3,429 Matching Annotations
  1. May 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Temozolomide promotes glioblastoma stemness expression through senescence-associated reprogramming via HIF1α/HIF2α regulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12009364/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Hydrogel-Based Multiplex Coculture Platform for Retinal Component Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12015949/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting BCL11B in CAR-engineered lymphoid progenitors drives NK-like cell development with prolonged anti-leukemic activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11997514/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development of RelB-targeting small-molecule inhibitors of non-canonical NF-κB signaling with antitumor efficacy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11997474/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An inflammation-associated lncRNA induces neuronal damage via mitochondrial dysfunction
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    pmc.ncbi.nlm.nih.gov/articles/PMC12023888/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-guide RNA Cas9 and enhanced-deletion Cas9 rescue a recurrent USH2A-related splicing defect
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    pmc.ncbi.nlm.nih.gov/articles/PMC11999688/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Changes in adrenoceptor expression level contribute to the cellular plasticity of glioblastoma cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12002996/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The E3 ubiquitin ligase RNF126 facilitates quality control of unimported mitochondrial membrane proteins
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    pmc.ncbi.nlm.nih.gov/articles/PMC12005277/
  10. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225008958-main-html.html
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    52.53.155.43/3124e289592a3629f97e02aa5117cdb2659dc765/1-s2.0-S2589004225008958-main-html.html
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    1-s2.0-S2589004225008090-main-html.html
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    52.53.155.43/9127131bdf1d38e6512c3fe44ba4bd8593683c0c/1-s2.0-S2589004225008090-main-html.html
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    IRE1α promotes phagosomal calcium flux to enhance macrophage fungicidal activity
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    cell.com/cell-reports/fulltext/S2211-1247(25)00465-6
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    Condensation-dependent multivalent interactions of EB1 and CENP-R regulate chromosome oscillations in mitosis
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    sciencedirect.com/science/article/pii/S2211124725003316
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    Immunosequencing identifies signatures of T cell responses for early detection of nasopharyngeal carcinoma
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    sciencedirect.com/science/article/pii/S1535610825001680
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Accumulation of Damaging Lipids in the Arf1-Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12021055/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LINC01235 Promotes Clonal Evolution through DNA Replication Licensing‐Induced Chromosomal Instability in Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11984920/
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    The m5C methyltransferase NSUN2 promotes progression of acute myeloid leukemia by regulating serine metabolism
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    sciencedirect.com/science/article/pii/S2211124725004322
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of neurofibromin induces inflammatory macrophage phenotypic switch and retinal neovascularization via GLUT1 activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12184535/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Unraveling the Role of NeuroD2 in Ischemic Pathophysiology: Insight into Neuroprotection Mechanisms Associated with AKT Survival Kinase
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    pmc.ncbi.nlm.nih.gov/articles/PMC12003519/
  20. Apr 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optogenetically engineered Septin-7 enhances immune cell infiltration of tumor spheroids
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    pmc.ncbi.nlm.nih.gov/articles/PMC11536090/
  22. www.nature.com www.nature.com
    Metastatic medulloblastoma remodels the local leptomeningeal microenvironment to promote further metastatic colonization and growth
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    nature.com/articles/s41556-025-01660-7
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    Pooled tagging and hydrophobic targeting of endogenous proteins for unbiased mapping of unfolded protein responses
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    sciencedirect.com/science/article/pii/S1097276525003053
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    Aberrant phase separation drives membranous organelle remodeling and tumorigenesis
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    sciencedirect.com/science/article/pii/S1097276525003041
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    SLIRP amplifies antiviral signaling via positive feedback regulation and contributes to autoimmune diseases
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    sciencedirect.com/science/article/pii/S2211124725003596
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FGFR2 residence in primary cilia is necessary for epithelial cell signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12010920/
  27. www.nature.com www.nature.com
    Far-red chemigenetic kinase biosensors enable multiplexed and super-resolved imaging of signaling networks
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    nature.com/articles/s41587-025-02642-8
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    Requirements for the neurodevelopmental disorder-associated gene ZNF292 in human cortical interneuron development and function
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    sciencedirect.com/science/article/pii/S2211124725003687
  29. 52.53.155.43 52.53.155.43
    rational-design-and-development-of-selective-brd7-bromodomain-inhibitors-and-their-activity-in-prostate-cancer-html.html
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    52.53.155.43/fbc444166f400a01dc32894063d12537e1e236f5/rational-design-and-development-of-selective-brd7-bromodomain-inhibitors-and-their-activity-in-prostate-cancer-html.html
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Human long noncoding RNA VILMIR is induced by major respiratory viral infections and modulates the host interferon response
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    pmc.ncbi.nlm.nih.gov/articles/PMC11998520/
  31. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70099
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    p53 regulates DREAM complex-mediated repression in a p21-independent manner
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    pmc.ncbi.nlm.nih.gov/articles/PMC12000331/
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    The SWI/SNF PBAF complex facilitates REST occupancy at repressive chromatin
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    sciencedirect.com/science/article/pii/S109727652500303X
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    Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation
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    sciencedirect.com/science/article/pii/S153561082500128X
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BET degraders reveal BRD4 disruption of 7SK and P-TEFb is critical for effective reactivation of latent HIV in CD4+ T-cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11998493/
  36. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Comparative single-cell transcriptomic profiling of patient-derived renal carcinoma cells in cellular and animal models of kidney cancer
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70022
  37. 52.53.155.43 52.53.155.43
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    Rewriting regulatory DNA to dissect and reprogram gene expression
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    sciencedirect.com/science/article/pii/S0092867425003526
  41. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SRPK1 Activation Facilitates Gli3S664 Phosphorylation and Promotes Metastasis in Esophageal Squamous Cell Carcinoma
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    onlinelibrary.wiley.com/doi/full/10.1002/mc.23913
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    Phosphorylation-dependent charge blocks regulate the relaxation of nuclear speckle networks
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    sciencedirect.com/science/article/pii/S1097276525002606
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    Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity
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    sciencedirect.com/science/article/pii/S0092867425002909
  44. 52.53.155.43 52.53.155.43
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    52.53.155.43/1d7f3a53d05f85c55a541cebaae421bfbc1ec25f/PDF-html.html
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    Radiotherapy promotes cuproptosis and synergizes with cuproptosis inducers to overcome tumor radioresistance
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    sciencedirect.com/science/article/pii/S1535610825001321
  46. www.sciencedirect.com www.sciencedirect.com
    Library-based single-cell analysis of CAR signaling reveals drivers of in vivo persistence
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    sciencedirect.com/science/article/pii/S2405471225000936
  47. www.nature.com www.nature.com
    Heritable maintenance of chromatin modifications confers transcriptional memory of interferon-γ signaling
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    nature.com/articles/s41594-025-01522-8
  48. www.sciencedirect.com www.sciencedirect.com
    MLKL activity requires a splicing-regulated, druggable intramolecular interaction
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    sciencedirect.com/science/article/pii/S109727652500259X
  49. www.sciencedirect.com www.sciencedirect.com
    Quiescent cell re-entry is limited by macroautophagy-induced lysosomal damage
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    sciencedirect.com/science/article/pii/S009286742500282X
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ORMDL3 restrains type I interferon signaling and anti-tumor immunity by promoting RIG-I degradation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11932694/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Pseudotyped Replication-Deficient VSV with Spike from PEDV Induces Neutralizing Antibody Against PEDV
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    pmc.ncbi.nlm.nih.gov/articles/PMC11946067/
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Urine of Cats with Severe Fever with Thrombocytopenia Syndrome: A Potential Source of Infection Transmission
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    pmc.ncbi.nlm.nih.gov/articles/PMC11944789/
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interplay Between TGFβ1 Signaling and Cancer-Testis Antigen MAGEB2: A New Thorn in Cancer’s Side?
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    pmc.ncbi.nlm.nih.gov/articles/PMC11942090/
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glycosylation Regulation by TMEM230 in Aging and Autoimmunity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11942208/
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-cell sequencing combined with urinary multi-omics analysis reveals that the non-invasive biomarker PRDX5 regulates bladder cancer progression through ferroptosis signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC11931876/
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular control of PDPNhi macrophage subset induction by ADAP as a host defense in sepsis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11949065/
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LNS8801: An Enantiomerically Pure Agonist of the G Protein–Coupled Estrogen Receptor Suitable for Clinical Development
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    pmc.ncbi.nlm.nih.gov/articles/PMC11969138/
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-scale CRISPR/Cas9 screening reveals the role of PSMD4 in colibactin-mediated cell cycle arrest
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    pmc.ncbi.nlm.nih.gov/articles/PMC11934320/
  59. www.science.org www.science.org
    Drosophila and human Headcase define a new family of ribonucleotide granule proteins required for stress response
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    science.org/doi/10.1126/sciadv.ads2086
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antigenic cancer persister cells survive direct T cell attack
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    pmc.ncbi.nlm.nih.gov/articles/PMC11956947/
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Delta-catenin is required for cell proliferation in virus positive Merkel cell carcinoma cell lines but not in human fibroblasts
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    pmc.ncbi.nlm.nih.gov/articles/PMC11952379/
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CREB-family transcription factors and vasopressin-mediated regulation of Aqp2 gene transcription
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    pmc.ncbi.nlm.nih.gov/articles/PMC11952463/
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antibody reactivity against EBNA1 and GlialCAM differentiates multiple sclerosis patients from healthy controls
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    pmc.ncbi.nlm.nih.gov/articles/PMC11929495/
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    m6A modification regulates cell proliferation via reprogramming the balance between glycolysis and pentose phosphate pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11947274/
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metabolic constraint of human telomere length by nucleotide salvage efficiency
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    pmc.ncbi.nlm.nih.gov/articles/PMC11950188/
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide CRISPR screen identifies BUB1 kinase as a druggable vulnerability in malignant pleural mesothelioma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11968822/
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Overexpression of βTrCP1 elicits cell death in cisplatin-induced senescent cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11937513/
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LL37 complexed to double-stranded RNA induces RIG-I-like receptor signalling and Gasdermin E activation facilitating IL-36γ release from keratinocytes
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    pmc.ncbi.nlm.nih.gov/articles/PMC11929817/
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Methylstat sensitizes ovarian cancer cells to PARP-inhibition by targeting the histone demethylases JMJD1B/C
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    pmc.ncbi.nlm.nih.gov/articles/PMC11946898/
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual CARM1-and IKZF3-targeting: A novel approach to multiple myeloma therapy synergy between CARM1 inhibition and IMiDs
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    pmc.ncbi.nlm.nih.gov/articles/PMC11930131/
  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting FANCM by antisense oligonucleotides in ALT-positive cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11930073/
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HRP2 regulating MICU1-mediated Ca2+ overload to dictate chemoresistance of multiple myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11930454/
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CCCTC-binding factor N-terminal domain regulates clustered protocadherin gene expression by enhancing cohesin processivity[image]
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    pmc.ncbi.nlm.nih.gov/articles/PMC11968269/
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    Ligand-induced assembly of antibody variable fragments for the chemical regulation of biological processes
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    sciencedirect.com/science/article/pii/S2451945625000303
  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bioinformatics Identification of Lactate‐Associated Genes in Hepatocellular Carcinoma: G6PD's Role in Immune Modulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11927016/
  76. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KPNA5 Suppresses Malignant Progression of Ovarian Cancer Through Importing the PTPN4 Into the Nucleus
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    pmc.ncbi.nlm.nih.gov/articles/PMC11947769/
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GNE‐317 Reverses MSN‐Mediated Proneural‐to‐Mesenchymal Transition and Suppresses Chemoradiotherapy Resistance in Glioblastoma via PI3K/mTOR
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    pmc.ncbi.nlm.nih.gov/articles/PMC11948001/
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Models of Early Resistance to CDK4/6 Inhibitors Unveil Potential Therapeutic Treatment Sequencing
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    pmc.ncbi.nlm.nih.gov/articles/PMC11942273/
  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tobacco smoke exposure is a driver of altered oxidative stress response and immunity in head and neck cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11971752/
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Light-induced expression of gRNA allows for optogenetic gene editing of T lymphocytes in vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC11925727/
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cooperative role of PACT and ADAR1 in preventing aberrant PKR activation by self-derived double-stranded RNA
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    pmc.ncbi.nlm.nih.gov/articles/PMC11971382/
  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FOXM1 expression reverts aging chromatin profiles through repression of the senescence-associated pioneer factor AP-1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11937471/
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting PI3K inhibitor resistance in breast cancer with metabolic drugs
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    pmc.ncbi.nlm.nih.gov/articles/PMC11926384/
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Harmine promotes axon regeneration through enhancing glucose metabolism
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    pmc.ncbi.nlm.nih.gov/articles/PMC11927705/
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PI(3,4,5)P3-mediated Cdc42 activation regulates macrophage podosome assembly
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    pmc.ncbi.nlm.nih.gov/articles/PMC11933580/
  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR screens with trastuzumab emtansine in HER2-positive breast cancer cell lines reveal new insights into drug resistance
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  179. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  180. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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