1,055 Matching Annotations
  1. Aug 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  3. www.sciencedirect.com www.sciencedirect.com
    RPL22 is a tumor suppressor in MSI-high cancers and a splicing regulator of MDM4
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    sciencedirect.com/science/article/pii/S2211124724009720
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Engineered Drug 3′UTRMYC1-18 Degrades the c-MYC-STAT5A/B-PD-L1 Complex In Vivo to Inhibit Metastatic Triple-Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11311709/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAS3681, an androgen receptor antagonist, prevents drug resistance driven by aberrant androgen receptor signaling in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11306513/
  6. www.cell.com www.cell.com
    ADP-ribosylome analysis reveals homogeneous DNA-damage-induced serine ADP-ribosylation across wild-type and BRCA-mutant breast cancer cell lines
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    cell.com/cell-reports/fulltext/S2211-1247(24)00762-9
  7. breast-cancer-research.biomedcentral.com breast-cancer-research.biomedcentral.com
    Small molecule inhibitor targeting the Hsp70-Bim protein–protein interaction in estrogen receptor-positive breast cancer overcomes tamoxifen resistance
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    breast-cancer-research.biomedcentral.com/articles/10.1186/s13058-024-01790-0
  8. www.nature.com www.nature.com
    TNFRSF19 promotes endoplasmic reticulum stress-induced paraptosis via the activation of the MAPK pathway in triple-negative breast cancer cells
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    nature.com/articles/s41417-023-00696-x
  9. 52.53.155.43 52.53.155.43
    A novel label-free, pre-equilibrium assay to determine the association and dissociation rate constants of therapeutic antibodies on living cells
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    52.53.155.43/898d8e74ba94791d2618a9f0837530aab54dfc5b/British J Pharmacology - 2023 - Janezic - A novel label-free pre-equilibrium assay to determine the association and-html.html
  10. 52.53.155.43 52.53.155.43
    Cadherin-11 increases tumor cell proliferation and metastatic potential via Wnt pathway activation
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    52.53.155.43/620f08826c7f88548747fa61a5aaaacff016b5d6/Molecular Oncology - 2023 - Liu-html.html
  11. aacrjournals.org aacrjournals.org
    Targeted MDM2 degradation reveals a new vulnerability for p53 inactivated triple negative breast cancer
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    aacrjournals.org/cancerdiscovery/article/13/5/1210/726189/Targeted-MDM2-Degradation-Reveals-a-New
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    ADSCs stimulated by resistin promote breast cancer cell malignancy via CXCL5 in a breast cancer coculture model
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    nature.com/articles/s41598-022-19290-6
  13. www.mdpi.com www.mdpi.com
    Cancer-Associated Fibroblasts Regulate the Plasticity of Breast Cancer Stemness through the Production of Leukemia Inhibitory Factor
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    mdpi.com/2075-1729/11/12/1298/htm
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    Diketopiperazine-Based, Flexible Tadalafil Analogues: Synthesis, Crystal Structures and Biological Activity Profile
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    mdpi.com/1420-3049/26/4/794/htm
  15. pubs.acs.org pubs.acs.org
    Integrated Compound Profiling Screens Identify the Mitochondrial Electron Transport Chain as the Molecular Target of the Natural Products Manassantin, Sesquicillin, and Arctigenin - ACS Chemical Biology (ACS Publications)
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    pubs.acs.org/doi/full/10.1021/cb300495e
  16. Jul 2024
  17. www.biorxiv.org www.biorxiv.org
    The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization
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    biorxiv.org/content/10.1101/2024.07.22.604482v1
  18. www.sciencedirect.com www.sciencedirect.com
    NAMPT-targeting PROTAC and nicotinic acid co-administration elicit safe and robust anti-tumor efficacy in NAPRT-deficient pan-cancers
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    sciencedirect.com/science/article/pii/S2451945624002083
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    Loss of ZNF408 attenuates STING-mediated immune surveillance in breast carcinogenesis
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    sciencedirect.com/science/article/pii/S2589004224015013
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    ‘Radical’ differences between two FLIM microscopes affect interpretation of cell signaling dynamics
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    sciencedirect.com/science/article/pii/S2589004224014937
  21. 52.53.155.43 52.53.155.43
    564418938-html.html
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    Affimer reagents enable targeted delivery of therapeutic agents and RNA via Virus-Like Particles
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    sciencedirect.com/science/article/pii/S2589004224016869
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    FANCM promotes PARP inhibitor resistance by minimizing ssDNA gap formation and counteracting resection inhibition
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    sciencedirect.com/science/article/pii/S2211124724007939
  24. www.sciencedirect.com www.sciencedirect.com
    RNA 5-methylcytosine marks mitochondrial double-stranded RNAs for degradation and cytosolic release
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    sciencedirect.com/science/article/pii/S1097276524005306
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    Systematic dissection of sequence features affecting binding specificity of a pioneer factor reveals binding synergy between FOXA1 and AP-1
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    sciencedirect.com/science/article/pii/S109727652400529X
  26. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16489
  27. www.biorxiv.org www.biorxiv.org
    Osmotic Stress Influences Microtubule Drug Response Via WNK1 Kinase Signaling
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    biorxiv.org/content/10.1101/2024.07.08.602030v1
  28. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A vitamin D-based strategy overcomes chemoresistance in prostate cancer
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16492
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A high-throughput approach to identify BRCA1-downregulating compounds to enhance PARP inhibitor sensitivity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11238136/
  30. link.springer.com link.springer.com
    Cellular Traction Force Holds the Potential as a Drug Testing Readout for In Vitro Cancer Metastasis
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    link.springer.com/article/10.1007/s12195-024-00811-4
  31. www.mdpi.com www.mdpi.com
    HER4 Affects Sensitivity to Tamoxifen and Abemaciclib in Luminal Breast Cancer Cells and Restricts Tumor Growth in MCF-7-Based Humanized Tumor Mice
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    mdpi.com/1422-0067/25/13/7475
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NDRG1 acts as an oncogene in triple-negative breast cancer and its loss sensitizes cells to mitochondrial iron chelation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11231402/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11215406/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: IFNγ mediates the resistance of tumor cells to distinct NK cell subsets
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    ncbi.nlm.nih.gov/pmc/articles/PMC11218003/
  35. Jun 2024
  36. link.springer.com link.springer.com
    Nail fold capillaroscopy as a potential tool to evaluate breast tumor
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    link.springer.com/article/10.1186/s40543-024-00449-x
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An electro-optical platform for the ultrasensitive detection of small extracellular vesicle sub-types and their protein epitope counts
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    ncbi.nlm.nih.gov/pmc/articles/PMC11152657/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRX4204 Induces Senescence and Cell Death in HER2-positive Breast Cancer and Synergizes with Anti-HER2 Therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11145169/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    mitoBKCa is functionally expressed in murine and human breast cancer cells and potentially contributes to metabolic reprogramming
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    ncbi.nlm.nih.gov/pmc/articles/PMC11136494/
  40. May 2024
  41. www.sciencedirect.com www.sciencedirect.com
    Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
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    sciencedirect.com/science/article/pii/S1535610824001697
  42. www.nature.com www.nature.com
    Epigenetic activation of SOX11 is associated with recurrence and progression of ductal carcinoma in situ to invasive breast cancer
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    nature.com/articles/s41416-024-02697-5
  43. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17158
  44. www.sciencedirect.com www.sciencedirect.com
    mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway
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    sciencedirect.com/science/article/pii/S1097276524003939
  45. www.science.org www.science.org
    eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer
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    science.org/doi/10.1126/scisignal.adh4475
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM7A-DT induces genotoxic stress, tumorigenesis, and progression of p53 missense mutation-associated invasive breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11097164/
  47. www.biorxiv.org www.biorxiv.org
    Activation of PKR by a short-hairpin RNA
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    biorxiv.org/content/10.1101/2024.05.08.592371v1
  48. www.sciencedirect.com www.sciencedirect.com
    Protocol for mapping physiological DSBs using in-suspension break labeling in situ and sequencing
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    sciencedirect.com/science/article/pii/S2666166724002247
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neoadjuvant radiotherapy in ER+, HER2+, and triple-negative -specific breast cancer based humanized tumor mice enhances anti-PD-L1 treatment efficacy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11089195/
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Janus kinase 1 is critical for pancreatic cancer initiation and progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11194014/
  51. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17145
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NRN1 interacts with Notch to increase oncogenic STAT3 signaling in melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11071257/
  53. www.sciencedirect.com www.sciencedirect.com
    Targeted blocking of EGFR and GLUT1 by compound H reveals a new strategy for treatment of triple-negative breast cancer and nasopharyngeal carcinoma
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    sciencedirect.com/science/article/pii/S0928098724001003
  54. www.sciencedirect.com www.sciencedirect.com
    Methylation of the chromatin modifier KMT2D by SMYD2 contributes to therapeutic response in hormone-dependent breast cancer
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    sciencedirect.com/science/article/pii/S2211124724005023
  55. link.springer.com link.springer.com
    A novel long non-coding RNA MIR4500HG003 promotes tumor metastasis through miR-483-3p-MMP9 axis in triple-negative breast cancer
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    link.springer.com/article/10.1038/s41419-024-06675-w
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CBF-beta mitigates PI3K-alpha-specific inhibitor killing through PIM1 in PIK3CA mutant gastric cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10811747/
  57. Apr 2024
  58. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAcylation of RBM14 contributes to elevated cellular O-GlcNAc through regulation of OGA protein stability
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    sciencedirect.com/science/article/pii/S2211124724004911
  59. link.springer.com link.springer.com
    Systematic optimization and evaluation of culture conditions for the construction of circulating tumor cell clusters using breast cancer cell lines
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    link.springer.com/article/10.1186/s12885-024-12214-9
  60. www.embopress.org www.embopress.org
    Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia
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    embopress.org/doi/10.1038/s44318-024-00065-w
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PARP inhibitors suppress tumours via centrosome error-induced senescence independent of DNA damage response
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    ncbi.nlm.nih.gov/pmc/articles/PMC11052917/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia
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    ncbi.nlm.nih.gov/pmc/articles/PMC11021510/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context-dependent roles for ubiquitous mitochondrial creatine kinase CKMT1 in breast cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11100297/
  64. www.sciencedirect.com www.sciencedirect.com
    Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
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    sciencedirect.com/science/article/pii/S221112472400439X
  65. link.springer.com link.springer.com
    Functionalized siRNA-chitosan nanoformulations promote triple-negative breast cancer cell death via blocking the miRNA-21/AKT/ERK signaling axis: in-silico and in vitro studies
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    link.springer.com/article/10.1007/s00210-024-03068-w
  66. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel diarylated tacrine derivatives: Synthesis, characterization, anticancer, antiepileptic, antibacterial, and antifungal activities
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    onlinelibrary.wiley.com/doi/10.1002/jbt.23706
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10993856/
  68. www.sciencedirect.com www.sciencedirect.com
    Genetic interactions reveal distinct biological and therapeutic implications in breast cancer
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    sciencedirect.com/science/article/pii/S1535610824000916
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Abemaciclib is effective in palbociclib-resistant hormone receptor-positive metastatic breast cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10592446/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response
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    ncbi.nlm.nih.gov/pmc/articles/PMC10984980/
  71. Mar 2024
  72. www.nature.com www.nature.com
    Light-mediated intracellular polymerization
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    nature.com/articles/s41596-024-00970-8
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Eukaryotic release factor 1 from Euplotes promotes frameshifting at premature stop codons in human cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10952039/
  74. www.sciencedirect.com www.sciencedirect.com
    Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes
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    sciencedirect.com/science/article/pii/S2211124724003000
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF217 Gene Copy Number as a Marker of Response to Standard Therapy Drugs According to ERα Status in Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10950081/
  76. www.biorxiv.org www.biorxiv.org
    PDE4 inhibitor Rolipram represses hedgehog signaling via ubiquitin-mediated proteolysis of GLI transcription factors to regress breast cancer
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    biorxiv.org/content/10.1101/2024.03.03.583221v1
  77. www.sciencedirect.com www.sciencedirect.com
    MTCH2 stimulates cellular proliferation and cycles via PI3K/Akt pathway in breast cancer
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    sciencedirect.com/science/article/pii/S2405844024042038
  78. www.sciencedirect.com www.sciencedirect.com
    De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
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    sciencedirect.com/science/article/pii/S221112472400264X
  79. www.sciencedirect.com www.sciencedirect.com
    A gut-derived hormone regulates cholesterol metabolism
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    sciencedirect.com/science/article/pii/S0092867424002265
  80. www.sciencedirect.com www.sciencedirect.com
    MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors
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    sciencedirect.com/science/article/pii/S2589004224004097
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INX-315, a selective CDK2 inhibitor, induces cell cycle arrest and senescence in solid tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10905675/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification and characterization of a small molecule Bcl-2 Functional Converter
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    ncbi.nlm.nih.gov/pmc/articles/PMC10911799/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of hydroxymethylglutharyl-coenzyme A reductase in the induction of stem-like states in breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10902018/
  84. www.biorxiv.org www.biorxiv.org
    The transcription factor RIP140 regulates interferon γ signaling in breast cancer
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    biorxiv.org/content/10.1101/2024.02.15.580503v1
  85. Feb 2024
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Design, synthesis and biological evaluation of novel podophyllotoxin derivatives as tubulin-targeting anticancer agents
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    ncbi.nlm.nih.gov/pmc/articles/PMC10896134/
  87. 52.53.155.43 52.53.155.43
    cd-23-0954-html.html
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    52.53.155.43/aaf525c30ae01b53e260240fad732783dfb4bbac/cd-23-0954-html.html
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapy-Induced Senescence Contributes to the Efficacy of Abemaciclib in Patients with Dedifferentiated Liposarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10870201/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TOP1 and R-loops facilitate transcriptional DSBs at hypertranscribed cancer driver genes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10875566/
  90. link.springer.com link.springer.com
    Effectiveness of [67Cu]Cu-trastuzumab as a theranostic against HER2-positive breast cancer
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    link.springer.com/article/10.1007/s00259-024-06648-3
  91. www.sciencedirect.com www.sciencedirect.com
    Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting
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    sciencedirect.com/science/article/pii/S1097276524000893
  92. www.sciencedirect.com www.sciencedirect.com
    Increased matrix stiffness enhances pro-tumorigenic traits in a physiologically relevant breast tissue- monocyte 3D model
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