1,803 Matching Annotations
  1. May 2024
  2. 52.53.155.43 52.53.155.43
    Beyond Glycolysis: Aldolase A is a Novel Effector in Reelin Mediated Dendritic Development
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    52.53.155.43/fbcd9c91bc2c853b235998551e36869172c1a2d9/2024.01.12.575269v1.full-html.html
  3. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A triple cysteine motif as major determinant of the modulation of neuronal KV7 channels by the paracetamol metabolite N-acetyl-p-benzo quinone imine
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16380
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Local glycolysis fuels actomyosin contraction during axonal retraction
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    ncbi.nlm.nih.gov/pmc/articles/PMC10616508/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of tumor suppressor TMEM127 drives RET-mediated transformation through disrupted membrane dynamics
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    ncbi.nlm.nih.gov/pmc/articles/PMC11060712/
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    A positive feedback inhibition of isocitrate dehydrogenase 3β on paired-box gene 6 promotes Alzheimer-like pathology
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    ncbi.nlm.nih.gov/pmc/articles/PMC11056379/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylation-Driven Epichaperome Assembly: A Critical Regulator of Cellular Adaptability and Proliferation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11030525/
  8. Apr 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Focal clusters of peri-synaptic matrix contribute to activity-dependent plasticity and memory in mice
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    sciencedirect.com/science/article/pii/S2211124724004406
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    A Novel Class of Human ADAM8 Inhibitory Antibodies for Treatment of Triple-Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11054802/
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    LRMP inhibits cAMP potentiation of HCN4 channels by disrupting intramolecular signal transduction
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    ncbi.nlm.nih.gov/pmc/articles/PMC11037915/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human P2X7 receptor variants Gly150Arg and Arg276His polymorphisms have differential effects on risk association and cellular functions in pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11044319/
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    CRISPR-Cas9-mediated deletion of carbonic anhydrase 2 in the ciliary body to treat glaucoma
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    sciencedirect.com/science/article/pii/S2666379124001939
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    Chemical cross-linking to study protein self-assembly in cellulo
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    ncbi.nlm.nih.gov/pmc/articles/PMC11059278/
  15. www.liebertpub.com www.liebertpub.com
    Angiopoietin-Related Protein 4-Transcript 3 Increases the Proliferation, Invasion, and Migration of Hepatocellular Carcinoma Cells and Inhibits Apoptosis
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    liebertpub.com/doi/10.1089/dna.2023.0392
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    The MYCN 5′ UTR as a therapeutic target in neuroblastoma
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    sciencedirect.com/science/article/pii/S2211124724004625
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    Collagen IV assembly is influenced by fluid flow in kidney cell-derived matrices
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    sciencedirect.com/science/article/pii/S266729012400024X
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    A novel reuptake inhibitor, IP2015, induces erection by increasing central dopamine and peripheral nitric oxide release
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16362
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    Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice
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    sciencedirect.com/science/article/pii/S2211124724004728
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    Systematic characterization of multi-omics landscape between gut microbial metabolites and GPCRome in Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S221112472400456X
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    CRISPR editing of anti-anemia drug target rescues independent preclinical models of retinitis pigmentosa
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    ncbi.nlm.nih.gov/pmc/articles/PMC11031380/
  22. aacrjournals.org aacrjournals.org
    miR-217 regulates normal and tumor cell fate following induction of Endoplasmic Reticulum Stress
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    aacrjournals.org/mcr/article/22/4/360/741846/miR-217-Regulates-Normal-and-Tumor-Cell-Fate
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    The immune suppressor IGSF1 as a potential target for cancer immunotherapy
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    aacrjournals.org/cancerimmunolres/article/12/4/491/741941/The-Immune-Suppressor-IGSF1-as-a-Potential-Target
  24. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2024 - Wang - Differential contributions of G protein‐ or arrestin subtype‐mediated signalling-html.html
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    52.53.155.43/d25c36f4da339833f1e8b168c06cdacd47a35647/British J Pharmacology - 2024 - Wang - Differential contributions of G protein- or arrestin subtype-mediated signalling-html.html
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication
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    ncbi.nlm.nih.gov/pmc/articles/PMC10990277/
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    GPCR kinase subtype requirements for arrestin-2 and -3 translocation to the type-1 cannabinoid receptor and the consequences on G protein signalling
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    sciencedirect.com/science/article/pii/S0006295224001734
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    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16314
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    Genetic or pharmacologic blockade of mPGES-2 attenuates renal lipotoxicity and diabetic kidney disease by targeting Rev-Erbα/FABP5 signaling
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    sciencedirect.com/science/article/pii/S2211124724004030
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Female-specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and estrogen receptor α
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    ncbi.nlm.nih.gov/pmc/articles/PMC11112681/
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    Gut bacteria-driven homovanillic acid alleviates depression by modulating synaptic integrity
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    A novel cancer-germline gene DAZL promotes progression and cisplatin resistance of non-small cell lung cancer by upregulating JAK2 and MCM8
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    sciencedirect.com/science/article/pii/S0378111924003305
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    Pathogenic residue insertion in a neuronal nicotinic receptor alters intra- and inter-subunit interactions that tune channel gating
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    sciencedirect.com/science/article/pii/S0021925824017678
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    TFE3/PI3K/Akt/mTOR axis in renal cell carcinoma affects tumor microenvironment
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    sciencedirect.com/science/article/pii/S0002944024001226
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    Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss
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    sciencedirect.com/science/article/pii/S1550413124000536
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    The UBE2F-CRL5ASB11-DIRAS2 axis is an oncogene and tumor suppressor cascade in pancreatic cancer cells
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    sciencedirect.com/science/article/pii/S1534580724001837
  36. dx.doi.org dx.doi.org
    Genotype-Phenotype Correlations in Thirty Japanese Patients with Congenital Hypothyroidism Attributable to TG Defects
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    dx.doi.org/10.1210/clinem/dgae098
  37. dx.doi.org dx.doi.org
    Structure-Function Analysis of p57KIP2 in the Human Pancreatic Beta Cell Reveals a Bipartite Nuclear Localization Signal
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    dx.doi.org/10.1210/endocr/bqad197
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting of vulnerabilities of drug-tolerant persisters identified through functional genetics delays tumor relapse
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983104/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineering luminopsins with improved coupling efficiencies
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    ncbi.nlm.nih.gov/pmc/articles/PMC10980360/
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    Pharmacological evaluation of new generation OXIZID synthetic cannabinoid receptor agonists
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    sciencedirect.com/science/article/pii/S0014299924002371
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    Modular dual-color BiAD sensors for locus-specific readout of epigenome modifications in single cells
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    sciencedirect.com/science/article/pii/S266723752400064X
  42. Mar 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CXCL17 is an allosteric inhibitor of CXCR4 through a mechanism of action involving glycosaminoglycans
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    ncbi.nlm.nih.gov/pmc/articles/PMC7615768/
  44. www.science.org www.science.org
    CXCL17 is an allosteric inhibitor of CXCR4 through a mechanism of action involving glycosaminoglycans
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    science.org/doi/10.1126/scisignal.abl3758
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extended stop codon context predicts nonsense codon readthrough efficiency in human cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10954755/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC10957175/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Improved PIEZO1 agonism through 4‐benzoic acid modification of Yoda1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10952572/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Assessment of the potential of novel and classical opioids to induce respiratory depression in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10952895/
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    Light regulation of rhodopsin distribution during outer segment renewal in murine rod photoreceptors
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    sciencedirect.com/science/article/pii/S0960982224002525
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular details of ruthenium red pore block in TRPV channels
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    ncbi.nlm.nih.gov/pmc/articles/PMC10897480/
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    First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure
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    sciencedirect.com/science/article/pii/S0092867424002253
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood–brain barrier
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    ncbi.nlm.nih.gov/pmc/articles/PMC10941402/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of hippocampal mossy fiber-CA3 synapse function by a Bcl11b/C1ql2/Nrxn3(25b+) pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10942602/
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    Ankrd26 is a retinoic acid-responsive plasma membrane-binding and -shaping protein critical for proper cell differentiation
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    sciencedirect.com/science/article/pii/S2211124724002675
  55. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    A synthetic flavonoid derivate in the plasma membrane transforms the voltage-clamp fluorometry signal of CiHv1
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17105
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    ADGRG1, an adhesion G protein-coupled receptor, forms oligomers
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17117
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting vulnerable microcircuits in the ventral hippocampus of male transgenic mice to rescue Alzheimer-like social memory loss
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    ncbi.nlm.nih.gov/pmc/articles/PMC10926584/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mapping the substrate landscape of protein phosphatase 2A catalytic subunit PPP2CA
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    ncbi.nlm.nih.gov/pmc/articles/PMC10915630/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-scale requirements for dynein-based transport revealed by a high-content arrayed CRISPR screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC10916854/
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    TET2 Regulation of Alcoholic Fatty Liver via Srebp1 mRNA in Paraspeckles
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    sciencedirect.com/science/article/pii/S2589004224004991
  61. www.nature.com www.nature.com
    Combinatorial selective ER-phagy remodels the ER during neurogenesis
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    nature.com/articles/s41556-024-01356-4
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    Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury
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    Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice
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    Structure-based design of non-hypertrophic apelin receptor modulator
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    The positive allosteric modulator BPAM344 and L-glutamate introduce an active-like structure of the ligand-binding domain of GluK2
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    52.53.155.43/ee21706322a911eb0b4afa11dcb01a5333df7296/FEBS Letters - 2024 - Bay - The positive allosteric modulator BPAM344 and L-glutamate introduce an active-like structure of-html.html
  66. Feb 2024
  67. www.sciencedirect.com www.sciencedirect.com
    DUB3 is a MAGEA3 deubiquitinase and a potential therapeutic target in hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2589004224004024
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    Inhibition of G protein-coupled receptor 68 using homoharringtonine attenuates chronic kidney disease-associated cardiac impairment
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    sciencedirect.com/science/article/pii/S193152442400032X
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    EHBP1 is critically involved in dendritic arbor formation and is coupled to factors promoting actin filament formation
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    jneurosci.org/content/44/6/e0236232023
  70. aacrjournals.org aacrjournals.org
    A novel irreversible TEAD inhibitor, SWTX-143, blocks Hippo pathway transcriptional output and causes tumor regression in preclinical mesothelioma models
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    aacrjournals.org/mct/article/23/1/3/732154/A-Novel-Irreversible-TEAD-Inhibitor-SWTX-143
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    Bioluminescence Imaging Reveals Enhanced SARS-CoV-2 Clearance in Mice with Combinatorial Regimens
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    ncbi.nlm.nih.gov/pmc/articles/PMC10867665/
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    Role of oncogenic long noncoding RNA KCNQ1OT1 in colon cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10865742/
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17015
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    A quantitative pharmacology model for cannabinoid receptor type 1 (CB1) mediated by Gi/Gs protein competition
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16293
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    Applying valency-based immuno-selection to generate broadly cross-reactive antibodies against influenza hemagglutinins
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    link.springer.com/article/10.1038/s41467-024-44889-w
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    Protocol for organelle-specific cysteine capture and quantification of cysteine oxidation state
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    sciencedirect.com/science/article/pii/S2666166724000303
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    Familial Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes
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    An anti-CD19/CTLA-4 switch improves efficacy and selectivity of CAR T cells targeting CD80/86-upregulated DLBCL
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    Human YKT6 forms priming complex with STX17 and SNAP29 to facilitate autophagosome-lysosome fusion
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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkinson’s VPS35[D620N] mutation induces LRRK2-mediated lysosomal association of RILPL1 and TMEM55B
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    ncbi.nlm.nih.gov/pmc/articles/PMC10848721/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mieap forms membrane-less organelles involved in cardiolipin metabolism
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    ncbi.nlm.nih.gov/pmc/articles/PMC10845071/
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    p53 promotes antiviral innate immunity by driving hexosamine metabolism
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    sciencedirect.com/science/article/pii/S2211124724000524
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    Locus-level L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites
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    sciencedirect.com/science/article/pii/S2666979X24000259
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lysosomal stress drives the release of pathogenic α-synuclein from macrophage lineage cells via the LRRK2-Rab10 pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10835446/
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    Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor
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    sciencedirect.com/science/article/pii/S2451945624000382
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nudt21-mediated alternative polyadenylation of MZT1 3’UTR contributes to pancreatic cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831950/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men
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    ncbi.nlm.nih.gov/pmc/articles/PMC10830871/
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    Physical and functional convergence of the autism risk genes Scn2a and Ank2 in neocortical pyramidal cell dendrites
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  180. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  181. Aug 2023
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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  185. link.springer.com link.springer.com
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  195. Jul 2023
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