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Sep 2024
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Identification of high-performing antibodies for SPARC-related modular calcium-binding protein 1 (SMOC-1) for use in Western Blot and immunoprecipitation

1
1. scibot 25 Sep 2024
  
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  CVCL_0030
  
  DOI: 10.12688/f1000research.141800.2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11406118/
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Redox-dependent condensation and cytoplasmic granulation by human ssDNA-binding protein-1 delineate roles in oxidative stress response

1
1. scibot 25 Sep 2024
  
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  RRID:CVCL_0030
  
  DOI: 10.1016/j.isci.2024.110788
  
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sciencedirect.com/science/article/pii/S2589004224020133
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Differential Requirements for Centrioles in Mitotic Centrosome Growth and Maintenance

1
1. scibot 25 Sep 2024
  
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  RRID:CVCL_1922
  
  DOI: 10.1016/j.devcel.2019.06.004
  
  Resource: (RRID:CVCL_1922)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1534580719305222
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Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition

1
1. scibot 25 Sep 2024
  
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  RRID:CVCL_0045
  
  DOI: 10.1016/j.molcel.2019.03.041
  
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  Curator: @ethanbadger
  
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  RRIDCUR:Incorrect RRID:CVCL_0030 RRID:CVCL_0045
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sciencedirect.com/science/article/pii/S1097276519302709
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C9orf72 Poly(PR) Dipeptide Repeats Disturb Biomolecular Phase Separation and Disrupt Nucleolar Function

1
1. scibot 25 Sep 2024
  
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  RRID:CVCL_0042
  
  DOI: 10.1016/j.molcel.2019.03.019
  
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sciencedirect.com/science/article/pii/S1097276519302230
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Untitled document

1
1. scibot 25 Sep 2024
  
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  RRID:CVCL_0045
  
  DOI: 10.1016/j.molcel.2019.01.033
  
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sciencedirect.com/science/article/pii/S109727651930053X
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Dynamic phosphorylation of FOXA1 by Aurora B guides post-mitotic gene reactivation

1
1. scibot 17 Sep 2024
  
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  CCL-2
  
  DOI: 10.1016/j.celrep.2024.114739
  
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sciencedirect.com/science/article/pii/S2211124724010908
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Systems mapping of bidirectional endosomal transport through the crowded cell

2
1. scibot 17 Sep 2024
  
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  RRID: CVCL_0030
  
  DOI: 10.1016/j.cub.2024.08.026
  
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2. scibot 17 Sep 2024
  
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  CVCL_0030
  
  DOI: 10.1016/j.cub.2024.08.026
  
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sciencedirect.com/science/article/pii/S0960982224011382
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Multi-omics analysis using antibody-based in situ biotinylation technique suggests the mechanism of Cajal body formation

1
1. scibot 17 Sep 2024
  
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  CCL-2
  
  DOI: 10.1016/j.celrep.2024.114734
  
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sciencedirect.com/science/article/pii/S2211124724010854
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The ULK1 effector BAG2 regulates autophagy initiation by modulating AMBRA1 localization

1
1. scibot 13 Sep 2024
  
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  CRM-CCl-2
  
  DOI: 10.1016/j.celrep.2024.114689
  
  Resource: (TKG Cat# TKG 0331, RRID:CVCL_0030)
  
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sciencedirect.com/science/article/pii/S2211124724010404
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TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival

1
1. scibot 12 Sep 2024
  
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  Cat# CCL-2
  
  DOI: 10.1016/j.cell.2024.08.020
  
  Resource: (TKG Cat# TKG 0331, RRID:CVCL_0030)
  
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sciencedirect.com/science/article/pii/S0092867424009115
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Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis

1
1. scibot 11 Sep 2024
  
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  CCL-2
  
  DOI: 10.1016/j.celrep.2024.114728
  
  Resource: (TKG Cat# TKG 0331, RRID:CVCL_0030)
  
  Curator: @vtello
  
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sciencedirect.com/science/article/pii/S2211124724010799
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Five miRNAs identified in fucosylated extracellular vesicles as non-invasive diagnostic signatures for hepatocellular carcinoma

1
1. scibot 06 Sep 2024
  
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  Cat# CCL-2
  
  DOI: 10.1016/j.xcrm.2024.101716
  
  Resource: (TKG Cat# TKG 0331, RRID:CVCL_0030)
  
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sciencedirect.com/science/article/pii/S2666379124004373
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Proteome-scale characterisation of motif-based interactome rewiring by disease mutations

1
1. scibot 05 Sep 2024
  
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  CCL2
  
  DOI: 10.1038/s44320-024-00055-4
  
  Resource: (TKG Cat# TKG 0331, RRID:CVCL_0030)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11369174/
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A compact, versatile drug-induced splicing switch system with minimal background expression

1
1. scibot 05 Sep 2024
  
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  CCL-2
  
  DOI: 10.1016/j.crmeth.2024.100842
  
  Resource: (TKG Cat# TKG 0331, RRID:CVCL_0030)
  
  Curator: @vtello
  
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sciencedirect.com/science/article/pii/S2667237524002157
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E3 ubiquitin ligase ANKIB1 attenuates antiviral immune responses by promoting K48-linked polyubiquitination of MAVS

1
1. scibot 04 Sep 2024
  
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  CVCL_0030
  
  DOI: 10.1016/j.celrep.2024.114687
  
  Resource: (TKG Cat# TKG 0331, RRID:CVCL_0030)
  
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sciencedirect.com/science/article/pii/S2211124724010386
Aug 2024
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The RNA-binding protein EIF4A3 promotes axon development by direct control of the cytoskeleton

1
1. scibot 27 Aug 2024
  
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  RRID:CVCL_0030
  
  DOI: 10.1016/j.celrep.2024.114666
  
  Resource: (TKG Cat# TKG 0331, RRID:CVCL_0030)
  
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sciencedirect.com/science/article/pii/S2211124724010179
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Engineering acyclovir-induced RNA nanodevices for reversible and tunable control of aptamer function

1
1. scibot 27 Aug 2024
  
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  RRID:CVCL_0030
  
  DOI: 10.1016/j.chembiol.2024.07.017
  
  Resource: (TKG Cat# TKG 0331, RRID:CVCL_0030)
  
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sciencedirect.com/science/article/pii/S2451945624003192
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A PDE3A-SLFN12 Molecular Glue Exhibits Significant Antitumor Activity in TKI-Resistant Gastrointestinal Stromal Tumors

1
1. scibot 22 Aug 2024
  
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  RRID:CVCL_0030
  
  DOI: 10.1158/1078-0432.CCR-24-0096
  
  Resource: (TKG Cat# TKG 0331, RRID:CVCL_0030)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11325149/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A proteome-wide quantitative platform for nanoscale spatially resolved extraction of membrane proteins into native nanodiscs

1
1. scibot 22 Aug 2024
  
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  RRID:CVCL_0030
  
  DOI: 10.1101/2024.02.10.579775
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10888908/
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The Chlamydia effector IncE employs two short linear motifs to reprogram host vesicle trafficking

1
1. scibot 22 Aug 2024
  
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  RRID:CVCL_0030
  
  DOI: 10.1016/j.celrep.2024.114624
  
  Resource: (BCRC Cat# 60005, RRID:CVCL_0030)
  
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sciencedirect.com/science/article/pii/S2211124724009744
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Northern blotting of endogenous full-length human-specific LINE-1 RNA

1
1. scibot 22 Aug 2024
  
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  RRID:CVCL_0030
  
  DOI: 10.1093/biomethods/bpae036
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11320832/
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Human AKR1C3 binds agonists of GPR84 and participates in an expanded polyamine pathway

1
1. scibot 20 Aug 2024
  
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  Cat# CCL-2
  
  DOI: 10.1016/j.chembiol.2024.07.011
  
  Resource: (TKG Cat# TKG 0331, RRID:CVCL_0030)
  
  Curator: @vtello
  
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sciencedirect.com/science/article/pii/S2451945624003131
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The deubiquitinase BAP1 and E3 ligase UBE3C sequentially target IRF3 to activate and resolve the antiviral innate immune response

1
1. scibot 20 Aug 2024
  
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  RRID:CVCL_0030
  
  DOI: 10.1016/j.celrep.2024.114608
  
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sciencedirect.com/science/article/pii/S2211124724009586
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Small GTPase ActIvitY ANalyzing (SAIYAN) system: A method to detect GTPase activation in living cells

1
1. scibot 20 Aug 2024
  
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  RRID:CVCL_0030
  
  DOI: 10.1083/jcb.202403179
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11303508/
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µPhos: a scalable and sensitive platform for high-dimensional phosphoproteomics

1
1. scibot 19 Aug 2024
  
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  RRID:CVCL_0030
  
  DOI: 10.1038/s44320-024-00050-9
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11297287/
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Protocol for analyzing TRAIL- and Fas-induced signaling complexes by immunoprecipitation from human cells

1
1. scibot 13 Aug 2024
  
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  CRM-CCL-2
  
  DOI: 10.1016/j.xpro.2024.103126
  
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sciencedirect.com/science/article/pii/S2666166724002910
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Protocol for machine-learning-based 3D image analysis of nuclear envelope tubules in cultured cells

1
1. scibot 13 Aug 2024
  
  in Public
  
  ATCC# CCL-2
  
  DOI: 10.1016/j.xpro.2024.103214
  
  Resource: (TKG Cat# TKG 0331, RRID:CVCL_0030)
  
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sciencedirect.com/science/article/pii/S2666166724003794
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Zinc transporter 1 functions in copper uptake and cuproptosis

1
1. scibot 13 Aug 2024
  
  in Public
  
  CCL-2
  
  DOI: 10.1016/j.cmet.2024.07.009
  
  Resource: (ICLC Cat# HTL95023, RRID:CVCL_0030)
  
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sciencedirect.com/science/article/pii/S1550413124002791
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Purinosomes spatially co-localize with mitochondrial transporters

1
1. scibot 13 Aug 2024
  
  in Public
  
  HeLa
  
  DOI: 10.1016/j.jbc.2024.107620
  
  Resource: (TKG Cat# TKG 0331, RRID:CVCL_0030)
  
  Curator: @vtello
  
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sciencedirect.com/science/article/pii/S0021925824021215
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Increased viral tolerance mediates by antiviral RNA interference in bat cells

1
1. scibot 13 Aug 2024
  
  in Public
  
  Cat# CCL-2
  
  DOI: 10.1016/j.celrep.2024.114581
  
  Resource: (BCRC Cat# 60005, RRID:CVCL_0030)
  
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sciencedirect.com/science/article/pii/S2211124724009100
onlinelibrary.wiley.com onlinelibrary.wiley.com

SNX32 Regulates Sorting and Trafficking of Activated EGFR to the Lysosomal Degradation Pathway

1
1. scibot 13 Aug 2024
  
  in Public
  
  CCL-2
  
  DOI: 10.1111/tra.12952
  
  Resource: (TKG Cat# TKG 0331, RRID:CVCL_0030)
  
  Curator: @dhovakimyan1
  
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  DOI:10.1111/tra.12952 RRID:CVCL_0030
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onlinelibrary.wiley.com/doi/10.1111/tra.12952
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Cryo-EM structure of monomeric CXCL12-bound CXCR4 in the active state

1
1. scibot 13 Aug 2024
  
  in Public
  
  Cat# CCL2
  
  DOI: 10.1016/j.celrep.2024.114578
  
  Resource: (BCRC Cat# 60005, RRID:CVCL_0030)
  
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sciencedirect.com/science/article/pii/S2211124724009070
www.cell.com www.cell.com

Structural insights into ligand recognition and activation of the succinate receptor SUCNR1

1
1. scibot 13 Aug 2024
  
  in Public
  
  CCL2
  
  DOI: 10.1016/j.celrep.2024.114381
  
  Resource: (ICLC Cat# HTL95023, RRID:CVCL_0030)
  
  Curator: @dhovakimyan1
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00709-5
www.cell.com www.cell.com

SigmaR1 shapes rough endoplasmic reticulum membrane sheets

1
1. scibot 13 Aug 2024
  
  in Public
  
  CCL-2
  
  DOI: 10.1016/j.devcel.2024.06.005
  
  Resource: (TKG Cat# TKG 0331, RRID:CVCL_0030)
  
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cell.com/developmental-cell/fulltext/S1534-5807(24)00382-4
www.nature.com www.nature.com

The DNA-repair protein APE1 participates with hnRNPA2B1 to motif-enriched and prognostic miRNA secretion

1
1. scibot 13 Aug 2024
  
  in Public
  
  HeLa
  
  DOI: 10.1038/s41388-024-03039-8
  
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Properties of biomolecular condensates defined by the receptor independent activator of G protein Signaling 3 (AGS3)

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GRB2 is a BECN1 interacting protein that regulates autophagy.

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FEBS Press

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52.53.155.43/7b3101f3d01462bbcf14399b3becbcb8b341bb38/Molecular Oncology - 2023 - Hsieh - Repositioning VU-0365114 as a novel microtubule-destabilizing agent for treating cancer-html.html
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BTApep-TAT peptide inhibits ADP-ribosylation of BORIS to induce DNA damage in cancer

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Ca<sup>2+</sup> entry through mechanotransduction channels localizes BAIAP2L2 to stereocilia tips

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M. tuberculosis PknG manipulates host autophagy flux to promote pathogen intracellular survival

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Analysis of Orientia tsutsugamushi promoter activity

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Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication

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Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation

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Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1

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Diketopiperazine-Based, Flexible Tadalafil Analogues: Synthesis, Crystal Structures and Biological Activity Profile

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Untitled document

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The membrane transporter SLC25A48 enables transport of choline into human mitochondria.

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Protocol for constructing tumor-targeting ANM-PROTACs for degradation of transcription factors

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Identification of the main barriers to Ku accumulation in chromatin

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N-Myristoyltransferase Inhibition causes Mitochondrial Iron Overload and Parthanatos in TIM17A-dependent Aggressive Lung Carcinoma

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ATAD1 prevents clogging of TOM and damage caused by un-imported mitochondrial proteins

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Assembly mechanism of Integrator’s RNA cleavage module

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PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection

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Translocational attenuation mediated by the PERK-SRP14 axis is a protective mechanism of unfolded protein response

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Stress-dependent condensate formation regulated by the ubiquitin-related modifier Urm1

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Miga-mediated endoplasmic reticulum–mitochondria contact sites regulate neuronal homeostasis

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Metformin induces ZFP36 by mTORC1 inhibition in cervical cancer-derived cell lines

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‘Radical’ differences between two FLIM microscopes affect interpretation of cell signaling dynamics

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Characterising replisome disassembly in human cells

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564418938-html.html

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Protocol for iterative indirect immunofluorescence imaging in cultured cells, tissue sections, and metaphase chromosome spreads

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µPhos: a scalable and sensitive platform for high-dimensional phosphoproteomics

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Novel proteolytic activation of Ebolavirus glycoprotein GP by TMPRSS2 and cathepsin L at an uncharted position can compensate for furin cleavage

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Leveraging a self-cleaving peptide for tailored control in proximity labeling proteomics

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Base-resolution m5C profiling across the mammalian transcriptome by bisulfite-free enzyme-assisted chemical labeling approach

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Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus

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Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton

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Spartin-mediated lipid transfer facilitates lipid droplet turnover

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SART3 reads methylarginine-marked glycine- and arginine-rich motifs

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A high-throughput approach to identify BRCA1-downregulating compounds to enhance PARP inhibitor sensitivity

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Assembly and activation of EBV latent membrane protein 1

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Actomyosin organelle functions of SPIRE actin nucleators precede animal evolution

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A mammalian model reveals inorganic polyphosphate channeling into the nucleolus and induction of a hyper-condensate state

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Combination of compound screening with an animal model identifies pentamidine to prevent Chlamydia trachomatis infection

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Original research: IFNγ mediates the resistance of tumor cells to distinct NK cell subsets

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Hotwiring integrin endocytosis acutely modulates cell interactions

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CRISPR/Cas9 screening reveals a distinct class of MHC-I binders with precise HLA-peptide recognition

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Electro-elution-based purification of covalent DNA–protein cross-links

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KMT2A and chronic inflammation as potential drivers of sporadic parathyroid adenoma

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Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule

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Antibody-activation of connexin hemichannels in bone osteocytes with ATP release suppresses breast cancer and osteosarcoma malignancy

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An atlas of human vector-borne microbe interactions reveals pathogenicity mechanisms

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Deciphering ER stress-unfolded protein response relationship by visualizing unfolded proteins in the ER

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Bacterial esterases reverse lipopolysaccharide ubiquitylation to block host immunity

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A Gene‐Switch Platform Interfacing with Reactive Oxygen Species Enables Transcription Fine‐Tuning by Soluble and Volatile Pharmacologics and Food Additives

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Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer

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hnRNPM protects against the dsRNA-mediated interferon response by repressing LINE-associated cryptic splicing

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PolyQ-expanded ataxin-2 aggregation impairs cellular processing-body homeostasis via sequestering the RNA helicase DDX6

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FEBS Press

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Single-cell nanobiopsy enables multigenerational longitudinal transcriptomics of cancer cells

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BPS Publications

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mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway

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mcr-23-0478-html.html

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16a7c226-f27d-4a9e-9485-8d25fbca685c_130126_-_kathleen_southern-html.html

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Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers

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Aurora-A condensation mediated by BuGZ aids its mitotic centrosome functions

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Centriolar satellites are sites of translation of centrosomal and ciliary proteins

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Long non‐coding RNA NEAT1 promotes aerobic glycolysis and progression of cervical cancer through WNT/β‐catenin/PDK1 axis

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Intramolecular autoinhibition regulates the selectivity of PRPF40A tandem WW domains for proline-rich motifs

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Ferroptosis induces membrane blebbing in placental trophoblasts

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Phenotypic targeting using magnetic nanoparticles for rapid characterization of cellular proliferation regulators

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Phenotypic targeting using magnetic nanoparticles for rapid characterization of cellular proliferation regulators

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Comparison of the immunogenicity and protective efficacy of ACAM2000, MVA, and vectored subunit vaccines for Mpox in rhesus macaques

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An ATP13A1-assisted topogenesis pathway for folding multi-spanning membrane proteins

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New AAV9 engineered variants with enhanced neurotropism and reduced liver off-targeting in mice and marmosets

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FEBS Press

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p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol

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p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol

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Multiple ubiquitin ligases protect human genome integrity by targeting cancer-associated APOBEC3 deaminases for degradation

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The Zn2+ transporter ZIP7 enhances endoplasmic-reticulum-associated protein degradation and prevents neurodegeneration in Drosophila

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Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission

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WW domains form a folded type of nuclear localization signal to guide YAP1 nuclear import

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Repurposing AS1411 for constructing ANM-PROTACs

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Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis

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Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis

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Burkholderia thailandensis uses a type VI secretion system to lyse protrusions without triggering host cell responses

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mcr-23-0478-html.html

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Altered GM1 catabolism affects NMDAR-mediated Ca2+ signaling at ER-PM junctions and increases synaptic spine formation in a GM1-gangliosidosis model

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Global, site-resolved analysis of ubiquitylation occupancy and turnover rate reveals systems properties

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Phosphorylation-dependent allosteric regulation of Cx43 gap junction inhibitor potency

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Glutamylation of Npm2 and Nap1 acidic disordered regions increases DNA mimicry and histone chaperone efficiency

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Novel diarylated tacrine derivatives: Synthesis, characterization, anticancer, antiepileptic, antibacterial, and antifungal activities

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A dual role of the conserved PEX19 helix in safeguarding peroxisomal membrane proteins

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Receptor transfer between immune cells by autoantibody-enhanced, CD32-driven trogocytosis is hijacked by HIV-1 to infect resting CD4 T cells

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SRRM2 phase separation drives assembly of nuclear speckle subcompartments

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  ATCC CCL-2
  
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Genetics of cystogenesis in base-edited human organoids reveal therapeutic strategies for polycystic kidney disease

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Nrf2 pre-recruitment at Enhancer 2 is a hallmark of H2 O2 -induced epigenetic transcriptional memory in the HMOX1 gene in human umbilical artery endothelial cells

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Regulation and tumor-suppressive function of the miR-379/miR-656 (C14MC) cluster in cervical cancer

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Live-cell biosensors based on the fluorescence lifetime of environment-sensing dyes

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The Legionella pneumophila effector DenR hijacks the host NRas proto-oncoprotein to downregulate MAPK signaling

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Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum

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Microtubule-associated protein MAP7 promotes tubulin posttranslational modifications and cargo transport to enable osmotic adaptation

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Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator

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A Non-Viral DNA Delivery System Consisting of Multifunctional Chimaeric Peptide Fused with Zinc Finger Protein

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Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling

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Pooled CRISPR screening of high-content cellular phenotypes using ghost cytometry

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RPGR is a guanine nucleotide exchange factor for the small GTPase RAB37 required for retinal function via autophagy regulation

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Endocytic activation and exosomal secretion of matriptase stimulate the second wave of EGF signaling to promote skin and breast cancer invasion

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CXCL17 is an allosteric inhibitor of CXCR4 through a mechanism of action involving glycosaminoglycans

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CXCL17 is an allosteric inhibitor of CXCR4 through a mechanism of action involving glycosaminoglycans

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  DOI: 10.1126/scisignal.abl3758
  
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Light-mediated intracellular polymerization

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Paradoxical imbalance between activated lymphocyte protein synthesis capacity and rapid division rate

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Improved PIEZO1 agonism through 4‐benzoic acid modification of Yoda1

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Stem-loop-induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control

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FLEX: genetically encodable enzymatic fluorescence signal amplification using engineered peroxidase

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The Golgi checkpoint: Golgi unlinking during G2 is necessary for spindle formation and cytokinesis

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The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation

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The immediate-early protein 1 of human herpesvirus 6B interacts with NBS1 and inhibits ATM signaling

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1,10-phenanthroline inhibits sumoylation and reveals that yeast SUMO modifications are highly transient

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Long non-coding RNA MLLT4 antisense RNA 1 induces autophagy to inhibit tumorigenesis of cervical cancer through modulating the myosin-9/ATG14 axis

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Ankrd26 is a retinoic acid-responsive plasma membrane-binding and -shaping protein critical for proper cell differentiation

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A gut-derived hormone regulates cholesterol metabolism

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Thunder-DDA-PASEF enables high-coverage immunopeptidomics and is boosted by MS2Rescore with MS2PIP timsTOF fragmentation prediction model

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Housekeeping U1 snRNA facilitates antiviral innate immunity by promoting TRIM25-mediated RIG-I activation

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A programmable targeted protein-degradation platform for versatile applications in mammalian cells and mice

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Discovery of SQSTM1/p62-dependent P-bodies that regulate the NLRP3 inflammasome

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HDAC5 enhances IRF3 activation and is targeted for degradation by protein C6 from orthopoxviruses including Monkeypox virus and Variola virus

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  ATCCCCL-2
  
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Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide

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PABPC1 mediates degradation of C9orf72-FTLD/ALS GGGGCC repeat RNA

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NEMF-mediated Listerin-independent mitochondrial translational surveillance by E3 ligase Pirh2 and mitochondrial protease ClpXP

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CDK-independent role of D-type cyclins in regulating DNA mismatch repair

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A cellular model provides insights into the pathogenicity of the oncogenic FOXL2 somatic variant p.Cys134Trp

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Securin acetylation prevents precocious separase activation and premature sister chromatid separation

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MOF-mediated acetylation of UHRF1 enhances UHRF1 E3 ligase activity to facilitate DNA methylation maintenance

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Non-canonical isoforms of the mRNA polyadenylation factor WDR33 regulate STING-mediated immune responses

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Human cortical neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression

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Oct4 is a gatekeeper of epithelial identity by regulating cytoskeletal organization in skin keratinocytes

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HERC5-catalyzed ISGylation potentiates cGAS-mediated innate immunity

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SNUPN deficiency causes a recessive muscular dystrophy due to RNA mis-splicing and ECM dysregulation

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A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis

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Design, synthesis and biological evaluation of novel podophyllotoxin derivatives as tubulin-targeting anticancer agents

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Identification of high-performing antibodies for SPARC-related modular calcium-binding protein 1 (SMOC-1) for use in Western Blot and immunoprecipitation

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52.53.155.43/c64b3707ad512c5ae0e1da5ea9afe6057193130c/d14-html.html
52.53.155.43 52.53.155.43

16a7c226-f27d-4a9e-9485-8d25fbca685c_130126_-_kathleen_southern-html.html

2
1. scibot 29 Feb 2024
  
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  CVCL_0030
  
  DOI: 10.5281/zenodo.4724169
  
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2. scibot 29 Feb 2024
  
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  DOI: 10.5281/zenodo.4724169
  
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52.53.155.43/93e1d16e27c8161612933dea24e99e671d4f6f76/5e876839-9f6f-4bea-9e7d-55aa16426283_130126_-_kathleen_southern-html.html
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

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1. scibot 27 Feb 2024
  
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  DOI: 10.1111/febs.17088
  
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febs.onlinelibrary.wiley.com/doi/10.1111/febs.17088
aacrjournals.org aacrjournals.org

First-in-Human Study with preclinical data of BCL-2/BCL-xL Inhibitor Pelcitoclax in Locally Advanced or Metastatic Solid Tumors

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1. scibot 23 Feb 2024
  
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  RRID:CVCL_0030
  
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aacrjournals.org/clincancerres/article/30/3/506/733551/First-in-Human-Study-with-Preclinical-Data-of-BCL
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Plasma membrane damage limits replicative lifespan in yeast and induces premature senescence in human fibroblasts

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nature.com/articles/s43587-024-00575-6
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

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  DOI: 10.1002/1878-0261.13613
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13613
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Integrative modelling and analysis of signalling crosstalk reveal molecular switches coordinating YAP transcriptional activities

1
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  RRID:CVCL_0030
  
  DOI: 10.1016/j.isci.2024.109031
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10877689/
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Shigella induces stress granule formation by ADP-riboxanation of the eIF3 complex

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  DOI: 10.1016/j.celrep.2024.113789
  
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p300 nucleocytoplasmic shuttling underlies mTORC1 hyperactivation in Hutchinson–Gilford progeria syndrome

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1. scibot 21 Feb 2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10866696/
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Mouse oocytes sequester aggregated proteins in degradative super-organelles

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  RRID:CVCL_0030
  
  DOI: 10.1016/j.cell.2024.01.031
  
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sciencedirect.com/science/article/pii/S0092867424000680
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Deposition of onco-histone H3.3-G34W leads to DNA repair deficiency and activates cGAS/STING-mediated immune responses

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1. scibot 18 Feb 2024
  
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  DOI: 10.1002/ijc.34883
  
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onlinelibrary.wiley.com/doi/full/10.1002/ijc.34883
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FEBS Press

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1. scibot 16 Feb 2024
  
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febs.onlinelibrary.wiley.com/doi/10.1111/febs.17015
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The sequence of events of enteropathogenic E. coli’s type III secretion system translocon assembly

1
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  CCL-2ATCC
  
  DOI: 10.1016/j.isci.2024.109108
  
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Redistribution of the glycocalyx exposes phagocytic determinants on apoptotic cells

1
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  ATCCCCL-2
  
  DOI: 10.1016/j.devcel.2024.01.020
  
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sciencedirect.com/science/article/pii/S1534580724000406

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