699 Matching Annotations
  1. Mar 2021
  2. www.sciencedirect.com www.sciencedirect.com
    Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth
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    sciencedirect.com/science/article/pii/S1074761320305422
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    RADX controls RAD51 filament dynamics to regulate replication fork stability
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    sciencedirect.com/science/article/pii/S1097276520309576
  4. Feb 2021
  5. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Arctigenin protects against depression by inhibiting microglial activation and neuroinflammation via HMGB1/TLR4/NF‐κB and TNF‐α/TNFR1/NF‐κB pathways
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15261
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atomic structure of a mitochondrial complex I intermediate from vascular plants
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    ncbi.nlm.nih.gov/pmc/articles/PMC7447434/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures reveal gatekeeping of the mitochondrial Ca2+ uniporter by MICU1-MICU2
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    ncbi.nlm.nih.gov/pmc/articles/PMC7434445/
  8. www.cell.com www.cell.com
    The hitchhiker's guide to the periplasm: unexpected molecular interactions of polymyxin B1 in E. coli
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    cell.com/structure/abstract/S0969-2126(21)00009-5
  9. www.cell.com www.cell.com
    Calmodulin binds to Drosophila TRP with an unexpected mode
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    cell.com/structure/abstract/S0969-2126(20)30463-9
  10. europepmc.org europepmc.org
    Adeno-associated virus-binding antibodies detected in cats living in the Northeastern United States lack neutralizing activity
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    europepmc.org/article/MED/32572045
  11. www.cell.com www.cell.com
    Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody
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    cell.com/cell/abstract/S0092-8674(20)30057-X
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of a nucleotide-dependent RCK domain requires binding of a cation cofactor to a conserved site
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    ncbi.nlm.nih.gov/pmc/articles/PMC6957272/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure and mechanism of a phage-encoded SAM lyase revises catalytic function of enzyme family
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    ncbi.nlm.nih.gov/pmc/articles/PMC7877911/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The histone demethylase KDM5 is required for synaptic structure and function at the Drosophila neuromuscular junction
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    ncbi.nlm.nih.gov/pmc/articles/PMC7945993/
  15. www.cell.com www.cell.com
    Cancer-Associated Gain-of-Function Mutations Activate a SWI/SNF-Family Regulatory Hub
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    cell.com/molecular-cell/abstract/S1097-2765(20)30654-7
  16. www.sciencedirect.com www.sciencedirect.com
    Gαo is a major determinant of cAMP signaling in the pathophysiology of movement disorders
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    sciencedirect.com/science/article/pii/S2211124721000310
  17. www.cell.com www.cell.com
    Mimicry of Canonical Translation Elongation Underlies Alanine Tail Synthesis in RQC
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30779-6
  18. Jan 2021
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In silico prediction of structure and function for a large family of transmembrane proteins that includes human Tmem41b
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    ncbi.nlm.nih.gov/pmc/articles/PMC7818093/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Jumbo Phages: A Comparative Genomic Overview of Core Functions and Adaptions for Biological Conflicts
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    ncbi.nlm.nih.gov/pmc/articles/PMC7824862/
  21. elifesciences.org elifesciences.org
    Atomic structures of respiratory complex III 2, complex IV, and supercomplex III 2-IV from vascular plants
    1
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    elifesciences.org/articles/62047
  22. www.sciencedirect.com www.sciencedirect.com
    Impact of WIN site inhibitor on the WDR5 interactome
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    sciencedirect.com/science/article/pii/S2211124720316259
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of bacterial phospholipid transporter MlaFEDB with substrate bound
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    ncbi.nlm.nih.gov/pmc/articles/PMC7790496/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mouse Ifit1b is a cap1-RNA–binding protein that inhibits mouse coronavirus translation and is regulated by complexing with Ifit1c
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7762956/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations
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    ncbi.nlm.nih.gov/pmc/articles/PMC7781601/
  26. Dec 2020
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of the human core transcription-export complex reveals a hub for multivalent interactions
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    ncbi.nlm.nih.gov/pmc/articles/PMC7744094/
  28. www.sciencedirect.com www.sciencedirect.com
    Exploitation of Elevated Extracellular ATP to Specifically Direct Antibody to Tumor Microenvironment
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    sciencedirect.com/science/article/pii/S221112472031531X
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimized Vivid-derived Magnets photodimerizers for subcellular optogenetics in mammalian cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC7735757/
  30. www.sciencedirect.com www.sciencedirect.com
    The Halastavi árva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism
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    sciencedirect.com/science/article/pii/S2211124720314650
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structure of the calcium release-activated calcium channel Orai in an open conformation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7723414/
  32. elifesciences.org elifesciences.org
    The structures of secretory and dimeric immunoglobulin A
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    elifesciences.org/articles/56098
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural ordering of the Plasmodium berghei circumsporozoite protein repeats by inhibitory antibody 3D11
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    ncbi.nlm.nih.gov/pmc/articles/PMC7704109/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large domain movements through the lipid bilayer mediate substrate release and inhibition of glutamate transporters
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    ncbi.nlm.nih.gov/pmc/articles/PMC7682989/
  35. www.sciencedirect.com www.sciencedirect.com
    Hedgehog Pathway Activation Requires Coreceptor-Catalyzed, Lipid-Dependent Relay of the Sonic Hedgehog Ligand
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    sciencedirect.com/science/article/pii/S153458072030719X
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity
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    ncbi.nlm.nih.gov/pmc/articles/PMC7687367/
  37. Nov 2020
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates
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    ncbi.nlm.nih.gov/pmc/articles/PMC7652416/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Investigating the trade-off between folding and function in a multidomain Y-family DNA polymerase
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    ncbi.nlm.nih.gov/pmc/articles/PMC7641590/
  40. Oct 2020
  41. elifesciences.org elifesciences.org
    Allosteric mechanism for KCNE1 modulation of KCNQ1 potassium channel activation
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    elifesciences.org/articles/57680
  42. link.springer.com link.springer.com
    Molecular analysis of a fibrin-degrading enzyme from Bacillus subtilis K2 isolated from the Indonesian soybean-based fermented food moromi
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    link.springer.com/article/10.1007/s11033-020-05898-2
  43. www.sciencedirect.com www.sciencedirect.com
    Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses
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    sciencedirect.com/science/article/pii/S1074761320304465
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch
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    ncbi.nlm.nih.gov/pmc/articles/PMC7577740/
  45. Sep 2020
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for the activation of PLC-γ isozymes by phosphorylation and cancer-associated mutations
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    ncbi.nlm.nih.gov/pmc/articles/PMC7004563/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alternative splicing at neuroligin site A regulates glycan interaction and synaptogenic activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC7486126/
  48. elifesciences.org elifesciences.org
    Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT3 receptor via a common vestibule site
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    elifesciences.org/articles/51511
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of substrate recognition by a polypeptide processing and secretion transporter
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    ncbi.nlm.nih.gov/pmc/articles/PMC6959990/
  50. elifesciences.org elifesciences.org
    Structural insights into the Ca2+-dependent gating of the human mitochondrial calcium uniporter
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    elifesciences.org/articles/60513
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Local frustration determines loop opening during the catalytic cycle of an oxidoreductase
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    ncbi.nlm.nih.gov/pmc/articles/PMC7347389/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deep evolutionary analysis reveals the design principles of fold A glycosyltransferases
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    ncbi.nlm.nih.gov/pmc/articles/PMC7185993/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An ER translocon for multi-pass membrane protein biogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC7505659/
  54. elifesciences.org elifesciences.org
    Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction
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    elifesciences.org/articles/54031
  55. www.sciencedirect.com www.sciencedirect.com
    Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling
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    sciencedirect.com/science/article/pii/S1074761320300753
  56. www.jbc.org www.jbc.org
    Roles of active-site residues in catalysis, substrate binding, cooperativity, and the reaction mechanism of the quinoprotein glycine oxidase
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    jbc.org/content/295/19/6472.full
  57. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    BPS Publications
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    pubmed.ncbi.nlm.nih.gov/32663327/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Indirect sexual selection drives rapid sperm protein evolution in abalone
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    ncbi.nlm.nih.gov/pmc/articles/PMC6952181/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC7367683/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gating and selectivity mechanisms for the lysosomal K+ channel TMEM175
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    ncbi.nlm.nih.gov/pmc/articles/PMC7141809/
  61. elifesciences.org elifesciences.org
    Mechanisms of nucleotide selection by telomerase
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    elifesciences.org/articles/55438
  62. www.sciencedirect.com www.sciencedirect.com
    A WW Tandem-Mediated Dimerization Mode of SAV1 Essential for Hippo Signaling
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    sciencedirect.com/science/article/pii/S2211124720311074
  63. www.sciencedirect.com www.sciencedirect.com
    Cryo-EM Reveals Integrin-Mediated TGF-β Activation without Release from Latent TGF-β
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    sciencedirect.com/science/article/pii/S0092867419313923
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Delineating an extracellular redox-sensitive module in T-type Ca2+ channels
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    ncbi.nlm.nih.gov/pmc/articles/PMC7196644/
  65. elifesciences.org elifesciences.org
    Molecular principles of assembly, activation, and inhibition in epithelial sodium channel
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    elifesciences.org/articles/59038
  66. elifesciences.org elifesciences.org
    Moyamoya disease factor RNF213 is a giant E3 ligase with a dynein-like core and a distinct ubiquitin-transfer mechanism
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    elifesciences.org/articles/56185
  67. elifesciences.org elifesciences.org
    Cryo-EM structure of the lysosomal chloride-proton exchanger CLC-7 in complex with OSTM1
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    elifesciences.org/articles/59555
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alternative splice variants of rhomboid proteins: In silico analysis of database entries for select model organisms and validation of functional potential
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    ncbi.nlm.nih.gov/pmc/articles/PMC7065720/
  69. elifesciences.org elifesciences.org
    Structure of RNA polymerase bound to ribosomal 30S subunit
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    elifesciences.org/articles/28560
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β11-12 linker isomerization governs acid-sensing ion channel desensitization and recovery
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    ncbi.nlm.nih.gov/pmc/articles/PMC7041949/
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling of myristoylation in Toxoplasma gondii reveals an N-myristoylated protein important for host cell penetration
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    ncbi.nlm.nih.gov/pmc/articles/PMC7373427/
  72. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14912
  73. www.cell.com www.cell.com
    Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains
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    cell.com/molecular-cell/abstract/S1097-2765(18)30948-1
  74. www.sciencedirect.com www.sciencedirect.com
    Identification of a G-Protein-Independent Activator of GIRK Channels
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    sciencedirect.com/science/article/pii/S2211124720307506
  75. elifesciences.org elifesciences.org
    Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas
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    elifesciences.org/articles/50004
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate
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    ncbi.nlm.nih.gov/pmc/articles/PMC7112951/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Highly regulated, diversifying NTP-dependent biological conflict systems with implications for the emergence of multicellularity
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    ncbi.nlm.nih.gov/pmc/articles/PMC7159879/
  78. www.frontiersin.org www.frontiersin.org
    Computational Design of a Novel VLP-Based Vaccine for Hepatitis B Virus
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    frontiersin.org/article/10.3389/fimmu.2020.02074/full
  79. www.cell.com www.cell.com
    Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody
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    cell.com/cell/abstract/S0092-8674(20)30057-X
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An ultralong CDRH2 in HCV neutralizing antibody demonstrates structural plasticity of antibodies against E2 glycoprotein
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    ncbi.nlm.nih.gov/pmc/articles/PMC7064334/
  81. elifesciences.org elifesciences.org
    The architecture of EMC reveals a path for membrane protein insertion
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    elifesciences.org/articles/57887
  82. elifesciences.org elifesciences.org
    Patient-specific mutations impair BESTROPHIN1’s essential role in mediating Ca2+-dependent Cl- currents in human RPE
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    elifesciences.org/articles/29914
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C-mannosylation supports folding and enhances stability of thrombospondin repeats
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    ncbi.nlm.nih.gov/pmc/articles/PMC6954052/
  84. elifesciences.org elifesciences.org
    Cryo-EM structures of human ZnT8 in both outward- and inward-facing conformations
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    elifesciences.org/articles/58823
  85. elifesciences.org elifesciences.org
    Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5
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    elifesciences.org/articles/38770
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs
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    ncbi.nlm.nih.gov/pmc/articles/PMC7200160/
  87. www.jbc.org www.jbc.org
    Suramin and NF449 are IP5K inhibitors that disrupt inositol hexakisphosphate–mediated regulation of cullin–RING ligase and sensitize cancer cells to MLN4924/pevonedistat
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    jbc.org/content/295/30/10281.full
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC7289601/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies
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    ncbi.nlm.nih.gov/pmc/articles/PMC7311918/
  90. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14918
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A CLC-ec1 mutant reveals global conformational change and suggests a unifying mechanism for the CLC Cl–/H+ transport cycle
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    ncbi.nlm.nih.gov/pmc/articles/PMC7253180/
  92. elifesciences.org elifesciences.org
    Structure and activation mechanism of the BBSome membrane protein trafficking complex
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    elifesciences.org/articles/53322
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kin discrimination in social yeast is mediated by cell surface receptors of the Flo11 adhesin family
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    ncbi.nlm.nih.gov/pmc/articles/PMC7156268/
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The His-Gly motif of acid-sensing ion channels resides in a reentrant ‘loop’ implicated in gating and ion selectivity
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    ncbi.nlm.nih.gov/pmc/articles/PMC7308080/
  95. europepmc.org europepmc.org
    Adeno-associated virus-binding antibodies detected in cats living in the Northeastern United States lack neutralizing activity
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    europepmc.org/article/MED/32572045
  96. www.sciencedirect.com www.sciencedirect.com
    Salmonella Typhoid Toxin PltB Subunit and Its Non-typhoidal Salmonella Ortholog Confer Differential Host Adaptation and Virulence
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    sciencedirect.com/science/article/pii/S1931312820302328
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atomic structure of a mitochondrial complex I intermediate from vascular plants
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    ncbi.nlm.nih.gov/pmc/articles/PMC7447434/
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures reveal gatekeeping of the mitochondrial Ca2+ uniporter by MICU1-MICU2
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