699 Matching Annotations
  1. Nov 2018
  2. elifesciences.org elifesciences.org
    Structure of the CLC-1 chloride channel from Homo sapiens
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    elifesciences.org/articles/36629
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    elifesciences.org/articles/36478
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    Human LINE-1 retrotransposition requires a metastable coiled coil and a positively charged N-terminus in L1ORF1p
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    ncbi.nlm.nih.gov/pmc/articles/PMC5940361/
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    ncbi.nlm.nih.gov/pmc/articles/PMC6008053/
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    Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies
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    sciencedirect.com/science/article/pii/S1074761317304843
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    In Crystallo Selection to Establish New RNA Crystal Contacts
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    sciencedirect.com/science/article/pii/S0969212618301692
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    EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics
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    sciencedirect.com/science/article/pii/S0092867417310668
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    Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance
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    sciencedirect.com/science/article/pii/S1097276517307153
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    An Alkynyl-Fucose Halts Hepatoma Cell Migration and Invasion by Inhibiting GDP-Fucose-Synthesizing Enzyme FX, TSTA3
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    sciencedirect.com/science/article/pii/S2451945617303215
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    Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin
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    sciencedirect.com/science/article/pii/S1097276518302235
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    Semisynthetic biosensors for mapping cellular concentrations of nicotinamide adenine dinucleotides
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    ncbi.nlm.nih.gov/pmc/articles/PMC5990361/
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    elifesciences.org/articles/36422
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    Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that Mpp6 stimulates RNA decay and recruits the Mtr4 helicase
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    elifesciences.org/articles/29062
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    A Rare Lysozyme Crystal Form Solved Using Highly Redundant Multiple Electron Diffraction Datasets from Micron-Sized Crystals
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    Analysis of Global and Site-Specific Radiation Damage in Cryo-EM
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    sciencedirect.com/science/article/pii/S0969212618301254
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    The Structure of an Infectious Human Polyomavirus and Its Interactions with Cellular Receptors
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    Discrimination against RNA Backbones by a ssDNA Binding Protein
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    elifesciences.org/articles/32893
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    Structure-based membrane dome mechanism for Piezo mechanosensitivity
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    elifesciences.org/articles/33660
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    Targeting Phosphopeptide Recognition by the Human BRCA1 Tandem BRCT Domain to Interrupt BRCA1-Dependent Signaling
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    Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability
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    Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC
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    Robo1 Forms a Compact Dimer-of-Dimers Assembly
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    ncbi.nlm.nih.gov/pmc/articles/PMC5807052/
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    Alternative splice variants of rhomboid proteins: Comparative analysis of database entries for select model organisms and validation of functional potential
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    f1000research.com/articles/7-139
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    Pharmacogenomics of GPCR Drug Targets
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    GroEL Ring Separation and Exchange in the Chaperonin Reaction
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    Repair of UV-Induced DNA Damage Independent of Nucleotide Excision Repair Is Masked by MUTYH
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    HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage
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  35. europepmc.org europepmc.org
    Malaria parasite LIMP protein regulates sporozoite gliding motility and infectivity in mosquito and mammalian hosts.
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    europepmc.org/articles/PMC5438254/
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    A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants
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    europepmc.org/articles/PMC5655547/
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  40. Nov 2017
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia
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    sciencedirect.com/science/article/pii/S1535610817303641
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    The Structure of the ZMYND8/Drebrin Complex Suggests a Cytoplasmic Sequestering Mechanism of ZMYND8 by Drebrin
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    A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential
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    sciencedirect.com/science/article/pii/S0092867417310516
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    A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN
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    sciencedirect.com/science/article/pii/S2451945617302805
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    Genetic identification of a common collagen disease in Puerto Ricans via identity-by-descent mapping in a health system
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    elifesciences.org/articles/25060
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    Structural Basis for Apelin Control of the Human Apelin Receptor
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    Molecular Mechanism of AMPA Receptor Modulation by TARP/Stargazin
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    Autonomous Generation and Loading of DNA Guides by Bacterial Argonaute
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    Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes
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    sciencedirect.com/science/article/pii/S0092867416314672
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    Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins
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    sciencedirect.com/science/article/pii/S0896627317306888
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    Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability
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    Crystal Structure and Regulation of the Citrus Pol III Repressor MAF1 by Auxin and Phosphorylation
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    sciencedirect.com/science/article/pii/S0969212617302198
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    A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45
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    RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks
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    Structural and Functional Insights into Human Re-initiation Complexes
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    Structural Insights into Modulation of Neurexin-Neuroligin Trans-synaptic Adhesion by MDGA1/Neuroligin-2 Complex
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    Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors
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    sciencedirect.com/science/article/pii/S1074761317302297
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    Structure of the ACF7 EF-Hand-GAR Module and Delineation of Microtubule Binding Determinants
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    sciencedirect.com/science/article/pii/S0969212617301405
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    Preprotein Conformational Dynamics Drive Bivalent Translocase Docking and Secretion
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    Heterogeneous Ribosomes Preferentially Translate Distinct Subpools of mRNAs Genome-wide
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    Structural Basis of Egg Coat-Sperm Recognition at Fertilization
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    Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated
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    SAF-A Regulates Interphase Chromosome Structure through Oligomerization with Chromatin-Associated RNAs
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    Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development
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    The Architecture of the Anbu Complex Reflects an Evolutionary Intermediate at the Origin of the Proteasome System
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    Structural Insight into Ubiquitin-Like Protein Recognition and Oligomeric States of JAMM/MPN+ Proteases
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    The Highly Dynamic Nature of ERdj5 Is Key to Efficient Elimination of Aberrant Protein Oligomers through ER-Associated Degradation
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    Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18
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    Dual interaction of scaffold protein Tim44 of mitochondrial import motor with channel-forming translocase subunit Tim23
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    elifesciences.org/articles/23609
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    Structural Studies of HHARI/UbcH7∼Ub Reveal Unique E2∼Ub Conformational Restriction by RBR RING1
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    Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-binding
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    ncbi.nlm.nih.gov/pmc/articles/PMC5413348/
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    Phosphoribosylation of Ubiquitin Promotes Serine Ubiquitination and Impairs Conventional Ubiquitination
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    Changes in the free-energy landscape of p38α MAP kinase through its canonical activation and binding events as studied by enhanced molecular dynamics simulations
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    elifesciences.org/content/6/e22175
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    Conformational Dynamics and Allostery in E2:E3 Interactions Drive Ubiquitination: gp78 and Ube2g2
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    Ion- and water-binding sites inside an occluded hourglass pore of a trimeric intracellular cation (TRIC) channel
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    bmcbiol.biomedcentral.com/articles/10.1186/s12915-017-0372-8
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    Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes
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    ncbi.nlm.nih.gov/pmc/articles/PMC5119991/
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    Human Adaptation of Ebola Virus during the West African Outbreak
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    ncbi.nlm.nih.gov/pmc/articles/PMC5101188/
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    Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores
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    ncbi.nlm.nih.gov/pmc/articles/PMC5101189/
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    Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket
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    5′ End Nicotinamide Adenine Dinucleotide Cap in Human Cells Promotes RNA Decay through DXO-Mediated deNADding
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    Molecular Basis of Substrate Specific Acetylation by N-Terminal Acetyltransferase NatB
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    Mechanism of ribosome rescue by ArfA and RF2
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    elifesciences.org/content/6/e23687
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    Mechanism of Substrate Translocation in an Alternating Access Transporter
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    A Viral Immunoevasin Controls Innate Immunity by Targeting the Prototypical Natural Killer Cell Receptor Family
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    Operon mRNAs are organized into ORF-centric structures that predict translation efficiency
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    ncbi.nlm.nih.gov/pmc/articles/PMC5318159/
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    Target DNA bending by the Mu transpososome promotes careful transposition and prevents its reversal
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    ncbi.nlm.nih.gov/pmc/articles/PMC5357137/
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    Phosphoglycerate Kinase 1 Phosphorylates Beclin1 to Induce Autophagy
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    Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores
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    sciencedirect.com/science/article/pii/S0092867416313861
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    Mitochondrial Ca2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity
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    Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases
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    ncbi.nlm.nih.gov/pmc/articles/PMC5293489/
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    Structure of the Adenosine A1 Receptor Reveals the Basis for Subtype Selectivity
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    sciencedirect.com/science/article/pii/S0092867417301320
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    Nek7 Protects Telomeres from Oxidative DNA Damage by Phosphorylation and Stabilization of TRF1
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    sciencedirect.com/science/article/pii/S1097276517300412
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    S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity
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    Origin of a folded repeat protein from an intrinsically disordered ancestor
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    NusG inhibits RNA polymerase backtracking by stabilizing the minimal transcription bubble
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    ncbi.nlm.nih.gov/pmc/articles/PMC5100998/
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    NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors
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    ncbi.nlm.nih.gov/pmc/articles/PMC5111884/
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    Human Adaptation of Ebola Virus during the West African Outbreak
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    sciencedirect.com/science/article/pii/S0092867416313964