921 Matching Annotations
  1. Dec 2023
  2. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Revisiting the role of endogenous STAT3 in HPV-positive cervical cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/jmv.29230
  3. Nov 2023
  4. www.sciencedirect.com www.sciencedirect.com
    RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks
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    sciencedirect.com/science/article/pii/S1097276523008493
  5. www.sciencedirect.com www.sciencedirect.com
    Targeted perturbation of signaling-driven condensates
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    sciencedirect.com/science/article/pii/S1097276523008602
  6. link.springer.com link.springer.com
    Cell-specific modulation of mitochondrial respiration and metabolism by the pro-apoptotic Bcl-2 family members Bax and Bak
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    link.springer.com/article/10.1007/s10495-023-01917-2
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiple cullin-associated E3 ligases regulate cyclin D1 protein stability
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    ncbi.nlm.nih.gov/pmc/articles/PMC10651173/
  8. www.sciencedirect.com www.sciencedirect.com
    Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy
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    sciencedirect.com/science/article/pii/S2451945623003719
  9. www.sciencedirect.com www.sciencedirect.com
    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
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    sciencedirect.com/science/article/pii/S2211124723013645
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    Deficiency of BCAT2-mediated branched-chain amino acid catabolism promotes colorectal cancer development
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    sciencedirect.com/science/article/pii/S0925443923003071
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    Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis
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    sciencedirect.com/science/article/pii/S1074761323004442
  12. link.springer.com link.springer.com
    TCOF1 promotes the colorectal cancer progression by stabilizing β-catenin
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    link.springer.com/article/10.1007/s12032-023-02218-z
  13. www.sciencedirect.com www.sciencedirect.com
    In vivo bioluminescence imaging of labile iron in xenograft models and liver using FeAL-1, an iron-activatable form of D-luciferin
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    sciencedirect.com/science/article/pii/S2451945623003252
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Matrix stiffness triggers lipid metabolic crosstalk between tumor and stromal cells to mediate bevacizumab resistance in colorectal cancer liver metastases
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    ncbi.nlm.nih.gov/pmc/articles/PMC10618741/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP1 Expression Driven by EWS::FLI1 Transcription Factor Stabilizes Survivin and Mitigates Replication Stress in Ewing Sarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10618738/
  16. aacrjournals.org aacrjournals.org
    MRTX1719 Is an MTA-Cooperative PRMT5 Inhibitor That Exhibits Synthetic Lethality in Preclinical Models and Patients with MTAP-Deleted Cancer
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    aacrjournals.org/cancerdiscovery/article/13/11/2412/729848/MRTX1719-Is-an-MTA-Cooperative-PRMT5-Inhibitor
  17. www.sciencedirect.com www.sciencedirect.com
    Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers
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    sciencedirect.com/science/article/pii/S1074761323004181
  18. Oct 2023
  19. www.sciencedirect.com www.sciencedirect.com
    The intrinsically disordered region of eIF5B stimulates IRES usage and nucleates biological granule formation
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    sciencedirect.com/science/article/pii/S2211124723012950
  20. www.sciencedirect.com www.sciencedirect.com
    BRD4-binding enhancer promotes CRC progression by interacting with YY1 to activate the Wnt pathway through upregulation of TCF7L2
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    sciencedirect.com/science/article/pii/S0006295223004689
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    WIP1 is a novel specific target for growth hormone action
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    ncbi.nlm.nih.gov/pmc/articles/PMC10590974/
  22. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13537
  23. www.mdpi.com www.mdpi.com
    Studying the Association of TKS4 and CD2AP Scaffold Proteins and Their Implications in the Partial Epithelial–Mesenchymal Transition (EMT) Process
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    mdpi.com/1422-0067/24/20/15136
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Complementary CRISPR screen highlights the contrasting role of membrane-bound and soluble ICAM-1 in regulating antigen-specific tumor cell killing by cytotoxic T cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10586807/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatial Profiling of Circular RNAs in Cancer Reveals High Expression in Muscle and Stromal Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10570686/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-content microscopy reveals a morphological signature of bortezomib resistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC10584373/
  27. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/7b3101f3d01462bbcf14399b3becbcb8b341bb38/Molecular Oncology - 2023 - Hsieh - Repositioning VU-0365114 as a novel microtubule-destabilizing agent for treating cancer-html.html
  28. 52.53.155.43 52.53.155.43
    can-23-0025-html.html
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    52.53.155.43/bc5726273c8a813445d20b0a93f388bd5f59a859/can-23-0025-html.html
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Piperlongumine is a ligand for the orphan nuclear receptor 4A1 (NR4A1)
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    ncbi.nlm.nih.gov/pmc/articles/PMC10551445/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Solid Cancers with a Cancer-Specific Monoclonal Antibody to Surface Expressed Aberrantly O-glycosylated Proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC10543972/
  31. Sep 2023
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The identification of high-performing antibodies for Coiled-coil-helix-coiled-coil-helix domain containing protein 10 (CHCHD10) for use in Western Blot, immunoprecipitation and immunofluorescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC10521100/
  33. www.sciencedirect.com www.sciencedirect.com
    Natural killer cell therapy targeting cancer stem cells: Old wine in a new bottle
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    sciencedirect.com/science/article/pii/S0304383523002793
  34. 52.53.155.43 52.53.155.43
    can-23-0025-html.html
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    52.53.155.43/bc5726273c8a813445d20b0a93f388bd5f59a859/can-23-0025-html.html
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenomic analysis reveals a unique DNA methylation program of metastasis-competent circulating tumor cells in colorectal cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10505142/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The autophagic protein FYCO1 controls TNFRSF10/TRAIL receptor induced apoptosis and is inactivated by CASP8 (caspase 8)
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    ncbi.nlm.nih.gov/pmc/articles/PMC10472876/
  37. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Kleszcz-html.html
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    52.53.155.43/bda5ca2ff5fc6352261b5aa6b5327e2f6367b095/British J Pharmacology - 2023 - Kleszcz-html.html
  38. Aug 2023
  39. www.sciencedirect.com www.sciencedirect.com
    exo-FISH: Protocol for detecting DNA breaks in repetitive regions of mammalian genomes
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    sciencedirect.com/science/article/pii/S2666166723004549
  40. 52.53.155.43 52.53.155.43
    Nuclear transport surveillance of p53 by nuclear pores in glioblastoma
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    52.53.155.43/64ae675a86b73874b1bb5c50aa8d9678e93e36d6/PIIS2211124723008938-html.html
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MHC Class II is Induced by IFNγ and Follows Three Distinct Patterns of Expression in Colorectal Cancer Organoids
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    ncbi.nlm.nih.gov/pmc/articles/PMC10411481/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FEBS Press
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    ncbi.nlm.nih.gov/pmc/articles/PMC10399714/
  43. aacrjournals.org aacrjournals.org
    Vincristine Enhances the Efficacy of MEK Inhibitors in Preclinical Models of KRAS-mutant Colorectal Cancer
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    aacrjournals.org/mct/article/22/8/962/727921/Vincristine-Enhances-the-Efficacy-of-MEK
  44. elifesciences.org elifesciences.org
    Vitamin D induces SIRT1 activation through K610 deacetylation in colon cancer
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    elifesciences.org/articles/86913
  45. www.sciencedirect.com www.sciencedirect.com
    DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
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    sciencedirect.com/science/article/pii/S2211124723009385
  46. Jul 2023
  47. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Cheng - Pharmacological targeting of Axin2 suppresses cell growth and metastasis in-html.html
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    52.53.155.43/51180316abfac9593501c4c683749a3ad6cad477/British J Pharmacology - 2023 - Cheng - Pharmacological targeting of Axin2 suppresses cell growth and metastasis in-html.html
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanisms of MCL-1 protein stability induced by MCL-1 antagonists in B-cell malignancies
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    ncbi.nlm.nih.gov/pmc/articles/PMC9852224/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GSK-3 Inhibitor Elraglusib Enhances Tumor-Infiltrating Immune Cell Activation in Tumor Biopsies and Synergizes with Anti-PD-L1 in a Murine Model of Colorectal Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10342141/
  50. www.nature.com www.nature.com
    High-throughput Oligopaint screen identifies druggable 3D genome regulators
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    nature.com/articles/s41586-023-06340-w
  51. www.sciencedirect.com www.sciencedirect.com
    Enhanced bypass of PD-L1 translation reduces the therapeutic response to mTOR kinase inhibitors
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    sciencedirect.com/science/article/pii/S2211124723007751
  52. www.nature.com www.nature.com
    E3 ligase MG53 suppresses tumor growth by degrading cyclin D1
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    nature.com/articles/s41392-023-01458-9
  53. www.sciencedirect.com www.sciencedirect.com
    TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry
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    sciencedirect.com/science/article/pii/S0092867423006451
  54. www.sciencedirect.com www.sciencedirect.com
    Bacterial effector restricts liquid-liquid phase separation of ZPR1 to antagonize host UPRER
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    sciencedirect.com/science/article/pii/S2211124723007118
  55. 52.53.155.43 52.53.155.43
    618530-html.html
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    52.53.155.43/416789ac7df726491b564812e1d36841853b9ba2/Maunscript_BJP_20230110-html.html
  56. Jun 2023
  57. www.sciencedirect.com www.sciencedirect.com
    Protocol to analyze endogenous translesion DNA synthesis in single mammalian cells
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    sciencedirect.com/science/article/pii/S2666166723003283
  58. 52.53.155.43 52.53.155.43
    The ubiquitin E3 ligase MDM2 induces chemoresistance in colorectal cancer by degradation of ING3
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    52.53.155.43/fcf8eb638d53697aa65b86389d0e22b90374ae7c/bgad040 (1)-html.html
  59. www.embopress.org www.embopress.org
    DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres
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    embopress.org/doi/10.15252/embr.202256492
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Released dsDNA‐triggered inflammasomes serve as intestinal radioprotective targets
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    ncbi.nlm.nih.gov/pmc/articles/PMC10276537/
  61. www.sciencedirect.com www.sciencedirect.com
    Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination
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    sciencedirect.com/science/article/pii/S1097276523003829
  62. 52.53.155.43 52.53.155.43
    The identification of high-performing antibodies for Coiled-coil-helix-coiled-coil-helix domain containing protein 10 (CHCHD10) for use in Western Blot, immunoprecipitation and immunofluorescence
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    52.53.155.43/7ca82bf96d7646b3c99e77a42b1df42af8410c8b/05cb805d-1af6-47d7-a0e5-2c25cb48aca8_133479_-_kathleen_southern-html.html
  63. www.biorxiv.org www.biorxiv.org
    Illumina Dark Chemical Matter using the Cell Painting Assay
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    biorxiv.org/content/10.1101/2023.05.31.542818v1
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10236151/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Venetoclax is a potent hepsin inhibitor that reduces the metastatic and prothrombotic phenotypes of hepsin-expressing colorectal cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10235687/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Tumor-suppressive Molecular Axis EP300/circRERE/miR-6837-3p/MAVS Activates Type I IFN Pathway and Antitumor Immunity to Suppress Colorectal Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10233356/
  67. www.biorxiv.org www.biorxiv.org
    Tyramine promotes colon cancer risk and development by inducing DNA damage and inflammation
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    biorxiv.org/content/10.1101/2023.05.25.542254v1
  68. May 2023
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evolution of Resistance to Irinotecan in Cancer Cells Involves Generation of Topoisomerase-Guided Mutations in Non-Coding Genome That Reduce the Chances of DNA Breaks
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    ncbi.nlm.nih.gov/pmc/articles/PMC10218574/
  70. 52.53.155.43 52.53.155.43
    A novel EGFR Inhibitor, HNPMI regulates apoptosis and oncogenesis by modulating BCL-2/BAX and p53 in colon cancer
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    52.53.155.43/b51f94c49df43022b2f6198ee4b9b06582c4cb71/British J Pharmacology - 2023 - Kandhavelu - A novel EGFR Inhibitor HNPMI regulates apoptosis and oncogenesis by-html.html
  71. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/55175f335d9d63eca4c96b1d663be208d4b843b1/Molecular Oncology - 2023 - Koob - MND1 enables homologous recombination in somatic cells primarily outside the context of-html.html
  72. www.science.org www.science.org
    Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair
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    science.org/doi/10.1126/sciadv.add8023
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The carboxyl-terminal sequence of PUMA binds to both anti-apoptotic proteins and membranes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10185343/
  74. www.sciencedirect.com www.sciencedirect.com
    MicroRNA-31 induced by Fusobacterium nucleatum infection promotes colorectal cancer tumorigenesis
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    sciencedirect.com/science/article/pii/S2589004223008477
  75. link.springer.com link.springer.com
    Discovery of two new isoforms of the human DUT gene
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    link.springer.com/article/10.1038/s41598-023-32970-1
  76. www.authorea.com www.authorea.com
    The dicarbonyl electrophile scavenger 2-hydroxybenzylamine (2-HOBA) prevents colorectal carcinogenesis and reduces tumor growth
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    authorea.com/users/581352/articles/621972-the-dicarbonyl-electrophile-scavenger-2-hydroxybenzylamine-2-hoba-prevents-colorectal-carcinogenesis-and-reduces-tumor-growth
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair
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    ncbi.nlm.nih.gov/pmc/articles/PMC10171824/
  78. www.sciencedirect.com www.sciencedirect.com
    Impact of supraphysiologic MDM2 expression on chromatin networks and therapeutic responses in sarcoma
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    sciencedirect.com/science/article/pii/S2666979X23000897
  79. www.sciencedirect.com www.sciencedirect.com
    Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment
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    sciencedirect.com/science/article/pii/S1550413123001407
  80. www.nature.com www.nature.com
    Venlafaxine antagonizes the noradrenaline-promoted colon cancer progression by inhibiting the norepinephrine transporter
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    nature.com/articles/s41420-023-01447-5
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical Evaluation of ON203, A Novel Bioengineered mAb Targeting Oxidized Macrophage Migration Inhibitory Factor as an Anticancer Therapeutic
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    ncbi.nlm.nih.gov/pmc/articles/PMC10157364/
  82. www.sciencedirect.com www.sciencedirect.com
    KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells
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    sciencedirect.com/science/article/pii/S2211124722008750
  83. Apr 2023
  84. www.biorxiv.org www.biorxiv.org
    Correcting 4sU induced quantification bias in nucleotide conversion RNA-seq data
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    biorxiv.org/content/10.1101/2023.04.21.537786v1
  85. www.sciencedirect.com www.sciencedirect.com
    Fanconi anemia-associated chromosomal radial formation is dependent on POLθ-mediated alternative end joining
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    sciencedirect.com/science/article/pii/S2211124723004394
  86. www.sciencedirect.com www.sciencedirect.com
    Bromodomain protein BRD8 regulates cell cycle progression in colorectal cancer cells through a TIP60-independent regulation of the pre-RC complex
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    sciencedirect.com/science/article/pii/S2589004223006405
  87. www.sciencedirect.com www.sciencedirect.com
    Proteomic discovery of chemical probes that perturb protein complexes in human cells
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    sciencedirect.com/science/article/pii/S1097276523002393
  88. www.sciencedirect.com www.sciencedirect.com
    APC-driven actin nucleation powers collective cell dynamics in colorectal cancer cells
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    sciencedirect.com/science/article/pii/S2589004223006600
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC10102842/
  90. www.science.org www.science.org
    Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasis
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    science.org/doi/10.1126/sciadv.ade3422
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950
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