1,434 Matching Annotations
  1. Jan 2022
  2. www.sciencedirect.com www.sciencedirect.com
    Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses
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    1. scibot 11 Jan 2022
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    sciencedirect.com/science/article/pii/S1097276521010686
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    Skeletal muscle phenotyping of Hippo gene-mutated mice reveals that Lats1 deletion increases the percentage of type I muscle fibers
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    1. scibot 06 Jan 2022
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      DOI: 10.1007/s11248-021-00293-4

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    link.springer.com/article/10.1007/s11248-021-00293-4
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    4-Phenylbutyrate restores localization and membrane repair to human dysferlin mutations
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    1. scibot 06 Jan 2022
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      DOI: 10.1016/j.isci.2021.103667

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    ncbi.nlm.nih.gov/pmc/articles/PMC8741482/
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    A purine metabolic checkpoint that prevents autoimmunity and autoinflammation
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    1. scibot 05 Jan 2022
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    sciencedirect.com/science/article/pii/S1550413121006288
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    AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia
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    1. scibot 05 Jan 2022
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    sciencedirect.com/science/article/pii/S2211124721017010
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    STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses
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    sciencedirect.com/science/article/pii/S1550413121006264
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    E3 Ubiquitin Ligase Nedd4-2 Exerts Neuroprotective Effects During Endoplasmic Reticulum Stress
    1
    1. scibot 02 Jan 2022
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      DOI: 10.1111/jnc.15567

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.15567
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    <p>Dynamics of Endocytosis and Degradation of Antibody-Drug Conjugate T-DM1 in HER2 Positive Cancer Cells</p>
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  10. Dec 2021
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    Translational and post-translational control of human naïve versus primed pluripotency
    1
    1. scibot 30 Dec 2021
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    sciencedirect.com/science/article/pii/S2589004221016151
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    Intrauterine growth restriction elevates circulating acylcarnitines and suppresses fatty-acid metabolism genes in the fetal sheep heart
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    1. scibot 22 Dec 2021
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP281415
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    3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis
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    1. scibot 22 Dec 2021
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    sciencedirect.com/science/article/pii/S2451945621005201
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    Thiol-based functional mimicry of phosphorylation of the two-component system response regulator ArcA promotes pathogenesis in enteric pathogens
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    1. scibot 22 Dec 2021
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    sciencedirect.com/science/article/pii/S2211124721016430
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    BPS Publications
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    1. scibot 21 Dec 2021
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      DOI: 10.1111/bph.15741

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15741
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    Low-intensity pulsed ultrasound-generated singlet oxygen induces telomere damage leading to glioma stem cell awakening from quiescence
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    1. scibot 18 Dec 2021
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      DOI: 10.1016/j.isci.2021.103558

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    sciencedirect.com/science/article/pii/S2589004221015285
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    β-catenin links cell seeding density to global gene expression during mouse embryonic stem cell differentiation
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    1. scibot 17 Dec 2021
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    sciencedirect.com/science/article/pii/S2589004221015121
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    Hydrogen sulfide blocks HIV rebound by maintaining mitochondrial bioenergetics and redox homeostasis
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    1. scibot 15 Dec 2021
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      DOI: 10.7554/eLife.68487

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    elifesciences.org/articles/68487
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    Olfactory receptor 5B21 drives breast cancer metastasis
    1
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      DOI: 10.1016/j.isci.2021.103519

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    sciencedirect.com/science/article/pii/S2589004221014905
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of extracellular microRNA-146a-5p in host innate immunity and bacterial sepsis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8633977/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation
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    1. scibot 11 Dec 2021
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      DOI: 10.7554/eLife.70715

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    ncbi.nlm.nih.gov/pmc/articles/PMC8641947/
  22. elifesciences.org elifesciences.org
    Experiments from unfinished Registered Reports in the Reproducibility Project: Cancer Biology
    1
    1. scibot 11 Dec 2021
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      DOI: 10.7554/eLife.73430

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    elifesciences.org/articles/73430
  23. www.sciencedirect.com www.sciencedirect.com
    Interleukin-17 affects synaptic plasticity and cognition in an experimental model of multiple sclerosis
    1
    1. scibot 09 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110094

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    sciencedirect.com/science/article/pii/S2211124721015886
  24. academic.oup.com academic.oup.com
    Calcium-Sensing Receptors Control CYP27B1-Luciferase Expression: Transcriptional and Posttranscriptional Mechanisms
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    1. scibot 03 Dec 2021
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      DOI: 10.1210/jendso/bvab057

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    academic.oup.com/jes/article/5/9/bvab057/6293989
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    NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation
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    1. scibot 03 Dec 2021
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      DOI: 10.1016/j.cell.2021.11.011

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    sciencedirect.com/science/article/pii/S009286742101326X
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic and experimental evidence that ALKATI does not predict single agent sensitivity to ALK inhibitors
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      DOI: 10.1016/j.isci.2021.103343

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    ncbi.nlm.nih.gov/pmc/articles/PMC8603052/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolism of cancer cells commonly responds to irradiation by a transient early mitochondrial shutdown
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      DOI: 10.1016/j.isci.2021.103366

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    ncbi.nlm.nih.gov/pmc/articles/PMC8603201/
  28. Nov 2021
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elucidation and refinement of synthetic receptor mechanisms
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    1. scibot 29 Nov 2021
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      DOI: 10.1093/synbio/ysaa017

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    ncbi.nlm.nih.gov/pmc/articles/PMC7759213/
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    Force-dependent activation of actin elongation factor mDia1 protects the cytoskeleton from mechanical damage and promotes stress fiber repair
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    1. scibot 25 Nov 2021
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      DOI: 10.1016/j.devcel.2021.11.004

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    sciencedirect.com/science/article/pii/S1534580721008893
  31. 52.53.155.43 52.53.155.43
    japplphysiol.00295.2021-html.html
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      DOI: 10.1152/japplphysiol.00295.2021

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    The ESCRT machinery counteracts Nesprin-2G-mediated mechanical forces during nuclear envelope repair
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    1. scibot 24 Nov 2021
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      DOI: 10.1016/j.devcel.2021.10.022

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    sciencedirect.com/science/article/pii/S1534580721008534
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    A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization
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      DOI: 10.1016/j.molcel.2021.10.017

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    sciencedirect.com/science/article/pii/S1097276521009096
  34. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The multicellular signalling network of ovarian cancer metastases
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    onlinelibrary.wiley.com/doi/10.1002/ctm2.633
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    Integrated genomic and proteomic analyses identify stimulus-dependent molecular changes associated with distinct modes of skeletal muscle atrophy
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    sciencedirect.com/science/article/pii/S2211124721014509
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    A patch of positively charged residues regulates the efficacy of clinical DR5 antibodies in solid tumors
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    GABAB1e promotes the malignancy of human cancer cells by targeting the tyrosine phosphatase PTPN12
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    sciencedirect.com/science/article/pii/S2589004221012803
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    Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease
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  39. www.nature.com www.nature.com
    AKIRIN2 controls the nuclear import of proteasomes in vertebrates
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      DOI: 10.1038/s41586-021-04035-8

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    nature.com/articles/s41586-021-04035-8
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC1A5 provides glutamine and asparagine necessary for bone development in mice
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      DOI: 10.7554/eLife.71595

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    ncbi.nlm.nih.gov/pmc/articles/PMC8553342/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells
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      DOI: 10.1016/j.ebiom.2021.103646

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    ncbi.nlm.nih.gov/pmc/articles/PMC8546421/
  42. 52.53.155.43 52.53.155.43
    ajpcell.00116.2021-html.html
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      DOI: 10.1021/ja00738a045.

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    Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug
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      DOI: 10.1016/j.celrep.2021.109957

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    sciencedirect.com/science/article/pii/S2211124721014340
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    Impaired glucocorticoid receptor expression in liver disrupts feeding-induced gene expression, glucose uptake, and glycogen storage
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    Melatonin Analogues Potently Inhibit MAO-B and Protect PC12 Cells against Oxidative Stress
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    GCN2 adapts protein synthesis to scavenging-dependent growth
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    Metformin alleviates stress-induced cellular senescence of aging human adipose stromal cells and the ensuing adipocyte dysfunction
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    Early resistance training-mediated stimulation of daily muscle protein synthetic responses to higher habitual protein intake in middle-aged adults
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    L-cell Arntl is required for rhythmic glucagon-like peptide-1 secretion and maintenance of intestinal homeostasis
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    Differences in Glycolysis and Mitochondrial Respiration between Cytotrophoblast and Syncytiotrophoblast In-Vitro: Evidence for Sexual Dimorphism
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    Site-specific N-glycosylation of integrin α2 mediates collagen-dependent cell survival
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    Proteomics reveal cap-dependent translation inhibitors remodel the translation machinery and translatome
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    Humanin-induced autophagy plays important roles in skeletal muscle function and lifespan extension
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    Inhibition of HIV infection by structural proteins of the inner nuclear membrane is associated with reduced chromatin dynamics
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    Noncanonical mono(ADP-ribosyl)ation of zinc finger SZF proteins counteracts ubiquitination for protein homeostasis in plant immunity
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    Roles of autophagy in relation to mitochondrial stress responses of HeLa cells to lamellarin cytotoxicity
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    Low folate induces abnormal neuronal maturation and DNA hypomethylation of neuronal differentiation-related genes in cultured mouse neural stem and progenitor cells
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    CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models
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    The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation
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    Efficient Generation of Multi-gene Knockout Cell Lines and Patient-derived Xenografts Using Multi-colored Lenti-CRISPR-Cas9
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    Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species
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    Mutant U2AF1-induced alternative splicing of H2afy (macroH2A1) regulates B-lymphopoiesis in mice
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    Epigenomic and transcriptional profiling identifies impaired glyoxylate detoxification in NAFLD as a risk factor for hyperoxaluria
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    Cdc42 is required for male germline niche development in mice
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    The histone chaperone Anp32e regulates memory formation, transcription, and dendritic morphology by regulating steady-state H2A.Z binding in neurons
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    Actinin BioID reveals sarcomere crosstalk with oxidative metabolism through interactions with IGF2BP2
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    Predicted Benign and Synonymous Variants in CYP11A1 Cause Primary Adrenal Insufficiency Through Missplicing
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  133. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Role of GluN2A NMDA receptor in homocysteine‐induced prostaglandin E2 release from neurons
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  134. www.nature.com www.nature.com
    Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction
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      HRP-anti-mouse IgG antibody

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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells
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    Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis
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    CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors
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    MicroRNA501‐5p induces p53 proteasome degradation through the activation of the mTOR/MDM2 pathway in ADPKD cells
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    Endoplasmic Reticulum Stress Activated by Androgen Enhances Apoptosis of Granulosa Cells via Induction of Death Receptor 5 in PCOS
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    A structure-specific small molecule inhibits a miRNA-200 family member precursor and reverses a type 2 diabetes phenotype
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    Conformational Change in the Ligand-Binding Pocket via a KISS1R Mutation (P147L) Leads to Isolated Gonadotropin-Releasing Hormone Deficiency
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    An ShRNA Screen Identifies MEIS1 as a Driver of Malignant Peripheral Nerve Sheath Tumors
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    Arid1a Has Context-Dependent Oncogenic and Tumor Suppressor Functions in Liver Cancer
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  153. rupress.org rupress.org
    Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination
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    An optogenetic proximity labeling approach to probe the composition of inducible biomolecular condensates in cultured cells
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    Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy
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    Peroxisomes in the mouse parotid glands: An in-depth morphological and molecular analysis
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    β2-microglobulin triggers NLRP3 inflammasome activation in tumor-associated macrophages to promote multiple myeloma progression
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  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KY19382, a novel activator of Wnt/β‐catenin signalling, promotes hair regrowth and hair follicle neogenesis
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    Thyroid hormone receptor beta inhibits the PI3K-Akt-mTOR signaling axis in anaplastic thyroid cancer cell lines via genomic mechanisms
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    Site-specific O-GlcNAcylation of Psme3 maintains mouse stem cell pluripotency by impairing P-body homeostasis
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  162. www.cell.com www.cell.com
    Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer
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  163. Jun 2021
  164. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial-derived vesicles compensate for loss of LC3-mediated mitophagy
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    Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
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  166. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Mutations in the IFNγ-JAK-STAT pathway causing resistance to immune checkpoint inhibitors in melanoma increase sensitivity to oncolytic virus treatment.
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  167. www.hindawi.com www.hindawi.com
    Table 2 | Saussureae Radix Attenuates Neuroinflammation in LPS-Stimulated Mouse BV2 Microglia via HO-1/Nrf-2 Induction and Inflammatory Pathway Inhibition
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    LC3B phosphorylation regulates FYCO1 binding and directional transport of autophagosomes
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  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Arhgef2 regulates neural differentiation in the cerebral cortex through mRNA m6A-methylation of Npdc1 and Cend1
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  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver
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    Loss of tRNA-modifying enzyme Elp3 activates a p53-dependent antitumor checkpoint in hematopoiesis
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    Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling
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