859 Matching Annotations
  1. Jun 2023
  2. www.biorxiv.org www.biorxiv.org
    Tyramine promotes colon cancer risk and development by inducing DNA damage and inflammation
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    biorxiv.org/content/10.1101/2023.05.25.542254v1
  3. May 2023
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evolution of Resistance to Irinotecan in Cancer Cells Involves Generation of Topoisomerase-Guided Mutations in Non-Coding Genome That Reduce the Chances of DNA Breaks
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    ncbi.nlm.nih.gov/pmc/articles/PMC10218574/
  5. 52.53.155.43 52.53.155.43
    A novel EGFR Inhibitor, HNPMI regulates apoptosis and oncogenesis by modulating BCL-2/BAX and p53 in colon cancer
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    52.53.155.43/b51f94c49df43022b2f6198ee4b9b06582c4cb71/British J Pharmacology - 2023 - Kandhavelu - A novel EGFR Inhibitor HNPMI regulates apoptosis and oncogenesis by-html.html
  6. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/55175f335d9d63eca4c96b1d663be208d4b843b1/Molecular Oncology - 2023 - Koob - MND1 enables homologous recombination in somatic cells primarily outside the context of-html.html
  7. www.science.org www.science.org
    Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair
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    science.org/doi/10.1126/sciadv.add8023
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The carboxyl-terminal sequence of PUMA binds to both anti-apoptotic proteins and membranes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10185343/
  9. www.sciencedirect.com www.sciencedirect.com
    MicroRNA-31 induced by Fusobacterium nucleatum infection promotes colorectal cancer tumorigenesis
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    sciencedirect.com/science/article/pii/S2589004223008477
  10. link.springer.com link.springer.com
    Discovery of two new isoforms of the human DUT gene
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    link.springer.com/article/10.1038/s41598-023-32970-1
  11. www.authorea.com www.authorea.com
    The dicarbonyl electrophile scavenger 2-hydroxybenzylamine (2-HOBA) prevents colorectal carcinogenesis and reduces tumor growth
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    authorea.com/users/581352/articles/621972-the-dicarbonyl-electrophile-scavenger-2-hydroxybenzylamine-2-hoba-prevents-colorectal-carcinogenesis-and-reduces-tumor-growth
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair
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    ncbi.nlm.nih.gov/pmc/articles/PMC10171824/
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    Impact of supraphysiologic MDM2 expression on chromatin networks and therapeutic responses in sarcoma
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    sciencedirect.com/science/article/pii/S2666979X23000897
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    Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment
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    sciencedirect.com/science/article/pii/S1550413123001407
  15. www.nature.com www.nature.com
    Venlafaxine antagonizes the noradrenaline-promoted colon cancer progression by inhibiting the norepinephrine transporter
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    nature.com/articles/s41420-023-01447-5
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical Evaluation of ON203, A Novel Bioengineered mAb Targeting Oxidized Macrophage Migration Inhibitory Factor as an Anticancer Therapeutic
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    ncbi.nlm.nih.gov/pmc/articles/PMC10157364/
  17. www.sciencedirect.com www.sciencedirect.com
    KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells
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    sciencedirect.com/science/article/pii/S2211124722008750
  18. Apr 2023
  19. www.biorxiv.org www.biorxiv.org
    Correcting 4sU induced quantification bias in nucleotide conversion RNA-seq data
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    biorxiv.org/content/10.1101/2023.04.21.537786v1
  20. www.sciencedirect.com www.sciencedirect.com
    Fanconi anemia-associated chromosomal radial formation is dependent on POLθ-mediated alternative end joining
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    sciencedirect.com/science/article/pii/S2211124723004394
  21. www.sciencedirect.com www.sciencedirect.com
    Bromodomain protein BRD8 regulates cell cycle progression in colorectal cancer cells through a TIP60-independent regulation of the pre-RC complex
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    sciencedirect.com/science/article/pii/S2589004223006405
  22. www.sciencedirect.com www.sciencedirect.com
    Proteomic discovery of chemical probes that perturb protein complexes in human cells
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    sciencedirect.com/science/article/pii/S1097276523002393
  23. www.sciencedirect.com www.sciencedirect.com
    APC-driven actin nucleation powers collective cell dynamics in colorectal cancer cells
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    sciencedirect.com/science/article/pii/S2589004223006600
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC10102842/
  25. www.science.org www.science.org
    Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasis
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    science.org/doi/10.1126/sciadv.ade3422
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950
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    ncbi.nlm.nih.gov/pmc/articles/PMC10112292/
  27. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Targeting thiol isomerase activity with zafirlukast to treat ovarian cancer from the bench to clinic
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202201952R
  28. www.jove.com www.jove.com
    Extracting Modified Microtubules from Mammalian Cells to Study Microtubule-Protein Complexes by Cryo-Electron Microscopy
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    jove.com/v/65126/extracting-modified-microtubules-from-mammalian-cells-to-study
  29. www.sciencedirect.com www.sciencedirect.com
    Cell-to-cell variability in Myc dynamics drives transcriptional heterogeneity in cancer cells
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    sciencedirect.com/science/article/pii/S2211124723004126
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FEBS Press
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    ncbi.nlm.nih.gov/pmc/articles/PMC10323897/
  31. www.biorxiv.org www.biorxiv.org
    Vitamin D induces SIRT1 activation through K610 deacetylation in colon cancer
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    biorxiv.org/content/10.1101/2023.02.22.529558v2
  32. onlinelibrary.wiley.com onlinelibrary.wiley.com
    An integrated multi-omics analysis of rectal cancer patients identified POU2F3 as a putative druggable target and entinostat as a cytotoxic enhancer of 5-Fluorouracil
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34478
  33. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Dual role of sprouty2 as an inhibitor of RAS/ERK-driven proliferation and a promoter of cancer invasion in KRAS wild-type colorectal cancer
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    onlinelibrary.wiley.com/doi/10.1002/mc.23537
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone H3 phospho-regulation by KimH3 in both interphase and mitosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10066537/
  35. Mar 2023
  36. www.nature.com www.nature.com
    Determining chromatin architecture with Micro Capture-C
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    nature.com/articles/s41596-023-00817-8
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microstructured soft devices for the growth and analysis of populations of homogenous multicellular tumor spheroids
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    ncbi.nlm.nih.gov/pmc/articles/PMC10020259/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GSK-3 inhibitor elraglusib enhances tumor-infiltrating immune cell activation in tumor biopsies and synergizes with anti-PD-L1 in a murine model of colorectal cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9934544/
  39. www.sciencedirect.com www.sciencedirect.com
    FAM193A is a positive regulator of p53 activity
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    sciencedirect.com/science/article/pii/S2211124723002413
  40. genomemedicine.biomedcentral.com genomemedicine.biomedcentral.com
    Identification of specific susceptibility loci for the early-onset colorectal cancer
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    genomemedicine.biomedcentral.com/articles/10.1186/s13073-023-01163-w
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Overexpression of synaptic vesicle protein Rab GTPase 3C promotes vesicular exocytosis and drug resistance in colorectal cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9980308/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pixelated Microfluidics for Drug Screening on Tumour Spheroids and Ex Vivo Microdissected Tumour Explants
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    ncbi.nlm.nih.gov/pmc/articles/PMC9954565/
  43. Feb 2023
  44. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13379
  45. www.sciencedirect.com www.sciencedirect.com
    Recycling of modified H2A-H2B provides short-term memory of chromatin states
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    sciencedirect.com/science/article/pii/S0092867423000077
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Downregulation of iNOS/NO Promotes Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9890133/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR screening reveals a dependency on ribosome recycling for efficient SARS-CoV-2 programmed ribosomal frameshifting and viral replication
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    ncbi.nlm.nih.gov/pmc/articles/PMC9884621/
  48. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    ALKBH1-mediated m1A demethylation of METTL3 mRNA promotes the metastasis of colorectal cancer by downregulating SMAD7 expression
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13366
  49. Jan 2023
  50. www.sciencedirect.com www.sciencedirect.com
    Chimeric efferocytic receptors improve apoptotic cell clearance and alleviate inflammation
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    sciencedirect.com/science/article/pii/S0092867422015045
  51. www.nature.com www.nature.com
    The HDAC inhibitor zabadinostat is a systemic regulator of adaptive immunity
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    nature.com/articles/s42003-023-04485-y
  52. www.science.org www.science.org
    Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis
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    science.org/doi/10.1126/scisignal.abh1083
  53. www.sciencedirect.com www.sciencedirect.com
    Centromeres as universal hotspots of DNA breakage, driving RAD51-mediated recombination during quiescence
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    sciencedirect.com/science/article/pii/S1097276523000047
  54. www.sciencedirect.com www.sciencedirect.com
    Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication
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    sciencedirect.com/science/article/pii/S0092867422015793
  55. www.sciencedirect.com www.sciencedirect.com
    Inositol pyrophosphate profiling reveals regulatory roles of IP6K2-dependent enhanced IP7 metabolism in the enteric nervous system
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    sciencedirect.com/science/article/pii/S0021925823000601
  56. www.biorxiv.org www.biorxiv.org
    The regulatory role of the CD2AP/TKS4 interaction in EMT and its potential as a biomarker for colon cancer
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    biorxiv.org/content/10.1101/2023.01.13.523903v1
  57. www.mdpi.com www.mdpi.com
    Optimized Antimicrobial Peptide Jelleine-I Derivative Br-J-I Inhibits Fusobacterium Nucleatum to Suppress Colorectal Cancer Progression
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    mdpi.com/1422-0067/24/2/1469
  58. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14572
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PhAc-ALGP-Dox, a Novel Anticancer Prodrug with Targeted Activation and Improved Therapeutic Index
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    ncbi.nlm.nih.gov/pmc/articles/PMC9377749/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ANGPTL4-Mediated Promotion of Glycolysis Facilitates the Colonization of Fusobacterium nucleatum in Colorectal Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9397643/
  61. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Chronic acidosis rewires cancer cell metabolism through PPARα signaling
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34404
  62. 52.53.155.43 52.53.155.43
    ccr-22-2088-html.html
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    52.53.155.43/13935f65332ed27c8eea46404a99ca3fb39f2ca4/ccr-22-2088-html.html
  63. Dec 2022
  64. link.springer.com link.springer.com
    Conformation specific antagonistic high affinity antibodies to the RON receptor kinase for imaging and therapy
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    link.springer.com/article/10.1038/s41598-022-26404-7
  65. link.springer.com link.springer.com
    The 3-O sulfation of heparan sulfate proteoglycans contributes to the cellular internalization of tau aggregates
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    link.springer.com/article/10.1186/s12860-022-00462-1
  66. www.cell.com www.cell.com
    Fluorinated triphenylphosphonium analogs improve cell selectivity and in vivo detection of mito-metformin
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    cell.com/iscience/abstract/S2589-0042(22)01942-3
  67. www.sciencedirect.com www.sciencedirect.com
    Increased replication origin firing links replication stress to whole chromosomal instability in human cancer
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    sciencedirect.com/science/article/pii/S2211124722017284
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of insulin‐like growth factor 2 mRNA‐binding protein 1 sensitizes colorectal cancer cells to chemotherapeutics
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    ncbi.nlm.nih.gov/pmc/articles/PMC9721091/
  69. www.sciencedirect.com www.sciencedirect.com
    Cancer cell-derived type I interferons instruct tumor monocyte polarization
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    sciencedirect.com/science/article/pii/S2211124722016527
  70. www.nature.com www.nature.com
    Table 1 Tumor cell lines used to set up common subcutaneous mouse tumor models
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    nature.com/articles/s41596-022-00709-3/tables/1
  71. Nov 2022
  72. www.nature.com www.nature.com
    The Nodewalk assay to quantitate chromatin fiber interactomes in very small cell populations
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    nature.com/articles/s41596-022-00774-8
  73. aacrjournals.org aacrjournals.org
    Potent and selective PTDSS1 inhibitors induce collateral lethality in cancers with PTDSS2 deletion
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    aacrjournals.org/cancerres/article/82/21/4031/709946/Potent-and-Selective-PTDSS1-Inhibitors-Induce
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alternative splicing downstream of EMT enhances phenotypic plasticity and malignant behavior in colon cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9674345/
  75. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15960
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expression of NMU, PPBP and GNG4 in colon cancer and their influences on prognosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9641087/
  77. www.sciencedirect.com www.sciencedirect.com
    AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity
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    sciencedirect.com/science/article/pii/S1097276522010541
  78. www.sciencedirect.com www.sciencedirect.com
    Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature
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    sciencedirect.com/science/article/pii/S2211124722015236
  79. www.nature.com www.nature.com
    A nascent peptide code for translational control of mRNA stability in human cells
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    nature.com/articles/s41467-022-34664-0
  80. www.sciencedirect.com www.sciencedirect.com
    Enhanced DNA repair through droplet formation and p53 oscillations
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    sciencedirect.com/science/article/pii/S0092867422013198
  81. www.sciencedirect.com www.sciencedirect.com
    LncRNA CCTT-mediated RNA-DNA and RNA-protein interactions facilitate the recruitment of CENP-C to centromeric DNA during kinetochore assembly
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    sciencedirect.com/science/article/pii/S109727652200911X
  82. onlinelibrary.wiley.com onlinelibrary.wiley.com
    GERMLINE GAIN-OF-FUNCTION MMP11 VARIANT RESULTS IN AN AGGRESSIVE FORM OF COLORECTAL CANCER
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34289
  83. www.sciencedirect.com www.sciencedirect.com
    Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells
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    sciencedirect.com/science/article/pii/S1097276522009625
  84. 52.53.155.43 52.53.155.43
    ABCC10-mediated Oxaliplatin resistance in colorectal cancer cells was alleviated by intense endoplasmic reticulum stress (ERS) / IRE1α
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    52.53.155.43/ee9544f92d24a784e439b5f8ccd0815fd1dd27bc/f0a3133f-5e3c-40fc-b375-09b76f1fe1f4-html.html
  85. Oct 2022
  86. 52.53.155.43 52.53.155.43
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  87. aacrjournals.org aacrjournals.org
    Selenium modulates cancer cell response to pharmacologic ascorbate
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    aacrjournals.org/cancerres/article/82/19/3486/709413/Selenium-Modulates-Cancer-Cell-Response-to
  88. www.nature.com www.nature.com
    A microfluidic Braille valve platform for on-demand production, combinatorial screening and sorting of chemically distinct droplets
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    nature.com/articles/s41596-022-00740-4
  89. www.sciencedirect.com www.sciencedirect.com
    Cancer-specific T helper shared and neo-epitopes uncovered by expression of the MHC class II master regulator CIITA
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    sciencedirect.com/science/article/pii/S2211124722013353
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decreased DNA damage and improved p53 specificity of RITA analogs
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    ncbi.nlm.nih.gov/pmc/articles/PMC9538593/
  91. www.nature.com www.nature.com
    A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo
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    nature.com/articles/s41467-022-33430-6
  92. www.sciencedirect.com www.sciencedirect.com
    Cytoplasmic SIRT6-mediated ACSL5 deacetylation impedes nonalcoholic fatty liver disease by facilitating hepatic fatty acid oxidation
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    sciencedirect.com/science/article/pii/S1097276522009078
  93. Sep 2022
  94. insight.jci.org insight.jci.org
    HPV E6 regulates therapy responses in oropharyngeal cancer by repressing the PGC-1<b>α</b>/ERR<b>α</b> axis
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    insight.jci.org/articles/view/159600
  95. www.sciencedirect.com www.sciencedirect.com
    Anti-metastatic effects of 1,2,3,4,6-Penta-O-galloyl-β-D-glucose in colorectal cancer: Regulation of cathepsin B-mediated extracellular matrix dynamics and epithelial-to-mesenchymal transition
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