1,868 Matching Annotations
  1. Aug 2024
  2. elifesciences.org elifesciences.org
    Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling
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    elifesciences.org/content/5/e17047
  3. Jul 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Application of bioluminescence resonance energy transfer assays in primary mouse neuronal cultures
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    sciencedirect.com/science/article/pii/S2666166724003939
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glutathione overproduction mediates lymphoma initiating cells survival and has a sex-dependent effect on lymphomagenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11283572/
  6. www.biorxiv.org www.biorxiv.org
    Presymptomatic Targeted Circuit Manipulation for Ameliorating Huntington’s Disease Pathogenesis
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    biorxiv.org/content/10.1101/2024.07.24.604946v1
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ER calcium depletion as a key driver for impaired ER-to-mitochondria calcium transfer and mitochondrial dysfunction in Wolfram syndrome
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    ncbi.nlm.nih.gov/pmc/articles/PMC11271478/
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    Structural insights into an atypical histone binding mechanism by a PHD finger
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    sciencedirect.com/science/article/pii/S0969212624002351
  9. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004224017851-main-html.html
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    Harnessing the CD44-targeted delivery of self-assembled hyaluronan nanogel to reverse the antagonism between Cisplatin and Gefitinib in NSCLC cancer therapy
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    sciencedirect.com/science/article/pii/S0144861724007471
  11. pathsocjournals.onlinelibrary.wiley.com pathsocjournals.onlinelibrary.wiley.com
    Histone demethylase PHF8 promotes prostate cancer metastasis via the E2F1–SNAI1 axis
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    pathsocjournals.onlinelibrary.wiley.com/doi/full/10.1002/path.6325
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    ‘Radical’ differences between two FLIM microscopes affect interpretation of cell signaling dynamics
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    sciencedirect.com/science/article/pii/S2589004224014937
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16481
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    Biomarker screen for efficacy of oncolytic virotherapy in patient-derived pancreatic cancer cultures
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    thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00254-8/abstract
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    art-14-Ranamalla_Porfire_Tomuta-597-612-html.html
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    MGST3 regulates BACE1 protein translation and amyloidogenesis by controlling the RGS4-mediated AKT signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11332907/
  17. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Altered desensitization and internalization patterns of rodent versus human glucose-dependent insulinotropic polypeptide (GIP) receptors. An important drug discovery challenge
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16478
  18. www.science.org www.science.org
    Engineered mini-G proteins block the internalization of cognate GPCRs and disrupt downstream intracellular signaling
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    science.org/doi/10.1126/scisignal.abq7038
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    SART3 reads methylarginine-marked glycine- and arginine-rich motifs
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    cell.com/cell-reports/abstract/S2211-1247(24)00788-5
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    Arbidol, an antiviral drug, identified as a sodium channel blocker with anticonvulsant activity
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16496
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ser/Thr kinase Trc controls neurite outgrowth in Drosophila by modulating microtubule-microtubule sliding
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    ncbi.nlm.nih.gov/pmc/articles/PMC7021487/
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    Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation
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    sciencedirect.com/science/article/pii/S2211124721001765
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    Assembly and activation of EBV latent membrane protein 1
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    sciencedirect.com/science/article/pii/S0092867424006950
  24. www.cell.com www.cell.com
    Early rhombic lip Protogenin+ve stem cells in a human-specific neurovascular niche initiate and maintain group 3 medulloblastoma
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    cell.com/cell/fulltext/S0092-8674(24)00651-2
  25. www.biorxiv.org www.biorxiv.org
    Evidence for low affinity of GABA at the vesicular monoamine transporter VMAT2 – implications for transmitter co-release from dopamine neurons
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    biorxiv.org/content/10.1101/2024.07.04.602053v1
  26. www.nature.com www.nature.com
    Actomyosin organelle functions of SPIRE actin nucleators precede animal evolution
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    nature.com/articles/s42003-024-06458-1
  27. www.cell.com www.cell.com
    A mammalian model reveals inorganic polyphosphate channeling into the nucleolus and induction of a hyper-condensate state
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    cell.com/cell-reports-methods/fulltext/S2667-2375(24)00179-6
  28. 52.53.155.43 52.53.155.43
    ACKR3 Proximity Labeling Identifies Novel G protein- and β-arrestin-independent GPCR Interacting Proteins
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    52.53.155.43/9259a2c14d17bad8b876c3ec82612338ef6bebf1/2024.01.27.577545v1.full-html.html
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The methyltransferases METTL7A and METTL7B confer resistance to thiol-based histone deacetylase inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11223745/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Photoswitchable positive allosteric modulators of metabotropic glutamate receptor 4 to improve selectivity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11223089/
  31. www.sciencedirect.com www.sciencedirect.com
    Local vascular Klotho mediates diabetes-induced atherosclerosis via ERK1/2 and PI3-kinase-dependent signaling pathways.
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    sciencedirect.com/science/article/pii/S0021915024010992
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: IFNγ mediates the resistance of tumor cells to distinct NK cell subsets
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    ncbi.nlm.nih.gov/pmc/articles/PMC11218003/
  33. journals.asm.org journals.asm.org
    Casein kinase 1α mediates phosphorylation of the Merkel cell polyomavirus large T antigen for β-TrCP destruction complex interaction and subsequent degradation
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    journals.asm.org/doi/10.1128/mbio.01117-24
  34. Jun 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancing structural diversity through chemical engineering of Ambrosia tenuifolia extract for novel anti-glioblastoma compounds
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    ncbi.nlm.nih.gov/pmc/articles/PMC11190268/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural features of heteromeric channels composed of CALHM2 and CALHM4 paralogs
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    ncbi.nlm.nih.gov/pmc/articles/PMC11186629/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant dominant-negative rhodopsin ∆I256 causes protein aggregates degraded via ERAD and prevents normal rhodopsin from proper membrane trafficking
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    ncbi.nlm.nih.gov/pmc/articles/PMC11140085/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Exocyst Complex is Required for the Trafficking and Delivery of KCa3.1 to the Basolateral Membrane of Polarized Epithelia
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    ncbi.nlm.nih.gov/pmc/articles/PMC10243536/
  39. 52.53.155.43 52.53.155.43
    ANGPTL4 Stabilizes Bone Morphogenetic Protein 7 Through Deubiquitination and Promotes HCC Proliferation via the SMAD/MAPK Pathway
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    52.53.155.43/f92318c0d3af1befea25537686d67efa253be56e/bai-et-al-2024-angptl4-stabilizes-bone-morphogenetic-protein-7-through-deubiquitination-and-promotes-hcc-proliferation-html.html
  40. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16433
  41. www.sciencedirect.com www.sciencedirect.com
    Glucagon-like peptide 1 receptor is a T cell-negative costimulatory molecule
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    sciencedirect.com/science/article/pii/S1550413124001773
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16429
  43. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Camelid-derived Tcell engagers harnessing human γδ T cells as promising antitumor immunotherapeutic agents
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    onlinelibrary.wiley.com/doi/10.1002/eji.202350773
  44. 52.53.155.43 52.53.155.43
    KIF22 regulates mitosis and proliferation of chondrocyte cells.
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    52.53.155.43/8c97efa06aaf0f1a9eff0aa7aeb21ad09738dc23/1-s2.0-S2589004224013762-main-html.html
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bacillamide D produced by Bacillus cereus from the mouse intestinal bacterial collection (miBC) is a potent cytotoxin in vitro
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    ncbi.nlm.nih.gov/pmc/articles/PMC11133360/
  46. May 2024
  47. www.sciencedirect.com www.sciencedirect.com
    Human antibodies in Mexico and Brazil neutralizing tick-borne flaviviruses
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    sciencedirect.com/science/article/pii/S2211124724006260
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    Structural basis for inhibition of the lysosomal two-pore channel TPC2 by a small molecule antagonist
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    sciencedirect.com/science/article/pii/S0969212624001825
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Highly variable biological effects of statins on cancer, non-cancer, and stem cells in vitro
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    ncbi.nlm.nih.gov/pmc/articles/PMC11116523/
  50. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Preclinical and translational pharmacology of afucosylated anti-CCR8 antibody for depletion of tumour-infiltrating regulatory T cells
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16326
  51. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Structural bases for stoichiometry-selective calcium potentiation of a neuronal nicotinic receptor
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16321
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epithelial-to-mesenchymal transition and NF-kB pathways are promoted by a mutant form of DDB2, unable to bind PCNA, in UV-damaged human cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11110260/
  53. 52.53.155.43 52.53.155.43
    Normal vision and development in mice with low functional expression of Kir7.1 in heterozygosis for a blindness-producing mutation inactivating the channel
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    52.53.155.43/bd61d1b2a0d7fb97134904bc4e5b10b7c5372ed1/vera-et-al-2024-normal-vision-and-development-in-mice-with-low-functional-expression-of-kir7-1-in-heterozygosis-for-a-html.html
  54. www.sciencedirect.com www.sciencedirect.com
    Potent human monoclonal antibodies targeting Epstein-Barr virus gp42 reveal vulnerable sites for virus infection
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    sciencedirect.com/science/article/pii/S2666379124002659
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    Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
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    sciencedirect.com/science/article/pii/S1097276524003241
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    Autophagy preferentially degrades non-fibrillar polyQ aggregates
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    sciencedirect.com/science/article/pii/S1097276524003836
  57. link.springer.com link.springer.com
    Functional characterization of variants in human ABCC11, an axillary osmidrosis risk factor
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    link.springer.com/article/10.1007/s13577-024-01074-x
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    IL-22 promotes mucin-type O-glycosylation and MATH1+ cell-mediated amelioration of intestinal inflammation
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    sciencedirect.com/science/article/pii/S2211124724005345
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Resf1 is a compound G4 quadruplex-associated tumor suppressor for triple negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11081379/
  60. www.biorxiv.org www.biorxiv.org
    The deubiquitylating enzyme Fat Facets modulates Fat signalling and regulates tissue growth
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    biorxiv.org/content/10.1101/2024.01.27.577535v2
  61. 52.53.155.43 52.53.155.43
    2024.04.30.591961v1.full-html.html
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    Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression
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    sciencedirect.com/science/article/pii/S1550413124001347
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    Ubiquitin-mediated regulation of APE2 protein abundance
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    sciencedirect.com/science/article/pii/S0021925824018386
  64. www.sciencedirect.com www.sciencedirect.com
    On the covalent nature of lysine polyphosphorylation
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    sciencedirect.com/science/article/pii/S1097276524002788
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NANOG controls testicular germ cell tumour stemness through regulation of MIR9-2
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    ncbi.nlm.nih.gov/pmc/articles/PMC11062916/
  66. www.biorxiv.org www.biorxiv.org
    Nucleocytoplasmic transport senses mechanics independently of cell density in cell monolayers
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    biorxiv.org/content/10.1101/2024.01.11.575167v1
  67. 52.53.155.43 52.53.155.43
    Beyond Glycolysis: Aldolase A is a Novel Effector in Reelin Mediated Dendritic Development
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    52.53.155.43/fbcd9c91bc2c853b235998551e36869172c1a2d9/2024.01.12.575269v1.full-html.html
  68. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A triple cysteine motif as major determinant of the modulation of neuronal KV7 channels by the paracetamol metabolite N-acetyl-p-benzo quinone imine
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16380
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Local glycolysis fuels actomyosin contraction during axonal retraction
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    ncbi.nlm.nih.gov/pmc/articles/PMC10616508/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of tumor suppressor TMEM127 drives RET-mediated transformation through disrupted membrane dynamics
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    ncbi.nlm.nih.gov/pmc/articles/PMC11060712/
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A positive feedback inhibition of isocitrate dehydrogenase 3β on paired-box gene 6 promotes Alzheimer-like pathology
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    ncbi.nlm.nih.gov/pmc/articles/PMC11056379/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylation-Driven Epichaperome Assembly: A Critical Regulator of Cellular Adaptability and Proliferation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11030525/
  73. Apr 2024
  74. www.sciencedirect.com www.sciencedirect.com
    Focal clusters of peri-synaptic matrix contribute to activity-dependent plasticity and memory in mice
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    sciencedirect.com/science/article/pii/S2211124724004406
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel Class of Human ADAM8 Inhibitory Antibodies for Treatment of Triple-Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11054802/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LRMP inhibits cAMP potentiation of HCN4 channels by disrupting intramolecular signal transduction
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    ncbi.nlm.nih.gov/pmc/articles/PMC11037915/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human P2X7 receptor variants Gly150Arg and Arg276His polymorphisms have differential effects on risk association and cellular functions in pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11044319/
  78. www.sciencedirect.com www.sciencedirect.com
    CRISPR-Cas9-mediated deletion of carbonic anhydrase 2 in the ciliary body to treat glaucoma
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    sciencedirect.com/science/article/pii/S2666379124001939
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemical cross-linking to study protein self-assembly in cellulo
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    ncbi.nlm.nih.gov/pmc/articles/PMC11059278/
  80. www.liebertpub.com www.liebertpub.com
    Angiopoietin-Related Protein 4-Transcript 3 Increases the Proliferation, Invasion, and Migration of Hepatocellular Carcinoma Cells and Inhibits Apoptosis
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    liebertpub.com/doi/10.1089/dna.2023.0392
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    The MYCN 5′ UTR as a therapeutic target in neuroblastoma
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    sciencedirect.com/science/article/pii/S2211124724004625
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    Collagen IV assembly is influenced by fluid flow in kidney cell-derived matrices
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    sciencedirect.com/science/article/pii/S266729012400024X
  83. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel reuptake inhibitor, IP2015, induces erection by increasing central dopamine and peripheral nitric oxide release
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16362
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    Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice
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    sciencedirect.com/science/article/pii/S2211124724004728
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    Systematic characterization of multi-omics landscape between gut microbial metabolites and GPCRome in Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S221112472400456X
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR editing of anti-anemia drug target rescues independent preclinical models of retinitis pigmentosa
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    ncbi.nlm.nih.gov/pmc/articles/PMC11031380/
  87. aacrjournals.org aacrjournals.org
    miR-217 regulates normal and tumor cell fate following induction of Endoplasmic Reticulum Stress
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    link.springer.com/article/10.1007/s00203-021-02243-4
  176. Dec 2023
  177. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Alpha-synuclein promotes PRMT5-mediated H4R3me2s histone methylation by interacting with the BAF complex
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17037
  178. www.mdpi.com www.mdpi.com
    The Cysteine Protease Legumain Is Upregulated by Vitamin D and Is a Regulator of Vitamin D Metabolism in Mice
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    mdpi.com/2073-4409/13/1/36
  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10740391/
  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Control of CCR5 Cell-Surface Targeting by the PRAF2 Gatekeeper
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    ncbi.nlm.nih.gov/pmc/articles/PMC10744302/
  181. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Mechanisms of aquaporin-4 vesicular trafficking in mammalian cells
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.16029
  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exosome-mediated transfer of circRNA563 promoting hepatocellular carcinoma by targeting the microRNA148a-3p/metal-regulatory transcription factor-1 pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10731156/
  183. www.sciencedirect.com www.sciencedirect.com
    Epinephrine inhibits PI3Kα via the Hippo kinases
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    sciencedirect.com/science/article/pii/S2211124723015474
  184. www.sciencedirect.com www.sciencedirect.com
    An enzyme that selectively S-nitrosylates proteins to regulate insulin signaling
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    sciencedirect.com/science/article/pii/S0092867423012266
  185. www.sciencedirect.com www.sciencedirect.com
    NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance
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    sciencedirect.com/science/article/pii/S2211124723015437
  186. www.sciencedirect.com www.sciencedirect.com
    Profiling nuclear cysteine ligandability and effects on nuclear localization using proximity labeling-coupled chemoproteomics
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    sciencedirect.com/science/article/pii/S2451945623004257
  187. www.sciencedirect.com www.sciencedirect.com
    4.5SH RNA counteracts deleterious exonization of SINE B1 in mice
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    sciencedirect.com/science/article/pii/S1097276523009644
  188. www.sciencedirect.com www.sciencedirect.com
    BACH1 changes microglial metabolism and affects astrogenesis during mouse brain development
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    sciencedirect.com/science/article/pii/S1534580723006160
  189. www.sciencedirect.com www.sciencedirect.com
    Lysosomal dynamics regulate mammalian cortical neurogenesis
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    sciencedirect.com/science/article/pii/S1534580723006196
  190. www.sciencedirect.com www.sciencedirect.com
    IDR-targeting compounds suppress HPV genome replication via disruption of phospho-BRD4 association with DNA damage response factors
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    sciencedirect.com/science/article/pii/S109727652300967X
  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evaluation of the SH-SY5Y cell line as an in vitro model for potency testing of a neuropeptide-expressing AAV vector
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    ncbi.nlm.nih.gov/pmc/articles/PMC10720649/
  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase
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    ncbi.nlm.nih.gov/pmc/articles/PMC10708890/
  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PERK Inhibition by HC-5404 Sensitizes Renal Cell Carcinoma Tumor Models to Antiangiogenic Tyrosine Kinase Inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10690095/