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1,335 Matching Annotations

Dec 2021
academic.oup.com academic.oup.com

Regulation of AKT signaling in mouse uterus

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1. scibot 15 Dec 2021
  
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  DOI: 10.1210/endocr/bqab233
  
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academic.oup.com/endo/article/163/1/bqab233/6430242
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Halofuginone Sensitizes Lung Cancer Organoids to Cisplatin via Suppressing PI3K/AKT and MAPK Signaling Pathways

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1. scibot 11 Dec 2021
  
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  DOI: 10.3389/fcell.2021.773048
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8652204/
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GFAT2 mediates cardiac hypertrophy through HBP-O-GlcNAcylation-Akt pathway

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1. scibot 08 Dec 2021
  
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  DOI: 10.1016/j.isci.2021.103517
  
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sciencedirect.com/science/article/pii/S2589004221014887
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Mitochondrial complex I inhibitors suppress tumor growth through concomitant acidification of the intra- and extracellular environment

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1. scibot 08 Dec 2021
  
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  DOI: 10.1016/j.isci.2021.103497
  
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sciencedirect.com/science/article/pii/S2589004221014681
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The role of epithelial progesterone receptor isoforms in embryo implantation

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1. scibot 08 Dec 2021
  
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  DOI: 10.1016/j.isci.2021.103487
  
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sciencedirect.com/science/article/pii/S2589004221014589
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Glutamine deprivation triggers NAGK-dependent hexosamine salvage

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1. scibot 04 Dec 2021
  
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  DOI: 10.7554/eLife.62644
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8631944/
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FOXO1 represses lymphatic valve formation and maintenance via PRDM1

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1. scibot 01 Dec 2021
  
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  DOI: 10.1016/j.celrep.2021.110048
  
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sciencedirect.com/science/article/pii/S2211124721015345
Nov 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Oligodendrocyte progenitor proliferation is disinhibited following traumatic brain injury in leukemia inhibitory factor heterozygous mice

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1. scibot 25 Nov 2021
  
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  DOI: 10.1002/jnr.24984
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.24984
52.53.155.43 52.53.155.43

japplphysiol.00295.2021-html.html

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1. scibot 24 Nov 2021
  
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  DOI: 10.1152/japplphysiol.00295.2021
  
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52.53.155.43/85154116abc6e4afa906554661d7a2cf52c5921d/japplphysiol.00295.2021-html.html
52.53.155.43 52.53.155.43

ajpheart.00125.2021-html.html

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1. scibot 24 Nov 2021
  
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  DOI: 10.1152/ajpheart.00125.2021
  
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52.53.155.43/97c82e9b6b3864243bc7b06ebc69cb131650363f/ajpheart.00125.2021-html.html
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ajpcell.00385.2020-html.html

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1. scibot 24 Nov 2021
  
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  DOI: 10.1152/ajpcell.00385.2020
  
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52.53.155.43/fcc41b1e6a5d6b11282a20b711b4d6b99930c8bb/ajpcell.00385.2020-html.html
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ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue

1
1. scibot 17 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.110003
  
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sciencedirect.com/science/article/pii/S2211124721014819
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Efferocytosis induces macrophage proliferation to help resolve tissue injury

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1. scibot 16 Nov 2021
  
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  DOI: 10.1016/j.cmet.2021.10.015
  
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sciencedirect.com/science/article/pii/S1550413121005271
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Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction

1
1. scibot 11 Nov 2021
  
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  RRID:AB_2315049
  
  DOI: 10.1016/j.stem.2021.10.009
  
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sciencedirect.com/science/article/pii/S1934590921004215
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Acetyl-CoA derived from hepatic mitochondrial fatty acid β-oxidation aggravates inflammation by enhancing p65 acetylation

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1. scibot 09 Nov 2021
  
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  RRID:AB_2315049
  
  DOI: 10.1016/j.isci.2021.103244
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8551082/
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Dietary nitrate supplementation prevents radiotherapy-induced xerostomia

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1. scibot 09 Nov 2021
  
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  DOI: 10.7554/eLife.70710
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8563005/
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GABAB1e promotes the malignancy of human cancer cells by targeting the tyrosine phosphatase PTPN12

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1. scibot 09 Nov 2021
  
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  DOI: 10.1016/j.isci.2021.103311
  
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sciencedirect.com/science/article/pii/S2589004221012803
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Genomic alterations in PIK3CA-mutated breast cancer result in mTORC1 activation and limit the sensitivity to PI3Kα inhibitors

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1. scibot 05 Nov 2021
  
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  RRID:AB_2315049
  
  DOI: 10.1158/0008-5472.CAN-20-3232
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8137641/
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MiR-552-3p promotes malignant progression of gallbladder carcinoma by reactivating the Akt/β-catenin signaling pathway due to inhibition of the tumor suppressor gene RGMA

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1. scibot 05 Nov 2021
  
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  RRID:AB_2315049
  
  DOI: 10.21037/atm-21-2013
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8506546/
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LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency

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1. scibot 04 Nov 2021
  
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  RRID:AB_2315049
  
  DOI: 10.1016/j.medj.2021.10.002
  
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sciencedirect.com/science/article/pii/S2666634021003421
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Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug

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1. scibot 03 Nov 2021
  
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  RRID:AB_2315049
  
  DOI: 10.1016/j.celrep.2021.109957
  
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sciencedirect.com/science/article/pii/S2211124721014340
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FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma

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1. scibot 03 Nov 2021
  
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  RRID:AB_2315049
  
  DOI: 10.1016/j.celrep.2021.109905
  
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sciencedirect.com/science/article/pii/S2211124721013759
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Electroconvulsive seizure inhibits the mTOR signaling pathway via AMPK in the rat frontal cortex

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1. scibot 02 Nov 2021
  
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  DOI: 10.1007/s00213-021-06015-2
  
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link.springer.com/article/10.1007/s00213-021-06015-2
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Protocol for the assessment of mTOR activity in mouse primary hepatocytes

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1. scibot 02 Nov 2021
  
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  RRID:AB_2315049
  
  DOI: 10.1016/j.xpro.2021.100918
  
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sciencedirect.com/science/article/pii/S2666166721006249
Oct 2021
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Rapamycin recruits SIRT2 for FKBP12 deacetylation during mTOR activity modulation in innate immunity

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1. scibot 29 Oct 2021
  
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  RRID:AB_2315049
  
  DOI: 10.1016/j.isci.2021.103177
  
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sciencedirect.com/science/article/pii/S2589004221011457
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Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2

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1. scibot 29 Oct 2021
  
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  RRID:AB_2315049
  
  DOI: 10.1016/j.isci.2021.103196
  
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sciencedirect.com/science/article/pii/S2589004221011640
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Rapamycin targets STAT3 and impacts c-Myc to suppress tumor growth

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1. scibot 27 Oct 2021
  
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  DOI: 10.1016/j.chembiol.2021.10.006
  
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sciencedirect.com/science/article/pii/S2451945621004402
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Bletinib ameliorates neutrophilic inflammation and lung injury by inhibiting Src family kinase phosphorylation and activity

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1. scibot 23 Oct 2021
  
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  DOI: 10.1111/bph.15597
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8518616/
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Glycogen accumulation and phase separation drives liver tumor initiation

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1. scibot 22 Oct 2021
  
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  RRID:AB_2315049
  
  DOI: 10.1016/j.cell.2021.10.001
  
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sciencedirect.com/science/article/pii/S0092867421011752
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PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory

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1. scibot 22 Oct 2021
  
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  RRID:AB_231504
  
  DOI: 10.1016/j.celrep.2021.109804
  
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  Curator comments: Phospho-Akt (Ser473) (D9E) XP® Rabbit mAb antibody Cell Signaling Technology Cat# 4060
  
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sciencedirect.com/science/article/pii/S221112472101264X
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RNF8-mediated regulation of Akt promotes lung cancer cell survival and resistance to DNA damage

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1. scibot 21 Oct 2021
  
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  DOI: 10.1016/j.celrep.2021.109854
  
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sciencedirect.com/science/article/pii/S2211124721013218
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Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis

1
1. scibot 21 Oct 2021
  
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  DOI: 10.1016/j.celrep.2021.109870
  
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sciencedirect.com/science/article/pii/S2211124721013371
josr-online.biomedcentral.com josr-online.biomedcentral.com

Overexpression of FGF2 delays the progression of osteonecrosis of the femoral head activating the PI3K/Akt signaling pathway

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1. scibot 19 Oct 2021
  
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  DOI: 10.1186/s13018-021-02715-9
  
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josr-online.biomedcentral.com/articles/10.1186/s13018-021-02715-9
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A role for AKT1 in nonsense-mediated mRNA decay

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1. scibot 15 Oct 2021
  
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  4060
  
  DOI: 10.1093/nar/gkab882
  
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  RRIDCUR:Missing RRID:AB_2315049
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academic.oup.com/nar/advance-article/doi/10.1093/nar/gkab882/6389627
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Bioenergetic Requirements and Spatiotemporal Profile of Nerve Growth Factor Induced PI3K-Akt Signaling Along Sensory Axons

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1. scibot 13 Oct 2021
  
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  DOI: 10.3389/fnmol.2021.726331
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8497901/
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Proteomics reveal cap-dependent translation inhibitors remodel the translation machinery and translatome

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1. scibot 13 Oct 2021
  
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  RRID:AB_2315049
  
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Serum- and glucocorticoid-induced kinase drives hepatic insulin resistance by directly inhibiting AMP-activated protein kinase

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Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice

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Wnt5a Regulates Junctional Function of Sertoli cells Through PCP-Mediated Effects on mTORC1 and mTORC2

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Preclinical and Clinical Characterization of Fibroblast-derived Neuregulin-1 on Trastuzumab and Pertuzumab Activity in HER2-positive Breast Cancer

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Involvement of multiple scavenger receptors in advanced glycation end product-induced vessel tube formation in endothelial cells

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Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice

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H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity

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The pro-regenerative effects of hyperIL6 in drug-induced liver injury are unexpectedly due to competitive inhibition of IL11 signaling

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Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche

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SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 to direct pro-inflammatory signaling in TLR-activated macrophages

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Treatment of acromegaly by rosiglitazone via upregulating 15-PGDH in both pituitary adenoma and liver

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BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology

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Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors

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Coordination of tumor growth and host wasting by tumor-derived Upd3

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NGPF2 triggers synaptic scaling up through ALK-LIMK-cofilin-mediated mechanisms

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Functional diagnostics using fresh uncultured lung tumor cells to guide personalized treatments

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The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway

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Hormonally regulated myogenic miR-486 influences sex-specific differences in cancer-induced skeletal muscle defects

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Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system

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Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis

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A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies

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Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines

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Multiple regulatory intrinsically disordered motifs control FOXO4 transcription factor binding and function

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A fluorescent reporter assay of differential gene expression response to insulin in hepatocytes

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Chronic VEGFR-3 signaling preserves dendritic arborization and sensitization under stress

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KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance

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Food Perception Primes Hepatic ER Homeostasis via Melanocortin-Dependent Control of mTOR Activation

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Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations

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Decreased rates of cerebral protein synthesis measured in vivo in a mouse model of Tuberous Sclerosis Complex: unexpected consequences of reduced tuberin

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Fendiline Enhances the Cytotoxic Effects of Therapeutic Agents on PDAC Cells by Inhibiting Tumor-Promoting Signaling Events: A Potential Strategy to Combat PDAC

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Artemisinin inhibits NRas palmitoylation by targeting the protein acyltransferase ZDHHC6

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Differential Actions of Estrogen Receptor α and β via Non-Genomic Signaling in Human Prostate Stem and Progenitor Cells

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Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis

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Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn’s disease

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T-cell–derived extracellular vesicles regulate B-cell IgG production via pyruvate kinase muscle isozyme 2

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The Parkinson's gene PINK1 activates Akt via PINK1 kinase-dependent regulation of the phospholipid PI(3,4,5)P3

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Sex difference in corticosterone-induced insulin resistance in mice

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CDK12 drives breast tumor initiation and trastuzumab resistance via WNT and IRS1‐ErbB‐PI3K signaling

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Nuclear PGK1 Alleviates ADP-Dependent Inhibition of CDC7 to Promote DNA Replication

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Effects of the presence and absence of amino acids on translation, signaling and long‐term depression in hippocampal slices from Fmr1 knockout mice

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Use of nonsteroidal anti-inflammatory drugs predicts improved patient survival for PIK3CA-altered head and neck cancer

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TrkB‐mediated activation of the phosphatidylinositol‐3‐kinase/Akt cascade reduces the damage inflicted by oxygen‐glucose deprivation in area CA3 of the rat hippocampus

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Akt3-mTOR regulates hippocampal neurogenesis in adult mouse

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Inactivation of Tp53 and Pten drives rapid development of pleural and peritoneal malignant mesotheliomas

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PTEN negatively regulates the cell lineage progression from NG2+ glial progenitor to oligodendrocyte via mTOR-independent signaling

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Vascular Endothelial Growth Factor–D (VEGF-D) Overexpression and Lymphatic Expansion in Murine Adipose Tissue Improves Metabolism in Obesity

1
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  AB_2315049
  
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Systemic network analysis identifies XIAP and IκBα as potential drug targets in TRAIL resistant BRAF mutated melanoma

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Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness

1
1. scibot 28 Jul 2021
  
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  Phospho-Akt (Ser473) (D9E) XPu00a0Rabbit mAb
  
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PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K

1
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Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling

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PTEN knockdown alters dendritic spine/protrusion morphology, not density

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  Anti-pAKTMonoclonalRabbitEpitope surrounds serine 473 of AKT sequence1:200Cell Signaling4060AB_916027
  
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cell.com/developmental-cell/abstract/S1534-5807(17)30871-7
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Brain Endothelial Cells Maintain Lactate Homeostasis and Control Adult Hippocampal Neurogenesis

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OVA66 promotes tumour angiogenesis and progression through enhancing autocrine VEGF-VEGFR2 signalling

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  DOI: 10.1016/j.neuron.2018.10.051
  
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Dynamic Phosphorylation of the C Terminus of Hsp70 Regulates the Mitochondrial Import of SOD2 and Redox Balance

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  RRID:AB_2750995
  
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Angiotensin-II-induced Muscle Wasting is Mediated by 25-Hydroxycholesterol via GSK3β Signaling Pathway

1
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  AB_916024
  
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Neuroplasticity and inflammatory alterations in the nucleus accumbens are corrected after risperidone treatment in a schizophrenia-related developmental model in rats

1
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Phosphatidylinositol-3 kinase mediates the sweet suppressive effect of leptin in mouse taste cells

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Thyroid hormone receptor beta inhibits the PI3K-Akt-mTOR signaling axis in anaplastic thyroid cancer cell lines via genomic mechanisms

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Microscopic image-based covariation network analysis for actin scaffold-modified insulin signaling

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An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress

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Brain endothelial PTEN/AKT/NEDD4-2/MFSD2A axis regulates blood-brain barrier permeability

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IL-17 Inhibits Oligodendrocyte Progenitor Cell Proliferation and Differentiation by Increasing K+ Channel Kv1.3

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Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target

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  4060
  
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Synchronous effects of targeted mitochondrial complex I inhibitors on tumor and immune cells abrogate melanoma progression

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OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin

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Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma

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Canonical NF-κB signaling maintains corneal epithelial integrity and prevents corneal aging via retinoic acid

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  DOI: 10.7554/eLife.67315
  
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Gut microbiota-CRAMP axis shapes intestinal barrier function and immune responses in dietary gluten-induced enteropathy

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β-elemene alleviates airway stenosis via the ILK/Akt pathway modulated by MIR143HG sponging miR-1275

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A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways

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MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages

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NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma

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FEBS Press

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Targeted mass-spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP kinase, and AKT signaling

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Target identification for small-molecule discovery in the FOXO3a tumor-suppressor pathway using a biodiverse peptide library

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TMBIM1 is an inhibitor of adipogenesis and its depletion promotes adipocyte hyperplasia and improves obesity-related metabolic disease

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Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma

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Reprogramming an energetic AKT-PAK5 axis boosts axon energy supply and facilitates neuron survival and regeneration after injury and ischemia

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Mismatch repair deficiency predicts response to HER2 blockade in HER2-negative breast cancer

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The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding

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Limited inhibition of multiple nodes in a driver network blocks metastasis

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A novel oncotherapy strategy: Direct thrombin inhibitors suppress progression, dissemination and spontaneous metastasis in non-small cell lung cancer

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UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling

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Hepatic AKT orchestrates adipose tissue thermogenesis via FGF21-dependent and -independent mechanisms

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The E3 ligase TRAF4 Promotes IGF Signaling by Mediating Atypical Ubiquitination of IRS-1

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NC1-peptide from collagen α3 (IV) chains in the basement membrane of testes regulates spermatogenesis via p-FAK-Y407

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SMRT Regulates Metabolic Homeostasis and Adipose Tissue Macrophage Phenotypes in Tandem

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Heparan Sulfate Synthesized by Ext1 Regulates Receptor Tyrosine Kinase Signaling and Promotes Resistance to EGFR Inhibitors in GBM

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Removal of epididymal visceral adipose tissue prevents obesity-induced multi-organ insulin resistance in male mice

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Specific inhibition of oncogenic RAS using cell-permeable RAS-binding domains

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BPS Publications

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Hdac9 inhibits medial artery calcification through down-regulation of Osterix

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Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation

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Integrin-Linked Kinase Mediates Therapeutic Resistance of Quiescent CML Stem Cells to Tyrosine Kinase Inhibitors

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Thymoquinone administration ameliorates Alzheimer's disease-like phenotype by promoting cell survival in the hippocampus of amyloid beta1-42 infused rat model

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Akt-mTOR hypoactivity in bipolar disorder gives rise to cognitive impairments associated with altered neuronal structure and function

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Serotonin Receptor 2A Activation Promotes Evolutionarily Relevant Basal Progenitor Proliferation in the Developing Neocortex

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Control of Glucocorticoid Receptor Levels by PTEN Establishes a Failsafe Mechanism for Tumor Suppression

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Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases

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Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy

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An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells

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Anti-inflammatory Roles of Glucocorticoids Are Mediated by Foxp3+ Regulatory T Cells via a miR-342-Dependent Mechanism

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The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction

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An Excitable Ras/PI3K/ERK Signaling Network Controls Migration and Oncogenic Transformation in Epithelial Cells

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Parvalbumin affects skeletal muscle trophism through modulation of mitochondrial calcium uptake

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  DOI: 10.1016/j.celrep.2021.109087
  
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Metabolic stress drives sympathetic neuropathy within the liver

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  DOI: 10.1016/j.cmet.2021.01.012
  
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Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations

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1. scibot 30 Apr 2021
  
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  DOI: 10.1016/j.ccell.2021.03.012
  
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Obesity-Linked PPARγ S273 Phosphorylation Promotes Insulin Resistance through Growth Differentiation Factor 3

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  rabbit anti-phospho-Akt Ser473
  
  DOI: 10.1016/j.cmet.2020.08.016
  
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Dissociation of Muscle Insulin Resistance from Alterations in Mitochondrial Substrate Preference

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  DOI: 10.1016/j.cmet.2020.09.008
  
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A Membrane-Bound Diacylglycerol Species Induces PKCϵ-Mediated Hepatic Insulin Resistance

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  DOI: 10.1016/j.cmet.2020.08.001
  
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Glutamine deficiency promotes stemness and chemoresistance in tumor cells through DRP1-induced mitochondrial fragmentation

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  DOI: 10.1007/s00018-021-03818-6
  
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Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade

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Dipyridamole Inhibits Lipogenic Gene Expression by Retaining SCAP-SREBP in the Endoplasmic Reticulum

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An Organoid Biobank of Neuroendocrine Neoplasms Enables Genotype-Phenotype Mapping

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  DOI: 10.1016/j.cell.2020.10.023
  
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Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer

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  DOI: 10.1016/j.cell.2020.10.016
  
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Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells

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  DOI: 10.1016/j.cell.2020.02.003
  
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A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation

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Cell Lineage-Based Stratification for Glioblastoma

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SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways

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Regulation of PTEN translation by PI3K signaling maintains pathway homeostasis

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  DOI: 10.1016/j.molcel.2021.01.033
  
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Blocking Fra-1 sensitizes triple-negative breast cancer to PARP inhibitor

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  DOI: 10.1016/j.canlet.2021.02.018
  
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Metabolomic analysis of a selective ABCA1 inducer in obesogenic challenge provides a rationale for therapeutic development

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  DOI: 10.1016/j.ebiom.2021.103287
  
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S1PR3–G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation

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  DOI: 10.1016/j.chembiol.2021.01.004
  
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SGK1 signaling promotes glucose metabolism and survival in extracellular matrix detached cells

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  DOI: 10.1016/j.celrep.2021.108821
  
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