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  1. Jan 2020
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    Photocrosslinking Activity-Based Probes for Ubiquitin RING E3 Ligases
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    Genetic Heterogeneity of BRAF Fusion Kinases in Melanoma Affects Drug Responses
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    Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers
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    Glutamate Signaling in Hepatic Stellate Cells Drives Alcoholic Steatosis
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    Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth
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    Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5
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    Auto-regulation of Secretory Flux by Sensing and Responding to the Folded Cargo Protein Load in the Endoplasmic Reticulum
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    Reciprocal Effects of Fibroblast Growth Factor Receptor Signaling on Dengue Virus Replication and Virion Production
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    Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Modulates Lifespan
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    Conditional BDNF Delivery from Astrocytes Rescues Memory Deficits, Spine Density, and Synaptic Properties in the 5xFAD Mouse Model of Alzheimer Disease
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      DOI: 10.1523/JNEUROSCI.2121-18.2019

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    Amino alkynylisoquinoline and alkynylnaphthyridine compounds potently inhibit acute myeloid leukemia proliferation in mice
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    Tracing MYC Expression for Small Molecule Discovery
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    Inhibition of LTA4H by bestatin in human and mouse colorectal cancer
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  28. Nov 2018
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    Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC
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    Modulation of DNA Repair Systems in Blind Cavefish during Evolution in Constant Darkness
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    Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors
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    miR‐4725‐3p targeting Stim1 signaling is involved in xanthohumol inhibition of glioma cell invasion
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    Estrogen Regulation of GRK2 Inactivates Kappa Opioid Receptor Signaling Mediating Analgesia, But Not Aversion
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    Divergent Matrix-Remodeling Strategies Distinguish Developmental from Neoplastic Mammary Epithelial Cell Invasion Programs
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    Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM
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    Muscarinic receptor antagonists activate ERK-CREB signaling to augment neurite outgrowth of adult sensory neurons
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    Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
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    SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer
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    Swedish Nerve Growth Factor Mutation (NGFR100W) Defines a Role for TrkA and p75NTR in Nociception
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    Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS
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    Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies
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    Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis
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    Extracellular Matrix Components HAPLN1, Lumican, and Collagen I Cause Hyaluronic Acid-Dependent Folding of the Developing Human Neocortex
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    Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity
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    Loss of PRMT5 Promotes PDGFRα Degradation during Oligodendrocyte Differentiation and Myelination
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    IDH2 Deficiency in Microglia Decreases the Pro-inflammatory Response <Emphasis Type="Italic">via</Emphasis> the ERK and NF-κB Pathways
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    Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles
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    Gain-of-Function Mutation of Card14 Leads to Spontaneous Psoriasis-like Skin Inflammation through Enhanced Keratinocyte Response to IL-17A
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    Loss of STI1‐mediated neuronal survival and differentiation in disease‐associated mutations of prion protein
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    MAP Kinase Cascades Regulate the Cold Response by Modulating ICE1 Protein Stability
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    A Tyrosine Phosphorylation Cycle Regulates Fungal Activation of a Plant Receptor Ser/Thr Kinase
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    CD69 partially inhibits apoptosis and erythroid differentiation via CD24, and their knockdown increase imatinib sensitivity in BCR‐ABL‐positive cells
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    Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity
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    Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes
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    Catch-Up Growth in Zebrafish Embryo Requires Neural Crest Cells Sustained by Irs1 Signaling
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    Oncogenic Role of THOR, a Conserved Cancer/Testis Long Non-coding RNA
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    OsMAPK3 Phosphorylates OsbHLH002/OsICE1 and Inhibits Its Ubiquitination to Activate OsTPP1 and Enhances Rice Chilling Tolerance
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    The Neuroprotective Effect of Thalidomide against Ischemia through the Cereblon-mediated Repression of AMPK Activity
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    β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer
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    Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf)
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    CK2 oppositely modulates L-DOPA induced dyskinesia via striatal projection neurons expressing D1- or D2-receptors
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    Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity.
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    FGF19, FGF21, and an FGFR1/β-Klotho-Activating Antibody Act on the Nervous System to Regulate Body Weight and Glycemia
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    MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma
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    Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas
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    Cannabinoid Receptor Type 1 Agonist ACEA Protects Neurons from Death and Attenuates Endoplasmic Reticulum Stress-Related Apoptotic Pathway Signaling
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    A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants
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  97. Nov 2017
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    A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development
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    Carbon Black Nanoparticles Inhibit Aromatase Expression and Estradiol Secretion in Human Granulosa Cells Through the ERK1/2 Pathway
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  100. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Protease activated receptor 2 controls myelin development, resiliency and repair
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    A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice
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    Endogenous, Regulatory Cysteine Sulfenylation of ERK Kinases in Response to Proliferative Signals
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    Heparan sulfate alterations in extracellular matrix structures and fibroblast growth factor‐2 signaling impairment in the aged neurogenic niche
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    GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia
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    Purinergic receptor P2Y6 contributes to 1‐methyl‐4‐phenylpyridinium‐induced oxidative stress and cell death in neuronal SH‐SY5Y cells
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    Stimulus evoked ERK-dependent phosphorylation of activity-regulated cytoskeleton-associated protein (Arc) regulates its neuronal subcellular localization
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    Crosstalk control and limits of physiological c-Jun N-terminal kinase activity for cell viability and neurite stability in differentiated PC12 cells - ScienceDirect
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    Stabilization of the c-Myc Protein by CAMKIIγ Promotes T Cell Lymphoma
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    EGFR Induces E2F1-Mediated Corticotroph Tumorigenesis
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    The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling
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    Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues
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    Reg2 Expression Is Required for Pancreatic Islet Compensation in Response to Aging and High-Fat Diet–Induced Obesity
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    A Potential Role for Endoplasmic Reticulum Stress in Progesterone Deficiency in Obese Women
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of Ras-ERK Signaling and GSK-3 by Amyloid Precursor Protein and Amyloid Beta Facilitates Neurodegeneration in Alzheimer’s Disease
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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microglial TNFα Induces COX2 and PGI2 Synthase Expression in Spinal Endothelial Cells during Neuropathic Pain
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  121. elifesciences.org elifesciences.org
    The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration
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    YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB
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    elifesciences.org/content/6/e22416
  123. www.sciencedirect.com www.sciencedirect.com
    Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression
    1
    1. scibot 08 Nov 2017
      AB_331646

      Curator: @Zeljana_Babic

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    sciencedirect.com/science/article/pii/S1535610817301022
  124. www.sciencedirect.com www.sciencedirect.com
    Multidimensional Tracking of GPCR Signaling via Peroxidase-Catalyzed Proximity Labeling
    1
    1. scibot 08 Nov 2017
      AB_331646

      Curator: @gabimpine

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    sciencedirect.com/science/article/pii/S0092867417303471
  125. www.sciencedirect.com www.sciencedirect.com
    FGF21 Regulates Metabolism Through Adipose-Dependent and -Independent Mechanisms
    1
    1. scibot 08 Nov 2017
      AB_331646

      Curator: @kaitlinsung

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    sciencedirect.com/science/article/pii/S1550413117301560
  126. www.sciencedirect.com www.sciencedirect.com
    A DNA-Based T Cell Receptor Reveals a Role for Receptor Clustering in Ligand Discrimination
    1
    1. scibot 08 Nov 2017
      AB_331646

      Curator: @gabimpine

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    sciencedirect.com/science/article/pii/S0092867417302854
  127. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth
    1
    1. scibot 08 Nov 2017
      AB_331646

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S009286741631460X
  128. www.sciencedirect.com www.sciencedirect.com
    Multivalent Small-Molecule Pan-RAS Inhibitors
    1
    1. scibot 08 Nov 2017
      AB_331646

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S0092867417301848
  129. www.sciencedirect.com www.sciencedirect.com
    Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory “FADDosome” Complex upon TRAIL Stimulation
    1
    1. scibot 08 Nov 2017
      AB_331646

      Curator: @kaitlinsung

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    sciencedirect.com/science/article/pii/S1097276517300485
  130. www.jneurosci.org www.jneurosci.org
    Consolidation of Goal-Directed Action Depends on MAPK/ERK Signaling in Rodent Prelimbic Cortex
    2
    1. scibot 08 Nov 2017
      RRID:AB_331646

      Curator: @chewbeccax

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      RRID:AB_331646
    2. scibot 08 Nov 2017
      AB_331646

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    jneurosci.org/content/36/47/11974
  131. www.sciencedirect.com www.sciencedirect.com
    A Rapid Induction Mechanism for Lin28a in Trophic Responses
    1
    1. scibot 08 Nov 2017
      AB_331646

      Curator: @Zeljana_Babic

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    sciencedirect.com/science/article/pii/S1097276516308681
  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors
    2
    1. scibot 08 Nov 2017
      AB_331646

      Curator: @gabimpine

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      RRID:AB_331646 RRIDCUR:Validated
    2. scibot 08 Nov 2017
      AB_331646

      Curator: @gabimpine

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    ncbi.nlm.nih.gov/pmc/articles/PMC5241115/
  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Angiopoietin receptor Tie2 is required for vein specification and maintenance via regulating COUP-TFII
    1
    1. scibot 08 Nov 2017
      AB_331646

      Curator: @chewbeccax

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    ncbi.nlm.nih.gov/pmc/articles/PMC5218530/
  134. www.sciencedirect.com www.sciencedirect.com
    Glutamatergic neurotransmission in the prefrontal cortex mediates the suppressive effect of intra-prelimbic cortical infusion of BDNF on cocaine-seeking
    1
    1. scibot 08 Nov 2017
      AB_331646

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S0924977X16308483
  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening
    1
    1. scibot 08 Nov 2017
      RRID:AB_331646

      Curator: @bandrow

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    ncbi.nlm.nih.gov/pmc/articles/PMC5127645/
  136. www.sciencedirect.com www.sciencedirect.com
    SIAH and EGFR, Two RAS Pathway Biomarkers, are Highly Prognostic in Locally Advanced and Metastatic Breast Cancer
    1
    1. scibot 08 Nov 2017
      AB_331646

      Curator: @gabimpine

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    sciencedirect.com/science/article/pii/S2352396416303632
  137. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Protein kinase Cɛ activity regulates mGluR5 surface expression in the rat nucleus accumbens
    1
    1. scibot 08 Nov 2017
      AB_331647

      Curator: @gabimpine

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    onlinelibrary.wiley.com/doi/10.1002/jnr.23868/full
  138. synapse.koreamed.org synapse.koreamed.org
    Palmitoyl Serotonin Inhibits L-dopa-induced Abnormal Involuntary Movements in the Mouse Parkinson Model
    1
    1. scibot 08 Nov 2017
      AB_331646

      Curator: @gabimpine

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    synapse.koreamed.org/DOIx.php
  139. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Regulation of synaptic MAPK/ERK phosphorylation in the rat striatum and medial prefrontal cortex by dopamine and muscarinic acetylcholine receptors
    1
    1. scibot 08 Nov 2017
      AB_331646

      Curator: @gabimpine

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      (Cell Signaling Technology Cat# 9101, RRID:AB_331646)

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    onlinelibrary.wiley.com/doi/10.1002/jnr.23622/full
  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tat 101-Mediated Enhancement of Brain Pericyte Migration Involves Platelet-Derived Growth Factor Subunit B Homodimer: Implications for Human Immunodeficiency Virus-Associated Neurocognitive Disorders
    1
    1. scibot 08 Nov 2017
      AB_331646

      Curator: @jcabotaj

      Curator note: Correct ID --> author added parentheses around RRID

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    ncbi.nlm.nih.gov/pmc/articles/PMC4145180/
  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic Removal of Matrix Metalloproteinase 9 Rescues the Symptoms of Fragile X Syndrome in a Mouse Model
    1
    1. scibot 08 Nov 2017
      AB_331646

      Curator: @gabimpine

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      (Cell Signaling Technology Cat# 9101, RRID:AB_331646)

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    ncbi.nlm.nih.gov/pmc/articles/PMC4107404/
  142. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Protein kinase A directly phosphorylates metabotropic glutamate receptor 5 to modulate its function
    1
    1. scibot 08 Nov 2017
      AB_331646

      Curator: @gabimpine

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      (Cell Signaling Technology Cat# 9101, RRID:AB_331646)

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    onlinelibrary.wiley.com/doi/10.1111/jnc.13038/full
  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of Neuronal Gene Expression and Survival by Basal NMDA Receptor Activity: A Role for Histone Deacetylase 4
    1
    1. scibot 08 Nov 2017
      AB_331646

      Curator: @jcabotaj

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    ncbi.nlm.nih.gov/pmc/articles/PMC4228135/
  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Substance P Exacerbates Dopaminergic Neurodegeneration through Neurokinin-1 Receptor-Independent Activation of Microglial NADPH Oxidase
    1
    1. scibot 08 Nov 2017
      AB_331646

      Curator: @gabimpine

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    ncbi.nlm.nih.gov/pmc/articles/PMC4160779/