1 and NIPSNAP2 Act as “Eat Me” Signals for Mitophagy
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    Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses
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    Live-cell 3D-SIM of Rift Valley fever virus NSs filaments reveals a polygonal web architecture
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    Integrator promotes the association of TFIID and RNA polymerase II to maintain pluripotency during development
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    Combining Multiplexed CRISPR/Cas9-Nickase and PARP Inhibitors Efficiently and Precisely Targets Cancer Cells
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    Distinct 2-phenyl-imidazo[1, 2α] pyridine derivatives drive ER degradation and selectively impair proliferation of ER+ breast cancer cells via the aryl hydrocarbon receptor
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    AI-directed voxel extraction and volume EM identify intrusions as sites of mitochondrial contact
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  77. Jul 2025
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A conserved CENP-E region mediates BubR1-independent recruitment to the outer corona at mitotic onset
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    Identification of CNOT1-CCR4-NOT as a suppressor of 53BP1-p53-p21 signaling
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    Legionella effector LpPIP recruits protein phosphatase 1 to the mitochondria to induce dephosphorylation of outer membrane proteins
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    Lycium barbarum Glycopeptide Inhibits Colorectal Cancer Cell Proliferation via Activating p53/p21 Pathway and Inducing Cellular Senescence
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    Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice
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    biorxiv.org/content/10.1101/2025.07.23.666448v1
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    A trans-kingdom T6SS RNase effector targeting both prokaryotic and host cells for pathogenesis
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    The Hippo pathway kinase MST1 mediates a feedback loop to maintain NLRP3 inflammasome homeostasis
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    Enhancing transcriptome mapping with rapid PRO-seq profiling of nascent RNA
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    Modular DNA barcoding of nanobodies enables multiplexed in situ protein imaging and high-throughput biomolecule detection
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    A new paradigm of islet adaptations in human pregnancy: insights from immunohistochemistry and proteomics
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    Direct interaction of HMGB1 with SARS-CoV-2 facilitates its infection via RAGE-dependent endocytosis
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